Mus musculus

11 known processes

Psmb8

proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)

(Aliases: Lmp7,Lmp-7)

Psmb8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of t cell mediated cytotoxicity GO:0001916 15 1.000
negative regulation of natural killer cell mediated immunity GO:0002716 5 1.000
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway GO:0002484 3 0.998
antigen processing and presentation of peptide antigen via mhc class i GO:0002474 9 0.997
antigen processing and presentation via mhc class ib GO:0002475 8 0.997
regulation of t cell mediated cytotoxicity GO:0001914 18 0.993
antigen processing and presentation of endogenous peptide antigen via mhc class i GO:0019885 3 0.957
natural killer cell mediated cytotoxicity GO:0042267 29 0.934
antigen processing and presentation GO:0019882 47 0.932
antigen processing and presentation of exogenous antigen GO:0019884 26 0.928
t cell mediated cytotoxicity GO:0001913 26 0.916
antigen processing and presentation of endogenous peptide antigen via mhc class ib GO:0002476 4 0.903
antigen processing and presentation of peptide antigen via mhc class ib GO:0002428 5 0.883
regulation of myd88 independent toll like receptor signaling pathway GO:0034127 1 0.798
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.786
regulation of natural killer cell mediated cytotoxicity GO:0042269 19 0.745
innate immune response GO:0045087 157 0.696
antigen processing and presentation of peptide antigen GO:0048002 29 0.689
interspecies interaction between organisms GO:0044419 83 0.683
positive regulation of t cell mediated immunity GO:0002711 24 0.666
antigen processing and presentation of exogenous peptide antigen GO:0002478 21 0.664
regulation of defense response GO:0031347 233 0.656
antigen processing and presentation of endogenous peptide antigen GO:0002483 6 0.637
myosin filament organization GO:0031033 3 0.633
positive regulation of cell killing GO:0031343 33 0.616
lymphocyte mediated immunity GO:0002449 139 0.615
cell killing GO:0001906 67 0.598
viral life cycle GO:0019058 36 0.591
glycosyl compound catabolic process GO:1901658 206 0.581
iron ion import into cell GO:0097459 4 0.571
leukocyte mediated cytotoxicity GO:0001909 62 0.546
antigen processing and presentation of exogenous peptide antigen via mhc class ib GO:0002477 3 0.529
t cell mediated immunity GO:0002456 50 0.519
regulation of t cell mediated immunity GO:0002709 34 0.518
regulation of tolerance induction dependent upon immune response GO:0002652 1 0.507
lysosomal transport GO:0007041 10 0.504
ribonucleotide metabolic process GO:0009259 291 0.501
cd8 positive alpha beta t cell proliferation GO:0035740 1 0.474
natural killer cell mediated immunity GO:0002228 29 0.459
regulation of type i interferon mediated signaling pathway GO:0060338 7 0.434
adaptive immune response GO:0002250 155 0.424
leukocyte mediated immunity GO:0002443 174 0.411
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.391
posttranscriptional gene silencing GO:0016441 10 0.390
myosin filament assembly GO:0031034 2 0.369
nucleoside triphosphate metabolic process GO:0009141 230 0.351
immune effector process GO:0002252 321 0.344
response to interferon beta GO:0035456 22 0.343
purine containing compound catabolic process GO:0072523 213 0.334
antigen processing and presentation of endogenous peptide antigen via mhc class ib via er pathway GO:0002488 2 0.329
negative regulation of innate immune response GO:0045824 17 0.326
regulation of myd88 dependent toll like receptor signaling pathway GO:0034124 2 0.309
carbohydrate derivative catabolic process GO:1901136 231 0.307
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.300
cellular response to interferon gamma GO:0071346 25 0.299
antigen processing and presentation of endogenous antigen GO:0019883 6 0.295
regulation of cell killing GO:0031341 40 0.290
protection from natural killer cell mediated cytotoxicity GO:0042270 2 0.268
defense response to protozoan GO:0042832 25 0.268
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.264
purine ribonucleotide catabolic process GO:0009154 208 0.257
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.257
negative regulation of defense response to virus by host GO:0050689 1 0.255
glycosyl compound metabolic process GO:1901657 246 0.249
ribonucleoside triphosphate catabolic process GO:0009203 199 0.247
defense response to other organism GO:0098542 197 0.245
nucleobase containing small molecule metabolic process GO:0055086 352 0.242
negative regulation of defense response GO:0031348 77 0.235
regulation of cd8 positive alpha beta t cell activation GO:2001185 3 0.233
cellular component assembly involved in morphogenesis GO:0010927 139 0.232
purine nucleoside metabolic process GO:0042278 241 0.229
internal protein amino acid acetylation GO:0006475 42 0.229
cellular response to dna damage stimulus GO:0006974 207 0.221
ribose phosphate metabolic process GO:0019693 291 0.219
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.213
t cell proliferation GO:0042098 120 0.197
transport of virus GO:0046794 1 0.196
ribonucleoside triphosphate metabolic process GO:0009199 220 0.193
nucleotide metabolic process GO:0009117 332 0.187
organic cyclic compound catabolic process GO:1901361 295 0.186
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway tap dependent GO:0002485 3 0.184
purine nucleotide metabolic process GO:0006163 302 0.183
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.179
antigen processing and presentation of endogenous peptide antigen via mhc class ib via er pathway tap dependent GO:0002489 2 0.178
regulation of adaptive immune response GO:0002819 90 0.178
negative regulation of cell activation GO:0050866 111 0.178
aromatic compound catabolic process GO:0019439 286 0.177
regulation of natural killer cell mediated immunity GO:0002715 19 0.174
nucleoside phosphate metabolic process GO:0006753 338 0.174
rna interference GO:0016246 2 0.171
mammary gland epithelial cell differentiation GO:0060644 13 0.167
nucleoside triphosphate catabolic process GO:0009143 205 0.166
t cell activation GO:0042110 289 0.164
positive regulation of adaptive immune response GO:0002821 61 0.164
striated muscle myosin thick filament assembly GO:0071688 1 0.164
actin cytoskeleton organization GO:0030036 220 0.163
ribonucleoside catabolic process GO:0042454 206 0.163
purine nucleoside triphosphate catabolic process GO:0009146 203 0.161
nucleotide catabolic process GO:0009166 217 0.157
purine ribonucleoside metabolic process GO:0046128 241 0.156
organonitrogen compound catabolic process GO:1901565 264 0.154
organophosphate catabolic process GO:0046434 232 0.152
negative regulation of cell proliferation GO:0008285 296 0.152
cellular nitrogen compound catabolic process GO:0044270 280 0.151
organelle assembly GO:0070925 177 0.151
guanosine containing compound metabolic process GO:1901068 144 0.149
negative regulation of immune system process GO:0002683 209 0.148
heterocycle catabolic process GO:0046700 280 0.145
positive regulation of leukocyte mediated immunity GO:0002705 70 0.141
antigen processing and presentation of exogenous protein antigen via mhc class ib tap dependent GO:0002481 3 0.139
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.139
response to molecule of bacterial origin GO:0002237 143 0.135
ribonucleotide catabolic process GO:0009261 208 0.133
response to protozoan GO:0001562 28 0.132
intracellular transport of virus GO:0075733 1 0.129
nucleoside metabolic process GO:0009116 246 0.126
positive regulation of tolerance induction dependent upon immune response GO:0002654 1 0.125
regulation of defense response to virus by host GO:0050691 8 0.124
regulation of interferon alpha production GO:0032647 5 0.123
purine nucleoside catabolic process GO:0006152 205 0.121
positive regulation of innate immune response GO:0045089 80 0.118
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.111
intracellular protein transport GO:0006886 204 0.109
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.106
methylation GO:0032259 134 0.104
cellular response to molecule of bacterial origin GO:0071219 83 0.102
gene silencing GO:0016458 38 0.100
cd4 positive alpha beta t cell lineage commitment GO:0043373 6 0.100
positive regulation of cytokine production GO:0001819 174 0.098
positive regulation of interferon alpha production GO:0032727 4 0.094
response to metal ion GO:0010038 47 0.093
keratinocyte differentiation GO:0030216 48 0.093
positive regulation of rig i signaling pathway GO:1900246 1 0.091
positive regulation of response to cytokine stimulus GO:0060760 11 0.091
nucleoside phosphate catabolic process GO:1901292 222 0.089
positive regulation of peptidase activity GO:0010952 49 0.089
cellular macromolecule catabolic process GO:0044265 206 0.088
purine ribonucleoside catabolic process GO:0046130 205 0.088
regulation of lymphocyte mediated immunity GO:0002706 84 0.086
antigen processing and presentation of exogenous peptide antigen via mhc class i GO:0042590 6 0.086
positive regulation of proteolysis GO:0045862 85 0.083
negative regulation of immune effector process GO:0002698 55 0.082
leukocyte proliferation GO:0070661 172 0.082
ubiquitin dependent protein catabolic process GO:0006511 129 0.081
negative regulation of lymphocyte activation GO:0051250 91 0.080
purine nucleotide catabolic process GO:0006195 211 0.080
response to lipopolysaccharide GO:0032496 128 0.080
regulation of dna templated transcription initiation GO:2000142 7 0.079
modification dependent protein catabolic process GO:0019941 133 0.079
negative regulation of interferon beta production GO:0032688 3 0.076
cation transport GO:0006812 399 0.076
regulation of t cell activation GO:0050863 170 0.076
t helper 17 cell lineage commitment GO:0072540 4 0.076
ribonucleoside metabolic process GO:0009119 245 0.075
purine nucleoside triphosphate metabolic process GO:0009144 226 0.075
defense response to gram negative bacterium GO:0050829 28 0.075
regulation of cytoplasmic transport GO:1903649 112 0.074
regulation of multi organism process GO:0043900 111 0.074
protein catabolic process GO:0030163 221 0.072
iron ion homeostasis GO:0055072 36 0.071
negative regulation of lymphocyte mediated immunity GO:0002707 21 0.070
lymphocyte proliferation GO:0046651 164 0.070
gtp metabolic process GO:0046039 144 0.069
metal ion homeostasis GO:0055065 189 0.069
positive regulation of immune effector process GO:0002699 107 0.069
muscle cell development GO:0055001 133 0.069
iron ion import GO:0097286 5 0.068
purine ribonucleotide metabolic process GO:0009150 290 0.067
cytoplasmic transport GO:0016482 234 0.065
viral process GO:0016032 41 0.064
regulation of t cell proliferation GO:0042129 92 0.062
response to organic cyclic compound GO:0014070 198 0.062
striated muscle cell development GO:0055002 125 0.062
tolerance induction dependent upon immune response GO:0002461 1 0.059
regulation of cellular amine metabolic process GO:0033238 20 0.058
actomyosin structure organization GO:0031032 56 0.057
protein methylation GO:0006479 81 0.057
positive regulation of hydrolase activity GO:0051345 148 0.055
purine containing compound metabolic process GO:0072521 311 0.055
autophagy GO:0006914 45 0.055
defense response to bacterium GO:0042742 119 0.054
negative regulation of t cell activation GO:0050868 65 0.051
defense response to virus GO:0051607 68 0.051
peptidyl lysine methylation GO:0018022 29 0.050
posttranscriptional regulation of gene expression GO:0010608 155 0.049
multicellular organism growth GO:0035264 161 0.048
regulation of type i interferon production GO:0032479 22 0.047
female sex differentiation GO:0046660 84 0.047
macromolecule catabolic process GO:0009057 281 0.047
cation homeostasis GO:0055080 212 0.045
regulation of protein ubiquitination GO:0031396 52 0.045
epidermis development GO:0008544 187 0.045
regulation of intracellular protein transport GO:0033157 82 0.044
negative regulation of interferon beta biosynthetic process GO:0045358 1 0.043
histone modification GO:0016570 159 0.042
response to interferon gamma GO:0034341 34 0.042
covalent chromatin modification GO:0016569 163 0.042
positive t cell selection GO:0043368 23 0.042
cellular response to cytokine stimulus GO:0071345 189 0.042
positive regulation of defense response GO:0031349 124 0.041
regulation of innate immune response GO:0045088 91 0.041
cellular amino acid metabolic process GO:0006520 103 0.040
reactive nitrogen species metabolic process GO:2001057 0 0.040
amide transport GO:0042886 138 0.039
epithelial cell proliferation GO:0050673 174 0.039
regulation of lymphocyte activation GO:0051249 240 0.039
interaction with host GO:0051701 22 0.038
nucleoside catabolic process GO:0009164 206 0.037
lymphocyte activation involved in immune response GO:0002285 93 0.037
negative regulation of protein modification process GO:0031400 163 0.036
viral genome replication GO:0019079 17 0.036
transition metal ion homeostasis GO:0055076 54 0.035
cellular response to interferon beta GO:0035458 21 0.035
interleukin 1 production GO:0032612 31 0.035
regulation of interferon gamma production GO:0032649 57 0.034
regulation of proteolysis GO:0030162 164 0.033
regulation of endopeptidase activity GO:0052548 89 0.033
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 5 0.033
cytokine production GO:0001816 319 0.032
regulation of nucleotide metabolic process GO:0006140 169 0.032
muscle cell differentiation GO:0042692 261 0.032
positive regulation of type i interferon production GO:0032481 14 0.032
nitrogen compound transport GO:0071705 271 0.032
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.031
cellular protein complex assembly GO:0043623 116 0.031
import into cell GO:0098657 8 0.030
myofibril assembly GO:0030239 34 0.030
regulation of cellular ketone metabolic process GO:0010565 66 0.030
reactive oxygen species metabolic process GO:0072593 84 0.030
phagocytosis GO:0006909 66 0.029
type i interferon production GO:0032606 29 0.029
positive regulation of type i interferon mediated signaling pathway GO:0060340 4 0.028
regulation of cd8 positive alpha beta t cell proliferation GO:2000564 1 0.028
chromatin organization GO:0006325 206 0.028
regulation of autophagy GO:0010506 30 0.028
guanosine containing compound catabolic process GO:1901069 144 0.028
protein modification by small protein conjugation or removal GO:0070647 207 0.028
regulation of cytokine biosynthetic process GO:0042035 59 0.028
positive regulation of interferon gamma production GO:0032729 39 0.027
negative regulation of t cell differentiation GO:0045581 23 0.027
positive regulation of dna templated transcription initiation GO:2000144 5 0.027
pattern recognition receptor signaling pathway GO:0002221 47 0.026
response to radiation GO:0009314 165 0.026
ear development GO:0043583 200 0.026
regulation of metal ion transport GO:0010959 106 0.026
regulation of hydrolase activity GO:0051336 246 0.026
regulation of interleukin 1 alpha production GO:0032650 4 0.026
transcription initiation from rna polymerase ii promoter GO:0006367 8 0.026
atp metabolic process GO:0046034 75 0.025
reactive oxygen species biosynthetic process GO:1903409 8 0.025
positive regulation of cellular component biogenesis GO:0044089 94 0.025
purine nucleoside monophosphate metabolic process GO:0009126 81 0.025
myd88 independent toll like receptor signaling pathway GO:0002756 3 0.025
modification dependent macromolecule catabolic process GO:0043632 133 0.025
regulation of response to biotic stimulus GO:0002831 38 0.025
regulation of reactive oxygen species metabolic process GO:2000377 40 0.025
negative regulation of protein metabolic process GO:0051248 282 0.024
negative regulation of necroptotic process GO:0060546 9 0.024
gtp catabolic process GO:0006184 143 0.024
regulation of intracellular transport GO:0032386 159 0.024
muscle tissue development GO:0060537 308 0.024
negative regulation of phosphorylation GO:0042326 166 0.023
apoptotic signaling pathway GO:0097190 306 0.023
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.023
t helper 17 cell differentiation GO:0072539 7 0.022
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 5 0.022
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.022
peptide transport GO:0015833 133 0.022
regulation of leukocyte mediated immunity GO:0002703 104 0.022
interferon beta production GO:0032608 16 0.022
leukocyte activation involved in immune response GO:0002366 126 0.022
negative regulation of phosphorus metabolic process GO:0010563 184 0.021
protein polymerization GO:0051258 57 0.021
macromolecule methylation GO:0043414 120 0.021
regulation of membrane potential GO:0042391 192 0.021
positive regulation of cellular amine metabolic process GO:0033240 5 0.021
chromatin modification GO:0016568 187 0.021
leukocyte differentiation GO:0002521 342 0.021
regulation of vasculature development GO:1901342 88 0.021
response to type i interferon GO:0034340 12 0.021
cd8 positive alpha beta t cell differentiation GO:0043374 9 0.020
regulation of protein transport GO:0051223 163 0.020
sensory system development GO:0048880 3 0.020
inflammatory response GO:0006954 244 0.020
syncytium formation GO:0006949 43 0.020
alpha beta t cell activation GO:0046631 91 0.020
blood vessel morphogenesis GO:0048514 285 0.020
negative regulation of cellular amine metabolic process GO:0033239 1 0.020
respiratory system development GO:0060541 190 0.020
regulation of peptidase activity GO:0052547 96 0.020
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.020
glycoprotein metabolic process GO:0009100 116 0.020
lymphocyte differentiation GO:0030098 242 0.020
cellular response to interferon alpha GO:0035457 4 0.020
pyrimidine containing compound catabolic process GO:0072529 3 0.019
regulation of hormone levels GO:0010817 211 0.019
regulation of cellular catabolic process GO:0031329 242 0.019
cellular amine metabolic process GO:0044106 44 0.019
central nervous system neuron differentiation GO:0021953 162 0.019
sequestering of metal ion GO:0051238 19 0.019
regulation of alpha beta t cell proliferation GO:0046640 18 0.018
cellular protein catabolic process GO:0044257 155 0.018
ribonucleoside monophosphate metabolic process GO:0009161 80 0.018
maintenance of location GO:0051235 89 0.018
regulation of lymphocyte proliferation GO:0050670 117 0.018
negative regulation of cell killing GO:0031342 8 0.018
cellular response to hormone stimulus GO:0032870 150 0.018
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.018
inorganic cation import into cell GO:0098659 4 0.018
b cell activation GO:0042113 161 0.017
regulation of protein localization GO:0032880 231 0.017
male gamete generation GO:0048232 285 0.017
negative regulation of cellular protein metabolic process GO:0032269 247 0.017
syncytium formation by plasma membrane fusion GO:0000768 42 0.017
cell fate commitment GO:0045165 210 0.017
proteasomal protein catabolic process GO:0010498 98 0.017
ras protein signal transduction GO:0007265 77 0.017
regulation of neuron apoptotic process GO:0043523 122 0.017
immunoglobulin mediated immune response GO:0016064 69 0.017
dephosphorylation GO:0016311 129 0.017
protein acylation GO:0043543 64 0.017
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.017
regulation of purine nucleotide metabolic process GO:1900542 169 0.017
cellular homeostasis GO:0019725 240 0.017
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.017
response to dsrna GO:0043331 30 0.017
negative regulation of t cell proliferation GO:0042130 38 0.017
ribonucleoside monophosphate catabolic process GO:0009158 57 0.017
calcium ion transport GO:0006816 159 0.017
regulation of cytokine production GO:0001817 266 0.017
cell adhesion GO:0007155 329 0.016
negative regulation of regulatory t cell differentiation GO:0045590 2 0.016
cellular response to lipid GO:0071396 145 0.016
response to cadmium ion GO:0046686 8 0.016
gene silencing by rna GO:0031047 19 0.016
protein refolding GO:0042026 1 0.016
peptidyl lysine modification GO:0018205 77 0.016
defense response to gram positive bacterium GO:0050830 50 0.016
skin development GO:0043588 220 0.016
negative regulation of leukocyte mediated immunity GO:0002704 29 0.016
small gtpase mediated signal transduction GO:0007264 97 0.016
negative regulation of intracellular signal transduction GO:1902532 167 0.016
regulation of cell cycle GO:0051726 281 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
spermatogenesis GO:0007283 284 0.016
cellular response to ammonium ion GO:0071242 2 0.016
regulation of interferon beta biosynthetic process GO:0045357 4 0.016
negative regulation of epithelial cell proliferation GO:0050680 64 0.016
peptide metabolic process GO:0006518 46 0.015
positive regulation of apoptotic signaling pathway GO:2001235 95 0.015
cellular metal ion homeostasis GO:0006875 151 0.015
negative regulation of intracellular protein transport GO:0090317 27 0.015
arp2 3 complex mediated actin nucleation GO:0034314 3 0.015
cellular ketone metabolic process GO:0042180 84 0.015
negative regulation of viral transcription GO:0032897 3 0.015
positive regulation of protein complex assembly GO:0031334 45 0.015
endocytosis GO:0006897 168 0.014
tube formation GO:0035148 140 0.014
hormone biosynthetic process GO:0042446 16 0.014
regulation of defense response to bacterium GO:1900424 3 0.014
lung development GO:0030324 164 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.014
protein kinase b signaling GO:0043491 74 0.014
neural tube development GO:0021915 160 0.014
epithelial tube formation GO:0072175 130 0.014
production of molecular mediator of immune response GO:0002440 103 0.014
interferon gamma production GO:0032609 67 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.014
regulation of dna binding GO:0051101 39 0.014
regulation of arp2 3 complex mediated actin nucleation GO:0034315 1 0.014
neuron apoptotic process GO:0051402 142 0.014
negative regulation of intracellular transport GO:0032387 38 0.014
protein ubiquitination GO:0016567 171 0.013
glucose homeostasis GO:0042593 128 0.013
epithelial tube morphogenesis GO:0060562 303 0.013
phagolysosome assembly GO:0001845 3 0.013
angiogenesis GO:0001525 201 0.013
neuron death GO:0070997 154 0.013
nucleocytoplasmic transport GO:0006913 139 0.013
morphogenesis of embryonic epithelium GO:0016331 159 0.013
positive regulation of antigen processing and presentation GO:0002579 10 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.013
posttranscriptional gene silencing by rna GO:0035194 10 0.013
regulation of chromosome organization GO:0033044 83 0.012
humoral immune response GO:0006959 57 0.012
regulation of lipid metabolic process GO:0019216 118 0.012
negative regulation of molecular function GO:0044092 258 0.012
myotube differentiation GO:0014902 105 0.012
protein oligomerization GO:0051259 67 0.012
engulfment of apoptotic cell GO:0043652 3 0.012
response to drug GO:0042493 75 0.012
pallium development GO:0021543 120 0.012
actin filament polymerization GO:0030041 44 0.012
striated muscle tissue development GO:0014706 293 0.012
t cell differentiation GO:0030217 174 0.012
nuclear transport GO:0051169 139 0.012
negative regulation of cell cycle GO:0045786 123 0.012
cellular divalent inorganic cation homeostasis GO:0072503 127 0.012
regulation of protein complex assembly GO:0043254 83 0.012
cellular response to type i interferon GO:0071357 10 0.012
regulation of organelle organization GO:0033043 289 0.012
response to organonitrogen compound GO:0010243 246 0.012
regulation of protein targeting GO:1903533 61 0.012
cellular chemical homeostasis GO:0055082 215 0.011
oxidation reduction process GO:0055114 342 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
response to inorganic substance GO:0010035 96 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.011
embryonic epithelial tube formation GO:0001838 130 0.011
response to light stimulus GO:0009416 135 0.011
carbohydrate homeostasis GO:0033500 128 0.011
positive regulation of actin nucleation GO:0051127 3 0.011
antimicrobial peptide biosynthetic process GO:0002777 2 0.011
transition metal ion transport GO:0000041 38 0.011
hair follicle development GO:0001942 85 0.011
macrophage migration inhibitory factor signaling pathway GO:0035691 2 0.011
mitochondrion organization GO:0007005 134 0.011
hormone metabolic process GO:0042445 86 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
renal system development GO:0072001 225 0.011
purine nucleoside monophosphate catabolic process GO:0009128 58 0.011
regulation of gtp catabolic process GO:0033124 113 0.011
connective tissue development GO:0061448 179 0.011
alpha beta t cell differentiation GO:0046632 69 0.010
cytokine secretion GO:0050663 72 0.010
positive regulation of interleukin 1 alpha secretion GO:0050717 3 0.010
peptidyl lysine acetylation GO:0018394 45 0.010
positive regulation of binding GO:0051099 49 0.010
cell substrate adhesion GO:0031589 130 0.010
cd4 positive or cd8 positive alpha beta t cell lineage commitment GO:0043369 8 0.010
protein import GO:0017038 101 0.010
regulation of system process GO:0044057 200 0.010
myeloid cell differentiation GO:0030099 233 0.010
rac protein signal transduction GO:0016601 13 0.010
response to peptide hormone GO:0043434 127 0.010
negative regulation of leukocyte differentiation GO:1902106 51 0.010
respiratory tube development GO:0030323 167 0.010
response to peptide GO:1901652 136 0.010
regulation of purine nucleotide catabolic process GO:0033121 122 0.010
regulation of neuron death GO:1901214 134 0.010

Psmb8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.234
disease of anatomical entity DOID:7 0 0.234
primary immunodeficiency disease DOID:612 0 0.180
combined t cell and b cell immunodeficiency DOID:628 0 0.180
severe combined immunodeficiency DOID:627 0 0.128
nervous system disease DOID:863 0 0.027
gastrointestinal system cancer DOID:3119 0 0.014
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014
respiratory system cancer DOID:0050615 0 0.014
lung cancer DOID:1324 0 0.014