Mus musculus

116 known processes

Cftr

cystic fibrosis transmembrane conductance regulator homolog

(Aliases: Abcc7,AW495489)

Cftr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ion transmembrane transport GO:0034220 361 0.952
organic anion transport GO:0015711 137 0.922
sodium ion transmembrane transport GO:0035725 49 0.915
spermatid development GO:0007286 108 0.901
anion transmembrane transport GO:0098656 71 0.861
male gamete generation GO:0048232 285 0.840
anion transport GO:0006820 177 0.808
regulation of ph GO:0006885 26 0.799
epithelial cell development GO:0002064 159 0.749
transepithelial chloride transport GO:0030321 4 0.720
Rat
chloride transport GO:0006821 32 0.704
inorganic cation transmembrane transport GO:0098662 207 0.701
spermatid differentiation GO:0048515 115 0.698
monovalent inorganic cation homeostasis GO:0055067 33 0.698
acid secretion GO:0046717 33 0.690
carboxylic acid transport GO:0046942 100 0.672
cation transmembrane transport GO:0098655 266 0.668
organic acid transport GO:0015849 101 0.639
monocarboxylic acid transport GO:0015718 44 0.614
cation homeostasis GO:0055080 212 0.602
inorganic anion transport GO:0015698 43 0.590
inorganic ion transmembrane transport GO:0098660 234 0.583
sulfur compound transport GO:0072348 9 0.575
chloride transmembrane transport GO:1902476 24 0.565
spermatogenesis GO:0007283 284 0.562
regulation of cellular ph GO:0030641 12 0.562
mechanoreceptor differentiation GO:0042490 67 0.548
cellular ion homeostasis GO:0006873 165 0.531
urogenital system development GO:0001655 261 0.506
cellular chemical homeostasis GO:0055082 215 0.486
bicarbonate transport GO:0015701 7 0.479
nitrogen compound transport GO:0071705 271 0.460
regulation of cellular response to stress GO:0080135 159 0.442
intestinal absorption GO:0050892 13 0.432
fluid transport GO:0042044 14 0.417
Rat
transmembrane transport GO:0055085 412 0.416
inner ear receptor cell development GO:0060119 39 0.412
cation transport GO:0006812 399 0.392
positive regulation of apoptotic signaling pathway GO:2001235 95 0.391
protein maturation GO:0051604 176 0.375
multicellular organism growth GO:0035264 161 0.372
positive regulation of apoptotic process GO:0043065 217 0.369
intrinsic apoptotic signaling pathway GO:0097193 132 0.364
cellular homeostasis GO:0019725 240 0.362
peptide transport GO:0015833 133 0.362
amide transport GO:0042886 138 0.342
epithelial cell proliferation GO:0050673 174 0.330
kidney epithelium development GO:0072073 121 0.323
nephron development GO:0072006 109 0.317
sensory organ morphogenesis GO:0090596 242 0.316
positive regulation of programmed cell death GO:0043068 218 0.311
protein processing GO:0016485 163 0.309
gland development GO:0048732 330 0.303
camera type eye development GO:0043010 266 0.297
cell maturation GO:0048469 127 0.295
macroautophagy GO:0016236 21 0.282
digestive tract development GO:0048565 190 0.282
renal system development GO:0072001 225 0.280
forebrain development GO:0030900 302 0.276
ear development GO:0043583 200 0.271
oligopeptide transmembrane transport GO:0035672 4 0.267
autophagy GO:0006914 45 0.266
epithelial tube morphogenesis GO:0060562 303 0.261
cellular amino acid metabolic process GO:0006520 103 0.257
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.256
regulation of autophagy GO:0010506 30 0.250
regulation of protein localization GO:0032880 231 0.250
dna metabolic process GO:0006259 303 0.245
cellular amine metabolic process GO:0044106 44 0.238
photoreceptor cell differentiation GO:0046530 52 0.237
regulation of transmembrane transport GO:0034762 128 0.237
Human
kidney development GO:0001822 213 0.235
nephron tubule development GO:0072080 84 0.234
regulation of lipid metabolic process GO:0019216 118 0.233
regulation of system process GO:0044057 200 0.232
Rat
cellular response to carbohydrate stimulus GO:0071322 50 0.225
sodium ion transport GO:0006814 73 0.224
dipeptide transport GO:0042938 2 0.221
positive regulation of cell death GO:0010942 224 0.217
regulation of secretion GO:0051046 274 0.217
regionalization GO:0003002 337 0.214
toll like receptor signaling pathway GO:0002224 38 0.212
cellular ketone metabolic process GO:0042180 84 0.209
negative regulation of phosphorylation GO:0042326 166 0.209
regulation of hydrolase activity GO:0051336 246 0.207
regulation of organ morphogenesis GO:2000027 144 0.205
germ cell development GO:0007281 185 0.203
negative regulation of cellular protein metabolic process GO:0032269 247 0.201
regulation of body fluid levels GO:0050878 162 0.191
female sex differentiation GO:0046660 84 0.190
nephron epithelium development GO:0072009 92 0.188
cellular response to organonitrogen compound GO:0071417 145 0.184
negative regulation of cell proliferation GO:0008285 296 0.183
lipid localization GO:0010876 126 0.182
lipid transport GO:0006869 98 0.180
glomerulus development GO:0032835 40 0.178
steroid metabolic process GO:0008202 119 0.175
positive regulation of autophagy GO:0010508 9 0.175
regulation of membrane potential GO:0042391 192 0.174
epidermis development GO:0008544 187 0.173
regulation of cell migration GO:0030334 219 0.172
Zebrafish
amine metabolic process GO:0009308 45 0.171
regulation of cellular amine metabolic process GO:0033238 20 0.170
homeostasis of number of cells GO:0048872 210 0.170
ear morphogenesis GO:0042471 118 0.168
negative regulation of nervous system development GO:0051961 156 0.167
inner ear receptor cell differentiation GO:0060113 61 0.166
positive regulation of endopeptidase activity GO:0010950 43 0.165
organelle assembly GO:0070925 177 0.163
cytokine production GO:0001816 319 0.162
development of primary female sexual characteristics GO:0046545 73 0.160
organic hydroxy compound transport GO:0015850 93 0.159
skin development GO:0043588 220 0.158
second messenger mediated signaling GO:0019932 73 0.156
morphogenesis of a branching epithelium GO:0061138 193 0.153
regulation of cell motility GO:2000145 236 0.153
Zebrafish
regulation of kinase activity GO:0043549 249 0.152
digestive system development GO:0055123 200 0.151
ph elevation GO:0045852 3 0.151
carbohydrate metabolic process GO:0005975 230 0.148
eye photoreceptor cell differentiation GO:0001754 41 0.147
positive regulation of neuron differentiation GO:0045666 141 0.147
response to organonitrogen compound GO:0010243 246 0.145
regulation of response to wounding GO:1903034 189 0.144
positive regulation of cellular catabolic process GO:0031331 148 0.144
monosaccharide metabolic process GO:0005996 106 0.143
innate immune response GO:0045087 157 0.142
carbon catabolite regulation of transcription GO:0045990 4 0.140
regulation of hormone levels GO:0010817 211 0.140
regulation of anion transport GO:0044070 27 0.138
Human
response to organophosphorus GO:0046683 22 0.135
transmission of nerve impulse GO:0019226 76 0.133
renal tubule development GO:0061326 87 0.133
respiratory system development GO:0060541 190 0.132
Rat
peptidyl amino acid modification GO:0018193 336 0.131
ovulation cycle GO:0042698 59 0.131
immune response regulating signaling pathway GO:0002764 125 0.131
translation GO:0006412 93 0.131
neuron projection guidance GO:0097485 141 0.130
carbohydrate transport GO:0008643 62 0.129
activation of immune response GO:0002253 138 0.128
glucose metabolic process GO:0006006 92 0.127
regulation of epithelial cell proliferation GO:0050678 141 0.126
female gonad development GO:0008585 71 0.125
developmental programmed cell death GO:0010623 41 0.125
lung development GO:0030324 164 0.119
Rat
inorganic anion transmembrane transport GO:0098661 29 0.117
coagulation GO:0050817 78 0.116
hormone metabolic process GO:0042445 86 0.115
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.115
sulfate transmembrane transport GO:1902358 3 0.112
cellular lipid metabolic process GO:0044255 323 0.110
cellular response to hexose stimulus GO:0071331 47 0.109
ureteric bud development GO:0001657 94 0.109
pancreas development GO:0031016 57 0.109
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.107
regulation of neuron differentiation GO:0045664 281 0.106
regulation of cellular ketone metabolic process GO:0010565 66 0.105
metanephric nephron development GO:0072210 34 0.105
positive regulation of glial cell proliferation GO:0060252 4 0.103
negative regulation of protein metabolic process GO:0051248 282 0.103
regulation of fatty acid metabolic process GO:0019217 28 0.103
response to organic cyclic compound GO:0014070 198 0.103
negative regulation of phosphate metabolic process GO:0045936 184 0.102
synaptic transmission GO:0007268 329 0.100
cell cell adhesion GO:0098609 41 0.100
negative regulation of intracellular signal transduction GO:1902532 167 0.100
regulation of platelet derived growth factor receptor signaling pathway GO:0010640 9 0.099
cell growth GO:0016049 130 0.099
cellular response to monosaccharide stimulus GO:0071326 47 0.099
positive regulation of transcription from rna polymerase ii promoter by glucose GO:0000432 3 0.097
connective tissue development GO:0061448 179 0.096
mapk cascade GO:0000165 281 0.095
carbon catabolite activation of transcription GO:0045991 4 0.095
regulation of dipeptide transmembrane transport GO:2001148 2 0.093
regulation of cellular catabolic process GO:0031329 242 0.093
dicarboxylic acid transport GO:0006835 29 0.092
regulation of cysteine type endopeptidase activity GO:2000116 65 0.092
myeloid cell differentiation GO:0030099 233 0.091
sensory perception GO:0007600 245 0.091
pattern recognition receptor signaling pathway GO:0002221 47 0.091
carbohydrate derivative biosynthetic process GO:1901137 183 0.090
protein autophosphorylation GO:0046777 61 0.090
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 25 0.090
immune effector process GO:0002252 321 0.089
Zebrafish
regulation of translation GO:0006417 71 0.088
innate immune response activating signal transduction GO:0002758 50 0.088
regulation of synaptic transmission gabaergic GO:0032228 17 0.088
cellular carbohydrate metabolic process GO:0044262 119 0.088
multicellular organismal signaling GO:0035637 91 0.088
cellular response to gonadotropin stimulus GO:0071371 4 0.087
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.087
auditory receptor cell development GO:0060117 20 0.087
response to acid chemical GO:0001101 111 0.086
tissue homeostasis GO:0001894 115 0.085
negative regulation of transcription from rna polymerase ii promoter by glucose GO:0000433 1 0.085
hepaticobiliary system development GO:0061008 67 0.084
rhythmic process GO:0048511 174 0.084
intracellular ph elevation GO:0051454 3 0.083
multicellular organismal aging GO:0010259 24 0.082
inner ear receptor stereocilium organization GO:0060122 23 0.082
regulation of oligopeptide transport GO:0090088 2 0.082
response to radiation GO:0009314 165 0.081
leukocyte differentiation GO:0002521 342 0.081
hair cell differentiation GO:0035315 40 0.081
negative regulation of molecular function GO:0044092 258 0.080
posttranscriptional regulation of gene expression GO:0010608 155 0.080
cellular component assembly involved in morphogenesis GO:0010927 139 0.080
regulation of reactive oxygen species metabolic process GO:2000377 40 0.080
nephron morphogenesis GO:0072028 69 0.080
hexose metabolic process GO:0019318 98 0.080
chromatin organization GO:0006325 206 0.080
cellular response to biotic stimulus GO:0071216 92 0.079
regulation of cell adhesion mediated by integrin GO:0033628 13 0.079
male sex differentiation GO:0046661 109 0.078
reactive oxygen species metabolic process GO:0072593 84 0.078
regulation of erk1 and erk2 cascade GO:0070372 71 0.078
digestive tract morphogenesis GO:0048546 147 0.078
regulation of endopeptidase activity GO:0052548 89 0.077
response to osmotic stress GO:0006970 21 0.077
amino acid transport GO:0006865 61 0.076
mesonephric epithelium development GO:0072163 94 0.076
embryonic organ morphogenesis GO:0048562 276 0.076
cell type specific apoptotic process GO:0097285 268 0.075
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development GO:0060528 4 0.075
inner ear morphogenesis GO:0042472 101 0.075
ossification GO:0001503 216 0.075
regulation of homeostatic process GO:0032844 182 0.075
positive regulation of innate immune response GO:0045089 80 0.075
skeletal system development GO:0001501 356 0.074
auditory receptor cell differentiation GO:0042491 37 0.074
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.074
muscle system process GO:0003012 141 0.073
development of primary sexual characteristics GO:0045137 143 0.073
cell adhesion GO:0007155 329 0.073
membrane hyperpolarization GO:0060081 21 0.073
metanephric capsule morphogenesis GO:0072265 1 0.073
anatomical structure homeostasis GO:0060249 145 0.072
kidney morphogenesis GO:0060993 83 0.072
protein kinase c signaling GO:0070528 7 0.072
regulation of glucose metabolic process GO:0010906 60 0.072
stem cell differentiation GO:0048863 268 0.072
blastocyst development GO:0001824 80 0.071
cardiac muscle tissue development GO:0048738 130 0.070
action potential GO:0001508 78 0.069
bile acid and bile salt transport GO:0015721 5 0.068
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.068
respiratory tube development GO:0030323 167 0.068
Rat
epithelial cell maturation involved in prostate gland development GO:0060743 4 0.068
regulation of peptidase activity GO:0052547 96 0.067
extracellular structure organization GO:0043062 148 0.067
purine containing compound metabolic process GO:0072521 311 0.067
positive regulation of cellular amine metabolic process GO:0033240 5 0.067
multicellular organismal homeostasis GO:0048871 164 0.066
cellular response to growth factor stimulus GO:0071363 197 0.066
gastric acid secretion GO:0001696 6 0.066
placenta development GO:0001890 140 0.066
activation of cysteine type endopeptidase activity GO:0097202 27 0.066
response to arsenic containing substance GO:0046685 5 0.065
positive regulation of dipeptide transmembrane transport GO:2001150 2 0.065
regulation of antimicrobial humoral response GO:0002759 3 0.065
ribonucleotide metabolic process GO:0009259 291 0.064
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.064
mesonephric tubule development GO:0072164 94 0.064
regulation of neurotransmitter levels GO:0001505 87 0.064
response to molecule of bacterial origin GO:0002237 143 0.064
camp mediated signaling GO:0019933 15 0.063
granulosa cell differentiation GO:0060014 1 0.063
regulation of toll like receptor signaling pathway GO:0034121 20 0.063
muscle cell differentiation GO:0042692 261 0.063
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.063
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.062
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.062
cell differentiation involved in kidney development GO:0061005 33 0.062
organic hydroxy compound metabolic process GO:1901615 203 0.062
regulation of protein transport GO:0051223 163 0.062
activation of innate immune response GO:0002218 56 0.062
regulation of stem cell differentiation GO:2000736 50 0.061
positive regulation of intracellular estrogen receptor signaling pathway GO:0033148 4 0.061
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.061
negative regulation of cellular component organization GO:0051129 194 0.061
negative regulation of phosphorus metabolic process GO:0010563 184 0.061
ensheathment of neurons GO:0007272 76 0.060
axonogenesis GO:0007409 274 0.060
apoptotic signaling pathway GO:0097190 306 0.060
proton transport GO:0015992 35 0.060
cilium assembly GO:0042384 81 0.059
positive regulation of inositol phosphate biosynthetic process GO:0060732 2 0.059
mesonephros development GO:0001823 97 0.059
regulation of cellular component size GO:0032535 121 0.059
cardiac muscle cell differentiation GO:0055007 69 0.058
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.058
cellular response to lipid GO:0071396 145 0.058
response to monosaccharide GO:0034284 67 0.058
sensory perception of pain GO:0019233 47 0.058
cellular response to peptide GO:1901653 92 0.058
extracellular matrix organization GO:0030198 147 0.058
axial mesoderm development GO:0048318 8 0.058
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.058
regulation of synaptic plasticity GO:0048167 87 0.057
cellular response to fructose stimulus GO:0071332 2 0.057
response to lipopolysaccharide GO:0032496 128 0.057
skeletal system morphogenesis GO:0048705 203 0.057
regulation of defense response GO:0031347 233 0.057
morphogenesis of a branching structure GO:0001763 203 0.057
acetate ester metabolic process GO:1900619 3 0.057
sensory perception of mechanical stimulus GO:0050954 107 0.056
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.056
regulation of establishment of protein localization GO:0070201 181 0.056
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.055
glomerular mesangial cell differentiation GO:0072008 3 0.055
b cell differentiation GO:0030183 78 0.055
sperm capacitation GO:0048240 17 0.055
regulation of proteolysis GO:0030162 164 0.055
regulation of peptide hormone secretion GO:0090276 75 0.055
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.055
positive regulation of hydrolase activity GO:0051345 148 0.055
response to nutrient levels GO:0031667 109 0.054
positive regulation of macroautophagy GO:0016239 3 0.054
detection of glucose GO:0051594 1 0.054
regulation of cilium assembly GO:1902017 7 0.053
striated muscle tissue development GO:0014706 293 0.053
ureteric bud morphogenesis GO:0060675 62 0.053
positive regulation of cell development GO:0010720 237 0.053
regulation of peptide transport GO:0090087 91 0.053
regulation of cell projection organization GO:0031344 206 0.053
mitotic cell cycle GO:0000278 195 0.053
long term synaptic potentiation GO:0060291 25 0.053
wnt signaling pathway involved in kidney development GO:0061289 2 0.053
tissue remodeling GO:0048771 102 0.053
rho protein signal transduction GO:0007266 32 0.053
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 4 0.053
retinal cell programmed cell death GO:0046666 8 0.052
cellular response to molecule of bacterial origin GO:0071219 83 0.052
cellular response to hormone stimulus GO:0032870 150 0.052
Rat
retina vasculature development in camera type eye GO:0061298 17 0.052
digestion GO:0007586 40 0.051
regulation of transferase activity GO:0051338 263 0.051
neuron migration GO:0001764 122 0.051
erk1 and erk2 cascade GO:0070371 77 0.051
regulation of secretion by cell GO:1903530 249 0.051
nucleoside metabolic process GO:0009116 246 0.051
immune response activating signal transduction GO:0002757 116 0.050
response to light stimulus GO:0009416 135 0.050
regulation of mapk cascade GO:0043408 248 0.050
mesenchymal cell development GO:0014031 93 0.049
determination of adult lifespan GO:0008340 11 0.049
morphogenesis of embryonic epithelium GO:0016331 159 0.049
cellular response to lipopolysaccharide GO:0071222 77 0.048
regulation of protein maturation GO:1903317 96 0.048
peptidyl tyrosine modification GO:0018212 145 0.048
glycerolipid metabolic process GO:0046486 122 0.048
regulation of inflammatory response GO:0050727 147 0.047
regulation of carbohydrate metabolic process GO:0006109 75 0.047
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.047
oligopeptide transport GO:0006857 6 0.047
positive regulation of peptidase activity GO:0010952 49 0.047
positive regulation of transcription from rna polymerase iii promoter GO:0045945 1 0.047
regulation of neuron apoptotic process GO:0043523 122 0.047
insulin secretion GO:0030073 89 0.046
wound healing GO:0042060 157 0.046
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.046
lymphocyte differentiation GO:0030098 242 0.045
regulation of anatomical structure size GO:0090066 178 0.045
Rat
nephron epithelium morphogenesis GO:0072088 68 0.045
purine ribonucleotide metabolic process GO:0009150 290 0.045
organophosphate biosynthetic process GO:0090407 122 0.045
response to endoplasmic reticulum stress GO:0034976 53 0.045
negative regulation of hexokinase activity GO:1903300 4 0.045
hormone secretion GO:0046879 128 0.045
cilium morphogenesis GO:0060271 102 0.045
intermediate filament cytoskeleton organization GO:0045104 26 0.045
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.044
response to camp GO:0051591 14 0.044
spermatogenesis exchange of chromosomal proteins GO:0035093 4 0.044
negative regulation of cell growth GO:0030308 44 0.044
regulation of cell migration involved in sprouting angiogenesis GO:0090049 4 0.044
activation of adenylate cyclase activity GO:0007190 4 0.044
regulation of innate immune response GO:0045088 91 0.043
regulation of transcription by glucose GO:0046015 3 0.043
odontogenesis of dentin containing tooth GO:0042475 66 0.043
mesenchymal cell differentiation GO:0048762 107 0.043
regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway GO:1902235 11 0.043
maintenance of location GO:0051235 89 0.043
regulation of apoptotic signaling pathway GO:2001233 197 0.043
cyclic nucleotide mediated signaling GO:0019935 18 0.042
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.042
gastrulation GO:0007369 116 0.042
stem cell development GO:0048864 219 0.042
mesangial cell development GO:0072143 4 0.042
smoothened signaling pathway GO:0007224 105 0.042
cellular response to topologically incorrect protein GO:0035967 25 0.041
forebrain neuron development GO:0021884 30 0.041
regulation of kidney development GO:0090183 40 0.041
regulation of myeloid leukocyte differentiation GO:0002761 58 0.041
acetylcholine metabolic process GO:0008291 3 0.041
nucleoside phosphate metabolic process GO:0006753 338 0.041
negative regulation of immune system process GO:0002683 209 0.041
pattern specification involved in metanephros development GO:0072268 4 0.041
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.041
regulation of fat cell differentiation GO:0045598 81 0.041
oogenesis GO:0048477 56 0.040
oocyte axis specification GO:0007309 2 0.040
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.040
regulation of cellular amino acid metabolic process GO:0006521 5 0.040
cellular response to arsenic containing substance GO:0071243 4 0.040
cholesterol homeostasis GO:0042632 44 0.040
actin cytoskeleton organization GO:0030036 220 0.039
regulation of inositol trisphosphate biosynthetic process GO:0032960 3 0.039
cellular response to follicle stimulating hormone stimulus GO:0071372 1 0.039
regulation of intracellular ph GO:0051453 11 0.039
lipid biosynthetic process GO:0008610 179 0.039
lipid homeostasis GO:0055088 63 0.039
regulation of protein kinase activity GO:0045859 232 0.038
metanephric capsule development GO:0072213 1 0.038
bmp signaling pathway GO:0030509 93 0.038
regulation of vacuole organization GO:0044088 4 0.038
female somatic sex determination GO:0019101 1 0.038
mesangial cell differentiation GO:0072007 4 0.038
stress activated mapk cascade GO:0051403 80 0.038
bone remodeling GO:0046849 53 0.038
regulation of morphogenesis of a branching structure GO:0060688 53 0.038
learning or memory GO:0007611 148 0.038
negative regulation of glucokinase activity GO:0033132 4 0.038
cardiac chamber morphogenesis GO:0003206 93 0.037
mesenchyme development GO:0060485 152 0.037
pyramidal neuron differentiation GO:0021859 9 0.037
leukocyte proliferation GO:0070661 172 0.037
cellular response to starvation GO:0009267 57 0.037
pyramidal neuron development GO:0021860 8 0.037
regulation of cell growth GO:0001558 91 0.037
gonad development GO:0008406 141 0.037
axon ensheathment GO:0008366 76 0.037
female sex determination GO:0030237 1 0.037
divalent inorganic cation transport GO:0072511 178 0.036
oxalate transport GO:0019532 3 0.036
regulation of cell adhesion GO:0030155 154 0.036
endothelium development GO:0003158 45 0.036
nucleoside triphosphate metabolic process GO:0009141 230 0.036
membrane organization GO:0061024 245 0.036
positive regulation of transcription by glucose GO:0046016 3 0.036
negative regulation of neuron differentiation GO:0045665 101 0.036
nephrogenic mesenchyme development GO:0072076 3 0.036
cellular response to acid chemical GO:0071229 68 0.035
regulation of neuron projection development GO:0010975 169 0.035
mammary gland lobule development GO:0061377 22 0.035
negative regulation of erk1 and erk2 cascade GO:0070373 21 0.035
axon guidance GO:0007411 141 0.035
liver development GO:0001889 66 0.035
positive regulation of map kinase activity GO:0043406 84 0.035
regulation of vascular wound healing GO:0061043 2 0.035
regulation of cell cycle phase transition GO:1901987 77 0.035
cyclic nucleotide metabolic process GO:0009187 59 0.034
telencephalon development GO:0021537 186 0.034
positive regulation of defense response GO:0031349 124 0.034
cell fate determination GO:0001709 32 0.034
intermediate filament based process GO:0045103 27 0.034
negative regulation of cell development GO:0010721 169 0.034
positive regulation of bmp signaling pathway GO:0030513 23 0.034
dna packaging GO:0006323 30 0.034
blood vessel morphogenesis GO:0048514 285 0.034
regulation of cytokine production GO:0001817 266 0.034
apoptotic process involved in outflow tract morphogenesis GO:0003275 2 0.034
negative regulation of neuron projection development GO:0010977 50 0.034
glomerular visceral epithelial cell differentiation GO:0072112 10 0.034
cerebral cortex radially oriented cell migration GO:0021799 31 0.033
response to purine containing compound GO:0014074 28 0.033
carbohydrate biosynthetic process GO:0016051 74 0.033
ectoderm formation GO:0001705 3 0.033
sulfate transport GO:0008272 3 0.033
purine containing compound catabolic process GO:0072523 213 0.033
metanephric capsule formation GO:0072266 1 0.033
positive regulation of apoptotic process involved in morphogenesis GO:1902339 4 0.033
female gamete generation GO:0007292 74 0.033
cell fate commitment GO:0045165 210 0.033
cellular response to nutrient levels GO:0031669 64 0.033
nucleobase containing small molecule metabolic process GO:0055086 352 0.033
heterocycle catabolic process GO:0046700 280 0.032
negative regulation of mapk cascade GO:0043409 65 0.032
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.032
nucleoside phosphate catabolic process GO:1901292 222 0.032
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.032
bile acid secretion GO:0032782 2 0.032
regulation of detection of glucose GO:2000970 1 0.032
regulation of hormone secretion GO:0046883 88 0.032
transcription from rna polymerase iii promoter GO:0006383 3 0.032
monocarboxylic acid metabolic process GO:0032787 191 0.032
body fluid secretion GO:0007589 53 0.032
canonical wnt signaling pathway GO:0060070 130 0.032
cochlear nucleus development GO:0021747 4 0.032
insulin like growth factor receptor signaling pathway GO:0048009 21 0.031
receptor biosynthetic process GO:0032800 3 0.031
rap protein signal transduction GO:0032486 3 0.031

Cftr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.050
cancer DOID:162 0 0.037
organ system cancer DOID:0050686 0 0.034