|
|
renin angiotensin regulation of aldosterone production
|
GO:0002018 |
3 |
1.000
|
|
|
|
regulation of renal output by angiotensin
|
GO:0002019 |
2 |
1.000
|
|
|
|
phospholipase c activating angiotensin activated signaling pathway
|
GO:0086097 |
1 |
1.000
|
|
|
|
regulation of systemic arterial blood pressure by circulatory renin angiotensin
|
GO:0001991 |
13 |
0.998
|
|
|
|
regulation of neurotrophin trk receptor signaling pathway
|
GO:0051386 |
4 |
0.997
|
|
|
|
angiotensin activated signaling pathway
|
GO:0038166 |
4 |
0.996
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
93 |
0.994
|
|
|
|
negative regulation of neurotrophin trk receptor signaling pathway
|
GO:0051387 |
2 |
0.994
|
|
|
|
intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator
|
GO:1990127 |
1 |
0.993
|
Mouse |
|
|
renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure
|
GO:0003072 |
5 |
0.990
|
Mouse |
|
|
cholesterol esterification
|
GO:0034435 |
3 |
0.990
|
Human |
|
|
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator
|
GO:1902239 |
1 |
0.989
|
Mouse |
|
|
negative regulation of smooth muscle cell apoptotic process
|
GO:0034392 |
1 |
0.986
|
|
|
|
regulation of angiotensin metabolic process
|
GO:0060177 |
4 |
0.974
|
|
|
|
regulation of systemic arterial blood pressure by hormone
|
GO:0001990 |
25 |
0.970
|
|
|
|
activation of janus kinase activity
|
GO:0042976 |
2 |
0.966
|
Rat |
|
|
regulation of intrinsic apoptotic signaling pathway in response to osmotic stress
|
GO:1902218 |
1 |
0.961
|
Mouse |
|
|
regulation of activation of jak2 kinase activity
|
GO:0010534 |
1 |
0.950
|
|
|
|
regulation of cholesterol esterification
|
GO:0010872 |
2 |
0.948
|
Human |
|
|
regulation of systemic arterial blood pressure by renin angiotensin
|
GO:0003081 |
20 |
0.935
|
|
|
|
norepinephrine transport
|
GO:0015874 |
2 |
0.934
|
|
|
|
positive regulation of cholesterol esterification
|
GO:0010873 |
1 |
0.933
|
Human |
|
|
cell growth involved in cardiac muscle cell development
|
GO:0061049 |
3 |
0.906
|
|
|
|
positive regulation of protein kinase c activity
|
GO:1900020 |
1 |
0.888
|
|
|
|
regulation of blood vessel size by renin angiotensin
|
GO:0002034 |
5 |
0.886
|
Mouse |
|
|
ureteric bud morphogenesis
|
GO:0060675 |
62 |
0.871
|
Mouse Rat |
|
|
negative regulation of heart rate
|
GO:0010459 |
4 |
0.867
|
Mouse |
|
|
physiological cardiac muscle hypertrophy
|
GO:0003301 |
3 |
0.861
|
|
|
|
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress
|
GO:1902219 |
1 |
0.846
|
Mouse |
|
|
regulation of cholesterol metabolic process
|
GO:0090181 |
14 |
0.845
|
|
|
|
g protein coupled receptor signaling pathway coupled to cgmp nucleotide second messenger
|
GO:0007199 |
1 |
0.842
|
Mouse |
|
|
establishment of blood nerve barrier
|
GO:0008065 |
3 |
0.840
|
|
|
|
regulation of protein kinase c activity
|
GO:1900019 |
1 |
0.830
|
|
|
|
regulation of systemic arterial blood pressure mediated by a chemical signal
|
GO:0003044 |
33 |
0.823
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.816
|
Mouse Rat |
|
|
mesonephric tubule development
|
GO:0072164 |
94 |
0.811
|
Mouse Rat |
|
|
regulation of systemic arterial blood pressure
|
GO:0003073 |
61 |
0.805
|
|
|
|
ureteric bud development
|
GO:0001657 |
94 |
0.804
|
Mouse Rat |
|
|
regulation of branching involved in ureteric bud morphogenesis
|
GO:0090189 |
22 |
0.798
|
Mouse Rat |
|
|
positive regulation of mesonephros development
|
GO:0061213 |
20 |
0.796
|
Mouse Rat |
|
|
blood circulation
|
GO:0008015 |
195 |
0.781
|
|
|
|
renal system process involved in regulation of systemic arterial blood pressure
|
GO:0003071 |
15 |
0.769
|
|
|
|
mesonephric tubule morphogenesis
|
GO:0072171 |
63 |
0.762
|
Mouse Rat |
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.756
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
21 |
0.752
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.746
|
Mouse |
|
|
nephron epithelium morphogenesis
|
GO:0072088 |
68 |
0.744
|
Mouse Rat |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.738
|
|
|
|
positive regulation of insulin receptor signaling pathway
|
GO:0046628 |
4 |
0.736
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.735
|
|
|
|
ovarian follicle rupture
|
GO:0001543 |
2 |
0.719
|
|
|
|
superoxide metabolic process
|
GO:0006801 |
27 |
0.718
|
Rat |
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.711
|
|
|
|
renal tubule development
|
GO:0061326 |
87 |
0.708
|
Mouse Rat |
|
|
feeding behavior
|
GO:0007631 |
62 |
0.706
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.705
|
Mouse Rat |
|
|
regulation of blood volume by renin angiotensin
|
GO:0002016 |
7 |
0.698
|
|
|
|
nephron tubule morphogenesis
|
GO:0072078 |
68 |
0.693
|
Mouse Rat |
|
|
positive regulation of blood pressure
|
GO:0045777 |
21 |
0.692
|
|
|
|
response to alcohol
|
GO:0097305 |
48 |
0.689
|
Rat |
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.669
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.669
|
Mouse |
|
|
metanephric glomerular mesangium development
|
GO:0072223 |
3 |
0.668
|
|
|
|
drinking behavior
|
GO:0042756 |
5 |
0.663
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.658
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.644
|
|
|
|
regulation of angiotensin levels in blood
|
GO:0002002 |
4 |
0.636
|
|
|
|
negative regulation of peptidyl serine phosphorylation
|
GO:0033137 |
10 |
0.619
|
Mouse |
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.603
|
|
|
|
positive regulation of metanephric glomerulus development
|
GO:0072300 |
4 |
0.597
|
Mouse |
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.589
|
Human Mouse |
|
|
regulation of removal of superoxide radicals
|
GO:2000121 |
4 |
0.575
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.573
|
Rat |
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.567
|
|
|
|
activation of nf kappab inducing kinase activity
|
GO:0007250 |
4 |
0.559
|
|
|
|
regulation of activation of janus kinase activity
|
GO:0010533 |
1 |
0.555
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.552
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.550
|
|
|
|
glucocorticoid biosynthetic process
|
GO:0006704 |
5 |
0.549
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.548
|
|
|
|
positive regulation of nitric oxide synthase activity
|
GO:0051000 |
2 |
0.545
|
Mouse |
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.540
|
Human Mouse Rat |
|
|
renal sodium excretion
|
GO:0035812 |
3 |
0.540
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.538
|
|
|
|
response to vitamin d
|
GO:0033280 |
3 |
0.538
|
|
|
|
negative regulation of systemic arterial blood pressure
|
GO:0003085 |
15 |
0.528
|
Mouse |
|
|
positive regulation of renal sodium excretion
|
GO:0035815 |
2 |
0.523
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.519
|
|
|
|
sterol esterification
|
GO:0034434 |
3 |
0.513
|
Human |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.509
|
Human |
|
|
regulation of norepinephrine secretion
|
GO:0014061 |
2 |
0.507
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.507
|
Mouse |
|
|
intrinsic apoptotic signaling pathway in response to osmotic stress
|
GO:0008627 |
2 |
0.506
|
Mouse |
|
|
positive regulation of branching involved in ureteric bud morphogenesis
|
GO:0090190 |
18 |
0.502
|
Mouse Rat |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.501
|
Mouse |
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.491
|
Mouse Rat |
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.488
|
|
|
|
vasodilation by angiotensin involved in regulation of systemic arterial blood pressure
|
GO:0002033 |
2 |
0.477
|
Mouse |
|
|
elastic fiber assembly
|
GO:0048251 |
4 |
0.476
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.474
|
|
|
|
ovulation from ovarian follicle
|
GO:0001542 |
9 |
0.469
|
|
|
|
hormone metabolic process
|
GO:0042445 |
86 |
0.467
|
|
|
|
steroid metabolic process
|
GO:0008202 |
119 |
0.462
|
Human |
|
|
ovulation
|
GO:0030728 |
15 |
0.461
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.450
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.444
|
Mouse |
|
|
organ regeneration
|
GO:0031100 |
2 |
0.440
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.436
|
|
|
|
peptide hormone processing
|
GO:0016486 |
9 |
0.433
|
|
|
|
regulation of lipase activity
|
GO:0060191 |
15 |
0.423
|
Human |
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.421
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.419
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.415
|
|
|
|
regulation of adrenergic receptor signaling pathway
|
GO:0071877 |
4 |
0.412
|
|
|
|
regulation of muscle adaptation
|
GO:0043502 |
31 |
0.409
|
|
|
|
regulation of superoxide anion generation
|
GO:0032928 |
4 |
0.408
|
Rat |
|
|
small molecule catabolic process
|
GO:0044282 |
71 |
0.407
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.407
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.405
|
Rat |
|
|
response to growth factor
|
GO:0070848 |
198 |
0.400
|
|
|
|
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure
|
GO:0001999 |
6 |
0.398
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.398
|
|
|
|
steroid esterification
|
GO:0034433 |
3 |
0.397
|
Human |
|
|
cellular response to glucocorticoid stimulus
|
GO:0071385 |
13 |
0.393
|
Rat |
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
51 |
0.392
|
Mouse |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.392
|
|
|
|
regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator
|
GO:1902238 |
1 |
0.391
|
Mouse |
|
|
glomerulus development
|
GO:0032835 |
40 |
0.382
|
Mouse |
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.379
|
Mouse |
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.377
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.368
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.366
|
|
|
|
physiological muscle hypertrophy
|
GO:0003298 |
3 |
0.360
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.358
|
|
|
|
renal system process
|
GO:0003014 |
48 |
0.356
|
|
|
|
regulation of gluconeogenesis
|
GO:0006111 |
30 |
0.356
|
|
|
|
drug catabolic process
|
GO:0042737 |
2 |
0.353
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
35 |
0.352
|
Mouse |
|
|
cellular sodium ion homeostasis
|
GO:0006883 |
1 |
0.351
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.350
|
|
|
|
macromolecule glycosylation
|
GO:0043413 |
55 |
0.349
|
|
|
|
negative regulation of blood pressure
|
GO:0045776 |
22 |
0.347
|
Mouse |
|
|
neurotrophin trk receptor signaling pathway
|
GO:0048011 |
8 |
0.347
|
|
|
|
mesonephric epithelium development
|
GO:0072163 |
94 |
0.346
|
Mouse Rat |
|
|
regulation of metanephric glomerulus development
|
GO:0072298 |
5 |
0.345
|
Mouse |
|
|
regulation of heart contraction
|
GO:0008016 |
77 |
0.343
|
Mouse |
|
|
response to peptide
|
GO:1901652 |
136 |
0.336
|
|
|
|
development of primary female sexual characteristics
|
GO:0046545 |
73 |
0.333
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.332
|
|
|
|
sterol metabolic process
|
GO:0016125 |
58 |
0.329
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
39 |
0.326
|
Mouse |
|
|
muscle adaptation
|
GO:0043500 |
39 |
0.325
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.322
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.319
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.319
|
|
|
|
regulation of morphogenesis of a branching structure
|
GO:0060688 |
53 |
0.315
|
Mouse Rat |
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.314
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.313
|
|
|
|
tonic smooth muscle contraction
|
GO:0014820 |
3 |
0.313
|
|
|
|
drug metabolic process
|
GO:0017144 |
4 |
0.312
|
|
|
|
mesonephros development
|
GO:0001823 |
97 |
0.311
|
Mouse Rat |
|
|
endocrine process
|
GO:0050886 |
39 |
0.311
|
|
|
|
astrocyte activation
|
GO:0048143 |
2 |
0.310
|
|
|
|
regulation of renal sodium excretion
|
GO:0035813 |
3 |
0.306
|
|
|
|
positive regulation of fatty acid biosynthetic process
|
GO:0045723 |
3 |
0.306
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.302
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.300
|
|
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
74 |
0.299
|
|
|
|
catecholamine secretion
|
GO:0050432 |
15 |
0.298
|
|
|
|
superoxide anion generation
|
GO:0042554 |
11 |
0.297
|
Rat |
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.296
|
|
|
|
metanephric glomerulus development
|
GO:0072224 |
13 |
0.296
|
Mouse |
|
|
exogenous drug catabolic process
|
GO:0042738 |
1 |
0.294
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.293
|
Rat |
|
|
response to hypoxia
|
GO:0001666 |
58 |
0.290
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.287
|
|
|
|
positive regulation of monooxygenase activity
|
GO:0032770 |
2 |
0.287
|
Mouse |
|
|
kidney epithelium development
|
GO:0072073 |
121 |
0.286
|
Mouse Rat |
|
|
fat soluble vitamin biosynthetic process
|
GO:0042362 |
4 |
0.286
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.285
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.284
|
|
|
|
ovulation cycle
|
GO:0042698 |
59 |
0.284
|
|
|
|
response to osmotic stress
|
GO:0006970 |
21 |
0.280
|
Mouse |
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
34 |
0.278
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.277
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.276
|
Human Mouse Rat |
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.272
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
62 |
0.271
|
Human Mouse Rat |
|
|
monosaccharide biosynthetic process
|
GO:0046364 |
44 |
0.266
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.265
|
Rat |
|
|
hexose metabolic process
|
GO:0019318 |
98 |
0.263
|
|
|
|
angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure
|
GO:0001998 |
3 |
0.262
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.262
|
|
|
|
nephron epithelium development
|
GO:0072009 |
92 |
0.255
|
Mouse Rat |
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.251
|
|
|
|
vasodilation
|
GO:0042311 |
28 |
0.250
|
Mouse |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.250
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.250
|
|
|
|
regulation of tube size
|
GO:0035150 |
57 |
0.249
|
Human Mouse Rat |
|
|
regulation of phosphatidylcholine catabolic process
|
GO:0010899 |
2 |
0.242
|
|
|
|
gluconeogenesis
|
GO:0006094 |
39 |
0.240
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.238
|
Human Mouse Rat |
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.238
|
|
|
|
cellular response to oxygen radical
|
GO:0071450 |
14 |
0.237
|
|
|
|
cholesterol metabolic process
|
GO:0008203 |
56 |
0.237
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.234
|
Mouse |
|
|
heart contraction
|
GO:0060047 |
93 |
0.234
|
Mouse |
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.232
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.231
|
|
|
|
fatty acid biosynthetic process
|
GO:0006633 |
41 |
0.230
|
|
|
|
cellular response to steroid hormone stimulus
|
GO:0071383 |
33 |
0.226
|
Rat |
|
|
glucocorticoid metabolic process
|
GO:0008211 |
9 |
0.225
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.225
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.222
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.218
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.218
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.218
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
65 |
0.216
|
|
|
|
female sex differentiation
|
GO:0046660 |
84 |
0.212
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.210
|
Human Mouse Rat |
|
|
nephron development
|
GO:0072006 |
109 |
0.207
|
Mouse Rat |
|
|
sodium ion homeostasis
|
GO:0055078 |
7 |
0.201
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.201
|
Mouse |
|
|
regulation of catecholamine secretion
|
GO:0050433 |
12 |
0.199
|
|
|
|
fat soluble vitamin catabolic process
|
GO:0042363 |
1 |
0.199
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.199
|
|
|
|
regulation of fatty acid biosynthetic process
|
GO:0042304 |
12 |
0.199
|
|
|
|
protein n linked glycosylation
|
GO:0006487 |
12 |
0.197
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.196
|
|
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
30 |
0.195
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.195
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.194
|
|
|
|
positive regulation of systemic arterial blood pressure
|
GO:0003084 |
9 |
0.193
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.190
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.189
|
Mouse |
|
|
positive regulation of creb transcription factor activity
|
GO:0032793 |
4 |
0.188
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.185
|
|
|
|
nephron morphogenesis
|
GO:0072028 |
69 |
0.185
|
Mouse Rat |
|
|
positive regulation of steroid metabolic process
|
GO:0045940 |
5 |
0.183
|
Human |
|
|
cardiac muscle cell differentiation
|
GO:0055007 |
69 |
0.182
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.182
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.181
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.180
|
Human Mouse Rat |
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
40 |
0.180
|
Human |
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.180
|
|
|
|
regulation of triglyceride metabolic process
|
GO:0090207 |
17 |
0.180
|
|
|
|
regulation of organ growth
|
GO:0046620 |
61 |
0.178
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.177
|
|
|
|
neurotrophin signaling pathway
|
GO:0038179 |
12 |
0.171
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.169
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.169
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.168
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.167
|
Rat |
|
|
positive regulation of phospholipase c activity
|
GO:0010863 |
2 |
0.167
|
|
|
|
protein glycosylation
|
GO:0006486 |
55 |
0.166
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
58 |
0.165
|
|
|
|
regulation of steroid metabolic process
|
GO:0019218 |
39 |
0.164
|
Human |
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.162
|
Mouse Rat |
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.162
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.162
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.160
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.160
|
|
|
|
regulation of fatty acid metabolic process
|
GO:0019217 |
28 |
0.160
|
|
|
|
regulation of superoxide metabolic process
|
GO:0090322 |
8 |
0.158
|
Rat |
|
|
acylglycerol metabolic process
|
GO:0006639 |
55 |
0.157
|
|
|
|
cholesterol homeostasis
|
GO:0042632 |
44 |
0.155
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.155
|
|
|
|
excretion
|
GO:0007588 |
22 |
0.155
|
|
|
|
lipid catabolic process
|
GO:0016042 |
69 |
0.154
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.153
|
|
|
|
response to oxygen radical
|
GO:0000305 |
16 |
0.153
|
|
|
|
plasma lipoprotein particle clearance
|
GO:0034381 |
13 |
0.152
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.152
|
|
|
|
positive regulation of lipid biosynthetic process
|
GO:0046889 |
18 |
0.151
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.151
|
|
|
|
regulation of serotonin uptake
|
GO:0051611 |
2 |
0.150
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.149
|
|
|
|
regulation of metanephros development
|
GO:0072215 |
15 |
0.148
|
Mouse |
|
|
camera type eye development
|
GO:0043010 |
266 |
0.148
|
|
|
|
female gonad development
|
GO:0008585 |
71 |
0.147
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.147
|
Mouse |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.146
|
|
|
|
striated muscle hypertrophy
|
GO:0014897 |
24 |
0.144
|
|
|
|
cellular response to catecholamine stimulus
|
GO:0071870 |
3 |
0.143
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.139
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.138
|
Human Mouse Rat |
|
|
positive regulation of vasodilation
|
GO:0045909 |
3 |
0.138
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
49 |
0.137
|
|
|
|
regulation of circadian sleep wake cycle sleep
|
GO:0045187 |
3 |
0.136
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.136
|
Mouse |
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.135
|
Rat |
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.135
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.135
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.132
|
|
|
|
regulation of glomerulus development
|
GO:0090192 |
6 |
0.132
|
Mouse |
|
|
nucleoside biosynthetic process
|
GO:0009163 |
21 |
0.132
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.132
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.129
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.128
|
|
|
|
antigen processing and presentation of exogenous antigen
|
GO:0019884 |
26 |
0.127
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.126
|
|
|
|
pigment cell differentiation
|
GO:0050931 |
27 |
0.125
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.125
|
Mouse |
|
|
nucleotide biosynthetic process
|
GO:0009165 |
78 |
0.124
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.124
|
Human |
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.124
|
Mouse |
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
70 |
0.122
|
|
|
|
triglyceride metabolic process
|
GO:0006641 |
51 |
0.121
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.121
|
Human Mouse Rat |
|
|
lipoprotein catabolic process
|
GO:0042159 |
7 |
0.121
|
|
|
|
kidney morphogenesis
|
GO:0060993 |
83 |
0.120
|
Mouse Rat |
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.119
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.118
|
Mouse |
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.118
|
Rat |
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.118
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.116
|
|
|
|
sterol homeostasis
|
GO:0055092 |
45 |
0.116
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.115
|
|
|
|
regulation of intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:1902253 |
13 |
0.115
|
Mouse |
|
|
alcohol metabolic process
|
GO:0006066 |
116 |
0.115
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.114
|
|
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
46 |
0.114
|
|
|
|
hexose biosynthetic process
|
GO:0019319 |
39 |
0.113
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.113
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.113
|
|
|
|
muscle cell apoptotic process
|
GO:0010657 |
18 |
0.111
|
|
|
|
glucose metabolic process
|
GO:0006006 |
92 |
0.111
|
|
|
|
positive regulation of extracellular matrix organization
|
GO:1903055 |
4 |
0.111
|
|
|
|
nitric oxide biosynthetic process
|
GO:0006809 |
25 |
0.110
|
|
|
|
regulation of mesonephros development
|
GO:0061217 |
24 |
0.110
|
Mouse Rat |
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.107
|
|
|
|
vitamin d catabolic process
|
GO:0042369 |
1 |
0.106
|
|
|
|
progesterone metabolic process
|
GO:0042448 |
4 |
0.106
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.106
|
|
|
|
renal tubule morphogenesis
|
GO:0061333 |
72 |
0.106
|
Mouse Rat |
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.105
|
Human |
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.105
|
|
|
|
negative regulation of blood vessel endothelial cell migration
|
GO:0043537 |
3 |
0.104
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.104
|
|
|
|
regulation of carbohydrate biosynthetic process
|
GO:0043255 |
40 |
0.102
|
|
|
|
positive regulation of bone remodeling
|
GO:0046852 |
13 |
0.102
|
|
|
|
steroid catabolic process
|
GO:0006706 |
7 |
0.101
|
|
|
|
positive regulation of adrenergic receptor signaling pathway
|
GO:0071879 |
3 |
0.101
|
|
|
|
nik nf kappab signaling
|
GO:0038061 |
14 |
0.101
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
40 |
0.101
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.100
|
Mouse |
|
|
carboxylic acid catabolic process
|
GO:0046395 |
51 |
0.100
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.098
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.097
|
|
|
|
male sex differentiation
|
GO:0046661 |
109 |
0.097
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.097
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.095
|
|
|
|
endothelial cell differentiation
|
GO:0045446 |
41 |
0.094
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.094
|
Mouse Rat |
|
|
alcohol catabolic process
|
GO:0046164 |
16 |
0.094
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.094
|
|
|
|
activation of phospholipase c activity
|
GO:0007202 |
2 |
0.093
|
|
|
|
organic hydroxy compound catabolic process
|
GO:1901616 |
25 |
0.093
|
|
|
|
membrane protein proteolysis
|
GO:0033619 |
10 |
0.093
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.092
|
|
|
|
layer formation in cerebral cortex
|
GO:0021819 |
13 |
0.092
|
|
|
|
renal system process involved in regulation of blood volume
|
GO:0001977 |
4 |
0.092
|
|
|
|
regulation of circadian sleep wake cycle
|
GO:0042749 |
3 |
0.092
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.092
|
Rat |
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.092
|
|
|
|
regulation of response to osmotic stress
|
GO:0047484 |
3 |
0.092
|
Mouse |
|
|
cellular biogenic amine metabolic process
|
GO:0006576 |
28 |
0.091
|
|
|
|
development of primary male sexual characteristics
|
GO:0046546 |
88 |
0.091
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.091
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.091
|
Human Mouse Rat |
|
|
beta amyloid metabolic process
|
GO:0050435 |
14 |
0.090
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.090
|
|
|
|
hormone mediated signaling pathway
|
GO:0009755 |
23 |
0.089
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.089
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.089
|
|
|
|
nephron tubule development
|
GO:0072080 |
84 |
0.089
|
Mouse Rat |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.089
|
|
|
|
cellular response to gamma radiation
|
GO:0071480 |
4 |
0.089
|
|
|
|
regulation of monooxygenase activity
|
GO:0032768 |
7 |
0.088
|
Mouse |
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
43 |
0.088
|
|
|
|
response to corticosterone
|
GO:0051412 |
1 |
0.088
|
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
77 |
0.087
|
Rat |
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.087
|
|
|
|
positive regulation of protein tyrosine kinase activity
|
GO:0061098 |
10 |
0.087
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
87 |
0.087
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.087
|
|
|
|
neutral lipid metabolic process
|
GO:0006638 |
57 |
0.086
|
|
|
|
artery smooth muscle contraction
|
GO:0014824 |
2 |
0.086
|
|
|
|
tissue migration
|
GO:0090130 |
68 |
0.086
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.086
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
80 |
0.085
|
|
|
|
heart trabecula formation
|
GO:0060347 |
14 |
0.085
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.085
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.084
|
|
|
|
negative regulation of gluconeogenesis
|
GO:0045721 |
9 |
0.084
|
|
|
|
sterol transmembrane transport
|
GO:0035382 |
2 |
0.084
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.083
|
|
|
|
mammary gland duct morphogenesis
|
GO:0060603 |
38 |
0.082
|
|
|
|
water transport
|
GO:0006833 |
12 |
0.082
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.082
|
|
|
|
response to drug
|
GO:0042493 |
75 |
0.082
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
59 |
0.081
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.081
|
|
|
|
response to sterol
|
GO:0036314 |
4 |
0.080
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.080
|
|
|
|
regulation of muscle hypertrophy
|
GO:0014743 |
13 |
0.080
|
|
|
|
negative regulation of muscle cell apoptotic process
|
GO:0010656 |
9 |
0.079
|
|
|
|
neurological system process involved in regulation of systemic arterial blood pressure
|
GO:0001976 |
18 |
0.078
|
|
|
|
negative regulation of serotonin uptake
|
GO:0051612 |
2 |
0.077
|
|
|
|
response to monosaccharide
|
GO:0034284 |
67 |
0.076
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.076
|
Rat |
|
|
cellular alcohol biosynthetic process
|
GO:0044108 |
3 |
0.076
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.075
|
|
|
|
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway
|
GO:0051482 |
4 |
0.075
|
Human Mouse |
|
|
carboxylic acid transport
|
GO:0046942 |
100 |
0.075
|
|
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
25 |
0.075
|
|
|
|
positive regulation of nitric oxide biosynthetic process
|
GO:0045429 |
14 |
0.075
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.075
|
Mouse |
|
|
body fluid secretion
|
GO:0007589 |
53 |
0.074
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.074
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.074
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.074
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.074
|
|
|
|
cellular response to osmotic stress
|
GO:0071470 |
7 |
0.072
|
Mouse |
|
|
autophagic vacuole assembly
|
GO:0000045 |
13 |
0.072
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.072
|
Mouse Rat |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.072
|
Mouse |
|
|
antigen processing and presentation of peptide antigen via mhc class ii
|
GO:0002495 |
17 |
0.072
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.071
|
Mouse |
|
|
positive regulation of circadian rhythm
|
GO:0042753 |
7 |
0.071
|
|
|
|
digestion
|
GO:0007586 |
40 |
0.070
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
41 |
0.070
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.069
|
Rat |
|
|
mammary gland morphogenesis
|
GO:0060443 |
54 |
0.068
|
|
|
|
positive regulation of blood circulation
|
GO:1903524 |
22 |
0.068
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.068
|
Human |
|
|
antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii
|
GO:0002504 |
17 |
0.068
|
|
|
|
response to glucocorticoid
|
GO:0051384 |
20 |
0.068
|
Rat |
|
|
glycosylation
|
GO:0070085 |
62 |
0.067
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.067
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
86 |
0.067
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.067
|
|
|
|
lung vasculature development
|
GO:0060426 |
7 |
0.067
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.066
|
Rat |
|
|
regulation of blood vessel size
|
GO:0050880 |
56 |
0.066
|
Human Mouse Rat |
|
|
nitric oxide metabolic process
|
GO:0046209 |
25 |
0.066
|
|
|
|
regulation of nitric oxide synthase activity
|
GO:0050999 |
6 |
0.065
|
Mouse |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.065
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.065
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.065
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.065
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.065
|
|
|
|
peptidyl cysteine s nitrosylation
|
GO:0018119 |
4 |
0.064
|
|
|
|
cardiac cell development
|
GO:0055006 |
41 |
0.064
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
54 |
0.063
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.063
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.062
|
Rat |
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.062
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
59 |
0.062
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.062
|
|
|
|
necrotic cell death
|
GO:0070265 |
30 |
0.061
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.061
|
Human Mouse |
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.060
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.060
|
|
|
|
regulation of cardiac muscle hypertrophy
|
GO:0010611 |
13 |
0.060
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.060
|
|
|
|
neuroepithelial cell differentiation
|
GO:0060563 |
37 |
0.060
|
|
|
|
negative regulation of lipid metabolic process
|
GO:0045833 |
30 |
0.060
|
|
|
|
cholesterol import
|
GO:0070508 |
2 |
0.060
|
|
|
|
purine ribonucleoside biosynthetic process
|
GO:0046129 |
19 |
0.060
|
|
|
|
response to catecholamine
|
GO:0071869 |
4 |
0.060
|
|
|
|
lipid modification
|
GO:0030258 |
65 |
0.059
|
Human |
|
|
regulation of protein tyrosine kinase activity
|
GO:0061097 |
17 |
0.059
|
|
|
|
intestinal absorption
|
GO:0050892 |
13 |
0.059
|
|
|
|
negative regulation of muscle adaptation
|
GO:0014745 |
2 |
0.058
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.058
|
|
|
|
regulation of phospholipase activity
|
GO:0010517 |
9 |
0.058
|
Human |
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
79 |
0.058
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.058
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.058
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.058
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.058
|
Mouse |
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
34 |
0.057
|
Mouse |
|
|
regulation of long term neuronal synaptic plasticity
|
GO:0048169 |
19 |
0.057
|
|
|
|
cellular response to superoxide
|
GO:0071451 |
14 |
0.057
|
|
|
|
g protein coupled receptor signaling pathway involved in heart process
|
GO:0086103 |
4 |
0.057
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.057
|
|
|
|
regulation of plasma lipoprotein particle levels
|
GO:0097006 |
23 |
0.057
|
|
