Mus musculus

39 known processes

Srsf1

serine/arginine-rich splicing factor 1

(Aliases: AI482334,6330415C05Rik,Sf2,5730507C05Rik,AW491331,Sfrs1,Asf,1110054N12Rik)

Srsf1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mrna splicing via spliceosome GO:0000398 43 0.997
Human Yeast
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.996
Human Yeast
rna splicing GO:0008380 54 0.995
mrna processing GO:0006397 63 0.989
Human Yeast
mrna metabolic process GO:0016071 84 0.987
Human Yeast
regulation of mrna splicing via spliceosome GO:0048024 32 0.966
alternative mrna splicing via spliceosome GO:0000380 12 0.960
regulation of rna splicing GO:0043484 37 0.910
rna processing GO:0006396 105 0.886
rna splicing via transesterification reactions GO:0000375 43 0.877
Human Yeast
posttranscriptional gene silencing by rna GO:0035194 10 0.813
posttranscriptional regulation of gene expression GO:0010608 155 0.784
Yeast
translation GO:0006412 93 0.767
Yeast
ribonucleoprotein complex subunit organization GO:0071826 28 0.703
Human
regulation of mrna stability GO:0043488 23 0.649
mrna catabolic process GO:0006402 22 0.607
Yeast
gene silencing GO:0016458 38 0.598
rna 3 end processing GO:0031123 20 0.582
rna catabolic process GO:0006401 29 0.577
Yeast
regulation of mrna processing GO:0050684 41 0.568
regulation of transcription by chromatin organization GO:0034401 0 0.566
negative regulation of rna splicing GO:0033119 12 0.516
gene silencing by rna GO:0031047 19 0.492
germ cell development GO:0007281 185 0.489
nucleic acid transport GO:0050657 18 0.474
Yeast
regulation of alternative mrna splicing via spliceosome GO:0000381 8 0.472
regulation of rna stability GO:0043487 26 0.463
negative regulation of mrna splicing via spliceosome GO:0048025 12 0.459
regulation of protein complex disassembly GO:0043244 28 0.457
Yeast
regulation of cell cycle GO:0051726 281 0.416
Fly
organic cyclic compound catabolic process GO:1901361 295 0.389
Yeast
heterocycle catabolic process GO:0046700 280 0.371
Yeast
3 utr mediated mrna stabilization GO:0070935 2 0.361
regulation of apoptotic signaling pathway GO:2001233 197 0.322
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 1 0.293
meiotic nuclear division GO:0007126 115 0.285
mitotic cell cycle process GO:1903047 159 0.285
Fly
histone h3 deacetylation GO:0070932 8 0.283
regulation of cell cycle process GO:0010564 160 0.279
Fly
regulation of chromatin binding GO:0035561 7 0.255
regionalization GO:0003002 337 0.239
rna interference GO:0016246 2 0.236
spliceosomal complex assembly GO:0000245 6 0.230
Human
rna localization GO:0006403 23 0.218
Yeast
regulation of mrna metabolic process GO:1903311 43 0.217
meiotic cell cycle GO:0051321 122 0.197
oocyte construction GO:0007308 2 0.191
negative regulation of cellular protein metabolic process GO:0032269 247 0.191
Yeast
oogenesis GO:0048477 56 0.186
cell division GO:0051301 120 0.185
apoptotic signaling pathway GO:0097190 306 0.179
negative regulation of cellular component organization GO:0051129 194 0.178
Yeast
regulation of translation GO:0006417 71 0.177
Yeast
cytoplasmic transport GO:0016482 234 0.168
Yeast
oocyte anterior posterior axis specification GO:0007314 2 0.161
dna templated transcription termination GO:0006353 4 0.158
Yeast
multicellular organism growth GO:0035264 161 0.156
oocyte axis specification GO:0007309 2 0.151
rna stabilization GO:0043489 9 0.151
negative regulation of mrna processing GO:0050686 12 0.141
macromolecular complex disassembly GO:0032984 43 0.133
Yeast
intrinsic apoptotic signaling pathway GO:0097193 132 0.124
generation of precursor metabolites and energy GO:0006091 103 0.122
nuclear division GO:0000280 158 0.122
female gamete generation GO:0007292 74 0.121
regulation of organelle organization GO:0033043 289 0.112
mitotic cell cycle GO:0000278 195 0.109
Fly
organelle fission GO:0048285 170 0.109
oxidation reduction process GO:0055114 342 0.106
mrna export from nucleus GO:0006406 11 0.101
Yeast
negative regulation of mrna metabolic process GO:1903312 13 0.099
aromatic compound catabolic process GO:0019439 286 0.097
Yeast
posttranscriptional gene silencing GO:0016441 10 0.096
nitrogen compound transport GO:0071705 271 0.095
Yeast
germ cell proliferation GO:0036093 7 0.091
histone modification GO:0016570 159 0.089
macromolecule catabolic process GO:0009057 281 0.088
Yeast
cellular nitrogen compound catabolic process GO:0044270 280 0.086
Yeast
ossification GO:0001503 216 0.085
nucleus organization GO:0006997 45 0.081
nuclear transcribed mrna catabolic process GO:0000956 16 0.080
Yeast
establishment of organelle localization GO:0051656 122 0.080
negative regulation of molecular function GO:0044092 258 0.080
chromatin modification GO:0016568 187 0.077
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.077
regulation of cell cycle phase transition GO:1901987 77 0.075
Fly
establishment of rna localization GO:0051236 18 0.074
Yeast
mrna stabilization GO:0048255 9 0.073
circadian rhythm GO:0007623 114 0.071
maternal determination of anterior posterior axis embryo GO:0008358 2 0.071
endocytosis GO:0006897 168 0.070
Worm
cellular macromolecule catabolic process GO:0044265 206 0.068
Yeast
negative regulation of protein metabolic process GO:0051248 282 0.067
Yeast
positive regulation of mrna metabolic process GO:1903313 17 0.067
chromatin organization GO:0006325 206 0.065
mitotic nuclear division GO:0007067 48 0.061
male gamete generation GO:0048232 285 0.059
oocyte development GO:0048599 33 0.058
mrna localization resulting in posttranscriptional regulation of gene expression GO:0010609 2 0.057
spermatid differentiation GO:0048515 115 0.057
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.055
nucleobase containing compound transport GO:0015931 27 0.055
Yeast
mrna splice site selection GO:0006376 5 0.054
Human
viral process GO:0016032 41 0.054
organelle assembly GO:0070925 177 0.054
protein methylation GO:0006479 81 0.052
adult locomotory behavior GO:0008344 91 0.052
negative regulation of synapse assembly GO:0051964 3 0.050
positive regulation of intracellular estrogen receptor signaling pathway GO:0033148 4 0.048
skin development GO:0043588 220 0.047
microtubule cytoskeleton organization GO:0000226 157 0.046
epidermal cell division GO:0010481 3 0.045
intracellular protein transport GO:0006886 204 0.045
energy derivation by oxidation of organic compounds GO:0015980 77 0.044
neuron projection extension GO:1990138 64 0.044
negative regulation of translation GO:0017148 22 0.043
Yeast
nucleocytoplasmic transport GO:0006913 139 0.042
Yeast
ras protein signal transduction GO:0007265 77 0.042
organelle localization GO:0051640 179 0.042
spermatid development GO:0007286 108 0.042
regulation of circadian rhythm GO:0042752 58 0.042
ribonucleoprotein complex disassembly GO:0032988 3 0.041
heterochromatin organization GO:0070828 4 0.040
response to heat GO:0009408 27 0.039
heterochromatin assembly GO:0031507 2 0.039
nucleobase containing small molecule metabolic process GO:0055086 352 0.038
developmental growth involved in morphogenesis GO:0060560 138 0.038
negative regulation of cell cycle phase transition GO:1901988 48 0.038
Fly
rna transport GO:0050658 18 0.037
Yeast
macromolecule methylation GO:0043414 120 0.034
mrna 3 end processing GO:0031124 16 0.033
cellular response to oxidative stress GO:0034599 76 0.033
positive regulation of glycogen catabolic process GO:0045819 2 0.033
protein complex disassembly GO:0043241 40 0.032
Yeast
developmental maturation GO:0021700 193 0.031
negative regulation of cell cycle GO:0045786 123 0.031
Fly
developmental cell growth GO:0048588 84 0.031
spermatogenesis GO:0007283 284 0.031
cellular polysaccharide catabolic process GO:0044247 5 0.030
regulation of cellular response to stress GO:0080135 159 0.029
body morphogenesis GO:0010171 45 0.029
interspecies interaction between organisms GO:0044419 83 0.029
gonad development GO:0008406 141 0.029
Worm
nuclear transport GO:0051169 139 0.029
Yeast
regulation of multi organism process GO:0043900 111 0.028
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.028
sensory perception GO:0007600 245 0.028
receptor biosynthetic process GO:0032800 3 0.028
organonitrogen compound biosynthetic process GO:1901566 192 0.027
positive regulation of cell cycle process GO:0090068 61 0.027
response to oxidative stress GO:0006979 123 0.027
positive regulation of programmed cell death GO:0043068 218 0.027
glucan metabolic process GO:0044042 32 0.026
nucleotide catabolic process GO:0009166 217 0.026
pallium development GO:0021543 120 0.026
regulation of nuclear division GO:0051783 56 0.026
regulation of meiotic cell cycle GO:0051445 34 0.026
female sex determination GO:0030237 1 0.026
regulation of cytoskeleton organization GO:0051493 122 0.025
cellular protein complex assembly GO:0043623 116 0.025
rrna containing ribonucleoprotein complex export from nucleus GO:0071428 1 0.025
intracellular mrna localization GO:0008298 4 0.025
morphogenesis of embryonic epithelium GO:0016331 159 0.025
regulation of cellular response to hypoxia GO:1900037 2 0.025
glycogen catabolic process GO:0005980 5 0.024
maternal placenta development GO:0001893 20 0.024
cellular glucan metabolic process GO:0006073 32 0.024
protein localization to membrane GO:0072657 108 0.024
segmentation GO:0035282 93 0.024
adult behavior GO:0030534 135 0.024
regulation of neuron projection development GO:0010975 169 0.023
myosin filament organization GO:0031033 3 0.023
negative regulation of nervous system development GO:0051961 156 0.023
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 19 0.023
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.023
cellular response to dna damage stimulus GO:0006974 207 0.023
Fly
positive regulation of rna splicing GO:0033120 12 0.023
mrna transport GO:0051028 13 0.023
Yeast
pole plasm assembly GO:0007315 2 0.022
peptidyl lysine trimethylation GO:0018023 12 0.022
purine containing compound biosynthetic process GO:0072522 70 0.022
regulation of cell division GO:0051302 76 0.022
nucleoside phosphate catabolic process GO:1901292 222 0.022
determination of adult lifespan GO:0008340 11 0.022
regulation of chromosome organization GO:0033044 83 0.022
fertilization GO:0009566 127 0.021
modification by host of symbiont morphology or physiology GO:0051851 12 0.021
regulation of mitotic cell cycle phase transition GO:1901990 73 0.021
Fly
cellular polysaccharide metabolic process GO:0044264 38 0.021
negative regulation of multi organism process GO:0043901 68 0.020
single fertilization GO:0007338 82 0.020
myeloid cell differentiation GO:0030099 233 0.020
purine nucleoside metabolic process GO:0042278 241 0.020
snorna metabolic process GO:0016074 1 0.020
inflammatory response GO:0006954 244 0.020
epithelial cell proliferation GO:0050673 174 0.020
regulation of cellular component biogenesis GO:0044087 181 0.019
engulfment of apoptotic cell GO:0043652 3 0.019
visual perception GO:0007601 52 0.019
positive regulation of cell death GO:0010942 224 0.019
stem cell development GO:0048864 219 0.019
multi multicellular organism process GO:0044706 109 0.019
maintenance of location GO:0051235 89 0.019
axonogenesis GO:0007409 274 0.018
response to lipopolysaccharide GO:0032496 128 0.018
regulation of ras protein signal transduction GO:0046578 114 0.018
negative regulation of neuron projection regeneration GO:0070571 3 0.018
regulation of mitotic cell cycle GO:0007346 126 0.018
Fly
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.018
response to molecule of bacterial origin GO:0002237 143 0.018
amp metabolic process GO:0046033 4 0.018
regulation of kinase activity GO:0043549 249 0.018
mitotic spindle organization GO:0007052 10 0.018
epidermis development GO:0008544 187 0.018
cellular amino acid metabolic process GO:0006520 103 0.017
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 16 0.017
cell maturation GO:0048469 127 0.017
negative regulation of protein complex disassembly GO:0043242 22 0.017
Yeast
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
small gtpase mediated signal transduction GO:0007264 97 0.016
nls bearing protein import into nucleus GO:0006607 2 0.016
protein localization to nucleus GO:0034504 121 0.016
development of primary sexual characteristics GO:0045137 143 0.016
Worm
ribonucleotide metabolic process GO:0009259 291 0.016
compound eye development GO:0048749 1 0.016
methylation GO:0032259 134 0.016
ribose phosphate metabolic process GO:0019693 291 0.016
chemotaxis GO:0006935 247 0.016
regulation of dna templated transcription termination GO:0031554 1 0.016
Yeast
cellular amine metabolic process GO:0044106 44 0.015
regulation of microtubule based process GO:0032886 52 0.015
digestive tract morphogenesis GO:0048546 147 0.015
negative regulation of cell projection organization GO:0031345 56 0.015
maternal process involved in female pregnancy GO:0060135 32 0.015
cell cycle g1 s phase transition GO:0044843 57 0.015
purine nucleotide catabolic process GO:0006195 211 0.015
negative regulation of cell division GO:0051782 24 0.015
positive regulation of mrna splicing via spliceosome GO:0048026 11 0.015
forebrain development GO:0030900 302 0.014
response to organic cyclic compound GO:0014070 198 0.014
rna dependent dna replication GO:0006278 3 0.014
hippocampus development GO:0021766 52 0.014
centriole assembly GO:0098534 6 0.014
respiratory system development GO:0060541 190 0.014
positive regulation of apoptotic process GO:0043065 217 0.014
negative regulation of protein modification process GO:0031400 163 0.014
mitotic cell cycle checkpoint GO:0007093 31 0.014
Fly
glycogen metabolic process GO:0005977 32 0.014
nucleus localization GO:0051647 20 0.014
genitalia development GO:0048806 37 0.014
Worm
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.014
kinetochore organization GO:0051383 2 0.014
purine containing compound metabolic process GO:0072521 311 0.014
muscle cell differentiation GO:0042692 261 0.013
regulation of intracellular protein transport GO:0033157 82 0.013
meiotic cell cycle process GO:1903046 77 0.013
nucleoside phosphate biosynthetic process GO:1901293 79 0.013
nucleoside monophosphate metabolic process GO:0009123 85 0.013
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.013
energy reserve metabolic process GO:0006112 39 0.013
ncrna 3 end processing GO:0043628 2 0.013
dendrite development GO:0016358 115 0.013
response to temperature stimulus GO:0009266 55 0.013
regulation of cellular response to oxidative stress GO:1900407 19 0.013
amine metabolic process GO:0009308 45 0.012
protein targeting GO:0006605 143 0.012
negative regulation of neuron projection development GO:0010977 50 0.012
positive regulation of translation GO:0045727 19 0.012
female sex differentiation GO:0046660 84 0.012
fungiform papilla morphogenesis GO:0061197 5 0.012
protein dna complex subunit organization GO:0071824 28 0.012
metaphase plate congression GO:0051310 2 0.012
cytokine metabolic process GO:0042107 71 0.012
termination of rna polymerase ii transcription GO:0006369 1 0.012
Yeast
gene silencing by mirna GO:0035195 10 0.012
amp biosynthetic process GO:0006167 2 0.012
carbohydrate derivative catabolic process GO:1901136 231 0.012
protein localization to organelle GO:0033365 185 0.011
positive regulation of growth GO:0045927 104 0.011
anatomical structure homeostasis GO:0060249 145 0.011
multicellular organismal aging GO:0010259 24 0.011
regulation of cytokine production GO:0001817 266 0.011
dephosphorylation GO:0016311 129 0.011
rhythmic process GO:0048511 174 0.011
regulation of cellular amino acid metabolic process GO:0006521 5 0.011
positive regulation of mrna processing GO:0050685 16 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.011
actin cytoskeleton organization GO:0030036 220 0.011
positive regulation of apoptotic signaling pathway GO:2001235 95 0.010
positive regulation of nervous system development GO:0051962 221 0.010
positive regulation of proteolysis GO:0045862 85 0.010
centromere complex assembly GO:0034508 3 0.010
positive regulation of cell cycle GO:0045787 92 0.010
nucleoside catabolic process GO:0009164 206 0.010
regulation of microtubule cytoskeleton organization GO:0070507 37 0.010
regulation of epithelial cell proliferation GO:0050678 141 0.010
wax biosynthetic process GO:0010025 2 0.010
membrane organization GO:0061024 245 0.010
regulation of neuron differentiation GO:0045664 281 0.010
negative regulation of apoptotic cell clearance GO:2000426 1 0.010

Srsf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.095
disease of anatomical entity DOID:7 0 0.095
nervous system disease DOID:863 0 0.095
neurodegenerative disease DOID:1289 0 0.043
motor neuron disease DOID:231 0 0.032