|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.467
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.382
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.346
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.326
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.315
|
Human |
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.314
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.295
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.242
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.241
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.232
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.225
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.202
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.202
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.193
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.189
|
|
|
|
regulation of reproductive process
|
GO:2000241 |
66 |
0.180
|
Human |
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.180
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.180
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.180
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.172
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.171
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.169
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.164
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.164
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.161
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.155
|
Human |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.154
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.150
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.149
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.148
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.147
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.146
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.146
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.146
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.144
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.143
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.141
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.140
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.137
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.137
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.135
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.130
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.123
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.123
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.118
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.116
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.114
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.113
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.112
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.111
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.111
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.109
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.107
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.104
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.104
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.103
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.100
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.100
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.099
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.097
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.096
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.096
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.092
|
|
|
|
embryonic limb morphogenesis
|
GO:0030326 |
126 |
0.092
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.091
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.091
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.091
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.090
|
|
|
|
spinal cord development
|
GO:0021510 |
81 |
0.090
|
|
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.090
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.089
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.088
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.088
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.088
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.084
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.083
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.081
|
Human |
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.081
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
46 |
0.080
|
|
|
|
regulation of immunological synapse formation
|
GO:2000520 |
2 |
0.078
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.078
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.078
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.078
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.076
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.076
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.075
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.075
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.075
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.074
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.074
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.074
|
|
|
|
interleukin 1 production
|
GO:0032612 |
31 |
0.073
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.072
|
|
|
|
notch signaling pathway
|
GO:0007219 |
71 |
0.072
|
|
|
|
cell differentiation in spinal cord
|
GO:0021515 |
53 |
0.072
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.071
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.071
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.070
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.070
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.069
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.069
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.068
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.067
|
|
|
|
regulation of endothelial cell differentiation
|
GO:0045601 |
10 |
0.067
|
|
|
|
oligodendrocyte differentiation
|
GO:0048709 |
53 |
0.067
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.067
|
Human |
|
|
tube formation
|
GO:0035148 |
140 |
0.067
|
|
|
|
positive regulation of eosinophil migration
|
GO:2000418 |
2 |
0.066
|
|
|
|
regulation of monocyte chemotaxis
|
GO:0090025 |
3 |
0.065
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.065
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.065
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.065
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.065
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.064
|
|
|
|
lung morphogenesis
|
GO:0060425 |
50 |
0.063
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.063
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.063
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.063
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.063
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
70 |
0.062
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.062
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.061
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.061
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.061
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.061
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.061
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.060
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.059
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.059
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.059
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.058
|
|
|
|
muscle adaptation
|
GO:0043500 |
39 |
0.058
|
|
|
|
mesendoderm development
|
GO:0048382 |
3 |
0.058
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.057
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.057
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.056
|
|
|
|
regulation of muscle adaptation
|
GO:0043502 |
31 |
0.056
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.055
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.055
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.055
|
Human |
|
|
negative regulation of prostatic bud formation
|
GO:0060686 |
4 |
0.055
|
|
|
|
nephron development
|
GO:0072006 |
109 |
0.055
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.055
|
|
|
|
striated muscle hypertrophy
|
GO:0014897 |
24 |
0.055
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.054
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.054
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.054
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.054
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.054
|
|
|
|
muscle hypertrophy
|
GO:0014896 |
24 |
0.054
|
|
|
|
regulation of eosinophil migration
|
GO:2000416 |
2 |
0.054
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.054
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.053
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.053
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.053
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
59 |
0.053
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.052
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.052
|
|
|
|
regulation of epidermis development
|
GO:0045682 |
33 |
0.051
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.051
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.051
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.050
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.050
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.050
|
Human |
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.050
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.050
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.049
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.049
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.048
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.048
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.048
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
88 |
0.048
|
Human |
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.048
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.047
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.047
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.046
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.046
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.046
|
|
|
|
potassium ion transmembrane transport
|
GO:0071805 |
43 |
0.046
|
|
|
|
roof plate formation
|
GO:0021509 |
1 |
0.046
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.045
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.045
|
|
|
|
neuroepithelial cell differentiation
|
GO:0060563 |
37 |
0.045
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.045
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.045
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.044
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.044
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.044
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.044
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.044
|
|
|
|
cardiac muscle hypertrophy
|
GO:0003300 |
23 |
0.044
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.044
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.044
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.043
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.043
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
43 |
0.043
|
|
|
|
lipid transport
|
GO:0006869 |
98 |
0.043
|
Human |
|
|
mesonephric tubule development
|
GO:0072164 |
94 |
0.043
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.043
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.043
|
|
|
|
ovarian follicle development
|
GO:0001541 |
40 |
0.042
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.042
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.042
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.042
|
|
|
|
mesodermal cell fate specification
|
GO:0007501 |
11 |
0.042
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.041
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.041
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.041
|
|
|
|
eosinophil migration
|
GO:0072677 |
3 |
0.041
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.041
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
23 |
0.041
|
|
|
|
t helper 17 cell chemotaxis
|
GO:0035705 |
1 |
0.040
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.040
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.040
|
|
|
|
heart trabecula morphogenesis
|
GO:0061384 |
26 |
0.039
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.039
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.039
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.039
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
78 |
0.039
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.039
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.039
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.039
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.038
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.038
|
Human |
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.038
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.038
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.038
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.038
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.038
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.038
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.037
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.037
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.037
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.037
|
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.037
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.037
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.037
|
|
|
|
regulation of receptor activity
|
GO:0010469 |
41 |
0.037
|
|
|
|
mucopolysaccharide metabolic process
|
GO:1903510 |
25 |
0.037
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.036
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.036
|
|
|
|
male sex differentiation
|
GO:0046661 |
109 |
0.036
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.036
|
|
|
|
digestion
|
GO:0007586 |
40 |
0.036
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.036
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.036
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.036
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.036
|
|
|
|
polarity specification of proximal distal axis
|
GO:0010085 |
2 |
0.036
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.036
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.036
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.036
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.035
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.035
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.035
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.035
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.035
|
|
|
|
ventral spinal cord development
|
GO:0021517 |
48 |
0.035
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
49 |
0.035
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.035
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
126 |
0.034
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
44 |
0.034
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.034
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.034
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.034
|
Human |
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.034
|
|
|
|
determination of left right symmetry
|
GO:0007368 |
80 |
0.034
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.034
|
|
|
|
acetylcholine secretion neurotransmission
|
GO:0014055 |
2 |
0.034
|
|
|
|
limb development
|
GO:0060173 |
166 |
0.034
|
|
|
|
regulation of kidney development
|
GO:0090183 |
40 |
0.034
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.034
|
|
|
|
metanephros development
|
GO:0001656 |
79 |
0.034
|
|
|
|
cell cell recognition
|
GO:0009988 |
44 |
0.034
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.034
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.033
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.033
|
|
|
|
regulation of epidermal cell differentiation
|
GO:0045604 |
21 |
0.033
|
|
|
|
male gonad development
|
GO:0008584 |
88 |
0.033
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.033
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.033
|
|
|
|
lung alveolus development
|
GO:0048286 |
45 |
0.033
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.033
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.033
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.033
|
|
|
|
chondrocyte differentiation
|
GO:0002062 |
72 |
0.033
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.033
|
|
|
|
regulation of notch signaling pathway
|
GO:0008593 |
35 |
0.033
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.032
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.032
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.032
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
27 |
0.032
|
|
|
|
proteoglycan metabolic process
|
GO:0006029 |
38 |
0.032
|
|
|
|
smoothened signaling pathway
|
GO:0007224 |
105 |
0.032
|
|
|
|
negative regulation of eosinophil degranulation
|
GO:0043310 |
1 |
0.032
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
100 |
0.031
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.031
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.031
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.031
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.031
|
|
|
|
microglial cell activation involved in immune response
|
GO:0002282 |
1 |
0.031
|
|
|
|
response to sterol
|
GO:0036314 |
4 |
0.031
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.031
|
|
|
|
development of primary female sexual characteristics
|
GO:0046545 |
73 |
0.031
|
Human |
|
|
regulation of keratinocyte differentiation
|
GO:0045616 |
11 |
0.031
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.031
|
|
|
|
mesoderm development
|
GO:0007498 |
100 |
0.030
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.030
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.030
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.030
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.030
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.030
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.030
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.030
|
|
|
|
dendritic cell differentiation
|
GO:0097028 |
26 |
0.030
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.030
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.030
|
Human |
|
|
immune effector process
|
GO:0002252 |
321 |
0.029
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
65 |
0.029
|
|
|
|
oocyte development
|
GO:0048599 |
33 |
0.029
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.029
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.029
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.029
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.029
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.029
|
|
|
|
development of primary male sexual characteristics
|
GO:0046546 |
88 |
0.029
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
87 |
0.029
|
|
|
|
mesonephros development
|
GO:0001823 |
97 |
0.029
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.029
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.028
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.028
|
|
|
|
negative regulation of cholesterol transport
|
GO:0032375 |
4 |
0.028
|
|
|
|
potassium ion transport
|
GO:0006813 |
52 |
0.028
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.028
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.028
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.028
|
|
|
|
tendon formation
|
GO:0035992 |
4 |
0.028
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.028
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.028
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
54 |
0.028
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.028
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.028
|
|
|
|
activation of transmembrane receptor protein tyrosine kinase activity
|
GO:0007171 |
3 |
0.028
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.028
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.028
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.028
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.028
|
|
|
|
cartilage development
|
GO:0051216 |
140 |
0.027
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.027
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.027
|
|
|
|
forelimb morphogenesis
|
GO:0035136 |
40 |
0.027
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.027
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
91 |
0.027
|
|
|
|
positive regulation of immunological synapse formation
|
GO:2000522 |
1 |
0.027
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.027
|
|
|
|
limb morphogenesis
|
GO:0035108 |
149 |
0.027
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.027
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
70 |
0.027
|
|
|
|
sensory perception of pain
|
GO:0019233 |
47 |
0.027
|
|
|
|
feeding behavior
|
GO:0007631 |
62 |
0.027
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.027
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.026
|
|
|
|
activin receptor signaling pathway
|
GO:0032924 |
18 |
0.026
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.026
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.026
|
|
|
|
regulation of stem cell proliferation
|
GO:0072091 |
78 |
0.026
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.026
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.026
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.026
|
|
|
|
cell proliferation involved in kidney development
|
GO:0072111 |
14 |
0.026
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.026
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.026
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.026
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.026
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.026
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.026
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.026
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
29 |
0.026
|
|
|
|
regulation of interleukin 1 production
|
GO:0032652 |
26 |
0.026
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.025
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.025
|
|
|
|
lateral mesoderm development
|
GO:0048368 |
13 |
0.025
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.025
|
|
|
|
thymocyte migration
|
GO:0072679 |
2 |
0.025
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.025
|
|
|
|
regulation of cartilage development
|
GO:0061035 |
44 |
0.025
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.025
|
|
|
|
positive regulation of glial cell differentiation
|
GO:0045687 |
21 |
0.025
|
|
|
|
ureteric bud development
|
GO:0001657 |
94 |
0.025
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.025
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.025
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.025
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.025
|
|
|
|
left lung development
|
GO:0060459 |
4 |
0.025
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.025
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.025
|
|
|
|
mesonephric epithelium development
|
GO:0072163 |
94 |
0.025
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.025
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.025
|
|
|
|
metanephric mesenchyme morphogenesis
|
GO:0072133 |
4 |
0.025
|
|
|
|
negative regulation of macrophage apoptotic process
|
GO:2000110 |
3 |
0.025
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.025
|
|
|
|
ceramide biosynthetic process
|
GO:0046513 |
20 |
0.024
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.024
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.024
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.024
|
|
|
|
regulation of hematopoietic stem cell migration
|
GO:2000471 |
1 |
0.024
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.024
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.024
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.024
|
|
|
|
positive regulation of monocyte extravasation
|
GO:2000439 |
1 |
0.024
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
43 |
0.024
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.024
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.024
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.024
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.024
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.024
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
77 |
0.024
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.024
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.024
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.024
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.024
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.023
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.023
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.023
|
|
|
|
trabecula morphogenesis
|
GO:0061383 |
40 |
0.023
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.023
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.023
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.023
|
|
|
|
thymus development
|
GO:0048538 |
41 |
0.023
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.023
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.023
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.023
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.023
|
|
|
|
negative regulation of sterol transport
|
GO:0032372 |
4 |
0.023
|
|
|
|
hematopoietic stem cell migration
|
GO:0035701 |
1 |
0.023
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.023
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.023
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.023
|
|
|
|
regulation of thymocyte migration
|
GO:2000410 |
2 |
0.023
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.023
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.023
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.023
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.022
|
|
|
|
appendage development
|
GO:0048736 |
166 |
0.022
|
|
|
|
positive regulation of endothelial cell proliferation
|
GO:0001938 |
17 |
0.022
|
|
|
|
camp metabolic process
|
GO:0046058 |
40 |
0.022
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.022
|
|
|
|
floor plate morphogenesis
|
GO:0033505 |
3 |
0.022
|
|
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.022
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.022
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.022
|
|
|
|
mature dendritic cell differentiation
|
GO:0097029 |
3 |
0.022
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.022
|
|
|
|
oocyte maturation
|
GO:0001556 |
18 |
0.022
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.022
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.022
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.022
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.022
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.022
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.022
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
93 |
0.021
|
|
|
|
eosinophil activation
|
GO:0043307 |
1 |
0.021
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.021
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.021
|
|
|
|
positive regulation of cyclic nucleotide metabolic process
|
GO:0030801 |
24 |
0.021
|
|
|
|
detection of stimulus
|
GO:0051606 |
84 |
0.021
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.021
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.021
|
|
|
|
regulation of tube size
|
GO:0035150 |
57 |
0.021
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.021
|
|
|
|
positive regulation of endothelial cell differentiation
|
GO:0045603 |
7 |
0.021
|
|
|
|
nephron morphogenesis
|
GO:0072028 |
69 |
0.021
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.021
|
|
|
|
female gonad development
|
GO:0008585 |
71 |
0.021
|
Human |
|
|
innate immune response
|
GO:0045087 |
157 |
0.021
|
|
|
|
hormone biosynthetic process
|
GO:0042446 |
16 |
0.021
|
|
|
|
odontogenesis
|
GO:0042476 |
78 |
0.021
|
|
|
|
stem cell division
|
GO:0017145 |
30 |
0.021
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.021
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.021
|
|
|
|
cell recognition
|
GO:0008037 |
83 |
0.021
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.021
|
|
|
|
regulation of calcium ion transmembrane transporter activity
|
GO:1901019 |
20 |
0.021
|
|
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
26 |
0.021
|
|
|
|
regulation of immune complex clearance by monocytes and macrophages
|
GO:0090264 |
2 |
0.021
|
|
|
|
t cell extravasation
|
GO:0072683 |
4 |
0.021
|
|
|
|
regulation of cardiac muscle tissue development
|
GO:0055024 |
31 |
0.021
|
|
|
|
apoptotic process involved in development
|
GO:1902742 |
28 |
0.021
|
|
|
|
visual learning
|
GO:0008542 |
44 |
0.020
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.020
|
|
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
87 |
0.020
|
|
|
|
insulin secretion
|
GO:0030073 |
89 |
0.020
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.020
|
|
|
|
regulation of timing of cell differentiation
|
GO:0048505 |
11 |
0.020
|
|
