Mus musculus

68 known processes

Srpx2

sushi-repeat-containing protein, X-linked 2

(Aliases: SRP,SRPUL,1110039C07Rik)

Srpx2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
extracellular structure organization GO:0043062 148 0.127
cell substrate adhesion GO:0031589 130 0.122
cellular response to growth factor stimulus GO:0071363 197 0.120
cellular ketone metabolic process GO:0042180 84 0.105
regulation of removal of superoxide radicals GO:2000121 4 0.103
extracellular matrix organization GO:0030198 147 0.092
oxidation reduction process GO:0055114 342 0.089
regulation of cellular ketone metabolic process GO:0010565 66 0.084
positive regulation of protein phosphorylation GO:0001934 242 0.066
regulation of secretion GO:0051046 274 0.062
regulation of hydrolase activity GO:0051336 246 0.062
positive regulation of protein modification process GO:0031401 299 0.061
regulation of cellular amino acid metabolic process GO:0006521 5 0.059
adiponectin secretion GO:0070162 2 0.059
cellular amino acid metabolic process GO:0006520 103 0.057
positive regulation of fatty acid oxidation GO:0046321 4 0.055
positive regulation of adiponectin secretion GO:0070165 1 0.054
cellular response to oxidative stress GO:0034599 76 0.053
spermatogenesis GO:0007283 284 0.053
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.052
regulation of cytokine production GO:0001817 266 0.051
regulation of cellular component biogenesis GO:0044087 181 0.049
Human
immune effector process GO:0002252 321 0.049
positive regulation of cytokine production GO:0001819 174 0.049
regulation of reactive oxygen species metabolic process GO:2000377 40 0.049
response to organonitrogen compound GO:0010243 246 0.049
reactive oxygen species metabolic process GO:0072593 84 0.047
ear development GO:0043583 200 0.045
regulation of hormone levels GO:0010817 211 0.044
cell adhesion GO:0007155 329 0.044
Human
connective tissue development GO:0061448 179 0.042
apoptotic signaling pathway GO:0097190 306 0.042
ras protein signal transduction GO:0007265 77 0.041
mapk cascade GO:0000165 281 0.040
fat cell differentiation GO:0045444 160 0.040
positive regulation of protein kinase activity GO:0045860 144 0.039
male gamete generation GO:0048232 285 0.039
regulation of adiponectin secretion GO:0070163 2 0.038
monocarboxylic acid metabolic process GO:0032787 191 0.038
innate immune response GO:0045087 157 0.038
positive regulation of cell adhesion GO:0045785 80 0.037
hormone secretion GO:0046879 128 0.037
small gtpase mediated signal transduction GO:0007264 97 0.036
response to oxidative stress GO:0006979 123 0.036
regulation of protein transport GO:0051223 163 0.036
response to growth factor GO:0070848 198 0.036
regulation of kinase activity GO:0043549 249 0.035
regulation of protein kinase activity GO:0045859 232 0.035
generation of precursor metabolites and energy GO:0006091 103 0.035
positive regulation of transferase activity GO:0051347 167 0.034
peptidyl amino acid modification GO:0018193 336 0.034
carbohydrate metabolic process GO:0005975 230 0.034
lung development GO:0030324 164 0.033
regulation of secretion by cell GO:1903530 249 0.033
cellular response to amino acid stimulus GO:0071230 29 0.033
positive regulation of cellular amine metabolic process GO:0033240 5 0.032
positive regulation of proteolysis GO:0045862 85 0.032
protein kinase b signaling GO:0043491 74 0.032
regulation of cell adhesion GO:0030155 154 0.031
regulation of cellular response to stress GO:0080135 159 0.031
gluconeogenesis GO:0006094 39 0.030
elastic fiber assembly GO:0048251 4 0.030
skeletal system development GO:0001501 356 0.030
regulation of cell substrate adhesion GO:0010810 73 0.030
negative regulation of phospholipase activity GO:0010519 4 0.030
cellular amine metabolic process GO:0044106 44 0.029
positive regulation of secretion by cell GO:1903532 114 0.029
cytokine production GO:0001816 319 0.029
positive regulation of kinase activity GO:0033674 155 0.028
fatty acid metabolic process GO:0006631 121 0.028
protein heterooligomerization GO:0051291 14 0.028
regulation of cell projection organization GO:0031344 206 0.028
developmental maturation GO:0021700 193 0.028
regulation of cell motility GO:2000145 236 0.028
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.027
extrinsic apoptotic signaling pathway GO:0097191 126 0.026
sensory organ morphogenesis GO:0090596 242 0.026
regulation of proteolysis GO:0030162 164 0.026
camera type eye development GO:0043010 266 0.026
rho protein signal transduction GO:0007266 32 0.025
regulation of transferase activity GO:0051338 263 0.025
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.025
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.025
response to inorganic substance GO:0010035 96 0.025
regulation of glycogen metabolic process GO:0070873 13 0.025
cellular response to acid chemical GO:0071229 68 0.024
regulation of peptidase activity GO:0052547 96 0.024
nitrogen compound transport GO:0071705 271 0.024
sensory perception of sound GO:0007605 97 0.024
positive regulation of cellular component biogenesis GO:0044089 94 0.024
Human
regulation of cellular amine metabolic process GO:0033238 20 0.024
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.023
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.023
carbohydrate biosynthetic process GO:0016051 74 0.023
positive regulation of nervous system development GO:0051962 221 0.023
Human
negative regulation of phosphate metabolic process GO:0045936 184 0.023
positive regulation of protein transport GO:0051222 93 0.023
cellular macromolecule catabolic process GO:0044265 206 0.023
ribose phosphate metabolic process GO:0019693 291 0.023
regulation of protein secretion GO:0050708 82 0.023
regulation of fatty acid oxidation GO:0046320 10 0.023
reactive oxygen species biosynthetic process GO:1903409 8 0.022
anatomical structure homeostasis GO:0060249 145 0.022
regulation of protein serine threonine kinase activity GO:0071900 157 0.022
regulation of mapk cascade GO:0043408 248 0.022
negative regulation of phosphorylation GO:0042326 166 0.022
regulation of map kinase activity GO:0043405 120 0.022
morphogenesis of embryonic epithelium GO:0016331 159 0.022
respiratory system development GO:0060541 190 0.022
lymphocyte mediated immunity GO:0002449 139 0.022
protein secretion GO:0009306 111 0.022
protein hydroxylation GO:0018126 4 0.022
energy derivation by oxidation of organic compounds GO:0015980 77 0.022
cellular lipid metabolic process GO:0044255 323 0.022
carbohydrate homeostasis GO:0033500 128 0.022
regulation of protein localization GO:0032880 231 0.021
negative regulation of cellular component organization GO:0051129 194 0.021
positive regulation of mapk cascade GO:0043410 170 0.021
activation of mapk activity GO:0000187 59 0.021
nucleobase containing small molecule metabolic process GO:0055086 352 0.021
regulation of fat cell differentiation GO:0045598 81 0.021
response to hypoxia GO:0001666 58 0.021
ossification GO:0001503 216 0.020
regulation of system process GO:0044057 200 0.020
defense response to bacterium GO:0042742 119 0.020
response to decreased oxygen levels GO:0036293 59 0.020
multicellular organismal homeostasis GO:0048871 164 0.020
positive regulation of defense response GO:0031349 124 0.020
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.020
developmental growth involved in morphogenesis GO:0060560 138 0.020
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.019
glucose homeostasis GO:0042593 128 0.019
skeletal system morphogenesis GO:0048705 203 0.019
endocrine process GO:0050886 39 0.019
antibacterial peptide biosynthetic process GO:0002780 2 0.019
positive regulation of apoptotic process GO:0043065 217 0.019
hexose biosynthetic process GO:0019319 39 0.019
cell type specific apoptotic process GO:0097285 268 0.019
amine metabolic process GO:0009308 45 0.019
negative regulation of fat cell differentiation GO:0045599 36 0.018
regulation of response to oxidative stress GO:1902882 19 0.018
positive regulation of cell death GO:0010942 224 0.018
heart morphogenesis GO:0003007 178 0.018
organophosphate biosynthetic process GO:0090407 122 0.018
response to molecule of bacterial origin GO:0002237 143 0.018
single organism cell adhesion GO:0098602 156 0.018
Human
positive regulation of hydrolase activity GO:0051345 148 0.018
endocytosis GO:0006897 168 0.018
physiological cardiac muscle hypertrophy GO:0003301 3 0.018
bone development GO:0060348 120 0.018
nucleoside phosphate metabolic process GO:0006753 338 0.018
response to amino acid GO:0043200 37 0.018
negative regulation of intracellular signal transduction GO:1902532 167 0.018
glycosyl compound metabolic process GO:1901657 246 0.017
organonitrogen compound biosynthetic process GO:1901566 192 0.017
negative regulation of cell development GO:0010721 169 0.017
cell matrix adhesion GO:0007160 68 0.017
lipid oxidation GO:0034440 29 0.017
response to organic cyclic compound GO:0014070 198 0.017
removal of superoxide radicals GO:0019430 12 0.017
nucleoside phosphate catabolic process GO:1901292 222 0.017
regulation of purine nucleotide catabolic process GO:0033121 122 0.017
regulation of cellular response to oxidative stress GO:1900407 19 0.017
negative regulation of cell proliferation GO:0008285 296 0.017
negative regulation of phosphorus metabolic process GO:0010563 184 0.017
lipid modification GO:0030258 65 0.017
heterocycle catabolic process GO:0046700 280 0.017
cellular glucan metabolic process GO:0006073 32 0.017
organ growth GO:0035265 117 0.017
synapse organization GO:0050808 125 0.017
Human
response to reactive oxygen species GO:0000302 56 0.017
nephron development GO:0072006 109 0.017
tissue homeostasis GO:0001894 115 0.017
collagen fibril organization GO:0030199 32 0.017
activation of immune response GO:0002253 138 0.017
negative regulation of cellular amine metabolic process GO:0033239 1 0.016
morphogenesis of a branching epithelium GO:0061138 193 0.016
positive regulation of cell substrate adhesion GO:0010811 47 0.016
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.016
monosaccharide biosynthetic process GO:0046364 44 0.016
urogenital system development GO:0001655 261 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
cellular nitrogen compound catabolic process GO:0044270 280 0.016
peptide transport GO:0015833 133 0.016
cation transport GO:0006812 399 0.016
amide transport GO:0042886 138 0.016
fibril organization GO:0097435 2 0.016
ribonucleotide metabolic process GO:0009259 291 0.016
erk1 and erk2 cascade GO:0070371 77 0.016
organelle localization GO:0051640 179 0.016
regulation of neuron differentiation GO:0045664 281 0.016
regulation of synapse assembly GO:0051963 29 0.016
Human
epithelial tube morphogenesis GO:0060562 303 0.016
purine containing compound metabolic process GO:0072521 311 0.015
engulfment of apoptotic cell GO:0043652 3 0.015
macromolecule catabolic process GO:0009057 281 0.015
intrinsic apoptotic signaling pathway GO:0097193 132 0.015
sulfur compound metabolic process GO:0006790 100 0.015
regulation of generation of precursor metabolites and energy GO:0043467 38 0.015
carbohydrate derivative biosynthetic process GO:1901137 183 0.015
endomembrane system organization GO:0010256 147 0.015
leukocyte migration GO:0050900 124 0.015
monosaccharide transport GO:0015749 58 0.015
positive regulation of hormone secretion GO:0046887 38 0.015
negative regulation of mapk cascade GO:0043409 65 0.015
negative regulation of apoptotic signaling pathway GO:2001234 104 0.015
signal transduction in absence of ligand GO:0038034 55 0.015
regulation of fatty acid metabolic process GO:0019217 28 0.015
negative regulation of molecular function GO:0044092 258 0.015
regulation of innate immune response GO:0045088 91 0.015
kidney morphogenesis GO:0060993 83 0.015
glucose transport GO:0015758 56 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.015
polysaccharide metabolic process GO:0005976 39 0.014
nephron tubule morphogenesis GO:0072078 68 0.014
stem cell differentiation GO:0048863 268 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
antimicrobial peptide biosynthetic process GO:0002777 2 0.014
glucose import GO:0046323 32 0.014
regulation of anatomical structure size GO:0090066 178 0.014
forebrain development GO:0030900 302 0.014
organic hydroxy compound metabolic process GO:1901615 203 0.014
peptide secretion GO:0002790 114 0.014
regulation of apoptotic signaling pathway GO:2001233 197 0.014
regulation of defense response GO:0031347 233 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
cartilage development GO:0051216 140 0.014
branching morphogenesis of an epithelial tube GO:0048754 159 0.014
reactive nitrogen species metabolic process GO:2001057 0 0.014
defense response to other organism GO:0098542 197 0.014
cellular protein complex assembly GO:0043623 116 0.014
regulation of muscle system process GO:0090257 80 0.014
fatty acid oxidation GO:0019395 28 0.014
response to oxygen levels GO:0070482 62 0.014
aromatic compound catabolic process GO:0019439 286 0.014
morphogenesis of a branching structure GO:0001763 203 0.014
positive regulation of protein secretion GO:0050714 52 0.013
cellular response to external stimulus GO:0071496 88 0.013
lipid biosynthetic process GO:0008610 179 0.013
carboxylic acid transport GO:0046942 100 0.013
cellular response to lipid GO:0071396 145 0.013
carbohydrate transport GO:0008643 62 0.013
regulation of neuron projection development GO:0010975 169 0.013
renal system development GO:0072001 225 0.013
positive regulation of secretion GO:0051047 130 0.013
regulation of protein kinase b signaling GO:0051896 56 0.013
cation homeostasis GO:0055080 212 0.013
antibacterial peptide production GO:0002778 2 0.013
protein oligomerization GO:0051259 67 0.013
membrane organization GO:0061024 245 0.013
purine nucleotide catabolic process GO:0006195 211 0.013
negative regulation of nervous system development GO:0051961 156 0.013
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.013
muscle system process GO:0003012 141 0.013
synaptic transmission GO:0007268 329 0.013
Human
purine nucleoside metabolic process GO:0042278 241 0.013
modification dependent protein catabolic process GO:0019941 133 0.013
regulation of lipid metabolic process GO:0019216 118 0.013
polysaccharide biosynthetic process GO:0000271 20 0.013
regulation of organelle organization GO:0033043 289 0.013
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.013
purine nucleoside triphosphate catabolic process GO:0009146 203 0.013
anion transport GO:0006820 177 0.013
mitochondrion organization GO:0007005 134 0.013
regulation of vasculature development GO:1901342 88 0.013
positive regulation of cell projection organization GO:0031346 95 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
negative regulation of gluconeogenesis GO:0045721 9 0.013
ribonucleotide catabolic process GO:0009261 208 0.013
striated muscle tissue development GO:0014706 293 0.012
kidney development GO:0001822 213 0.012
lysosome organization GO:0007040 21 0.012
divalent metal ion transport GO:0070838 172 0.012
cellular polysaccharide metabolic process GO:0044264 38 0.012
angiogenesis GO:0001525 201 0.012
mesonephros development GO:0001823 97 0.012
regulation of organ morphogenesis GO:2000027 144 0.012
purine ribonucleoside metabolic process GO:0046128 241 0.012
blood circulation GO:0008015 195 0.012
cellular protein catabolic process GO:0044257 155 0.012
vesicle organization GO:0016050 60 0.012
regionalization GO:0003002 337 0.012
cellular response to nitric oxide GO:0071732 4 0.012
response to transforming growth factor beta GO:0071559 88 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
response to acid chemical GO:0001101 111 0.012
nucleoside triphosphate catabolic process GO:0009143 205 0.012
hair cycle GO:0042633 90 0.012
mesenchyme development GO:0060485 152 0.012
organic cyclic compound catabolic process GO:1901361 295 0.012
antibacterial peptide secretion GO:0002779 1 0.012
wound healing GO:0042060 157 0.012
positive regulation of homeostatic process GO:0032846 64 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
regulation of gluconeogenesis GO:0006111 30 0.012
monosaccharide metabolic process GO:0005996 106 0.012
mesodermal cell migration GO:0008078 4 0.012
cellular response to lipopolysaccharide GO:0071222 77 0.012
circulatory system process GO:0003013 197 0.012
regulation of cytokine secretion GO:0050707 61 0.012
regulation of chondrocyte differentiation GO:0032330 33 0.012
cytokine secretion GO:0050663 72 0.012
small molecule biosynthetic process GO:0044283 132 0.012
ubiquitin dependent protein catabolic process GO:0006511 129 0.012
nucleoside metabolic process GO:0009116 246 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.012
carbohydrate derivative catabolic process GO:1901136 231 0.012
cellular homeostasis GO:0019725 240 0.011
skin development GO:0043588 220 0.011
nucleotide metabolic process GO:0009117 332 0.011
glycoprotein metabolic process GO:0009100 116 0.011
protein catabolic process GO:0030163 221 0.011
stem cell development GO:0048864 219 0.011
negative regulation of immune system process GO:0002683 209 0.011
positive regulation of cytokine secretion GO:0050715 41 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
endochondral bone morphogenesis GO:0060350 50 0.011
appendage development GO:0048736 166 0.011
female meiosis chromosome segregation GO:0016321 1 0.011
antimicrobial peptide secretion GO:0002776 1 0.011
germ cell development GO:0007281 185 0.011
positive regulation of programmed cell death GO:0043068 218 0.011
regulation of cellular component size GO:0032535 121 0.011
sequestering of calcium ion GO:0051208 18 0.011
regulation of morphogenesis of a branching structure GO:0060688 53 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.011
production of molecular mediator of immune response GO:0002440 103 0.011
glucan metabolic process GO:0044042 32 0.011
actin cytoskeleton organization GO:0030036 220 0.011
cell maturation GO:0048469 127 0.011
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.011
t cell activation GO:0042110 289 0.011
nucleotide catabolic process GO:0009166 217 0.011
oocyte construction GO:0007308 2 0.011
cardiac muscle tissue development GO:0048738 130 0.011
sensory perception GO:0007600 245 0.011
gtp metabolic process GO:0046039 144 0.011
adaptive immune response GO:0002250 155 0.011
antimicrobial peptide production GO:0002775 2 0.011
modification dependent macromolecule catabolic process GO:0043632 133 0.011
cardiac muscle cell differentiation GO:0055007 69 0.011
physiological muscle hypertrophy GO:0003298 3 0.011
regulation of ossification GO:0030278 112 0.011
organonitrogen compound catabolic process GO:1901565 264 0.011
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.011
organic anion transport GO:0015711 137 0.011
purine containing compound catabolic process GO:0072523 213 0.011
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.010
cell fate commitment GO:0045165 210 0.010
digestive system development GO:0055123 200 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.010
negative regulation of erk1 and erk2 cascade GO:0070373 21 0.010
rhythmic process GO:0048511 174 0.010
peptidyl tyrosine modification GO:0018212 145 0.010
divalent inorganic cation transport GO:0072511 178 0.010
hexose transport GO:0008645 56 0.010
intracellular protein transport GO:0006886 204 0.010
organic acid biosynthetic process GO:0016053 86 0.010
regulation of glucose import GO:0046324 26 0.010
cellular carbohydrate metabolic process GO:0044262 119 0.010
regulation of erk1 and erk2 cascade GO:0070372 71 0.010
fibroblast proliferation GO:0048144 35 0.010
protein modification by small protein conjugation or removal GO:0070647 207 0.010
purine ribonucleotide catabolic process GO:0009154 208 0.010

Srpx2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
nervous system disease DOID:863 0 0.035
sensory system disease DOID:0050155 0 0.028
musculoskeletal system disease DOID:17 0 0.025
connective tissue disease DOID:65 0 0.025
myopathy DOID:423 0 0.024
muscular disease DOID:0080000 0 0.024
muscle tissue disease DOID:66 0 0.024
retinal disease DOID:5679 0 0.022
retinal degeneration DOID:8466 0 0.022
eye and adnexa disease DOID:1492 0 0.022
eye disease DOID:5614 0 0.022
congenital muscular dystrophy DOID:0050557 0 0.012
muscular dystrophy DOID:9884 0 0.012