IMP

Process View

Mus musculus

1 genes annotated in mouse

regulation of vitamin d biosynthetic process

Any process that modulates the rate frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of vitamin d biosynthetic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of vitamin d biosynthetic process" (in gray)

Name	Description	Probability	Func Analog Organism
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.993
Lepr	leptin receptor	0.979
Tgfb1	transforming growth factor, beta 1	0.936
Csf1	colony stimulating factor 1 (macrophage)	0.934
Lep	leptin	0.908
Col1a1	collagen, type I, alpha 1	0.898
Esr1	estrogen receptor 1 (alpha)	0.811
Tnf	tumor necrosis factor	0.810
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.793
Cav1	caveolin 1, caveolae protein	0.727
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.693
Nos3	nitric oxide synthase 3, endothelial cell	0.604
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.556
Insr	insulin receptor	0.370
Nos2	nitric oxide synthase 2, inducible	0.356
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.325
Tlr2	toll-like receptor 2	0.265
Apoe	apolipoprotein E	0.226
Rxra	retinoid X receptor alpha	0.223
Lyz2	lysozyme 2	0.221
Trp53	transformation related protein 53	0.196
Foxn1	forkhead box N1	0.189
Stat3	signal transducer and activator of transcription 3	0.188
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.173
Il10	interleukin 10	0.166
Tlr4	toll-like receptor 4	0.162
Ptgs2	prostaglandin-endoperoxide synthase 2	0.148
Esr2	estrogen receptor 2 (beta)	0.142
Tead3	TEA domain family member 3	0.137
Smad3	MAD homolog 3 (Drosophila)	0.136
Bcl3	B-cell leukemia/lymphoma 3	0.129
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.125
Slc26a1	solute carrier family 26 (sulfate transporter), member 1	0.100
Mmp9	matrix metallopeptidase 9	0.100
Gata6	GATA binding protein 6	0.097
Pparg	peroxisome proliferator activated receptor gamma	0.094	Mouse
Vav2	vav 2 oncogene	0.091
Socs1	suppressor of cytokine signaling 1	0.090
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.085
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.085
Pck1	phosphoenolpyruvate carboxykinase 1, cytosolic	0.079
Fas	Fas (TNF receptor superfamily member 6)	0.077
Agpat2	1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)	0.073
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.069
Col5a1	collagen, type V, alpha 1	0.067
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.067
Pnpla2	patatin-like phospholipase domain containing 2	0.066
Il6st	interleukin 6 signal transducer	0.064
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.060
Gata4	GATA binding protein 4	0.057
Spp1	secreted phosphoprotein 1	0.054
Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.053
Hpd	4-hydroxyphenylpyruvic acid dioxygenase	0.050
Dmgdh	dimethylglycine dehydrogenase precursor	0.050
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.050
Npr1	natriuretic peptide receptor 1	0.048
Nr1h4	nuclear receptor subfamily 1, group H, member 4	0.048	Mouse
Egfr	epidermal growth factor receptor	0.046
Apoa1	apolipoprotein A-I	0.044
Ar	androgen receptor	0.043
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.043
Ahsg	alpha-2-HS-glycoprotein	0.042
Il1a	interleukin 1 alpha	0.039
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.038
Ccl2	chemokine (C-C motif) ligand 2	0.038
Igf1	insulin-like growth factor 1	0.038
Nr1i2	nuclear receptor subfamily 1, group I, member 2	0.037	Mouse
Azgp1	alpha-2-glycoprotein 1, zinc	0.037
Fam20c	family with sequence similarity 20, member C	0.037
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.036
Ncoa3	nuclear receptor coactivator 3	0.036
Agtr1a	angiotensin II receptor, type 1a	0.036
Cyp2d26	cytochrome P450, family 2, subfamily d, polypeptide 26	0.036
Mocs1	molybdenum cofactor synthesis 1	0.035
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.035
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.033
Fabp1	fatty acid binding protein 1, liver	0.032
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.032
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.031	Human
Sult1b1	sulfotransferase family 1B, member 1	0.031
F12	coagulation factor XII (Hageman factor)	0.031
Clec4e	C-type lectin domain family 4, member e	0.030
Lipe	lipase, hormone sensitive	0.030
Adipoq	adiponectin, C1Q and collagen domain containing	0.030
Vhl	von Hippel-Lindau tumor suppressor	0.030
Cidec	cell death-inducing DFFA-like effector c	0.029
Kitl	kit ligand	0.029
Lrp5	low density lipoprotein receptor-related protein 5	0.028
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.028
Slc12a1	solute carrier family 12, member 1	0.027
Rdh16	retinol dehydrogenase 16	0.027
Il1r1	interleukin 1 receptor, type I	0.026
Sardh	sarcosine dehydrogenase	0.025
Gcgr	glucagon receptor	0.025
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.025
Plcg1	phospholipase C, gamma 1	0.025
Slpi	secretory leukocyte peptidase inhibitor	0.024
Il2rg	interleukin 2 receptor, gamma chain	0.024
Gdf15	growth differentiation factor 15	0.024
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.023
Lgals2	lectin, galactose-binding, soluble 2	0.023
Nos1	nitric oxide synthase 1, neuronal	0.023
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.023
Aqp7	aquaporin 7	0.022
Vegfa	vascular endothelial growth factor A	0.022
Ltbr	lymphotoxin B receptor	0.022
Gc	group specific component	0.022
Thra	thyroid hormone receptor alpha	0.022
Aldob	aldolase B, fructose-bisphosphate	0.022
Slc34a1	solute carrier family 34 (sodium phosphate), member 1	0.022
Apob	apolipoprotein B	0.021
Apoa4	apolipoprotein A-IV	0.021
Hnf4a	hepatic nuclear factor 4, alpha	0.021
Phlda2	pleckstrin homology-like domain, family A, member 2	0.021
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.021
Agrp	agouti related protein	0.021
Scd1	stearoyl-Coenzyme A desaturase 1	0.021
Spry4	sprouty homolog 4 (Drosophila)	0.020
Ccr2	chemokine (C-C motif) receptor 2	0.020
Il4ra	interleukin 4 receptor, alpha	0.019
Lrp1	low density lipoprotein receptor-related protein 1	0.019
Irs2	insulin receptor substrate 2	0.019
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.018
Apoh	apolipoprotein H	0.018
Abcc2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	0.018
Bscl2	Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)	0.017
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.017
Fam83f	family with sequence similarity 83, member F	0.017
C3	complement component 3	0.017
Lpin1	lipin 1	0.017
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.017
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.017
Ano6	anoctamin 6	0.017
P2ry2	purinergic receptor P2Y, G-protein coupled 2	0.017
Myd88	myeloid differentiation primary response gene 88	0.017
Foxa2	forkhead box A2	0.016
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.016
Itga5	integrin alpha 5 (fibronectin receptor alpha)	0.016
Pten	phosphatase and tensin homolog	0.016
Hoxa2	homeobox A2	0.016
Notch2	Notch gene homolog 2 (Drosophila)	0.016
Rab17	RAB17, member RAS oncogene family	0.016
Mgmt	O-6-methylguanine-DNA methyltransferase	0.015
Cyp3a13	cytochrome P450, family 3, subfamily a, polypeptide 13	0.015
Cyp27b1	cytochrome P450, family 27, subfamily b, polypeptide 1	0.015
Pcdh12	protocadherin 12	0.015
Soat2	sterol O-acyltransferase 2	0.015
C5ar1	complement component 5a receptor 1	0.015
Elk4	ELK4, member of ETS oncogene family	0.015
Lipa	lysosomal acid lipase A	0.015
Npc1	Niemann Pick type C1	0.015
Cyp2b10	cytochrome P450, family 2, subfamily b, polypeptide 10	0.015
Acsm3	acyl-CoA synthetase medium-chain family member 3	0.014
Twist1	twist homolog 1 (Drosophila)	0.014
She	src homology 2 domain-containing transforming protein E	0.014
Icam1	intercellular adhesion molecule 1	0.014
Cyp4b1	cytochrome P450, family 4, subfamily b, polypeptide 1	0.014
Pax8	paired box gene 8	0.014
Runx1	runt related transcription factor 1	0.014
Ldlr	low density lipoprotein receptor	0.014
Hgd	homogentisate 1, 2-dioxygenase	0.014
C1qtnf1	C1q and tumor necrosis factor related protein 1	0.014
Il6	interleukin 6	0.014
Plin1	perilipin 1	0.014
Tmprss2	transmembrane protease, serine 2	0.014
Ddr2	discoidin domain receptor family, member 2	0.013
Klk1b4	kallikrein 1-related pepidase b4	0.013
Thbs1	thrombospondin 1	0.013
Bche	butyrylcholinesterase	0.013
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.013
G6pc	glucose-6-phosphatase, catalytic	0.013
Stk4	serine/threonine kinase 4	0.013
Tead4	TEA domain family member 4	0.013
Khk	ketohexokinase	0.013
Maff	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)	0.013
Vnn1	vanin 1	0.013
Vav3	vav 3 oncogene	0.013
Efna5	ephrin A5	0.013
Crygs	crystallin, gamma S	0.013
Fam83g	family with sequence similarity 83, member G	0.012
Ggnbp1	gametogenetin binding protein 1	0.012
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.012
Nr1i3	nuclear receptor subfamily 1, group I, member 3	0.012	Mouse
Plau	plasminogen activator, urokinase	0.012
Sirt1	sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)	0.012
Mat1a	methionine adenosyltransferase I, alpha	0.012
Plaur	plasminogen activator, urokinase receptor	0.012
Slc34a2	solute carrier family 34 (sodium phosphate), member 2	0.012
Iyd	iodotyrosine deiodinase	0.012
Gpd2	glycerol phosphate dehydrogenase 2, mitochondrial	0.012
Rag2	recombination activating gene 2	0.012
Stk40	serine/threonine kinase 40	0.012
Slc22a18	solute carrier family 22 (organic cation transporter), member 18	0.012
Epha2	Eph receptor A2	0.011
Prrx2	paired related homeobox 2	0.011
Lect2	leukocyte cell-derived chemotaxin 2	0.011
Adrb3	adrenergic receptor, beta 3	0.011
Asgr2	asialoglycoprotein receptor 2	0.011
Abcc6	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	0.011
Irf1	interferon regulatory factor 1	0.011
Hamp	hepcidin antimicrobial peptide	0.011
Map3k6	mitogen-activated protein kinase kinase kinase 6	0.011
Cxcl12	chemokine (C-X-C motif) ligand 12	0.011
Tnfaip2	tumor necrosis factor, alpha-induced protein 2	0.011
Cxcl2	chemokine (C-X-C motif) ligand 2	0.011
Klk1b5	kallikrein 1-related peptidase b5	0.011
Kl	klotho	0.011
Gjb5	gap junction protein, beta 5	0.011
Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	0.011
Fam83h	family with sequence similarity 83, member H	0.011
Slc2a2	solute carrier family 2 (facilitated glucose transporter), member 2	0.011
Junb	Jun-B oncogene	0.011
F2rl2	coagulation factor II (thrombin) receptor-like 2	0.011
Gna11	guanine nucleotide binding protein, alpha 11	0.011
Ggt1	gamma-glutamyltransferase 1	0.011
Cdhr5	cadherin-related family member 5	0.011
Cxcr2	chemokine (C-X-C motif) receptor 2	0.010
Casp1	caspase 1	0.010
Rara	retinoic acid receptor, alpha	0.010
Myl7	myosin, light polypeptide 7, regulatory	0.010
Habp2	hyaluronic acid binding protein 2	0.010
Car5a	carbonic anhydrase 5a, mitochondrial	0.010
Bik	BCL2-interacting killer	0.010
Sult1d1	sulfotransferase family 1D, member 1	0.010
Fbp2	fructose bisphosphatase 2	0.010
Fosl2	fos-like antigen 2	0.010
Orm2	orosomucoid 2	0.010