IMP
Process View
negative regulation of leukocyte degranulation
Any process that stops, prevents, or reduces the rate of leukocyte degranulation.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of leukocyte degranulation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Ccr2 | chemokine (C-C motif) receptor 2 | 0.226 | ||
| Ccr5 | chemokine (C-C motif) receptor 5 | 0.224 | Mouse | |
| Fgr | Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog | 0.175 | ||
| Ccl3 | chemokine (C-C motif) ligand 3 | 0.162 | ||
| Ccl2 | chemokine (C-C motif) ligand 2 | 0.158 | ||
| Mefv | Mediterranean fever | 0.102 | ||
| Selp | selectin, platelet | 0.080 | ||
| Fcrla | Fc receptor-like A | 0.058 | ||
| Cxcl13 | chemokine (C-X-C motif) ligand 13 | 0.044 | ||
| Cxcr2 | chemokine (C-X-C motif) receptor 2 | 0.044 | Mouse | |
| Blk | B lymphoid kinase | 0.043 | ||
| Klrb1b | killer cell lectin-like receptor subfamily B member 1B | 0.040 | ||
| Ifng | interferon gamma | 0.039 | ||
| Csf3r | colony stimulating factor 3 receptor (granulocyte) | 0.038 | ||
| Cd180 | CD180 antigen | 0.038 | ||
| Lgr4 | leucine-rich repeat-containing G protein-coupled receptor 4 | 0.037 | ||
| Cxcr3 | chemokine (C-X-C motif) receptor 3 | 0.035 | Mouse | |
| Clec4a2 | C-type lectin domain family 4, member a2 | 0.034 | ||
| Trem3 | triggering receptor expressed on myeloid cells 3 | 0.034 | ||
| Itgax | integrin alpha X | 0.033 | ||
| Tgfb2 | transforming growth factor, beta 2 | 0.031 | ||
| Ccr1 | chemokine (C-C motif) receptor 1 | 0.031 | Mouse | |
| Tnfsf14 | tumor necrosis factor (ligand) superfamily, member 14 | 0.030 | ||
| Cd22 | CD22 antigen | 0.029 | ||
| Mb | myoglobin | 0.025 | ||
| Slpi | secretory leukocyte peptidase inhibitor | 0.025 | ||
| Prdm1 | PR domain containing 1, with ZNF domain | 0.024 | ||
| Cd44 | CD44 antigen | 0.023 | ||
| Il1r1 | interleukin 1 receptor, type I | 0.023 | ||
| Il1b | interleukin 1 beta | 0.023 | ||
| Cd33 | CD33 antigen | 0.022 | ||
| Klrk1 | killer cell lectin-like receptor subfamily K, member 1 | 0.022 | ||
| Tlr2 | toll-like receptor 2 | 0.021 | ||
| Slfn4 | schlafen 4 | 0.021 | ||
| Tnf | tumor necrosis factor | 0.020 | ||
| Il18rap | interleukin 18 receptor accessory protein | 0.019 | ||
| Fcgr1 | Fc receptor, IgG, high affinity I | 0.019 | ||
| Ccl4 | chemokine (C-C motif) ligand 4 | 0.018 | ||
| Tlr8 | toll-like receptor 8 | 0.018 | ||
| Tlr4 | toll-like receptor 4 | 0.018 | ||
| Klra2 | killer cell lectin-like receptor, subfamily A, member 2 | 0.018 | ||
| Il1f9 | interleukin 1 family, member 9 | 0.018 | ||
| Icos | inducible T-cell co-stimulator | 0.018 | ||
| Il10ra | interleukin 10 receptor, alpha | 0.018 | ||
| Cd40 | CD40 antigen | 0.017 | ||
| Ccr6 | chemokine (C-C motif) receptor 6 | 0.017 | Mouse | |
| Klrg1 | killer cell lectin-like receptor subfamily G, member 1 | 0.017 | ||
| Il4 | interleukin 4 | 0.016 | ||
| Ciita | class II transactivator | 0.016 | ||
| Ctla4 | cytotoxic T-lymphocyte-associated protein 4 | 0.016 | ||
| Clec4d | C-type lectin domain family 4, member d | 0.015 | ||
| Cd7 | CD7 antigen | 0.015 | ||
| Ncr1 | natural cytotoxicity triggering receptor 1 | 0.014 | ||
| Tlr7 | toll-like receptor 7 | 0.014 | ||
| Nkx2-3 | NK2 transcription factor related, locus 3 (Drosophila) | 0.014 | ||
| Fcer2a | Fc receptor, IgE, low affinity II, alpha polypeptide | 0.014 | ||
| Trem1 | triggering receptor expressed on myeloid cells 1 | 0.014 | ||
| Klrd1 | killer cell lectin-like receptor, subfamily D, member 1 | 0.014 | ||
| Snai1 | snail homolog 1 (Drosophila) | 0.014 | ||
| Pilrb1 | paired immunoglobin-like type 2 receptor beta 1 | 0.014 | ||
| Fcgr4 | Fc receptor, IgG, low affinity IV | 0.014 | ||
| Clec5a | C-type lectin domain family 5, member a | 0.013 | ||
| Pilra | paired immunoglobin-like type 2 receptor alpha | 0.013 | ||
| Pik3cg | phosphoinositide-3-kinase, catalytic, gamma polypeptide | 0.013 | ||
| Fpr1 | formyl peptide receptor 1 | 0.013 | ||
| Map3k14 | mitogen-activated protein kinase kinase kinase 14 | 0.013 | ||
| H2-Ob | histocompatibility 2, O region beta locus | 0.012 | ||
| Trpv1 | transient receptor potential cation channel, subfamily V, member 1 | 0.012 | ||
| Fasl | Fas ligand (TNF superfamily, member 6) | 0.012 | ||
| Lair1 | leukocyte-associated Ig-like receptor 1 | 0.012 | ||
| Ear2 | eosinophil-associated, ribonuclease A family, member 2 | 0.012 | ||
| Irg1 | immunoresponsive gene 1 | 0.012 | ||
| Nos2 | nitric oxide synthase 2, inducible | 0.012 | ||
| Ccr9 | chemokine (C-C motif) receptor 9 | 0.012 | Mouse | |
| Dock1 | dedicator of cytokinesis 1 | 0.012 | ||
| Efna1 | ephrin A1 | 0.012 | ||
| Emr4 | EGF-like module containing, mucin-like, hormone receptor-like sequence 4 | 0.012 | ||
| Cd3e | CD3 antigen, epsilon polypeptide | 0.011 | ||
| Cd300lb | CD300 antigen like family member B | 0.011 | Mouse | |
| C5ar1 | complement component 5a receptor 1 | 0.011 | ||
| Mmp8 | matrix metallopeptidase 8 | 0.011 | ||
| Siglece | sialic acid binding Ig-like lectin E | 0.011 | ||
| Gzmb | granzyme B | 0.011 | ||
| Slamf6 | SLAM family member 6 | 0.010 | ||
| Cd4 | CD4 antigen | 0.010 | ||
| Csf2rb | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.010 | ||
| Abcg3 | ATP-binding cassette, sub-family G (WHITE), member 3 | 0.010 | ||
| Mmp9 | matrix metallopeptidase 9 | 0.010 |