IMP

Process View

Mus musculus

16 genes annotated in mouse

skeletal muscle adaptation

Any process in which skeletal muscles change their phenotypic profiles in response to altered functional demands and a variety of signals.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "skeletal muscle adaptation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "skeletal muscle adaptation" (in gray)

Name	Description	Probability	Func Analog Organism
Tnni2	troponin I, skeletal, fast 2	0.993	Mouse
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.977
Hrc	histidine rich calcium binding protein	0.935
Tnnt3	troponin T3, skeletal, fast	0.854	Mouse
Actn2	actinin alpha 2	0.845
Ldb3	LIM domain binding 3	0.703
Trim55	tripartite motif-containing 55	0.600
Myoz1	myozenin 1	0.586
Tnnt2	troponin T2, cardiac	0.562
Tnnc2	troponin C2, fast	0.541	Mouse
Ryr1	ryanodine receptor 1, skeletal muscle	0.529
Myom2	myomesin 2	0.518
Mybph	myosin binding protein H	0.513
Cacna1s	calcium channel, voltage-dependent, L type, alpha 1S subunit	0.493
Atp2a1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	0.488	Mouse
Casq2	calsequestrin 2	0.444
Actc1	actin, alpha, cardiac muscle 1	0.438
Casq1	calsequestrin 1	0.409
Actn3	actinin alpha 3	0.400
Ckmt2	creatine kinase, mitochondrial 2	0.344
Pgam2	phosphoglycerate mutase 2	0.339
Tcap	titin-cap	0.310
Csrp3	cysteine and glycine-rich protein 3	0.302
Myl1	myosin, light polypeptide 1	0.247
Mylpf	myosin light chain, phosphorylatable, fast skeletal muscle	0.239
Nfatc3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	0.234	Mouse
Cav3	caveolin 3	0.223
Myh8	myosin, heavy polypeptide 8, skeletal muscle, perinatal	0.220
Yap1	yes-associated protein 1	0.207
Chrna1	cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)	0.201
Myh1	myosin, heavy polypeptide 1, skeletal muscle, adult	0.191	Mouse
Cacng1	calcium channel, voltage-dependent, gamma subunit 1	0.185
Myh3	myosin, heavy polypeptide 3, skeletal muscle, embryonic	0.183
Myom1	myomesin 1	0.172
Cox8b	cytochrome c oxidase, subunit VIIIb	0.158
Myf6	myogenic factor 6	0.155	Mouse
Xirp1	xin actin-binding repeat containing 1	0.148
Hspb2	heat shock protein 2	0.147
Apobec2	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2	0.117
Nrap	nebulin-related anchoring protein	0.117
Gtf2ird1	general transcription factor II I repeat domain-containing 1	0.115
Myl3	myosin, light polypeptide 3	0.112
Cox6a2	cytochrome c oxidase, subunit VI a, polypeptide 2	0.095
Myh4	myosin, heavy polypeptide 4, skeletal muscle	0.093	Mouse
Myh2	myosin, heavy polypeptide 2, skeletal muscle, adult	0.090
Myh7	myosin, heavy polypeptide 7, cardiac muscle, beta	0.089
Prkce	protein kinase C, epsilon	0.089
Ckm	creatine kinase, muscle	0.084
Tnnc1	troponin C, cardiac/slow skeletal	0.081
Kbtbd5	kelch repeat and BTB (POZ) domain containing 5	0.080
Ppp3r1	protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)	0.073
Kcnma1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	0.072
Pvalb	parvalbumin	0.071
Pax7	paired box gene 7	0.071
Myf5	myogenic factor 5	0.068	Mouse
Ttn	titin	0.066
Ankrd2	ankyrin repeat domain 2 (stretch responsive muscle)	0.065
Sgcg	sarcoglycan, gamma (dystrophin-associated glycoprotein)	0.063
Lmod2	leiomodin 2 (cardiac)	0.062
Pitx2	paired-like homeodomain transcription factor 2	0.061
Srpk3	serine/arginine-rich protein specific kinase 3	0.060
Art1	ADP-ribosyltransferase 1	0.058
Tnnt1	troponin T1, skeletal, slow	0.053
Col17a1	collagen, type XVII, alpha 1	0.050
Myog	myogenin	0.049	Mouse
Trim54	tripartite motif-containing 54	0.048
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.045
Myot	myotilin	0.044
Cacnb2	calcium channel, voltage-dependent, beta 2 subunit	0.044
Itch	itchy, E3 ubiquitin protein ligase	0.043
Myl7	myosin, light polypeptide 7, regulatory	0.043
Acta1	actin, alpha 1, skeletal muscle	0.043	Rat
Tnni1	troponin I, skeletal, slow 1	0.043
Slc17a8	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8	0.043
Pitx1	paired-like homeodomain transcription factor 1	0.042
Mas1	MAS1 oncogene	0.040
Des	desmin	0.036
Wfikkn2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.036
Tcf15	transcription factor 15	0.036
Gtf2i	general transcription factor II I	0.035
Pygm	muscle glycogen phosphorylase	0.034
Krt15	keratin 15	0.031
Tbx15	T-box 15	0.030
Cdh15	cadherin 15	0.029
Mpz	myelin protein zero	0.028
Map3k5	mitogen-activated protein kinase kinase kinase 5	0.027
Myl4	myosin, light polypeptide 4	0.027
Dlk1	delta-like 1 homolog (Drosophila)	0.027
Phkg1	phosphorylase kinase gamma 1	0.027
Dkk2	dickkopf homolog 2 (Xenopus laevis)	0.026
Myoz2	myozenin 2	0.026
Cacnb4	calcium channel, voltage-dependent, beta 4 subunit	0.025
Wwtr1	WW domain containing transcription regulator 1	0.025
Itgb1bp2	integrin beta 1 binding protein 2	0.025
Ucp3	uncoupling protein 3 (mitochondrial, proton carrier)	0.024
Crhr2	corticotropin releasing hormone receptor 2	0.024
Mybpc1	myosin binding protein C, slow-type	0.024
Popdc3	popeye domain containing 3	0.023
Smpx	small muscle protein, X-linked	0.023
Trim63	tripartite motif-containing 63	0.022	Rat
Rapsn	receptor-associated protein of the synapse	0.022
Bsn	bassoon	0.022
Shox2	short stature homeobox 2	0.022
Mll2	myeloid/lymphoid or mixed-lineage leukemia 2	0.022
Fbxo32	F-box protein 32	0.022
Nfatc4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	0.021	Mouse
Slco5a1	solute carrier organic anion transporter family, member 5A1	0.021
Eef1a2	eukaryotic translation elongation factor 1 alpha 2	0.021
Flnc	filamin C, gamma	0.021
Cacnb3	calcium channel, voltage-dependent, beta 3 subunit	0.021
Art5	ADP-ribosyltransferase 5	0.020
Mdm4	transformed mouse 3T3 cell double minute 4	0.020
Tpm2	tropomyosin 2, beta	0.020
Sh3bgr	SH3-binding domain glutamic acid-rich protein	0.020
Serpinb5	serine (or cysteine) peptidase inhibitor, clade B, member 5	0.020
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.019
Nos1	nitric oxide synthase 1, neuronal	0.019
Gdpd5	glycerophosphodiester phosphodiesterase domain containing 5	0.019
Kcnj3	potassium inwardly-rectifying channel, subfamily J, member 3	0.019
Hfe2	hemochromatosis type 2 (juvenile) (human homolog)	0.019
Sgca	sarcoglycan, alpha (dystrophin-associated glycoprotein)	0.019
Notch4	Notch gene homolog 4 (Drosophila)	0.018
Trdn	triadin	0.018
Il16	interleukin 16	0.018
Prkd2	protein kinase D2	0.018
Ski	ski sarcoma viral oncogene homolog (avian)	0.018
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.018
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.018
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.018
Il12a	interleukin 12a	0.018
Mef2a	myocyte enhancer factor 2A	0.018
Myom3	myomesin family, member 3	0.017
Fgf18	fibroblast growth factor 18	0.017
Peg10	paternally expressed 10	0.017
Rpl3l	ribosomal protein L3-like	0.017
Gabrb3	gamma-aminobutyric acid (GABA) A receptor, subunit beta 3	0.017
Camk2a	calcium/calmodulin-dependent protein kinase II alpha	0.016
U46068	cDNA sequence U46068	0.016
Akap5	A kinase (PRKA) anchor protein 5	0.016
Myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	0.016	Mouse
Txlnb	taxilin beta	0.016
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.016
P2rx6	purinergic receptor P2X, ligand-gated ion channel, 6	0.016
Pnliprp2	pancreatic lipase-related protein 2	0.016
Hhat	hedgehog acyltransferase	0.016
Stx1a	syntaxin 1A (brain)	0.016
Fgf13	fibroblast growth factor 13	0.015
Rtn2	reticulon 2 (Z-band associated protein)	0.015
Stac3	SH3 and cysteine rich domain 3	0.015
Creb1	cAMP responsive element binding protein 1	0.015
Sln	sarcolipin	0.015
Lmod3	leiomodin 3 (fetal)	0.015
Mt4	metallothionein 4	0.015
Fbn2	fibrillin 2	0.015
Kcnj2	potassium inwardly-rectifying channel, subfamily J, member 2	0.015
Mb	myoglobin	0.014
Tulp1	tubby like protein 1	0.014
Rrad	Ras-related associated with diabetes	0.014
Ids	iduronate 2-sulfatase	0.014
Scgb1a1	secretoglobin, family 1A, member 1 (uteroglobin)	0.014
Vgll2	vestigial like 2 homolog (Drosophila)	0.013
Ankrd1	ankyrin repeat domain 1 (cardiac muscle)	0.013
Ebf2	early B-cell factor 2	0.013
Mecom	MDS1 and EVI1 complex locus	0.012
Cox7a1	cytochrome c oxidase, subunit VIIa 1	0.012
Mybpc3	myosin binding protein C, cardiac	0.012
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.012
Hspb7	heat shock protein family, member 7 (cardiovascular)	0.012
Tuba8	tubulin, alpha 8	0.012
Murc	muscle-related coiled-coil protein	0.012
Wnt11	wingless-related MMTV integration site 11	0.012
Synpo2l	synaptopodin 2-like	0.012
Msc	musculin	0.012
Capn3	calpain 3	0.012
Dhh	desert hedgehog	0.011
Chrnb1	cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)	0.011
Mstn	myostatin	0.011	Rat
Zmynd11	zinc finger, MYND domain containing 11	0.011
Ank1	ankyrin 1, erythroid	0.011
Alpk3	alpha-kinase 3	0.011
Crb2	crumbs homolog 2 (Drosophila)	0.011
Pdlim3	PDZ and LIM domain 3	0.011
Rasgrf2	RAS protein-specific guanine nucleotide-releasing factor 2	0.011
Igbp1	immunoglobulin (CD79A) binding protein 1	0.011
Map2k4	mitogen-activated protein kinase kinase 4	0.011
Bglap	bone gamma carboxyglutamate protein	0.011
Adcy4	adenylate cyclase 4	0.010
Krtap3-3	keratin associated protein 3-3	0.010
Atoh7	atonal homolog 7 (Drosophila)	0.010
Adipoq	adiponectin, C1Q and collagen domain containing	0.010
Tmod4	tropomodulin 4	0.010
Myod1	myogenic differentiation 1	0.010
Mlf1	myeloid leukemia factor 1	0.010
Fndc7	fibronectin type III domain containing 7	0.010
Fgf7	fibroblast growth factor 7	0.010
Spry4	sprouty homolog 4 (Drosophila)	0.010
Tnni3	troponin I, cardiac 3	0.010	Mouse