|
|
regulation of fatty acid metabolic process
|
GO:0019217 |
28 |
1.000
|
|
|
|
acylglycerol metabolic process
|
GO:0006639 |
55 |
0.999
|
|
|
|
positive regulation of triglyceride metabolic process
|
GO:0090208 |
9 |
0.998
|
|
|
|
cholesterol storage
|
GO:0010878 |
4 |
0.997
|
|
|
|
glycerolipid catabolic process
|
GO:0046503 |
16 |
0.995
|
|
|
|
neutral lipid metabolic process
|
GO:0006638 |
57 |
0.995
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.995
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.994
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.993
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.990
|
Human |
|
|
mapk cascade
|
GO:0000165 |
281 |
0.989
|
|
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
77 |
0.987
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.987
|
|
|
|
acylglycerol catabolic process
|
GO:0046464 |
11 |
0.987
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
40 |
0.979
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.979
|
|
|
|
lipid homeostasis
|
GO:0055088 |
63 |
0.975
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.972
|
|
|
|
regulation of lipid catabolic process
|
GO:0050994 |
15 |
0.967
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.966
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.966
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.964
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.960
|
|
|
|
regulation of nitrogen cycle metabolic process
|
GO:1903314 |
1 |
0.958
|
|
|
|
response to low density lipoprotein particle
|
GO:0055098 |
2 |
0.958
|
|
|
|
cellular lipid catabolic process
|
GO:0044242 |
52 |
0.957
|
|
|
|
triglyceride metabolic process
|
GO:0006641 |
51 |
0.956
|
|
|
|
positive regulation of fatty acid oxidation
|
GO:0046321 |
4 |
0.956
|
|
|
|
triglyceride catabolic process
|
GO:0019433 |
9 |
0.951
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.948
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.942
|
|
|
|
sensory perception of umami taste
|
GO:0050917 |
4 |
0.942
|
|
|
|
regulation of fatty acid oxidation
|
GO:0046320 |
10 |
0.941
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.940
|
|
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.939
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.938
|
|
|
|
regulation of glutamine family amino acid metabolic process
|
GO:0000820 |
1 |
0.937
|
|
|
|
regulation of triglyceride metabolic process
|
GO:0090207 |
17 |
0.933
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.923
|
|
|
|
regulation of phosphatidylcholine catabolic process
|
GO:0010899 |
2 |
0.922
|
|
|
|
lactation
|
GO:0007595 |
25 |
0.920
|
|
|
|
regulation of phospholipid catabolic process
|
GO:0060696 |
2 |
0.918
|
|
|
|
fatty acid oxidation
|
GO:0019395 |
28 |
0.910
|
|
|
|
termination of rna polymerase i transcription
|
GO:0006363 |
2 |
0.908
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.899
|
|
|
|
response to testosterone
|
GO:0033574 |
3 |
0.893
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.890
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.880
|
Mouse |
|
|
wound healing
|
GO:0042060 |
157 |
0.878
|
Human Mouse |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.876
|
|
|
|
negative regulation of interferon gamma mediated signaling pathway
|
GO:0060336 |
1 |
0.874
|
|
|
|
cellular response to increased oxygen levels
|
GO:0036295 |
1 |
0.874
|
Human |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.871
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.871
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.866
|
|
|
|
drug catabolic process
|
GO:0042737 |
2 |
0.864
|
|
|
|
response to alkaloid
|
GO:0043279 |
34 |
0.862
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.861
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.858
|
|
|
|
small molecule catabolic process
|
GO:0044282 |
71 |
0.856
|
|
|
|
hair cycle
|
GO:0042633 |
90 |
0.854
|
|
|
|
sequestering of triglyceride
|
GO:0030730 |
6 |
0.851
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.844
|
Mouse |
|
|
ammonia assimilation cycle
|
GO:0019676 |
2 |
0.840
|
|
|
|
positive regulation of apoptotic process involved in mammary gland involution
|
GO:0060058 |
4 |
0.834
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.824
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.816
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.812
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.812
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.810
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.806
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.805
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
28 |
0.804
|
Human |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.803
|
|
|
|
positive regulation of insulin receptor signaling pathway
|
GO:0046628 |
4 |
0.800
|
|
|
|
dna templated transcription termination
|
GO:0006353 |
4 |
0.800
|
|
|
|
circadian regulation of gene expression
|
GO:0032922 |
48 |
0.794
|
|
|
|
positive regulation of triglyceride catabolic process
|
GO:0010898 |
3 |
0.794
|
|
|
|
response to hypoxia
|
GO:0001666 |
58 |
0.790
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.782
|
|
|
|
response to purine containing compound
|
GO:0014074 |
28 |
0.780
|
|
|
|
lipid catabolic process
|
GO:0016042 |
69 |
0.776
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.775
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.772
|
|
|
|
intestinal cholesterol absorption
|
GO:0030299 |
5 |
0.762
|
Zebrafish |
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.743
|
|
|
|
transcription initiation from rna polymerase i promoter
|
GO:0006361 |
4 |
0.742
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
49 |
0.741
|
|
|
|
hair follicle development
|
GO:0001942 |
85 |
0.738
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.735
|
|
|
|
neutral lipid catabolic process
|
GO:0046461 |
11 |
0.735
|
|
|
|
neutral lipid biosynthetic process
|
GO:0046460 |
18 |
0.730
|
|
|
|
regulation of vitamin d biosynthetic process
|
GO:0060556 |
1 |
0.727
|
|
|
|
regulation of urea metabolic process
|
GO:0034255 |
1 |
0.726
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.722
|
Mouse |
|
|
regulation of lipid storage
|
GO:0010883 |
20 |
0.720
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.719
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.713
|
|
|
|
response to increased oxygen levels
|
GO:0036296 |
2 |
0.712
|
Human |
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.711
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.703
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.695
|
Mouse |
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.691
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.691
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.687
|
|
|
|
regulation of vitamin metabolic process
|
GO:0030656 |
3 |
0.676
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.676
|
|
|
|
response to nitric oxide
|
GO:0071731 |
4 |
0.673
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.669
|
Worm |
|
|
keratinocyte migration
|
GO:0051546 |
3 |
0.667
|
|
|
|
membrane assembly
|
GO:0071709 |
12 |
0.662
|
|
|
|
cellular response to prostaglandin stimulus
|
GO:0071379 |
2 |
0.658
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.654
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
57 |
0.653
|
Mouse |
|
|
acylglycerol homeostasis
|
GO:0055090 |
16 |
0.651
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.646
|
|
|
|
membrane biogenesis
|
GO:0044091 |
12 |
0.646
|
|
|
|
gas homeostasis
|
GO:0033483 |
3 |
0.645
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.642
|
Worm |
|
|
regulation of the force of heart contraction
|
GO:0002026 |
17 |
0.640
|
|
|
|
monocarboxylic acid catabolic process
|
GO:0072329 |
27 |
0.638
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.637
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.634
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.634
|
|
|
|
regulation of response to food
|
GO:0032095 |
10 |
0.625
|
|
|
|
response to monosaccharide
|
GO:0034284 |
67 |
0.622
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
75 |
0.620
|
|
|
|
response to bile acid
|
GO:1903412 |
1 |
0.615
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
21 |
0.614
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.613
|
|
|
|
regulation of receptor activity
|
GO:0010469 |
41 |
0.613
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.611
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.610
|
|
|
|
lipid transport
|
GO:0006869 |
98 |
0.605
|
Zebrafish Worm |
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.603
|
|
|
|
trachea development
|
GO:0060438 |
18 |
0.602
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
56 |
0.597
|
Mouse |
|
|
membrane raft assembly
|
GO:0001765 |
3 |
0.596
|
|
|
|
regulation of the force of heart contraction by chemical signal
|
GO:0003057 |
5 |
0.592
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.584
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.584
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.582
|
|
|
|
activation of janus kinase activity
|
GO:0042976 |
2 |
0.580
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.578
|
|
|
|
interleukin 18 mediated signaling pathway
|
GO:0035655 |
2 |
0.572
|
|
|
|
alpha amino acid metabolic process
|
GO:1901605 |
59 |
0.565
|
|
|
|
response to lipoprotein particle
|
GO:0055094 |
5 |
0.563
|
|
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
24 |
0.562
|
|
|
|
phospholipid catabolic process
|
GO:0009395 |
5 |
0.562
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.558
|
Human |
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.547
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.546
|
Mouse |
|
|
protein nitrosylation
|
GO:0017014 |
4 |
0.546
|
|
|
|
sterol homeostasis
|
GO:0055092 |
45 |
0.543
|
|
|
|
triglyceride biosynthetic process
|
GO:0019432 |
17 |
0.543
|
|
|
|
triglyceride homeostasis
|
GO:0070328 |
15 |
0.541
|
|
|
|
response to vitamin a
|
GO:0033189 |
1 |
0.541
|
|
|
|
intestinal absorption
|
GO:0050892 |
13 |
0.537
|
Zebrafish |
|
|
negative regulation of release of cytochrome c from mitochondria
|
GO:0090201 |
6 |
0.536
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.530
|
|
|
|
regulation of ammonia assimilation cycle
|
GO:2001248 |
1 |
0.527
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.520
|
Mouse |
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.514
|
Human |
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.513
|
|
|
|
creatine metabolic process
|
GO:0006600 |
4 |
0.510
|
|
|
|
organic acid catabolic process
|
GO:0016054 |
51 |
0.508
|
|
|
|
nitric oxide metabolic process
|
GO:0046209 |
25 |
0.507
|
|
|
|
regulation of generation of precursor metabolites and energy
|
GO:0043467 |
38 |
0.506
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.502
|
|
|
|
body fluid secretion
|
GO:0007589 |
53 |
0.500
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.500
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.499
|
|
|
|
plasma lipoprotein particle clearance
|
GO:0034381 |
13 |
0.498
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.490
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.488
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.483
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.481
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
54 |
0.480
|
Mouse |
|
|
creatinine metabolic process
|
GO:0046449 |
3 |
0.479
|
|
|
|
cellular response to bile acid
|
GO:1903413 |
1 |
0.479
|
|
|
|
cholesterol transport
|
GO:0030301 |
38 |
0.478
|
Zebrafish |
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.475
|
|
|
|
adrenergic receptor signaling pathway
|
GO:0071875 |
13 |
0.474
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.474
|
|
|
|
glutamine family amino acid metabolic process
|
GO:0009064 |
15 |
0.470
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.468
|
Human |
|
|
insulin receptor signaling pathway
|
GO:0008286 |
49 |
0.467
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.467
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.465
|
Mouse |
|
|
response to amphetamine
|
GO:0001975 |
16 |
0.462
|
|
|
|
receptor biosynthetic process
|
GO:0032800 |
3 |
0.459
|
|
|
|
negative regulation of protein kinase b signaling
|
GO:0051898 |
18 |
0.458
|
|
|
|
positive regulation of glycogen metabolic process
|
GO:0070875 |
8 |
0.457
|
|
|
|
sterol transmembrane transport
|
GO:0035382 |
2 |
0.456
|
|
|
|
negative regulation of reactive oxygen species biosynthetic process
|
GO:1903427 |
0 |
0.456
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
4 |
0.455
|
|
|
|
positive regulation of phagocytosis engulfment
|
GO:0060100 |
3 |
0.453
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.452
|
|
|
|
eye photoreceptor cell development
|
GO:0042462 |
31 |
0.451
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
73 |
0.450
|
|
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
9 |
0.448
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.447
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.442
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.438
|
|
|
|
regulation of androgen receptor signaling pathway
|
GO:0060765 |
3 |
0.437
|
|
|
|
positive regulation of smooth muscle cell migration
|
GO:0014911 |
4 |
0.435
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.435
|
|
|
|
positive regulation of lipid storage
|
GO:0010884 |
10 |
0.434
|
|
|
|
phototransduction
|
GO:0007602 |
17 |
0.434
|
|
|
|
regulation of adrenergic receptor signaling pathway
|
GO:0071877 |
4 |
0.429
|
|
|
|
cholesterol homeostasis
|
GO:0042632 |
44 |
0.428
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.426
|
Human |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.426
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.426
|
|
|
|
response to estrogen
|
GO:0043627 |
24 |
0.422
|
|
|
|
cellular response to vitamin
|
GO:0071295 |
2 |
0.419
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.417
|
|
|
|
pyruvate metabolic process
|
GO:0006090 |
28 |
0.415
|
|
|
|
lipid modification
|
GO:0030258 |
65 |
0.414
|
|
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
26 |
0.413
|
|
|
|
triglyceride mobilization
|
GO:0006642 |
5 |
0.408
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.408
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.405
|
|
|
|
platelet activation
|
GO:0030168 |
40 |
0.405
|
|
|
|
muscle cell cellular homeostasis
|
GO:0046716 |
12 |
0.405
|
Mouse |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.399
|
|
|
|
regulation of receptor biosynthetic process
|
GO:0010869 |
2 |
0.397
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.397
|
Human |
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.397
|
|
|
|
cellular response to interleukin 18
|
GO:0071351 |
3 |
0.396
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.395
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.392
|
|
|
|
smooth muscle contraction
|
GO:0006939 |
44 |
0.391
|
|
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
50 |
0.390
|
|
|
|
regulation of glucose metabolic process
|
GO:0010906 |
60 |
0.385
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.381
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.380
|
|
|
|
negative regulation of lipid metabolic process
|
GO:0045833 |
30 |
0.379
|
|
|
|
inflammatory response to wounding
|
GO:0090594 |
4 |
0.376
|
|
|
|
rhodopsin mediated signaling pathway
|
GO:0016056 |
4 |
0.376
|
|
|
|
regulation of intestinal cholesterol absorption
|
GO:0030300 |
4 |
0.375
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.373
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.371
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
26 |
0.371
|
|
|
|
nitric oxide mediated signal transduction
|
GO:0007263 |
4 |
0.367
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.366
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.363
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.361
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.361
|
Mouse |
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.360
|
|
|
|
macrophage derived foam cell differentiation
|
GO:0010742 |
6 |
0.360
|
|
|
|
adenylate cyclase activating dopamine receptor signaling pathway
|
GO:0007191 |
7 |
0.359
|
|
|
|
positive regulation of chromatin modification
|
GO:1903310 |
28 |
0.358
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.358
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.356
|
|
|
|
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway
|
GO:1902176 |
4 |
0.354
|
|
|
|
regulation of steroid biosynthetic process
|
GO:0050810 |
26 |
0.353
|
|
|
|
negative regulation of sequestering of triglyceride
|
GO:0010891 |
2 |
0.352
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.349
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.348
|
|
|
|
negative regulation of systemic arterial blood pressure
|
GO:0003085 |
15 |
0.346
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.344
|
|
|
|
p38mapk cascade
|
GO:0038066 |
4 |
0.343
|
Mouse |
|
|
cellular response to bacterial lipoprotein
|
GO:0071220 |
3 |
0.342
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.342
|
Human Mouse |
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.340
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.339
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
23 |
0.336
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.335
|
|
|
|
positive regulation of adrenergic receptor signaling pathway
|
GO:0071879 |
3 |
0.334
|
|
|
|
mammary gland lobule development
|
GO:0061377 |
22 |
0.334
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.331
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.329
|
|
|
|
response to caffeine
|
GO:0031000 |
6 |
0.328
|
|
|
|
lipoprotein transport
|
GO:0042953 |
7 |
0.328
|
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.327
|
Human |
|
|
glucose import
|
GO:0046323 |
32 |
0.326
|
|
|
|
brown fat cell differentiation
|
GO:0050873 |
36 |
0.326
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.323
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.320
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
43 |
0.318
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.316
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.316
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.314
|
|
|
|
fatty acid catabolic process
|
GO:0009062 |
25 |
0.312
|
|
|
|
regulation of response to oxidative stress
|
GO:1902882 |
19 |
0.312
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.311
|
|
|
|
positive regulation of creb transcription factor activity
|
GO:0032793 |
4 |
0.310
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.310
|
|
|
|
transcription from rna polymerase i promoter
|
GO:0006360 |
13 |
0.308
|
|
|
|
negative regulation of androgen receptor signaling pathway
|
GO:0060766 |
3 |
0.306
|
|
|
|
regulation of carbohydrate biosynthetic process
|
GO:0043255 |
40 |
0.303
|
|
|
|
positive regulation of fatty acid metabolic process
|
GO:0045923 |
8 |
0.302
|
|
|
|
positive regulation of bone remodeling
|
GO:0046852 |
13 |
0.302
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.301
|
|
|
|
regulation of serotonin uptake
|
GO:0051611 |
2 |
0.297
|
|
|
|
regulation of calcidiol 1 monooxygenase activity
|
GO:0060558 |
1 |
0.297
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.296
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
56 |
0.295
|
|
|
|
regulation of removal of superoxide radicals
|
GO:2000121 |
4 |
0.294
|
|
|
|
regulation of monooxygenase activity
|
GO:0032768 |
7 |
0.294
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.294
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.294
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.294
|
|
|
|
lipid oxidation
|
GO:0034440 |
29 |
0.289
|
|
|
|
g protein coupled acetylcholine receptor signaling pathway
|
GO:0007213 |
4 |
0.289
|
|
|
|
cholesterol metabolic process
|
GO:0008203 |
56 |
0.289
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.287
|
|
|
|
negative regulation of endothelial cell proliferation
|
GO:0001937 |
8 |
0.287
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.281
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.281
|
Human |
|
|
g protein coupled receptor signaling pathway involved in heart process
|
GO:0086103 |
4 |
0.279
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.279
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.279
|
Human |
|
|
positive regulation of osteoclast differentiation
|
GO:0045672 |
15 |
0.279
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.279
|
|
|
|
serotonin receptor signaling pathway
|
GO:0007210 |
8 |
0.278
|
|
|
|
acylglycerol biosynthetic process
|
GO:0046463 |
18 |
0.278
|
|
|
|
negative regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042524 |
2 |
0.275
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
23 |
0.270
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.269
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.269
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.267
|
|
|
|
urea metabolic process
|
GO:0019627 |
3 |
0.266
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.265
|
Human |
|
|
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902043 |
13 |
0.264
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.264
|
|
|
|
regulation of peptide secretion
|
GO:0002791 |
77 |
0.263
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.261
|
|
|
|
regulation of triglyceride biosynthetic process
|
GO:0010866 |
10 |
0.260
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.260
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.259
|
Human |
|
|
regulation of triglyceride catabolic process
|
GO:0010896 |
5 |
0.259
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
37 |
0.259
|
|
|
|
positive regulation of coagulation
|
GO:0050820 |
13 |
0.258
|
|
|
|
retinal cone cell development
|
GO:0046549 |
8 |
0.257
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.257
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.254
|
|
|
|
cyclic nucleotide mediated signaling
|
GO:0019935 |
18 |
0.251
|
|
|
|
labyrinthine layer development
|
GO:0060711 |
49 |
0.250
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.249
|
|
|
|
positive regulation of lipid catabolic process
|
GO:0050996 |
6 |
0.249
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
77 |
0.249
|
|
|
|
regulation of cholesterol storage
|
GO:0010885 |
4 |
0.248
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.247
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.244
|
|
|
|
regulation of wound healing
|
GO:0061041 |
40 |
0.243
|
Human |
|
|
platelet derived growth factor receptor signaling pathway
|
GO:0048008 |
32 |
0.241
|
|
|
|
glutamine metabolic process
|
GO:0006541 |
8 |
0.239
|
|
|
|
response to corticosteroid
|
GO:0031960 |
20 |
0.239
|
|
|
|
superoxide metabolic process
|
GO:0006801 |
27 |
0.237
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
59 |
0.236
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.236
|
|
|
|
positive regulation by symbiont of defense related host nitric oxide production
|
GO:0052347 |
1 |
0.236
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.235
|
Human |
|
|
apoptotic process involved in mammary gland involution
|
GO:0060057 |
4 |
0.233
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.230
|
|
|
|
glycolytic process
|
GO:0006096 |
20 |
0.230
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
93 |
0.229
|
|
|
|
regulation of carbohydrate catabolic process
|
GO:0043470 |
12 |
0.228
|
|
|
|
positive regulation of histone modification
|
GO:0031058 |
28 |
0.226
|
|
|
|
response to fatty acid
|
GO:0070542 |
8 |
0.225
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.223
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.223
|
|
|
|
taurine metabolic process
|
GO:0019530 |
4 |
0.223
|
|
|
|
response to hyperoxia
|
GO:0055093 |
2 |
0.223
|
Human |
|
|
metanephric nephron development
|
GO:0072210 |
34 |
0.222
|
|
|
|
positive regulation of lipid biosynthetic process
|
GO:0046889 |
18 |
0.222
|
|
|
|
negative regulation of peptide hormone secretion
|
GO:0090278 |
16 |
0.221
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.221
|
|
|
|
regulation of gluconeogenesis
|
GO:0006111 |
30 |
0.220
|
|
|
|
response to glucocorticoid
|
GO:0051384 |
20 |
0.220
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.219
|
|
|
|
regulation of immune complex clearance by monocytes and macrophages
|
GO:0090264 |
2 |
0.218
|
|
|
|
positive regulation of apoptotic process involved in morphogenesis
|
GO:1902339 |
4 |
0.217
|
|
|
|
isoleucine metabolic process
|
GO:0006549 |
4 |
0.217
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.217
|
|
|
|
regulation of blood vessel size
|
GO:0050880 |
56 |
0.216
|
|
|
|
negative regulation of blood pressure
|
GO:0045776 |
22 |
0.215
|
|
|
|
energy reserve metabolic process
|
GO:0006112 |
39 |
0.215
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.214
|
Mouse |
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.214
|
|
|
|
response to lithium ion
|
GO:0010226 |
10 |
0.214
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
52 |
0.214
|
|
|
|
cellular carbohydrate catabolic process
|
GO:0044275 |
15 |
0.213
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.210
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.208
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.207
|
|
|
|
regulation of response to reactive oxygen species
|
GO:1901031 |
9 |
0.205
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.204
|
|
|
|
response to vitamin
|
GO:0033273 |
6 |
0.202
|
|
|
|
positive regulation of vasoconstriction
|
GO:0045907 |
4 |
0.202
|
|
|
|
genetic imprinting
|
GO:0071514 |
27 |
0.202
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.202
|
|
|
|
response to drug
|
GO:0042493 |
75 |
0.201
|
|
|
|
negative regulation of cellular response to insulin stimulus
|
GO:1900077 |
16 |
0.201
|
|
|
|
regulation of coagulation
|
GO:0050818 |
31 |
0.200
|
Human |
|
|
telencephalon development
|
GO:0021537 |
186 |
0.200
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
56 |
0.199
|
|
|
|
positive regulation of macrophage derived foam cell differentiation
|
GO:0010744 |
4 |
0.199
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.198
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.198
|
|
|
|
positive regulation of fat cell differentiation
|
GO:0045600 |
32 |
0.197
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.196
|
|
|
|
regulation of pigment cell differentiation
|
GO:0050932 |
7 |
0.196
|
|
|
|
positive regulation of cholesterol transport
|
GO:0032376 |
9 |
0.195
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.194
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.194
|
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
54 |
0.192
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.191
|
|
|
|
plasma membrane long chain fatty acid transport
|
GO:0015911 |
1 |
0.191
|
|
|
|
response to ph
|
GO:0009268 |
14 |
0.190
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.190
|
|
|
|
tyrosine phosphorylation of stat1 protein
|
GO:0042508 |
3 |
0.190
|
|
|
|
regulation of appetite
|
GO:0032098 |
12 |
0.188
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.188
|
|
|
|
metanephric glomerular mesangial cell proliferation involved in metanephros development
|
GO:0072262 |
3 |
0.188
|
|
|
|
cholesterol import
|
GO:0070508 |
2 |
0.187
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.186
|
|
|
|
response to defense related nitric oxide production by other organism involved in symbiotic interaction
|
GO:0052551 |
2 |
0.184
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.183
|
Human |
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.183
|
Human |
|
|
response to estradiol
|
GO:0032355 |
12 |
0.182
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.180
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.180
|
|
|
|
sterol metabolic process
|
GO:0016125 |
58 |
0.179
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.177
|
|
|
|
fatty acid transmembrane transport
|
GO:1902001 |
1 |
0.177
|
|
|
|
vitamin d biosynthetic process
|
GO:0042368 |
3 |
0.177
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.176
|
|
|
|
negative regulation of peptide secretion
|
GO:0002792 |
16 |
0.175
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.174
|
|
|
|
camp metabolic process
|
GO:0046058 |
40 |
0.172
|
|
|
|
regulation of melanocyte differentiation
|
GO:0045634 |
7 |
0.172
|
|
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
93 |
0.170
|
Mouse |
|
|
fatty acid beta oxidation
|
GO:0006635 |
16 |
0.170
|
|
|
|
dna methylation
|
GO:0006306 |
43 |
0.169
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.169
|
|
|
|
nuclear envelope organization
|
GO:0006998 |
11 |
0.168
|
|
|
|
glutamate receptor signaling pathway
|
GO:0007215 |
35 |
0.168
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.167
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
62 |
0.167
|
|
|
|
lipid storage
|
GO:0019915 |
36 |
0.167
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.167
|
Mouse |
|
|
anatomical structure maturation
|
GO:0071695 |
49 |
0.166
|
|
|
|
peptidyl cysteine modification
|
GO:0018198 |
8 |
0.165
|
|
|
|
tissue migration
|
GO:0090130 |
68 |
0.165
|
|
|
|
response to fructose
|
GO:0009750 |
2 |
0.164
|
|
|
|
metanephric glomerular mesangium development
|
GO:0072223 |
3 |
0.163
|
|
|
|
regulation of histone acetylation
|
GO:0035065 |
19 |
0.163
|
|
|
|
regulation of sequestering of triglyceride
|
GO:0010889 |
6 |
0.163
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
39 |
0.161
|
Human |
|
|
regulation of histone deacetylation
|
GO:0031063 |
12 |
0.161
|
|
|
|
cardiac chamber development
|
GO:0003205 |
108 |
0.161
|
Mouse |
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
41 |
0.160
|
|
|
|
sterol transport
|
GO:0015918 |
38 |
0.160
|
Zebrafish |
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.160
|
|
|
|
glycogen biosynthetic process
|
GO:0005978 |
14 |
0.159
|
|
|
|
regulation of protein import into nucleus translocation
|
GO:0033158 |
2 |
0.159
|
|
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
37 |
0.158
|
|
|
|
carboxylic acid catabolic process
|
GO:0046395 |
51 |
0.158
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.158
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.157
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.156
|
|
|
|
negative regulation of neurotransmitter uptake
|
GO:0051581 |
2 |
0.156
|
|
|
|
response to food
|
GO:0032094 |
17 |
0.155
|
|
|
|
prolactin signaling pathway
|
GO:0038161 |
5 |
0.155
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.154
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.154
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
59 |
0.153
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.153
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.152
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.151
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.151
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.150
|
|
|
|
dna templated transcription initiation
|
GO:0006352 |
13 |
0.150
|
|
|
|
regulation of osteoclast differentiation
|
GO:0045670 |
36 |
0.149
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.148
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.148
|
|
|
|
response to epidermal growth factor
|
GO:0070849 |
4 |
0.147
|
|