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Click on a gene's description to view its network relationships with genes known to be involved in "regulation of mast cell activation involved in immune response"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of mast cell activation involved in immune response" (in gray)

Name	Description	Probability	Func Analog Organism
Inpp5d	inositol polyphosphate-5-phosphatase D	0.996
Cd247	CD247 antigen	0.995	Mouse
Grb2	growth factor receptor bound protein 2	0.993
Csf2rb2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)	0.983	Mouse
Ikzf1	IKAROS family zinc finger 1	0.965
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.959	Mouse
Mefv	Mediterranean fever	0.946
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.913
Ptprc	protein tyrosine phosphatase, receptor type, C	0.885
Lat	linker for activation of T cells	0.839
Tyrobp	TYRO protein tyrosine kinase binding protein	0.820
Tcra	T-cell receptor alpha chain	0.807
Dok1	docking protein 1	0.771
Il4	interleukin 4	0.770
Ptk2	PTK2 protein tyrosine kinase 2	0.760
Hcst	hematopoietic cell signal transducer	0.737
Cd22	CD22 antigen	0.697
Il2	interleukin 2	0.685
AF251705	cDNA sequence AF251705	0.617	Mouse
Csf1r	colony stimulating factor 1 receptor	0.580
Shc1	src homology 2 domain-containing transforming protein C1	0.526
Cbl	Casitas B-lineage lymphoma	0.521
Dok3	docking protein 3	0.386
Dok2	docking protein 2	0.360
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.355
Cd4	CD4 antigen	0.332
Il2rb	interleukin 2 receptor, beta chain	0.301
Cd40	CD40 antigen	0.294
Ccr6	chemokine (C-C motif) receptor 6	0.267
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.264
Hck	hemopoietic cell kinase	0.251	Mouse
Il2rg	interleukin 2 receptor, gamma chain	0.226
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.210
Cd180	CD180 antigen	0.186
Met	met proto-oncogene	0.172
Mb	myoglobin	0.167
Snai1	snail homolog 1 (Drosophila)	0.154
Cd79a	CD79A antigen (immunoglobulin-associated alpha)	0.143
Msr1	macrophage scavenger receptor 1	0.140
Grap2	GRB2-related adaptor protein 2	0.134
Nfam1	Nfat activating molecule with ITAM motif 1	0.126
C5ar1	complement component 5a receptor 1	0.113
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.106
Spib	Spi-B transcription factor (Spi-1/PU.1 related)	0.105
Il4ra	interleukin 4 receptor, alpha	0.102
Stat6	signal transducer and activator of transcription 6	0.101
Trpv1	transient receptor potential cation channel, subfamily V, member 1	0.099
Tbxas1	thromboxane A synthase 1, platelet	0.092
S1pr4	sphingosine-1-phosphate receptor 4	0.089
Cd68	CD68 antigen	0.086
Il13	interleukin 13	0.084
Hlx	H2.0-like homeobox	0.082
BC013712	cDNA sequence BC013712	0.078
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.074
Prkce	protein kinase C, epsilon	0.073
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.072
Ifng	interferon gamma	0.071
Il10ra	interleukin 10 receptor, alpha	0.071
Plcg1	phospholipase C, gamma 1	0.071
H2-DMb2	histocompatibility 2, class II, locus Mb2	0.071
Cmklr1	chemokine-like receptor 1	0.070
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.066
Jak2	Janus kinase 2	0.066
Cd300a	CD300A antigen	0.065
Fcgr3	Fc receptor, IgG, low affinity III	0.063	Mouse
Cd6	CD6 antigen	0.060
Irf5	interferon regulatory factor 5	0.059
Gpr35	G protein-coupled receptor 35	0.058
Lyl1	lymphoblastomic leukemia 1	0.056
Was	Wiskott-Aldrich syndrome homolog (human)	0.056
Pou2f2	POU domain, class 2, transcription factor 2	0.056
Lcn4	lipocalin 4	0.054
Ptgir	prostaglandin I receptor (IP)	0.053
Fes	feline sarcoma oncogene	0.053	Human Mouse
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.052
Cr2	complement receptor 2	0.052
Hcls1	hematopoietic cell specific Lyn substrate 1	0.049
Zap70	zeta-chain (TCR) associated protein kinase	0.049	Mouse
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.048
4632428N05Rik	RIKEN cDNA 4632428N05 gene	0.048
Blk	B lymphoid kinase	0.048	Mouse
Clec4n	C-type lectin domain family 4, member n	0.047
Cxcr3	chemokine (C-X-C motif) receptor 3	0.047
Plekho2	pleckstrin homology domain containing, family O member 2	0.046
Itgb3	integrin beta 3	0.045
Galnt6	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6	0.044
Trem3	triggering receptor expressed on myeloid cells 3	0.044
Fyn	Fyn proto-oncogene	0.044	Mouse
Plcg2	phospholipase C, gamma 2	0.043
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.043
Pik3cg	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.043
Cxcr5	chemokine (C-X-C motif) receptor 5	0.041
Sfpi1	SFFV proviral integration 1	0.040
Ager	advanced glycosylation end product-specific receptor	0.040
Tcirg1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3	0.039
Hrh1	histamine receptor H1	0.038
Rac2	RAS-related C3 botulinum substrate 2	0.038
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.037
Blnk	B-cell linker	0.036
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.036
Fcgr4	Fc receptor, IgG, low affinity IV	0.036
Pou2af1	POU domain, class 2, associating factor 1	0.036
Tcfec	transcription factor EC	0.036
Acvrl1	activin A receptor, type II-like 1	0.036
Lair1	leukocyte-associated Ig-like receptor 1	0.035
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.035
Igk	immunoglobulin kappa chain complex	0.035
Pilrb1	paired immunoglobin-like type 2 receptor beta 1	0.034
Cnr2	cannabinoid receptor 2 (macrophage)	0.034
Cd96	CD96 antigen	0.033
Ptpre	protein tyrosine phosphatase, receptor type, E	0.033
Ncr1	natural cytotoxicity triggering receptor 1	0.033
Hk3	hexokinase 3	0.033
Hmha1	histocompatibility (minor) HA-1	0.032
Hhex	hematopoietically expressed homeobox	0.032
Ubd	ubiquitin D	0.032
Itk	IL2-inducible T-cell kinase	0.031	Mouse
Fasl	Fas ligand (TNF superfamily, member 6)	0.031
Clec7a	C-type lectin domain family 7, member a	0.031
Ptpra	protein tyrosine phosphatase, receptor type, A	0.031
Clec4d	C-type lectin domain family 4, member d	0.031
Cd14	CD14 antigen	0.030
Slc15a3	solute carrier family 15, member 3	0.029
Ptpn18	protein tyrosine phosphatase, non-receptor type 18	0.028
Cd8b1	CD8 antigen, beta chain 1	0.028
Tmem106a	transmembrane protein 106A	0.028
Kit	kit oncogene	0.028
Sit1	suppression inducing transmembrane adaptor 1	0.028
Rgs14	regulator of G-protein signaling 14	0.028
Ifitm6	interferon induced transmembrane protein 6	0.027
Pdcd1	programmed cell death 1	0.027
Irg1	immunoresponsive gene 1	0.027
Slpi	secretory leukocyte peptidase inhibitor	0.027
Mmp8	matrix metallopeptidase 8	0.027
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.027
Cd7	CD7 antigen	0.026
Ptafr	platelet-activating factor receptor	0.026
Mpeg1	macrophage expressed gene 1	0.026
Marco	macrophage receptor with collagenous structure	0.025
Ncf1	neutrophil cytosolic factor 1	0.025
Aif1	allograft inflammatory factor 1	0.025
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.024
Mcoln2	mucolipin 2	0.024
Pilra	paired immunoglobin-like type 2 receptor alpha	0.024
Cxcl2	chemokine (C-X-C motif) ligand 2	0.024
P2ry13	purinergic receptor P2Y, G-protein coupled 13	0.024
Fcrla	Fc receptor-like A	0.024	Mouse
Ggt5	gamma-glutamyltransferase 5	0.024
Alox5ap	arachidonate 5-lipoxygenase activating protein	0.024
Adamdec1	ADAM-like, decysin 1	0.024
Folr2	folate receptor 2 (fetal)	0.024
Fosl2	fos-like antigen 2	0.024
Snx20	sorting nexin 20	0.023
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.023
Calcrl	calcitonin receptor-like	0.022
Lck	lymphocyte protein tyrosine kinase	0.022	Mouse
Tifa	TRAF-interacting protein with forkhead-associated domain	0.022
Tnfaip2	tumor necrosis factor, alpha-induced protein 2	0.021
Ccr7	chemokine (C-C motif) receptor 7	0.021
P2ry6	pyrimidinergic receptor P2Y, G-protein coupled, 6	0.021
Aldh3b1	aldehyde dehydrogenase 3 family, member B1	0.021
Cd19	CD19 antigen	0.021
Ccl9	chemokine (C-C motif) ligand 9	0.020
Cd300lb	CD300 antigen like family member B	0.020	Mouse
Cd5l	CD5 antigen-like	0.020
Fcgr1	Fc receptor, IgG, high affinity I	0.020	Mouse
Gpr182	G protein-coupled receptor 182	0.020
Shc3	src homology 2 domain-containing transforming protein C3	0.020
Laptm5	lysosomal-associated protein transmembrane 5	0.020
Fpr1	formyl peptide receptor 1	0.020
Trem1	triggering receptor expressed on myeloid cells 1	0.020
Cd33	CD33 antigen	0.020
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.020
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.019
Vav1	vav 1 oncogene	0.019
Cd2	CD2 antigen	0.019
Meis2	Meis homeobox 2	0.019
Batf	basic leucine zipper transcription factor, ATF-like	0.019
Vpreb3	pre-B lymphocyte gene 3	0.019
C130050O18Rik	RIKEN cDNA C130050O18 gene	0.018
Sirpa	signal-regulatory protein alpha	0.018
Crtam	cytotoxic and regulatory T cell molecule	0.018
Dnase1l3	deoxyribonuclease 1-like 3	0.017
Il11	interleukin 11	0.017
Rasgrf2	RAS protein-specific guanine nucleotide-releasing factor 2	0.017
Apobr	apolipoprotein B receptor	0.017
Ebi3	Epstein-Barr virus induced gene 3	0.017
Ccl17	chemokine (C-C motif) ligand 17	0.017
Hmox1	heme oxygenase (decycling) 1	0.017
Gpr132	G protein-coupled receptor 132	0.016
Siglece	sialic acid binding Ig-like lectin E	0.016
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.016
Cd28	CD28 antigen	0.016
Pstpip1	proline-serine-threonine phosphatase-interacting protein 1	0.016
Lilrb3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.016
Itgax	integrin alpha X	0.016
Clec1b	C-type lectin domain family 1, member b	0.016
Treml4	triggering receptor expressed on myeloid cells-like 4	0.016
Cd160	CD160 antigen	0.016
Cxcr2	chemokine (C-X-C motif) receptor 2	0.016
Apobec1	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	0.016
Clec4a2	C-type lectin domain family 4, member a2	0.016
Gpsm3	G-protein signalling modulator 3 (AGS3-like, C. elegans)	0.016
Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	0.015
Pla2g4f	phospholipase A2, group IVF	0.015
Treml1	triggering receptor expressed on myeloid cells-like 1	0.015
Col13a1	collagen, type XIII, alpha 1	0.015
Slamf1	signaling lymphocytic activation molecule family member 1	0.015
Cd300ld	CD300 molecule-like family member d	0.015	Mouse
Il3ra	interleukin 3 receptor, alpha chain	0.014	Mouse
Ceacam10	carcinoembryonic antigen-related cell adhesion molecule 10	0.014
Itgae	integrin alpha E, epithelial-associated	0.014
Sh3kbp1	SH3-domain kinase binding protein 1	0.014
Ptprj	protein tyrosine phosphatase, receptor type, J	0.014
Fgd3	FYVE, RhoGEF and PH domain containing 3	0.014
Il5ra	interleukin 5 receptor, alpha	0.014	Mouse
Sema6b	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B	0.014
Gab2	growth factor receptor bound protein 2-associated protein 2	0.014
Prl8a2	prolactin family 8, subfamily a, member 2	0.014
Sh3bp2	SH3-domain binding protein 2	0.014
Camp	cathelicidin antimicrobial peptide	0.014
Ncf4	neutrophil cytosolic factor 4	0.013
C1qb	complement component 1, q subcomponent, beta polypeptide	0.013
Bdnf	brain derived neurotrophic factor	0.013
Tlr6	toll-like receptor 6	0.013
Cd3e	CD3 antigen, epsilon polypeptide	0.013
Rag1	recombination activating gene 1	0.013
Siglecg	sialic acid binding Ig-like lectin G	0.013
Rinl	Ras and Rab interactor-like	0.013
U46068	cDNA sequence U46068	0.013
Cd8a	CD8 antigen, alpha chain	0.013
Fcer2a	Fc receptor, IgE, low affinity II, alpha polypeptide	0.013
Ms4a1	membrane-spanning 4-domains, subfamily A, member 1	0.013
Spsb2	splA/ryanodine receptor domain and SOCS box containing 2	0.012
Map1lc3b	microtubule-associated protein 1 light chain 3 beta	0.012
Crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.012
Pxn	paxillin	0.012
Ly9	lymphocyte antigen 9	0.012
Pdgfb	platelet derived growth factor, B polypeptide	0.012
1810033B17Rik	RIKEN cDNA 1810033B17 gene	0.012
Ms4a6d	membrane-spanning 4-domains, subfamily A, member 6D	0.012
Fpr2	formyl peptide receptor 2	0.012
Lgals2	lectin, galactose-binding, soluble 2	0.012
Clnk	cytokine-dependent hematopoietic cell linker	0.012
Flt1	FMS-like tyrosine kinase 1	0.012
Klrb1c	killer cell lectin-like receptor subfamily B member 1C	0.012
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.012
P2ry12	purinergic receptor P2Y, G-protein coupled 12	0.012
Il1rn	interleukin 1 receptor antagonist	0.012
Ms4a2	membrane-spanning 4-domains, subfamily A, member 2	0.012
Mmp19	matrix metallopeptidase 19	0.011
Unc93b1	unc-93 homolog B1 (C. elegans)	0.011
Il1b	interleukin 1 beta	0.011
Pik3r6	phosphoinositide-3-kinase, regulatory subunit 6	0.011
Skap2	src family associated phosphoprotein 2	0.011
Pla2g2d	phospholipase A2, group IID	0.011
Ccbp2	chemokine binding protein 2	0.011
6330512M04Rik	RIKEN cDNA 6330512M04 gene	0.011
Mxd1	MAX dimerization protein 1	0.011
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.011
Notch4	Notch gene homolog 4 (Drosophila)	0.011
Pik3ap1	phosphoinositide-3-kinase adaptor protein 1	0.011
Spn	sialophorin	0.011
Renbp	renin binding protein	0.011
Vim	vimentin	0.011
Mpl	myeloproliferative leukemia virus oncogene	0.011
Ctsw	cathepsin W	0.011
Epor	erythropoietin receptor	0.011
Sykb	spleen tyrosine kinase	0.011
C1qc	complement component 1, q subcomponent, C chain	0.011
Ltb	lymphotoxin B	0.010
Sdc3	syndecan 3	0.010
Ccl6	chemokine (C-C motif) ligand 6	0.010
Il12rb1	interleukin 12 receptor, beta 1	0.010
Cd177	CD177 antigen	0.010
Fas	Fas (TNF receptor superfamily member 6)	0.010
Tifab	TRAF-interacting protein with forkhead-associated domain, family member B	0.010
Slamf8	SLAM family member 8	0.010
Lst1	leukocyte specific transcript 1	0.010
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.010
Sh2b3	SH2B adaptor protein 3	0.010
B3gnt8	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8	0.010
Zg16	zymogen granule protein 16	0.010
B3gnt3	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3	0.010