IMP

Process View

Mus musculus

14 genes annotated in mouse

protein heterooligomerization

The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers that are not all identical. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "protein heterooligomerization"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "protein heterooligomerization" (in gray)

Name	Description	Probability	Func Analog Organism
Col1a1	collagen, type I, alpha 1	0.979
Col6a2	collagen, type VI, alpha 2	0.740	Human
C1qc	complement component 1, q subcomponent, C chain	0.719	Mouse
C1qa	complement component 1, q subcomponent, alpha polypeptide	0.709	Mouse
C1qb	complement component 1, q subcomponent, beta polypeptide	0.602	Mouse
Col5a2	collagen, type V, alpha 2	0.556	Mouse
Col3a1	collagen, type III, alpha 1	0.527	Mouse
Hbb-b1	hemoglobin, beta adult major chain	0.442	Rat
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.339
Col1a2	collagen, type I, alpha 2	0.251
Col6a1	collagen, type VI, alpha 1	0.251	Human
Tlr4	toll-like receptor 4	0.228
Gbp5	guanylate binding protein 5	0.211
Prkab1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	0.169
Col5a1	collagen, type V, alpha 1	0.167	Mouse
Eln	elastin	0.159
Chrna3	cholinergic receptor, nicotinic, alpha polypeptide 3	0.151
Lum	lumican	0.133
Col6a3	collagen, type VI, alpha 3	0.133
Adamts2	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2	0.130
Pparg	peroxisome proliferator activated receptor gamma	0.128
Grb10	growth factor receptor bound protein 10	0.119
Prkag1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	0.118	Rat
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.114
Cav1	caveolin 1, caveolae protein	0.105
Serpinh1	serine (or cysteine) peptidase inhibitor, clade H, member 1	0.101
Nos1	nitric oxide synthase 1, neuronal	0.090
Postn	periostin, osteoblast specific factor	0.085
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.082
Pycard	PYD and CARD domain containing	0.081
Mmp2	matrix metallopeptidase 2	0.075
Nlrp3	NLR family, pyrin domain containing 3	0.075
Ank1	ankyrin 1, erythroid	0.072
Lims1	LIM and senescent cell antigen-like domains 1	0.071
Mgp	matrix Gla protein	0.070
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.070
Nf2	neurofibromatosis 2	0.063
Col4a2	collagen, type IV, alpha 2	0.061
Parva	parvin, alpha	0.061	Rat
Il18	interleukin 18	0.060
Csf1r	colony stimulating factor 1 receptor	0.059
Lyz2	lysozyme 2	0.058
Sparc	secreted acidic cysteine rich glycoprotein	0.055
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.051
Stub1	STIP1 homology and U-Box containing protein 1	0.050
Ilk	integrin linked kinase	0.050	Rat
Chrnb2	cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)	0.047
Cd44	CD44 antigen	0.046
Ikbkg	inhibitor of kappaB kinase gamma	0.046
Ctss	cathepsin S	0.045
Nrxn1	neurexin I	0.045
Dysf	dysferlin	0.044
Aim2	absent in melanoma 2	0.043
Igbp1	immunoglobulin (CD79A) binding protein 1	0.041
Prkaca	protein kinase, cAMP dependent, catalytic, alpha	0.041
Pcolce	procollagen C-endopeptidase enhancer protein	0.041
Trp53	transformation related protein 53	0.039
S100a11	S100 calcium binding protein A11 (calgizzarin)	0.039
Pml	promyelocytic leukemia	0.039
Mrc1	mannose receptor, C type 1	0.038
Tnc	tenascin C	0.038
Ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	0.038
Islr	immunoglobulin superfamily containing leucine-rich repeat	0.037
Igf2r	insulin-like growth factor 2 receptor	0.036
Ly86	lymphocyte antigen 86	0.036
Bicc1	bicaudal C homolog 1 (Drosophila)	0.035
Tyrobp	TYRO protein tyrosine kinase binding protein	0.034
Stat3	signal transducer and activator of transcription 3	0.034
H2-Aa	histocompatibility 2, class II antigen A, alpha	0.032
Col15a1	collagen, type XV, alpha 1	0.032
Mlf2	myeloid leukemia factor 2	0.032
Hba-a1	hemoglobin alpha, adult chain 1	0.031	Human Rat
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.031
Keap1	kelch-like ECH-associated protein 1	0.031
Kl	klotho	0.031
Wisp1	WNT1 inducible signaling pathway protein 1	0.030
Bgn	biglycan	0.030
Hbb-b2	hemoglobin, beta adult minor chain	0.030
Slc11a2	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2	0.030
Col8a1	collagen, type VIII, alpha 1	0.029
Lmna	lamin A	0.029
Aif1	allograft inflammatory factor 1	0.028
Col4a5	collagen, type IV, alpha 5	0.028
Srpx2	sushi-repeat-containing protein, X-linked 2	0.028
Adam12	a disintegrin and metallopeptidase domain 12 (meltrin alpha)	0.028
Fgfr2	fibroblast growth factor receptor 2	0.027
Fkbp10	FK506 binding protein 10	0.027
Ppp1ca	protein phosphatase 1, catalytic subunit, alpha isoform	0.027
Nphp4	nephronophthisis 4 (juvenile) homolog (human)	0.027
Il1r1	interleukin 1 receptor, type I	0.027
Creb3l1	cAMP responsive element binding protein 3-like 1	0.027
Rrm2	ribonucleotide reductase M2	0.027
Ctnnb1	catenin (cadherin associated protein), beta 1	0.026	Rat
Lep	leptin	0.025
Mfap4	microfibrillar-associated protein 4	0.025
Col14a1	collagen, type XIV, alpha 1	0.024
S100a10	S100 calcium binding protein A10 (calpactin)	0.024	Human
Slc12a5	solute carrier family 12, member 5	0.023
Insr	insulin receptor	0.023	Human Rat
Thbs2	thrombospondin 2	0.022
Lepr	leptin receptor	0.022
Gli3	GLI-Kruppel family member GLI3	0.022
Ceacam16	carcinoembryonic antigen-related cell adhesion molecule 16	0.022
Rrm1	ribonucleotide reductase M1	0.022
Tsc1	tuberous sclerosis 1	0.021
Ctnnd1	catenin (cadherin associated protein), delta 1	0.021
Emilin1	elastin microfibril interfacer 1	0.021
Apc	adenomatosis polyposis coli	0.021
Cd248	CD248 antigen, endosialin	0.021
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.021
Smo	smoothened homolog (Drosophila)	0.021
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.021
Ctsk	cathepsin K	0.020
Fbn1	fibrillin 1	0.020
Rfng	RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	0.020
Ulk1	Unc-51 like kinase 1 (C. elegans)	0.020
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.020
Mgea5	meningioma expressed antigen 5 (hyaluronidase)	0.020
Prkce	protein kinase C, epsilon	0.019
Fstl1	follistatin-like 1	0.019
Trim47	tripartite motif-containing 47	0.019
Ltbp2	latent transforming growth factor beta binding protein 2	0.019
Apc2	adenomatosis polyposis coli 2	0.019
Psap	prosaposin	0.019
Ms4a6d	membrane-spanning 4-domains, subfamily A, member 6D	0.019
Mfap5	microfibrillar associated protein 5	0.018
Anxa2	annexin A2	0.018	Human
Dck	deoxycytidine kinase	0.018
Plxna3	plexin A3	0.018
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.018
Igf2	insulin-like growth factor 2	0.018
Cbfb	core binding factor beta	0.018
Cd74	CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)	0.018
Igfbp7	insulin-like growth factor binding protein 7	0.018
Fgfr3	fibroblast growth factor receptor 3	0.018
Gtf2ird1	general transcription factor II I repeat domain-containing 1	0.018
B3gnt9-ps	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9, pseudogene	0.018
Itpr2	inositol 1,4,5-triphosphate receptor 2	0.017
Sik3	SIK family kinase 3	0.017
Epor	erythropoietin receptor	0.017
Pld4	phospholipase D family, member 4	0.017
Gck	glucokinase	0.017
Tmpo	thymopoietin	0.017
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.016
Ins2	insulin II	0.016
Irs2	insulin receptor substrate 2	0.016
Col16a1	collagen, type XVI, alpha 1	0.016
Ccdc80	coiled-coil domain containing 80	0.016
Spp1	secreted phosphoprotein 1	0.016
Mcm5	minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)	0.015
Tgfbi	transforming growth factor, beta induced	0.015
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.015
Dlk1	delta-like 1 homolog (Drosophila)	0.015
Kdelr3	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3	0.015
Bmp1	bone morphogenetic protein 1	0.015
Mcm4	minichromosome maintenance deficient 4 homolog (S. cerevisiae)	0.015
Raf1	v-raf-leukemia viral oncogene 1	0.015
Dpysl4	dihydropyrimidinase-like 4	0.015
Col4a1	collagen, type IV, alpha 1	0.015
Fcgr3	Fc receptor, IgG, low affinity III	0.015
Wdr1	WD repeat domain 1	0.015
Gli2	GLI-Kruppel family member GLI2	0.014
Loxl1	lysyl oxidase-like 1	0.014
Slc38a5	solute carrier family 38, member 5	0.014
Npas3	neuronal PAS domain protein 3	0.014
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.014	Rat
Mapk1	mitogen-activated protein kinase 1	0.014
P2ry6	pyrimidinergic receptor P2Y, G-protein coupled, 6	0.014
Fgfr1	fibroblast growth factor receptor 1	0.014
Stag2	stromal antigen 2	0.014
Spna1	spectrin alpha 1	0.014
Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.014	Human
Myd88	myeloid differentiation primary response gene 88	0.014
Akt1	thymoma viral proto-oncogene 1	0.014
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.014
Ythdf3	YTH domain family 3	0.014
Smad4	MAD homolog 4 (Drosophila)	0.013
Rad21	RAD21 homolog (S. pombe)	0.013
Lgals1	lectin, galactose binding, soluble 1	0.013
Mpeg1	macrophage expressed gene 1	0.013
Col11a1	collagen, type XI, alpha 1	0.013	Mouse
Trpm1	transient receptor potential cation channel, subfamily M, member 1	0.013
Khdrbs2	KH domain containing, RNA binding, signal transduction associated 2	0.013
D4Wsu53e	DNA segment, Chr 4, Wayne State University 53, expressed	0.013
Nedd4	neural precursor cell expressed, developmentally down-regulated 4	0.013
Casp8	caspase 8	0.013
4732456N10Rik	RIKEN cDNA 4732456N10 gene	0.013
Smad3	MAD homolog 3 (Drosophila)	0.013
Gpr50	G-protein-coupled receptor 50	0.013
Rpgrip1l	Rpgrip1-like	0.013
En2	engrailed 2	0.013
Ccl2	chemokine (C-C motif) ligand 2	0.013
Col9a1	collagen, type IX, alpha 1	0.013
H2-Ab1	histocompatibility 2, class II antigen A, beta 1	0.013
Gucy2e	guanylate cyclase 2e	0.012
Fam76b	family with sequence similarity 76, member B	0.012
Tia1	cytotoxic granule-associated RNA binding protein 1	0.012
Cdkn2d	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	0.012
Olfml3	olfactomedin-like 3	0.012
Ctgf	connective tissue growth factor	0.012
Ltbp3	latent transforming growth factor beta binding protein 3	0.012
H2-Eb1	histocompatibility 2, class II antigen E beta	0.012
Acan	aggrecan	0.012
Ebf3	early B-cell factor 3	0.012
Fcgr1	Fc receptor, IgG, high affinity I	0.012
Satb2	special AT-rich sequence binding protein 2	0.012
Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2	0.011
Cntn2	contactin 2	0.011
Pax1	paired box gene 1	0.011
Fbxo32	F-box protein 32	0.011
Igdcc4	immunoglobulin superfamily, DCC subclass, member 4	0.011
Crip1	cysteine-rich protein 1 (intestinal)	0.011
Ghr	growth hormone receptor	0.011
Cbln1	cerebellin 1 precursor protein	0.011	Mouse
Rpe65	retinal pigment epithelium 65	0.011
Kcnd3	potassium voltage-gated channel, Shal-related family, member 3	0.011
Spns1	spinster homolog 1 (Drosophila)	0.011
Cidea	cell death-inducing DNA fragmentation factor, alpha subunit-like effector A	0.011
Dpt	dermatopontin	0.011
Clk1	CDC-like kinase 1	0.011
Anapc1	anaphase promoting complex subunit 1	0.011
Nrk	Nik related kinase	0.010
Thbs1	thrombospondin 1	0.010
Actn3	actinin alpha 3	0.010
Clec4n	C-type lectin domain family 4, member n	0.010
Vhl	von Hippel-Lindau tumor suppressor	0.010
Svep1	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1	0.010
Hapln1	hyaluronan and proteoglycan link protein 1	0.010
Ubc	ubiquitin C	0.010
Adam19	a disintegrin and metallopeptidase domain 19 (meltrin beta)	0.010
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.010
Mmp23	matrix metallopeptidase 23	0.010
P2rx2	purinergic receptor P2X, ligand-gated ion channel, 2	0.010