|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.979
|
Mouse |
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.958
|
Mouse |
|
|
innate immune response
|
GO:0045087 |
157 |
0.950
|
Mouse |
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.950
|
Mouse |
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.936
|
Mouse |
|
|
stimulatory c type lectin receptor signaling pathway
|
GO:0002223 |
2 |
0.932
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.929
|
Mouse |
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.927
|
Mouse |
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.904
|
Mouse |
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.891
|
Mouse |
|
|
activation of immune response
|
GO:0002253 |
138 |
0.880
|
Mouse |
|
|
immune effector process
|
GO:0002252 |
321 |
0.880
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.851
|
Mouse |
|
|
b cell activation
|
GO:0042113 |
161 |
0.828
|
|
|
|
helper t cell chemotaxis
|
GO:0035704 |
1 |
0.821
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.821
|
Mouse |
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.781
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.768
|
Mouse |
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.766
|
|
|
|
cell surface pattern recognition receptor signaling pathway
|
GO:0002752 |
2 |
0.760
|
Mouse |
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.760
|
|
|
|
innate immune response activating cell surface receptor signaling pathway
|
GO:0002220 |
4 |
0.757
|
Mouse |
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.750
|
Mouse |
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.742
|
Mouse |
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.738
|
Mouse |
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.730
|
|
|
|
eosinophil activation
|
GO:0043307 |
1 |
0.696
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.685
|
Mouse |
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.671
|
Mouse |
|
|
positive regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000451 |
2 |
0.639
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
31 |
0.639
|
Mouse |
|
|
positive regulation of immunological synapse formation
|
GO:2000522 |
1 |
0.636
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.627
|
Mouse |
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.622
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.596
|
Mouse |
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.587
|
|
|
|
positive regulation of t cell receptor signaling pathway
|
GO:0050862 |
4 |
0.583
|
|
|
|
t helper 17 cell chemotaxis
|
GO:0035705 |
1 |
0.553
|
|
|
|
regulation of t cell costimulation
|
GO:2000523 |
2 |
0.548
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.547
|
|
|
|
regulation of monocyte extravasation
|
GO:2000437 |
2 |
0.522
|
|
|
|
positive regulation of t cell costimulation
|
GO:2000525 |
2 |
0.520
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.514
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.509
|
Mouse |
|
|
positive regulation of t cell extravasation
|
GO:2000409 |
2 |
0.507
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.505
|
Mouse |
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.501
|
|
|
|
dendritic cell differentiation
|
GO:0097028 |
26 |
0.501
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.497
|
|
|
|
toxin catabolic process
|
GO:0009407 |
1 |
0.491
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.485
|
Mouse |
|
|
eosinophil degranulation
|
GO:0043308 |
1 |
0.482
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.481
|
|
|
|
chemokine mediated signaling pathway
|
GO:0070098 |
17 |
0.478
|
|
|
|
negative regulation of eosinophil degranulation
|
GO:0043310 |
1 |
0.474
|
|
|
|
cd8 positive alpha beta t cell extravasation
|
GO:0035697 |
3 |
0.473
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.463
|
|
|
|
positive regulation of tumor necrosis factor production
|
GO:0032760 |
30 |
0.453
|
Mouse |
|
|
membrane organization
|
GO:0061024 |
245 |
0.451
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.435
|
|
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
16 |
0.418
|
|
|
|
monocyte extravasation
|
GO:0035696 |
2 |
0.416
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.414
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.413
|
|
|
|
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation
|
GO:2000526 |
1 |
0.411
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.405
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.404
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.403
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.395
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.392
|
|
|
|
regulation of tumor necrosis factor biosynthetic process
|
GO:0042534 |
10 |
0.390
|
Mouse |
|
|
chemotaxis
|
GO:0006935 |
247 |
0.382
|
|
|
|
response to molecule of fungal origin
|
GO:0002238 |
4 |
0.380
|
Mouse |
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.370
|
Mouse |
|
|
regulation of eosinophil degranulation
|
GO:0043309 |
1 |
0.360
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.357
|
Mouse |
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.356
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.356
|
Mouse |
|
|
regulation of t cell extravasation
|
GO:2000407 |
3 |
0.353
|
|
|
|
t cell extravasation
|
GO:0072683 |
4 |
0.351
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.350
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.350
|
Mouse |
|
|
hematopoietic stem cell migration
|
GO:0035701 |
1 |
0.343
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.341
|
|
|
|
positive regulation of dendritic cell chemotaxis
|
GO:2000510 |
1 |
0.332
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.331
|
Mouse |
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.312
|
Mouse |
|
|
eosinophil activation involved in immune response
|
GO:0002278 |
1 |
0.312
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.306
|
Mouse |
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.305
|
Mouse |
|
|
mature dendritic cell differentiation
|
GO:0097029 |
3 |
0.300
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.297
|
Mouse |
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.291
|
Mouse |
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.290
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.288
|
|
|
|
immune complex clearance by monocytes and macrophages
|
GO:0002436 |
2 |
0.282
|
|
|
|
eosinophil mediated immunity
|
GO:0002447 |
1 |
0.278
|
|
|
|
detection of biotic stimulus
|
GO:0009595 |
10 |
0.276
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.276
|
Mouse |
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.274
|
Mouse |
|
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.273
|
Mouse |
|
|
toll like receptor 7 signaling pathway
|
GO:0034154 |
4 |
0.266
|
|
|
|
positive regulation of monocyte extravasation
|
GO:2000439 |
1 |
0.265
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.265
|
|
|
|
myeloid dendritic cell activation
|
GO:0001773 |
25 |
0.263
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.263
|
Mouse |
|
|
regulation of immunological synapse formation
|
GO:2000520 |
2 |
0.256
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.254
|
|
|
|
microglial cell activation involved in immune response
|
GO:0002282 |
1 |
0.252
|
|
|
|
regulation of immune complex clearance by monocytes and macrophages
|
GO:0090264 |
2 |
0.251
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.246
|
Mouse |
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.244
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.244
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.243
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.241
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.233
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.233
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.232
|
Mouse |
|
|
positive regulation of interferon alpha production
|
GO:0032727 |
4 |
0.227
|
Mouse |
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.224
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.223
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.218
|
Mouse |
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.218
|
Mouse |
|
|
microglial cell activation
|
GO:0001774 |
3 |
0.217
|
|
|
|
negative regulation of leukocyte mediated immunity
|
GO:0002704 |
29 |
0.217
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.217
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.217
|
|
|
|
cellular response to molecule of fungal origin
|
GO:0071226 |
2 |
0.214
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.214
|
Mouse |
|
|
regulation of hematopoietic stem cell migration
|
GO:2000471 |
1 |
0.214
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
47 |
0.212
|
|
|
|
positive regulation of natural killer cell mediated immunity
|
GO:0002717 |
16 |
0.207
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.206
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.205
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.203
|
Mouse |
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.202
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.201
|
Mouse |
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.201
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.198
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.195
|
Mouse |
|
|
interferon beta biosynthetic process
|
GO:0045350 |
4 |
0.195
|
Mouse |
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.194
|
Mouse |
|
|
protein secretion
|
GO:0009306 |
111 |
0.191
|
Mouse |
|
|
detection of other organism
|
GO:0098543 |
8 |
0.189
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.188
|
|
|
|
oligodendrocyte differentiation
|
GO:0048709 |
53 |
0.188
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.187
|
|
|
|
regulation of mast cell activation involved in immune response
|
GO:0033006 |
17 |
0.186
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.185
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.182
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.181
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.180
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.179
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.179
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.177
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.174
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.173
|
Mouse |
|
|
regulated secretory pathway
|
GO:0045055 |
32 |
0.173
|
|
|
|
purinergic nucleotide receptor signaling pathway
|
GO:0035590 |
3 |
0.173
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.171
|
Mouse |
|
|
positive regulation of leukocyte mediated cytotoxicity
|
GO:0001912 |
31 |
0.169
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.167
|
|
|
|
positive regulation of lymphocyte migration
|
GO:2000403 |
11 |
0.166
|
|
|
|
mast cell activation involved in immune response
|
GO:0002279 |
20 |
0.165
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.163
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.163
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.163
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.160
|
|
|
|
positive regulation of hematopoietic stem cell migration
|
GO:2000473 |
1 |
0.159
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.158
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.158
|
Mouse |
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.157
|
|
|
|
immune complex clearance
|
GO:0002434 |
2 |
0.155
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.155
|
Mouse |
|
|
positive regulation of immune complex clearance by monocytes and macrophages
|
GO:0090265 |
2 |
0.152
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.151
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.150
|
Mouse |
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.148
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.146
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.145
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.144
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.143
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.143
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.141
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.140
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.140
|
Mouse |
|
|
regulation of interleukin 1 production
|
GO:0032652 |
26 |
0.139
|
Mouse |
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.138
|
Mouse |
|
|
regulation of toll like receptor signaling pathway
|
GO:0034121 |
20 |
0.137
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.136
|
Mouse |
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.136
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.133
|
Mouse |
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.131
|
Mouse |
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.131
|
Mouse |
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.131
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.130
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.130
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.128
|
Mouse |
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.127
|
Mouse |
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.126
|
Mouse |
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.126
|
Mouse |
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.125
|
|
|
|
regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000449 |
3 |
0.125
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.123
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.123
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.122
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.122
|
|
|
|
regulation of type 2 immune response
|
GO:0002828 |
18 |
0.122
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.121
|
Mouse |
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.121
|
Mouse |
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.121
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.121
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.119
|
|
|
|
positive regulation of interleukin 18 production
|
GO:0032741 |
2 |
0.119
|
Mouse |
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.117
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.116
|
|
|
|
regulation of t helper 1 type immune response
|
GO:0002825 |
17 |
0.116
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.116
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.115
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.114
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.113
|
Mouse |
|
|
natural killer cell activation
|
GO:0030101 |
44 |
0.112
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.110
|
|
|
|
response to interferon gamma
|
GO:0034341 |
34 |
0.109
|
|
|
|
regulation of interferon beta biosynthetic process
|
GO:0045357 |
4 |
0.107
|
Mouse |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.106
|
Mouse |
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.105
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.102
|
|
|
|
negative regulation of exocytosis
|
GO:0045920 |
12 |
0.102
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.102
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.101
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.101
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.101
|
Mouse |
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.100
|
Mouse |
|
|
regulation of natural killer cell mediated immunity
|
GO:0002715 |
19 |
0.100
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.100
|
Mouse |
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.100
|
|
|
|
mast cell degranulation
|
GO:0043303 |
19 |
0.099
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.099
|
|
|
|
regulation of antigen processing and presentation
|
GO:0002577 |
10 |
0.098
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.098
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.098
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.096
|
Mouse |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.095
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.095
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.094
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.094
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.094
|
|
|
|
forebrain cell migration
|
GO:0021885 |
58 |
0.093
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.093
|
Mouse |
|
|
regulation of monocyte chemotaxis
|
GO:0090025 |
3 |
0.093
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.092
|
|
|
|
axon ensheathment
|
GO:0008366 |
76 |
0.091
|
|
|
|
regulation of gliogenesis
|
GO:0014013 |
50 |
0.090
|
|
|
|
interleukin 1 secretion
|
GO:0050701 |
16 |
0.090
|
|
|
|
regulation of dendritic cell chemotaxis
|
GO:2000508 |
1 |
0.089
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.087
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.087
|
Mouse |
|
|
regulation of toll like receptor 4 signaling pathway
|
GO:0034143 |
4 |
0.087
|
|
|
|
positive regulation of glial cell differentiation
|
GO:0045687 |
21 |
0.086
|
|
|
|
detection of external biotic stimulus
|
GO:0098581 |
9 |
0.086
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.086
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.085
|
Mouse |
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.085
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.085
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.084
|
|
|
|
regulation of phagocytosis
|
GO:0050764 |
33 |
0.084
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
39 |
0.084
|
|
|
|
telencephalon cell migration
|
GO:0022029 |
55 |
0.083
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.083
|
|
|
|
inflammatory response to antigenic stimulus
|
GO:0002437 |
30 |
0.083
|
|
|
|
nitric oxide metabolic process
|
GO:0046209 |
25 |
0.083
|
Mouse |
|
|
negative regulation of b cell activation
|
GO:0050869 |
27 |
0.081
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.081
|
|
|
|
bone resorption
|
GO:0045453 |
38 |
0.081
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.080
|
|
|
|
natural killer cell mediated cytotoxicity
|
GO:0042267 |
29 |
0.080
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.080
|
Mouse |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.080
|
|
|
|
positive regulation of oligodendrocyte differentiation
|
GO:0048714 |
9 |
0.080
|
|
|
|
positive regulation of neutrophil chemotaxis
|
GO:0090023 |
12 |
0.079
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.079
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.078
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.078
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.078
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.076
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.076
|
|
|
|
macrophage chemotaxis
|
GO:0048246 |
14 |
0.076
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.076
|
Mouse |
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.076
|
Mouse |
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.075
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.075
|
Mouse |
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.074
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.074
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.074
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.074
|
Mouse |
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.073
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.072
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.072
|
Mouse |
|
|
regulation of thymocyte migration
|
GO:2000410 |
2 |
0.071
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.071
|
|
|
|
lymphocyte costimulation
|
GO:0031294 |
15 |
0.071
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.071
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.070
|
|
|
|
interleukin 12 secretion
|
GO:0072610 |
3 |
0.070
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.070
|
|
|
|
regulation of cell killing
|
GO:0031341 |
40 |
0.069
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.069
|
|
|
|
regulation of granulocyte chemotaxis
|
GO:0071622 |
17 |
0.068
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.068
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.068
|
Mouse |
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.068
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.067
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.067
|
Mouse |
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.067
|
Mouse |
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.066
|
Mouse |
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.066
|
|
|
|
positive regulation of natural killer cell mediated cytotoxicity
|
GO:0045954 |
16 |
0.066
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.065
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.065
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.065
|
|
|
|
positive regulation of tumor necrosis factor biosynthetic process
|
GO:0042535 |
8 |
0.064
|
Mouse |
|
|
gliogenesis
|
GO:0042063 |
141 |
0.064
|
|
|
|
cell recognition
|
GO:0008037 |
83 |
0.064
|
|
|
|
regulation of myeloid leukocyte mediated immunity
|
GO:0002886 |
25 |
0.064
|
|
|
|
membrane invagination
|
GO:0010324 |
17 |
0.064
|
|
|
|
positive regulation of phospholipase c activity
|
GO:0010863 |
2 |
0.063
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.063
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.063
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
44 |
0.062
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.062
|
|
|
|
negative regulation of toll like receptor signaling pathway
|
GO:0034122 |
14 |
0.062
|
|
|
|
regulation of hypersensitivity
|
GO:0002883 |
10 |
0.062
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.062
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.062
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.062
|
Mouse |
|
|
detection of stimulus
|
GO:0051606 |
84 |
0.060
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.060
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.060
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.060
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.059
|
|
|
|
dendritic cell antigen processing and presentation
|
GO:0002468 |
7 |
0.059
|
|
|
|
microglia differentiation
|
GO:0014004 |
2 |
0.059
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.059
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.059
|
|
|
|
mast cell mediated immunity
|
GO:0002448 |
20 |
0.059
|
|
|
|
negative regulation of b cell proliferation
|
GO:0030889 |
13 |
0.058
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.058
|
Mouse |
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.057
|
|
|
|
myelination
|
GO:0042552 |
74 |
0.057
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.057
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.056
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.056
|
Mouse |
|
|
developmental maturation
|
GO:0021700 |
193 |
0.056
|
|
|
|
mast cell proliferation
|
GO:0070662 |
4 |
0.055
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.055
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.055
|
Mouse |
|
|
fc receptor mediated inhibitory signaling pathway
|
GO:0002774 |
1 |
0.055
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.054
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.054
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.053
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.053
|
Mouse |
|
|
cellular extravasation
|
GO:0045123 |
17 |
0.052
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.052
|
Mouse |
|
|
negative regulation of phagocytosis
|
GO:0050765 |
4 |
0.052
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.052
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.052
|
|
|
|
tumor necrosis factor biosynthetic process
|
GO:0042533 |
10 |
0.052
|
Mouse |
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.051
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.051
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.051
|
|
|
|
negative regulation of type 2 immune response
|
GO:0002829 |
8 |
0.051
|
|
|
|
cellular response to interleukin 15
|
GO:0071350 |
2 |
0.050
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
26 |
0.050
|
|
|
|
detection of yeast
|
GO:0001879 |
2 |
0.049
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.049
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.049
|
|
|
|
regulation of acute inflammatory response
|
GO:0002673 |
27 |
0.049
|
|
|
|
negative regulation of type i hypersensitivity
|
GO:0001811 |
1 |
0.049
|
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
25 |
0.048
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.048
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.048
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.048
|
|
|
|
activation of mapk activity involved in innate immune response
|
GO:0035419 |
2 |
0.048
|
|
|
|
antigen processing and presentation of exogenous antigen
|
GO:0019884 |
26 |
0.048
|
|
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.048
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.047
|
Mouse |
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.047
|
|
|
|
positive regulation of humoral immune response
|
GO:0002922 |
11 |
0.047
|
|
|
|
tolerance induction to self antigen
|
GO:0002513 |
4 |
0.047
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.047
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
54 |
0.046
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.046
|
|
|
|
interleukin 12 production
|
GO:0032615 |
32 |
0.046
|
Mouse |
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
41 |
0.046
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.046
|
|
|
|
protein digestion
|
GO:0044256 |
1 |
0.046
|
|
|
|
t cell migration
|
GO:0072678 |
19 |
0.046
|
|
|
|
mast cell activation
|
GO:0045576 |
27 |
0.046
|
|
|
|
regulation of regulated secretory pathway
|
GO:1903305 |
20 |
0.045
|
|
|
|
positive regulation of interferon alpha biosynthetic process
|
GO:0045356 |
1 |
0.045
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.045
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.045
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.045
|
|
|
|
positive regulation of antigen receptor mediated signaling pathway
|
GO:0050857 |
9 |
0.045
|
|
|
|
regulation of neutrophil migration
|
GO:1902622 |
14 |
0.045
|
|
|
|
eosinophil migration
|
GO:0072677 |
3 |
0.045
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.045
|
Mouse |
|
|
b cell homeostasis
|
GO:0001782 |
34 |
0.044
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.044
|
|
|
|
regulation of natural killer cell mediated cytotoxicity
|
GO:0042269 |
19 |
0.044
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.044
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.044
|
Mouse |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.043
|
|
|
|
regulation of glial cell differentiation
|
GO:0045685 |
41 |
0.043
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.043
|
|
|
|
cellular response to prostaglandin d stimulus
|
GO:0071799 |
1 |
0.043
|
|
|
|
positive regulation of granulocyte macrophage colony stimulating factor biosynthetic process
|
GO:0045425 |
2 |
0.043
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.043
|
|
|
|
negative regulation of angiogenesis
|
GO:0016525 |
25 |
0.043
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.043
|
Mouse |
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.042
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.042
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.042
|
|
|
|
immune response inhibiting cell surface receptor signaling pathway
|
GO:0002767 |
3 |
0.042
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.042
|
Mouse |
|
|
negative regulation of macrophage apoptotic process
|
GO:2000110 |
3 |
0.042
|
|
|
|
positive regulation of granulocyte chemotaxis
|
GO:0071624 |
12 |
0.041
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.041
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.041
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.041
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.041
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.041
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.041
|
|
|
|
platelet activation
|
GO:0030168 |
40 |
0.041
|
Mouse |
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.041
|
|
|
|
regulation of bone resorption
|
GO:0045124 |
24 |
0.041
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
40 |
0.041
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.040
|
Mouse |
|
|
sensory perception
|
GO:0007600 |
245 |
0.040
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.040
|
|
|
|
regulation of leukocyte mediated cytotoxicity
|
GO:0001910 |
38 |
0.040
|
|
|
|
complement receptor mediated signaling pathway
|
GO:0002430 |
1 |
0.040
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.040
|
Mouse |
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
36 |
0.040
|
|
|
|
circadian temperature homeostasis
|
GO:0060086 |
2 |
0.040
|
|
|
|
hypersensitivity
|
GO:0002524 |
10 |
0.040
|
|
|
|
lamellipodium organization
|
GO:0097581 |
29 |
0.040
|
|
|
|
regulation of interleukin 1 beta secretion
|
GO:0050706 |
15 |
0.040
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
107 |
0.039
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.039
|
Mouse |
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.039
|
Mouse |
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.038
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
54 |
0.038
|
|
|
|
negative regulation of leukocyte degranulation
|
GO:0043301 |
7 |
0.038
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.038
|
|
|
|
negative regulation of vasculature development
|
GO:1901343 |
26 |
0.038
|
|
|
|
branching involved in mammary gland duct morphogenesis
|
GO:0060444 |
27 |
0.037
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.037
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.037
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.036
|
|
|
|
negative regulation of innate immune response
|
GO:0045824 |
17 |
0.036
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.036
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.036
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.036
|
Mouse |
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.035
|
|
|
|
positive regulation of mast cell degranulation
|
GO:0043306 |
10 |
0.035
|
|
|
|
sensitization
|
GO:0046960 |
2 |
0.035
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.035
|
|
|
|
negative regulation of hypersensitivity
|
GO:0002884 |
3 |
0.035
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.035
|
|
|
|
defense response to protozoan
|
GO:0042832 |
25 |
0.035
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.035
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.035
|
|
|
|
platelet derived growth factor receptor signaling pathway
|
GO:0048008 |
32 |
0.034
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.034
|
|
|
|
negative regulation of regulatory t cell differentiation
|
GO:0045590 |
2 |
0.034
|
|
|
|
positive regulation of neutrophil migration
|
GO:1902624 |
12 |
0.034
|
|
|
|
positive regulation of acute inflammatory response
|
GO:0002675 |
16 |
0.034
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
20 |
0.034
|
|
|
|
regulation of glycoprotein biosynthetic process
|
GO:0010559 |
12 |
0.034
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.033
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.033
|
Mouse |
|
|
hemostasis
|
GO:0007599 |
78 |
0.033
|
Mouse |
|
|
regulation of lymphocyte migration
|
GO:2000401 |
14 |
0.033
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.033
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.033
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.033
|
|
|
|
melanocyte migration
|
GO:0097324 |
2 |
0.033
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.033
|
Mouse |
|
|
regulation of interferon alpha production
|
GO:0032647 |
5 |
0.032
|
Mouse |
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.032
|
|
|
|
filtration diaphragm assembly
|
GO:0036058 |
1 |
0.032
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.032
|
|
