Mus musculus

2 known processes

Uba2

ubiquitin-like modifier activating enzyme 2

(Aliases: AA986091,Uble1b,Arx,Ubl1a2,Sae2,UBA1)

Uba2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to dna damage stimulus GO:0006974 207 0.519
gene silencing by mirna GO:0035195 10 0.373
rna localization GO:0006403 23 0.352
dna templated transcription termination GO:0006353 4 0.352
gene silencing by rna GO:0031047 19 0.257
mitotic cell cycle process GO:1903047 159 0.247
gene silencing GO:0016458 38 0.243
organelle fission GO:0048285 170 0.192
regulation of rna splicing GO:0043484 37 0.175
posttranscriptional gene silencing GO:0016441 10 0.163
mitotic cell cycle GO:0000278 195 0.150
posttranscriptional regulation of gene expression GO:0010608 155 0.143
mrna transport GO:0051028 13 0.141
chemotaxis GO:0006935 247 0.123
dna metabolic process GO:0006259 303 0.122
neuron projection guidance GO:0097485 141 0.121
nucleic acid transport GO:0050657 18 0.117
secretory granule organization GO:0033363 20 0.112
peptidyl amino acid modification GO:0018193 336 0.112
endocytosis GO:0006897 168 0.110
chromatin organization GO:0006325 206 0.110
negative regulation of cellular protein metabolic process GO:0032269 247 0.102
nucleobase containing compound transport GO:0015931 27 0.087
chromatin modification GO:0016568 187 0.087
mrna processing GO:0006397 63 0.085
histone acetylation GO:0016573 41 0.083
dna conformation change GO:0071103 37 0.083
cell cycle checkpoint GO:0000075 47 0.082
nuclear transport GO:0051169 139 0.079
spermatogenesis GO:0007283 284 0.077
positive regulation of dna templated transcription elongation GO:0032786 2 0.076
rna interference GO:0016246 2 0.076
protein complex disassembly GO:0043241 40 0.074
axon guidance GO:0007411 141 0.067
nuclear division GO:0000280 158 0.066
spliceosomal complex assembly GO:0000245 6 0.065
protein methylation GO:0006479 81 0.062
regulation of cell cycle GO:0051726 281 0.061
mrna export from nucleus GO:0006406 11 0.059
mrna metabolic process GO:0016071 84 0.057
mrna splicing via spliceosome GO:0000398 43 0.056
male gamete generation GO:0048232 285 0.053
posttranscriptional gene silencing by rna GO:0035194 10 0.051
meiotic cell cycle GO:0051321 122 0.051
protein dna complex subunit organization GO:0071824 28 0.051
lamellipodium organization GO:0097581 29 0.050
nucleocytoplasmic transport GO:0006913 139 0.049
rna transport GO:0050658 18 0.047
positive regulation of gene silencing by mirna GO:2000637 1 0.043
ras protein signal transduction GO:0007265 77 0.043
spermatid differentiation GO:0048515 115 0.041
rna processing GO:0006396 105 0.041
axonogenesis GO:0007409 274 0.039
microtubule based process GO:0007017 236 0.038
dna replication GO:0006260 52 0.038
stem cell development GO:0048864 219 0.038
dna repair GO:0006281 107 0.037
camera type eye development GO:0043010 266 0.037
receptor mediated endocytosis GO:0006898 51 0.037
mrna catabolic process GO:0006402 22 0.036
cellular amino acid metabolic process GO:0006520 103 0.036
protein modification by small protein conjugation or removal GO:0070647 207 0.035
Human Yeast Fly
protein acylation GO:0043543 64 0.035
dna packaging GO:0006323 30 0.033
cytoplasmic transport GO:0016482 234 0.033
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.033
nitrogen compound transport GO:0071705 271 0.032
epithelial to mesenchymal transition GO:0001837 47 0.032
internal peptidyl lysine acetylation GO:0018393 42 0.032
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.031
base excision repair GO:0006284 9 0.031
intracellular mrna localization GO:0008298 4 0.031
positive regulation of rna splicing GO:0033120 12 0.030
negative regulation of pathway restricted smad protein phosphorylation GO:0060394 1 0.029
hematopoietic progenitor cell differentiation GO:0002244 143 0.029
rna splicing GO:0008380 54 0.028
peptidyl lysine modification GO:0018205 77 0.028
gonad development GO:0008406 141 0.028
peptidyl lysine acetylation GO:0018394 45 0.027
fertilization GO:0009566 127 0.027
regulation of cell cycle process GO:0010564 160 0.026
establishment of rna localization GO:0051236 18 0.026
blood circulation GO:0008015 195 0.026
development of primary sexual characteristics GO:0045137 143 0.025
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.025
negative regulation of protein metabolic process GO:0051248 282 0.025
phagocytosis GO:0006909 66 0.024
heart process GO:0003015 94 0.023
histone modification GO:0016570 159 0.023
positive regulation of cell cycle phase transition GO:1901989 17 0.023
amine metabolic process GO:0009308 45 0.023
small gtpase mediated signal transduction GO:0007264 97 0.022
body morphogenesis GO:0010171 45 0.022
cell fate commitment GO:0045165 210 0.022
single organism nuclear import GO:1902593 95 0.022
mesenchymal cell development GO:0014031 93 0.022
regulation of epithelial to mesenchymal transition GO:0010717 22 0.021
cation transmembrane transport GO:0098655 266 0.021
translation GO:0006412 93 0.021
macromolecule methylation GO:0043414 120 0.021
regulation of intracellular protein transport GO:0033157 82 0.020
ribose phosphate metabolic process GO:0019693 291 0.020
protein alkylation GO:0008213 81 0.020
regulation of hormone secretion GO:0046883 88 0.020
rna dependent dna replication GO:0006278 3 0.020
nuclear import GO:0051170 95 0.019
cognition GO:0050890 149 0.019
mesenchyme development GO:0060485 152 0.019
dephosphorylation GO:0016311 129 0.019
rna splicing via transesterification reactions GO:0000375 43 0.019
mitotic nuclear division GO:0007067 48 0.019
nuclear export GO:0051168 34 0.019
regulation of cellular amino acid metabolic process GO:0006521 5 0.019
covalent chromatin modification GO:0016569 163 0.018
negative regulation of cell cycle process GO:0010948 69 0.018
cellular response to inorganic substance GO:0071241 37 0.018
regulation of organelle organization GO:0033043 289 0.017
positive regulation of intracellular transport GO:0032388 70 0.017
hypophysis morphogenesis GO:0048850 3 0.017
internal protein amino acid acetylation GO:0006475 42 0.017
divalent metal ion transport GO:0070838 172 0.017
nucleus organization GO:0006997 45 0.017
apoptotic signaling pathway GO:0097190 306 0.017
methylation GO:0032259 134 0.017
learning or memory GO:0007611 148 0.017
chromatin remodeling GO:0006338 32 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
Human Yeast Fly
cytoplasmic microtubule organization GO:0031122 14 0.016
spermatid development GO:0007286 108 0.016
carbohydrate metabolic process GO:0005975 230 0.016
regulation of ion transmembrane transport GO:0034765 119 0.016
alternative mrna splicing via spliceosome GO:0000380 12 0.016
meiotic chromosome segregation GO:0045132 19 0.016
lipid biosynthetic process GO:0008610 179 0.016
regulation of protein stability GO:0031647 52 0.016
spindle organization GO:0007051 28 0.015
epithelial cell proliferation GO:0050673 174 0.015
protein import into nucleus GO:0006606 95 0.015
positive regulation of receptor biosynthetic process GO:0010870 1 0.015
dna modification GO:0006304 50 0.015
regulation of receptor biosynthetic process GO:0010869 2 0.015
engulfment of apoptotic cell GO:0043652 3 0.015
negative regulation of cell proliferation GO:0008285 296 0.015
positive regulation of mrna splicing via spliceosome GO:0048026 11 0.015
regulation of double strand break repair via nonhomologous end joining GO:2001032 2 0.015
single fertilization GO:0007338 82 0.015
protein localization to nucleus GO:0034504 121 0.015
regulation of epithelial cell proliferation GO:0050678 141 0.015
maintenance of location GO:0051235 89 0.015
response to inorganic substance GO:0010035 96 0.015
regulation of mrna splicing via spliceosome GO:0048024 32 0.014
regulation of mitotic cell cycle GO:0007346 126 0.014
rna catabolic process GO:0006401 29 0.014
maternal determination of anterior posterior axis embryo GO:0008358 2 0.014
digestive system development GO:0055123 200 0.014
sperm individualization GO:0007291 1 0.014
plasma lipoprotein particle clearance GO:0034381 13 0.014
skin development GO:0043588 220 0.014
wnt signaling pathway GO:0016055 188 0.014
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.014
respiratory system development GO:0060541 190 0.014
germ cell development GO:0007281 185 0.013
transcription elongation from rna polymerase ii promoter GO:0006368 9 0.013
organophosphate biosynthetic process GO:0090407 122 0.013
microtubule cytoskeleton organization GO:0000226 157 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.013
learning GO:0007612 98 0.013
forebrain development GO:0030900 302 0.013
cellular ketone metabolic process GO:0042180 84 0.013
actin cytoskeleton organization GO:0030036 220 0.013
genitalia development GO:0048806 37 0.013
response to growth factor GO:0070848 198 0.013
response to peptide GO:1901652 136 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
maintenance of protein localization in organelle GO:0072595 2 0.013
ion transmembrane transport GO:0034220 361 0.013
regulation of stem cell differentiation GO:2000736 50 0.013
nucleotide biosynthetic process GO:0009165 78 0.013
regulation of cellular ketone metabolic process GO:0010565 66 0.012
membrane organization GO:0061024 245 0.012
negative regulation of cell cycle GO:0045786 123 0.012
carbohydrate derivative biosynthetic process GO:1901137 183 0.012
nucleotide metabolic process GO:0009117 332 0.012
maintenance of protein location in nucleus GO:0051457 2 0.012
metaphase plate congression GO:0051310 2 0.012
receptor biosynthetic process GO:0032800 3 0.012
oocyte anterior posterior axis specification GO:0007314 2 0.012
regulation of cell cycle phase transition GO:1901987 77 0.012
ncrna 3 end processing GO:0043628 2 0.012
regulation of mitotic cell cycle phase transition GO:1901990 73 0.012
regulation of hormone levels GO:0010817 211 0.012
positive regulation of cellular amine metabolic process GO:0033240 5 0.012
macromolecular complex disassembly GO:0032984 43 0.012
regulation of nucleocytoplasmic transport GO:0046822 73 0.011
nucleotide catabolic process GO:0009166 217 0.011
regulation of mapk cascade GO:0043408 248 0.011
regulation of cellular response to stress GO:0080135 159 0.011
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.011
positive regulation of programmed cell death GO:0043068 218 0.011
transmission of nerve impulse GO:0019226 76 0.011
negative regulation of protein modification process GO:0031400 163 0.011
negative regulation of cell cycle phase transition GO:1901988 48 0.011
regulation of protein complex disassembly GO:0043244 28 0.011
cardiac muscle contraction GO:0060048 32 0.011
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.011
coenzyme metabolic process GO:0006732 52 0.011
protein targeting GO:0006605 143 0.011
mitotic cytokinesis GO:0000281 4 0.011
cellular macromolecule catabolic process GO:0044265 206 0.010
regulation of dna templated transcription elongation GO:0032784 10 0.010
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.010
protein localization to organelle GO:0033365 185 0.010
muscle system process GO:0003012 141 0.010
circulatory system process GO:0003013 197 0.010
negative regulation of rna splicing GO:0033119 12 0.010
nucleoside phosphate biosynthetic process GO:1901293 79 0.010

Uba2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cornelia de lange syndrome DOID:11725 0 0.020