Mus musculus

64 known processes

Cbx3

chromobox homolog 3 (Drosophila HP1 gamma)

(Aliases: HP1g,MGC118084,M32)

Cbx3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromatin modification GO:0016568 187 0.621
Fly
chromatin organization GO:0006325 206 0.526
Fly
spermatogenesis GO:0007283 284 0.456
male gamete generation GO:0048232 285 0.310
protein methylation GO:0006479 81 0.283
Fly
fourth ventricle development GO:0021592 2 0.241
dna metabolic process GO:0006259 303 0.220
Fly
histone h2a monoubiquitination GO:0035518 1 0.220
histone h3 k36 demethylation GO:0070544 2 0.216
histone h2a ubiquitination GO:0033522 3 0.215
protein modification by small protein conjugation or removal GO:0070647 207 0.194
cellular polysaccharide catabolic process GO:0044247 5 0.186
dna methylation GO:0006306 43 0.173
Fly
regulation of histone methylation GO:0031060 30 0.165
Fly
histone monoubiquitination GO:0010390 3 0.160
dna hypermethylation GO:0044026 3 0.156
Fly
rna interference GO:0016246 2 0.118
histone methylation GO:0016571 71 0.106
Fly
cellular response to lipid GO:0071396 145 0.100
embryonic organ morphogenesis GO:0048562 276 0.098
oxidation reduction process GO:0055114 342 0.093
apoptotic signaling pathway GO:0097190 306 0.090
cellular amino acid metabolic process GO:0006520 103 0.089
signal transduction by p53 class mediator GO:0072331 51 0.087
intracellular receptor signaling pathway GO:0030522 74 0.086
protein ubiquitination GO:0016567 171 0.086
leukocyte differentiation GO:0002521 342 0.084
ventricular system development GO:0021591 27 0.083
spermatid development GO:0007286 108 0.079
demethylation GO:0070988 23 0.078
membrane organization GO:0061024 245 0.075
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.073
regulation of neural precursor cell proliferation GO:2000177 70 0.072
regulation of dna methylation GO:0044030 12 0.071
Fly
regionalization GO:0003002 337 0.071
protein catabolic process GO:0030163 221 0.070
3 utr mediated mrna stabilization GO:0070935 2 0.069
intrinsic apoptotic signaling pathway GO:0097193 132 0.068
dna alkylation GO:0006305 43 0.067
Fly
cellular response to dna damage stimulus GO:0006974 207 0.066
negative regulation of cellular component organization GO:0051129 194 0.065
development of primary sexual characteristics GO:0045137 143 0.065
Worm
protein localization to chromatin GO:0071168 3 0.063
covalent chromatin modification GO:0016569 163 0.063
Fly
formation of organ boundary GO:0010160 1 0.062
protein modification by small protein conjugation GO:0032446 187 0.061
translation GO:0006412 93 0.061
chromosome segregation GO:0007059 48 0.060
third ventricle development GO:0021678 3 0.060
circadian rhythm GO:0007623 114 0.060
histone lysine demethylation GO:0070076 13 0.060
peptidyl lysine modification GO:0018205 77 0.059
Fly
amine metabolic process GO:0009308 45 0.057
chromatin assembly or disassembly GO:0006333 16 0.056
Fly
histone h3 k27 demethylation GO:0071557 4 0.056
camera type eye development GO:0043010 266 0.055
cellular glucan metabolic process GO:0006073 32 0.053
regulation of glycogen catabolic process GO:0005981 2 0.053
oocyte axis specification GO:0007309 2 0.052
regulation of protein stability GO:0031647 52 0.052
dna conformation change GO:0071103 37 0.051
Fly
mesenchyme development GO:0060485 152 0.051
polysaccharide metabolic process GO:0005976 39 0.051
multi multicellular organism process GO:0044706 109 0.050
midbrain hindbrain boundary morphogenesis GO:0021555 4 0.050
histone modification GO:0016570 159 0.049
Fly
germ cell development GO:0007281 185 0.048
Worm
regulation of mitotic cell cycle GO:0007346 126 0.048
dna modification GO:0006304 50 0.048
Fly
ras protein signal transduction GO:0007265 77 0.048
Worm
regulation of chromatin modification GO:1903308 57 0.048
Fly
negative regulation of rna splicing GO:0033119 12 0.048
lymphocyte differentiation GO:0030098 242 0.047
regulation of organelle organization GO:0033043 289 0.047
Fly
regulation of apoptotic signaling pathway GO:2001233 197 0.047
lung development GO:0030324 164 0.046
dna repair GO:0006281 107 0.046
regulation of peptidase activity GO:0052547 96 0.045
regulation of transcription by chromatin organization GO:0034401 0 0.045
negative regulation of apoptotic signaling pathway GO:2001234 104 0.045
protein dealkylation GO:0008214 13 0.044
response to steroid hormone GO:0048545 56 0.044
forebrain development GO:0030900 302 0.044
positive regulation of protein modification process GO:0031401 299 0.044
Fly
regulation of cellular response to stress GO:0080135 159 0.043
macromolecule catabolic process GO:0009057 281 0.043
protein demethylation GO:0006482 13 0.043
mitotic cell cycle GO:0000278 195 0.042
axonogenesis GO:0007409 274 0.041
negative regulation of molecular function GO:0044092 258 0.041
histone h3 k9 dimethylation GO:0036123 4 0.041
Fly
intracellular mrna localization GO:0008298 4 0.041
epithelial tube morphogenesis GO:0060562 303 0.041
regulation of cell activation GO:0050865 289 0.041
positive regulation of growth GO:0045927 104 0.040
Worm
regulation of circadian rhythm GO:0042752 58 0.039
regulation of transferase activity GO:0051338 263 0.039
nucleosome positioning GO:0016584 4 0.039
stem cell development GO:0048864 219 0.038
b cell activation GO:0042113 161 0.038
cell type specific apoptotic process GO:0097285 268 0.038
macromolecule methylation GO:0043414 120 0.037
Fly
negative regulation of cell proliferation GO:0008285 296 0.037
response to organic cyclic compound GO:0014070 198 0.036
regulation of binding GO:0051098 111 0.036
negative regulation of organelle organization GO:0010639 90 0.036
regulation of b cell activation GO:0050864 81 0.035
sensory organ morphogenesis GO:0090596 242 0.035
response to lipopolysaccharide GO:0032496 128 0.035
engulfment of apoptotic cell GO:0043652 3 0.034
respiratory tube development GO:0030323 167 0.034
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.034
regulation of cellular component biogenesis GO:0044087 181 0.034
Fly
chromatin assembly GO:0031497 13 0.034
Fly
axon guidance GO:0007411 141 0.033
compound eye development GO:0048749 1 0.032
nucleocytoplasmic transport GO:0006913 139 0.032
organelle fission GO:0048285 170 0.032
response to molecule of bacterial origin GO:0002237 143 0.032
negative regulation of phagocytosis GO:0050765 4 0.031
midbrain hindbrain boundary development GO:0030917 9 0.031
endocytosis GO:0006897 168 0.030
female gamete generation GO:0007292 74 0.030
Worm
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.030
glucan metabolic process GO:0044042 32 0.029
posttranscriptional regulation of gene expression GO:0010608 155 0.029
cellular macromolecule catabolic process GO:0044265 206 0.029
regulation of cellular amine metabolic process GO:0033238 20 0.028
regulation of intrinsic apoptotic signaling pathway by p53 class mediator GO:1902253 13 0.028
positive regulation of apoptotic process GO:0043065 217 0.028
palate development GO:0060021 76 0.027
regulation of cell cycle GO:0051726 281 0.027
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.027
regulation of lymphocyte activation GO:0051249 240 0.027
protein alkylation GO:0008213 81 0.027
Fly
rna splicing via transesterification reactions GO:0000375 43 0.026
regulation of wnt signaling pathway GO:0030111 123 0.026
lateral inhibition GO:0046331 1 0.026
stem cell differentiation GO:0048863 268 0.026
myeloid cell differentiation GO:0030099 233 0.026
rhythmic process GO:0048511 174 0.026
cellular carbohydrate metabolic process GO:0044262 119 0.025
respiratory system development GO:0060541 190 0.024
chronological cell aging GO:0001300 1 0.024
negative regulation of apoptotic cell clearance GO:2000426 1 0.024
cellular amine metabolic process GO:0044106 44 0.023
response to heat GO:0009408 27 0.023
regulation of mrna splicing via spliceosome GO:0048024 32 0.023
segment specification GO:0007379 15 0.023
segmentation GO:0035282 93 0.023
mrna processing GO:0006397 63 0.023
regulation of hormone levels GO:0010817 211 0.022
negative regulation of protein modification process GO:0031400 163 0.022
extrinsic apoptotic signaling pathway GO:0097191 126 0.022
neuron apoptotic process GO:0051402 142 0.022
developmental growth involved in morphogenesis GO:0060560 138 0.022
histone demethylation GO:0016577 13 0.022
fat cell differentiation GO:0045444 160 0.022
negative regulation of chromatin modification GO:1903309 19 0.022
negative regulation of neuron apoptotic process GO:0043524 92 0.022
positive regulation of cell death GO:0010942 224 0.022
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.021
regulation of hydrolase activity GO:0051336 246 0.021
multicellular organismal aging GO:0010259 24 0.021
heterochromatin organization GO:0070828 4 0.021
Fly
carbohydrate metabolic process GO:0005975 230 0.021
rna splicing GO:0008380 54 0.021
positive regulation of histone modification GO:0031058 28 0.021
Fly
development of primary male sexual characteristics GO:0046546 88 0.021
plasma lipoprotein particle clearance GO:0034381 13 0.021
spermatid differentiation GO:0048515 115 0.021
cellular ketone metabolic process GO:0042180 84 0.020
male gonad development GO:0008584 88 0.020
small gtpase mediated signal transduction GO:0007264 97 0.020
Worm
protein monoubiquitination GO:0006513 11 0.020
morphogenesis of embryonic epithelium GO:0016331 159 0.020
generation of precursor metabolites and energy GO:0006091 103 0.020
regulation of mapk cascade GO:0043408 248 0.020
cytoplasmic transport GO:0016482 234 0.019
protein deacetylation GO:0006476 32 0.019
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.019
heterochromatin assembly GO:0031507 2 0.019
Fly
dna templated transcription termination GO:0006353 4 0.019
protein maturation GO:0051604 176 0.019
regulation of ras protein signal transduction GO:0046578 114 0.019
Worm
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.019
t cell activation GO:0042110 289 0.019
epithelial to mesenchymal transition GO:0001837 47 0.019
female gonad development GO:0008585 71 0.019
cell fate commitment GO:0045165 210 0.019
scf dependent proteasomal ubiquitin dependent protein catabolic process GO:0031146 10 0.019
intracellular protein transport GO:0006886 204 0.019
posttranscriptional gene silencing GO:0016441 10 0.019
negative regulation of b cell activation GO:0050869 27 0.019
carboxylic acid biosynthetic process GO:0046394 86 0.018
positive regulation of transferase activity GO:0051347 167 0.018
nitrogen compound transport GO:0071705 271 0.018
male sex differentiation GO:0046661 109 0.018
epithelial cell proliferation GO:0050673 174 0.018
positive regulation of programmed cell death GO:0043068 218 0.018
regulation of response to dna damage stimulus GO:2001020 34 0.018
oogenesis GO:0048477 56 0.018
Worm
mesenchymal cell development GO:0014031 93 0.018
mrna stabilization GO:0048255 9 0.018
digestive system development GO:0055123 200 0.018
negative regulation of neuron death GO:1901215 98 0.018
negative regulation of lymphocyte activation GO:0051250 91 0.018
regulation of translation GO:0006417 71 0.017
transmission of nerve impulse GO:0019226 76 0.017
wnt signaling pathway GO:0016055 188 0.017
negative regulation of b cell differentiation GO:0045578 4 0.017
cellular response to organic cyclic compound GO:0071407 87 0.017
organic acid biosynthetic process GO:0016053 86 0.017
regulation of intracellular transport GO:0032386 159 0.017
purine nucleotide metabolic process GO:0006163 302 0.017
negative regulation of mrna processing GO:0050686 12 0.017
homeostasis of number of cells GO:0048872 210 0.017
glucan catabolic process GO:0009251 5 0.017
nuclear transport GO:0051169 139 0.017
neural precursor cell proliferation GO:0061351 121 0.017
nucleobase containing small molecule metabolic process GO:0055086 352 0.017
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.017
regulation of mrna processing GO:0050684 41 0.017
multicellular organism growth GO:0035264 161 0.017
Worm
ear development GO:0043583 200 0.017
inflammatory response GO:0006954 244 0.017
lipid transport GO:0006869 98 0.016
rna transport GO:0050658 18 0.016
regulation of endopeptidase activity GO:0052548 89 0.016
female sex differentiation GO:0046660 84 0.016
skin development GO:0043588 220 0.016
neural tube patterning GO:0021532 43 0.016
response to radiation GO:0009314 165 0.016
energy reserve metabolic process GO:0006112 39 0.016
positive regulation of organelle organization GO:0010638 128 0.016
Fly
regulation of lymphocyte differentiation GO:0045619 107 0.016
response to nutrient levels GO:0031667 109 0.016
meiotic cell cycle GO:0051321 122 0.016
development of primary female sexual characteristics GO:0046545 73 0.016
neuron death GO:0070997 154 0.016
locomotory behavior GO:0007626 195 0.016
epidermis development GO:0008544 187 0.016
regulation of membrane potential GO:0042391 192 0.016
phagocytosis GO:0006909 66 0.015
positive regulation of protein export from nucleus GO:0046827 4 0.015
methylation GO:0032259 134 0.015
Fly
oocyte construction GO:0007308 2 0.015
neuron projection guidance GO:0097485 141 0.015
internal peptidyl lysine acetylation GO:0018393 42 0.015
regulation of rna splicing GO:0043484 37 0.015
sensory organ boundary specification GO:0008052 1 0.015
positive regulation of protein kinase activity GO:0045860 144 0.015
regulation of neuron death GO:1901214 134 0.015
chemotaxis GO:0006935 247 0.015
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.015
lateral ventricle development GO:0021670 11 0.015
regulation of smoothened signaling pathway GO:0008589 58 0.015
regulation of chromatin binding GO:0035561 7 0.015
wound healing GO:0042060 157 0.015
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.015
blood vessel morphogenesis GO:0048514 285 0.015
nucleoside phosphate metabolic process GO:0006753 338 0.014
carbohydrate biosynthetic process GO:0016051 74 0.014
myeloid cell homeostasis GO:0002262 114 0.014
protein autophosphorylation GO:0046777 61 0.014
angiogenesis GO:0001525 201 0.014
dna dealkylation GO:0035510 11 0.014
b cell differentiation GO:0030183 78 0.014
glycogen catabolic process GO:0005980 5 0.014
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.014
regulation of epithelial cell proliferation GO:0050678 141 0.014
mitotic nuclear division GO:0007067 48 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
microtubule based process GO:0007017 236 0.014
fatty acid biosynthetic process GO:0006633 41 0.014
genitalia development GO:0048806 37 0.014
low density lipoprotein particle clearance GO:0034383 8 0.014
glucose metabolic process GO:0006006 92 0.014
tube formation GO:0035148 140 0.014
connective tissue development GO:0061448 179 0.014
tube closure GO:0060606 91 0.014
embryonic camera type eye development GO:0031076 36 0.013
white fat cell differentiation GO:0050872 15 0.013
negative regulation of histone methylation GO:0031061 10 0.013
positive regulation of mrna metabolic process GO:1903313 17 0.013
cation transmembrane transport GO:0098655 266 0.013
negative regulation of cell activation GO:0050866 111 0.013
placenta development GO:0001890 140 0.013
positive regulation of binding GO:0051099 49 0.013
regulation of mrna metabolic process GO:1903311 43 0.013
dna replication GO:0006260 52 0.013
protein processing GO:0016485 163 0.013
regulation of neuron apoptotic process GO:0043523 122 0.013
lipid biosynthetic process GO:0008610 179 0.013
protein targeting GO:0006605 143 0.013
positive regulation of chromatin binding GO:0035563 3 0.013
muscle cell differentiation GO:0042692 261 0.013
positive regulation of glycogen catabolic process GO:0045819 2 0.013
developmental maturation GO:0021700 193 0.013
chromatin remodeling GO:0006338 32 0.013
Fly
dna packaging GO:0006323 30 0.013
Fly
diencephalon development GO:0021536 63 0.013
response to alcohol GO:0097305 48 0.013
regulation of plasma lipoprotein particle levels GO:0097006 23 0.013
epithelial cell development GO:0002064 159 0.013
regulation of nucleocytoplasmic transport GO:0046822 73 0.013
regulation of proteolysis GO:0030162 164 0.013
monocarboxylic acid biosynthetic process GO:0072330 61 0.013
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.013
neural tube closure GO:0001843 90 0.013
mesenchymal cell differentiation GO:0048762 107 0.013
regulation of receptor biosynthetic process GO:0010869 2 0.013
regulation of glucose metabolic process GO:0010906 60 0.013
regulation of cellular ketone metabolic process GO:0010565 66 0.013
gland development GO:0048732 330 0.012
regulation of retinoic acid receptor signaling pathway GO:0048385 7 0.012
cell junction assembly GO:0034329 52 0.012
single fertilization GO:0007338 82 0.012
nucleotide catabolic process GO:0009166 217 0.012
primary neural tube formation GO:0014020 95 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
Worm
digestive tract morphogenesis GO:0048546 147 0.012
negative regulation of cellular protein metabolic process GO:0032269 247 0.012
action potential GO:0001508 78 0.012
gene silencing GO:0016458 38 0.012
Fly
histone h3 k4 methylation GO:0051568 23 0.012
purine containing compound metabolic process GO:0072521 311 0.012
regulation of actin filament based process GO:0032970 99 0.012
multicellular organismal signaling GO:0035637 91 0.012
mrna splicing via spliceosome GO:0000398 43 0.012
receptor biosynthetic process GO:0032800 3 0.012
regulation of mrna stability GO:0043488 23 0.012
posttranscriptional gene silencing by rna GO:0035194 10 0.012
transcription from rna polymerase iii promoter GO:0006383 3 0.012
skeletal system development GO:0001501 356 0.012
positive regulation of mapk cascade GO:0043410 170 0.011
nucleoside phosphate catabolic process GO:1901292 222 0.011
regulation of cellular amino acid metabolic process GO:0006521 5 0.011
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.011
regulation of exit from mitosis GO:0007096 1 0.011
response to light stimulus GO:0009416 135 0.011
rna localization GO:0006403 23 0.011
stem cell maintenance GO:0019827 130 0.011
positive regulation of rna splicing GO:0033120 12 0.011
regulation of adaptive immune response GO:0002819 90 0.011
viral process GO:0016032 41 0.011
negative regulation of microtubule polymerization GO:0031115 2 0.011
protein sumoylation GO:0016925 14 0.011
mitochondrion organization GO:0007005 134 0.011
mapk cascade GO:0000165 281 0.011
positive regulation of cellular component biogenesis GO:0044089 94 0.011
Fly
small molecule biosynthetic process GO:0044283 132 0.011
cellular response to hormone stimulus GO:0032870 150 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.011
germ cell proliferation GO:0036093 7 0.011
glycogen metabolic process GO:0005977 32 0.011
response to extracellular stimulus GO:0009991 127 0.011
lipid localization GO:0010876 126 0.011
regulation of protein kinase activity GO:0045859 232 0.011
cellular response to oxidative stress GO:0034599 76 0.011
negative regulation of peptidase activity GO:0010466 46 0.011
neural tube development GO:0021915 160 0.011
positive regulation of cellular amine metabolic process GO:0033240 5 0.011
positive regulation of hh target transcription factor activity GO:0007228 3 0.011
aromatic compound catabolic process GO:0019439 286 0.011
protein dna complex subunit organization GO:0071824 28 0.011
smoothened signaling pathway GO:0007224 105 0.011
leukocyte mediated immunity GO:0002443 174 0.011
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.010
mitotic chromosome condensation GO:0007076 1 0.010
purine nucleotide catabolic process GO:0006195 211 0.010
regulation of cysteine type endopeptidase activity GO:2000116 65 0.010
cell maturation GO:0048469 127 0.010
neural tube formation GO:0001841 108 0.010
positive regulation of histone h3 k9 methylation GO:0051574 4 0.010
Fly
cellular polysaccharide metabolic process GO:0044264 38 0.010
gene silencing by rna GO:0031047 19 0.010
dendrite development GO:0016358 115 0.010
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.010
nuclear division GO:0000280 158 0.010
positive regulation of retinoic acid receptor signaling pathway GO:0048386 3 0.010

Cbx3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.116
nervous system disease DOID:863 0 0.116
muscular disease DOID:0080000 0 0.013
musculoskeletal system disease DOID:17 0 0.013
muscle tissue disease DOID:66 0 0.013