IMP

Process View

Mus musculus

20 genes annotated in mouse

secretory granule organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "secretory granule organization"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "secretory granule organization" (in gray)

Name	Description	Probability	Func Analog Organism
Hps1	Hermansky-Pudlak syndrome 1 homolog (human)	0.971
Ndel1	nuclear distribution gene E-like homolog 1 (A. nidulans)	0.760
Mitf	microphthalmia-associated transcription factor	0.725
Gtf2a1	general transcription factor II A, 1	0.591
Maff	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)	0.580
Ap3b1	adaptor-related protein complex 3, beta 1 subunit	0.565
Rab27a	RAB27A, member RAS oncogene family	0.537
Hps6	Hermansky-Pudlak syndrome 6	0.403
Hps5	Hermansky-Pudlak syndrome 5 homolog (human)	0.400
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.390
Cno	cappuccino	0.315
Taf3	TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor	0.313
Nde1	nuclear distribution gene E homolog 1 (A nidulans)	0.213
Sh3gl3	SH3-domain GRB2-like 3	0.185
Apoe	apolipoprotein E	0.183
Slc24a5	solute carrier family 24, member 5	0.179
Amelx	amelogenin X chromosome	0.177
Tyr	tyrosinase	0.164
Fads2	fatty acid desaturase 2	0.152
Abcg1	ATP-binding cassette, sub-family G (WHITE), member 1	0.134
Npc1	Niemann Pick type C1	0.133
Myo5a	myosin VA	0.131
a	nonagouti	0.124
Tyrp1	tyrosinase-related protein 1	0.122
Uba2	ubiquitin-like modifier activating enzyme 2	0.112
Ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.112
Pou5f1	POU domain, class 5, transcription factor 1	0.111
Atf1	activating transcription factor 1	0.089	Mouse
Pmel	premelanosome protein	0.085
Mlph	melanophilin	0.082
Lbr	lamin B receptor	0.079
Hnrpll	heterogeneous nuclear ribonucleoprotein L-like	0.074
Dek	DEK oncogene (DNA binding)	0.067
Hps4	Hermansky-Pudlak syndrome 4 homolog (human)	0.063
Mta2	metastasis-associated gene family, member 2	0.063
Pldn	pallidin	0.056
Btbd10	BTB (POZ) domain containing 10	0.051
Capza1	capping protein (actin filament) muscle Z-line, alpha 1	0.050
Dtnb	dystrobrevin, beta	0.047
Smndc1	survival motor neuron domain containing 1	0.047
Agfg1	ArfGAP with FG repeats 1	0.045
Rab38	RAB38, member of RAS oncogene family	0.044	Rat
Gucy1a3	guanylate cyclase 1, soluble, alpha 3	0.043
Oca2	oculocutaneous albinism II	0.042
Tinagl1	tubulointerstitial nephritis antigen-like 1	0.041
Zfp143	zinc finger protein 143	0.039
Hps3	Hermansky-Pudlak syndrome 3 homolog (human)	0.039
Sec23ip	Sec23 interacting protein	0.039
Ptpn2	protein tyrosine phosphatase, non-receptor type 2	0.039
Nfya	nuclear transcription factor-Y alpha	0.038
Pknox1	Pbx/knotted 1 homeobox	0.037
Fam49b	family with sequence similarity 49, member B	0.036
Fam20a	family with sequence similarity 20, member A	0.036
Lrp5	low density lipoprotein receptor-related protein 5	0.035
Eps15	epidermal growth factor receptor pathway substrate 15	0.035
Itga5	integrin alpha 5 (fibronectin receptor alpha)	0.034
Zfpm1	zinc finger protein, multitype 1	0.034
Gtf2b	general transcription factor IIB	0.033
Smarca5	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	0.032
Tnks1bp1	tankyrase 1 binding protein 1	0.031
Lsm14a	LSM14 homolog A (SCD6, S. cerevisiae)	0.031
Gdap2	ganglioside-induced differentiation-associated-protein 2	0.030
Foxp4	forkhead box P4	0.029
Epha2	Eph receptor A2	0.029
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.028
Cyr61	cysteine rich protein 61	0.027
Cldn3	claudin 3	0.027
Ifrd1	interferon-related developmental regulator 1	0.026
Procr	protein C receptor, endothelial	0.025
Ptgs2	prostaglandin-endoperoxide synthase 2	0.025
Lrp1	low density lipoprotein receptor-related protein 1	0.025
Api5	apoptosis inhibitor 5	0.024
Nras	neuroblastoma ras oncogene	0.024
Clip1	CAP-GLY domain containing linker protein 1	0.024
Nck1	non-catalytic region of tyrosine kinase adaptor protein 1	0.024
Max	Max protein	0.023
Tbpl1	TATA box binding protein-like 1	0.023
Tmprss11e	transmembrane protease, serine 11e	0.023
Sntb2	syntrophin, basic 2	0.023
Zfp131	zinc finger protein 131	0.023
Xiap	X-linked inhibitor of apoptosis	0.023
Rnf2	ring finger protein 2	0.023
Muc1	mucin 1, transmembrane	0.023
Crebl2	cAMP responsive element binding protein-like 2	0.022
Taf5	TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor	0.022
Kitl	kit ligand	0.022
Lyst	lysosomal trafficking regulator	0.022
Dtna	dystrobrevin alpha	0.022
Epha1	Eph receptor A1	0.022
Rad17	RAD17 homolog (S. pombe)	0.021
S1pr1	sphingosine-1-phosphate receptor 1	0.021
Atf3	activating transcription factor 3	0.021
Elf3	E74-like factor 3	0.020
Ap3d1	adaptor-related protein complex 3, delta 1 subunit	0.020
Hbegf	heparin-binding EGF-like growth factor	0.019
Samd4b	sterile alpha motif domain containing 4B	0.019
Tnfrsf12a	tumor necrosis factor receptor superfamily, member 12a	0.019
Il2rg	interleukin 2 receptor, gamma chain	0.019
Errfi1	ERBB receptor feedback inhibitor 1	0.019
Cebpg	CCAAT/enhancer binding protein (C/EBP), gamma	0.018
Col4a1	collagen, type IV, alpha 1	0.018
Abcg5	ATP-binding cassette, sub-family G (WHITE), member 5	0.018
Stk17b	serine/threonine kinase 17b (apoptosis-inducing)	0.018
Nup153	nucleoporin 153	0.018
Slc4a1ap	solute carrier family 4 (anion exchanger), member 1, adaptor protein	0.018
Muted	muted	0.018
Chd1	chromodomain helicase DNA binding protein 1	0.018
Tnfaip6	tumor necrosis factor alpha induced protein 6	0.018
Fkbp5	FK506 binding protein 5	0.017
Cpne1	copine I	0.017
Acot9	acyl-CoA thioesterase 9	0.017
Tgfbr1	transforming growth factor, beta receptor I	0.017
Adm	adrenomedullin	0.017
Ythdf1	YTH domain family 1	0.017
Rnf19a	ring finger protein 19A	0.017
Tgm2	transglutaminase 2, C polypeptide	0.017
Wdtc1	WD and tetratricopeptide repeats 1	0.017
Llgl2	lethal giant larvae homolog 2 (Drosophila)	0.017
Cldn7	claudin 7	0.016
Zzz3	zinc finger, ZZ domain containing 3	0.016
Osmr	oncostatin M receptor	0.016
Gem	GTP binding protein (gene overexpressed in skeletal muscle)	0.016
Cmya5	cardiomyopathy associated 5	0.016
Gpbp1	GC-rich promoter binding protein 1	0.016
Dr1	down-regulator of transcription 1	0.016
Pdzk1ip1	PDZK1 interacting protein 1	0.016
Bmp2k	BMP2 inducible kinase	0.016
Ate1	arginyltransferase 1	0.015
Actr3	ARP3 actin-related protein 3 homolog (yeast)	0.015
Ddhd1	DDHD domain containing 1	0.015
Spata24	spermatogenesis associated 24	0.015
3110043O21Rik	RIKEN cDNA 3110043O21 gene	0.015
Slc26a1	solute carrier family 26 (sulfate transporter), member 1	0.015
Epcam	epithelial cell adhesion molecule	0.015
Anapc4	anaphase promoting complex subunit 4	0.015
Ankrd27	ankyrin repeat domain 27 (VPS9 domain)	0.015
Zfp36	zinc finger protein 36	0.015
Cd53	CD53 antigen	0.015
Chic2	cysteine-rich hydrophobic domain 2	0.015
Wwc2	WW, C2 and coiled-coil domain containing 2	0.015
Vapa	vesicle-associated membrane protein, associated protein A	0.015
Pcdh1	protocadherin 1	0.014
Plaur	plasminogen activator, urokinase receptor	0.014
Mark4	MAP/microtubule affinity-regulating kinase 4	0.014
Cxcl1	chemokine (C-X-C motif) ligand 1	0.014
Rbbp7	retinoblastoma binding protein 7	0.014
Clcn1	chloride channel 1	0.014
Mllt4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.014
1700020D05Rik	RIKEN cDNA 1700020D05 gene	0.014
Ptgs1	prostaglandin-endoperoxide synthase 1	0.014
Tmprss2	transmembrane protease, serine 2	0.014
Git1	G protein-coupled receptor kinase-interactor 1	0.014
Spry4	sprouty homolog 4 (Drosophila)	0.014
Parg	poly (ADP-ribose) glycohydrolase	0.014
Usp1	ubiquitin specific peptidase 1	0.014
St14	suppression of tumorigenicity 14 (colon carcinoma)	0.014
Ier3	immediate early response 3	0.014
Mtdh	metadherin	0.014
Tfdp1	transcription factor Dp 1	0.014
Atp6v1c2	ATPase, H+ transporting, lysosomal V1 subunit C2	0.014
Mt1	metallothionein 1	0.013
Tial1	Tia1 cytotoxic granule-associated RNA binding protein-like 1	0.013
Bag3	BCL2-associated athanogene 3	0.013
Ccz1	CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)	0.013
Nccrp1	non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)	0.013
Cdyl	chromodomain protein, Y chromosome-like	0.013
Bhlhe40	basic helix-loop-helix family, member e40	0.013
Kit	kit oncogene	0.013
Gcnt2	glucosaminyl (N-acetyl) transferase 2, I-branching enzyme	0.013
Fndc3b	fibronectin type III domain containing 3B	0.013
Rbm15	RNA binding motif protein 15	0.013
Srcin1	SRC kinase signaling inhibitor 1	0.013
Fzd4	frizzled homolog 4 (Drosophila)	0.013
Smagp	small cell adhesion glycoprotein	0.012
Atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.012
Kcnj1	potassium inwardly-rectifying channel, subfamily J, member 1	0.012
Ncoa2	nuclear receptor coactivator 2	0.012
Gml	GPI anchored molecule like protein	0.012
Cyb5r4	cytochrome b5 reductase 4	0.012
Rhou	ras homolog gene family, member U	0.012
Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.012
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.012
Nup54	nucleoporin 54	0.012
Fhl5	four and a half LIM domains 5	0.012
Skil	SKI-like	0.012
Aqp3	aquaporin 3	0.012
4931417E11Rik	RIKEN cDNA 4931417E11 gene	0.012
Tiparp	TCDD-inducible poly(ADP-ribose) polymerase	0.012
Gabrg3	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3	0.012
Hipk1	homeodomain interacting protein kinase 1	0.012
Timp3	tissue inhibitor of metalloproteinase 3	0.012
Ildr1	immunoglobulin-like domain containing receptor 1	0.011
Apoa1	apolipoprotein A-I	0.011
Krt7	keratin 7	0.011
Iars	isoleucine-tRNA synthetase	0.011
Pde4b	phosphodiesterase 4B, cAMP specific	0.011
Med7	mediator complex subunit 7	0.011
2810422J05Rik	RIKEN cDNA 2810422J05 gene	0.011
Rrs1	RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)	0.011
Arhgap8	Rho GTPase activating protein 8	0.011
Hpn	hepsin	0.011
Pikfyve	phosphoinositide kinase, FYVE finger containing	0.011
Fbxo30	F-box protein 30	0.011
Taf1b	TATA box binding protein (Tbp)-associated factor, RNA polymerase I, B	0.011
Pde8a	phosphodiesterase 8A	0.011
Scnn1g	sodium channel, nonvoltage-gated 1 gamma	0.011
Sav1	salvador homolog 1 (Drosophila)	0.011
Pak2	p21 protein (Cdc42/Rac)-activated kinase 2	0.011
Foxn2	forkhead box N2	0.011
Hspa2	heat shock protein 2	0.011
Wbp4	WW domain binding protein 4	0.011
4933424B01Rik	RIKEN cDNA 4933424B01 gene	0.011
Cish	cytokine inducible SH2-containing protein	0.011
Rhot1	ras homolog gene family, member T1	0.011
Grb2	growth factor receptor bound protein 2	0.011
Etf1	eukaryotic translation termination factor 1	0.011
Crlf3	cytokine receptor-like factor 3	0.011
Snip1	Smad nuclear interacting protein 1	0.011
Rhod	ras homolog gene family, member D	0.011
Hmox1	heme oxygenase (decycling) 1	0.011
Furin	furin (paired basic amino acid cleaving enzyme)	0.011
Taf7	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor	0.011
Sap30	sin3 associated polypeptide	0.011
Homer1	homer homolog 1 (Drosophila)	0.011
Slc16a8	solute carrier family 16 (monocarboxylic acid transporters), member 8	0.011
Timp1	tissue inhibitor of metalloproteinase 1	0.011
Mecp2	methyl CpG binding protein 2	0.011
Fst	follistatin	0.011
Mbd1	methyl-CpG binding domain protein 1	0.011
Zfand2a	zinc finger, AN1-type domain 2A	0.011
Rfwd2	ring finger and WD repeat domain 2	0.011
Wtap	Wilms' tumour 1-associating protein	0.011
Ythdf2	YTH domain family 2	0.011
Epas1	endothelial PAS domain protein 1	0.011
Hcfc2	host cell factor C2	0.010
2310016C08Rik	RIKEN cDNA 2310016C08 gene	0.010
Mc1r	melanocortin 1 receptor	0.010
Ero1l	ERO1-like (S. cerevisiae)	0.010
Jdp2	Jun dimerization protein 2	0.010
Dcun1d5	DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae)	0.010
Fem1b	feminization 1 homolog b (C. elegans)	0.010
Stam2	signal transducing adaptor molecule (SH3 domain and ITAM motif) 2	0.010
Ampd3	adenosine monophosphate deaminase 3	0.010
Pign	phosphatidylinositol glycan anchor biosynthesis, class N	0.010
D1Pas1	DNA segment, Chr 1, Pasteur Institute 1	0.010
Lamtor3	late endosomal/lysosomal adaptor, MAPK and MTOR activator 3	0.010
Ugcg	UDP-glucose ceramide glucosyltransferase	0.010
Ppp4r1	protein phosphatase 4, regulatory subunit 1	0.010
Hip1r	huntingtin interacting protein 1 related	0.010
Obfc2a	oligonucleotide/oligosaccharide-binding fold containing 2A	0.010
Cdc42se2	CDC42 small effector 2	0.010
Gadd45b	growth arrest and DNA-damage-inducible 45 beta	0.010
Ifngr1	interferon gamma receptor 1	0.010
Kctd9	potassium channel tetramerisation domain containing 9	0.010
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.010
Msl2	male-specific lethal 2 homolog (Drosophila)	0.010
Folr1	folate receptor 1 (adult)	0.010
Emx1	empty spiracles homolog 1 (Drosophila)	0.010