IMP

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Mus musculus

4 genes annotated in mouse

Multi-species View

negative regulation of hexokinase activity

GO:1903300

Any process that stops, prevents or reduces the frequency, rate or extent of hexokinase activity.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of hexokinase activity"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of hexokinase activity" (in gray)

Name	Description	Probability	Func Analog Organism
Shh	sonic hedgehog	0.929
Eya1	eyes absent 1 homolog (Drosophila)	0.922
Tcfap2a	transcription factor AP-2, alpha	0.821
Pax2	paired box gene 2	0.805
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.700
Tbx1	T-box 1	0.643
Gli3	GLI-Kruppel family member GLI3	0.607
Hmx3	H6 homeobox 3	0.562
Bmp4	bone morphogenetic protein 4	0.558
Otx2	orthodenticle homolog 2 (Drosophila)	0.545
Fgfr2	fibroblast growth factor receptor 2	0.525
Foxa2	forkhead box A2	0.491
Foxc1	forkhead box C1	0.474	Mouse
Meox2	mesenchyme homeobox 2	0.451
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.439
Hoxa1	homeobox A1	0.379
En1	engrailed 1	0.335
Foxa1	forkhead box A1	0.328	Mouse
Pax9	paired box gene 9	0.309
Dlx5	distal-less homeobox 5	0.276
Nkx2-1	NK2 homeobox 1	0.263
Efnb2	ephrin B2	0.221
Fgfr3	fibroblast growth factor receptor 3	0.214
Pax8	paired box gene 8	0.211
Lmx1b	LIM homeobox transcription factor 1 beta	0.209
Gbx2	gastrulation brain homeobox 2	0.197
Vangl2	vang-like 2 (van gogh, Drosophila)	0.167
Psen1	presenilin 1	0.161
T	brachyury	0.157
Pitx2	paired-like homeodomain transcription factor 2	0.153
Jag1	jagged 1	0.152
Nog	noggin	0.148
Pax6	paired box gene 6	0.142
Gsc	goosecoid homeobox	0.140
Otx1	orthodenticle homolog 1 (Drosophila)	0.129
Chd7	chromodomain helicase DNA binding protein 7	0.127
Tbx10	T-box 10	0.126
Foxf2	forkhead box F2	0.111
Lmx1a	LIM homeobox transcription factor 1 alpha	0.099
Ctnnb1	catenin (cadherin associated protein), beta 1	0.092
Msx1	homeobox, msh-like 1	0.090
Sox2	SRY-box containing gene 2	0.089
Rdh10	retinol dehydrogenase 10 (all-trans)	0.084
Hoxa3	homeobox A3	0.076
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.073
Emx2	empty spiracles homolog 2 (Drosophila)	0.063
Emx1	empty spiracles homolog 1 (Drosophila)	0.062
Cldn4	claudin 4	0.062
Hand2	heart and neural crest derivatives expressed transcript 2	0.062
Alx1	ALX homeobox 1	0.057
Foxc2	forkhead box C2	0.057	Mouse
Fgf8	fibroblast growth factor 8	0.056
Pou4f2	POU domain, class 4, transcription factor 2	0.055
Tlx3	T-cell leukemia, homeobox 3	0.054
Zeb1	zinc finger E-box binding homeobox 1	0.054
Evx2	even skipped homeotic gene 2 homolog	0.052
Cdx1	caudal type homeobox 1	0.052
Hmx1	H6 homeobox 1	0.051
Hoxd3	homeobox D3	0.050
Neurog1	neurogenin 1	0.049
Pax3	paired box gene 3	0.048
Hoxa9	homeobox A9	0.048
Fgfrl1	fibroblast growth factor receptor-like 1	0.047
Cldn3	claudin 3	0.047
Rb1	retinoblastoma 1	0.045
Cftr	cystic fibrosis transmembrane conductance regulator homolog	0.045
Gdnf	glial cell line derived neurotrophic factor	0.045
Nkx3-2	NK3 homeobox 2	0.042
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.042
Rarb	retinoic acid receptor, beta	0.042
Pdx1	pancreatic and duodenal homeobox 1	0.042
Gli2	GLI-Kruppel family member GLI2	0.041
Hand1	heart and neural crest derivatives expressed transcript 1	0.040
Chrd	chordin	0.040
Prrx1	paired related homeobox 1	0.040
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.040
Hoxa2	homeobox A2	0.039
Bdnf	brain derived neurotrophic factor	0.038
Gck	glucokinase	0.036
Vax1	ventral anterior homeobox containing gene 1	0.036
Irx1	Iroquois related homeobox 1 (Drosophila)	0.035
Elf3	E74-like factor 3	0.035
Matn3	matrilin 3	0.033
Foxh1	forkhead box H1	0.032
Lhx1	LIM homeobox protein 1	0.031
Rarg	retinoic acid receptor, gamma	0.031
Cldn2	claudin 2	0.030
Tshz1	teashirt zinc finger family member 1	0.030
Calcr	calcitonin receptor	0.030
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.029
Tmem30b	transmembrane protein 30B	0.029
Fgf3	fibroblast growth factor 3	0.029
Sox9	SRY-box containing gene 9	0.028
Slc18a3	solute carrier family 18 (vesicular monoamine), member 3	0.027
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.027
Hoxd9	homeobox D9	0.027
Foxe3	forkhead box E3	0.027	Mouse
Hoxd11	homeobox D11	0.027
Zic1	zinc finger protein of the cerebellum 1	0.026
Pou4f3	POU domain, class 4, transcription factor 3	0.026
Dlx2	distal-less homeobox 2	0.025
Nr2f1	nuclear receptor subfamily 2, group F, member 1	0.025
Foxg1	forkhead box G1	0.025	Mouse
Fgfr1	fibroblast growth factor receptor 1	0.025
Lefty1	left right determination factor 1	0.025
Foxb1	forkhead box B1	0.025
Il25	interleukin 25	0.025
Klf5	Kruppel-like factor 5	0.024
Bmp7	bone morphogenetic protein 7	0.024
Dmrt3	doublesex and mab-3 related transcription factor 3	0.023
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.023
Hif1a	hypoxia inducible factor 1, alpha subunit	0.022
Atoh1	atonal homolog 1 (Drosophila)	0.022
Slc26a4	solute carrier family 26, member 4	0.022
Amh	anti-Mullerian hormone	0.022
Shroom1	shroom family member 1	0.022
Pthlh	parathyroid hormone-like peptide	0.022
Adcyap1	adenylate cyclase activating polypeptide 1	0.021
Hnf1b	HNF1 homeobox B	0.020
Fgf10	fibroblast growth factor 10	0.019
Adra2b	adrenergic receptor, alpha 2b	0.019
Ihh	Indian hedgehog	0.019
Atp6v1b1	ATPase, H+ transporting, lysosomal V1 subunit B1	0.018
Pitx3	paired-like homeodomain transcription factor 3	0.018
Hoxb5	homeobox B5	0.018
Nkx2-4	NK2 transcription factor related, locus 4 (Drosophila)	0.018
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.018
Epn3	epsin 3	0.017
Igfals	insulin-like growth factor binding protein, acid labile subunit	0.017
Etv2	ets variant gene 2	0.017
Cyp1b1	cytochrome P450, family 1, subfamily b, polypeptide 1	0.017
Msx2	homeobox, msh-like 2	0.017
Figla	folliculogenesis specific basic helix-loop-helix	0.017
Ush1g	Usher syndrome 1G homolog (human)	0.017
Hoxb13	homeobox B13	0.017
Ocln	occludin	0.017
Hmx2	H6 homeobox 2	0.016
BC021891	cDNA sequence BC021891	0.016
Cldn8	claudin 8	0.016
Golt1a	golgi transport 1 homolog A (S. cerevisiae)	0.016
Ntf3	neurotrophin 3	0.016
Flt4	FMS-like tyrosine kinase 4	0.016
Mnx1	motor neuron and pancreas homeobox 1	0.016
Cct6b	chaperonin containing Tcp1, subunit 6b (zeta)	0.016
Cdh1	cadherin 1	0.015
Nphs2	nephrosis 2 homolog, podocin (human)	0.015
Bnc1	basonuclin 1	0.015
Sall1	sal-like 1 (Drosophila)	0.015
Lyzl4	lysozyme-like 4	0.015
Wnt7a	wingless-related MMTV integration site 7A	0.015
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.015
Itih2	inter-alpha trypsin inhibitor, heavy chain 2	0.014
Phlda2	pleckstrin homology-like domain, family A, member 2	0.014
Hoxb8	homeobox B8	0.014
Marveld3	MARVEL (membrane-associating) domain containing 3	0.014
Cldn7	claudin 7	0.014
Tlx2	T-cell leukemia, homeobox 2	0.014
Ptpru	protein tyrosine phosphatase, receptor type, U	0.014
Sall3	sal-like 3 (Drosophila)	0.014
Wfdc2	WAP four-disulfide core domain 2	0.014
Egr4	early growth response 4	0.014
Mecom	MDS1 and EVI1 complex locus	0.014
BC057022	cDNA sequence BC057022	0.014
Hif3a	hypoxia inducible factor 3, alpha subunit	0.013
Fam83h	family with sequence similarity 83, member H	0.013
Tmprss2	transmembrane protease, serine 2	0.013
Vax2	ventral anterior homeobox containing gene 2	0.013
Crb3	crumbs homolog 3 (Drosophila)	0.013
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.013
Uncx	UNC homeobox	0.013
Emid2	EMI domain containing 2	0.013
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.013
Alox12	arachidonate 12-lipoxygenase	0.012
Kremen2	kringle containing transmembrane protein 2	0.012
Krt8	keratin 8	0.012
Gjb3	gap junction protein, beta 3	0.012
Esrp1	epithelial splicing regulatory protein 1	0.012
Hoxc6	homeobox C6	0.012
Bmper	BMP-binding endothelial regulator	0.012
Pbld1	phenazine biosynthesis-like protein domain containing 1	0.012
Prss42	protease, serine, 42	0.012
Rbmxl2	RNA binding motif protein, X-linked-like 2	0.012
Egfr	epidermal growth factor receptor	0.012
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.012
Hoxa5	homeobox A5	0.012
Bik	BCL2-interacting killer	0.012
Ly6g6d	lymphocyte antigen 6 complex, locus G6D	0.012
Foxq1	forkhead box Q1	0.012	Mouse
Barx1	BarH-like homeobox 1	0.012
Mycs	myc-like oncogene, s-myc protein	0.012
Sox3	SRY-box containing gene 3	0.012
Hoxa4	homeobox A4	0.012
Sftpb	surfactant associated protein B	0.012
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.012
Mogat1	monoacylglycerol O-acyltransferase 1	0.012
Ppp1cb	protein phosphatase 1, catalytic subunit, beta isoform	0.012
Ptch1	patched homolog 1	0.011
Col13a1	collagen, type XIII, alpha 1	0.011
Notch1	Notch gene homolog 1 (Drosophila)	0.011
Scrt2	scratch homolog 2, zinc finger protein (Drosophila)	0.011
Tulp2	tubby-like protein 2	0.011
BC021785	cDNA sequence BC021785	0.011
Efna5	ephrin A5	0.011
Krtap14	keratin associated protein 14	0.011
Dlx6	distal-less homeobox 6	0.011
Sncaip	synuclein, alpha interacting protein (synphilin)	0.011
Rnf186	ring finger protein 186	0.011
Pbx1	pre B-cell leukemia transcription factor 1	0.011
Foxd1	forkhead box D1	0.011	Mouse
Mn1	meningioma 1	0.010
Tbx15	T-box 15	0.010
Insm1	insulinoma-associated 1	0.010
Cnga3	cyclic nucleotide gated channel alpha 3	0.010
Crygn	crystallin, gamma N	0.010
Hoxd10	homeobox D10	0.010
G6pc2	glucose-6-phosphatase, catalytic, 2	0.010
Adm2	adrenomedullin 2	0.010
Zfp771	zinc finger protein 771	0.010
Pigr	polymeric immunoglobulin receptor	0.010
Drd1a	dopamine receptor D1A	0.010
Mfn2	mitofusin 2	0.010
Hes5	hairy and enhancer of split 5 (Drosophila)	0.010
Spdef	SAM pointed domain containing ets transcription factor	0.010
Cmtm8	CKLF-like MARVEL transmembrane domain containing 8	0.010