IMP

Process View

Mus musculus

9 genes annotated in mouse

branching involved in labyrinthine layer morphogenesis

The process in which the branches of the fetal placental villi are generated and organized. The villous part of the placenta is called the labyrinth layer.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "branching involved in labyrinthine layer morphogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "branching involved in labyrinthine layer morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
Fgfr2	fibroblast growth factor receptor 2	0.999
Gli3	GLI-Kruppel family member GLI3	0.992
Shh	sonic hedgehog	0.980
Bmp4	bone morphogenetic protein 4	0.979
Sox9	SRY-box containing gene 9	0.975
Foxc1	forkhead box C1	0.920
Lepr	leptin receptor	0.839
Prrx1	paired related homeobox 1	0.826
Gli2	GLI-Kruppel family member GLI2	0.747
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.680
Fgfr1	fibroblast growth factor receptor 1	0.616	Mouse
Bmp7	bone morphogenetic protein 7	0.608
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.512
Smo	smoothened homolog (Drosophila)	0.507
Eya1	eyes absent 1 homolog (Drosophila)	0.421
Tgfb2	transforming growth factor, beta 2	0.396
Rarg	retinoic acid receptor, gamma	0.388
Fgfr3	fibroblast growth factor receptor 3	0.359	Mouse
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.357
Rarb	retinoic acid receptor, beta	0.323
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.295
Msx1	homeobox, msh-like 1	0.294
Vegfa	vascular endothelial growth factor A	0.293
Gopc	golgi associated PDZ and coiled-coil motif containing	0.286
Wnt5a	wingless-related MMTV integration site 5A	0.243
Prrx2	paired related homeobox 2	0.231
Vangl2	vang-like 2 (van gogh, Drosophila)	0.212
Acvr1	activin A receptor, type 1	0.201
Ednra	endothelin receptor type A	0.201
Pbx1	pre B-cell leukemia transcription factor 1	0.182
Hand2	heart and neural crest derivatives expressed transcript 2	0.165
Rara	retinoic acid receptor, alpha	0.163
Foxc2	forkhead box C2	0.162
Cd247	CD247 antigen	0.154
Dlx5	distal-less homeobox 5	0.124
Tbx1	T-box 1	0.124
Ctnnb1	catenin (cadherin associated protein), beta 1	0.117
Fgf8	fibroblast growth factor 8	0.117
Egfr	epidermal growth factor receptor	0.104
Zeb1	zinc finger E-box binding homeobox 1	0.102
Smad3	MAD homolog 3 (Drosophila)	0.087
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.076
Bcl2	B-cell leukemia/lymphoma 2	0.071
Bmp2	bone morphogenetic protein 2	0.070
Jag1	jagged 1	0.070
Rxra	retinoid X receptor alpha	0.064
Jak2	Janus kinase 2	0.063
Pax3	paired box gene 3	0.062
Tgfbr2	transforming growth factor, beta receptor II	0.062
Tcfap2a	transcription factor AP-2, alpha	0.058
Pax2	paired box gene 2	0.049
Gpc3	glypican 3	0.048
Chrd	chordin	0.048
Runx2	runt related transcription factor 2	0.047
Ptch1	patched homolog 1	0.046
Fgf10	fibroblast growth factor 10	0.045
Sox4	SRY-box containing gene 4	0.043
Pax8	paired box gene 8	0.041
Fzd7	frizzled homolog 7 (Drosophila)	0.040	Mouse
Hoxb3	homeobox B3	0.040
Twist2	twist homolog 2 (Drosophila)	0.038
Pitx2	paired-like homeodomain transcription factor 2	0.032
Gab2	growth factor receptor bound protein 2-associated protein 2	0.031
Msx2	homeobox, msh-like 2	0.030
Bmp5	bone morphogenetic protein 5	0.030
Fzd2	frizzled homolog 2 (Drosophila)	0.028	Mouse
Cish	cytokine inducible SH2-containing protein	0.027	Mouse
Hoxa3	homeobox A3	0.023
Meox2	mesenchyme homeobox 2	0.023
Ifng	interferon gamma	0.023
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.023
Il6st	interleukin 6 signal transducer	0.022
Mrc2	mannose receptor, C type 2	0.022
Wfdc2	WAP four-disulfide core domain 2	0.021
D930020E02Rik	RIKEN cDNA D930020E02 gene	0.021
Stat5a	signal transducer and activator of transcription 5A	0.021
Pax9	paired box gene 9	0.020
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.020
Tcf21	transcription factor 21	0.020
Ptk7	PTK7 protein tyrosine kinase 7	0.020
Hoxa5	homeobox A5	0.020
Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.020
Hes1	hairy and enhancer of split 1 (Drosophila)	0.019
Trp53	transformation related protein 53	0.019
Il10	interleukin 10	0.019
Map4k1	mitogen-activated protein kinase kinase kinase kinase 1	0.019
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.018
Fgfrl1	fibroblast growth factor receptor-like 1	0.018
Apc	adenomatosis polyposis coli	0.017
Dlg4	discs, large homolog 4 (Drosophila)	0.017
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.017
Smad6	MAD homolog 6 (Drosophila)	0.017
Hoxa11	homeobox A11	0.017
Hoxa2	homeobox A2	0.017
Sfrp2	secreted frizzled-related protein 2	0.016
Alx1	ALX homeobox 1	0.016
Fzd8	frizzled homolog 8 (Drosophila)	0.016	Mouse
Wnt11	wingless-related MMTV integration site 11	0.016
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.016
Hand1	heart and neural crest derivatives expressed transcript 1	0.015
Ece1	endothelin converting enzyme 1	0.015
Lrp6	low density lipoprotein receptor-related protein 6	0.015
Wnt4	wingless-related MMTV integration site 4	0.015
Zap70	zeta-chain (TCR) associated protein kinase	0.014
Col11a1	collagen, type XI, alpha 1	0.014
Sox2	SRY-box containing gene 2	0.014
Ret	ret proto-oncogene	0.014
Fbln1	fibulin 1	0.014
Sox11	SRY-box containing gene 11	0.014
Tnf	tumor necrosis factor	0.014
Vhl	von Hippel-Lindau tumor suppressor	0.013
Stat3	signal transducer and activator of transcription 3	0.013
Bmper	BMP-binding endothelial regulator	0.013
Tbx3	T-box 3	0.013
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.012
Hoxa10	homeobox A10	0.012
Efnb2	ephrin B2	0.012
Dll1	delta-like 1 (Drosophila)	0.012
Cul5	cullin 5	0.011
Nos2	nitric oxide synthase 2, inducible	0.011
Nf1	neurofibromatosis 1	0.011
Wnt3a	wingless-related MMTV integration site 3A	0.011
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.011
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.011
Pthlh	parathyroid hormone-like peptide	0.011
Foxa2	forkhead box A2	0.011
Nlrp3	NLR family, pyrin domain containing 3	0.011
Hoxa9	homeobox A9	0.011
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.010	Mouse
Dlg1	discs, large homolog 1 (Drosophila)	0.010
Kl	klotho	0.010