|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.938
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.886
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.880
|
Fly |
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.876
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.853
|
Fly |
|
|
negative regulation of cell cycle arrest
|
GO:0071157 |
1 |
0.840
|
Human |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.825
|
|
|
|
segmentation
|
GO:0035282 |
93 |
0.816
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.813
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
53 |
0.798
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.797
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.783
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.780
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.752
|
Mouse |
|
|
pole plasm assembly
|
GO:0007315 |
2 |
0.740
|
|
|
|
regulation of mammary gland epithelial cell proliferation
|
GO:0033599 |
12 |
0.730
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.723
|
|
|
|
jak stat cascade
|
GO:0007259 |
42 |
0.720
|
Fly |
|
|
notch signaling pathway
|
GO:0007219 |
71 |
0.695
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.657
|
Mouse |
|
|
positive regulation of g2 m transition of mitotic cell cycle
|
GO:0010971 |
5 |
0.652
|
Human |
|
|
hematopoietic stem cell differentiation
|
GO:0060218 |
8 |
0.651
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.651
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
13 |
0.648
|
|
|
|
mammary gland epithelial cell proliferation
|
GO:0033598 |
24 |
0.640
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.638
|
Mouse |
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.633
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.621
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.605
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.599
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.592
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.589
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.581
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.579
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.578
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
35 |
0.573
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.567
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.563
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.555
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.554
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
35 |
0.547
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.542
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.541
|
|
|
|
oocyte anterior posterior axis specification
|
GO:0007314 |
2 |
0.535
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.535
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.531
|
Human |
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.524
|
Fly |
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.520
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.501
|
|
|
|
re entry into mitotic cell cycle
|
GO:0000320 |
3 |
0.497
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.495
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.474
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.470
|
|
|
|
cell aging
|
GO:0007569 |
35 |
0.467
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.465
|
Human |
|
|
positive regulation of cell cycle g1 s phase transition
|
GO:1902808 |
9 |
0.462
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
57 |
0.459
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.459
|
|
|
|
lactation
|
GO:0007595 |
25 |
0.456
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.452
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.435
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.433
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.429
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
16 |
0.420
|
Human |
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.418
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.413
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.411
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.409
|
|
|
|
cellular response to topologically incorrect protein
|
GO:0035967 |
25 |
0.405
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.404
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
51 |
0.404
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.403
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.398
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.396
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
33 |
0.396
|
Fly |
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.393
|
Fly |
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.387
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
68 |
0.387
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.386
|
Human |
|
|
circadian regulation of gene expression
|
GO:0032922 |
48 |
0.383
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.382
|
|
|
|
positive regulation of mammary gland epithelial cell proliferation
|
GO:0033601 |
5 |
0.382
|
|
|
|
activation of adenylate cyclase activity
|
GO:0007190 |
4 |
0.371
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.369
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.369
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.368
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.367
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.364
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.358
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.358
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.357
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.356
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.355
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
35 |
0.353
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.352
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.351
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.350
|
Human |
|
|
oocyte construction
|
GO:0007308 |
2 |
0.349
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.349
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.345
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.344
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.344
|
|
|
|
canonical wnt signaling pathway involved in negative regulation of apoptotic process
|
GO:0044336 |
4 |
0.334
|
|
|
|
response to testosterone
|
GO:0033574 |
3 |
0.333
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.331
|
Human |
|
|
digestive tract development
|
GO:0048565 |
190 |
0.330
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.328
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.328
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.320
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.315
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.314
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.310
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.308
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.306
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.302
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.301
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.296
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.294
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.290
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.288
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.288
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.288
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.288
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.287
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.286
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.286
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.280
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
86 |
0.278
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.278
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.277
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.277
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.276
|
Rat |
|
|
cell division
|
GO:0051301 |
120 |
0.275
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.274
|
|
|
|
cell cycle arrest
|
GO:0007050 |
37 |
0.273
|
Human |
|
|
cellular response to antibiotic
|
GO:0071236 |
4 |
0.272
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.270
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.265
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.264
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.261
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.260
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.258
|
Mouse |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.256
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.253
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
61 |
0.249
|
Human |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.246
|
|
|
|
maternal determination of anterior posterior axis embryo
|
GO:0008358 |
2 |
0.245
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.245
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.244
|
|
|
|
regulation of fibroblast proliferation
|
GO:0048145 |
34 |
0.243
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.243
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.242
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.240
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.237
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.235
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.233
|
Human Rat |
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.233
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.232
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.231
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.229
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.227
|
|
|
|
positive regulation of cell cycle phase transition
|
GO:1901989 |
17 |
0.227
|
Human |
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.226
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
77 |
0.226
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.225
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.223
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.221
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.220
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
86 |
0.219
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.214
|
Zebrafish |
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.214
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.214
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.212
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.212
|
Human |
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.212
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.211
|
|
|
|
positive regulation of fibroblast proliferation
|
GO:0048146 |
20 |
0.210
|
|
|
|
genitalia development
|
GO:0048806 |
37 |
0.210
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.209
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.209
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.207
|
|
|
|
cellular senescence
|
GO:0090398 |
11 |
0.205
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.202
|
|
|
|
cytokinesis
|
GO:0000910 |
17 |
0.200
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.199
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.199
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.198
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.197
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.197
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.196
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.195
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.195
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.194
|
|
|
|
fibroblast proliferation
|
GO:0048144 |
35 |
0.193
|
|
|
|
regulation of cellular senescence
|
GO:2000772 |
6 |
0.191
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.191
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.191
|
|
|
|
positive regulation of camp metabolic process
|
GO:0030816 |
19 |
0.189
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.188
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.187
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.186
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.185
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.184
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.180
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.179
|
|
|
|
positive regulation of g1 s transition of mitotic cell cycle
|
GO:1900087 |
9 |
0.179
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
48 |
0.179
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.178
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.178
|
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
30 |
0.177
|
|
|
|
negative regulation of osteoblast differentiation
|
GO:0045668 |
30 |
0.176
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.173
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.171
|
|
|
|
limbic system development
|
GO:0021761 |
72 |
0.171
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.169
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.168
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
77 |
0.167
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.166
|
Rat |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.165
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.165
|
Rat |
|
|
male gamete generation
|
GO:0048232 |
285 |
0.165
|
|
|
|
regulation of microtubule polymerization
|
GO:0031113 |
7 |
0.163
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.163
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.159
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.159
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.159
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.155
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.154
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.154
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.153
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
73 |
0.152
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.151
|
|
|
|
mammary gland alveolus development
|
GO:0060749 |
22 |
0.150
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.150
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.149
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.149
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.148
|
|
|
|
hindbrain development
|
GO:0030902 |
128 |
0.148
|
|
|
|
cellular response to gamma radiation
|
GO:0071480 |
4 |
0.148
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.148
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.147
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.147
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.146
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.146
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.143
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.142
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.140
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.139
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
34 |
0.138
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.138
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.137
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.133
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.131
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
64 |
0.131
|
|
|
|
regulation of nuclear cell cycle dna replication
|
GO:0033262 |
2 |
0.131
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.130
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.130
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.130
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
59 |
0.129
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.129
|
|
|
|
regulation of g2 m transition of mitotic cell cycle
|
GO:0010389 |
10 |
0.129
|
Human |
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.128
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.128
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.127
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.126
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.126
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
65 |
0.126
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.125
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
31 |
0.125
|
|
|
|
gene silencing
|
GO:0016458 |
38 |
0.125
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
59 |
0.124
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.123
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.123
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
73 |
0.123
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.123
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.122
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.122
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.121
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.120
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.119
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.119
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.119
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.118
|
|
|
|
schwann cell proliferation
|
GO:0014010 |
2 |
0.118
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.118
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.117
|
|
|
|
oocyte differentiation
|
GO:0009994 |
35 |
0.116
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.116
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.116
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.116
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.115
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.114
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.114
|
Rat |
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.114
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.114
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.114
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.113
|
|
|
|
body fluid secretion
|
GO:0007589 |
53 |
0.113
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.112
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.112
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.111
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902043 |
13 |
0.111
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.110
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
59 |
0.110
|
|
|
|
carbon catabolite activation of transcription
|
GO:0045991 |
4 |
0.110
|
|
|
|
response to alcohol
|
GO:0097305 |
48 |
0.109
|
Rat |
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.109
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.109
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.108
|
|
|
|
signal transduction involved in dna integrity checkpoint
|
GO:0072401 |
3 |
0.108
|
|
|
|
localization within membrane
|
GO:0051668 |
4 |
0.108
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
82 |
0.108
|
|
|
|
response to antibiotic
|
GO:0046677 |
11 |
0.107
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.106
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.106
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
41 |
0.105
|
Human |
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.105
|
|
|
|
microtubule cytoskeleton organization involved in mitosis
|
GO:1902850 |
4 |
0.104
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.104
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
59 |
0.103
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.103
|
|
|
|
limb development
|
GO:0060173 |
166 |
0.103
|
|
|
|
mrna metabolic process
|
GO:0016071 |
84 |
0.103
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.102
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
52 |
0.101
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.101
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
36 |
0.101
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.100
|
|
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
26 |
0.099
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.099
|
Rat |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.098
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
34 |
0.098
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.098
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.097
|
Rat |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.097
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.097
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.097
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.096
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.096
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.096
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.095
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
78 |
0.095
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.095
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.094
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.094
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.094
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.093
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.093
|
Human |
|
|
mitotic cell cycle arrest
|
GO:0071850 |
4 |
0.092
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.091
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.091
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.091
|
|
|
|
oocyte development
|
GO:0048599 |
33 |
0.091
|
|
|
|
negative regulation of cellular senescence
|
GO:2000773 |
3 |
0.090
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.090
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.089
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.089
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.089
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.089
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.088
|
|
|
|
negative regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0045736 |
9 |
0.087
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.087
|
|
|
|
response to unfolded protein
|
GO:0006986 |
21 |
0.086
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.086
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.086
|
|
|
|
response to drug
|
GO:0042493 |
75 |
0.086
|
Human Rat |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.085
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
1 |
0.085
|
|
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
25 |
0.084
|
|
|
|
positive regulation of chromosome segregation
|
GO:0051984 |
4 |
0.084
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
40 |
0.084
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.084
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.084
|
|
|
|
positive regulation of transcription by galactose
|
GO:0000411 |
1 |
0.083
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.083
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.083
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
45 |
0.083
|
Human |
|
|
liver development
|
GO:0001889 |
66 |
0.082
|
Rat |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.082
|
Human |
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.081
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.081
|
|
|
|
negative regulation of ossification
|
GO:0030279 |
49 |
0.081
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.081
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.081
|
|
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
77 |
0.081
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.080
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.080
|
|
|
|
response to metal ion
|
GO:0010038 |
47 |
0.080
|
Rat |
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.079
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.077
|
|
|
|
dna replication
|
GO:0006260 |
52 |
0.077
|
|
|
|
cellular response to radiation
|
GO:0071478 |
28 |
0.076
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
45 |
0.076
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
81 |
0.076
|
|
|
|
dna catabolic process
|
GO:0006308 |
19 |
0.076
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
19 |
0.076
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
61 |
0.076
|
|
|
|
negative regulation of jun kinase activity
|
GO:0043508 |
9 |
0.075
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
34 |
0.075
|
|
|
|
metencephalon development
|
GO:0022037 |
89 |
0.075
|
|
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
20 |
0.074
|
Human |
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.074
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.073
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.073
|
|
|
|
polarity specification of proximal distal axis
|
GO:0010085 |
2 |
0.073
|
|
|
|
positive regulation of mitochondrion organization
|
GO:0010822 |
17 |
0.073
|
|
|
|
signal transduction involved in mitotic dna damage checkpoint
|
GO:1902402 |
3 |
0.073
|
|
|
|
hippocampus development
|
GO:0021766 |
52 |
0.073
|
|
|
|
regulation of cell cycle g2 m phase transition
|
GO:1902749 |
10 |
0.073
|
Human |
|
|
intracellular mrna localization
|
GO:0008298 |
4 |
0.073
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.072
|
|
|
|
camp metabolic process
|
GO:0046058 |
40 |
0.072
|
|
|
|
formation of radial glial scaffolds
|
GO:0021943 |
4 |
0.072
|
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
20 |
0.072
|
Human |
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.070
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.070
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.069
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.069
|
|
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
24 |
0.069
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.069
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.069
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.069
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.069
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
40 |
0.068
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.068
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.068
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
34 |
0.068
|
|
|
|
body morphogenesis
|
GO:0010171 |
45 |
0.067
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
54 |
0.067
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.067
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.067
|
|
|
|
positive regulation of microtubule polymerization
|
GO:0031116 |
3 |
0.067
|
|
|
|
positive regulation of protein export from nucleus
|
GO:0046827 |
4 |
0.066
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
72 |
0.066
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.066
|
|
|
|
negative regulation of organ growth
|
GO:0046621 |
17 |
0.066
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.066
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.065
|
Worm |
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
23 |
0.065
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.065
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
47 |
0.065
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.065
|
|
|
|
regulation of microtubule polymerization or depolymerization
|
GO:0031110 |
20 |
0.065
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.065
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.065
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.064
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.064
|
|
|
|
defecation
|
GO:0030421 |
1 |
0.064
|
|
|
|
forebrain radial glial cell differentiation
|
GO:0021861 |
4 |
0.063
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.063
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.063
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.063
|
|
|
|
negative regulation of mammary gland epithelial cell proliferation
|
GO:0033600 |
3 |
0.063
|
|
|
|
mammary gland lobule development
|
GO:0061377 |
22 |
0.063
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.062
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.062
|
Human |
|
|
regulation of glial cell differentiation
|
GO:0045685 |
41 |
0.062
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.062
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.062
|
|
|
|
signal transduction involved in dna damage checkpoint
|
GO:0072422 |
3 |
0.062
|
|
|
|
response to uv
|
GO:0009411 |
44 |
0.061
|
Human |
|
|
inflammatory response
|
GO:0006954 |
244 |
0.061
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.061
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.061
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.060
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.060
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
28 |
0.060
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.060
|
|
|
|
carbon catabolite regulation of transcription
|
GO:0045990 |
4 |
0.060
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
37 |
0.060
|
|
|
|
canonical wnt signaling pathway involved in positive regulation of apoptotic process
|
GO:0044337 |
3 |
0.059
|
|
|
|
sensory perception of sound
|
GO:0007605 |
97 |
0.059
|
|
|
|
protein complex disassembly
|
GO:0043241 |
40 |
0.059
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
19 |
0.059
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.059
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.059
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
42 |
0.059
|
Rat |
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.059
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
31 |
0.059
|
Human |
|
|
er nucleus signaling pathway
|
GO:0006984 |
27 |
0.058
|
|
|
|
cell junction assembly
|
GO:0034329 |
52 |
0.058
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.058
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.058
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.058
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.058
|
|
