IMP

Process View

Mus musculus

23 genes annotated in mouse

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demethylation

GO:0070988

The process of removing one or more methyl groups from a molecule.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "demethylation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "demethylation" (in gray)

Name	Description	Probability	Func Analog Organism
Rnf2	ring finger protein 2	0.958
Idi1	isopentenyl-diphosphate delta isomerase	0.626
Zfp292	zinc finger protein 292	0.550
Kdm1a	lysine (K)-specific demethylase 1A	0.507
Sin3a	transcriptional regulator, SIN3A (yeast)	0.433
Kdm2b	lysine (K)-specific demethylase 2B	0.340	Mouse Fly
Csnk2a1	casein kinase 2, alpha 1 polypeptide	0.276
Smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.250
Ctbp1	C-terminal binding protein 1	0.245
Sqle	squalene epoxidase	0.200
Trim28	tripartite motif-containing 28	0.196
Clk1	CDC-like kinase 1	0.161
Hmgcs1	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1	0.154
Bcor	BCL6 interacting corepressor	0.144
Ddx3y	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked	0.139
Gm5806	predicted gene 5806	0.132
Men1	multiple endocrine neoplasia 1	0.120
Cyp3a25	cytochrome P450, family 3, subfamily a, polypeptide 25	0.098	Human
Sc4mol	sterol-C4-methyl oxidase-like	0.096
Cbx5	chromobox homolog 5 (Drosophila HP1a)	0.091
Otc	ornithine transcarbamylase	0.090
Cbx8	chromobox homolog 8 (Drosophila Pc class)	0.087
Cbx3	chromobox homolog 3 (Drosophila HP1 gamma)	0.078
Nup62	nucleoporin 62	0.069
Clk4	CDC like kinase 4	0.065
Arid4b	AT rich interactive domain 4B (RBP1-like)	0.062
Rnps1	ribonucleic acid binding protein S1	0.061
Cbx1	chromobox homolog 1 (Drosophila HP1 beta)	0.052
Eif2s3y	eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked	0.049
Mbtd1	mbt domain containing 1	0.048
Hsd17b7	hydroxysteroid (17-beta) dehydrogenase 7	0.044
Cyp3a11	cytochrome P450, family 3, subfamily a, polypeptide 11	0.043	Human Rat
Nanog	Nanog homeobox	0.040
Ppm1g	protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform	0.040
Zfp654	zinc finger protein 654	0.038
Cdk2ap1	CDK2 (cyclin-dependent kinase 2)-associated protein 1	0.038
Trim24	tripartite motif-containing 24	0.037	Mouse
Hdac1	histone deacetylase 1	0.034
A930001N09Rik	RIKEN cDNA A930001N09 gene	0.031
Srm	spermidine synthase	0.029
Cyp3a16	cytochrome P450, family 3, subfamily a, polypeptide 16	0.028	Human Rat
Lin28a	lin-28 homolog A (C. elegans)	0.028
Ces2a	carboxylesterase 2A	0.027
Snrpa	small nuclear ribonucleoprotein polypeptide A	0.026
Ints3	integrator complex subunit 3	0.026
Nr1i2	nuclear receptor subfamily 1, group I, member 2	0.026
Ints5	integrator complex subunit 5	0.026
Uty	ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome	0.025
Cyp2c50	cytochrome P450, family 2, subfamily c, polypeptide 50	0.025
Jarid2	jumonji, AT rich interactive domain 2	0.025
Morf4l1	mortality factor 4 like 1	0.025
Zmym2	zinc finger, MYM-type 2	0.025
Kdm4c	lysine (K)-specific demethylase 4C	0.024	Human Yeast Fly
Sult1d1	sulfotransferase family 1D, member 1	0.024
Impdh2	inosine 5'-phosphate dehydrogenase 2	0.024
Pcgf2	polycomb group ring finger 2	0.024
Sult1b1	sulfotransferase family 1B, member 1	0.023
Cyp2a12	cytochrome P450, family 2, subfamily a, polypeptide 12	0.023
Cct3	chaperonin containing Tcp1, subunit 3 (gamma)	0.023
Tdg	thymine DNA glycosylase	0.023
Ubap2	ubiquitin-associated protein 2	0.023
Klhl24	kelch-like 24 (Drosophila)	0.023
Xrn1	5'-3' exoribonuclease 1	0.022
F9	coagulation factor IX	0.022
Cyp3a41b	cytochrome P450, family 3, subfamily a, polypeptide 41B	0.022	Human Rat
Eif4a2	eukaryotic translation initiation factor 4A2	0.022
Srsf4	serine/arginine-rich splicing factor 4	0.021
Arid1a	AT rich interactive domain 1A (SWI-like)	0.021
March7	membrane-associated ring finger (C3HC4) 7	0.021
Csnk2a2	casein kinase 2, alpha prime polypeptide	0.021
Sc5d	sterol-C5-desaturase (fungal ERG3, delta-5-desaturase) homolog (S. cerevisae)	0.021
Serpina1c	serine (or cysteine) peptidase inhibitor, clade A, member 1C	0.020
Avl9	AVL9 homolog (S. cerevisiase)	0.019
Ino80e	INO80 complex subunit E	0.019
Lss	lanosterol synthase	0.019
Mga	MAX gene associated	0.019
Zfc3h1	zinc finger, C3H1-type containing	0.019
Cyp2d10	cytochrome P450, family 2, subfamily d, polypeptide 10	0.019
Phc1	polyhomeotic-like 1 (Drosophila)	0.019
Ccnt2	cyclin T2	0.019
Cps1	carbamoyl-phosphate synthetase 1	0.018
Tex10	testis expressed gene 10	0.018
Fbl	fibrillarin	0.018
Ces1g	carboxylesterase 1G	0.018
Pom121	nuclear pore membrane protein 121	0.018
Cyp2c29	cytochrome P450, family 2, subfamily c, polypeptide 29	0.018
Ldlr	low density lipoprotein receptor	0.018
U2af2	U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2	0.018
Rlf	rearranged L-myc fusion sequence	0.018
Upf2	UPF2 regulator of nonsense transcripts homolog (yeast)	0.018
Prdm1	PR domain containing 1, with ZNF domain	0.018
Stard4	StAR-related lipid transfer (START) domain containing 4	0.018
Kti12	KTI12 homolog, chromatin associated (S. cerevisiae)	0.018
Fiz1	Flt3 interacting zinc finger protein 1	0.018
Slco1a1	solute carrier organic anion transporter family, member 1a1	0.018
Rbm14	RNA binding motif protein 14	0.017
Fbxo38	F-box protein 38	0.017
Bap1	Brca1 associated protein 1	0.017
Mogs	mannosyl-oligosaccharide glucosidase	0.017
Cul9	cullin 9	0.016
Usp10	ubiquitin specific peptidase 10	0.016
Dhx30	DEAH (Asp-Glu-Ala-His) box polypeptide 30	0.016
Xrcc1	X-ray repair complementing defective repair in Chinese hamster cells 1	0.016
Mup3	major urinary protein 3	0.016
Ugt2b34	UDP glucuronosyltransferase 2 family, polypeptide B34	0.016
Cyp2b9	cytochrome P450, family 2, subfamily b, polypeptide 9	0.016
Usp21	ubiquitin specific peptidase 21	0.016
Chd2	chromodomain helicase DNA binding protein 2	0.016
Ccng2	cyclin G2	0.016
Carm1	coactivator-associated arginine methyltransferase 1	0.015
Eif3c	eukaryotic translation initiation factor 3, subunit C	0.015
Ctps	cytidine 5'-triphosphate synthase	0.015
Yaf2	YY1 associated factor 2	0.015
Clk3	CDC-like kinase 3	0.015
Skp1a	S-phase kinase-associated protein 1A	0.015
Vmn1r51	vomeronasal 1 receptor 51	0.015
Puf60	poly-U binding splicing factor 60	0.015
Mta2	metastasis-associated gene family, member 2	0.015
Scrib	scribbled homolog (Drosophila)	0.015
Dnajb1	DnaJ (Hsp40) homolog, subfamily B, member 1	0.015
Acat2	acetyl-Coenzyme A acetyltransferase 2	0.015
Psat1	phosphoserine aminotransferase 1	0.014
Bmi1	Bmi1 polycomb ring finger oncogene	0.014
Cyp3a44	cytochrome P450, family 3, subfamily a, polypeptide 44	0.014	Human Rat
Aff4	AF4/FMR2 family, member 4	0.014
Lin28b	lin-28 homolog B (C. elegans)	0.014
Arid4a	AT rich interactive domain 4A (RBP1-like)	0.014
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.014
Dbx1	developing brain homeobox 1	0.014
Ints6	integrator complex subunit 6	0.014
Oxsm	3-oxoacyl-ACP synthase, mitochondrial	0.014
Wdr5	WD repeat domain 5	0.013
Bche	butyrylcholinesterase	0.013
Paip2	polyadenylate-binding protein-interacting protein 2	0.013
Ddx39b	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B	0.013
Ces3a	carboxylesterase 3A	0.013
Kdm5d	lysine (K)-specific demethylase 5D	0.013	Human Mouse Fly
Hmgcr	3-hydroxy-3-methylglutaryl-Coenzyme A reductase	0.013
Alkbh1	alkB, alkylation repair homolog 1 (E. coli)	0.013
Maml1	mastermind like 1 (Drosophila)	0.013
Arid1b	AT rich interactive domain 1B (SWI-like)	0.013
Kdm3a	lysine (K)-specific demethylase 3A	0.013	Human
Zfand6	zinc finger, AN1-type domain 6	0.013
Tdgf1	teratocarcinoma-derived growth factor 1	0.013
Fmo5	flavin containing monooxygenase 5	0.013
Pck1	phosphoenolpyruvate carboxykinase 1, cytosolic	0.013
Sval1	seminal vesicle antigen-like 1	0.013
Rev3l	REV3-like, catalytic subunit of DNA polymerase zeta RAD54 like (S. cerevisiae)	0.012
AW549877	expressed sequence AW549877	0.012
Rxrb	retinoid X receptor beta	0.012
Phc2	polyhomeotic-like 2 (Drosophila)	0.012
Phf21a	PHD finger protein 21A	0.012
Rybp	RING1 and YY1 binding protein	0.012
Senp3	SUMO/sentrin specific peptidase 3	0.012
Epc1	enhancer of polycomb homolog 1 (Drosophila)	0.012
Tab3	TGF-beta activated kinase 1/MAP3K7 binding protein 3	0.012
Pogz	pogo transposable element with ZNF domain	0.012
Cyp2c37	cytochrome P450, family 2. subfamily c, polypeptide 37	0.012
Cyp2b10	cytochrome P450, family 2, subfamily b, polypeptide 10	0.012
Rabgap1	RAB GTPase activating protein 1	0.012
Med13l	mediator complex subunit 13-like	0.012
Vmn1r45	vomeronasal 1 receptor 45	0.012
Rsbn1	rosbin, round spermatid basic protein 1	0.012
Ncoa5	nuclear receptor coactivator 5	0.012
Zmym5	zinc finger, MYM-type 5	0.012
Pcmtd2	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2	0.012
Elovl3	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3	0.012
Chfr	checkpoint with forkhead and ring finger domains	0.012
Trip12	thyroid hormone receptor interactor 12	0.012
Akr1c6	aldo-keto reductase family 1, member C6	0.011
Nr1i3	nuclear receptor subfamily 1, group I, member 3	0.011
Cyp2c38	cytochrome P450, family 2, subfamily c, polypeptide 38	0.011
Nop2	NOP2 nucleolar protein homolog (yeast)	0.011
Dmtf1	cyclin D binding myb-like transcription factor 1	0.011
Ugt2b5	UDP glucuronosyltransferase 2 family, polypeptide B5	0.011
Wdr26	WD repeat domain 26	0.011
Ruvbl2	RuvB-like protein 2	0.011
Slc22a1	solute carrier family 22 (organic cation transporter), member 1	0.011
Lcor	ligand dependent nuclear receptor corepressor	0.011
Aldob	aldolase B, fructose-bisphosphate	0.011
Apoc3	apolipoprotein C-III	0.011
Atp11b	ATPase, class VI, type 11B	0.011
Hist1h1e	histone cluster 1, H1e	0.011
Ring1	ring finger protein 1	0.011
4833420G17Rik	RIKEN cDNA 4833420G17 gene	0.010
Cad	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	0.010
Atf7ip	activating transcription factor 7 interacting protein	0.010
Phkg1	phosphorylase kinase gamma 1	0.010
Apob	apolipoprotein B	0.010
Fbxl3	F-box and leucine-rich repeat protein 3	0.010
Irf8	interferon regulatory factor 8	0.010
Gucy2c	guanylate cyclase 2c	0.010
Serpina6	serine (or cysteine) peptidase inhibitor, clade A, member 6	0.010
Dnmt1	DNA methyltransferase (cytosine-5) 1	0.010
Mvd	mevalonate (diphospho) decarboxylase	0.010
Vps72	vacuolar protein sorting 72 (yeast)	0.010
Cyp3a13	cytochrome P450, family 3, subfamily a, polypeptide 13	0.010	Human
Bnip3l	BCL2/adenovirus E1B interacting protein 3-like	0.010
Chtf8	CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae)	0.010
Brwd1	bromodomain and WD repeat domain containing 1	0.010
Rdh11	retinol dehydrogenase 11	0.010
Ptk6	PTK6 protein tyrosine kinase 6	0.010
Zfp42	zinc finger protein 42	0.010