Mus musculus

134 known processes

Mapt

microtubule-associated protein tau

(Aliases: AW045860,AI413597,Tau,Mtapt)

Mapt biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of dendrite development GO:1900006 21 0.703
regulation of neuron differentiation GO:0045664 281 0.674
microtubule based process GO:0007017 236 0.579
transmembrane transport GO:0055085 412 0.513
cation transport GO:0006812 399 0.501
establishment of organelle localization GO:0051656 122 0.494
regulation of ion transport GO:0043269 215 0.468
negative regulation of cellular component organization GO:0051129 194 0.466
microtubule cytoskeleton organization GO:0000226 157 0.422
mitotic cell cycle GO:0000278 195 0.420
Mouse
membrane tubulation GO:0097320 4 0.401
meiotic cell cycle GO:0051321 122 0.400
regulation of cell projection organization GO:0031344 206 0.385
positive regulation of nervous system development GO:0051962 221 0.381
synaptic transmission GO:0007268 329 0.316
regulation of neuron projection development GO:0010975 169 0.313
endomembrane system organization GO:0010256 147 0.309
axon guidance GO:0007411 141 0.308
inorganic ion transmembrane transport GO:0098660 234 0.306
mitotic cell cycle process GO:1903047 159 0.302
Mouse
axonogenesis GO:0007409 274 0.302
regulation of membrane potential GO:0042391 192 0.298
positive regulation of cell projection organization GO:0031346 95 0.294
regulation of cellular component size GO:0032535 121 0.291
positive regulation of neuron projection development GO:0010976 79 0.279
organophosphate catabolic process GO:0046434 232 0.278
membrane organization GO:0061024 245 0.268
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.257
synapse organization GO:0050808 125 0.253
ribonucleoside triphosphate catabolic process GO:0009203 199 0.251
nucleoside catabolic process GO:0009164 206 0.250
nucleoside triphosphate metabolic process GO:0009141 230 0.235
divalent inorganic cation transport GO:0072511 178 0.226
regulation of ion transmembrane transporter activity GO:0032412 54 0.222
actin cytoskeleton organization GO:0030036 220 0.222
purine nucleoside triphosphate metabolic process GO:0009144 226 0.221
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.216
regulation of ion transmembrane transport GO:0034765 119 0.215
sodium ion transmembrane transport GO:0035725 49 0.214
organonitrogen compound catabolic process GO:1901565 264 0.206
organelle localization GO:0051640 179 0.204
regulation of actin cytoskeleton organization GO:0032956 84 0.198
mitotic cytokinesis GO:0000281 4 0.190
plasma membrane organization GO:0007009 90 0.186
protein localization to plasma membrane GO:0072659 57 0.184
rho protein signal transduction GO:0007266 32 0.184
organic anion transport GO:0015711 137 0.184
purine nucleoside catabolic process GO:0006152 205 0.182
cell fate commitment GO:0045165 210 0.177
hindbrain development GO:0030902 128 0.175
actin polymerization or depolymerization GO:0008154 54 0.175
negative regulation of molecular function GO:0044092 258 0.174
macromolecule catabolic process GO:0009057 281 0.174
ion transmembrane transport GO:0034220 361 0.172
skin development GO:0043588 220 0.169
forebrain development GO:0030900 302 0.164
nucleotide catabolic process GO:0009166 217 0.164
carbohydrate derivative catabolic process GO:1901136 231 0.162
neuron projection extension GO:1990138 64 0.162
cerebral cortex development GO:0021987 86 0.162
organic cyclic compound catabolic process GO:1901361 295 0.154
aromatic compound catabolic process GO:0019439 286 0.152
negative regulation of nervous system development GO:0051961 156 0.151
cellular amino acid metabolic process GO:0006520 103 0.150
regulation of protein localization GO:0032880 231 0.150
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.150
protein polymerization GO:0051258 57 0.149
Human
meiotic cell cycle process GO:1903046 77 0.149
nuclear division GO:0000280 158 0.146
chemotaxis GO:0006935 247 0.145
cation transmembrane transport GO:0098655 266 0.145
positive regulation of cell death GO:0010942 224 0.145
synaptic vesicle transport GO:0048489 57 0.144
nucleoside metabolic process GO:0009116 246 0.140
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.136
positive regulation of growth GO:0045927 104 0.136
regulation of metal ion transport GO:0010959 106 0.136
small gtpase mediated signal transduction GO:0007264 97 0.135
regulation of transmembrane transport GO:0034762 128 0.135
glycosyl compound catabolic process GO:1901658 206 0.134
meiotic nuclear division GO:0007126 115 0.131
ribonucleoside catabolic process GO:0042454 206 0.130
telencephalon development GO:0021537 186 0.130
calcium ion transport GO:0006816 159 0.129
regulation of cellular ketone metabolic process GO:0010565 66 0.128
negative regulation of cell development GO:0010721 169 0.128
cognition GO:0050890 149 0.126
purine nucleoside triphosphate catabolic process GO:0009146 203 0.125
purine nucleoside metabolic process GO:0042278 241 0.122
protein localization to membrane GO:0072657 108 0.120
glycosyl compound metabolic process GO:1901657 246 0.120
neuron projection guidance GO:0097485 141 0.120
camera type eye development GO:0043010 266 0.119
anion transport GO:0006820 177 0.119
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.116
purine ribonucleotide catabolic process GO:0009154 208 0.115
negative regulation of neuron differentiation GO:0045665 101 0.115
ribonucleoside metabolic process GO:0009119 245 0.114
organelle fission GO:0048285 170 0.114
ubiquitin dependent protein catabolic process GO:0006511 129 0.113
nucleoside triphosphate catabolic process GO:0009143 205 0.113
intracellular protein transport GO:0006886 204 0.112
regulation of organelle organization GO:0033043 289 0.111
Human
establishment of synaptic vesicle localization GO:0097480 57 0.111
learning or memory GO:0007611 148 0.110
dephosphorylation GO:0016311 129 0.109
regulation of protein complex assembly GO:0043254 83 0.107
Human
cellular ketone metabolic process GO:0042180 84 0.107
negative regulation of neuron projection development GO:0010977 50 0.106
inorganic cation transmembrane transport GO:0098662 207 0.106
regulation of cell cycle GO:0051726 281 0.104
glial cell differentiation GO:0010001 131 0.103
axon cargo transport GO:0008088 33 0.103
nucleoside phosphate catabolic process GO:1901292 222 0.102
regulation of synaptic plasticity GO:0048167 87 0.101
regulation of cell motility GO:2000145 236 0.101
heterocycle catabolic process GO:0046700 280 0.101
establishment of vesicle localization GO:0051650 81 0.099
posttranscriptional regulation of gene expression GO:0010608 155 0.098
synaptic vesicle localization GO:0097479 59 0.098
vesicle localization GO:0051648 86 0.098
regulation of vesicle mediated transport GO:0060627 139 0.098
endocytosis GO:0006897 168 0.095
gtp metabolic process GO:0046039 144 0.094
regulation of cellular amine metabolic process GO:0033238 20 0.093
regulation of endocytosis GO:0030100 69 0.093
actin filament polymerization GO:0030041 44 0.093
negative regulation of protein metabolic process GO:0051248 282 0.093
neurotransmitter transport GO:0006836 76 0.093
positive regulation of apoptotic process GO:0043065 217 0.092
protein catabolic process GO:0030163 221 0.090
nucleobase containing small molecule metabolic process GO:0055086 352 0.089
stem cell differentiation GO:0048863 268 0.089
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.088
regulation of cytoskeleton organization GO:0051493 122 0.087
Human
purine ribonucleoside catabolic process GO:0046130 205 0.086
purine ribonucleotide metabolic process GO:0009150 290 0.086
eye photoreceptor cell development GO:0042462 31 0.086
action potential GO:0001508 78 0.086
ras protein signal transduction GO:0007265 77 0.085
heart morphogenesis GO:0003007 178 0.085
nucleoside phosphate metabolic process GO:0006753 338 0.085
positive regulation of organelle organization GO:0010638 128 0.084
Human
regulation of actin filament based process GO:0032970 99 0.084
ribose phosphate metabolic process GO:0019693 291 0.083
regulation of intracellular transport GO:0032386 159 0.083
divalent metal ion transport GO:0070838 172 0.082
cellular response to growth factor stimulus GO:0071363 197 0.082
response to organonitrogen compound GO:0010243 246 0.081
regulation of anatomical structure size GO:0090066 178 0.081
learning GO:0007612 98 0.080
synapse assembly GO:0007416 56 0.080
potassium ion homeostasis GO:0055075 4 0.080
regulation of neurotransmitter levels GO:0001505 87 0.079
olfactory learning GO:0008355 2 0.079
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.078
cellular potassium ion transport GO:0071804 43 0.078
neuromuscular process controlling balance GO:0050885 59 0.076
sodium ion export GO:0071436 2 0.076
photoreceptor cell differentiation GO:0046530 52 0.076
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.076
nucleotide metabolic process GO:0009117 332 0.076
positive regulation of cell development GO:0010720 237 0.075
epidermis development GO:0008544 187 0.075
regulation of transporter activity GO:0032409 57 0.074
regulation of mitotic cell cycle GO:0007346 126 0.073
ribonucleotide catabolic process GO:0009261 208 0.073
purine containing compound catabolic process GO:0072523 213 0.072
gland development GO:0048732 330 0.072
negative regulation of cellular protein metabolic process GO:0032269 247 0.071
regulation of neuron death GO:1901214 134 0.070
ensheathment of neurons GO:0007272 76 0.070
ribonucleoside triphosphate metabolic process GO:0009199 220 0.070
multicellular organismal signaling GO:0035637 91 0.070
neuromuscular process GO:0050905 99 0.069
pallium development GO:0021543 120 0.069
developmental cell growth GO:0048588 84 0.067
neuronal action potential GO:0019228 54 0.067
cell adhesion GO:0007155 329 0.066
negative regulation of cell cycle GO:0045786 123 0.066
modification dependent macromolecule catabolic process GO:0043632 133 0.065
regulation of cellular component biogenesis GO:0044087 181 0.065
Human
regulation of actin filament polymerization GO:0030833 38 0.064
regulation of actin polymerization or depolymerization GO:0008064 45 0.064
positive regulation of ion transmembrane transporter activity GO:0032414 15 0.063
negative regulation of ion transport GO:0043271 28 0.063
ribonucleotide metabolic process GO:0009259 291 0.063
peripheral nervous system neuron axonogenesis GO:0048936 3 0.062
protein oligomerization GO:0051259 67 0.062
microtubule based movement GO:0007018 84 0.062
germ cell development GO:0007281 185 0.062
regulation of purine nucleotide catabolic process GO:0033121 122 0.061
cell growth GO:0016049 130 0.061
positive regulation of protein complex assembly GO:0031334 45 0.060
Human
positive regulation of cell cycle GO:0045787 92 0.058
limbic system development GO:0021761 72 0.058
wnt signaling pathway GO:0016055 188 0.058
organelle assembly GO:0070925 177 0.057
modification dependent protein catabolic process GO:0019941 133 0.057
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.057
extracellular matrix organization GO:0030198 147 0.056
mrna metabolic process GO:0016071 84 0.056
primary neural tube formation GO:0014020 95 0.056
purine nucleotide metabolic process GO:0006163 302 0.055
positive regulation of cytoskeleton organization GO:0051495 49 0.054
Human
epithelial cell development GO:0002064 159 0.054
regionalization GO:0003002 337 0.054
sensory perception GO:0007600 245 0.054
sensory organ morphogenesis GO:0090596 242 0.054
cell division GO:0051301 120 0.054
gtp catabolic process GO:0006184 143 0.054
positive regulation of cellular component biogenesis GO:0044089 94 0.053
Human
engulfment of apoptotic cell GO:0043652 3 0.053
sodium ion transport GO:0006814 73 0.053
potassium ion transmembrane transport GO:0071805 43 0.052
guanosine containing compound metabolic process GO:1901068 144 0.052
developmental growth involved in morphogenesis GO:0060560 138 0.052
asymmetric neuroblast division GO:0055059 1 0.051
transmission of nerve impulse GO:0019226 76 0.051
purine nucleotide catabolic process GO:0006195 211 0.050
regulation of hydrolase activity GO:0051336 246 0.050
neuron apoptotic process GO:0051402 142 0.050
regulation of sodium ion transmembrane transporter activity GO:2000649 9 0.050
negative regulation of axon extension GO:0030517 19 0.050
regulation of cellular response to stress GO:0080135 159 0.050
extracellular structure organization GO:0043062 148 0.049
regulation of establishment of protein localization GO:0070201 181 0.049
protein ubiquitination GO:0016567 171 0.049
positive regulation of programmed cell death GO:0043068 218 0.049
embryonic organ morphogenesis GO:0048562 276 0.048
negative regulation of intracellular signal transduction GO:1902532 167 0.048
regulation of calcium ion transport GO:0051924 69 0.048
stem cell development GO:0048864 219 0.048
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.048
regulation of body fluid levels GO:0050878 162 0.047
regulation of cell migration GO:0030334 219 0.047
protein modification by small protein conjugation or removal GO:0070647 207 0.047
rna processing GO:0006396 105 0.047
gliogenesis GO:0042063 141 0.047
male meiosis GO:0007140 37 0.047
regulation of endopeptidase activity GO:0052548 89 0.046
photoreceptor cell development GO:0042461 40 0.046
cellular protein complex assembly GO:0043623 116 0.046
Human
male gamete generation GO:0048232 285 0.046
renal system development GO:0072001 225 0.045
sa node cell to atrial cardiac muscle cell signalling GO:0086018 4 0.045
regulation of sodium ion transmembrane transport GO:1902305 9 0.044
translation GO:0006412 93 0.044
immune effector process GO:0002252 321 0.044
actin filament organization GO:0007015 113 0.044
regulation of actin filament length GO:0030832 45 0.044
multi organism behavior GO:0051705 62 0.043
notch signaling pathway GO:0007219 71 0.043
single organismal cell cell adhesion GO:0016337 131 0.043
regulation of translation GO:0006417 71 0.043
negative regulation of cell projection organization GO:0031345 56 0.043
calcium ion transmembrane transport GO:0070588 85 0.042
protein homooligomerization GO:0051260 43 0.041
negative regulation of organelle organization GO:0010639 90 0.041
protein modification by small protein conjugation GO:0032446 187 0.041
cerebral cortex radially oriented cell migration GO:0021799 31 0.041
cell substrate adhesion GO:0031589 130 0.041
cytoplasmic transport GO:0016482 234 0.041
cell type specific apoptotic process GO:0097285 268 0.041
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.041
asymmetric stem cell division GO:0098722 3 0.040
positive regulation of actin filament polymerization GO:0030838 26 0.040
adult behavior GO:0030534 135 0.040
telencephalon cell migration GO:0022029 55 0.040
regulation of proteolysis GO:0030162 164 0.040
positive regulation of neuron differentiation GO:0045666 141 0.040
neural tube development GO:0021915 160 0.040
neural tube formation GO:0001841 108 0.040
negative regulation of protein kinase activity by regulation of protein phosphorylation GO:0044387 2 0.039
regulation of protein catabolic process GO:0042176 108 0.039
regulation of intracellular protein transport GO:0033157 82 0.039
spermatogenesis GO:0007283 284 0.039
regulation of cell cycle process GO:0010564 160 0.039
tube closure GO:0060606 91 0.039
positive regulation of ion transmembrane transport GO:0034767 24 0.039
cellular macromolecule catabolic process GO:0044265 206 0.038
brain morphogenesis GO:0048854 32 0.038
t cell proliferation GO:0042098 120 0.038
proteasomal protein catabolic process GO:0010498 98 0.038
neurotransmitter uptake GO:0001504 14 0.037
regulation of gtp catabolic process GO:0033124 113 0.037
regulation of cellular catabolic process GO:0031329 242 0.037
Human
response to light stimulus GO:0009416 135 0.037
embryonic epithelial tube formation GO:0001838 130 0.037
lateral inhibition GO:0046331 1 0.037
cardiac muscle contraction GO:0060048 32 0.037
regulation of protein targeting GO:1903533 61 0.037
cellular protein catabolic process GO:0044257 155 0.037
metal ion homeostasis GO:0055065 189 0.037
potassium ion transport GO:0006813 52 0.037
cytokinesis GO:0000910 17 0.036
regulation of cytoplasmic transport GO:1903649 112 0.036
stem cell maintenance GO:0019827 130 0.036
regulation of mapk cascade GO:0043408 248 0.036
negative regulation of immune system process GO:0002683 209 0.036
guanosine containing compound catabolic process GO:1901069 144 0.035
morphogenesis of a polarized epithelium GO:0001738 37 0.035
response to radiation GO:0009314 165 0.035
hematopoietic progenitor cell differentiation GO:0002244 143 0.035
blood circulation GO:0008015 195 0.035
cerebellar purkinje cell layer development GO:0021680 26 0.034
homeostasis of number of cells GO:0048872 210 0.034
metencephalon development GO:0022037 89 0.034
cytokinetic process GO:0032506 2 0.034
establishment of protein localization to plasma membrane GO:0090002 34 0.034
associative learning GO:0008306 61 0.033
cardiac muscle tissue development GO:0048738 130 0.033
heart contraction GO:0060047 93 0.033
protein localization to organelle GO:0033365 185 0.033
multicellular organism growth GO:0035264 161 0.033
negative regulation of transferase activity GO:0051348 85 0.033
hippocampus development GO:0021766 52 0.033
regulation of potassium ion transmembrane transporter activity GO:1901016 7 0.032
regulation of protein stability GO:0031647 52 0.032
negative regulation of sodium ion transmembrane transport GO:1902306 1 0.032
adaptive immune response GO:0002250 155 0.032
cellular nitrogen compound catabolic process GO:0044270 280 0.032
peptidyl amino acid modification GO:0018193 336 0.032
spindle assembly involved in meiosis GO:0090306 4 0.032
regulation of cell adhesion GO:0030155 154 0.032
neuron migration GO:0001764 122 0.031
mechanoreceptor differentiation GO:0042490 67 0.031
muscle system process GO:0003012 141 0.031
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.031
regulation of nucleoside metabolic process GO:0009118 130 0.031
single organism cell adhesion GO:0098602 156 0.031
protein targeting GO:0006605 143 0.031
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.030
morphogenesis of embryonic epithelium GO:0016331 159 0.030
appendage development GO:0048736 166 0.030
positive regulation of cell cycle process GO:0090068 61 0.030
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.030
multicellular organismal homeostasis GO:0048871 164 0.030
negative regulation of sodium ion transmembrane transporter activity GO:2000650 1 0.030
spermatid differentiation GO:0048515 115 0.030
response to temperature stimulus GO:0009266 55 0.030
canonical wnt signaling pathway GO:0060070 130 0.029
oxidation reduction process GO:0055114 342 0.029
sodium ion export from cell GO:0036376 1 0.029
myelination in peripheral nervous system GO:0022011 19 0.029
negative regulation of endocytosis GO:0045806 12 0.029
exocytosis GO:0006887 121 0.029
regulation of rho protein signal transduction GO:0035023 71 0.029
regulation of cellular amino acid metabolic process GO:0006521 5 0.029
regulation of receptor activity GO:0010469 41 0.029
apoptotic mitochondrial changes GO:0008637 48 0.029
regulation of system process GO:0044057 200 0.029
eye photoreceptor cell differentiation GO:0001754 41 0.029
mitotic nuclear division GO:0007067 48 0.029
auditory receptor cell differentiation GO:0042491 37 0.029
rac protein signal transduction GO:0016601 13 0.029
response to acid chemical GO:0001101 111 0.028
cerebral cortex cell migration GO:0021795 44 0.028
gene silencing GO:0016458 38 0.028
female gamete generation GO:0007292 74 0.028
positive regulation of protein export from nucleus GO:0046827 4 0.028
regulation of nucleotide catabolic process GO:0030811 122 0.028
myeloid cell differentiation GO:0030099 233 0.028
response to growth factor GO:0070848 198 0.028
axon ensheathment GO:0008366 76 0.028
peptidyl tyrosine modification GO:0018212 145 0.028
cell cell junction assembly GO:0007043 27 0.028
spermatid development GO:0007286 108 0.028
ventricular cardiac muscle cell action potential GO:0086005 4 0.028
establishment of protein localization to membrane GO:0090150 54 0.027
regulation of protein binding GO:0043393 60 0.027
regulation of exit from mitosis GO:0007096 1 0.027
innate immune response GO:0045087 157 0.027
regulation of microtubule based process GO:0032886 52 0.027
peripheral nervous system development GO:0007422 53 0.027
regulation of retina development in camera type eye GO:1902866 3 0.027
positive regulation of sodium ion transmembrane transport GO:1902307 4 0.027
dendrite development GO:0016358 115 0.026
Mouse
tube formation GO:0035148 140 0.026
establishment or maintenance of cell polarity GO:0007163 86 0.026
Mouse
hair cell differentiation GO:0035315 40 0.026
behavioral response to nutrient GO:0051780 1 0.026
purine containing compound metabolic process GO:0072521 311 0.026
negative regulation of phosphorylation GO:0042326 166 0.026
dendritic spine morphogenesis GO:0060997 22 0.025
regulation of neuron apoptotic process GO:0043523 122 0.025
cellular response to lipid GO:0071396 145 0.025
cell cell junction organization GO:0045216 72 0.025
inter male aggressive behavior GO:0002121 3 0.025
body fluid secretion GO:0007589 53 0.025
positive regulation of hydrolase activity GO:0051345 148 0.024
spindle organization GO:0007051 28 0.024
Mouse
synaptic vesicle endocytosis GO:0048488 19 0.024
positive regulation of transmembrane transport GO:0034764 29 0.024
divalent inorganic cation homeostasis GO:0072507 138 0.024
positive regulation of protein phosphorylation GO:0001934 242 0.024
regulation of protein kinase activity GO:0045859 232 0.024
mitochondrion organization GO:0007005 134 0.024
regulation of heart contraction GO:0008016 77 0.024
response to osmotic stress GO:0006970 21 0.024
cardiac cell fate specification GO:0060912 2 0.024
regulation of sodium ion transport GO:0002028 29 0.023
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.023
regulation of jnk cascade GO:0046328 62 0.023
regulation of dendritic spine morphogenesis GO:0061001 17 0.023
localization within membrane GO:0051668 4 0.023
regulation of auditory receptor cell differentiation GO:0045607 4 0.023
negative regulation of cell growth GO:0030308 44 0.023
neural precursor cell proliferation GO:0061351 121 0.023
leukocyte differentiation GO:0002521 342 0.023
regulation of protein maturation GO:1903317 96 0.023
retinal cone cell development GO:0046549 8 0.023
regulation of cell substrate adhesion GO:0010810 73 0.023
cation homeostasis GO:0055080 212 0.023
regulation of notch signaling pathway GO:0008593 35 0.023
positive regulation of transporter activity GO:0032411 17 0.023
central nervous system neuron differentiation GO:0021953 162 0.023
blood vessel morphogenesis GO:0048514 285 0.022
protein targeting to membrane GO:0006612 20 0.022
cellular response to organonitrogen compound GO:0071417 145 0.022
peptidyl serine modification GO:0018209 83 0.022
mrna processing GO:0006397 63 0.022
negative regulation of calcium ion transport GO:0051926 9 0.022
muscle cell differentiation GO:0042692 261 0.022
bone development GO:0060348 120 0.022
regulation of gliogenesis GO:0014013 50 0.022
positive regulation of gliogenesis GO:0014015 27 0.022
covalent chromatin modification GO:0016569 163 0.022
calcium mediated signaling GO:0019722 46 0.022
anatomical structure homeostasis GO:0060249 145 0.022
positive regulation of cellular amine metabolic process GO:0033240 5 0.022
heart process GO:0003015 94 0.022
regulation of synapse structural plasticity GO:0051823 4 0.022
regulation of striated muscle cell differentiation GO:0051153 81 0.021
multi multicellular organism process GO:0044706 109 0.021
positive regulation of potassium ion transport GO:0043268 3 0.021
t cell activation GO:0042110 289 0.021
salivary gland development GO:0007431 37 0.021
l glutamate transport GO:0015813 16 0.021
cellular homeostasis GO:0019725 240 0.021
maintenance of presynaptic active zone structure GO:0048790 1 0.021
cardiocyte differentiation GO:0035051 87 0.021
neuron death GO:0070997 154 0.021
exocrine system development GO:0035272 45 0.021
second messenger mediated signaling GO:0019932 73 0.021
regulation of cell growth GO:0001558 91 0.021
regulation of apoptotic signaling pathway GO:2001233 197 0.021
regulation of protein processing GO:0070613 96 0.021
dna metabolic process GO:0006259 303 0.021
positive regulation of necrotic cell death GO:0010940 1 0.021
establishment of endothelial blood brain barrier GO:0014045 3 0.021
regulation of neuronal synaptic plasticity GO:0048168 30 0.021
macromolecule methylation GO:0043414 120 0.021
calcium ion homeostasis GO:0055074 127 0.021
blastocyst growth GO:0001832 23 0.021
multicellular organismal aging GO:0010259 24 0.020
molting cycle GO:0042303 90 0.020
positive regulation of cell motility GO:2000147 116 0.020
hatching GO:0035188 4 0.020
nucleocytoplasmic transport GO:0006913 139 0.020
cerebellar cortex morphogenesis GO:0021696 32 0.020
positive regulation of nucleotide catabolic process GO:0030813 88 0.020
regulation of protein transport GO:0051223 163 0.020
protein localization to nucleus GO:0034504 121 0.020
rap protein signal transduction GO:0032486 3 0.020
blastocyst development GO:0001824 80 0.020
transition metal ion homeostasis GO:0055076 54 0.020
actin mediated cell contraction GO:0070252 15 0.020
cellular response to acid chemical GO:0071229 68 0.020
leukocyte proliferation GO:0070661 172 0.020
actin filament bundle assembly GO:0051017 40 0.020
positive regulation of synapse assembly GO:0051965 18 0.020
dicarboxylic acid transport GO:0006835 29 0.020
regulation of ras gtpase activity GO:0032318 88 0.020
digestive tract development GO:0048565 190 0.019
nuclear transport GO:0051169 139 0.019
cellular response to cytokine stimulus GO:0071345 189 0.019
compartment pattern specification GO:0007386 4 0.019
sensory system development GO:0048880 3 0.019
circulatory system process GO:0003013 197 0.019
positive regulation of cell migration GO:0030335 109 0.019
inner ear receptor cell differentiation GO:0060113 61 0.019
negative regulation of protein modification process GO:0031400 163 0.019
regulation of nucleocytoplasmic transport GO:0046822 73 0.019
inclusion body assembly GO:0070841 3 0.019
developmental maturation GO:0021700 193 0.019
cellular amide metabolic process GO:0043603 58 0.018
muscle contraction GO:0006936 101 0.018
cellular response to peptide hormone stimulus GO:0071375 92 0.018

Mapt disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.340
Human
brain disease DOID:936 0 0.340
Human
disease of anatomical entity DOID:7 0 0.340
Human
nervous system disease DOID:863 0 0.340
Human
neurodegenerative disease DOID:1289 0 0.058
Human
muscular disease DOID:0080000 0 0.040
musculoskeletal system disease DOID:17 0 0.040
muscle tissue disease DOID:66 0 0.040
neuropathy DOID:870 0 0.022
neuromuscular disease DOID:440 0 0.021