Mus musculus

491 known processes

Bmp4

bone morphogenetic protein 4

(Aliases: Bmp2b-1,Bmp-4,Bmp2b,Bmp2b1)

Bmp4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 1.000
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 1.000
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 1.000
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 1.000
Zebrafish
pyramidal neuron migration GO:0021852 1 1.000
embryonic organ morphogenesis GO:0048562 276 1.000
mesenchyme development GO:0060485 152 1.000
neural crest cell migration involved in autonomic nervous system development GO:1901166 5 1.000
stem cell development GO:0048864 219 1.000
Mouse Fly
appendage morphogenesis GO:0035107 149 1.000
mesenchymal cell differentiation GO:0048762 107 1.000
endodermal cell fate commitment GO:0001711 12 1.000
Zebrafish
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 1.000
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 1.000
gastrulation GO:0007369 116 1.000
regulation of bmp signaling pathway GO:0030510 60 1.000
bmp signaling pathway GO:0030509 93 1.000
stem cell differentiation GO:0048863 268 1.000
positive regulation of transcription by glucose GO:0046016 3 1.000
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 1.000
embryonic skeletal system development GO:0048706 120 1.000
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 1.000
regionalization GO:0003002 337 1.000
branching morphogenesis of an epithelial tube GO:0048754 159 1.000
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 1.000
Mouse
respiratory system development GO:0060541 190 1.000
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 1.000
positive regulation of transcription from rna polymerase ii promoter by glucose GO:0000432 3 1.000
limb morphogenesis GO:0035108 149 1.000
axial mesodermal cell fate commitment GO:0048322 1 1.000
regulation of apoptotic process involved in outflow tract morphogenesis GO:1902256 2 1.000
neural tube closure GO:0001843 90 1.000
regulation of transcription involved in primary germ layer cell fate commitment GO:0060796 2 1.000
Zebrafish
regulation of heart morphogenesis GO:2000826 22 1.000
Human
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 1.000
cardiac endothelial cell differentiation GO:0003348 4 1.000
chondrocyte development GO:0002063 24 1.000
branching involved in ureteric bud morphogenesis GO:0001658 56 1.000
endocardial cell differentiation GO:0060956 4 1.000
mesenchymal cell development GO:0014031 93 1.000
Mouse
regulation of planar cell polarity pathway involved in ventricular septum morphogenesis GO:2000148 1 1.000
floor plate morphogenesis GO:0033505 3 1.000
ventricular zone neuroblast division GO:0021847 3 1.000
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis GO:2000166 1 1.000
metanephric capsule specification GO:0072267 1 1.000
positive regulation of mesenchymal cell proliferation GO:0002053 33 1.000
kidney development GO:0001822 213 1.000
closure of optic fissure GO:0061386 2 1.000
regulation of mesodermal cell fate specification GO:0042661 5 1.000
determination of heart left right asymmetry GO:0061371 48 1.000
Zebrafish
regulation of astrocyte differentiation GO:0048710 20 1.000
Mouse
smoothened signaling pathway GO:0007224 105 1.000
Human
endodermal cell fate specification GO:0001714 4 1.000
Zebrafish
negative regulation of apoptotic process involved in outflow tract morphogenesis GO:1902257 2 1.000
lateral mesoderm morphogenesis GO:0048369 3 1.000
formation of primary germ layer GO:0001704 77 1.000
urogenital system development GO:0001655 261 1.000
lung induction GO:0060492 3 1.000
mesenchyme morphogenesis GO:0072132 32 1.000
Mouse
nephron development GO:0072006 109 1.000
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 1.000
mesonephric tubule development GO:0072164 94 1.000
regulation of vascular wound healing GO:0061043 2 1.000
left lung development GO:0060459 4 1.000
apoptotic process involved in outflow tract morphogenesis GO:0003275 2 1.000
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 1.000
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 1.000
auditory receptor cell fate determination GO:0042668 3 1.000
chondrocyte differentiation GO:0002062 72 1.000
cell proliferation in midbrain GO:0033278 2 1.000
embryonic heart tube anterior posterior pattern specification GO:0035054 3 1.000
Mouse
roof plate formation GO:0021509 1 1.000
ventricular septum morphogenesis GO:0060412 27 1.000
embryonic viscerocranium morphogenesis GO:0048703 8 1.000
nephron tubule morphogenesis GO:0072078 68 1.000
negative regulation of transcription from rna polymerase ii promoter by glucose GO:0000433 1 1.000
skeletal system development GO:0001501 356 1.000
mesenchymal cell apoptotic process involved in nephron morphogenesis GO:1901145 4 1.000
stem cell maintenance GO:0019827 130 1.000
Fly
lung development GO:0030324 164 1.000
cell proliferation in hindbrain GO:0021534 10 1.000
kidney epithelium development GO:0072073 121 1.000
anterior commissure morphogenesis GO:0021960 6 1.000
ureteric bud development GO:0001657 94 1.000
formation of radial glial scaffolds GO:0021943 4 1.000
regulation of organ morphogenesis GO:2000027 144 1.000
regulation of nephron tubule epithelial cell differentiation GO:0072182 9 0.999
endodermal cell fate determination GO:0007493 2 0.999
neural tube patterning GO:0021532 43 0.999
lateral mesodermal cell differentiation GO:0048371 3 0.999
embryonic heart tube development GO:0035050 65 0.999
Zebrafish Mouse
embryonic skeletal system morphogenesis GO:0048704 91 0.999
epithelial tube morphogenesis GO:0060562 303 0.999
neural tube development GO:0021915 160 0.999
regulation of epithelial cell proliferation GO:0050678 141 0.999
neural crest cell migration GO:0001755 32 0.999
cardiocyte differentiation GO:0035051 87 0.999
Human Fly
regulation of cell proliferation involved in heart morphogenesis GO:2000136 15 0.999
Human
cardiac chamber development GO:0003205 108 0.999
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus GO:1901522 7 0.999
morphogenesis of a branching epithelium GO:0061138 193 0.999
hindlimb morphogenesis GO:0035137 42 0.999
mesodermal cell fate specification GO:0007501 11 0.999
Zebrafish
heart formation GO:0060914 16 0.999
Human
regulation of chondrocyte differentiation GO:0032330 33 0.999
cardioblast migration to the midline involved in heart field formation GO:0060975 1 0.999
locus ceruleus development GO:0021703 1 0.999
neuron projection guidance GO:0097485 141 0.999
noradrenergic neuron differentiation GO:0003357 6 0.999
negative regulation of mesodermal cell fate specification GO:0042662 3 0.999
renal vesicle induction GO:0072034 3 0.999
embryonic skeletal joint morphogenesis GO:0060272 11 0.999
pituitary gland development GO:0021983 38 0.999
carbon catabolite activation of transcription GO:0045991 4 0.999
forebrain morphogenesis GO:0048853 17 0.999
renal system development GO:0072001 225 0.999
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.999
ear morphogenesis GO:0042471 118 0.999
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.999
odontogenesis GO:0042476 78 0.999
carbon catabolite repression of transcription GO:0045013 1 0.999
cardiac muscle tissue development GO:0048738 130 0.999
Human Mouse
midbrain hindbrain boundary morphogenesis GO:0021555 4 0.999
cardiac muscle tissue morphogenesis GO:0055008 44 0.999
Mouse
neural tube formation GO:0001841 108 0.999
regulation of planar cell polarity pathway involved in outflow tract morphogenesis GO:2000163 1 0.999
clara cell differentiation GO:0060486 4 0.999
axis elongation involved in somitogenesis GO:0090245 4 0.999
metanephric nephron tubule formation GO:0072289 4 0.999
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.999
heart morphogenesis GO:0003007 178 0.999
Human Zebrafish Mouse
lateral mesoderm formation GO:0048370 3 0.999
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.998
positive regulation of bmp signaling pathway GO:0030513 23 0.998
negative regulation of bmp signaling pathway GO:0030514 35 0.998
endocardial cushion formation GO:0003272 13 0.998
regulation of cardiac muscle tissue development GO:0055024 31 0.998
Human
hair follicle development GO:0001942 85 0.998
positive regulation of ureteric bud formation GO:0072107 3 0.998
glomerular mesangial cell development GO:0072144 3 0.998
nephrogenic mesenchyme morphogenesis GO:0072134 2 0.998
telencephalon development GO:0021537 186 0.998
somitogenesis GO:0001756 69 0.998
Mouse
mesenchymal cell proliferation GO:0010463 44 0.998
retinal blood vessel morphogenesis GO:0061304 3 0.998
forebrain ventricular zone progenitor cell division GO:0021869 6 0.998
glomerular mesangial cell differentiation GO:0072008 3 0.998
trophectodermal cellular morphogenesis GO:0001831 3 0.998
skeletal system morphogenesis GO:0048705 203 0.998
renal capsule specification GO:0072130 1 0.998
hindbrain tangential cell migration GO:0021934 2 0.998
renal tubule development GO:0061326 87 0.998
cardiac septum morphogenesis GO:0060411 46 0.998
camera type eye development GO:0043010 266 0.998
embryonic heart tube formation GO:0003144 1 0.998
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.998
negative regulation of epithelial cell proliferation GO:0050680 64 0.998
negative regulation of cardiac chamber morphogenesis GO:1901220 2 0.998
epithelial tube formation GO:0072175 130 0.998
brain morphogenesis GO:0048854 32 0.998
primary prostatic bud elongation GO:0060516 2 0.998
positive regulation of lens epithelial cell proliferation GO:2001111 1 0.998
atrial septum primum morphogenesis GO:0003289 3 0.997
epithelial cell maturation involved in prostate gland development GO:0060743 4 0.997
positive regulation of transcription from rna polymerase iii promoter GO:0045945 1 0.997
positive regulation of stem cell proliferation GO:2000648 59 0.997
Rat
astrocyte fate commitment GO:0060018 4 0.997
negative regulation of endodermal cell differentiation GO:1903225 1 0.997
Zebrafish
mesodermal cell fate commitment GO:0001710 17 0.997
negative regulation of cell fate specification GO:0009996 4 0.997
Zebrafish
lung morphogenesis GO:0060425 50 0.997
heart field specification GO:0003128 6 0.997
Human
vascular wound healing GO:0061042 3 0.997
digestive tract development GO:0048565 190 0.997
cardiac chamber morphogenesis GO:0003206 93 0.997
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.997
metanephric mesenchyme morphogenesis GO:0072133 4 0.997
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072040 4 0.997
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.997
mesangial cell differentiation GO:0072007 4 0.997
morphogenesis of embryonic epithelium GO:0016331 159 0.997
ureteric bud morphogenesis GO:0060675 62 0.997
axon guidance GO:0007411 141 0.997
nephron morphogenesis GO:0072028 69 0.996
canonical wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation GO:0061324 2 0.996
prostate gland stromal morphogenesis GO:0060741 2 0.996
wnt signaling pathway involved in somitogenesis GO:0090244 4 0.996
limb development GO:0060173 166 0.996
face morphogenesis GO:0060325 29 0.996
negative regulation of planar cell polarity pathway involved in heart morphogenesis GO:2000160 1 0.996
positive regulation of cardioblast differentiation GO:0051891 3 0.996
otolith morphogenesis GO:0032474 3 0.996
cardiac muscle cell differentiation GO:0055007 69 0.996
Human
embryonic skeletal joint development GO:0072498 13 0.996
embryonic heart tube morphogenesis GO:0003143 51 0.996
Zebrafish
embryonic camera type eye development GO:0031076 36 0.996
trachea formation GO:0060440 3 0.996
negative regulation of axon extension GO:0030517 19 0.996
chemotaxis GO:0006935 247 0.996
Human Fly
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.996
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.996
digestive system development GO:0055123 200 0.995
metanephric capsule formation GO:0072266 1 0.995
skeletal muscle organ development GO:0060538 163 0.995
Human Mouse
epithelial cell proliferation GO:0050673 174 0.995
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.995
mesoderm formation GO:0001707 62 0.995
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.995
regulation of lens epithelial cell proliferation GO:2001109 1 0.995
cardiac septum development GO:0003279 59 0.995
cardiac right atrium morphogenesis GO:0003213 3 0.995
regulation of kidney development GO:0090183 40 0.995
inner ear receptor cell differentiation GO:0060113 61 0.995
retinal ganglion cell axon guidance GO:0031290 18 0.995
retina vasculature development in camera type eye GO:0061298 17 0.995
rostrocaudal neural tube patterning GO:0021903 12 0.995
mesodermal cell differentiation GO:0048333 22 0.994
left lung morphogenesis GO:0060460 3 0.994
positive regulation of hh target transcription factor activity GO:0007228 3 0.994
paraxial mesodermal cell differentiation GO:0048342 2 0.994
inner cell mass cellular morphogenesis GO:0001828 1 0.994
growth plate cartilage chondrocyte development GO:0003431 3 0.994
negative regulation of stem cell maintenance GO:1902455 4 0.994
trachea cartilage morphogenesis GO:0060535 4 0.994
regulation of cell migration involved in sprouting angiogenesis GO:0090049 4 0.994
regulation of cardioblast differentiation GO:0051890 3 0.994
transforming growth factor beta receptor signaling pathway involved in primitive streak formation GO:0090010 1 0.994
globus pallidus development GO:0021759 2 0.994
cardioblast migration GO:0003260 1 0.994
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.994
regulation of endodermal cell differentiation GO:1903224 2 0.993
Zebrafish
ossification GO:0001503 216 0.993
mammary gland morphogenesis GO:0060443 54 0.993
nephrogenic mesenchyme development GO:0072076 3 0.993
epithelial mesenchymal signaling involved in prostate gland development GO:0060738 2 0.993
negative regulation of photoreceptor cell differentiation GO:0046533 4 0.993
trophectodermal cell differentiation GO:0001829 21 0.993
cardiogenic plate morphogenesis GO:0003142 1 0.993
negative regulation of neuron differentiation GO:0045665 101 0.993
regulation of gastrulation GO:0010470 16 0.993
Zebrafish
embryonic eye morphogenesis GO:0048048 29 0.993
tendon cell differentiation GO:0035990 4 0.992
dichotomous subdivision of terminal units involved in ureteric bud branching GO:0060678 1 0.992
endoderm development GO:0007492 45 0.992
Zebrafish Mouse
prostate gland morphogenesis GO:0060512 32 0.992
sensory organ morphogenesis GO:0090596 242 0.992
osteoblast development GO:0002076 17 0.992
metanephros development GO:0001656 79 0.992
otic placode formation GO:0043049 1 0.992
branching involved in salivary gland morphogenesis GO:0060445 26 0.992
striated muscle tissue development GO:0014706 293 0.992
Human Mouse
mesonephric epithelium development GO:0072163 94 0.992
negative regulation of transcription by glucose GO:0045014 1 0.991
kidney mesenchyme morphogenesis GO:0072131 4 0.991
mesoderm development GO:0007498 100 0.991
negative regulation of astrocyte differentiation GO:0048712 10 0.991
stem cell proliferation GO:0072089 117 0.991
regulation of muscle tissue development GO:1901861 97 0.991
Human Mouse
retina development in camera type eye GO:0060041 119 0.990
Rat
positive regulation of wnt signaling pathway GO:0030177 45 0.990
Mouse
embryonic heart tube left right pattern formation GO:0060971 5 0.990
negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis GO:2000149 1 0.990
kidney morphogenesis GO:0060993 83 0.990
cardiac ventricle development GO:0003231 83 0.990
regulation of osteoblast proliferation GO:0033688 15 0.990
Mouse
epithelial cell development GO:0002064 159 0.990
cell proliferation involved in kidney development GO:0072111 14 0.990
neural crest cell development GO:0014032 48 0.990
positive regulation of cell migration involved in sprouting angiogenesis GO:0090050 3 0.990
commitment of neuronal cell to specific neuron type in forebrain GO:0021902 7 0.990
primary neural tube formation GO:0014020 95 0.990
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.989
mesendoderm development GO:0048382 3 0.989
sinoatrial node cell differentiation GO:0060921 3 0.989
blood vessel morphogenesis GO:0048514 285 0.989
nephron tubule development GO:0072080 84 0.989
mesodermal cell fate determination GO:0007500 1 0.989
positive regulation of heart growth GO:0060421 18 0.989
axial mesodermal cell fate specification GO:0048327 1 0.989
positive regulation of cardiac muscle cell proliferation GO:0060045 15 0.989
negative regulation of chondrocyte differentiation GO:0032331 13 0.988
forebrain generation of neurons GO:0021872 63 0.988
chondrocyte hypertrophy GO:0003415 4 0.988
cartilage condensation GO:0001502 18 0.987
gland development GO:0048732 330 0.987
carbon catabolite regulation of transcription GO:0045990 4 0.987
positive regulation of tendon cell differentiation GO:2001051 1 0.987
negative regulation of apoptotic process involved in morphogenesis GO:1902338 6 0.987
negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:2000162 1 0.987
cerebral cortex radially oriented cell migration GO:0021799 31 0.987
positive regulation of vascular wound healing GO:0035470 1 0.986
regulation of planar cell polarity pathway involved in neural tube closure GO:2000167 1 0.986
positive regulation of epithelial cell migration GO:0010634 19 0.986
Human
hepaticobiliary system development GO:0061008 67 0.986
Zebrafish Rat
lens morphogenesis in camera type eye GO:0002089 24 0.986
blastocyst development GO:0001824 80 0.986
smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation GO:0021938 4 0.986
positive regulation of epithelial cell proliferation GO:0050679 68 0.986
epithelial to mesenchymal transition GO:0001837 47 0.985
Mouse
cartilage development GO:0051216 140 0.985
regulation of cell adhesion GO:0030155 154 0.985
bmp signaling pathway involved in heart development GO:0061312 2 0.985
Human Zebrafish
prostate epithelial cord elongation GO:0060523 3 0.985
connective tissue development GO:0061448 179 0.985
cerebellar granule cell precursor proliferation GO:0021930 10 0.985
spinal cord association neuron differentiation GO:0021527 14 0.985
foregut morphogenesis GO:0007440 12 0.985
metanephric mesenchymal cell proliferation involved in metanephros development GO:0072136 2 0.985
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 4 0.985
ventricular cardiac muscle cell differentiation GO:0055012 17 0.984
mesonephros development GO:0001823 97 0.984
spinal cord development GO:0021510 81 0.984
orbitofrontal cortex development GO:0021769 2 0.984
tangential migration from the subventricular zone to the olfactory bulb GO:0022028 5 0.983
regulation of cardiac cell fate specification GO:2000043 1 0.983
midbrain hindbrain boundary maturation GO:0021732 1 0.983
positive regulation of growth GO:0045927 104 0.983
primitive streak formation GO:0090009 10 0.983
Mouse
positive regulation of skeletal muscle tissue regeneration GO:0043415 4 0.983
cell migration involved in gastrulation GO:0042074 13 0.983
tendon formation GO:0035992 4 0.983
renal capsule morphogenesis GO:0072128 1 0.983
nucleus accumbens development GO:0021768 1 0.983
positive regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901228 4 0.982
striated muscle cell development GO:0055002 125 0.982
Human Mouse
growth plate cartilage development GO:0003417 14 0.982
lens development in camera type eye GO:0002088 62 0.982
olfactory lobe development GO:0021988 32 0.982
epithelial to mesenchymal transition involved in endocardial cushion formation GO:0003198 10 0.982
epithelial tube branching involved in lung morphogenesis GO:0060441 28 0.982
prostate gland morphogenetic growth GO:0060737 4 0.982
respiratory tube development GO:0030323 167 0.982
negative regulation of cardiac muscle tissue development GO:0055026 8 0.982
positive regulation of mesenchymal cell proliferation involved in ureter development GO:2000729 3 0.981
growth plate cartilage chondrocyte growth GO:0003430 2 0.981
regulation of cardiac muscle tissue growth GO:0055021 26 0.981
metanephric nephron morphogenesis GO:0072273 19 0.981
Human
liver development GO:0001889 66 0.980
Zebrafish Rat
aorta morphogenesis GO:0035909 22 0.980
retinal rod cell differentiation GO:0060221 2 0.980
olfactory bulb interneuron development GO:0021891 7 0.980
branching involved in labyrinthine layer morphogenesis GO:0060670 9 0.979
heart trabecula formation GO:0060347 14 0.979
embryonic appendage morphogenesis GO:0035113 126 0.979
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.979
cell adhesion mediated by integrin GO:0033627 18 0.979
regulation of osteoblast differentiation GO:0045667 67 0.978
Human Mouse Rat
membranous septum morphogenesis GO:0003149 6 0.978
bone morphogenesis GO:0060349 78 0.978
regulation of establishment of planar polarity involved in neural tube closure GO:0090178 15 0.978
cerebral cortex radial glia guided migration GO:0021801 17 0.978
pallium development GO:0021543 120 0.978
prostate gland development GO:0030850 48 0.977
regulation of lateral mesodermal cell fate specification GO:0048378 2 0.977
regulation of intracellular transport GO:0032386 159 0.977
Human Rat
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.977
regulation of endodermal cell fate specification GO:0042663 2 0.977
Zebrafish
regulation of ureteric bud formation GO:0072106 3 0.977
axial mesodermal cell differentiation GO:0048321 1 0.977
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.977
forebrain radial glial cell differentiation GO:0021861 4 0.977
response to fibroblast growth factor GO:0071774 47 0.977
axial mesoderm formation GO:0048320 3 0.977
establishment of planar polarity involved in neural tube closure GO:0090177 15 0.976
negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis GO:2000164 1 0.976
negative regulation of embryonic development GO:0045992 22 0.976
regulation of planar cell polarity pathway involved in heart morphogenesis GO:2000159 1 0.976
cardiac atrium development GO:0003230 24 0.975
ureter morphogenesis GO:0072197 4 0.975
salivary gland morphogenesis GO:0007435 33 0.975
neural crest cell differentiation GO:0014033 54 0.974
septum primum development GO:0003284 4 0.974
regulation of wnt signaling pathway GO:0030111 123 0.974
Mouse
neural crest formation GO:0014029 2 0.974
hypophysis morphogenesis GO:0048850 3 0.974
diencephalon morphogenesis GO:0048852 6 0.973
regulation of cartilage development GO:0061035 44 0.973
negative regulation of gastrulation GO:2000542 3 0.973
Zebrafish
wnt signaling pathway involved in heart development GO:0003306 8 0.973
nephron epithelium morphogenesis GO:0072088 68 0.973
metanephric nephron development GO:0072210 34 0.973
Human
fibroblast growth factor receptor signaling pathway involved in mammary gland specification GO:0060595 2 0.973
mesonephric tubule morphogenesis GO:0072171 63 0.973
organ growth GO:0035265 117 0.972
Fly
regulation of cell adhesion mediated by integrin GO:0033628 13 0.972
positive regulation of neuroblast proliferation GO:0002052 19 0.972
regulation of branching involved in prostate gland morphogenesis GO:0060687 7 0.972
mesonephric duct morphogenesis GO:0072180 4 0.971
mammary placode formation GO:0060596 4 0.971
midbrain hindbrain boundary development GO:0030917 9 0.971
tube formation GO:0035148 140 0.971
trachea development GO:0060438 18 0.971
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.970
Mouse
lateral mesoderm development GO:0048368 13 0.970
positive regulation of branching involved in lung morphogenesis GO:0061047 4 0.970
multicellular organism growth GO:0035264 161 0.970
mammary gland bud formation GO:0060615 2 0.969
negative regulation of osteoblast differentiation GO:0045668 30 0.969
hair cycle GO:0042633 90 0.969
cardiac muscle tissue growth GO:0055017 37 0.969
branch elongation involved in salivary gland morphogenesis GO:0060667 2 0.967
cochlea morphogenesis GO:0090103 22 0.967
regulation of cardiac muscle cell proliferation GO:0060043 23 0.967
embryonic neurocranium morphogenesis GO:0048702 3 0.967
forelimb morphogenesis GO:0035136 40 0.966
myelination in peripheral nervous system GO:0022011 19 0.966
negative regulation of branching involved in ureteric bud morphogenesis GO:0090191 4 0.966
regulation of branching involved in ureteric bud morphogenesis GO:0090189 22 0.965
positive regulation of epithelial to mesenchymal transition GO:0010718 13 0.965
Mouse
endocrine system development GO:0035270 98 0.965
positive regulation of cell proliferation involved in heart morphogenesis GO:2000138 5 0.965
morphogenesis of a branching structure GO:0001763 203 0.965
forebrain neuron differentiation GO:0021879 52 0.965
regulation of fat cell differentiation GO:0045598 81 0.965
Mouse
central nervous system neuron differentiation GO:0021953 162 0.964
glomerulus development GO:0032835 40 0.964
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 18 0.964
Rat
muscle tissue development GO:0060537 308 0.964
gastrulation with mouth forming second GO:0001702 29 0.963
Mouse
negative regulation of cell development GO:0010721 169 0.963
Rat
epithelial cell differentiation involved in kidney development GO:0035850 23 0.963
paraxial mesoderm morphogenesis GO:0048340 10 0.962
negative regulation of planar cell polarity pathway involved in neural tube closure GO:2000168 1 0.962
central nervous system vasculogenesis GO:0022009 3 0.962
t cell differentiation GO:0030217 174 0.962
Human
regulation of myoblast differentiation GO:0045661 29 0.962
Human Mouse
negative regulation of immature t cell proliferation GO:0033087 3 0.962
Human
cell proliferation involved in metanephros development GO:0072203 9 0.961
dorsal ventral neural tube patterning GO:0021904 28 0.961
glomerular endothelium development GO:0072011 2 0.961
male gamete generation GO:0048232 285 0.960
retinal bipolar neuron differentiation GO:0060040 5 0.960
epiblast cell extraembryonic ectoderm cell signaling involved in anterior posterior axis specification GO:0060802 1 0.960
regulation of transcription from rna polymerase ii promoter by glucose GO:0000430 3 0.959
hindbrain development GO:0030902 128 0.959
morphogenesis of a polarized epithelium GO:0001738 37 0.959
inner ear morphogenesis GO:0042472 101 0.958
prostate gland epithelium morphogenesis GO:0060740 31 0.958
negative regulation of glial cell proliferation GO:0060253 4 0.958
cilium morphogenesis GO:0060271 102 0.958
erythrocyte differentiation GO:0030218 88 0.958
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development GO:0060528 4 0.958
endocardial cushion development GO:0003197 26 0.957
Mouse
positive regulation of cartilage development GO:0061036 18 0.957
Human Mouse
cardiac ventricle morphogenesis GO:0003208 50 0.957
blastocyst formation GO:0001825 33 0.956
otic vesicle development GO:0071599 14 0.956
positive regulation of endothelial cell migration GO:0010595 12 0.956
Human
pattern specification involved in metanephros development GO:0072268 4 0.955
maternal placenta development GO:0001893 20 0.954
axonogenesis GO:0007409 274 0.954
neuroblast proliferation GO:0007405 49 0.954
positive regulation of angiogenesis GO:0045766 46 0.953
cerebral cortex neuron differentiation GO:0021895 19 0.953
paraxial mesodermal cell fate commitment GO:0048343 2 0.953
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.952
mitral valve morphogenesis GO:0003183 4 0.952
ascending aorta morphogenesis GO:0035910 3 0.952
cell proliferation in forebrain GO:0021846 30 0.952
somite rostral caudal axis specification GO:0032525 13 0.952
Mouse
positive regulation of cardiac muscle tissue growth GO:0055023 15 0.951
cell adhesion GO:0007155 329 0.951
lung lobe morphogenesis GO:0060463 9 0.950
neuron migration GO:0001764 122 0.950
forebrain neuroblast division GO:0021873 9 0.950
somatic stem cell maintenance GO:0035019 47 0.950
striated muscle cell proliferation GO:0014855 39 0.949
regulation of cardiac chamber morphogenesis GO:1901219 2 0.949
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.949
muscle cell development GO:0055001 133 0.949
Human Mouse
regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:2000161 1 0.949
regulation of angiogenesis GO:0045765 81 0.949
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.948
Human Mouse Fly
regulation of mesenchymal cell proliferation GO:0010464 37 0.947
Human
negative regulation of prostatic bud formation GO:0060686 4 0.947
regulation of epithelial to mesenchymal transition GO:0010717 22 0.946
Mouse
determination of left right symmetry GO:0007368 80 0.945
Zebrafish
atrioventricular bundle cell differentiation GO:0003167 1 0.945
endodermal cell differentiation GO:0035987 14 0.945
Zebrafish
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.944
regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:2000150 1 0.943
inhibition of neuroepithelial cell differentiation GO:0002085 2 0.943
muscle cell fate specification GO:0042694 1 0.943
cardiac right ventricle formation GO:0003219 3 0.943
granulosa cell differentiation GO:0060014 1 0.942
cerebral cortex tangential migration GO:0021800 7 0.942
molting cycle GO:0042303 90 0.942
spinal cord motor neuron differentiation GO:0021522 35 0.942
renal capsule formation GO:0072129 1 0.942
neural crest cell fate commitment GO:0014034 1 0.942
embryonic olfactory bulb interneuron precursor migration GO:0021831 2 0.941
embryonic nail plate morphogenesis GO:0035880 3 0.941
positive regulation of smoothened signaling pathway GO:0045880 23 0.941

Bmp4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
heart disease DOID:114 0 0.985
disease of anatomical entity DOID:7 0 0.985
Human
cardiovascular system disease DOID:1287 0 0.985
sensory system disease DOID:0050155 0 0.962
Human
eye and adnexa disease DOID:1492 0 0.962
Human
nervous system disease DOID:863 0 0.962
Human