Mus musculus

100 known processes

Hfe2

hemochromatosis type 2 (juvenile) (human homolog)

(Aliases: HJV,2310035L15Rik,AI789733,DL-M,Rgmc,hemojuvelin,AI414844,5230400G09Rik)

Hfe2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
actin cytoskeleton organization GO:0030036 220 0.274
metal ion homeostasis GO:0055065 189 0.251
cation homeostasis GO:0055080 212 0.164
muscle contraction GO:0006936 101 0.140
myosin filament organization GO:0031033 3 0.122
muscle tissue development GO:0060537 308 0.109
cellular metal ion homeostasis GO:0006875 151 0.107
wound healing GO:0042060 157 0.103
cellular amino acid metabolic process GO:0006520 103 0.099
protein processing GO:0016485 163 0.095
amine metabolic process GO:0009308 45 0.094
cellular amine metabolic process GO:0044106 44 0.088
striated muscle myosin thick filament assembly GO:0071688 1 0.086
myosin filament assembly GO:0031034 2 0.082
anion transport GO:0006820 177 0.079
fibrinolysis GO:0042730 3 0.077
organonitrogen compound biosynthetic process GO:1901566 192 0.077
transmembrane transport GO:0055085 412 0.074
regulation of cellular ketone metabolic process GO:0010565 66 0.072
inorganic ion transmembrane transport GO:0098660 234 0.072
organelle assembly GO:0070925 177 0.072
muscle cell differentiation GO:0042692 261 0.069
homeostasis of number of cells GO:0048872 210 0.069
striated muscle contraction GO:0006941 45 0.067
cofactor biosynthetic process GO:0051188 41 0.067
cellular nitrogen compound catabolic process GO:0044270 280 0.063
cation transport GO:0006812 399 0.063
muscle system process GO:0003012 141 0.063
cofactor metabolic process GO:0051186 80 0.061
heterocycle catabolic process GO:0046700 280 0.059
bmp signaling pathway GO:0030509 93 0.059
organic acid transport GO:0015849 101 0.058
cellular ketone metabolic process GO:0042180 84 0.058
striated muscle cell development GO:0055002 125 0.056
nucleobase containing small molecule metabolic process GO:0055086 352 0.056
cellular component assembly involved in morphogenesis GO:0010927 139 0.056
regulation of system process GO:0044057 200 0.055
cation transmembrane transport GO:0098655 266 0.055
regulation of hydrolase activity GO:0051336 246 0.055
porphyrin containing compound metabolic process GO:0006778 22 0.055
skeletal myofibril assembly GO:0014866 4 0.052
oxidation reduction process GO:0055114 342 0.052
regulation of muscle system process GO:0090257 80 0.051
regulation of cellular amino acid metabolic process GO:0006521 5 0.050
regulation of cellular amine metabolic process GO:0033238 20 0.049
cellular ion homeostasis GO:0006873 165 0.049
striated muscle tissue development GO:0014706 293 0.049
blood coagulation GO:0007596 76 0.049
organic cyclic compound catabolic process GO:1901361 295 0.048
tetrapyrrole metabolic process GO:0033013 22 0.048
lipid biosynthetic process GO:0008610 179 0.047
regulation of actin filament based process GO:0032970 99 0.047
myeloid cell homeostasis GO:0002262 114 0.047
circulatory system process GO:0003013 197 0.046
t cell activation GO:0042110 289 0.046
nucleoside monophosphate metabolic process GO:0009123 85 0.046
heart contraction GO:0060047 93 0.046
nucleoside phosphate metabolic process GO:0006753 338 0.045
aromatic compound catabolic process GO:0019439 286 0.045
ribonucleotide metabolic process GO:0009259 291 0.044
ion transmembrane transport GO:0034220 361 0.044
organophosphate catabolic process GO:0046434 232 0.044
muscle adaptation GO:0043500 39 0.043
purine containing compound metabolic process GO:0072521 311 0.043
cellular chemical homeostasis GO:0055082 215 0.042
cellular lipid metabolic process GO:0044255 323 0.042
muscle cell development GO:0055001 133 0.042
l amino acid transport GO:0015807 32 0.042
myeloid cell differentiation GO:0030099 233 0.042
nucleoside triphosphate metabolic process GO:0009141 230 0.041
macromolecule catabolic process GO:0009057 281 0.041
organonitrogen compound catabolic process GO:1901565 264 0.040
actin filament based movement GO:0030048 23 0.040
nucleoside phosphate catabolic process GO:1901292 222 0.039
carboxylic acid transport GO:0046942 100 0.039
organic acid biosynthetic process GO:0016053 86 0.038
blood circulation GO:0008015 195 0.038
heart process GO:0003015 94 0.038
organelle fission GO:0048285 170 0.038
ribose phosphate metabolic process GO:0019693 291 0.038
mitotic cell cycle process GO:1903047 159 0.037
regulation of organelle organization GO:0033043 289 0.037
response to iron ion GO:0010039 4 0.036
nuclear division GO:0000280 158 0.036
protein localization to organelle GO:0033365 185 0.036
erythrocyte differentiation GO:0030218 88 0.036
cellular macromolecule catabolic process GO:0044265 206 0.036
multicellular organismal signaling GO:0035637 91 0.036
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.035
glycosyl compound catabolic process GO:1901658 206 0.035
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.035
purine nucleotide catabolic process GO:0006195 211 0.035
protein modification by small protein conjugation or removal GO:0070647 207 0.035
purine nucleoside catabolic process GO:0006152 205 0.034
ribonucleoside catabolic process GO:0042454 206 0.034
regulation of hemostasis GO:1900046 28 0.034
actomyosin structure organization GO:0031032 56 0.034
regulation of cellular catabolic process GO:0031329 242 0.033
regulation of proteolysis GO:0030162 164 0.033
regulation of ion transport GO:0043269 215 0.033
cytokine production GO:0001816 319 0.033
purine nucleotide metabolic process GO:0006163 302 0.033
purine nucleoside triphosphate metabolic process GO:0009144 226 0.033
regulation of response to wounding GO:1903034 189 0.033
cellular divalent inorganic cation homeostasis GO:0072503 127 0.033
leukocyte proliferation GO:0070661 172 0.032
cardiac muscle contraction GO:0060048 32 0.032
purine ribonucleotide metabolic process GO:0009150 290 0.032
purine nucleoside metabolic process GO:0042278 241 0.032
carbohydrate derivative catabolic process GO:1901136 231 0.032
protein maturation GO:0051604 176 0.032
nucleotide catabolic process GO:0009166 217 0.032
cellular homeostasis GO:0019725 240 0.031
nucleotide metabolic process GO:0009117 332 0.031
posttranscriptional regulation of gene expression GO:0010608 155 0.031
nucleoside metabolic process GO:0009116 246 0.031
actin mediated cell contraction GO:0070252 15 0.030
positive regulation of cellular amine metabolic process GO:0033240 5 0.030
nitrogen compound transport GO:0071705 271 0.030
sequestering of calcium ion GO:0051208 18 0.030
negative regulation of bmp signaling pathway GO:0030514 35 0.030
defense response to other organism GO:0098542 197 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.029
regulation of wound healing GO:0061041 40 0.029
positive regulation of protein modification process GO:0031401 299 0.029
purine containing compound catabolic process GO:0072523 213 0.029
response to oxygen levels GO:0070482 62 0.028
regulation of membrane potential GO:0042391 192 0.028
hemostasis GO:0007599 78 0.028
protein catabolic process GO:0030163 221 0.028
glycosyl compound metabolic process GO:1901657 246 0.028
negative regulation of response to wounding GO:1903035 77 0.028
regulation of bmp signaling pathway GO:0030510 60 0.028
protein modification by small protein conjugation GO:0032446 187 0.028
inorganic cation transmembrane transport GO:0098662 207 0.027
protein ubiquitination GO:0016567 171 0.027
ribonucleoside triphosphate metabolic process GO:0009199 220 0.027
response to organic cyclic compound GO:0014070 198 0.027
cytoplasmic transport GO:0016482 234 0.027
positive regulation of cell activation GO:0050867 158 0.027
immune effector process GO:0002252 321 0.027
regulation of homeostatic process GO:0032844 182 0.026
mitotic cell cycle GO:0000278 195 0.026
regulation of intracellular transport GO:0032386 159 0.026
organic hydroxy compound metabolic process GO:1901615 203 0.026
microtubule based process GO:0007017 236 0.026
cell adhesion GO:0007155 329 0.026
Mouse
ribonucleoside metabolic process GO:0009119 245 0.026
nucleoside triphosphate catabolic process GO:0009143 205 0.025
regulation of purine nucleotide metabolic process GO:1900542 169 0.025
intracellular protein transport GO:0006886 204 0.025
learning or memory GO:0007611 148 0.025
negative regulation of molecular function GO:0044092 258 0.025
zymogen activation GO:0031638 41 0.025
divalent metal ion transport GO:0070838 172 0.025
regulation of cell cycle GO:0051726 281 0.025
ras protein signal transduction GO:0007265 77 0.025
divalent inorganic cation transport GO:0072511 178 0.025
regulation of nucleotide metabolic process GO:0006140 169 0.024
cellular calcium ion homeostasis GO:0006874 119 0.024
amino acid transport GO:0006865 61 0.024
regulation of kinase activity GO:0043549 249 0.024
positive regulation of apoptotic process GO:0043065 217 0.024
heart morphogenesis GO:0003007 178 0.024
fatty acid metabolic process GO:0006631 121 0.024
cellular protein complex assembly GO:0043623 116 0.023
regulation of cell activation GO:0050865 289 0.023
negative regulation of cellular amine metabolic process GO:0033239 1 0.023
ribonucleoside triphosphate catabolic process GO:0009203 199 0.023
lymphocyte proliferation GO:0046651 164 0.023
muscle fiber development GO:0048747 76 0.023
membrane organization GO:0061024 245 0.023
negative regulation of protein metabolic process GO:0051248 282 0.023
rho protein signal transduction GO:0007266 32 0.023
organic anion transport GO:0015711 137 0.023
divalent inorganic cation homeostasis GO:0072507 138 0.023
regulation of protein binding GO:0043393 60 0.023
cellular modified amino acid metabolic process GO:0006575 63 0.023
innate immune response GO:0045087 157 0.023
positive regulation of programmed cell death GO:0043068 218 0.023
regulation of transferase activity GO:0051338 263 0.023
peptidyl amino acid modification GO:0018193 336 0.023
cellular protein catabolic process GO:0044257 155 0.022
cardiac muscle tissue development GO:0048738 130 0.022
reactive nitrogen species metabolic process GO:2001057 0 0.022
regulation of lymphocyte activation GO:0051249 240 0.022
regulation of muscle adaptation GO:0043502 31 0.022
modification dependent protein catabolic process GO:0019941 133 0.022
monocarboxylic acid metabolic process GO:0032787 191 0.022
regulation of nucleotide catabolic process GO:0030811 122 0.022
dna metabolic process GO:0006259 303 0.022
ribonucleotide catabolic process GO:0009261 208 0.022
cellular response to organonitrogen compound GO:0071417 145 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
multicellular organismal homeostasis GO:0048871 164 0.022
coagulation GO:0050817 78 0.022
negative regulation of cellular protein metabolic process GO:0032269 247 0.022
purine nucleoside triphosphate catabolic process GO:0009146 203 0.021
transmission of nerve impulse GO:0019226 76 0.021
purine ribonucleoside catabolic process GO:0046130 205 0.021
developmental maturation GO:0021700 193 0.021
cell recognition GO:0008037 83 0.021
regulation of reactive oxygen species metabolic process GO:2000377 40 0.021
regulation of protein kinase activity GO:0045859 232 0.021
directional locomotion GO:0033058 3 0.021
regulation of purine nucleotide catabolic process GO:0033121 122 0.021
iron ion homeostasis GO:0055072 36 0.021
action potential GO:0001508 78 0.021
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 12 0.021
regulation of cytoskeleton organization GO:0051493 122 0.021
positive regulation of protein phosphorylation GO:0001934 242 0.021
actin filament organization GO:0007015 113 0.021
reactive oxygen species biosynthetic process GO:1903409 8 0.020
regulation of cytokine production GO:0001817 266 0.020
positive regulation of kinase activity GO:0033674 155 0.020
leukocyte differentiation GO:0002521 342 0.020
regulation of nucleoside metabolic process GO:0009118 130 0.020
apoptotic signaling pathway GO:0097190 306 0.020
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.020
regulation of binding GO:0051098 111 0.020
atp metabolic process GO:0046034 75 0.020
spermatogenesis GO:0007283 284 0.020
regulation of secretion GO:0051046 274 0.019
inorganic anion transport GO:0015698 43 0.019
muscle filament sliding GO:0030049 1 0.019
purine ribonucleotide catabolic process GO:0009154 208 0.019
leukocyte activation involved in immune response GO:0002366 126 0.019
regionalization GO:0003002 337 0.019
gland development GO:0048732 330 0.019
atp catabolic process GO:0006200 55 0.019
endocytosis GO:0006897 168 0.019
calcium ion homeostasis GO:0055074 127 0.019
regulation of hormone levels GO:0010817 211 0.019
skeletal system development GO:0001501 356 0.019
negative regulation of intracellular signal transduction GO:1902532 167 0.019
skeletal muscle adaptation GO:0043501 16 0.019
carboxylic acid biosynthetic process GO:0046394 86 0.019
lipid localization GO:0010876 126 0.019
nucleoside catabolic process GO:0009164 206 0.019
purine nucleoside monophosphate catabolic process GO:0009128 58 0.019
small molecule biosynthetic process GO:0044283 132 0.019
regulation of defense response GO:0031347 233 0.019
leukocyte homeostasis GO:0001776 79 0.019
carbohydrate metabolic process GO:0005975 230 0.019
ubiquitin dependent protein catabolic process GO:0006511 129 0.019
positive regulation of protein kinase activity GO:0045860 144 0.018
nucleocytoplasmic transport GO:0006913 139 0.018
modification dependent macromolecule catabolic process GO:0043632 133 0.018
regulation of transmembrane transport GO:0034762 128 0.018
regulation of protein localization GO:0032880 231 0.018
positive regulation of proteolysis GO:0045862 85 0.018
positive regulation of cell death GO:0010942 224 0.018
protein localization to nucleus GO:0034504 121 0.018
actin myosin filament sliding GO:0033275 1 0.018
regulation of secretion by cell GO:1903530 249 0.018
regulation of muscle contraction GO:0006937 49 0.018
reactive oxygen species metabolic process GO:0072593 84 0.018
ribonucleoside monophosphate catabolic process GO:0009158 57 0.018
purine ribonucleoside metabolic process GO:0046128 241 0.018
regulation of skeletal muscle adaptation GO:0014733 12 0.018
cognition GO:0050890 149 0.018
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.018
skeletal muscle organ development GO:0060538 163 0.018
sequestering of metal ion GO:0051238 19 0.018
lymphocyte homeostasis GO:0002260 64 0.017
regulation of cell cycle process GO:0010564 160 0.017
response to oxidative stress GO:0006979 123 0.017
cellular carbohydrate metabolic process GO:0044262 119 0.017
anatomical structure homeostasis GO:0060249 145 0.017
regulation of vesicle mediated transport GO:0060627 139 0.017
regulation of cellular component biogenesis GO:0044087 181 0.017
adaptive immune response GO:0002250 155 0.017
lymphocyte activation involved in immune response GO:0002285 93 0.017
adult behavior GO:0030534 135 0.017
maintenance of location GO:0051235 89 0.017
regulation of cytoplasmic transport GO:1903649 112 0.017
skeletal muscle thin filament assembly GO:0030240 2 0.017
cell maturation GO:0048469 127 0.017
ribonucleoside monophosphate metabolic process GO:0009161 80 0.017
regulation of coagulation GO:0050818 31 0.017
angiogenesis GO:0001525 201 0.017
cardiac muscle cell development GO:0055013 39 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.016
regulation of ion transmembrane transport GO:0034765 119 0.016
chemotaxis GO:0006935 247 0.016
endoplasmic reticulum to cytosol transport GO:1903513 12 0.016
positive regulation of cellular catabolic process GO:0031331 148 0.016
porphyrin containing compound biosynthetic process GO:0006779 16 0.016
response to starvation GO:0042594 65 0.016
alcohol metabolic process GO:0006066 116 0.016
positive regulation of transferase activity GO:0051347 167 0.016
nuclear transport GO:0051169 139 0.016
ear development GO:0043583 200 0.016
ventricular cardiac muscle cell action potential GO:0086005 4 0.016
positive regulation of cell cycle GO:0045787 92 0.016
negative regulation of organelle organization GO:0010639 90 0.016
negative regulation of protein modification process GO:0031400 163 0.016
tetrapyrrole biosynthetic process GO:0033014 16 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.016
cardiac chamber development GO:0003205 108 0.016
regulation of cell motility GO:2000145 236 0.015
microtubule cytoskeleton organization GO:0000226 157 0.015
negative regulation of cell proliferation GO:0008285 296 0.015
regulation of cysteine type endopeptidase activity GO:2000116 65 0.015
response to hypoxia GO:0001666 58 0.015
locomotory behavior GO:0007626 195 0.015
regulation of heart contraction GO:0008016 77 0.015
tissue homeostasis GO:0001894 115 0.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.015
segmentation GO:0035282 93 0.015
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.015
sensory perception GO:0007600 245 0.015
negative regulation of homeostatic process GO:0032845 71 0.015
negative regulation of cellular component organization GO:0051129 194 0.015
response to lipopolysaccharide GO:0032496 128 0.015
regulation of feeding behavior GO:0060259 3 0.015
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.015
cell division GO:0051301 120 0.015
regulation of sarcomere organization GO:0060297 4 0.015
cellular response to organic cyclic compound GO:0071407 87 0.015
cellular response to hormone stimulus GO:0032870 150 0.015
cellular alcohol biosynthetic process GO:0044108 3 0.015
regulation of peptidase activity GO:0052547 96 0.015
cellular response to lipid GO:0071396 145 0.015
positive regulation of cytokine production GO:0001819 174 0.015
sa node cell action potential GO:0086015 4 0.015
t cell proliferation GO:0042098 120 0.015
cardiac muscle fiber development GO:0048739 4 0.015
response to muscle inactivity GO:0014870 4 0.014
release of sequestered calcium ion into cytosol GO:0051209 42 0.014
detection of stimulus GO:0051606 84 0.014
organophosphate biosynthetic process GO:0090407 122 0.014
positive regulation of lymphocyte activation GO:0051251 140 0.014
axonogenesis GO:0007409 274 0.014
regulation of protein stability GO:0031647 52 0.014
leukocyte mediated immunity GO:0002443 174 0.014
positive regulation of hydrolase activity GO:0051345 148 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.014
nucleoside monophosphate catabolic process GO:0009125 59 0.014
sensory perception of mechanical stimulus GO:0050954 107 0.014
oocyte construction GO:0007308 2 0.014
skin development GO:0043588 220 0.014
tissue remodeling GO:0048771 102 0.014
mapk cascade GO:0000165 281 0.014
regulation of cell projection organization GO:0031344 206 0.014
nuclear import GO:0051170 95 0.014
cell activation involved in immune response GO:0002263 126 0.014
regulation of mitotic cell cycle GO:0007346 126 0.014
cardiac muscle cell contraction GO:0086003 7 0.014
response to acid chemical GO:0001101 111 0.013
small gtpase mediated signal transduction GO:0007264 97 0.013
regulation of ion transmembrane transporter activity GO:0032412 54 0.013
response to molecule of bacterial origin GO:0002237 143 0.013
regulation of skeletal muscle contraction GO:0014819 3 0.013
cilium morphogenesis GO:0060271 102 0.013
regulation of protein catabolic process GO:0042176 108 0.013
regulation of blood pressure GO:0008217 93 0.013
regulation of actin cytoskeleton organization GO:0032956 84 0.013
pigment metabolic process GO:0042440 32 0.013
regulation of mapk cascade GO:0043408 248 0.013
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.013
ossification GO:0001503 216 0.013
carbohydrate derivative biosynthetic process GO:1901137 183 0.013
negative regulation of coagulation GO:0050819 11 0.013
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 12 0.013
regulation of atp metabolic process GO:1903578 17 0.013
myofibril assembly GO:0030239 34 0.013
calcium ion transmembrane transport GO:0070588 85 0.013
intrinsic apoptotic signaling pathway GO:0097193 132 0.013
protein glycosylation GO:0006486 55 0.013
response to metal ion GO:0010038 47 0.013
fertilization GO:0009566 127 0.013
regulation of anatomical structure size GO:0090066 178 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.013
establishment of blood nerve barrier GO:0008065 3 0.013
regulation of inflammatory response GO:0050727 147 0.013
relaxation of muscle GO:0090075 18 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
endomembrane system organization GO:0010256 147 0.013
positive regulation of binding GO:0051099 49 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
positive regulation of mitochondrial calcium ion concentration GO:0051561 3 0.013
meiotic cell cycle GO:0051321 122 0.013
regulation of blood coagulation GO:0030193 28 0.012
positive regulation of protein binding GO:0032092 29 0.012
cytokinetic process GO:0032506 2 0.012
wnt signaling pathway GO:0016055 188 0.012
regulation of ph GO:0006885 26 0.012
lymphocyte differentiation GO:0030098 242 0.012
regulation of apoptotic signaling pathway GO:2001233 197 0.012
regulation of cellular component size GO:0032535 121 0.012
negative regulation of protein complex disassembly GO:0043242 22 0.012
skeletal muscle myosin thick filament assembly GO:0030241 1 0.012
rna interference GO:0016246 2 0.012
cell type specific apoptotic process GO:0097285 268 0.012
cardiac muscle cell differentiation GO:0055007 69 0.012
positive regulation of cell cycle process GO:0090068 61 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
carboxylic acid catabolic process GO:0046395 51 0.012
single organism nuclear import GO:1902593 95 0.012
cellular alcohol metabolic process GO:0044107 3 0.012
hydrogen ion transmembrane transport GO:1902600 25 0.012
neuron maturation GO:0042551 29 0.012
developmental growth involved in morphogenesis GO:0060560 138 0.012
single organism cell adhesion GO:0098602 156 0.012
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 10 0.012
response to inactivity GO:0014854 4 0.012
negative regulation of cytokine production GO:0001818 84 0.012
regulation of body fluid levels GO:0050878 162 0.012
response to muscle stretch GO:0035994 1 0.012
cilium assembly GO:0042384 81 0.012
regulation of cell shape GO:0008360 39 0.012
oocyte axis specification GO:0007309 2 0.012
renal system development GO:0072001 225 0.012
maternal determination of anterior posterior axis embryo GO:0008358 2 0.012
synaptic transmission GO:0007268 329 0.012
glycerolipid metabolic process GO:0046486 122 0.012
detection of external stimulus GO:0009581 61 0.012
multi multicellular organism process GO:0044706 109 0.012
response to organonitrogen compound GO:0010243 246 0.012
male gamete generation GO:0048232 285 0.012
germ cell development GO:0007281 185 0.012
response to inorganic substance GO:0010035 96 0.012
stem cell differentiation GO:0048863 268 0.012
dephosphorylation GO:0016311 129 0.012
canonical wnt signaling pathway GO:0060070 130 0.011
transition between fast and slow fiber GO:0014883 9 0.011
regulation of transporter activity GO:0032409 57 0.011
skeletal muscle cell differentiation GO:0035914 66 0.011
small molecule catabolic process GO:0044282 71 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
actin polymerization or depolymerization GO:0008154 54 0.011
positive regulation of defense response GO:0031349 124 0.011
plasma membrane organization GO:0007009 90 0.011
glycosylation GO:0070085 62 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
regulation of multi organism process GO:0043900 111 0.011
hormone metabolic process GO:0042445 86 0.011
actin filament polymerization GO:0030041 44 0.011
macrophage activation GO:0042116 27 0.011
glycoprotein biosynthetic process GO:0009101 89 0.011
meiotic cell cycle process GO:1903046 77 0.011
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
t cell activation involved in immune response GO:0002286 43 0.011
mitochondrion organization GO:0007005 134 0.011
epithelial cell development GO:0002064 159 0.011
chromatin modification GO:0016568 187 0.011
sensory organ morphogenesis GO:0090596 242 0.011
forebrain development GO:0030900 302 0.011
body morphogenesis GO:0010171 45 0.011
somite development GO:0061053 81 0.011
Zebrafish
regulation of lymphocyte proliferation GO:0050670 117 0.011
intracellular mrna localization GO:0008298 4 0.011
glycoprotein metabolic process GO:0009100 116 0.011
engulfment of apoptotic cell GO:0043652 3 0.011
positive regulation of organelle organization GO:0010638 128 0.011
proteasomal protein catabolic process GO:0010498 98 0.011
monocarboxylic acid biosynthetic process GO:0072330 61 0.011
regulation of leukocyte proliferation GO:0070663 121 0.011
mitotic nuclear division GO:0007067 48 0.011
sensory perception of sound GO:0007605 97 0.011
negative regulation of hemostasis GO:1900047 11 0.011
urogenital system development GO:0001655 261 0.011
lipid homeostasis GO:0055088 63 0.011
regulation of t cell proliferation GO:0042129 92 0.011
substantia nigra development GO:0021762 2 0.011
organelle localization GO:0051640 179 0.011
regulation of interleukin 8 production GO:0032677 3 0.011
regulation of organ morphogenesis GO:2000027 144 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
negative regulation of cell development GO:0010721 169 0.011
protein polymerization GO:0051258 57 0.011
positive regulation of cell development GO:0010720 237 0.011
energy derivation by oxidation of organic compounds GO:0015980 77 0.011
positive regulation of lymphocyte proliferation GO:0050671 70 0.011

Hfe2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 0 0.343
disease of anatomical entity DOID:7 0 0.343
musculoskeletal system disease DOID:17 0 0.343
muscle tissue disease DOID:66 0 0.343
myopathy DOID:423 0 0.158
heart disease DOID:114 0 0.158
cardiomyopathy DOID:0050700 0 0.158
cardiovascular system disease DOID:1287 0 0.158
intrinsic cardiomyopathy DOID:0060036 0 0.114
immune system disease DOID:2914 0 0.108
anemia DOID:2355 0 0.108
hematopoietic system disease DOID:74 0 0.108
hypertrophic cardiomyopathy DOID:11984 0 0.036
nervous system disease DOID:863 0 0.036
dilated cardiomyopathy DOID:12930 0 0.025
disease of metabolism DOID:0014667 0 0.021
inherited metabolic disorder DOID:655 0 0.020
muscular dystrophy DOID:9884 0 0.013
central nervous system disease DOID:331 0 0.013
neurodegenerative disease DOID:1289 0 0.011