IMP

Process View

Mus musculus

10 genes annotated in mouse

Multi-species View

regulation of endothelial cell differentiation

GO:0045601

Any process that modulates the frequency, rate or extent of endothelial cell differentiation.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of endothelial cell differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of endothelial cell differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.997	Mouse
Tgfbr2	transforming growth factor, beta receptor II	0.904	Mouse
Flt4	FMS-like tyrosine kinase 4	0.851	Mouse
Kdr	kinase insert domain protein receptor	0.838
Apc	adenomatosis polyposis coli	0.780
Smad4	MAD homolog 4 (Drosophila)	0.698
Ctnnb1	catenin (cadherin associated protein), beta 1	0.693
Bmp4	bone morphogenetic protein 4	0.596
Acvr1	activin A receptor, type 1	0.533	Mouse
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.479
Nos3	nitric oxide synthase 3, endothelial cell	0.437
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.423	Mouse
Vegfa	vascular endothelial growth factor A	0.408
Ptch1	patched homolog 1	0.394
Foxc1	forkhead box C1	0.389
Smad3	MAD homolog 3 (Drosophila)	0.385
Fgfr2	fibroblast growth factor receptor 2	0.338
S1pr3	sphingosine-1-phosphate receptor 3	0.331	Human
Ikzf1	IKAROS family zinc finger 1	0.316
Psen1	presenilin 1	0.315
Csf1	colony stimulating factor 1 (macrophage)	0.305
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.279
Nodal	nodal	0.276	Mouse
Meox2	mesenchyme homeobox 2	0.246
Pdgfb	platelet derived growth factor, B polypeptide	0.241	Mouse
Pten	phosphatase and tensin homolog	0.232
Tgfb1	transforming growth factor, beta 1	0.214
She	src homology 2 domain-containing transforming protein E	0.211
Eng	endoglin	0.203
Smad6	MAD homolog 6 (Drosophila)	0.201
Bmp7	bone morphogenetic protein 7	0.180	Mouse
Bmp2	bone morphogenetic protein 2	0.154	Mouse
Src	Rous sarcoma oncogene	0.152
Fgfr3	fibroblast growth factor receptor 3	0.128
Smad7	MAD homolog 7 (Drosophila)	0.128
Kcnq1	potassium voltage-gated channel, subfamily Q, member 1	0.121
Prrx1	paired related homeobox 1	0.120
Gdf1	growth differentiation factor 1	0.112	Mouse
Tgfb2	transforming growth factor, beta 2	0.112
Tbx2	T-box 2	0.106
Erbb2ip	Erbb2 interacting protein	0.106
Atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.101
Shh	sonic hedgehog	0.098
Elk3	ELK3, member of ETS oncogene family	0.095
Foxc2	forkhead box C2	0.093
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.089
Cdh5	cadherin 5	0.086
Gja1	gap junction protein, alpha 1	0.085
Gdf3	growth differentiation factor 3	0.084	Mouse
Sox7	SRY-box containing gene 7	0.082
Kif3a	kinesin family member 3A	0.080
Etv4	ets variant gene 4 (E1A enhancer binding protein, E1AF)	0.076	Mouse
Notch1	Notch gene homolog 1 (Drosophila)	0.075	Mouse Rat
Fzd7	frizzled homolog 7 (Drosophila)	0.071
Hic1	hypermethylated in cancer 1	0.070
Foxd3	forkhead box D3	0.069
Gdf9	growth differentiation factor 9	0.067
Fgfr1	fibroblast growth factor receptor 1	0.064
Notch2	Notch gene homolog 2 (Drosophila)	0.064	Mouse
Kit	kit oncogene	0.064	Mouse
Tgfbr3	transforming growth factor, beta receptor III	0.059
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.058	Mouse
Hand2	heart and neural crest derivatives expressed transcript 2	0.056
Hoxd13	homeobox D13	0.056
Epas1	endothelial PAS domain protein 1	0.056
Ptprb	protein tyrosine phosphatase, receptor type, B	0.052
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.052
Sox9	SRY-box containing gene 9	0.050
Sox18	SRY-box containing gene 18	0.047
Arap3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	0.047
Kiss1	KiSS-1 metastasis-suppressor	0.045
Itga8	integrin alpha 8	0.045
Ldlr	low density lipoprotein receptor	0.045
Jmjd1c	jumonji domain containing 1C	0.042
Tdgf1	teratocarcinoma-derived growth factor 1	0.040
Thbd	thrombomodulin	0.039
Gli3	GLI-Kruppel family member GLI3	0.039
Zfp36l1	zinc finger protein 36, C3H type-like 1	0.038
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.037
Wnt4	wingless-related MMTV integration site 4	0.037
Sox13	SRY-box containing gene 13	0.035
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.034
Cbl	Casitas B-lineage lymphoma	0.033
Dll1	delta-like 1 (Drosophila)	0.033
Tcf15	transcription factor 15	0.032
Tie1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.032
Runx2	runt related transcription factor 2	0.031
Chrd	chordin	0.031
Ret	ret proto-oncogene	0.031
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.031
Gata4	GATA binding protein 4	0.031
Flt1	FMS-like tyrosine kinase 1	0.030	Mouse
Gli1	GLI-Kruppel family member GLI1	0.030
Zfp503	zinc finger protein 503	0.030
Jag1	jagged 1	0.030
Smad1	MAD homolog 1 (Drosophila)	0.030
Fmn1	formin 1	0.028
Fli1	Friend leukemia integration 1	0.028
Gata6	GATA binding protein 6	0.027
Fgf8	fibroblast growth factor 8	0.027
Aplnr	apelin receptor	0.027
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.026
Fshr	follicle stimulating hormone receptor	0.026
Spry4	sprouty homolog 4 (Drosophila)	0.026
Gaa	glucosidase, alpha, acid	0.025
Fzd4	frizzled homolog 4 (Drosophila)	0.025
Ctnna1	catenin (cadherin associated protein), alpha 1	0.024
Bptf	bromodomain PHD finger transcription factor	0.024
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.024
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.024	Mouse
Ltbp3	latent transforming growth factor beta binding protein 3	0.023
Hes1	hairy and enhancer of split 1 (Drosophila)	0.023
Cacnb2	calcium channel, voltage-dependent, beta 2 subunit	0.022
S1pr2	sphingosine-1-phosphate receptor 2	0.022	Human
Efnb1	ephrin B1	0.022
Hoxb6	homeobox B6	0.022
Foxf1a	forkhead box F1a	0.022
Jag2	jagged 2	0.021
Psen2	presenilin 2	0.021
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.021
Emp2	epithelial membrane protein 2	0.021
Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.021
Mcam	melanoma cell adhesion molecule	0.020
Gpc3	glypican 3	0.020
Sox17	SRY-box containing gene 17	0.020
Ush1g	Usher syndrome 1G homolog (human)	0.020
Rasip1	Ras interacting protein 1	0.019
Cmklr1	chemokine-like receptor 1	0.019
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.019
Ldb2	LIM domain binding 2	0.019
Hand1	heart and neural crest derivatives expressed transcript 1	0.018
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.018
Trp53	transformation related protein 53	0.018
Hlx	H2.0-like homeobox	0.018
Grxcr1	glutaredoxin, cysteine rich 1	0.017
Zeb1	zinc finger E-box binding homeobox 1	0.017
Adrb1	adrenergic receptor, beta 1	0.017
Isl1	ISL1 transcription factor, LIM/homeodomain	0.017
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.017
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.016
Smo	smoothened homolog (Drosophila)	0.016
Gata1	GATA binding protein 1	0.016
Hoxa13	homeobox A13	0.015
Tgfbr1	transforming growth factor, beta receptor I	0.015	Mouse Rat
Hdac5	histone deacetylase 5	0.015
Tead2	TEA domain family member 2	0.015
Ptch2	patched homolog 2	0.015
Cxcl12	chemokine (C-X-C motif) ligand 12	0.014
Sdc3	syndecan 3	0.014
Yap1	yes-associated protein 1	0.014
Zic3	zinc finger protein of the cerebellum 3	0.014
Amhr2	anti-Mullerian hormone type 2 receptor	0.014	Mouse
Mapk12	mitogen-activated protein kinase 12	0.013
Fmnl3	formin-like 3	0.013
Gata2	GATA binding protein 2	0.013
Ltbp4	latent transforming growth factor beta binding protein 4	0.013
Tbx3	T-box 3	0.013
Prkg1	protein kinase, cGMP-dependent, type I	0.013
Gsk3b	glycogen synthase kinase 3 beta	0.013
Ednrb	endothelin receptor type B	0.013
Nf1	neurofibromatosis 1	0.012
Lama5	laminin, alpha 5	0.012
Ctnnbip1	catenin beta interacting protein 1	0.012
Mcl1	myeloid cell leukemia sequence 1	0.012
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.012
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.012
Fzd8	frizzled homolog 8 (Drosophila)	0.012
Socs5	suppressor of cytokine signaling 5	0.012
Spred1	sprouty protein with EVH-1 domain 1, related sequence	0.012
Cnga3	cyclic nucleotide gated channel alpha 3	0.012
Bmper	BMP-binding endothelial regulator	0.011
Bcl6b	B-cell CLL/lymphoma 6, member B	0.011
Foxh1	forkhead box H1	0.011
Adcy4	adenylate cyclase 4	0.011
F2r	coagulation factor II (thrombin) receptor	0.011
Pdgfa	platelet derived growth factor, alpha	0.011	Mouse
Wsb1	WD repeat and SOCS box-containing 1	0.011
Kcne1	potassium voltage-gated channel, Isk-related subfamily, member 1	0.011
Smtn	smoothelin	0.011
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.011
Tbx1	T-box 1	0.011
Bmp6	bone morphogenetic protein 6	0.011
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.011
Htt	huntingtin	0.011
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.010
Atn1	atrophin 1	0.010
Smad2	MAD homolog 2 (Drosophila)	0.010
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.010
Phlda3	pleckstrin homology-like domain, family A, member 3	0.010
Ramp2	receptor (calcitonin) activity modifying protein 2	0.010
Irs1	insulin receptor substrate 1	0.010
Pecam1	platelet/endothelial cell adhesion molecule 1	0.010
C1qtnf1	C1q and tumor necrosis factor related protein 1	0.010
Epor	erythropoietin receptor	0.010