Mus musculus

4 known processes

Tap1

transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)

(Aliases: ABC17,TAP,Ham1,Ham-1,RING4,MTP1,Abcb2,APT1,PSF1,Y3,Tap-1)

Tap1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of t cell mediated cytotoxicity GO:0001916 15 1.000
Mouse
antigen processing and presentation of peptide antigen via mhc class i GO:0002474 9 1.000
Human Mouse
negative regulation of natural killer cell mediated immunity GO:0002716 5 0.999
Rat
antigen processing and presentation of endogenous peptide antigen via mhc class i GO:0019885 3 0.998
Human Mouse
regulation of t cell mediated cytotoxicity GO:0001914 18 0.998
Mouse
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.995
Mouse Rat
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.983
Mouse
antigen processing and presentation of endogenous peptide antigen via mhc class ib GO:0002476 4 0.958
Mouse
regulation of natural killer cell mediated immunity GO:0002715 19 0.941
Rat
antigen processing and presentation of exogenous antigen GO:0019884 26 0.883
Mouse
antigen processing and presentation of exogenous peptide antigen via mhc class ib GO:0002477 3 0.867
Mouse
lymphocyte mediated immunity GO:0002449 139 0.837
Mouse Rat
antigen processing and presentation of exogenous peptide antigen GO:0002478 21 0.826
Mouse
positive regulation of adaptive immune response GO:0002821 61 0.824
Mouse
antigen processing and presentation of peptide antigen via mhc class ib GO:0002428 5 0.816
Mouse
iron ion import GO:0097286 5 0.784
antigen processing and presentation of endogenous peptide antigen GO:0002483 6 0.762
Human Mouse
iron ion import into cell GO:0097459 4 0.712
striated muscle myosin thick filament assembly GO:0071688 1 0.670
Worm
regulation of leukocyte mediated immunity GO:0002703 104 0.669
Mouse Rat
myosin filament organization GO:0031033 3 0.613
Worm
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway tap dependent GO:0002485 3 0.598
Mouse
rna interference GO:0016246 2 0.596
Worm
negative regulation of immune system process GO:0002683 209 0.581
Rat
negative regulation of defense response GO:0031348 77 0.580
Rat
antigen processing and presentation of peptide antigen GO:0048002 29 0.573
Human Mouse
regulation of lymphocyte mediated immunity GO:0002706 84 0.570
Mouse Rat
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway GO:0002484 3 0.568
Mouse
adaptive immune response GO:0002250 155 0.566
Mouse
positive regulation of t cell mediated immunity GO:0002711 24 0.533
Mouse
innate immune response GO:0045087 157 0.510
Rat
intracellular transport of virus GO:0075733 1 0.507
Human
cellular component assembly involved in morphogenesis GO:0010927 139 0.490
Worm
antigen processing and presentation via mhc class ib GO:0002475 8 0.480
Mouse
antigen processing and presentation GO:0019882 47 0.446
Human Mouse
regulation of defense response GO:0031347 233 0.445
Rat
regulation of t cell mediated immunity GO:0002709 34 0.429
Mouse
leukocyte mediated cytotoxicity GO:0001909 62 0.408
Mouse Rat
positive regulation of cell killing GO:0031343 33 0.406
Mouse
natural killer cell mediated cytotoxicity GO:0042267 29 0.401
Rat
posttranscriptional gene silencing by rna GO:0035194 10 0.401
Worm
response to molecule of bacterial origin GO:0002237 143 0.382
Mouse
natural killer cell mediated immunity GO:0002228 29 0.364
Rat
posttranscriptional regulation of gene expression GO:0010608 155 0.364
Worm
t cell mediated immunity GO:0002456 50 0.364
Mouse
positive regulation of defense response GO:0031349 124 0.363
interspecies interaction between organisms GO:0044419 83 0.354
Human
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.353
Mouse
regulation of natural killer cell mediated cytotoxicity GO:0042269 19 0.316
Rat
cation transport GO:0006812 399 0.298
antigen processing and presentation of endogenous peptide antigen via mhc class ib via er pathway GO:0002488 2 0.297
Mouse
myosin filament assembly GO:0031034 2 0.270
Worm
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.252
Mouse
positive regulation of leukocyte mediated immunity GO:0002705 70 0.249
Mouse
negative regulation of leukocyte mediated immunity GO:0002704 29 0.248
Rat
organelle assembly GO:0070925 177 0.244
Worm
regulation of adaptive immune response GO:0002819 90 0.242
Mouse
positive regulation of innate immune response GO:0045089 80 0.238
response to cadmium ion GO:0046686 8 0.238
muscle cell development GO:0055001 133 0.208
Worm
antigen processing and presentation of endogenous antigen GO:0019883 6 0.199
Human Mouse
lysosomal transport GO:0007041 10 0.185
Worm
apoptotic signaling pathway GO:0097190 306 0.180
response to inorganic substance GO:0010035 96 0.178
t cell mediated cytotoxicity GO:0001913 26 0.177
Mouse
cytoplasmic transport GO:0016482 234 0.174
Human
actomyosin structure organization GO:0031032 56 0.173
Worm
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.172
leukocyte mediated immunity GO:0002443 174 0.169
Mouse Rat
t cell proliferation GO:0042098 120 0.163
viral life cycle GO:0019058 36 0.163
Human
production of molecular mediator of immune response GO:0002440 103 0.162
negative regulation of innate immune response GO:0045824 17 0.158
Rat
iron ion homeostasis GO:0055072 36 0.144
fat cell differentiation GO:0045444 160 0.137
antigen processing and presentation of exogenous protein antigen via mhc class ib tap dependent GO:0002481 3 0.135
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.134
Rat
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.124
Mouse
defense response to bacterium GO:0042742 119 0.123
regulation of cell killing GO:0031341 40 0.123
Mouse Rat
antigen processing and presentation of exogenous peptide antigen via mhc class i GO:0042590 6 0.121
positive regulation of antigen processing and presentation GO:0002579 10 0.118
lymphocyte activation involved in immune response GO:0002285 93 0.112
reactive oxygen species biosynthetic process GO:1903409 8 0.109
antigen processing and presentation of endogenous peptide antigen via mhc class ib via er pathway tap dependent GO:0002489 2 0.109
Mouse
regulation of interferon gamma production GO:0032649 57 0.103
negative regulation of lymphocyte mediated immunity GO:0002707 21 0.097
Rat
epithelial cell proliferation GO:0050673 174 0.095
regulation of lymphocyte activation GO:0051249 240 0.091
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.091
regulation of cd8 positive alpha beta t cell activation GO:2001185 3 0.084
regulation of myd88 independent toll like receptor signaling pathway GO:0034127 1 0.082
response to lipopolysaccharide GO:0032496 128 0.081
alpha beta t cell activation GO:0046631 91 0.081
muscle cell differentiation GO:0042692 261 0.081
Worm
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.081
Rat
purine ribonucleoside metabolic process GO:0046128 241 0.080
Rat
regulation of innate immune response GO:0045088 91 0.080
Rat
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.078
regulation of reactive oxygen species metabolic process GO:2000377 40 0.076
myofibril assembly GO:0030239 34 0.075
Worm
cellular response to interferon gamma GO:0071346 25 0.073
reactive oxygen species metabolic process GO:0072593 84 0.072
regulation of alpha beta t cell proliferation GO:0046640 18 0.070
response to metal ion GO:0010038 47 0.069
positive regulation of response to cytokine stimulus GO:0060760 11 0.069
immune effector process GO:0002252 321 0.067
Mouse Rat
purine containing compound catabolic process GO:0072523 213 0.065
Rat
cellular amino acid metabolic process GO:0006520 103 0.063
t cell activation GO:0042110 289 0.061
positive regulation of cellular amine metabolic process GO:0033240 5 0.060
striated muscle cell development GO:0055002 125 0.059
Worm
interaction with host GO:0051701 22 0.058
Human
peptide transport GO:0015833 133 0.057
Human Rat
cytokine production GO:0001816 319 0.056
regulation of t cell activation GO:0050863 170 0.056
leukocyte differentiation GO:0002521 342 0.054
regulation of t cell proliferation GO:0042129 92 0.053
cellular ketone metabolic process GO:0042180 84 0.051
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 5 0.050
Rat
peptide metabolic process GO:0006518 46 0.050
covalent chromatin modification GO:0016569 163 0.050
negative regulation of immune effector process GO:0002698 55 0.049
Rat
positive regulation of apoptotic signaling pathway GO:2001235 95 0.049
molting cycle GO:0042303 90 0.048
nitrogen compound transport GO:0071705 271 0.048
Human Rat
negative regulation of lymphocyte activation GO:0051250 91 0.047
dna metabolic process GO:0006259 303 0.046
extrinsic apoptotic signaling pathway GO:0097191 126 0.045
t helper 17 cell lineage commitment GO:0072540 4 0.045
tolerance induction dependent upon immune response GO:0002461 1 0.044
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.044
Rat
chromatin organization GO:0006325 206 0.044
heterocycle catabolic process GO:0046700 280 0.043
Rat
anion transport GO:0006820 177 0.043
transport of virus GO:0046794 1 0.043
Human
multicellular organismal iron ion homeostasis GO:0060586 8 0.043
ribonucleotide metabolic process GO:0009259 291 0.042
Rat
negative regulation of cell proliferation GO:0008285 296 0.042
positive regulation of interferon alpha production GO:0032727 4 0.042
regulation of cellular amine metabolic process GO:0033238 20 0.041
cellular amine metabolic process GO:0044106 44 0.041
metal ion homeostasis GO:0055065 189 0.041
organic cyclic compound catabolic process GO:1901361 295 0.041
Rat
positive regulation of hydrolase activity GO:0051345 148 0.039
inorganic cation import into cell GO:0098659 4 0.038
sequestering of calcium ion GO:0051208 18 0.038
cellular protein complex assembly GO:0043623 116 0.038
Worm
negative regulation of leukocyte differentiation GO:1902106 51 0.038
modification dependent protein catabolic process GO:0019941 133 0.037
cellular response to dna damage stimulus GO:0006974 207 0.036
compound eye development GO:0048749 1 0.036
regulation of cellular amino acid metabolic process GO:0006521 5 0.036
positive regulation of type i interferon production GO:0032481 14 0.035
type i interferon production GO:0032606 29 0.035
leukocyte proliferation GO:0070661 172 0.035
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.034
hormone biosynthetic process GO:0042446 16 0.034
anatomical structure homeostasis GO:0060249 145 0.034
retina homeostasis GO:0001895 23 0.034
negative regulation of cell killing GO:0031342 8 0.034
Rat
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.034
Mouse
cytokine mediated signaling pathway GO:0019221 115 0.033
cation transmembrane transport GO:0098655 266 0.033
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.032
Human
gene silencing by rna GO:0031047 19 0.031
Worm
alpha beta t cell differentiation GO:0046632 69 0.031
purine nucleoside triphosphate metabolic process GO:0009144 226 0.031
Rat
epithelial tube morphogenesis GO:0060562 303 0.031
immunoglobulin production GO:0002377 73 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
myeloid dendritic cell differentiation GO:0043011 16 0.030
organic anion transport GO:0015711 137 0.030
lymphocyte proliferation GO:0046651 164 0.030
dephosphorylation GO:0016311 129 0.030
ribose phosphate metabolic process GO:0019693 291 0.030
Rat
cellular nitrogen compound catabolic process GO:0044270 280 0.030
Rat
transmembrane transport GO:0055085 412 0.029
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.029
regulation of leukocyte proliferation GO:0070663 121 0.029
protein catabolic process GO:0030163 221 0.029
oxidation reduction process GO:0055114 342 0.029
negative regulation of cell activation GO:0050866 111 0.028
purine containing compound metabolic process GO:0072521 311 0.028
Rat
somatic diversification of immune receptors GO:0002200 53 0.028
t cell activation involved in immune response GO:0002286 43 0.028
response to radiation GO:0009314 165 0.028
cell killing GO:0001906 67 0.027
Mouse Rat
somatic cell dna recombination GO:0016444 51 0.027
inorganic cation transmembrane transport GO:0098662 207 0.027
positive regulation of apoptotic process GO:0043065 217 0.027
epidermis development GO:0008544 187 0.027
cellular homeostasis GO:0019725 240 0.027
sequestering of metal ion GO:0051238 19 0.027
regulation of membrane potential GO:0042391 192 0.026
regulation of hormone levels GO:0010817 211 0.026
regulation of cellular ketone metabolic process GO:0010565 66 0.026
leukocyte apoptotic process GO:0071887 71 0.025
protein refolding GO:0042026 1 0.025
ras protein signal transduction GO:0007265 77 0.025
positive regulation of t cell activation GO:0050870 101 0.025
positive regulation of cytokine production GO:0001819 174 0.025
positive regulation of cell development GO:0010720 237 0.025
aromatic compound catabolic process GO:0019439 286 0.025
Rat
multicellular organismal homeostasis GO:0048871 164 0.024
purine ribonucleoside catabolic process GO:0046130 205 0.024
Rat
posttranscriptional gene silencing GO:0016441 10 0.024
Worm
negative regulation of interferon beta production GO:0032688 3 0.024
regulation of metal ion transport GO:0010959 106 0.024
ion transmembrane transport GO:0034220 361 0.024
regulation of fatty acid transport GO:2000191 10 0.024
regulation of cell cycle GO:0051726 281 0.024
ribonucleoside triphosphate catabolic process GO:0009203 199 0.024
Rat
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 36 0.024
negative regulation of nervous system development GO:0051961 156 0.024
cellular response to cytokine stimulus GO:0071345 189 0.024
glycoprotein metabolic process GO:0009100 116 0.023
regulation of cell activation GO:0050865 289 0.023
purine ribonucleotide catabolic process GO:0009154 208 0.023
Rat
macromolecule catabolic process GO:0009057 281 0.023
gland development GO:0048732 330 0.023
positive regulation of immune effector process GO:0002699 107 0.023
Mouse
cell activation involved in immune response GO:0002263 126 0.023
cation homeostasis GO:0055080 212 0.023
negative regulation of cytokine production GO:0001818 84 0.022
amine metabolic process GO:0009308 45 0.022
ribonucleoside metabolic process GO:0009119 245 0.022
Rat
muscle tissue development GO:0060537 308 0.022
purine nucleoside catabolic process GO:0006152 205 0.022
Rat
regulation of protein kinase activity GO:0045859 232 0.022
negative regulation of t cell activation GO:0050868 65 0.022
regulation of lymphocyte proliferation GO:0050670 117 0.022
regulation of cytokine biosynthetic process GO:0042035 59 0.021
glycosyl compound metabolic process GO:1901657 246 0.021
Rat
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.021
signal transduction in absence of ligand GO:0038034 55 0.021
chromatin modification GO:0016568 187 0.021
generation of precursor metabolites and energy GO:0006091 103 0.021
inflammatory response GO:0006954 244 0.020
nucleoside triphosphate metabolic process GO:0009141 230 0.020
Rat
peptidyl amino acid modification GO:0018193 336 0.020
pattern recognition receptor signaling pathway GO:0002221 47 0.020
dna recombination GO:0006310 92 0.020
cytokine production involved in immune response GO:0002367 34 0.020
positive regulation of tolerance induction dependent upon immune response GO:0002654 1 0.020
cd8 positive alpha beta t cell differentiation GO:0043374 9 0.020
response to drug GO:0042493 75 0.020
calcium ion transport GO:0006816 159 0.020
cytokine biosynthetic process GO:0042089 68 0.020
regulation of alpha beta t cell activation GO:0046634 53 0.020
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.019
leukocyte activation involved in immune response GO:0002366 126 0.019
myeloid leukocyte activation GO:0002274 83 0.019
monocarboxylic acid transport GO:0015718 44 0.019
regulation of viral transcription GO:0046782 3 0.019
inorganic ion transmembrane transport GO:0098660 234 0.019
action potential GO:0001508 78 0.019
purine nucleoside triphosphate catabolic process GO:0009146 203 0.019
Rat
fatty acid derivative transport GO:1901571 14 0.019
cofactor transport GO:0051181 4 0.018
sensory perception GO:0007600 245 0.018
interleukin 13 secretion GO:0072611 2 0.018
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.018
regulation of organic acid transport GO:0032890 16 0.018
divalent metal ion transport GO:0070838 172 0.018
positive regulation of natural killer cell mediated immunity GO:0002717 16 0.018
nucleotide metabolic process GO:0009117 332 0.018
Rat
carbohydrate derivative catabolic process GO:1901136 231 0.018
Rat
histone modification GO:0016570 159 0.018
guanosine containing compound metabolic process GO:1901068 144 0.018
regulation of purine nucleotide metabolic process GO:1900542 169 0.018
cell type specific apoptotic process GO:0097285 268 0.018
skeletal system development GO:0001501 356 0.018
carboxylic acid transport GO:0046942 100 0.018
humoral immune response GO:0006959 57 0.017
positive regulation of gtp catabolic process GO:0033126 85 0.017
cdc42 protein signal transduction GO:0032488 0 0.017
respiratory system development GO:0060541 190 0.017
axonogenesis GO:0007409 274 0.017
mammary gland alveolus development GO:0060749 22 0.017
regulation of type i interferon mediated signaling pathway GO:0060338 7 0.017
establishment of organelle localization GO:0051656 122 0.017
stem cell development GO:0048864 219 0.017
immunoglobulin mediated immune response GO:0016064 69 0.017
regulation of immunoglobulin production GO:0002637 42 0.017
cytokine metabolic process GO:0042107 71 0.016
cellular response to biotic stimulus GO:0071216 92 0.016
small gtpase mediated signal transduction GO:0007264 97 0.016
alpha beta t cell activation involved in immune response GO:0002287 31 0.016
positive regulation of fever generation by positive regulation of prostaglandin secretion GO:0071812 2 0.016
cellular macromolecule catabolic process GO:0044265 206 0.016
intracellular protein transport GO:0006886 204 0.016
Human
engulfment of apoptotic cell GO:0043652 3 0.016
negative regulation of molecular function GO:0044092 258 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
positive regulation of protein modification process GO:0031401 299 0.016
mesenchyme development GO:0060485 152 0.016
immune response activating signal transduction GO:0002757 116 0.016
glycosylation GO:0070085 62 0.016
cellular chemical homeostasis GO:0055082 215 0.016
divalent inorganic cation transport GO:0072511 178 0.016
hatching GO:0035188 4 0.015
organic acid transport GO:0015849 101 0.015
positive regulation of cell migration GO:0030335 109 0.015
negative regulation of lymphocyte differentiation GO:0045620 32 0.015
ribonucleoside catabolic process GO:0042454 206 0.015
Rat
synaptic transmission GO:0007268 329 0.015
response to organonitrogen compound GO:0010243 246 0.015
regulation of anion transport GO:0044070 27 0.015
positive regulation of cell activation GO:0050867 158 0.015
positive regulation of lymphocyte activation GO:0051251 140 0.015
interleukin 1 production GO:0032612 31 0.015
bone development GO:0060348 120 0.015
mammary gland lobule development GO:0061377 22 0.015
morphogenesis of a branching structure GO:0001763 203 0.015
regulation of kinase activity GO:0043549 249 0.015
regulation of cell motility GO:2000145 236 0.015
regulation of homeostatic process GO:0032844 182 0.015
transition metal ion homeostasis GO:0055076 54 0.015
positive regulation of lymphocyte proliferation GO:0050671 70 0.015
response to interferon gamma GO:0034341 34 0.015
regulation of angiogenesis GO:0045765 81 0.015
regulation of syncytium formation by plasma membrane fusion GO:0060142 23 0.015
regulation of striated muscle cell differentiation GO:0051153 81 0.015
positive regulation of chemotaxis GO:0050921 38 0.015
negative regulation of cellular amine metabolic process GO:0033239 1 0.015
ameboidal type cell migration GO:0001667 128 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.014
sodium ion transport GO:0006814 73 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
positive regulation of b cell activation GO:0050871 49 0.014
neuron death GO:0070997 154 0.014
positive regulation of translational initiation GO:0045948 4 0.014
nitric oxide metabolic process GO:0046209 25 0.014
myd88 independent toll like receptor signaling pathway GO:0002756 3 0.014
interleukin 5 secretion GO:0072603 2 0.014
organonitrogen compound catabolic process GO:1901565 264 0.014
Rat
regulation of nucleotide metabolic process GO:0006140 169 0.014
regulation of nitric oxide biosynthetic process GO:0045428 18 0.014
skeletal muscle organ development GO:0060538 163 0.014
i kappab kinase nf kappab signaling GO:0007249 85 0.014
regulation of system process GO:0044057 200 0.014
lipid biosynthetic process GO:0008610 179 0.014
regulation of cellular catabolic process GO:0031329 242 0.014
maintenance of location GO:0051235 89 0.014
blood vessel morphogenesis GO:0048514 285 0.014
carbohydrate metabolic process GO:0005975 230 0.014
negative regulation of t cell differentiation GO:0045581 23 0.014
cellular ion homeostasis GO:0006873 165 0.014
positive regulation of cell death GO:0010942 224 0.014
regulation of cytokine secretion GO:0050707 61 0.014
regulation of interleukin 1 alpha production GO:0032650 4 0.014
negative regulation of phosphate metabolic process GO:0045936 184 0.014
leukocyte migration GO:0050900 124 0.014
b cell mediated immunity GO:0019724 71 0.013
keratinocyte differentiation GO:0030216 48 0.013
positive regulation of secretion by cell GO:1903532 114 0.013
nucleoside triphosphate catabolic process GO:0009143 205 0.013
Rat
protein localization to nucleus GO:0034504 121 0.013
fatty acid transport GO:0015908 28 0.013
nitric oxide biosynthetic process GO:0006809 25 0.013
interferon gamma production GO:0032609 67 0.013
negative regulation of interleukin 5 secretion GO:2000663 1 0.013
negative regulation of protein modification process GO:0031400 163 0.013
divalent inorganic cation homeostasis GO:0072507 138 0.013
peptidyl tyrosine modification GO:0018212 145 0.013
negative regulation of odontogenesis GO:0042483 3 0.013
purine nucleoside monophosphate metabolic process GO:0009126 81 0.013
Rat
t cell differentiation GO:0030217 174 0.013
negative regulation of interleukin 10 secretion GO:2001180 2 0.013
positive regulation of syncytium formation by plasma membrane fusion GO:0060143 17 0.013
positive regulation of lipid transport GO:0032370 22 0.013
methylation GO:0032259 134 0.013
cd8 positive alpha beta t cell proliferation GO:0035740 1 0.013
positive regulation of kinase activity GO:0033674 155 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
cellular response to molecule of bacterial origin GO:0071219 83 0.013
nucleocytoplasmic transport GO:0006913 139 0.013
neuron apoptotic process GO:0051402 142 0.013
positive regulation of isotype switching GO:0045830 15 0.013
regulation of toll like receptor signaling pathway GO:0034121 20 0.012
myotube differentiation GO:0014902 105 0.012
negative regulation of defense response to virus by host GO:0050689 1 0.012
female sex differentiation GO:0046660 84 0.012
regulation of b cell activation GO:0050864 81 0.012
regulation of inflammatory response GO:0050727 147 0.012
renal system development GO:0072001 225 0.012
negative regulation of interleukin 5 production GO:0032714 4 0.012
regulation of skeletal muscle fiber development GO:0048742 36 0.012
endomembrane system organization GO:0010256 147 0.012
innate immune response activating signal transduction GO:0002758 50 0.012
translation GO:0006412 93 0.012
membrane organization GO:0061024 245 0.012
transmission of nerve impulse GO:0019226 76 0.012
t cell differentiation in thymus GO:0033077 77 0.012
regulation of organ morphogenesis GO:2000027 144 0.012
regulation of organelle organization GO:0033043 289 0.012
sodium ion transmembrane transport GO:0035725 49 0.012
nucleoside phosphate catabolic process GO:1901292 222 0.012
Rat
circadian temperature homeostasis GO:0060086 2 0.012
cell cycle g1 s phase transition GO:0044843 57 0.012
muscle contraction GO:0006936 101 0.012
calcium ion homeostasis GO:0055074 127 0.012
tissue homeostasis GO:0001894 115 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.012
regulation of antigen processing and presentation GO:0002577 10 0.012
multicellular organismal signaling GO:0035637 91 0.012
ossification GO:0001503 216 0.012
peptidyl lysine modification GO:0018205 77 0.012
glycoprotein biosynthetic process GO:0009101 89 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
Rat
cellular response to acid chemical GO:0071229 68 0.012
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.012
immunoglobulin secretion GO:0048305 17 0.011
regulation of translation GO:0006417 71 0.011
regulation of ion homeostasis GO:2000021 64 0.011
morphogenesis of a branching epithelium GO:0061138 193 0.011
purine ribonucleotide metabolic process GO:0009150 290 0.011
Rat
protein targeting GO:0006605 143 0.011
axon ensheathment GO:0008366 76 0.011
purine nucleoside metabolic process GO:0042278 241 0.011
Rat
neuronal action potential GO:0019228 54 0.011
regulation of icosanoid secretion GO:0032303 8 0.011
import into cell GO:0098657 8 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
immune response regulating signaling pathway GO:0002764 125 0.011
cellular divalent inorganic cation homeostasis GO:0072503 127 0.011
atp catabolic process GO:0006200 55 0.011
Rat
pallium development GO:0021543 120 0.011
macromolecule glycosylation GO:0043413 55 0.011
chemotaxis GO:0006935 247 0.011
nucleoside metabolic process GO:0009116 246 0.011
Rat
cell adhesion GO:0007155 329 0.011
cognition GO:0050890 149 0.011
organonitrogen compound biosynthetic process GO:1901566 192 0.011
response to protozoan GO:0001562 28 0.011
purine nucleotide catabolic process GO:0006195 211 0.011
Rat
regulation of cell adhesion GO:0030155 154 0.011
serine phosphorylation of stat protein GO:0042501 3 0.011
defense response to protozoan GO:0042832 25 0.011
lymphocyte differentiation GO:0030098 242 0.011
protein import into nucleus GO:0006606 95 0.011
regulation of neuron apoptotic process GO:0043523 122 0.011
cellular calcium ion homeostasis GO:0006874 119 0.011
nucleotide catabolic process GO:0009166 217 0.011
Rat
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.011
protein localization to membrane GO:0072657 108 0.011
positive regulation of interleukin 12 production GO:0032735 21 0.011
gene silencing GO:0016458 38 0.011
Worm
iron ion transport GO:0006826 17 0.011
hair follicle development GO:0001942 85 0.011
cellular lipid metabolic process GO:0044255 323 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
skeletal system morphogenesis GO:0048705 203 0.011
muscle fiber development GO:0048747 76 0.011
hematopoietic stem cell proliferation GO:0071425 13 0.011
regulation of cysteine type endopeptidase activity GO:2000116 65 0.011
axon guidance GO:0007411 141 0.010
spermatogenesis GO:0007283 284 0.010
regulation of interleukin 5 secretion GO:2000662 2 0.010
defense response to virus GO:0051607 68 0.010
cellular response to lipopolysaccharide GO:0071222 77 0.010
icosanoid transport GO:0071715 14 0.010
regulation of interleukin 12 production GO:0032655 30 0.010
multicellular organismal aging GO:0010259 24 0.010
modification dependent macromolecule catabolic process GO:0043632 133 0.010
male gamete generation GO:0048232 285 0.010
organelle localization GO:0051640 179 0.010
lymphocyte apoptotic process GO:0070227 54 0.010
establishment of vesicle localization GO:0051650 81 0.010

Tap1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.547
Human
disease of anatomical entity DOID:7 0 0.547
Human
primary immunodeficiency disease DOID:612 0 0.450
Human
severe combined immunodeficiency DOID:627 0 0.450
Human
combined t cell and b cell immunodeficiency DOID:628 0 0.450
Human
nervous system disease DOID:863 0 0.045
cancer DOID:162 0 0.021
disease of cellular proliferation DOID:14566 0 0.021
organ system cancer DOID:0050686 0 0.021
disease of metabolism DOID:0014667 0 0.019
central nervous system disease DOID:331 0 0.015
musculoskeletal system disease DOID:17 0 0.011
connective tissue disease DOID:65 0 0.011