Mus musculus

112 known processes

Spred1

sprouty protein with EVH-1 domain 1, related sequence

(Aliases: AW047647,5730461F13Rik,AL024345)

Spred1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of protein kinase activity GO:0045859 232 0.501
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902043 13 0.359
morphogenesis of a branching epithelium GO:0061138 193 0.317
fat cell differentiation GO:0045444 160 0.301
embryonic epithelial tube formation GO:0001838 130 0.256
Mouse
purine ribonucleoside metabolic process GO:0046128 241 0.240
cellular amino acid metabolic process GO:0006520 103 0.239
regulation of cellular ketone metabolic process GO:0010565 66 0.238
glycosyl compound metabolic process GO:1901657 246 0.235
epithelial tube morphogenesis GO:0060562 303 0.233
Mouse
amine metabolic process GO:0009308 45 0.230
blood vessel morphogenesis GO:0048514 285 0.210
Zebrafish
regulation of mapk cascade GO:0043408 248 0.193
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.185
regulation of cellular amino acid metabolic process GO:0006521 5 0.183
ras protein signal transduction GO:0007265 77 0.181
axonogenesis GO:0007409 274 0.173
Mouse
negative regulation of cellular amine metabolic process GO:0033239 1 0.173
t cell activation GO:0042110 289 0.169
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.168
cellular nitrogen compound catabolic process GO:0044270 280 0.166
lipid biosynthetic process GO:0008610 179 0.164
regulation of kinase activity GO:0043549 249 0.162
regulation of cellular catabolic process GO:0031329 242 0.155
inflammatory response GO:0006954 244 0.150
negative regulation of molecular function GO:0044092 258 0.145
purine nucleoside metabolic process GO:0042278 241 0.141
cellular amine metabolic process GO:0044106 44 0.140
response to organonitrogen compound GO:0010243 246 0.140
regulation of cell migration GO:0030334 219 0.139
regulation of organelle organization GO:0033043 289 0.133
Mouse
negative regulation of synapse assembly GO:0051964 3 0.133
regulation of cellular amine metabolic process GO:0033238 20 0.131
wnt signaling pathway GO:0016055 188 0.131
regulation of t cell activation GO:0050863 170 0.128
regulation of neuron differentiation GO:0045664 281 0.128
t cell differentiation GO:0030217 174 0.125
positive regulation of cellular catabolic process GO:0031331 148 0.124
regulation of purine nucleotide metabolic process GO:1900542 169 0.123
cellular macromolecule catabolic process GO:0044265 206 0.123
branching morphogenesis of an epithelial tube GO:0048754 159 0.122
regulation of lymphocyte activation GO:0051249 240 0.121
morphogenesis of a branching structure GO:0001763 203 0.121
regionalization GO:0003002 337 0.118
negative regulation of protein phosphorylation GO:0001933 126 0.118
transmembrane transport GO:0055085 412 0.118
primary neural tube formation GO:0014020 95 0.118
Mouse
glycosyl compound catabolic process GO:1901658 206 0.118
regulation of cell cycle GO:0051726 281 0.114
ribonucleoside triphosphate metabolic process GO:0009199 220 0.113
cation transport GO:0006812 399 0.112
positive regulation of protein modification process GO:0031401 299 0.112
small gtpase mediated signal transduction GO:0007264 97 0.109
establishment of organelle localization GO:0051656 122 0.109
regulation of response to wounding GO:1903034 189 0.105
lymphocyte differentiation GO:0030098 242 0.103
nucleoside phosphate metabolic process GO:0006753 338 0.102
gland development GO:0048732 330 0.100
positive regulation of protein phosphorylation GO:0001934 242 0.098
myelination in peripheral nervous system GO:0022011 19 0.097
cell fate commitment GO:0045165 210 0.097
cellular response to hormone stimulus GO:0032870 150 0.096
ubiquitin dependent protein catabolic process GO:0006511 129 0.096
extrinsic apoptotic signaling pathway GO:0097191 126 0.093
nucleotide metabolic process GO:0009117 332 0.093
regulation of cell activation GO:0050865 289 0.092
positive regulation of leukocyte differentiation GO:1902107 86 0.091
placenta development GO:0001890 140 0.091
circadian rhythm GO:0007623 114 0.091
response to insulin GO:0032868 100 0.091
regulation of leukocyte differentiation GO:1902105 159 0.089
regulation of inflammatory response GO:0050727 147 0.089
alpha beta t cell activation GO:0046631 91 0.088
aromatic compound catabolic process GO:0019439 286 0.088
nucleoside metabolic process GO:0009116 246 0.087
positive regulation of cell death GO:0010942 224 0.087
neural tube development GO:0021915 160 0.086
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.086
developmental maturation GO:0021700 193 0.086
cellular response to insulin stimulus GO:0032869 78 0.086
regulation of nucleoside metabolic process GO:0009118 130 0.086
regulation of ion transport GO:0043269 215 0.086
response to peptide hormone GO:0043434 127 0.084
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.082
Zebrafish
rhythmic process GO:0048511 174 0.082
development of primary sexual characteristics GO:0045137 143 0.082
gtp catabolic process GO:0006184 143 0.081
negative regulation of immune system process GO:0002683 209 0.081
action potential GO:0001508 78 0.079
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.079
glial cell differentiation GO:0010001 131 0.079
adaptive immune response GO:0002250 155 0.079
organophosphate catabolic process GO:0046434 232 0.079
negative regulation of defense response GO:0031348 77 0.078
guanosine containing compound metabolic process GO:1901068 144 0.077
regulation of apoptotic signaling pathway GO:2001233 197 0.076
epithelial tube formation GO:0072175 130 0.076
Mouse
positive regulation of alpha beta t cell differentiation GO:0046638 28 0.076
nitrogen compound transport GO:0071705 271 0.076
positive regulation of apoptotic process GO:0043065 217 0.076
regulation of cellular component size GO:0032535 121 0.076
Mouse
positive regulation of lymphocyte activation GO:0051251 140 0.076
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.075
negative regulation of cell proliferation GO:0008285 296 0.075
regulation of transferase activity GO:0051338 263 0.075
neural tube closure GO:0001843 90 0.075
Mouse
regulation of membrane potential GO:0042391 192 0.075
leukocyte differentiation GO:0002521 342 0.074
heterocycle catabolic process GO:0046700 280 0.074
stem cell differentiation GO:0048863 268 0.074
ribonucleoside metabolic process GO:0009119 245 0.074
regulation of intracellular protein transport GO:0033157 82 0.074
purine nucleotide metabolic process GO:0006163 302 0.073
positive regulation of cellular protein catabolic process GO:1903364 34 0.072
epidermis development GO:0008544 187 0.072
positive regulation of cell development GO:0010720 237 0.071
cellular ketone metabolic process GO:0042180 84 0.071
purine nucleotide catabolic process GO:0006195 211 0.071
regulation of activation of jak2 kinase activity GO:0010534 1 0.070
guanosine containing compound catabolic process GO:1901069 144 0.069
insulin receptor signaling pathway GO:0008286 49 0.068
negative regulation of protein modification process GO:0031400 163 0.068
peptidyl tyrosine phosphorylation GO:0018108 143 0.068
positive regulation of t cell activation GO:0050870 101 0.067
cellular protein catabolic process GO:0044257 155 0.067
purine nucleoside triphosphate metabolic process GO:0009144 226 0.066
actin cytoskeleton organization GO:0030036 220 0.066
Mouse
gliogenesis GO:0042063 141 0.066
ribose phosphate metabolic process GO:0019693 291 0.066
purine nucleoside triphosphate catabolic process GO:0009146 203 0.065
forebrain development GO:0030900 302 0.065
ion transmembrane transport GO:0034220 361 0.065
axon guidance GO:0007411 141 0.065
Mouse
jak stat cascade GO:0007259 42 0.065
nucleoside triphosphate metabolic process GO:0009141 230 0.065
modification dependent macromolecule catabolic process GO:0043632 133 0.065
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.065
regulation of defense response GO:0031347 233 0.064
response to growth factor GO:0070848 198 0.064
Zebrafish
regulation of cell projection organization GO:0031344 206 0.063
connective tissue development GO:0061448 179 0.063
nucleoside catabolic process GO:0009164 206 0.062
digestive tract development GO:0048565 190 0.062
positive regulation of lymphocyte differentiation GO:0045621 61 0.062
regulation of cell motility GO:2000145 236 0.061
regulation of insulin receptor signaling pathway GO:0046626 21 0.061
ensheathment of neurons GO:0007272 76 0.061
ribonucleotide metabolic process GO:0009259 291 0.061
mapk cascade GO:0000165 281 0.060
endocytosis GO:0006897 168 0.060
positive regulation of kinase activity GO:0033674 155 0.060
positive regulation of protein kinase activity GO:0045860 144 0.059
neuronal action potential GO:0019228 54 0.058
rac protein signal transduction GO:0016601 13 0.058
cellular response to organonitrogen compound GO:0071417 145 0.058
regulation of lymphocyte differentiation GO:0045619 107 0.058
developmental growth involved in morphogenesis GO:0060560 138 0.058
proteasomal protein catabolic process GO:0010498 98 0.058
negative regulation of lymphocyte activation GO:0051250 91 0.057
positive regulation of t cell differentiation GO:0045582 52 0.057
multicellular organismal signaling GO:0035637 91 0.056
peptidyl amino acid modification GO:0018193 336 0.056
negative regulation of tyrosine phosphorylation of stat protein GO:0042532 3 0.056
actin filament organization GO:0007015 113 0.056
Mouse
positive regulation of proteolysis GO:0045862 85 0.056
leukocyte migration GO:0050900 124 0.056
cell adhesion GO:0007155 329 0.056
dephosphorylation GO:0016311 129 0.056
Human
negative regulation of inflammatory response GO:0050728 61 0.055
regulation of t cell differentiation GO:0045580 83 0.055
cellular lipid metabolic process GO:0044255 323 0.055
positive regulation of cell activation GO:0050867 158 0.055
organonitrogen compound catabolic process GO:1901565 264 0.054
negative regulation of phosphate metabolic process GO:0045936 184 0.054
regulation of alpha beta t cell activation GO:0046634 53 0.053
oocyte construction GO:0007308 2 0.053
peptide transport GO:0015833 133 0.053
axon ensheathment GO:0008366 76 0.052
peptidyl threonine modification GO:0018210 31 0.052
purine containing compound catabolic process GO:0072523 213 0.052
negative regulation of intracellular signal transduction GO:1902532 167 0.052
negative regulation of t helper 2 cell differentiation GO:0045629 4 0.051
negative regulation of cellular protein metabolic process GO:0032269 247 0.051
negative regulation of response to wounding GO:1903035 77 0.050
positive regulation of transferase activity GO:0051347 167 0.050
regulation of nucleotide metabolic process GO:0006140 169 0.050
negative regulation of epidermal growth factor activated receptor activity GO:0007175 3 0.050
ribonucleoside triphosphate catabolic process GO:0009203 199 0.050
oocyte axis specification GO:0007309 2 0.050
myelination GO:0042552 74 0.050
immune effector process GO:0002252 321 0.049
tube formation GO:0035148 140 0.049
Mouse
amide transport GO:0042886 138 0.049
positive regulation of neuron differentiation GO:0045666 141 0.049
organic cyclic compound catabolic process GO:1901361 295 0.048
response to lipopolysaccharide GO:0032496 128 0.048
cytoplasmic transport GO:0016482 234 0.047
negative regulation of phosphorylation GO:0042326 166 0.047
response to peptide GO:1901652 136 0.047
neural tube formation GO:0001841 108 0.047
Mouse
regulation of secretion by cell GO:1903530 249 0.047
regulation of wnt signaling pathway GO:0030111 123 0.046
regulation of neuron apoptotic process GO:0043523 122 0.046
regulation of actin polymerization or depolymerization GO:0008064 45 0.046
Mouse
carboxylic acid biosynthetic process GO:0046394 86 0.046
fatty acid metabolic process GO:0006631 121 0.046
cellular response to peptide GO:1901653 92 0.046
respiratory tube development GO:0030323 167 0.045
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.045
monocarboxylic acid metabolic process GO:0032787 191 0.045
multicellular organism growth GO:0035264 161 0.045
regulation of gtp catabolic process GO:0033124 113 0.045
inorganic ion transmembrane transport GO:0098660 234 0.045
germ cell development GO:0007281 185 0.045
negative regulation of growth GO:0045926 99 0.045
positive regulation of hydrolase activity GO:0051345 148 0.045
single organism cell adhesion GO:0098602 156 0.044
regulation of system process GO:0044057 200 0.044
small molecule biosynthetic process GO:0044283 132 0.044
spongiotrophoblast layer development GO:0060712 15 0.044
purine nucleoside catabolic process GO:0006152 205 0.044
cellular response to cytokine stimulus GO:0071345 189 0.044
cellular response to peptide hormone stimulus GO:0071375 92 0.044
nucleoside phosphate catabolic process GO:1901292 222 0.044
regulation of ras protein signal transduction GO:0046578 114 0.044
regulation of protein transport GO:0051223 163 0.043
mesonephric tubule development GO:0072164 94 0.043
regulation of establishment of protein localization GO:0070201 181 0.043
fertilization GO:0009566 127 0.043
regulation of map kinase activity GO:0043405 120 0.043
cation transmembrane transport GO:0098655 266 0.042
purine ribonucleotide metabolic process GO:0009150 290 0.042
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.042
regulation of chemotaxis GO:0050920 53 0.042
protein ubiquitination GO:0016567 171 0.042
apoptotic signaling pathway GO:0097190 306 0.042
locomotory behavior GO:0007626 195 0.041
regulation of proteasomal protein catabolic process GO:0061136 46 0.041
sensory perception GO:0007600 245 0.041
skeletal system morphogenesis GO:0048705 203 0.041
g protein coupled receptor signaling pathway GO:0007186 243 0.041
positive regulation of t helper 1 cell differentiation GO:0045627 4 0.041
sensory organ morphogenesis GO:0090596 242 0.041
gastrulation GO:0007369 116 0.041
protein kinase b signaling GO:0043491 74 0.040
organ growth GO:0035265 117 0.040
regulation of ras gtpase activity GO:0032318 88 0.040
regulation of cell adhesion GO:0030155 154 0.040
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.040
positive regulation of apoptotic signaling pathway GO:2001235 95 0.040
skeletal system development GO:0001501 356 0.040
negative regulation of ras protein signal transduction GO:0046580 18 0.040
smoothened signaling pathway GO:0007224 105 0.040
regulation of cytokine production GO:0001817 266 0.039
cellular divalent inorganic cation homeostasis GO:0072503 127 0.039
epithelial cell development GO:0002064 159 0.039
cell type specific apoptotic process GO:0097285 268 0.039
ureteric bud development GO:0001657 94 0.039
nucleotide catabolic process GO:0009166 217 0.039
muscle cell differentiation GO:0042692 261 0.039
regulation of alpha beta t cell differentiation GO:0046637 35 0.039
negative regulation of cell activation GO:0050866 111 0.039
regulation of circadian rhythm GO:0042752 58 0.039
ossification GO:0001503 216 0.038
learning GO:0007612 98 0.038
positive regulation of cellular amine metabolic process GO:0033240 5 0.038
mesoderm development GO:0007498 100 0.038
purine containing compound metabolic process GO:0072521 311 0.038
ribonucleotide catabolic process GO:0009261 208 0.038
intracellular protein transport GO:0006886 204 0.037
regulation of protein localization GO:0032880 231 0.037
synaptic transmission GO:0007268 329 0.037
purine ribonucleoside catabolic process GO:0046130 205 0.037
positive regulation of ras gtpase activity GO:0032320 65 0.037
regulation of adaptive immune response GO:0002819 90 0.037
synapse organization GO:0050808 125 0.036
regulation of secretion GO:0051046 274 0.036
telencephalon development GO:0021537 186 0.036
wound healing GO:0042060 157 0.036
negative regulation of nervous system development GO:0051961 156 0.036
protein modification by small protein conjugation or removal GO:0070647 207 0.036
spermatogenesis GO:0007283 284 0.036
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.035
regulation of vesicle mediated transport GO:0060627 139 0.035
single organismal cell cell adhesion GO:0016337 131 0.035
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.035
microtubule based process GO:0007017 236 0.035
apical constriction GO:0003383 4 0.035
negative regulation of cellular component organization GO:0051129 194 0.035
positive regulation of mapk cascade GO:0043410 170 0.034
regulation of hormone levels GO:0010817 211 0.034
regulation of intracellular transport GO:0032386 159 0.034
mesenchyme development GO:0060485 152 0.034
actin filament polymerization GO:0030041 44 0.034
Mouse
cognition GO:0050890 149 0.034
regulation of organ morphogenesis GO:2000027 144 0.034
retina development in camera type eye GO:0060041 119 0.033
protein polymerization GO:0051258 57 0.033
Mouse
regulation of vasculature development GO:1901342 88 0.033
regulation of neuron projection development GO:0010975 169 0.033
positive regulation of nervous system development GO:0051962 221 0.033
bone development GO:0060348 120 0.033
epithelium migration GO:0090132 63 0.032
glucose transport GO:0015758 56 0.032
response to extracellular stimulus GO:0009991 127 0.032
modification dependent protein catabolic process GO:0019941 133 0.032
peptidyl tyrosine modification GO:0018212 145 0.032
photoreceptor cell differentiation GO:0046530 52 0.032
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.032
inorganic cation transmembrane transport GO:0098662 207 0.032
organic acid biosynthetic process GO:0016053 86 0.032
negative regulation of organelle organization GO:0010639 90 0.032
exocytosis GO:0006887 121 0.032
epithelial cell migration GO:0010631 63 0.032
regulation of blood circulation GO:1903522 93 0.032
cell growth GO:0016049 130 0.031
gtp metabolic process GO:0046039 144 0.031
photoreceptor cell development GO:0042461 40 0.031
male gamete generation GO:0048232 285 0.031
morphogenesis of embryonic epithelium GO:0016331 159 0.031
Mouse
negative regulation of insulin receptor signaling pathway GO:0046627 14 0.031
cellular calcium ion homeostasis GO:0006874 119 0.030
mesoderm formation GO:0001707 62 0.030
establishment or maintenance of cell polarity GO:0007163 86 0.030
negative regulation of protein metabolic process GO:0051248 282 0.030
chondrocyte development GO:0002063 24 0.030
maintenance of location GO:0051235 89 0.030
glycoprotein metabolic process GO:0009100 116 0.029
carbohydrate homeostasis GO:0033500 128 0.029
nucleocytoplasmic transport GO:0006913 139 0.029
glial cell development GO:0021782 54 0.029
mitotic cell cycle process GO:1903047 159 0.029
negative regulation of map kinase activity GO:0043407 34 0.029
establishment of protein localization to organelle GO:0072594 118 0.029
protein maturation GO:0051604 176 0.029
positive regulation of programmed cell death GO:0043068 218 0.029
mesodermal cell migration GO:0008078 4 0.029
regulation of embryonic development GO:0045995 71 0.029
fatty acid biosynthetic process GO:0006633 41 0.029
regulation of pigment cell differentiation GO:0050932 7 0.028
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.028
regulation of cytoskeleton organization GO:0051493 122 0.028
Mouse
rho protein signal transduction GO:0007266 32 0.028
cell chemotaxis GO:0060326 81 0.028
response to alcohol GO:0097305 48 0.028
kidney development GO:0001822 213 0.028
peripheral nervous system development GO:0007422 53 0.028
cellular ion homeostasis GO:0006873 165 0.028
schwann cell differentiation GO:0014037 26 0.028
layer formation in cerebral cortex GO:0021819 13 0.028
protein catabolic process GO:0030163 221 0.028
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 17 0.027
regulation of protein tyrosine kinase activity GO:0061097 17 0.027
spermatid differentiation GO:0048515 115 0.027
response to organic cyclic compound GO:0014070 198 0.027
positive regulation of organelle organization GO:0010638 128 0.027
Mouse
positive regulation of alpha beta t cell activation GO:0046635 39 0.027
negative regulation of t cell activation GO:0050868 65 0.027
lipid localization GO:0010876 126 0.027
forebrain cell migration GO:0021885 58 0.027
adult behavior GO:0030534 135 0.027
interleukin 13 secretion GO:0072611 2 0.027
monocarboxylic acid biosynthetic process GO:0072330 61 0.027
metal ion homeostasis GO:0055065 189 0.027
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.027
cellular homeostasis GO:0019725 240 0.027
schwann cell development GO:0014044 22 0.027
digestive system development GO:0055123 200 0.027
regulation of protein catabolic process GO:0042176 108 0.027
hindbrain development GO:0030902 128 0.027
heart morphogenesis GO:0003007 178 0.027
response to radiation GO:0009314 165 0.027
gonad morphogenesis GO:0035262 1 0.027
cell division GO:0051301 120 0.027
cell fate specification GO:0001708 72 0.026
chemotaxis GO:0006935 247 0.026
Mouse
mammary gland morphogenesis GO:0060443 54 0.026
immune response regulating signaling pathway GO:0002764 125 0.026
macromolecule catabolic process GO:0009057 281 0.026
cell differentiation involved in embryonic placenta development GO:0060706 26 0.026
activation of janus kinase activity GO:0042976 2 0.026
insulin secretion GO:0030073 89 0.026
lateral inhibition GO:0046331 1 0.026
cellular carbohydrate metabolic process GO:0044262 119 0.026
nucleoside triphosphate catabolic process GO:0009143 205 0.026
gonad development GO:0008406 141 0.026
divalent inorganic cation transport GO:0072511 178 0.026
lung development GO:0030324 164 0.026
carbohydrate derivative catabolic process GO:1901136 231 0.026
divalent metal ion transport GO:0070838 172 0.026
regulation of activation of janus kinase activity GO:0010533 1 0.026
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.026
organelle localization GO:0051640 179 0.026
oxidation reduction process GO:0055114 342 0.025
regulation of cd4 positive alpha beta t cell activation GO:2000514 24 0.025
positive regulation of cell motility GO:2000147 116 0.025
regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity GO:0031585 2 0.025
negative regulation of tyrosine phosphorylation of stat3 protein GO:0042518 1 0.025
cartilage development GO:0051216 140 0.025
cell maturation GO:0048469 127 0.025
regulation of cellular response to growth factor stimulus GO:0090287 82 0.025
Zebrafish
regulation of cellular component biogenesis GO:0044087 181 0.025
Mouse
protein processing GO:0016485 163 0.025
regulation of cellular response to stress GO:0080135 159 0.025
cell activation involved in immune response GO:0002263 126 0.025
alpha beta t cell differentiation GO:0046632 69 0.025
membrane organization GO:0061024 245 0.025
peptide secretion GO:0002790 114 0.025
regulation of anatomical structure size GO:0090066 178 0.025
Mouse
camera type eye development GO:0043010 266 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.024
radial glia guided migration of purkinje cell GO:0021942 6 0.024
regulation of erk1 and erk2 cascade GO:0070372 71 0.024
cellular response to dna damage stimulus GO:0006974 207 0.024
regulation of nucleocytoplasmic transport GO:0046822 73 0.024
organelle fission GO:0048285 170 0.024
placenta blood vessel development GO:0060674 31 0.024
positive regulation of nucleotide catabolic process GO:0030813 88 0.024
lymphocyte mediated immunity GO:0002449 139 0.024
mesonephric epithelium development GO:0072163 94 0.024
spermatid development GO:0007286 108 0.024
cellular response to lipid GO:0071396 145 0.024
rap protein signal transduction GO:0032486 3 0.024
respiratory system development GO:0060541 190 0.023
stress activated protein kinase signaling cascade GO:0031098 81 0.023
myeloid cell differentiation GO:0030099 233 0.023
ribonucleoside catabolic process GO:0042454 206 0.023
protein glycosylation GO:0006486 55 0.023
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.023
negative regulation of cellular response to insulin stimulus GO:1900077 16 0.023
positive regulation of protein transport GO:0051222 93 0.023
negative regulation of neuron apoptotic process GO:0043524 92 0.023
response to acid chemical GO:0001101 111 0.023
response to oxidative stress GO:0006979 123 0.023
positive regulation of neuron projection development GO:0010976 79 0.023
midgut development GO:0007494 4 0.023
regulation of purine nucleotide catabolic process GO:0033121 122 0.023
regulation of cell projection assembly GO:0060491 38 0.023
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.023
chondrocyte differentiation GO:0002062 72 0.023
skin development GO:0043588 220 0.022
regulation of nucleotide catabolic process GO:0030811 122 0.022
axis elongation GO:0003401 30 0.022
regulation of cellular protein catabolic process GO:1903362 61 0.022
intracellular mrna localization GO:0008298 4 0.022
regulation of transmembrane transport GO:0034762 128 0.022
regulation of proteolysis GO:0030162 164 0.022
cellular metal ion homeostasis GO:0006875 151 0.022
glucose homeostasis GO:0042593 128 0.022
cellular response to amino acid stimulus GO:0071230 29 0.022
blastocyst development GO:0001824 80 0.022
positive regulation of immune effector process GO:0002699 107 0.022
negative regulation of cell migration GO:0030336 59 0.022
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.022
ear development GO:0043583 200 0.022
angiogenesis GO:0001525 201 0.022
cellular response to growth factor stimulus GO:0071363 197 0.021
Zebrafish
hormone secretion GO:0046879 128 0.021
monosaccharide transport GO:0015749 58 0.021
response to molecule of bacterial origin GO:0002237 143 0.021
defense response to other organism GO:0098542 197 0.021
female gamete generation GO:0007292 74 0.021
positive regulation of ubiquitin protein transferase activity GO:0051443 4 0.021
cellular response to abiotic stimulus GO:0071214 56 0.021
negative regulation of neuron death GO:1901215 98 0.021
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.021
peptidyl serine phosphorylation GO:0018105 74 0.021
positive regulation of endocytosis GO:0045807 42 0.021
regulation of cell shape GO:0008360 39 0.021
protein modification by small protein conjugation GO:0032446 187 0.021
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.020
production of molecular mediator of immune response GO:0002440 103 0.020
cation homeostasis GO:0055080 212 0.020
cd4 positive alpha beta t cell activation GO:0035710 45 0.020
bmp signaling pathway GO:0030509 93 0.020
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.020
regulation of fat cell differentiation GO:0045598 81 0.020
epithelial cell proliferation GO:0050673 174 0.020
organonitrogen compound biosynthetic process GO:1901566 192 0.020
regulation of protein complex assembly GO:0043254 83 0.020
Mouse
peptide hormone secretion GO:0030072 109 0.020
positive regulation of jnk cascade GO:0046330 46 0.020
purine ribonucleotide catabolic process GO:0009154 208 0.020
chondrocyte hypertrophy GO:0003415 4 0.020

Spred1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.135
disease of cellular proliferation DOID:14566 0 0.135
organ system cancer DOID:0050686 0 0.135
colon carcinoma DOID:1520 0 0.029
large intestine cancer DOID:5672 0 0.029
colon cancer DOID:219 0 0.029
gastrointestinal system cancer DOID:3119 0 0.029
intestinal cancer DOID:10155 0 0.029
colorectal cancer DOID:9256 0 0.029
non syndromic intellectual disability DOID:0050889 0 0.028
disease of mental health DOID:150 0 0.028
developmental disorder of mental health DOID:0060037 0 0.028
specific developmental disorder DOID:0060038 0 0.028
intellectual disability DOID:1059 0 0.028