Mus musculus

23 known processes

Alox12e

arachidonate lipoxygenase, epidermal

(Aliases: AW259591,e-LOX1,Aloxe,8-LOX,Alox12-ps2,Alox12-ps1)

Alox12e biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of keratinocyte differentiation GO:0045616 11 0.429
Mouse
keratinocyte differentiation GO:0030216 48 0.424
Mouse
cytokine mediated signaling pathway GO:0019221 115 0.387
cellular response to cytokine stimulus GO:0071345 189 0.278
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.267
lipid biosynthetic process GO:0008610 179 0.165
Mouse
lipid catabolic process GO:0016042 69 0.164
regulation of body fluid levels GO:0050878 162 0.159
Mouse
cellular amine metabolic process GO:0044106 44 0.147
hepatocyte apoptotic process GO:0097284 11 0.130
carboxylic acid biosynthetic process GO:0046394 86 0.124
Mouse
activation of immune response GO:0002253 138 0.124
wnt signaling pathway GO:0016055 188 0.123
cellular lipid metabolic process GO:0044255 323 0.120
gland development GO:0048732 330 0.117
leukocyte activation involved in immune response GO:0002366 126 0.110
regulation of defense response GO:0031347 233 0.108
epidermis development GO:0008544 187 0.105
Mouse
wound healing GO:0042060 157 0.103
hair follicle development GO:0001942 85 0.101
small molecule biosynthetic process GO:0044283 132 0.101
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.098
peptide transport GO:0015833 133 0.095
regulation of cellular amino acid metabolic process GO:0006521 5 0.088
organic acid biosynthetic process GO:0016053 86 0.088
Mouse
organic hydroxy compound metabolic process GO:1901615 203 0.087
response to radiation GO:0009314 165 0.087
camera type eye development GO:0043010 266 0.085
leukocyte differentiation GO:0002521 342 0.082
regulation of cell activation GO:0050865 289 0.082
fatty acid biosynthetic process GO:0006633 41 0.081
Mouse
inflammatory response GO:0006954 244 0.081
Mouse
tissue regeneration GO:0042246 22 0.081
hair cycle GO:0042633 90 0.077
cytokine metabolic process GO:0042107 71 0.077
defense response to bacterium GO:0042742 119 0.076
regulation of cell adhesion GO:0030155 154 0.076
acetylcholine secretion neurotransmission GO:0014055 2 0.075
multicellular organismal water homeostasis GO:0050891 23 0.074
Mouse
positive regulation of cytokine biosynthetic process GO:0042108 40 0.074
nucleotide metabolic process GO:0009117 332 0.073
cellular response to hormone stimulus GO:0032870 150 0.073
skin morphogenesis GO:0043589 38 0.072
cellular homeostasis GO:0019725 240 0.072
cellular amino acid metabolic process GO:0006520 103 0.071
epithelial cell development GO:0002064 159 0.070
cytokine production GO:0001816 319 0.069
cell adhesion GO:0007155 329 0.068
membrane organization GO:0061024 245 0.068
regulation of cytokine production GO:0001817 266 0.066
actin filament organization GO:0007015 113 0.066
regulation of cellular amine metabolic process GO:0033238 20 0.066
cell type specific apoptotic process GO:0097285 268 0.064
peptidyl tyrosine modification GO:0018212 145 0.064
protein maturation GO:0051604 176 0.064
regulation of t cell differentiation GO:0045580 83 0.063
lymphocyte differentiation GO:0030098 242 0.063
intermediate filament cytoskeleton organization GO:0045104 26 0.063
intermediate filament based process GO:0045103 27 0.061
regulation of hormone levels GO:0010817 211 0.061
molting cycle GO:0042303 90 0.061
g protein coupled receptor signaling pathway GO:0007186 243 0.061
regulation of response to wounding GO:1903034 189 0.060
purine ribonucleotide metabolic process GO:0009150 290 0.060
mapk cascade GO:0000165 281 0.060
amine metabolic process GO:0009308 45 0.059
hindbrain development GO:0030902 128 0.058
innate immune response GO:0045087 157 0.058
regulation of membrane potential GO:0042391 192 0.058
regulation of protein processing GO:0070613 96 0.058
spermatogenesis GO:0007283 284 0.058
extrinsic apoptotic signaling pathway GO:0097191 126 0.058
tumor necrosis factor mediated signaling pathway GO:0033209 13 0.057
nucleobase containing small molecule metabolic process GO:0055086 352 0.057
regulation of anatomical structure size GO:0090066 178 0.057
nitrogen compound transport GO:0071705 271 0.056
positive regulation of cell migration GO:0030335 109 0.056
protein processing GO:0016485 163 0.055
purine containing compound metabolic process GO:0072521 311 0.055
cytokine biosynthetic process GO:0042089 68 0.054
regulation of cytokine biosynthetic process GO:0042035 59 0.054
neuron death GO:0070997 154 0.053
intermediate filament organization GO:0045109 15 0.053
regulation of neuron death GO:1901214 134 0.053
regulation of proteolysis GO:0030162 164 0.052
regulation of epithelial cell proliferation GO:0050678 141 0.052
leukocyte mediated immunity GO:0002443 174 0.051
locomotory behavior GO:0007626 195 0.050
posttranscriptional regulation of gene expression GO:0010608 155 0.050
sensory perception GO:0007600 245 0.049
regulation of vesicle mediated transport GO:0060627 139 0.049
hair follicle morphogenesis GO:0031069 29 0.049
regulation of cell cycle GO:0051726 281 0.048
epithelial tube morphogenesis GO:0060562 303 0.047
monocarboxylic acid biosynthetic process GO:0072330 61 0.047
Mouse
protein secretion GO:0009306 111 0.046
regulation of protein serine threonine kinase activity GO:0071900 157 0.046
germ cell development GO:0007281 185 0.046
epidermis morphogenesis GO:0048730 33 0.046
insulin receptor signaling pathway GO:0008286 49 0.046
oxidation reduction process GO:0055114 342 0.045
Zebrafish Mouse
skin development GO:0043588 220 0.045
Mouse
negative regulation of molecular function GO:0044092 258 0.044
regulation of epidermis development GO:0045682 33 0.044
Mouse
epithelial cell proliferation GO:0050673 174 0.044
chemotaxis GO:0006935 247 0.044
regulation of reactive oxygen species metabolic process GO:2000377 40 0.042
cellular response to organonitrogen compound GO:0071417 145 0.042
embryonic placenta development GO:0001892 98 0.042
cell activation involved in immune response GO:0002263 126 0.042
defecation GO:0030421 1 0.041
ossification GO:0001503 216 0.041
branching morphogenesis of an epithelial tube GO:0048754 159 0.041
cd4 positive alpha beta t cell activation GO:0035710 45 0.040
organophosphate catabolic process GO:0046434 232 0.039
nucleoside metabolic process GO:0009116 246 0.038
nucleoside phosphate metabolic process GO:0006753 338 0.038
establishment of skin barrier GO:0061436 14 0.038
Mouse
regulation of endopeptidase activity GO:0052548 89 0.038
aromatic compound catabolic process GO:0019439 286 0.037
negative regulation of cell proliferation GO:0008285 296 0.037
positive regulation of defense response GO:0031349 124 0.037
cation transport GO:0006812 399 0.037
tissue remodeling GO:0048771 102 0.037
regulation of kinase activity GO:0043549 249 0.037
regulation of feeding behavior GO:0060259 3 0.037
regulation of water loss via skin GO:0033561 16 0.036
Mouse
response to organic cyclic compound GO:0014070 198 0.036
morphogenesis of a branching structure GO:0001763 203 0.035
peptidyl amino acid modification GO:0018193 336 0.035
t cell activation involved in immune response GO:0002286 43 0.035
microtubule cytoskeleton organization GO:0000226 157 0.035
skeletal system development GO:0001501 356 0.035
dna metabolic process GO:0006259 303 0.035
ribose phosphate metabolic process GO:0019693 291 0.035
adult behavior GO:0030534 135 0.035
protein catabolic process GO:0030163 221 0.035
regulation of secretion GO:0051046 274 0.035
negative regulation of neuron death GO:1901215 98 0.034
sensory organ morphogenesis GO:0090596 242 0.034
negative regulation of cell activation GO:0050866 111 0.034
neuron apoptotic process GO:0051402 142 0.034
positive regulation of inflammatory response GO:0050729 47 0.034
extracellular matrix organization GO:0030198 147 0.034
regulation of neuron apoptotic process GO:0043523 122 0.033
regulation of lymphocyte activation GO:0051249 240 0.033
immune effector process GO:0002252 321 0.033
regulation of protein kinase activity GO:0045859 232 0.033
positive regulation of mapk cascade GO:0043410 170 0.033
regulation of inflammatory response GO:0050727 147 0.032
regulation of lymphocyte differentiation GO:0045619 107 0.032
regulation of interleukin 8 production GO:0032677 3 0.032
positive regulation of epidermis development GO:0045684 13 0.032
Mouse
detection of stimulus GO:0051606 84 0.032
negative regulation of neuron apoptotic process GO:0043524 92 0.032
purine nucleotide metabolic process GO:0006163 302 0.032
monocarboxylic acid metabolic process GO:0032787 191 0.031
regulation of epidermal cell differentiation GO:0045604 21 0.031
Mouse
negative regulation of cytokine production GO:0001818 84 0.031
sensory perception of light stimulus GO:0050953 54 0.031
negative regulation of epithelial cell proliferation GO:0050680 64 0.031
regulation of peptidase activity GO:0052547 96 0.031
regulation of t cell activation GO:0050863 170 0.031
adaptive immune response GO:0002250 155 0.031
regulation of chemotaxis GO:0050920 53 0.030
alcohol metabolic process GO:0006066 116 0.030
t cell activation GO:0042110 289 0.030
regulation of intracellular transport GO:0032386 159 0.030
sulfur compound metabolic process GO:0006790 100 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.030
steroid biosynthetic process GO:0006694 47 0.030
leukocyte migration GO:0050900 124 0.030
metencephalon development GO:0022037 89 0.030
cell fate commitment GO:0045165 210 0.029
interleukin 8 production GO:0032637 4 0.029
response to peptide GO:1901652 136 0.029
lymphocyte activation involved in immune response GO:0002285 93 0.029
negative regulation of hormone biosynthetic process GO:0032353 4 0.029
regulation of canonical wnt signaling pathway GO:0060828 82 0.029
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.029
negative regulation of wnt signaling pathway GO:0030178 73 0.029
regulation of protein secretion GO:0050708 82 0.028
icosanoid metabolic process GO:0006690 33 0.028
negative regulation of proteolysis GO:0045861 74 0.028
carbohydrate biosynthetic process GO:0016051 74 0.028
cellular ketone metabolic process GO:0042180 84 0.028
cellular response to inorganic substance GO:0071241 37 0.028
cell substrate adhesion GO:0031589 130 0.028
water homeostasis GO:0030104 27 0.028
Mouse
ribonucleotide metabolic process GO:0009259 291 0.028
regulation of protein localization GO:0032880 231 0.027
organic cyclic compound catabolic process GO:1901361 295 0.027
steroid metabolic process GO:0008202 119 0.027
macromolecule catabolic process GO:0009057 281 0.027
carbohydrate homeostasis GO:0033500 128 0.027
regeneration GO:0031099 38 0.027
negative regulation of protein metabolic process GO:0051248 282 0.026
fat soluble vitamin biosynthetic process GO:0042362 4 0.026
glycosyl compound metabolic process GO:1901657 246 0.026
reactive oxygen species metabolic process GO:0072593 84 0.026
regulation of organ morphogenesis GO:2000027 144 0.026
b cell differentiation GO:0030183 78 0.026
positive regulation of dendritic cell dendrite assembly GO:2000549 1 0.026
negative regulation of intracellular signal transduction GO:1902532 167 0.026
cellular response to tumor necrosis factor GO:0071356 21 0.026
regulation of engulfment of apoptotic cell GO:1901074 2 0.026
regulation of cell growth GO:0001558 91 0.026
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.025
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.025
regulation of endocytosis GO:0030100 69 0.025
negative regulation of protein processing GO:0010955 79 0.025
response to light stimulus GO:0009416 135 0.025
regulation of wnt signaling pathway GO:0030111 123 0.025
fatty acid derivative metabolic process GO:1901568 33 0.025
sequestering of calcium ion GO:0051208 18 0.025
positive regulation of nervous system development GO:0051962 221 0.025
action potential GO:0001508 78 0.025
regulation of cell migration GO:0030334 219 0.025
positive regulation of hair follicle development GO:0051798 6 0.025
regulation of lymphocyte apoptotic process GO:0070228 41 0.025
cellular nitrogen compound catabolic process GO:0044270 280 0.025
regulation of mapk cascade GO:0043408 248 0.025
negative regulation of response to wounding GO:1903035 77 0.025
organelle localization GO:0051640 179 0.025
axonogenesis GO:0007409 274 0.025
purine nucleotide catabolic process GO:0006195 211 0.025
insulin secretion GO:0030073 89 0.025
organic hydroxy compound biosynthetic process GO:1901617 77 0.024
proteoglycan metabolic process GO:0006029 38 0.024
male gamete generation GO:0048232 285 0.024
platelet activation GO:0030168 40 0.024
regulation of secretion by cell GO:1903530 249 0.024
purine nucleoside catabolic process GO:0006152 205 0.024
response to growth factor GO:0070848 198 0.023
carbohydrate derivative biosynthetic process GO:1901137 183 0.023
skeletal system morphogenesis GO:0048705 203 0.023
peptide hormone secretion GO:0030072 109 0.023
macrophage activation GO:0042116 27 0.023
hormone metabolic process GO:0042445 86 0.023
female gonad development GO:0008585 71 0.023
mitotic cell cycle GO:0000278 195 0.023
midgut development GO:0007494 4 0.023
regulation of adaptive immune response GO:0002819 90 0.023
i kappab kinase nf kappab signaling GO:0007249 85 0.023
negative regulation of growth GO:0045926 99 0.023
regulation of homeostatic process GO:0032844 182 0.023
unsaturated fatty acid metabolic process GO:0033559 31 0.022
developmental maturation GO:0021700 193 0.022
vitamin metabolic process GO:0006766 23 0.022
arachidonic acid metabolite production involved in inflammatory response GO:0002538 2 0.022
Mouse
cellular response to carbohydrate stimulus GO:0071322 50 0.022
modification dependent macromolecule catabolic process GO:0043632 133 0.022
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.022
cellular chemical homeostasis GO:0055082 215 0.022
morphogenesis of a branching epithelium GO:0061138 193 0.022
response to monosaccharide GO:0034284 67 0.022
metanephric tubule development GO:0072170 18 0.022
lipid transport GO:0006869 98 0.022
regulation of angiogenesis GO:0045765 81 0.022
apoptotic signaling pathway GO:0097190 306 0.021
urogenital system development GO:0001655 261 0.021
single organism cell adhesion GO:0098602 156 0.021
regulation of organelle organization GO:0033043 289 0.021
regulation of establishment of protein localization GO:0070201 181 0.021
negative regulation of lymphocyte activation GO:0051250 91 0.021
connective tissue development GO:0061448 179 0.021
cell growth GO:0016049 130 0.021
canonical wnt signaling pathway GO:0060070 130 0.021
neutrophil chemotaxis GO:0030593 36 0.021
regulation of macrophage activation GO:0043030 17 0.021
organ growth GO:0035265 117 0.021
lipoxin a4 biosynthetic process GO:2001303 1 0.021
carbohydrate derivative catabolic process GO:1901136 231 0.021
mitochondrion organization GO:0007005 134 0.021
cytoplasmic transport GO:0016482 234 0.021
regulation of protein maturation GO:1903317 96 0.021
positive regulation of cell motility GO:2000147 116 0.021
regulation of cytoplasmic transport GO:1903649 112 0.021
peptidyl tyrosine phosphorylation GO:0018108 143 0.021
rho protein signal transduction GO:0007266 32 0.021
regulation of cell substrate adhesion GO:0010810 73 0.020
cell differentiation involved in embryonic placenta development GO:0060706 26 0.020
positive regulation of protein modification process GO:0031401 299 0.020
blood coagulation GO:0007596 76 0.020
extracellular structure organization GO:0043062 148 0.020
positive regulation of programmed cell death GO:0043068 218 0.020
ribonucleotide catabolic process GO:0009261 208 0.020
positive regulation of canonical wnt signaling pathway GO:0090263 29 0.020
neuron projection extension GO:1990138 64 0.020
cellular response to peptide GO:1901653 92 0.020
cellular response to starvation GO:0009267 57 0.020
response to inorganic substance GO:0010035 96 0.020
regulation of hydrolase activity GO:0051336 246 0.019
calcium ion homeostasis GO:0055074 127 0.019
glycoprotein metabolic process GO:0009100 116 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.019
negative regulation of cellular protein metabolic process GO:0032269 247 0.019
rhodopsin mediated signaling pathway GO:0016056 4 0.019
defense response to other organism GO:0098542 197 0.019
nucleotide catabolic process GO:0009166 217 0.019
biomineral tissue development GO:0031214 64 0.019
respiratory system development GO:0060541 190 0.019
translation GO:0006412 93 0.019
blood vessel morphogenesis GO:0048514 285 0.019
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.018
multicellular organismal homeostasis GO:0048871 164 0.018
regulation of lipid metabolic process GO:0019216 118 0.018
positive regulation of growth GO:0045927 104 0.018
ribonucleoside metabolic process GO:0009119 245 0.018
ras protein signal transduction GO:0007265 77 0.018
cellular response to insulin stimulus GO:0032869 78 0.018
heterocycle catabolic process GO:0046700 280 0.018
response to organonitrogen compound GO:0010243 246 0.018
negative regulation of endopeptidase activity GO:0010951 44 0.018
cerebellum development GO:0021549 77 0.018
respiratory tube development GO:0030323 167 0.018
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.018
sphingolipid metabolic process GO:0006665 45 0.018
Mouse
glucose homeostasis GO:0042593 128 0.018
exocytosis GO:0006887 121 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.017
regulation of protein transport GO:0051223 163 0.017
engulfment of apoptotic cell GO:0043652 3 0.017
exocrine system development GO:0035272 45 0.017
cellular response to organic cyclic compound GO:0071407 87 0.017
leukocyte apoptotic process GO:0071887 71 0.017
vestibular nucleus development GO:0021750 2 0.017
regulation of leukocyte differentiation GO:1902105 159 0.017
striated muscle contraction GO:0006941 45 0.017
cellular modified amino acid metabolic process GO:0006575 63 0.017
nucleoside catabolic process GO:0009164 206 0.017
myeloid cell differentiation GO:0030099 233 0.017
blood circulation GO:0008015 195 0.017
regulation of cell cycle process GO:0010564 160 0.017
cell junction assembly GO:0034329 52 0.017
ear development GO:0043583 200 0.017
positive regulation of cell growth GO:0030307 33 0.016
positive regulation of interleukin 8 production GO:0032757 2 0.016
cellular response to nutrient levels GO:0031669 64 0.016
positive regulation of innate immune response GO:0045089 80 0.016
regulation of inositol phosphate biosynthetic process GO:0010919 3 0.016
nucleoside phosphate catabolic process GO:1901292 222 0.016
phagocytosis GO:0006909 66 0.016
purine ribonucleoside catabolic process GO:0046130 205 0.016
organophosphate biosynthetic process GO:0090407 122 0.016
response to endoplasmic reticulum stress GO:0034976 53 0.016
regulation of cellular ketone metabolic process GO:0010565 66 0.016
cellular response to oxidative stress GO:0034599 76 0.016
t helper cell differentiation GO:0042093 28 0.016
endomembrane system organization GO:0010256 147 0.016
ribonucleoside triphosphate catabolic process GO:0009203 199 0.016
negative regulation of hormone metabolic process GO:0032351 4 0.016
regulation of nucleotide metabolic process GO:0006140 169 0.016
dna dealkylation GO:0035510 11 0.016
cellular response to peptide hormone stimulus GO:0071375 92 0.016
ribonucleoside catabolic process GO:0042454 206 0.016
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.016
cellular response to molecule of bacterial origin GO:0071219 83 0.016
placenta development GO:0001890 140 0.016
regulation of neuron differentiation GO:0045664 281 0.016
retina development in camera type eye GO:0060041 119 0.016
response to stilbenoid GO:0035634 22 0.016
negative regulation of protein maturation GO:1903318 79 0.016
cellular component assembly involved in morphogenesis GO:0010927 139 0.016
regulation of hormone secretion GO:0046883 88 0.016
regulation of map kinase activity GO:0043405 120 0.016
cellular carbohydrate metabolic process GO:0044262 119 0.016
sa node cell to atrial cardiac muscle cell signalling GO:0086018 4 0.015
muscle cell differentiation GO:0042692 261 0.015
purine containing compound catabolic process GO:0072523 213 0.015
regulation of cell motility GO:2000145 236 0.015
cation homeostasis GO:0055080 212 0.015
transmembrane transport GO:0055085 412 0.015
response to tumor necrosis factor GO:0034612 26 0.015
cellular macromolecule catabolic process GO:0044265 206 0.015
cellular response to dna damage stimulus GO:0006974 207 0.015
stem cell differentiation GO:0048863 268 0.015
sperm motility GO:0030317 47 0.015
nucleoside triphosphate metabolic process GO:0009141 230 0.015
negative regulation of apoptotic signaling pathway GO:2001234 104 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
cochlea development GO:0090102 35 0.015
cell cell junction organization GO:0045216 72 0.015
t cell differentiation GO:0030217 174 0.015
maintenance of location GO:0051235 89 0.015
response to oxidative stress GO:0006979 123 0.015
positive regulation of cell development GO:0010720 237 0.015
stem cell development GO:0048864 219 0.015
negative regulation of protein transport GO:0051224 46 0.015
rhythmic process GO:0048511 174 0.015
positive regulation of protein kinase activity GO:0045860 144 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.015
response to reactive oxygen species GO:0000302 56 0.015
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.015
lymphocyte mediated immunity GO:0002449 139 0.015
positive regulation of sodium ion transport GO:0010765 13 0.015
oxygen homeostasis GO:0032364 2 0.014
lens development in camera type eye GO:0002088 62 0.014
cellular response to amino acid stimulus GO:0071230 29 0.014
myeloid leukocyte differentiation GO:0002573 119 0.014
regulation of system process GO:0044057 200 0.014
positive regulation of organelle organization GO:0010638 128 0.014
fatty acid metabolic process GO:0006631 121 0.014
hormone biosynthetic process GO:0042446 16 0.014
positive regulation of cell activation GO:0050867 158 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
regulation of translation GO:0006417 71 0.014
purine ribonucleotide catabolic process GO:0009154 208 0.014
regulation of plasma lipoprotein particle levels GO:0097006 23 0.014
glycosyl compound catabolic process GO:1901658 206 0.014
mitotic cell cycle process GO:1903047 159 0.014
peptidyl serine modification GO:0018209 83 0.013
extraocular skeletal muscle development GO:0002074 2 0.013
response to molecule of bacterial origin GO:0002237 143 0.013
positive regulation of t cell differentiation GO:0045582 52 0.013
b cell activation GO:0042113 161 0.013
blastocyst development GO:0001824 80 0.013
regulation of actin cytoskeleton organization GO:0032956 84 0.013
regulation of mitotic cell cycle GO:0007346 126 0.013
chromatin organization GO:0006325 206 0.013
homeostasis of number of cells GO:0048872 210 0.013
circulatory system process GO:0003013 197 0.013
protein targeting GO:0006605 143 0.013
response to starvation GO:0042594 65 0.013
pigment granule localization GO:0051875 13 0.013
terpenoid metabolic process GO:0006721 25 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.013
protein localization to membrane GO:0072657 108 0.013
single organismal cell cell adhesion GO:0016337 131 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
positive regulation of cytokine production GO:0001819 174 0.013
t cell apoptotic process GO:0070231 39 0.013
response to extracellular stimulus GO:0009991 127 0.013
detection of abiotic stimulus GO:0009582 60 0.013
negative regulation of transferase activity GO:0051348 85 0.013
cellular lipid catabolic process GO:0044242 52 0.013
cell junction organization GO:0034330 77 0.013
negative regulation of hydrolase activity GO:0051346 71 0.013
positive regulation of protein phosphorylation GO:0001934 242 0.013
regulation of t helper 1 cell cytokine production GO:2000554 1 0.013
positive regulation of sodium ion transmembrane transport GO:1902307 4 0.013
phosphatidylethanolamine biosynthetic process GO:0006646 2 0.012
neuron projection guidance GO:0097485 141 0.012
negative regulation of kinase activity GO:0033673 81 0.012
sequestering of metal ion GO:0051238 19 0.012
syncytium formation by plasma membrane fusion GO:0000768 42 0.012
response to uv GO:0009411 44 0.012
neuroblast differentiation GO:0014016 2 0.012
negative regulation of immune system process GO:0002683 209 0.012
regulation of peptide transport GO:0090087 91 0.012
regulation of tissue remodeling GO:0034103 38 0.012
regulation of protein kinase b signaling GO:0051896 56 0.012
cell chemotaxis GO:0060326 81 0.012
microtubule based process GO:0007017 236 0.012
protein localization to organelle GO:0033365 185 0.012
homotypic cell cell adhesion GO:0034109 28 0.012
response to metal ion GO:0010038 47 0.012
regulation of ion transport GO:0043269 215 0.012
regulation of monocyte chemotaxis GO:0090025 3 0.012
negative regulation of keratinocyte differentiation GO:0045617 4 0.012
multicellular organismal signaling GO:0035637 91 0.012
negative regulation of synapse assembly GO:0051964 3 0.012
regulation of organ growth GO:0046620 61 0.012
regulation of leukocyte apoptotic process GO:2000106 56 0.012
atp metabolic process GO:0046034 75 0.012
acute inflammatory response GO:0002526 41 0.012
sa node cell action potential GO:0086015 4 0.012
interleukin 8 secretion GO:0072606 3 0.012
positive regulation of jun kinase activity GO:0043507 30 0.012
lipid localization GO:0010876 126 0.012
smooth muscle contraction GO:0006939 44 0.012
negative regulation of leukocyte apoptotic process GO:2000107 31 0.012
visual perception GO:0007601 52 0.012
multi multicellular organism process GO:0044706 109 0.012
response to amino acid GO:0043200 37 0.012
cellular glucose homeostasis GO:0001678 52 0.012
regulation of cellular catabolic process GO:0031329 242 0.012
negative regulation of t cell apoptotic process GO:0070233 18 0.012
purine nucleoside metabolic process GO:0042278 241 0.012
negative regulation of t cell activation GO:0050868 65 0.011
cell recognition GO:0008037 83 0.011
epithelial tube formation GO:0072175 130 0.011
positive regulation of plasminogen activation GO:0010756 2 0.011
alpha beta t cell activation GO:0046631 91 0.011
epinephrine secretion GO:0048242 1 0.011
cellular metal ion homeostasis GO:0006875 151 0.011

Alox12e disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
nervous system disease DOID:863 0 0.032
eye and adnexa disease DOID:1492 0 0.017
eye disease DOID:5614 0 0.017
sensory system disease DOID:0050155 0 0.017
retinal degeneration DOID:8466 0 0.017
retinal disease DOID:5679 0 0.017
integumentary system disease DOID:16 0 0.014