Mus musculus

119 known processes

C5ar1

complement component 5a receptor 1

(Aliases: C5aR,Cd88,D7Msu1,C5r1)

C5ar1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
defense response to gram positive bacterium GO:0050830 50 0.897
leukocyte chemotaxis GO:0030595 69 0.855
cytokine production GO:0001816 319 0.747
cell chemotaxis GO:0060326 81 0.737
keratinocyte migration GO:0051546 3 0.720
Mouse
inflammatory response GO:0006954 244 0.690
neutrophil mediated killing of gram positive bacterium GO:0070946 2 0.690
defense response to other organism GO:0098542 197 0.632
regulation of cytokine production GO:0001817 266 0.613
leukocyte migration GO:0050900 124 0.610
regulation of secretion GO:0051046 274 0.601
positive regulation of cell migration GO:0030335 109 0.592
myeloid leukocyte mediated immunity GO:0002444 42 0.578
regulation of inflammatory response GO:0050727 147 0.575
mapk cascade GO:0000165 281 0.567
Human
positive regulation of defense response GO:0031349 124 0.520
regulation of defense response GO:0031347 233 0.517
regulation of cell motility GO:2000145 236 0.515
positive regulation of cytokine production GO:0001819 174 0.508
positive regulation of neutrophil chemotaxis GO:0090023 12 0.475
granulocyte chemotaxis GO:0071621 39 0.468
positive regulation of mapk cascade GO:0043410 170 0.468
Human
fat cell differentiation GO:0045444 160 0.458
Mouse
mast cell activation involved in immune response GO:0002279 20 0.458
regulation of cell migration GO:0030334 219 0.451
myeloid leukocyte migration GO:0097529 57 0.412
extrinsic apoptotic signaling pathway GO:0097191 126 0.409
positive regulation of monocyte chemotaxis GO:0090026 2 0.406
regulation of response to wounding GO:1903034 189 0.403
myeloid cell activation involved in immune response GO:0002275 34 0.401
neutrophil mediated immunity GO:0002446 19 0.390
leukocyte activation involved in immune response GO:0002366 126 0.389
regulation of map kinase activity GO:0043405 120 0.381
regulation of cell activation GO:0050865 289 0.378
neutrophil chemotaxis GO:0030593 36 0.373
membrane organization GO:0061024 245 0.372
regulation of mapk cascade GO:0043408 248 0.365
Human
regulated secretory pathway GO:0045055 32 0.355
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.355
regulation of leukocyte mediated immunity GO:0002703 104 0.347
apoptotic signaling pathway GO:0097190 306 0.340
positive regulation of inflammatory response GO:0050729 47 0.337
blood vessel morphogenesis GO:0048514 285 0.336
defense response to bacterium GO:0042742 119 0.327
regulation of chemokine production GO:0032642 30 0.320
positive regulation of secretion by cell GO:1903532 114 0.315
carbohydrate derivative biosynthetic process GO:1901137 183 0.314
regulation of protein secretion GO:0050708 82 0.304
signal transduction in absence of ligand GO:0038034 55 0.301
regulation of cellular response to stress GO:0080135 159 0.295
regulation of fat cell differentiation GO:0045598 81 0.295
Mouse
neutrophil mediated killing of symbiont cell GO:0070943 8 0.292
lysosome localization GO:0032418 20 0.283
response to molecule of bacterial origin GO:0002237 143 0.280
positive regulation of macrophage chemotaxis GO:0010759 5 0.279
regulation of mast cell degranulation GO:0043304 16 0.276
positive regulation of protein modification process GO:0031401 299 0.272
second messenger mediated signaling GO:0019932 73 0.261
Mouse
neutrophil migration GO:1990266 37 0.259
regulation of innate immune response GO:0045088 91 0.258
negative regulation of cell migration GO:0030336 59 0.248
mast cell degranulation GO:0043303 19 0.234
rho protein signal transduction GO:0007266 32 0.231
granulocyte migration GO:0097530 43 0.229
chemotaxis GO:0006935 247 0.227
divalent inorganic cation transport GO:0072511 178 0.217
response to organonitrogen compound GO:0010243 246 0.216
positive regulation of cholesterol storage GO:0010886 3 0.208
positive regulation of transferase activity GO:0051347 167 0.203
adaptive immune response GO:0002250 155 0.202
regulation of homeostatic process GO:0032844 182 0.201
regulation of establishment of protein localization GO:0070201 181 0.200
myeloid leukocyte activation GO:0002274 83 0.200
cellular lipid metabolic process GO:0044255 323 0.198
antibacterial peptide secretion GO:0002779 1 0.198
positive regulation of cell activation GO:0050867 158 0.196
regulation of endocytosis GO:0030100 69 0.196
stress activated protein kinase signaling cascade GO:0031098 81 0.194
disruption by host of symbiont cells GO:0051852 11 0.191
angiogenesis GO:0001525 201 0.188
positive regulation of secretion GO:0051047 130 0.187
anatomical structure homeostasis GO:0060249 145 0.187
cellular metal ion homeostasis GO:0006875 151 0.184
organelle localization GO:0051640 179 0.182
interaction with symbiont GO:0051702 14 0.179
erk1 and erk2 cascade GO:0070371 77 0.175
Human
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.175
regulation of monocyte chemotaxis GO:0090025 3 0.173
regulation of vesicle mediated transport GO:0060627 139 0.172
positive regulation of homeostatic process GO:0032846 64 0.169
extracellular matrix organization GO:0030198 147 0.168
positive regulation of map kinase activity GO:0043406 84 0.168
positive regulation of cytokine biosynthetic process GO:0042108 40 0.166
negative regulation of intracellular signal transduction GO:1902532 167 0.165
antibacterial humoral response GO:0019731 8 0.165
positive regulation of cell motility GO:2000147 116 0.161
ribose phosphate metabolic process GO:0019693 291 0.160
response to peptide hormone GO:0043434 127 0.159
immune effector process GO:0002252 321 0.158
regulation of protein localization GO:0032880 231 0.158
negative regulation of immune system process GO:0002683 209 0.156
positive regulation of t cell extravasation GO:2000409 2 0.156
multicellular organismal homeostasis GO:0048871 164 0.155
regulation of tissue remodeling GO:0034103 38 0.155
regulation of exocytosis GO:0017157 61 0.152
leukocyte mediated immunity GO:0002443 174 0.150
regulation of apoptotic signaling pathway GO:2001233 197 0.149
regulation of secretion by cell GO:1903530 249 0.147
regulation of protein serine threonine kinase activity GO:0071900 157 0.147
activation of mapk activity GO:0000187 59 0.145
positive regulation of neutrophil migration GO:1902624 12 0.145
small gtpase mediated signal transduction GO:0007264 97 0.144
positive regulation of protein phosphorylation GO:0001934 242 0.144
cytokine secretion GO:0050663 72 0.143
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.143
Human
regulation of mast cell activation GO:0033003 21 0.139
t helper 17 cell chemotaxis GO:0035705 1 0.136
blood circulation GO:0008015 195 0.134
nitrogen compound transport GO:0071705 271 0.134
endocytosis GO:0006897 168 0.133
defense response to fungus GO:0050832 12 0.133
regulation of tumor necrosis factor production GO:0032680 49 0.130
modification of morphology or physiology of other organism GO:0035821 18 0.130
transmission of nerve impulse GO:0019226 76 0.130
lymphocyte mediated immunity GO:0002449 139 0.128
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.128
positive regulation of chemokine secretion GO:0090197 4 0.128
reactive oxygen species biosynthetic process GO:1903409 8 0.127
exocytosis GO:0006887 121 0.127
positive regulation of immune effector process GO:0002699 107 0.127
positive regulation of kinase activity GO:0033674 155 0.127
positive regulation of eosinophil migration GO:2000418 2 0.124
regulation of lymphocyte activation GO:0051249 240 0.124
regulation of chemokine secretion GO:0090196 4 0.124
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation GO:2000721 2 0.124
ras protein signal transduction GO:0007265 77 0.123
regulation of phospholipase c activity GO:1900274 3 0.123
circulatory system process GO:0003013 197 0.123
positive regulation of acute inflammatory response GO:0002675 16 0.121
myeloid cell differentiation GO:0030099 233 0.121
nucleotide metabolic process GO:0009117 332 0.118
interleukin 12 secretion GO:0072610 3 0.118
regulation of leukocyte degranulation GO:0043300 20 0.117
positive regulation of tumor necrosis factor biosynthetic process GO:0042535 8 0.116
muscle cell differentiation GO:0042692 261 0.115
negative regulation of t helper 1 cell differentiation GO:0045626 3 0.115
regulation of mast cell activation involved in immune response GO:0033006 17 0.113
regulation of macrophage chemotaxis GO:0010758 8 0.113
positive regulation of dendritic cell dendrite assembly GO:2000549 1 0.113
protein kinase b signaling GO:0043491 74 0.113
leukocyte migration involved in inflammatory response GO:0002523 7 0.112
jnk cascade GO:0007254 72 0.111
positive regulation of stress activated mapk cascade GO:0032874 48 0.111
cellular response to cytokine stimulus GO:0071345 189 0.111
purine containing compound metabolic process GO:0072521 311 0.109
cell activation involved in immune response GO:0002263 126 0.108
organonitrogen compound biosynthetic process GO:1901566 192 0.107
positive regulation of granulocyte chemotaxis GO:0071624 12 0.107
regulation of bone resorption GO:0045124 24 0.106
regulation of protein transport GO:0051223 163 0.106
response to lipopolysaccharide GO:0032496 128 0.106
regulation of protein kinase activity GO:0045859 232 0.104
regulation of blood pressure GO:0008217 93 0.104
killing of cells of other organism GO:0031640 13 0.104
oxidation reduction process GO:0055114 342 0.104
wound healing GO:0042060 157 0.104
negative regulation of cell motility GO:2000146 61 0.103
t cell activation GO:0042110 289 0.103
production of molecular mediator involved in inflammatory response GO:0002532 21 0.103
ameboidal type cell migration GO:0001667 128 0.102
Mouse
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.100
Mouse
smooth muscle contraction GO:0006939 44 0.099
mast cell mediated immunity GO:0002448 20 0.098
macrophage chemotaxis GO:0048246 14 0.097
regulation of cytokine biosynthetic process GO:0042035 59 0.096
glycoprotein metabolic process GO:0009100 116 0.095
protein catabolic process GO:0030163 221 0.094
positive regulation of angiogenesis GO:0045766 46 0.094
leukocyte degranulation GO:0043299 27 0.094
organic hydroxy compound transport GO:0015850 93 0.093
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.092
calcium mediated signaling GO:0019722 46 0.091
Mouse
thymocyte migration GO:0072679 2 0.089
acute inflammatory response GO:0002526 41 0.089
glycoprotein biosynthetic process GO:0009101 89 0.088
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.088
tissue homeostasis GO:0001894 115 0.088
killing by host of symbiont cells GO:0051873 11 0.088
reactive oxygen species metabolic process GO:0072593 84 0.088
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.088
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.087
bone remodeling GO:0046849 53 0.087
positive regulation of response to wounding GO:1903036 66 0.086
lipid biosynthetic process GO:0008610 179 0.086
positive regulation of monocyte extravasation GO:2000439 1 0.085
regulation of proteolysis GO:0030162 164 0.085
killing of cells in other organism involved in symbiotic interaction GO:0051883 13 0.085
microglia development GO:0014005 2 0.084
kidney development GO:0001822 213 0.084
cell cell adhesion GO:0098609 41 0.083
protein localization to organelle GO:0033365 185 0.083
amino sugar catabolic process GO:0046348 1 0.083
regulation of angiogenesis GO:0045765 81 0.083
antimicrobial peptide biosynthetic process GO:0002777 2 0.082
response to oxidative stress GO:0006979 123 0.082
fatty acid metabolic process GO:0006631 121 0.082
cell killing GO:0001906 67 0.081
amine metabolic process GO:0009308 45 0.081
leukotriene metabolic process GO:0006691 7 0.081
positive regulation of protein secretion GO:0050714 52 0.081
t cell migration GO:0072678 19 0.081
stress activated mapk cascade GO:0051403 80 0.080
negative regulation of cytokine production GO:0001818 84 0.080
Mouse
regulation of hemostasis GO:1900046 28 0.079
positive regulation of apoptotic process GO:0043065 217 0.079
regulation of natural killer cell chemotaxis GO:2000501 1 0.079
macrophage differentiation GO:0030225 20 0.078
regulation of system process GO:0044057 200 0.078
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 20 0.078
Mouse
positive regulation of coagulation GO:0050820 13 0.078
positive regulation of protein kinase activity GO:0045860 144 0.077
positive regulation of macrophage activation GO:0043032 10 0.077
blood coagulation GO:0007596 76 0.076
nucleobase containing small molecule metabolic process GO:0055086 352 0.076
brown fat cell differentiation GO:0050873 36 0.075
positive regulation of phagocytosis GO:0050766 26 0.074
activation of immune response GO:0002253 138 0.072
Human
negative regulation of macrophage chemotaxis GO:0010760 1 0.072
regulation of macrophage activation GO:0043030 17 0.072
regulation of blood coagulation GO:0030193 28 0.071
negative regulation of ras protein signal transduction GO:0046580 18 0.071
regulation of t cell costimulation GO:2000523 2 0.071
maintenance of location GO:0051235 89 0.070
purine nucleotide metabolic process GO:0006163 302 0.070
morphogenesis of a branching epithelium GO:0061138 193 0.070
regulation of vasculature development GO:1901342 88 0.069
lipid transport GO:0006869 98 0.069
positive regulation of dendritic cell chemotaxis GO:2000510 1 0.068
regulation of type 2 immune response GO:0002828 18 0.068
cell adhesion GO:0007155 329 0.068
positive regulation of immune complex clearance by monocytes and macrophages GO:0090265 2 0.068
germ cell development GO:0007281 185 0.067
negative regulation of behavior GO:0048521 14 0.067
ribonucleotide metabolic process GO:0009259 291 0.067
positive regulation of chemotaxis GO:0050921 38 0.067
b cell chemotaxis GO:0035754 3 0.067
innate immune response GO:0045087 157 0.067
regulation of regulated secretory pathway GO:1903305 20 0.066
defense response to virus GO:0051607 68 0.066
eosinophil mediated immunity GO:0002447 1 0.066
positive regulation of bone resorption GO:0045780 13 0.066
lipid localization GO:0010876 126 0.064
regulation of protein kinase b signaling GO:0051896 56 0.064
regulation of kinase activity GO:0043549 249 0.064
purine ribonucleoside metabolic process GO:0046128 241 0.064
positive regulation of leukocyte mediated immunity GO:0002705 70 0.063
ribonucleoside triphosphate catabolic process GO:0009203 199 0.063
positive regulation of phospholipase c activity GO:0010863 2 0.063
epithelial tube morphogenesis GO:0060562 303 0.063
regulation of t helper 1 type immune response GO:0002825 17 0.063
cellular calcium ion homeostasis GO:0006874 119 0.062
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.061
response to extracellular stimulus GO:0009991 127 0.061
cell maturation GO:0048469 127 0.061
regulation of cell adhesion GO:0030155 154 0.061
synapse assembly GO:0007416 56 0.061
neutrophil mediated cytotoxicity GO:0070942 8 0.060
regulation of blood vessel size GO:0050880 56 0.060
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.060
nucleoside metabolic process GO:0009116 246 0.060
phagocytosis GO:0006909 66 0.060
lymphocyte proliferation GO:0046651 164 0.060
interleukin 8 production GO:0032637 4 0.060
inflammatory response to wounding GO:0090594 4 0.059
cellular ketone metabolic process GO:0042180 84 0.059
myeloid leukocyte differentiation GO:0002573 119 0.059
wound healing involved in inflammatory response GO:0002246 4 0.058
positive regulation of thymocyte migration GO:2000412 2 0.058
positive regulation of cytokine secretion GO:0050715 41 0.058
cognition GO:0050890 149 0.058
cellular response to organonitrogen compound GO:0071417 145 0.058
positive regulation of fat cell differentiation GO:0045600 32 0.058
Mouse
extracellular structure organization GO:0043062 148 0.057
cellular amide metabolic process GO:0043603 58 0.057
neutrophil mediated killing of fungus GO:0070947 3 0.057
cytokine metabolic process GO:0042107 71 0.057
positive regulation of leukocyte proliferation GO:0070665 73 0.057
negative regulation of inflammatory response GO:0050728 61 0.057
tissue remodeling GO:0048771 102 0.057
peptidyl amino acid modification GO:0018193 336 0.056
activation of jun kinase activity GO:0007257 15 0.056
antimicrobial peptide production GO:0002775 2 0.056
dendritic spine maintenance GO:0097062 4 0.056
regulation of lipid transport GO:0032368 36 0.055
response to drug GO:0042493 75 0.055
unsaturated fatty acid metabolic process GO:0033559 31 0.055
eosinophil migration GO:0072677 3 0.055
positive regulation of syncytium formation by plasma membrane fusion GO:0060143 17 0.055
cellular homeostasis GO:0019725 240 0.054
regulation of bone remodeling GO:0046850 28 0.054
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.054
positive regulation of endocytosis GO:0045807 42 0.054
nucleoside phosphate metabolic process GO:0006753 338 0.054
negative regulation of vasculature development GO:1901343 26 0.054
positive regulation of jnk cascade GO:0046330 46 0.054
regulation of myeloid leukocyte mediated immunity GO:0002886 25 0.054
positive regulation of immunological synapse formation GO:2000522 1 0.054
alpha beta t cell activation GO:0046631 91 0.054
positive regulation of behavior GO:0048520 40 0.054
positive regulation of mast cell degranulation GO:0043306 10 0.053
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.053
positive regulation of natural killer cell chemotaxis GO:2000503 1 0.053
serotonin secretion involved in inflammatory response GO:0002442 4 0.052
polysaccharide metabolic process GO:0005976 39 0.052
neuron migration GO:0001764 122 0.052
positive regulation of exocytosis GO:0045921 20 0.052
production of molecular mediator of immune response GO:0002440 103 0.051
regulation of phagocytosis GO:0050764 33 0.051
single organism cell adhesion GO:0098602 156 0.051
regulation of transferase activity GO:0051338 263 0.051
cellular amine metabolic process GO:0044106 44 0.050
regulation of eosinophil migration GO:2000416 2 0.050
mast cell activation GO:0045576 27 0.050
alcohol metabolic process GO:0006066 116 0.050
immune response activating signal transduction GO:0002757 116 0.050
Human
fc epsilon receptor signaling pathway GO:0038095 3 0.050
regulation of systemic arterial blood pressure GO:0003073 61 0.050
helper t cell chemotaxis GO:0035704 1 0.050
cellular response to peptide hormone stimulus GO:0071375 92 0.049
fatty acid derivative biosynthetic process GO:1901570 15 0.049
receptor mediated endocytosis GO:0006898 51 0.049
regulation of intracellular transport GO:0032386 159 0.049
biomineral tissue development GO:0031214 64 0.049
peptide metabolic process GO:0006518 46 0.048
substrate adhesion dependent cell spreading GO:0034446 30 0.048
immunoglobulin mediated immune response GO:0016064 69 0.048
response to nutrient levels GO:0031667 109 0.048
amide transport GO:0042886 138 0.048
positive regulation of myeloid leukocyte mediated immunity GO:0002888 14 0.048
eosinophil activation GO:0043307 1 0.048
organic acid biosynthetic process GO:0016053 86 0.048
carbohydrate metabolic process GO:0005975 230 0.047
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.047
regulation of jun kinase activity GO:0043506 40 0.046
fatty acid derivative metabolic process GO:1901568 33 0.046
positive regulation of lymphocyte activation GO:0051251 140 0.046
positive regulation of chemokine production GO:0032722 22 0.045
regulation of b cell mediated immunity GO:0002712 37 0.045
connective tissue development GO:0061448 179 0.045
positive regulation of programmed cell death GO:0043068 218 0.045
regulation of myeloid cell differentiation GO:0045637 96 0.045
action potential GO:0001508 78 0.045
aromatic compound catabolic process GO:0019439 286 0.045
leukocyte cell cell adhesion GO:0007159 14 0.044
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.044
response to peptide GO:1901652 136 0.044
regulation of thymocyte migration GO:2000410 2 0.044
positive regulation of leukocyte differentiation GO:1902107 86 0.044
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.044
regulation of purine nucleotide metabolic process GO:1900542 169 0.043
negative regulation of apoptotic signaling pathway GO:2001234 104 0.043
tumor necrosis factor production GO:0032640 50 0.043
icosanoid metabolic process GO:0006690 33 0.043
sequestering of metal ion GO:0051238 19 0.043
regulation of stress activated mapk cascade GO:0032872 69 0.043
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.043
cell growth GO:0016049 130 0.043
negative regulation of muscle contraction GO:0045932 12 0.042
protein secretion GO:0009306 111 0.042
leukocyte proliferation GO:0070661 172 0.042
cellular divalent inorganic cation homeostasis GO:0072503 127 0.042
response to decreased oxygen levels GO:0036293 59 0.042
positive regulation of g protein coupled receptor protein signaling pathway GO:0045745 10 0.041
Mouse
eosinophil activation involved in immune response GO:0002278 1 0.041
inflammatory response to antigenic stimulus GO:0002437 30 0.041
cytosolic calcium ion transport GO:0060401 48 0.041
growth plate cartilage development GO:0003417 14 0.041
macromolecule catabolic process GO:0009057 281 0.041
positive regulation of dna biosynthetic process GO:2000573 4 0.041
posttranscriptional regulation of gene expression GO:0010608 155 0.040
mature dendritic cell differentiation GO:0097029 3 0.040
cellular response to biotic stimulus GO:0071216 92 0.040
regulation of myotube differentiation GO:0010830 62 0.040
macrophage activation GO:0042116 27 0.040
regulation of erk1 and erk2 cascade GO:0070372 71 0.040
Human
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.040
Human
cholesterol storage GO:0010878 4 0.040
protein targeting GO:0006605 143 0.040
skeletal system morphogenesis GO:0048705 203 0.040
monoamine transport GO:0015844 33 0.040
axonogenesis GO:0007409 274 0.039
regulation of vascular endothelial growth factor production GO:0010574 13 0.039
bone mineralization GO:0030282 54 0.039
negative regulation of response to wounding GO:1903035 77 0.039
regulation of immunoglobulin mediated immune response GO:0002889 37 0.039
epithelial cell migration GO:0010631 63 0.039
Mouse
hypersensitivity GO:0002524 10 0.038
t helper 1 cell differentiation GO:0045063 13 0.038
coagulation GO:0050817 78 0.038
regulation of t helper 2 cell cytokine production GO:2000551 3 0.038
urogenital system development GO:0001655 261 0.038
cellular ion homeostasis GO:0006873 165 0.038
negative regulation of cellular protein metabolic process GO:0032269 247 0.038
regulation of jnk cascade GO:0046328 62 0.038
negative regulation of serotonin secretion GO:0014063 2 0.037
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.037
positive regulation of granulocyte macrophage colony stimulating factor biosynthetic process GO:0045425 2 0.037
regulation of neutrophil chemotaxis GO:0090022 14 0.037
regulation of lymphocyte proliferation GO:0050670 117 0.037
regulation of plasma lipoprotein particle levels GO:0097006 23 0.037
calcium ion homeostasis GO:0055074 127 0.037
bone development GO:0060348 120 0.037
regulation of hormone levels GO:0010817 211 0.037
activation of innate immune response GO:0002218 56 0.037
negative regulation of protein metabolic process GO:0051248 282 0.037
cation transport GO:0006812 399 0.037
skeletal system development GO:0001501 356 0.037
positive regulation of tumor necrosis factor production GO:0032760 30 0.037
activation of mapk activity involved in innate immune response GO:0035419 2 0.037
antibacterial peptide biosynthetic process GO:0002780 2 0.036
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.036
leukocyte differentiation GO:0002521 342 0.036
positive regulation of cell projection organization GO:0031346 95 0.036
response to organic cyclic compound GO:0014070 198 0.036
synapse organization GO:0050808 125 0.036
immune response regulating signaling pathway GO:0002764 125 0.036
Human
ribonucleoside metabolic process GO:0009119 245 0.036
cytokine biosynthetic process GO:0042089 68 0.036
neutrophil mediated killing of bacterium GO:0070944 6 0.036
cellular response to peptide GO:1901653 92 0.036
regulation of cd4 positive alpha beta t cell proliferation GO:2000561 2 0.035
multi multicellular organism process GO:0044706 109 0.035
hematopoietic stem cell migration GO:0035701 1 0.035
regulation of acute inflammatory response GO:0002673 27 0.035
cytokine mediated signaling pathway GO:0019221 115 0.035
multicellular organismal catabolic process GO:0044243 7 0.035
regulation of osteoclast differentiation GO:0045670 36 0.035
t helper 2 cell cytokine production GO:0035745 4 0.035
innate immune response activating signal transduction GO:0002758 50 0.035
peptide secretion GO:0002790 114 0.035
regulation of lymphocyte mediated immunity GO:0002706 84 0.035
pattern recognition receptor signaling pathway GO:0002221 47 0.034
single organismal cell cell adhesion GO:0016337 131 0.034
negative regulation of interleukin 13 secretion GO:2000666 1 0.034
glycosyl compound metabolic process GO:1901657 246 0.034
learning GO:0007612 98 0.034
regulation of cell projection assembly GO:0060491 38 0.034
protein processing GO:0016485 163 0.034
regulation of endopeptidase activity GO:0052548 89 0.034
developmental growth involved in morphogenesis GO:0060560 138 0.034
defense response to gram negative bacterium GO:0050829 28 0.034
positive regulation of innate immune response GO:0045089 80 0.034
sequestering of calcium ion GO:0051208 18 0.034
regulation of anatomical structure size GO:0090066 178 0.033
regulation of b cell chemotaxis GO:2000537 2 0.033
positive regulation of t cell costimulation GO:2000525 2 0.033
regulation of cytokine secretion GO:0050707 61 0.033
regulation of t cell extravasation GO:2000407 3 0.033
divalent metal ion transport GO:0070838 172 0.033
organophosphate catabolic process GO:0046434 232 0.033
sensory perception GO:0007600 245 0.033
negative regulation of secretion GO:0051048 61 0.033
purine containing compound catabolic process GO:0072523 213 0.033
phosphatidylinositol mediated signaling GO:0048015 41 0.033
regulation of calcium mediated signaling GO:0050848 19 0.033
b cell mediated immunity GO:0019724 71 0.033
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.032
negative regulation of rho protein signal transduction GO:0035024 7 0.032
positive regulation of calcium mediated signaling GO:0050850 15 0.032
glycosylation GO:0070085 62 0.032
vascular process in circulatory system GO:0003018 62 0.032
cellular response to oxidative stress GO:0034599 76 0.032
positive regulation of protein transport GO:0051222 93 0.032
eosinophil degranulation GO:0043308 1 0.032
ribonucleotide catabolic process GO:0009261 208 0.032
endochondral bone growth GO:0003416 19 0.032
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.032
release of sequestered calcium ion into cytosol GO:0051209 42 0.032
cellular amino acid metabolic process GO:0006520 103 0.032
detection of molecule of bacterial origin GO:0032490 2 0.032
regulation of alpha beta t cell activation GO:0046634 53 0.032
calcium ion transport into cytosol GO:0060402 48 0.032
intracellular protein transport GO:0006886 204 0.032
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526 1 0.031
regulation of dendritic cell chemotaxis GO:2000508 1 0.031
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.031
fatty acid biosynthetic process GO:0006633 41 0.031
cytokine production involved in immune response GO:0002367 34 0.031

C5ar1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
acquired immunodeficiency syndrome DOID:635 0 0.090
disease by infectious agent DOID:0050117 0 0.090
viral infectious disease DOID:934 0 0.090
human immunodeficiency virus infectious disease DOID:526 0 0.090
respiratory system disease DOID:1579 0 0.069
disease of anatomical entity DOID:7 0 0.069
disease of cellular proliferation DOID:14566 0 0.048
cancer DOID:162 0 0.033
organ system cancer DOID:0050686 0 0.033