Mus musculus

48 known processes

Clu

clusterin

(Aliases: Cli,Sugp-2,AI893575,Sgp2,ApoJ,Sgp-2,D14Ucla3,SP-40)

Clu biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell adhesion GO:0007155 329 0.193
extracellular structure organization GO:0043062 148 0.144
copper ion homeostasis GO:0055070 9 0.136
cellular amino acid metabolic process GO:0006520 103 0.133
cellular amine metabolic process GO:0044106 44 0.123
regulation of cellular amino acid metabolic process GO:0006521 5 0.118
cytokine production GO:0001816 319 0.105
Human
inositol phosphate mediated signaling GO:0048016 13 0.102
mapk cascade GO:0000165 281 0.101
regulation of peptidase activity GO:0052547 96 0.098
regulation of cellular ketone metabolic process GO:0010565 66 0.097
negative regulation of molecular function GO:0044092 258 0.094
regulation of protein kinase activity GO:0045859 232 0.089
Human
regulation of cellular amine metabolic process GO:0033238 20 0.081
amine metabolic process GO:0009308 45 0.081
apoptotic signaling pathway GO:0097190 306 0.080
Human
single organismal cell cell adhesion GO:0016337 131 0.079
sterol metabolic process GO:0016125 58 0.079
regulation of defense response GO:0031347 233 0.079
locomotory behavior GO:0007626 195 0.078
regulation of kinase activity GO:0043549 249 0.078
Human
alcohol metabolic process GO:0006066 116 0.077
inflammatory response GO:0006954 244 0.077
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.076
chemotaxis GO:0006935 247 0.072
negative regulation of protein metabolic process GO:0051248 282 0.072
Human
cellular lipid metabolic process GO:0044255 323 0.070
urogenital system development GO:0001655 261 0.070
cholesterol metabolic process GO:0008203 56 0.069
negative regulation of cell proliferation GO:0008285 296 0.065
cellular copper ion homeostasis GO:0006878 8 0.063
regulation of protein maturation GO:1903317 96 0.063
regulation of mapk cascade GO:0043408 248 0.062
organic hydroxy compound metabolic process GO:1901615 203 0.059
lipid biosynthetic process GO:0008610 179 0.057
calcineurin nfat signaling cascade GO:0033173 8 0.057
regulation of inflammatory response GO:0050727 147 0.055
hindbrain development GO:0030902 128 0.055
cellular ketone metabolic process GO:0042180 84 0.054
activation of immune response GO:0002253 138 0.054
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.053
regulation of proteolysis GO:0030162 164 0.052
Human
response to organic cyclic compound GO:0014070 198 0.052
neuron projection guidance GO:0097485 141 0.052
positive regulation of neuron projection development GO:0010976 79 0.052
regulation of hydrolase activity GO:0051336 246 0.052
cellular homeostasis GO:0019725 240 0.051
negative regulation of cell development GO:0010721 169 0.050
negative regulation of cellular protein metabolic process GO:0032269 247 0.049
regulation of beta amyloid clearance GO:1900221 1 0.048
Human
oxidation reduction process GO:0055114 342 0.048
protein maturation GO:0051604 176 0.047
spermatid differentiation GO:0048515 115 0.047
leukocyte differentiation GO:0002521 342 0.046
regulation of calcineurin nfat signaling cascade GO:0070884 5 0.046
male gamete generation GO:0048232 285 0.046
regulation of cell projection organization GO:0031344 206 0.046
positive regulation of nervous system development GO:0051962 221 0.045
immune effector process GO:0002252 321 0.045
gland development GO:0048732 330 0.045
positive regulation of programmed cell death GO:0043068 218 0.045
Human
regulation of protein processing GO:0070613 96 0.044
neuron death GO:0070997 154 0.044
negative regulation of immune system process GO:0002683 209 0.044
regulation of cell activation GO:0050865 289 0.043
regulation of neuron differentiation GO:0045664 281 0.043
negative regulation of nervous system development GO:0051961 156 0.041
posttranscriptional regulation of gene expression GO:0010608 155 0.041
Human
spermatogenesis GO:0007283 284 0.041
regulation of endopeptidase activity GO:0052548 89 0.039
cell recognition GO:0008037 83 0.039
muscle tissue development GO:0060537 308 0.039
transmembrane transport GO:0055085 412 0.039
nucleotide metabolic process GO:0009117 332 0.038
response to steroid hormone GO:0048545 56 0.038
regulation of neuron projection development GO:0010975 169 0.038
small molecule biosynthetic process GO:0044283 132 0.038
t cell activation GO:0042110 289 0.037
cell type specific apoptotic process GO:0097285 268 0.037
carboxylic acid biosynthetic process GO:0046394 86 0.037
acylglycerol metabolic process GO:0006639 55 0.037
cation homeostasis GO:0055080 212 0.036
negative regulation of intracellular signal transduction GO:1902532 167 0.036
Human
positive regulation of apoptotic process GO:0043065 217 0.036
Human
regulation of cytokine production GO:0001817 266 0.035
Human
striated muscle tissue development GO:0014706 293 0.035
cognition GO:0050890 149 0.035
steroid metabolic process GO:0008202 119 0.035
regulation of response to wounding GO:1903034 189 0.035
negative regulation of neuron death GO:1901215 98 0.035
negative regulation of endopeptidase activity GO:0010951 44 0.034
response to radiation GO:0009314 165 0.034
positive regulation of protein modification process GO:0031401 299 0.034
Human
regulation of membrane potential GO:0042391 192 0.034
negative regulation of hydrolase activity GO:0051346 71 0.034
molting cycle GO:0042303 90 0.033
regulation of cellular catabolic process GO:0031329 242 0.033
Human
negative regulation of neuron differentiation GO:0045665 101 0.033
epidermis development GO:0008544 187 0.032
positive regulation of cellular amine metabolic process GO:0033240 5 0.031
single organism cell adhesion GO:0098602 156 0.031
positive regulation of transferase activity GO:0051347 167 0.031
Human
response to peptide GO:1901652 136 0.031
potassium ion transport GO:0006813 52 0.031
developmental maturation GO:0021700 193 0.031
respiratory system development GO:0060541 190 0.031
response to oxidative stress GO:0006979 123 0.031
negative regulation of proteolysis GO:0045861 74 0.031
ensheathment of neurons GO:0007272 76 0.031
Human
muscle system process GO:0003012 141 0.030
feeding behavior GO:0007631 62 0.030
positive regulation of cell projection organization GO:0031346 95 0.030
negative regulation of phosphate metabolic process GO:0045936 184 0.030
positive regulation of mapk cascade GO:0043410 170 0.030
protein processing GO:0016485 163 0.030
regulation of lymphocyte activation GO:0051249 240 0.030
sensory organ morphogenesis GO:0090596 242 0.030
extracellular matrix organization GO:0030198 147 0.029
multicellular organismal signaling GO:0035637 91 0.029
purine containing compound metabolic process GO:0072521 311 0.029
multicellular organism growth GO:0035264 161 0.028
positive regulation of growth GO:0045927 104 0.028
response to inorganic substance GO:0010035 96 0.028
neuron apoptotic process GO:0051402 142 0.028
glycerolipid metabolic process GO:0046486 122 0.028
cell growth GO:0016049 130 0.028
cellular response to growth factor stimulus GO:0071363 197 0.028
regulation of cell motility GO:2000145 236 0.027
skin development GO:0043588 220 0.027
macromolecule catabolic process GO:0009057 281 0.027
Human
monocarboxylic acid metabolic process GO:0032787 191 0.027
purine nucleotide metabolic process GO:0006163 302 0.027
glycosyl compound catabolic process GO:1901658 206 0.026
wound healing GO:0042060 157 0.026
organ regeneration GO:0031100 2 0.026
regulation of hormone levels GO:0010817 211 0.026
cell cell adhesion GO:0098609 41 0.026
regulation of cell migration GO:0030334 219 0.026
negative regulation of phosphorus metabolic process GO:0010563 184 0.026
sensory perception GO:0007600 245 0.026
cellular modified amino acid metabolic process GO:0006575 63 0.026
peptidyl tyrosine phosphorylation GO:0018108 143 0.026
negative regulation of protein maturation GO:1903318 79 0.025
cation transport GO:0006812 399 0.025
mitotic cell cycle GO:0000278 195 0.025
nucleobase containing small molecule metabolic process GO:0055086 352 0.025
cellular chemical homeostasis GO:0055082 215 0.025
regulation of system process GO:0044057 200 0.025
positive regulation of cytokine production GO:0001819 174 0.025
Human
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.025
Human
dna metabolic process GO:0006259 303 0.025
positive regulation of protein kinase activity GO:0045860 144 0.025
Human
positive regulation of neuron differentiation GO:0045666 141 0.025
nucleoside phosphate metabolic process GO:0006753 338 0.025
regulation of protein serine threonine kinase activity GO:0071900 157 0.025
leukocyte proliferation GO:0070661 172 0.024
Human
regulation of apoptotic signaling pathway GO:2001233 197 0.024
Human
regulation of leukocyte differentiation GO:1902105 159 0.024
peptidyl tyrosine modification GO:0018212 145 0.024
circulatory system process GO:0003013 197 0.024
adaptive immune response GO:0002250 155 0.024
second messenger mediated signaling GO:0019932 73 0.024
response to organonitrogen compound GO:0010243 246 0.024
negative regulation of peptidase activity GO:0010466 46 0.024
negative regulation of protein processing GO:0010955 79 0.024
polyamine catabolic process GO:0006598 2 0.024
cellular nitrogen compound catabolic process GO:0044270 280 0.024
axonogenesis GO:0007409 274 0.024
intrinsic apoptotic signaling pathway GO:0097193 132 0.024
Human
organic acid biosynthetic process GO:0016053 86 0.024
response to growth factor GO:0070848 198 0.024
cellular ion homeostasis GO:0006873 165 0.024
developmental growth involved in morphogenesis GO:0060560 138 0.024
regulation of cell cycle GO:0051726 281 0.023
regulation of protein tyrosine kinase activity GO:0061097 17 0.023
organic cyclic compound catabolic process GO:1901361 295 0.023
regulation of secretion GO:0051046 274 0.023
response to nutrient levels GO:0031667 109 0.023
peptide metabolic process GO:0006518 46 0.023
regulation of epithelial cell proliferation GO:0050678 141 0.023
blood circulation GO:0008015 195 0.023
regulation of cellular response to stress GO:0080135 159 0.023
Human
membrane organization GO:0061024 245 0.023
Human
negative regulation of protein modification process GO:0031400 163 0.023
adult locomotory behavior GO:0008344 91 0.023
protein catabolic process GO:0030163 221 0.023
Human
negative regulation of defense response GO:0031348 77 0.022
myeloid cell differentiation GO:0030099 233 0.022
cellular response to molecule of bacterial origin GO:0071219 83 0.022
regulation of neuron death GO:1901214 134 0.022
response to molecule of bacterial origin GO:0002237 143 0.022
innate immune response GO:0045087 157 0.022
synapse organization GO:0050808 125 0.022
reactive oxygen species metabolic process GO:0072593 84 0.022
muscle cell differentiation GO:0042692 261 0.022
homeostasis of number of cells GO:0048872 210 0.022
camera type eye development GO:0043010 266 0.022
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.022
regulation of transmembrane transport GO:0034762 128 0.021
epithelial tube morphogenesis GO:0060562 303 0.021
negative regulation of cholesterol transport GO:0032375 4 0.021
regulation of protein catabolic process GO:0042176 108 0.021
Human
fatty acid biosynthetic process GO:0006633 41 0.021
acetate metabolic process GO:0006083 1 0.021
alpha amino acid metabolic process GO:1901605 59 0.021
cellular response to hormone stimulus GO:0032870 150 0.021
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.021
ossification GO:0001503 216 0.021
regulation of calcium mediated signaling GO:0050848 19 0.021
kidney development GO:0001822 213 0.021
g protein coupled receptor signaling pathway GO:0007186 243 0.021
activation of nf kappab inducing kinase activity GO:0007250 4 0.021
transmission of nerve impulse GO:0019226 76 0.021
regulation of protein localization GO:0032880 231 0.021
maintenance of location GO:0051235 89 0.020
regulation of t cell activation GO:0050863 170 0.020
response to light stimulus GO:0009416 135 0.020
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.020
response to copper ion GO:0046688 3 0.020
renal system development GO:0072001 225 0.020
cation transmembrane transport GO:0098655 266 0.020
negative regulation of phosphorylation GO:0042326 166 0.020
ribose phosphate metabolic process GO:0019693 291 0.020
diterpenoid metabolic process GO:0016101 24 0.020
epithelial cell proliferation GO:0050673 174 0.020
nucleotide catabolic process GO:0009166 217 0.020
cellular transition metal ion homeostasis GO:0046916 32 0.020
ion transmembrane transport GO:0034220 361 0.020
stress response to metal ion GO:0097501 3 0.020
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.020
central nervous system neuron differentiation GO:0021953 162 0.020
glycoprotein metabolic process GO:0009100 116 0.019
lung development GO:0030324 164 0.019
heart morphogenesis GO:0003007 178 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.019
transition metal ion homeostasis GO:0055076 54 0.019
positive regulation of cell development GO:0010720 237 0.019
regulation of mitotic cell cycle phase transition GO:1901990 73 0.019
lipid localization GO:0010876 126 0.019
regulation of secretion by cell GO:1903530 249 0.019
positive regulation of cellular catabolic process GO:0031331 148 0.019
Human
cellular metal ion homeostasis GO:0006875 151 0.019
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.019
regulation of lipid metabolic process GO:0019216 118 0.019
zinc ion homeostasis GO:0055069 10 0.019
positive regulation of kinase activity GO:0033674 155 0.019
Human
heterocycle catabolic process GO:0046700 280 0.019
organonitrogen compound catabolic process GO:1901565 264 0.019
endomembrane system organization GO:0010256 147 0.019
Human
lymphocyte proliferation GO:0046651 164 0.018
cellular protein catabolic process GO:0044257 155 0.018
Human
blood vessel morphogenesis GO:0048514 285 0.018
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.018
gliogenesis GO:0042063 141 0.018
Human
response to iron ion GO:0010039 4 0.018
positive regulation of defense response GO:0031349 124 0.018
wnt signaling pathway GO:0016055 188 0.018
monocarboxylic acid biosynthetic process GO:0072330 61 0.018
response to oxygen levels GO:0070482 62 0.018
placenta development GO:0001890 140 0.018
glycosyl compound metabolic process GO:1901657 246 0.018
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.018
inorganic ion transmembrane transport GO:0098660 234 0.018
positive regulation of inflammatory response GO:0050729 47 0.018
positive regulation of lymphocyte activation GO:0051251 140 0.018
regulation of membrane protein ectodomain proteolysis GO:0051043 3 0.018
peptidyl amino acid modification GO:0018193 336 0.018
regulation of transferase activity GO:0051338 263 0.018
Human
learning or memory GO:0007611 148 0.018
axon guidance GO:0007411 141 0.018
nucleoside metabolic process GO:0009116 246 0.018
cellular protein complex assembly GO:0043623 116 0.018
Human
protein secretion GO:0009306 111 0.018
triglyceride metabolic process GO:0006641 51 0.018
neutral lipid metabolic process GO:0006638 57 0.018
regulation of anatomical structure size GO:0090066 178 0.017
lipoprotein metabolic process GO:0042157 43 0.017
negative regulation of response to wounding GO:1903035 77 0.017
lymphocyte differentiation GO:0030098 242 0.017
developmental cell growth GO:0048588 84 0.017
t cell differentiation GO:0030217 174 0.017
translation GO:0006412 93 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.017
acute inflammatory response GO:0002526 41 0.017
regulation of reactive oxygen species metabolic process GO:2000377 40 0.017
response to acid chemical GO:0001101 111 0.017
monosaccharide metabolic process GO:0005996 106 0.017
negative regulation of protein phosphorylation GO:0001933 126 0.017
regulation of neuron apoptotic process GO:0043523 122 0.017
protein modification by small protein conjugation or removal GO:0070647 207 0.017
Human
spermatid development GO:0007286 108 0.017
sulfur compound metabolic process GO:0006790 100 0.017
protein modification by small protein conjugation GO:0032446 187 0.017
Human
interferon gamma production GO:0032609 67 0.017
hexose metabolic process GO:0019318 98 0.017
ras protein signal transduction GO:0007265 77 0.017
metal ion homeostasis GO:0055065 189 0.017
morphogenesis of a branching structure GO:0001763 203 0.017
ribonucleotide metabolic process GO:0009259 291 0.017
regulation of body fluid levels GO:0050878 162 0.017
fertilization GO:0009566 127 0.017
carbohydrate derivative catabolic process GO:1901136 231 0.016
nucleoside monophosphate metabolic process GO:0009123 85 0.016
cellular response to inorganic substance GO:0071241 37 0.016
regulation of interferon gamma production GO:0032649 57 0.016
purine nucleoside triphosphate metabolic process GO:0009144 226 0.016
positive regulation of protein phosphorylation GO:0001934 242 0.016
Human
extrinsic apoptotic signaling pathway GO:0097191 126 0.016
purine ribonucleotide metabolic process GO:0009150 290 0.016
regulation of translation GO:0006417 71 0.016
nucleoside triphosphate catabolic process GO:0009143 205 0.016
divalent inorganic cation homeostasis GO:0072507 138 0.016
regulation of cellular component biogenesis GO:0044087 181 0.016
Human
response to reactive oxygen species GO:0000302 56 0.016
nucleoside catabolic process GO:0009164 206 0.016
response to extracellular stimulus GO:0009991 127 0.016
organ growth GO:0035265 117 0.016
cellular amide metabolic process GO:0043603 58 0.016
regulation of leukocyte proliferation GO:0070663 121 0.016
lymphocyte mediated immunity GO:0002449 139 0.016
cardiac muscle tissue development GO:0048738 130 0.016
positive regulation of secretion by cell GO:1903532 114 0.016
stem cell differentiation GO:0048863 268 0.016
interleukin 8 production GO:0032637 4 0.016
nadph regeneration GO:0006740 2 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
synaptic transmission GO:0007268 329 0.016
organonitrogen compound biosynthetic process GO:1901566 192 0.016
anion transport GO:0006820 177 0.016
respiratory tube development GO:0030323 167 0.016
calcium mediated signaling GO:0019722 46 0.016
immune response regulating signaling pathway GO:0002764 125 0.016
carbohydrate metabolic process GO:0005975 230 0.016
response to metal ion GO:0010038 47 0.016
humoral immune response GO:0006959 57 0.015
positive regulation of cell death GO:0010942 224 0.015
forebrain development GO:0030900 302 0.015
metencephalon development GO:0022037 89 0.015
regulation of cell cycle phase transition GO:1901987 77 0.015
regionalization GO:0003002 337 0.015
ribonucleotide catabolic process GO:0009261 208 0.015
cell maturation GO:0048469 127 0.015
regulation of binding GO:0051098 111 0.015
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.015
angiogenesis GO:0001525 201 0.015
purine ribonucleotide catabolic process GO:0009154 208 0.015
cellular response to organonitrogen compound GO:0071417 145 0.015
cellular macromolecule catabolic process GO:0044265 206 0.015
Human
negative regulation of interleukin 2 production GO:0032703 8 0.015
associative learning GO:0008306 61 0.015
skeletal system development GO:0001501 356 0.015
ribonucleoside triphosphate metabolic process GO:0009199 220 0.015
actin cytoskeleton organization GO:0030036 220 0.015
response to lipopolysaccharide GO:0032496 128 0.015
positive regulation of response to wounding GO:1903036 66 0.015
t cell proliferation GO:0042098 120 0.015
fat soluble vitamin biosynthetic process GO:0042362 4 0.015
purine nucleotide catabolic process GO:0006195 211 0.015
beta amyloid clearance GO:0097242 2 0.015
Human
morphogenesis of a branching epithelium GO:0061138 193 0.015
negative regulation of cell activation GO:0050866 111 0.015
leukocyte migration GO:0050900 124 0.015
aromatic compound catabolic process GO:0019439 286 0.015
negative regulation of cytokine production GO:0001818 84 0.015
positive regulation of cell adhesion GO:0045785 80 0.015
purine nucleoside triphosphate catabolic process GO:0009146 203 0.015
purine ribonucleoside catabolic process GO:0046130 205 0.015
regulation of vesicle mediated transport GO:0060627 139 0.015
cellular response to lipid GO:0071396 145 0.015
modification dependent macromolecule catabolic process GO:0043632 133 0.015
Human
immune response activating signal transduction GO:0002757 116 0.015
ubiquitin dependent protein catabolic process GO:0006511 129 0.015
Human
cellular zinc ion homeostasis GO:0006882 9 0.015
regulation of osteoblast differentiation GO:0045667 67 0.015
nitrogen compound transport GO:0071705 271 0.015
organic anion transport GO:0015711 137 0.015
response to peptide hormone GO:0043434 127 0.015
purine nucleoside metabolic process GO:0042278 241 0.014
cellular response to dna damage stimulus GO:0006974 207 0.014
Human
regulation of mitotic cell cycle GO:0007346 126 0.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.014
regulation of cell growth GO:0001558 91 0.014
regulation of nucleotide metabolic process GO:0006140 169 0.014
epithelial cell development GO:0002064 159 0.014
blood coagulation GO:0007596 76 0.014
engulfment of apoptotic cell GO:0043652 3 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
organophosphate catabolic process GO:0046434 232 0.014
mesenchyme development GO:0060485 152 0.014
fatty acid metabolic process GO:0006631 121 0.014
positive regulation of hydrolase activity GO:0051345 148 0.014
cell activation involved in immune response GO:0002263 126 0.014
glial cell differentiation GO:0010001 131 0.014
Human
activation of membrane attack complex GO:0001905 4 0.014
regulation of ion transmembrane transport GO:0034765 119 0.014
transition metal ion transport GO:0000041 38 0.014
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.014
mitochondrion organization GO:0007005 134 0.014
germ cell development GO:0007281 185 0.014
action potential GO:0001508 78 0.014
glucose metabolic process GO:0006006 92 0.014
hormone metabolic process GO:0042445 86 0.014
rho protein signal transduction GO:0007266 32 0.014
rhythmic process GO:0048511 174 0.014
adult behavior GO:0030534 135 0.014
negative regulation of neuron apoptotic process GO:0043524 92 0.014
peripheral nervous system development GO:0007422 53 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
limb morphogenesis GO:0035108 149 0.014
regulation of multi organism process GO:0043900 111 0.014
regulation of cell adhesion GO:0030155 154 0.014
ribonucleoside monophosphate metabolic process GO:0009161 80 0.014
dendritic spine maintenance GO:0097062 4 0.013
hair follicle development GO:0001942 85 0.013
regulation of ion transport GO:0043269 215 0.013
positive regulation of immune effector process GO:0002699 107 0.013
cellular response to oxidative stress GO:0034599 76 0.013
regulation of eosinophil migration GO:2000416 2 0.013
regulation of endocytosis GO:0030100 69 0.013
regulation of cell cycle process GO:0010564 160 0.013
regulation of epidermal growth factor activated receptor activity GO:0007176 7 0.013
myeloid cell homeostasis GO:0002262 114 0.013
neuromuscular process controlling balance GO:0050885 59 0.013
retinoid metabolic process GO:0001523 24 0.013
single fertilization GO:0007338 82 0.013
heart contraction GO:0060047 93 0.013
nucleoside phosphate catabolic process GO:1901292 222 0.013
tissue remodeling GO:0048771 102 0.013
regulation of cellular component size GO:0032535 121 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
nucleoside triphosphate metabolic process GO:0009141 230 0.013
neuronal action potential GO:0019228 54 0.013
purine containing compound catabolic process GO:0072523 213 0.013
regulation of organelle organization GO:0033043 289 0.013
regulation of protein complex assembly GO:0043254 83 0.013
Human
meiotic nuclear division GO:0007126 115 0.013
endocytosis GO:0006897 168 0.013
ribonucleoside catabolic process GO:0042454 206 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.013
cofactor metabolic process GO:0051186 80 0.013
muscle contraction GO:0006936 101 0.013
regulation of metal ion transport GO:0010959 106 0.013
regulation of receptor activity GO:0010469 41 0.013
regulation of lymphocyte differentiation GO:0045619 107 0.013
cell substrate adhesion GO:0031589 130 0.013
development of primary sexual characteristics GO:0045137 143 0.013
regulation of response to oxidative stress GO:1902882 19 0.013
negative regulation of multi organism process GO:0043901 68 0.013
myelination GO:0042552 74 0.013
Human
positive regulation of proteolysis GO:0045862 85 0.013
Human
negative regulation of lymphocyte activation GO:0051250 91 0.013
mitotic cell cycle process GO:1903047 159 0.013
bone development GO:0060348 120 0.013
hair cycle GO:0042633 90 0.012
telencephalon development GO:0021537 186 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
negative regulation of activated t cell proliferation GO:0046007 7 0.012
cellular response to drug GO:0035690 15 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
regulation of lymphocyte proliferation GO:0050670 117 0.012
positive regulation of cell motility GO:2000147 116 0.012
midgut development GO:0007494 4 0.012
glycerophospholipid metabolic process GO:0006650 71 0.012
terpenoid metabolic process GO:0006721 25 0.012
regulation of protein binding GO:0043393 60 0.012
cellular response to biotic stimulus GO:0071216 92 0.012
isoprenoid metabolic process GO:0006720 29 0.012
negative regulation of transferase activity GO:0051348 85 0.012
positive regulation of secretion GO:0051047 130 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
regulation of t cell proliferation GO:0042129 92 0.012
regulation of nucleotide catabolic process GO:0030811 122 0.012
sensory system development GO:0048880 3 0.012
regulation of cholesterol metabolic process GO:0090181 14 0.012
positive regulation of protein transport GO:0051222 93 0.012
canonical wnt signaling pathway GO:0060070 130 0.012
negative regulation of mapk cascade GO:0043409 65 0.012

Clu disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.255
nervous system disease DOID:863 0 0.255
central nervous system disease DOID:331 0 0.143
disease of metabolism DOID:0014667 0 0.106
inherited metabolic disorder DOID:655 0 0.106
retinal disease DOID:5679 0 0.040
sensory system disease DOID:0050155 0 0.040
eye and adnexa disease DOID:1492 0 0.040
eye disease DOID:5614 0 0.040
brain disease DOID:936 0 0.038
retinal degeneration DOID:8466 0 0.035
immune system disease DOID:2914 0 0.032
hematopoietic system disease DOID:74 0 0.030
acquired metabolic disease DOID:0060158 0 0.029
neurodegenerative disease DOID:1289 0 0.018
cardiovascular system disease DOID:1287 0 0.016
anemia DOID:2355 0 0.013
musculoskeletal system disease DOID:17 0 0.013
bone disease DOID:0080001 0 0.012
connective tissue disease DOID:65 0 0.012