Mus musculus

141 known processes

Hes3

hairy and enhancer of split 3 (Drosophila)

(Aliases: MGC144657,bHLHb43,Hes-3)

Hes3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
forebrain development GO:0030900 302 0.814
Mouse
cellular amino acid metabolic process GO:0006520 103 0.772
midbrain hindbrain boundary morphogenesis GO:0021555 4 0.704
striated muscle tissue development GO:0014706 293 0.693
gland development GO:0048732 330 0.642
Mouse
bmp signaling pathway GO:0030509 93 0.627
Mouse
auditory receptor cell fate determination GO:0042668 3 0.606
Mouse
embryonic organ morphogenesis GO:0048562 276 0.606
Mouse
regulation of membrane potential GO:0042391 192 0.593
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.583
cell fate commitment GO:0045165 210 0.581
Mouse Worm Fly
camera type eye development GO:0043010 266 0.549
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.549
axonogenesis GO:0007409 274 0.541
regulation of neuron projection development GO:0010975 169 0.513
regionalization GO:0003002 337 0.506
oculomotor nerve development GO:0021557 4 0.501
appendage development GO:0048736 166 0.493
metencephalon development GO:0022037 89 0.485
stem cell differentiation GO:0048863 268 0.463
Mouse
stem cell development GO:0048864 219 0.434
Mouse
neuron fate specification GO:0048665 30 0.430
neuron projection guidance GO:0097485 141 0.428
locomotory behavior GO:0007626 195 0.421
Fly
chemotaxis GO:0006935 247 0.399
cell fate determination involved in pattern specification GO:0060582 1 0.397
Fly
limbic system development GO:0021761 72 0.397
t cell proliferation GO:0042098 120 0.396
Mouse
negative regulation of pancreatic a cell differentiation GO:2000227 1 0.383
Mouse
positive regulation of bmp signaling pathway GO:0030513 23 0.382
Mouse
positive regulation of cell development GO:0010720 237 0.379
Mouse Fly
endocrine pancreas development GO:0031018 29 0.378
Mouse
epithelial cell development GO:0002064 159 0.374
heart morphogenesis GO:0003007 178 0.367
Mouse
nephron epithelium morphogenesis GO:0072088 68 0.366
Mouse
leukocyte proliferation GO:0070661 172 0.362
Mouse
embryonic heart tube morphogenesis GO:0003143 51 0.355
Mouse
stem cell proliferation GO:0072089 117 0.354
Fly
sensory organ boundary specification GO:0008052 1 0.349
Fly
kidney epithelium development GO:0072073 121 0.345
Mouse
nerve development GO:0021675 67 0.336
metanephric nephron development GO:0072210 34 0.334
Mouse
amine metabolic process GO:0009308 45 0.333
skeletal system development GO:0001501 356 0.330
Mouse
regulation of organ morphogenesis GO:2000027 144 0.327
Mouse
central nervous system neuron differentiation GO:0021953 162 0.324
brain morphogenesis GO:0048854 32 0.324
Fly
ventral spinal cord interneuron fate commitment GO:0060579 14 0.323
inner ear receptor cell differentiation GO:0060113 61 0.323
Mouse
positive regulation of nervous system development GO:0051962 221 0.320
Mouse Fly
pallium development GO:0021543 120 0.320
regulation of bmp signaling pathway GO:0030510 60 0.320
Mouse
regulation of cell cycle GO:0051726 281 0.319
Mouse
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.313
Mouse
regulation of neuron differentiation GO:0045664 281 0.312
hindbrain morphogenesis GO:0021575 46 0.311
regulation of neuron apoptotic process GO:0043523 122 0.309
stomach neuroendocrine cell differentiation GO:0061102 2 0.304
Mouse
trochlear nerve development GO:0021558 3 0.301
specification of nephron tubule identity GO:0072081 5 0.295
Mouse
cerebral cortex radially oriented cell migration GO:0021799 31 0.292
synaptic transmission GO:0007268 329 0.290
hindbrain development GO:0030902 128 0.280
telencephalon development GO:0021537 186 0.277
Mouse
cellular amine metabolic process GO:0044106 44 0.273
segmentation GO:0035282 93 0.268
Mouse
formation of organ boundary GO:0010160 1 0.265
Fly
placenta development GO:0001890 140 0.262
Mouse
labyrinthine layer blood vessel development GO:0060716 21 0.260
Mouse
embryonic heart tube development GO:0035050 65 0.256
Mouse
positive regulation of neuron differentiation GO:0045666 141 0.249
neural tube development GO:0021915 160 0.248
membrane organization GO:0061024 245 0.247
epithelial tube formation GO:0072175 130 0.242
Mouse
negative regulation of stomach neuroendocrine cell differentiation GO:0061106 1 0.241
Mouse
somitogenesis GO:0001756 69 0.239
Mouse
somatotropin secreting cell differentiation GO:0060126 4 0.237
digestive system development GO:0055123 200 0.234
Mouse
myelination GO:0042552 74 0.231
Mouse
cell maturation GO:0048469 127 0.227
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.213
Mouse
ureteric bud morphogenesis GO:0060675 62 0.209
Mouse
nephron development GO:0072006 109 0.206
Mouse
pancreatic pp cell fate commitment GO:0003329 2 0.206
segment specification GO:0007379 15 0.203
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.196
cerebellum development GO:0021549 77 0.196
brain segmentation GO:0035284 3 0.196
cerebral cortex cell migration GO:0021795 44 0.194
diencephalon development GO:0021536 63 0.193
Mouse
tyrosine phosphorylation of stat3 protein GO:0042503 12 0.192
Mouse
cardiac chamber morphogenesis GO:0003206 93 0.192
Mouse
oligodendrocyte development GO:0014003 20 0.192
Mouse
cell fate specification GO:0001708 72 0.192
Worm
appendage morphogenesis GO:0035107 149 0.192
regulation of timing of neuron differentiation GO:0060164 5 0.192
regulation of stomach neuroendocrine cell differentiation GO:0061105 1 0.191
Mouse
developmental maturation GO:0021700 193 0.191
Mouse
mechanoreceptor differentiation GO:0042490 67 0.190
Mouse
cerebellum morphogenesis GO:0021587 42 0.189
cerebellar purkinje cell layer morphogenesis GO:0021692 14 0.188
myeloid cell differentiation GO:0030099 233 0.187
midbrain development GO:0030901 35 0.185
axon guidance GO:0007411 141 0.185
regulation of mitotic cell cycle GO:0007346 126 0.182
Mouse
carboxylic acid biosynthetic process GO:0046394 86 0.180
organic acid biosynthetic process GO:0016053 86 0.173
respiratory tube development GO:0030323 167 0.171
Mouse
spinal cord development GO:0021510 81 0.170
ascending aorta morphogenesis GO:0035910 3 0.168
Mouse
sensory perception GO:0007600 245 0.167
germ cell development GO:0007281 185 0.165
glial cell differentiation GO:0010001 131 0.164
Mouse
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.161
adenohypophysis development GO:0021984 14 0.161
Mouse
peripheral nervous system neuron axonogenesis GO:0048936 3 0.160
cellular ketone metabolic process GO:0042180 84 0.159
regulation of t cell activation GO:0050863 170 0.157
Mouse
negative regulation of stem cell differentiation GO:2000737 14 0.157
embryonic placenta development GO:0001892 98 0.156
Mouse
sensory organ morphogenesis GO:0090596 242 0.156
Fly
pancreatic pp cell differentiation GO:0003312 2 0.153
synapse organization GO:0050808 125 0.150
peripheral nervous system development GO:0007422 53 0.149
hypophysis morphogenesis GO:0048850 3 0.149
forebrain morphogenesis GO:0048853 17 0.149
gastrulation GO:0007369 116 0.148
telencephalon cell migration GO:0022029 55 0.145
endocrine system development GO:0035270 98 0.144
Mouse
glomerulus development GO:0032835 40 0.143
Mouse
hypothalamus development GO:0021854 16 0.142
development of primary sexual characteristics GO:0045137 143 0.138
outflow tract morphogenesis GO:0003151 53 0.137
Mouse
negative regulation of neuron differentiation GO:0045665 101 0.137
Mouse
lung development GO:0030324 164 0.136
Mouse
chromatin modification GO:0016568 187 0.135
cerebellar cortex development GO:0021695 48 0.135
neuron apoptotic process GO:0051402 142 0.134
chromatin organization GO:0006325 206 0.134
neuromuscular process GO:0050905 99 0.133
Fly
limb morphogenesis GO:0035108 149 0.133
cerebellar cortex formation GO:0021697 22 0.132
forebrain neuron development GO:0021884 30 0.132
nephron tubule morphogenesis GO:0072078 68 0.130
Mouse
labyrinthine layer development GO:0060711 49 0.129
Mouse
neuron projection extension GO:1990138 64 0.129
small molecule biosynthetic process GO:0044283 132 0.128
ventral spinal cord interneuron differentiation GO:0021514 16 0.128
positive regulation of cell cycle GO:0045787 92 0.127
Mouse
lymphocyte proliferation GO:0046651 164 0.127
Mouse
cell differentiation in hindbrain GO:0021533 24 0.125
cerebral cortex development GO:0021987 86 0.125
paraxial mesodermal cell differentiation GO:0048342 2 0.124
neuronal action potential GO:0019228 54 0.123
Mouse
negative regulation of cell proliferation GO:0008285 296 0.122
Mouse
peptidyl tyrosine modification GO:0018212 145 0.121
Mouse
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.121
monocarboxylic acid metabolic process GO:0032787 191 0.120
divalent inorganic cation transport GO:0072511 178 0.120
ear development GO:0043583 200 0.119
Mouse
organelle fission GO:0048285 170 0.119
embryonic skeletal system development GO:0048706 120 0.116
regulation of cardioblast differentiation GO:0051890 3 0.116
regulation of auditory receptor cell differentiation GO:0045607 4 0.115
Mouse
dendrite development GO:0016358 115 0.115
Fly
neural precursor cell proliferation GO:0061351 121 0.114
Fly
protein import into nucleus GO:0006606 95 0.114
Mouse
neuroblast proliferation GO:0007405 49 0.113
Fly
forebrain neuron differentiation GO:0021879 52 0.113
mesoderm development GO:0007498 100 0.113
Fly
morphogenesis of embryonic epithelium GO:0016331 159 0.113
Mouse
paraxial mesodermal cell fate commitment GO:0048343 2 0.111
central nervous system segmentation GO:0035283 3 0.111
regulation of t cell proliferation GO:0042129 92 0.110
Mouse
cerebellar cortex morphogenesis GO:0021696 32 0.109
neuroblast differentiation GO:0014016 2 0.109
positive regulation of transcription via serum response element binding GO:0010735 1 0.107
transmission of nerve impulse GO:0019226 76 0.107
Mouse
cardiac cell fate determination GO:0060913 2 0.106
skeletal system morphogenesis GO:0048705 203 0.106
developmental cell growth GO:0048588 84 0.105
transmembrane transport GO:0055085 412 0.104
positive regulation of mitotic cell cycle embryonic GO:0045977 2 0.104
Mouse
regulation of intracellular transport GO:0032386 159 0.103
t cell activation GO:0042110 289 0.102
Mouse
positive regulation of neuroblast proliferation GO:0002052 19 0.101
Fly
fatty acid metabolic process GO:0006631 121 0.101
negative regulation of cell development GO:0010721 169 0.101
Mouse
developmental programmed cell death GO:0010623 41 0.100
cell differentiation in spinal cord GO:0021515 53 0.100
ventral spinal cord interneuron specification GO:0021521 11 0.099
action potential GO:0001508 78 0.098
Mouse
regulation of synaptic plasticity GO:0048167 87 0.098
mesonephros development GO:0001823 97 0.098
Mouse
motor neuron migration GO:0097475 4 0.097
nephron morphogenesis GO:0072028 69 0.096
Mouse
placenta blood vessel development GO:0060674 31 0.095
Mouse
cerebellar purkinje cell layer development GO:0021680 26 0.095
negative regulation of protein metabolic process GO:0051248 282 0.094
regulation of secretion GO:0051046 274 0.094
developmental growth involved in morphogenesis GO:0060560 138 0.094
regulation of neuron death GO:1901214 134 0.093
neuroepithelial cell differentiation GO:0060563 37 0.093
Mouse
ventral spinal cord development GO:0021517 48 0.092
negative regulation of cell fate specification GO:0009996 4 0.092
cell proliferation in forebrain GO:0021846 30 0.091
astrocyte fate commitment GO:0060018 4 0.091
regulation of ion transport GO:0043269 215 0.091
regulation of organ growth GO:0046620 61 0.091
renal system development GO:0072001 225 0.090
Mouse
glial cell fate commitment GO:0021781 14 0.090
Mouse
cell adhesion GO:0007155 329 0.089
Mouse
multicellular organism growth GO:0035264 161 0.088
cardiac ventricle morphogenesis GO:0003208 50 0.088
specification of loop of henle identity GO:0072086 4 0.086
Mouse
neural tube formation GO:0001841 108 0.086
sa node cell action potential GO:0086015 4 0.085
lymphocyte differentiation GO:0030098 242 0.085
cardiac epithelial to mesenchymal transition GO:0060317 18 0.084
endodermal cell fate specification GO:0001714 4 0.083
pituitary gland development GO:0021983 38 0.082
Mouse
retinal ganglion cell axon guidance GO:0031290 18 0.082
oviduct development GO:0060066 3 0.082
spermatogenesis GO:0007283 284 0.081
leukocyte differentiation GO:0002521 342 0.081
cell recognition GO:0008037 83 0.081
mesenchymal cell development GO:0014031 93 0.080
Mouse
cell fate commitment involved in pattern specification GO:0060581 14 0.080
Fly
neuron fate determination GO:0048664 9 0.080
Mouse
kidney development GO:0001822 213 0.080
Mouse
b cell differentiation GO:0030183 78 0.079
cytoplasmic transport GO:0016482 234 0.079
Mouse
regulation of cell activation GO:0050865 289 0.079
Mouse
regulation of stem cell differentiation GO:2000736 50 0.079
globus pallidus development GO:0021759 2 0.079
leydig cell differentiation GO:0033327 10 0.079
morphogenesis of a branching epithelium GO:0061138 193 0.078
regulation of homeostatic process GO:0032844 182 0.078
negative regulation of neuron death GO:1901215 98 0.078
neurohypophysis development GO:0021985 2 0.077
hippocampus development GO:0021766 52 0.077
axon ensheathment GO:0008366 76 0.076
Mouse
regulation of cell division GO:0051302 76 0.076
formation of primary germ layer GO:0001704 77 0.076
connective tissue development GO:0061448 179 0.076
Mouse
regulation of heart morphogenesis GO:2000826 22 0.076
Mouse
regulation of neuroblast proliferation GO:1902692 27 0.076
Fly
cardiac ventricle development GO:0003231 83 0.076
Mouse
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.075
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.075
forebrain generation of neurons GO:0021872 63 0.075
neuron death GO:0070997 154 0.075
smoothened signaling pathway GO:0007224 105 0.073
Mouse
regulation of jak stat cascade GO:0046425 34 0.073
Mouse
mesenchyme development GO:0060485 152 0.073
Mouse
rhythmic process GO:0048511 174 0.073
Mouse
motor neuron axon guidance GO:0008045 26 0.073
epidermis development GO:0008544 187 0.073
Mouse Worm
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.073
ossification GO:0001503 216 0.072
neural tube patterning GO:0021532 43 0.072
cell differentiation involved in kidney development GO:0061005 33 0.072
Mouse
negative regulation of nervous system development GO:0051961 156 0.071
Mouse
regulation of secretion by cell GO:1903530 249 0.071
positive regulation of notch signaling pathway GO:0045747 18 0.071
Mouse
auditory receptor cell fate specification GO:0042667 1 0.071
male sex differentiation GO:0046661 109 0.070
Worm
positive regulation of organelle organization GO:0010638 128 0.070
pancreatic a cell fate commitment GO:0003326 2 0.070
metanephros development GO:0001656 79 0.070
Mouse
negative regulation of neuron apoptotic process GO:0043524 92 0.068
metanephric dct cell differentiation GO:0072240 3 0.068
cytokine production GO:0001816 319 0.068
calcium ion transport GO:0006816 159 0.068
epithelial cell fate commitment GO:0072148 13 0.067
Mouse
epithelial tube morphogenesis GO:0060562 303 0.067
Mouse
somatotropin secreting cell development GO:0060133 2 0.067
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.067
retina development in camera type eye GO:0060041 119 0.067
digestive tract morphogenesis GO:0048546 147 0.066
spinal cord motor neuron migration GO:0097476 4 0.066
somatic stem cell maintenance GO:0035019 47 0.066
Mouse
carbohydrate metabolic process GO:0005975 230 0.065
purkinje myocyte differentiation GO:0003168 1 0.065
positive regulation of neuron projection development GO:0010976 79 0.064
spinal cord dorsal ventral patterning GO:0021513 23 0.064
glandular epithelial cell differentiation GO:0002067 38 0.064
Mouse
regulation of anatomical structure size GO:0090066 178 0.064
stem cell fate determination GO:0048867 2 0.064
blood vessel morphogenesis GO:0048514 285 0.063
Mouse
canonical wnt signaling pathway GO:0060070 130 0.063
artery development GO:0060840 53 0.063
Mouse
heart formation GO:0060914 16 0.063
Mouse
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.063
Mouse
chondrocyte differentiation GO:0002062 72 0.062
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.062
cardiac pacemaker cell fate commitment GO:0060927 1 0.062
negative regulation of cellular amine metabolic process GO:0033239 1 0.062
membrane depolarization GO:0051899 64 0.062
response to radiation GO:0009314 165 0.061
nephron tubule development GO:0072080 84 0.061
Mouse
muscle cell development GO:0055001 133 0.061
Mouse
central nervous system neuron development GO:0021954 67 0.061
rostrocaudal neural tube patterning GO:0021903 12 0.061
forebrain regionalization GO:0021871 25 0.061
spinal cord oligodendrocyte cell differentiation GO:0021529 3 0.060
spinal cord motor neuron differentiation GO:0021522 35 0.060
regulation of stem cell proliferation GO:0072091 78 0.060
Fly
metanephric tubule development GO:0072170 18 0.060
Mouse
digestive tract development GO:0048565 190 0.060
Mouse
respiratory system development GO:0060541 190 0.060
Mouse
metanephric tubule morphogenesis GO:0072173 9 0.060
Mouse
positive regulation of stem cell proliferation GO:2000648 59 0.059
Fly
neural tube closure GO:0001843 90 0.059
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.059
compound eye development GO:0048749 1 0.059
Fly
renal tubule development GO:0061326 87 0.059
Mouse
nephron epithelium development GO:0072009 92 0.058
Mouse
cardiac neural crest cell development involved in heart development GO:0061308 7 0.058
Mouse
kidney vasculature development GO:0061440 15 0.058
Mouse
meiotic nuclear division GO:0007126 115 0.058
cation transport GO:0006812 399 0.057
trophectodermal cell differentiation GO:0001829 21 0.057
cranial nerve development GO:0021545 41 0.057
response to light stimulus GO:0009416 135 0.057
branching involved in ureteric bud morphogenesis GO:0001658 56 0.057
establishment of protein localization to organelle GO:0072594 118 0.057
Mouse
cerebellar purkinje cell differentiation GO:0021702 13 0.056
regulation of endodermal cell differentiation GO:1903224 2 0.056
spemann organizer formation GO:0060061 2 0.056
female sex differentiation GO:0046660 84 0.055
cartilage development GO:0051216 140 0.055
Mouse
cellular chemical homeostasis GO:0055082 215 0.055
positive regulation of glial cell differentiation GO:0045687 21 0.055
Mouse
regulation of macrophage colony stimulating factor production GO:1901256 1 0.055
positive regulation of gliogenesis GO:0014015 27 0.055
Mouse
forebrain cell migration GO:0021885 58 0.055
ensheathment of neurons GO:0007272 76 0.054
Mouse
atrioventricular node cell development GO:0060928 2 0.054
regulation of organ formation GO:0003156 34 0.054
Mouse
hypothalamus cell differentiation GO:0021979 8 0.054
tube formation GO:0035148 140 0.054
Mouse
enteroendocrine cell differentiation GO:0035883 16 0.054
Mouse
ventricular septum morphogenesis GO:0060412 27 0.053
Mouse
adult locomotory behavior GO:0008344 91 0.053
pons development GO:0021548 13 0.052
ventral spinal cord interneuron fate determination GO:0060580 1 0.052
negative regulation of oxidative phosphorylation uncoupler activity GO:2000276 2 0.052
renal interstitial fibroblast development GO:0072141 5 0.052
Mouse
regulation of vesicle mediated transport GO:0060627 139 0.052
heart induction GO:0003129 2 0.052
extracellular matrix organization GO:0030198 147 0.051
exocytosis GO:0006887 121 0.051
muscle cell differentiation GO:0042692 261 0.051
Mouse
embryonic skeletal system morphogenesis GO:0048704 91 0.050
cell cell signaling involved in cell fate commitment GO:0045168 35 0.050
Mouse
notch signaling pathway GO:0007219 71 0.050
Mouse
pyramidal neuron migration GO:0021852 1 0.050
molting cycle GO:0042303 90 0.050
organonitrogen compound biosynthetic process GO:1901566 192 0.049
cervix development GO:0060067 2 0.049
oogenesis GO:0048477 56 0.049
mesonephric duct formation GO:0072181 2 0.049
regulation of defense response GO:0031347 233 0.049
negative regulation of osteoblast differentiation GO:0045668 30 0.048
immune effector process GO:0002252 321 0.048
muscle system process GO:0003012 141 0.048
paramesonephric duct development GO:0061205 3 0.047
meiotic cell cycle GO:0051321 122 0.047
regulation of somitogenesis GO:0014807 6 0.047
Mouse
epithalamus development GO:0021538 2 0.047
gonad morphogenesis GO:0035262 1 0.047
semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:0071527 1 0.047
ventricular cardiac myofibril assembly GO:0055005 3 0.047
hemangioblast cell differentiation GO:0060217 1 0.046
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.046
intracellular protein transport GO:0006886 204 0.046
Mouse
atrioventricular node cell fate commitment GO:0060929 1 0.046
dopaminergic neuron differentiation GO:0071542 14 0.045
male gamete generation GO:0048232 285 0.045
cerebellum formation GO:0021588 1 0.045
regulation of cellular ketone metabolic process GO:0010565 66 0.045
regulation of rhodopsin gene expression GO:0007468 3 0.045
monocarboxylic acid biosynthetic process GO:0072330 61 0.045
central nervous system morphogenesis GO:0021551 2 0.045
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.045
glomerulus vasculature development GO:0072012 14 0.044
Mouse
positive regulation of protein modification process GO:0031401 299 0.044
Mouse
epithelial cell maturation involved in prostate gland development GO:0060743 4 0.044
ear morphogenesis GO:0042471 118 0.044
regulation of system process GO:0044057 200 0.044
parasympathetic nervous system development GO:0048486 19 0.043
spinal cord association neuron differentiation GO:0021527 14 0.043
blood circulation GO:0008015 195 0.043
positive regulation of t cell proliferation GO:0042102 52 0.043
Mouse
skeletal muscle organ development GO:0060538 163 0.043
cellular lipid metabolic process GO:0044255 323 0.043
positive regulation of mitotic cell cycle GO:0045931 41 0.042
Mouse
regulation of body fluid levels GO:0050878 162 0.042
cardiac neural crest cell development involved in outflow tract morphogenesis GO:0061309 6 0.042
Mouse
sensory perception of sound GO:0007605 97 0.042
lens development in camera type eye GO:0002088 62 0.042
inner ear morphogenesis GO:0042472 101 0.042
testosterone biosynthetic process GO:0061370 2 0.042
muscle tissue development GO:0060537 308 0.041
feeding behavior GO:0007631 62 0.041
pancreas development GO:0031016 57 0.041
Mouse
positive regulation of growth GO:0045927 104 0.041
regulation of ion transmembrane transport GO:0034765 119 0.041
embryonic epithelial tube formation GO:0001838 130 0.041
Mouse
atrioventricular node cell differentiation GO:0060922 2 0.041
neuron recognition GO:0008038 25 0.041
epithelial cell differentiation involved in kidney development GO:0035850 23 0.041
circulatory system process GO:0003013 197 0.041
female gonad development GO:0008585 71 0.040
atrial cardiac muscle cell development GO:0055014 2 0.040
primary neural tube formation GO:0014020 95 0.040
striated muscle contraction GO:0006941 45 0.040
skin morphogenesis GO:0043589 38 0.039
organic hydroxy compound biosynthetic process GO:1901617 77 0.039
ureteric bud development GO:0001657 94 0.039
Mouse
hair cell differentiation GO:0035315 40 0.039
Mouse
inflammatory response GO:0006954 244 0.039
multicellular organismal homeostasis GO:0048871 164 0.039
development of primary female sexual characteristics GO:0046545 73 0.039
positive regulation of mechanoreceptor differentiation GO:0045633 1 0.038
lateral motor column neuron migration GO:0097477 3 0.038
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.038
adult behavior GO:0030534 135 0.038
fat cell differentiation GO:0045444 160 0.038
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.038
jak stat cascade GO:0007259 42 0.038
Mouse
divalent metal ion transport GO:0070838 172 0.038
regulation of hydrolase activity GO:0051336 246 0.038
renal vesicle induction GO:0072034 3 0.038
determination of heart left right asymmetry GO:0061371 48 0.038
negative regulation of mesodermal cell fate specification GO:0042662 3 0.038
glial cell fate specification GO:0021780 5 0.037
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.037
epidermal cell fate specification GO:0009957 1 0.037
Worm
humoral immune response GO:0006959 57 0.037
mitral valve development GO:0003174 4 0.037
regulation of meiotic cell cycle GO:0051445 34 0.037
glucose metabolic process GO:0006006 92 0.037
negative regulation of mechanoreceptor differentiation GO:0045632 3 0.037
Mouse
mesonephric tubule development GO:0072164 94 0.037
Mouse
regulation of morphogenesis of a branching structure GO:0060688 53 0.037
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development GO:0060528 4 0.036
renal system vasculature development GO:0061437 15 0.036
Mouse
negative regulation of gastrulation GO:2000542 3 0.036
columnar cuboidal epithelial cell development GO:0002066 29 0.036
lens morphogenesis in camera type eye GO:0002089 24 0.036
single organism nuclear import GO:1902593 95 0.036
Mouse
negative regulation of epidermis development GO:0045683 9 0.036
Mouse
midbrain hindbrain boundary maturation during brain development GO:0022004 1 0.036
olfactory bulb interneuron differentiation GO:0021889 12 0.036
transforming growth factor beta2 production GO:0032906 2 0.035
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.035
regulation of mapk cascade GO:0043408 248 0.035
purine containing compound metabolic process GO:0072521 311 0.035
regulation of cellular catabolic process GO:0031329 242 0.035
muscle tissue morphogenesis GO:0060415 53 0.035
lung induction GO:0060492 3 0.035
astrocyte differentiation GO:0048708 43 0.035
Mouse
mesodermal cell differentiation GO:0048333 22 0.035
metal ion homeostasis GO:0055065 189 0.034
lateral sprouting involved in mammary gland duct morphogenesis GO:0060599 2 0.034
negative regulation of intracellular signal transduction GO:1902532 167 0.034
regulation of lymphocyte proliferation GO:0050670 117 0.034
Mouse
interleukin 8 production GO:0032637 4 0.034
cation transmembrane transport GO:0098655 266 0.034
cell fate specification involved in pattern specification GO:0060573 11 0.034
ascending aorta development GO:0035905 3 0.034
Mouse
oocyte development GO:0048599 33 0.034
regulation of myelination GO:0031641 20 0.034
Mouse
forebrain neuron fate commitment GO:0021877 13 0.034
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.034
apoptotic process involved in morphogenesis GO:0060561 25 0.033
cardiac muscle tissue morphogenesis GO:0055008 44 0.033
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.033
cellular modified amino acid metabolic process GO:0006575 63 0.033
negative regulation of cell activation GO:0050866 111 0.033
foramen ovale closure GO:0035922 1 0.033
nuclear import GO:0051170 95 0.033
Mouse
negative regulation of phosphorylation GO:0042326 166 0.033
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.033
tissue remodeling GO:0048771 102 0.032
determination of left right symmetry GO:0007368 80 0.032
limb development GO:0060173 166 0.032
axis elongation involved in somitogenesis GO:0090245 4 0.032
heart trabecula formation GO:0060347 14 0.032
tyrosine phosphorylation of stat protein GO:0007260 23 0.032
Mouse
regulation of notch signaling pathway GO:0008593 35 0.032
Mouse
nuclear transport GO:0051169 139 0.032
Mouse
oligodendrocyte differentiation GO:0048709 53 0.032
Mouse

Hes3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.066
disease of anatomical entity DOID:7 0 0.044
musculoskeletal system disease DOID:17 0 0.044
connective tissue disease DOID:65 0 0.044