|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
1.000
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
1.000
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
1.000
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
1.000
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
1.000
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
1.000
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.999
|
|
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.999
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
20 |
0.998
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.998
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.998
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.998
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.997
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.997
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.997
|
|
|
|
cd4 positive or cd8 positive alpha beta t cell lineage commitment
|
GO:0043369 |
8 |
0.996
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.996
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.996
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.995
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.995
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.994
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.993
|
|
|
|
humoral immune response mediated by circulating immunoglobulin
|
GO:0002455 |
14 |
0.991
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.990
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.988
|
|
|
|
negative regulation of b cell activation
|
GO:0050869 |
27 |
0.987
|
|
|
|
positive regulation of gamma delta t cell differentiation
|
GO:0045588 |
6 |
0.987
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
28 |
0.986
|
|
|
|
regulation of b cell differentiation
|
GO:0045577 |
23 |
0.984
|
|
|
|
positive regulation of isotype switching to igg isotypes
|
GO:0048304 |
7 |
0.983
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.983
|
|
|
|
regulation of tumor necrosis factor biosynthetic process
|
GO:0042534 |
10 |
0.983
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.982
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.982
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.981
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.981
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.981
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.978
|
|
|
|
negative regulation of b cell proliferation
|
GO:0030889 |
13 |
0.977
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.977
|
|
|
|
regulation of toll like receptor 4 signaling pathway
|
GO:0034143 |
4 |
0.976
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.974
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.974
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.974
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.973
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.973
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.970
|
|
|
|
thymic t cell selection
|
GO:0045061 |
22 |
0.967
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.967
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.963
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.963
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.962
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.961
|
|
|
|
regulation of toll like receptor 2 signaling pathway
|
GO:0034135 |
3 |
0.961
|
|
|
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.961
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.957
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.955
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.953
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.952
|
|
|
|
negative thymic t cell selection
|
GO:0045060 |
12 |
0.952
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.948
|
|
|
|
immunoglobulin secretion
|
GO:0048305 |
17 |
0.947
|
|
|
|
t cell selection
|
GO:0045058 |
34 |
0.947
|
|
|
|
v d j recombination
|
GO:0033151 |
14 |
0.946
|
|
|
|
lymph node development
|
GO:0048535 |
18 |
0.946
|
|
|
|
necroptotic signaling pathway
|
GO:0097527 |
3 |
0.946
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.945
|
|
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.942
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.935
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.933
|
|
|
|
somatic cell dna recombination
|
GO:0016444 |
51 |
0.933
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.933
|
|
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
16 |
0.928
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.927
|
|
|
|
regulation of corticotropin releasing hormone secretion
|
GO:0043397 |
2 |
0.927
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.926
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.919
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.918
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.917
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.917
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.912
|
|
|
|
positive regulation of inflammatory response to antigenic stimulus
|
GO:0002863 |
11 |
0.911
|
|
|
|
regulation of regulated secretory pathway
|
GO:1903305 |
20 |
0.911
|
|
|
|
regulation of t cell anergy
|
GO:0002667 |
4 |
0.910
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.909
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.907
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.907
|
|
|
|
positive regulation of b cell mediated immunity
|
GO:0002714 |
26 |
0.907
|
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
0.907
|
|
|
|
regulation of type iia hypersensitivity
|
GO:0001796 |
4 |
0.907
|
|
|
|
negative regulation of b cell mediated immunity
|
GO:0002713 |
7 |
0.900
|
|
|
|
modification by symbiont of host morphology or physiology
|
GO:0044003 |
4 |
0.899
|
|
|
|
tumor necrosis factor mediated signaling pathway
|
GO:0033209 |
13 |
0.897
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.897
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.894
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.889
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.885
|
|
|
|
positive regulation of b cell proliferation
|
GO:0030890 |
24 |
0.884
|
|
|
|
regulation of monocyte extravasation
|
GO:2000437 |
2 |
0.882
|
|
|
|
negative regulation of interleukin 2 biosynthetic process
|
GO:0045085 |
3 |
0.873
|
|
|
|
regulation of isotype switching
|
GO:0045191 |
22 |
0.872
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.869
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.869
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.869
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.862
|
|
|
|
positive regulation of type ii hypersensitivity
|
GO:0002894 |
4 |
0.860
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.858
|
|
|
|
myd88 independent toll like receptor signaling pathway
|
GO:0002756 |
3 |
0.855
|
|
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.853
|
|
|
|
negative regulation of inflammatory response to antigenic stimulus
|
GO:0002862 |
10 |
0.852
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.852
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.851
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.839
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.837
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.836
|
|
|
|
inflammatory response to antigenic stimulus
|
GO:0002437 |
30 |
0.836
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.829
|
|
|
|
detection of mechanical stimulus involved in sensory perception of pain
|
GO:0050966 |
4 |
0.828
|
|
|
|
acute inflammatory response to antigenic stimulus
|
GO:0002438 |
12 |
0.828
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.827
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.826
|
|
|
|
positive regulation of antigen receptor mediated signaling pathway
|
GO:0050857 |
9 |
0.817
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.807
|
|
|
|
positive regulation of leukocyte apoptotic process
|
GO:2000108 |
21 |
0.799
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.798
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.791
|
|
|
|
mast cell mediated immunity
|
GO:0002448 |
20 |
0.790
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.785
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.785
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.780
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.777
|
|
|
|
dendritic cell apoptotic process
|
GO:0097048 |
3 |
0.774
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.770
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.768
|
|
|
|
positive regulation of podosome assembly
|
GO:0071803 |
3 |
0.764
|
|
|
|
positive regulation of b cell receptor signaling pathway
|
GO:0050861 |
4 |
0.764
|
|
|
|
modulation by virus of host process
|
GO:0019054 |
2 |
0.763
|
|
|
|
positive regulation of translational initiation
|
GO:0045948 |
4 |
0.762
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.762
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.753
|
|
|
|
positive regulation of interleukin 2 production
|
GO:0032743 |
19 |
0.739
|
|
|
|
thymus development
|
GO:0048538 |
41 |
0.732
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
23 |
0.731
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.729
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.725
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
36 |
0.724
|
|
|
|
t cell homeostasis
|
GO:0043029 |
35 |
0.723
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
34 |
0.718
|
|
|
|
b cell lineage commitment
|
GO:0002326 |
4 |
0.712
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.711
|
|
|
|
positive regulation of chronic inflammatory response
|
GO:0002678 |
4 |
0.709
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.708
|
|
|
|
tumor necrosis factor biosynthetic process
|
GO:0042533 |
10 |
0.707
|
|
|
|
negative regulation of regulatory t cell differentiation
|
GO:0045590 |
2 |
0.706
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.705
|
|
|
|
histamine production involved in inflammatory response
|
GO:0002349 |
1 |
0.705
|
|
|
|
dendritic cell differentiation
|
GO:0097028 |
26 |
0.705
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.696
|
|
|
|
bone remodeling
|
GO:0046849 |
53 |
0.693
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.691
|
|
|
|
programmed necrotic cell death
|
GO:0097300 |
28 |
0.687
|
|
|
|
positive regulation of antibacterial peptide biosynthetic process
|
GO:0006963 |
1 |
0.680
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.680
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.680
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.677
|
|
|
|
positive regulation of translational initiation by iron
|
GO:0045994 |
2 |
0.670
|
|
|
|
interleukin 4 production
|
GO:0032633 |
24 |
0.669
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.668
|
|
|
|
b cell apoptotic process
|
GO:0001783 |
19 |
0.667
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.665
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.662
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.658
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.656
|
|
|
|
negative regulation of toll like receptor 2 signaling pathway
|
GO:0034136 |
3 |
0.654
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.654
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.650
|
|
|
|
negative t cell selection
|
GO:0043383 |
13 |
0.648
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.644
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.640
|
|
|
|
positive regulation of chronic inflammatory response to antigenic stimulus
|
GO:0002876 |
2 |
0.637
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.635
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.634
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.632
|
|
|
|
isotype switching to igg isotypes
|
GO:0048291 |
10 |
0.623
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.621
|
|
|
|
b cell homeostasis
|
GO:0001782 |
34 |
0.621
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.619
|
|
|
|
regulation of hypersensitivity
|
GO:0002883 |
10 |
0.614
|
|
|
|
regulation of dendritic cell apoptotic process
|
GO:2000668 |
3 |
0.611
|
|
|
|
platelet aggregation
|
GO:0070527 |
20 |
0.603
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.597
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.596
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.593
|
|
|
|
regulation of mast cell degranulation
|
GO:0043304 |
16 |
0.591
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.590
|
|
|
|
regulation of tolerance induction dependent upon immune response
|
GO:0002652 |
1 |
0.587
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
30 |
0.584
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.581
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.580
|
|
|
|
interleukin 10 secretion
|
GO:0072608 |
4 |
0.580
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.579
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.577
|
|
|
|
regulation of interleukin 6 biosynthetic process
|
GO:0045408 |
11 |
0.576
|
|
|
|
regulation of cytokine secretion involved in immune response
|
GO:0002739 |
4 |
0.575
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.575
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.569
|
|
|
|
negative regulation of growth of symbiont in host
|
GO:0044130 |
19 |
0.567
|
|
|
|
regulation of humoral immune response
|
GO:0002920 |
22 |
0.564
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.563
|
|
|
|
growth involved in symbiotic interaction
|
GO:0044110 |
23 |
0.562
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.560
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.558
|
|
|
|
fc receptor mediated inhibitory signaling pathway
|
GO:0002774 |
1 |
0.556
|
|
|
|
activation induced cell death of t cells
|
GO:0006924 |
10 |
0.551
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.551
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
34 |
0.550
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.550
|
|
|
|
necrotic cell death
|
GO:0070265 |
30 |
0.547
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.538
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.536
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.534
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.528
|
|
|
|
positive regulation of regulatory t cell differentiation
|
GO:0045591 |
4 |
0.524
|
|
|
|
platelet degranulation
|
GO:0002576 |
6 |
0.517
|
|
|
|
organ regeneration
|
GO:0031100 |
2 |
0.516
|
|
|
|
regulated secretory pathway
|
GO:0045055 |
32 |
0.511
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.510
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.509
|
|
|
|
positive regulation of interferon alpha production
|
GO:0032727 |
4 |
0.509
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.506
|
|
|
|
antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii
|
GO:0002504 |
17 |
0.505
|
|
|
|
granulocyte activation
|
GO:0036230 |
10 |
0.504
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.503
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.502
|
|
|
|
response to platelet derived growth factor
|
GO:0036119 |
6 |
0.499
|
|
|
|
regulation of eosinophil degranulation
|
GO:0043309 |
1 |
0.490
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.488
|
|
|
|
positive regulation of isotype switching
|
GO:0045830 |
15 |
0.484
|
|
|
|
granulocyte macrophage colony stimulating factor production
|
GO:0032604 |
3 |
0.478
|
|
|
|
neutrophil differentiation
|
GO:0030223 |
3 |
0.475
|
|
|
|
regulation of fever generation by regulation of prostaglandin secretion
|
GO:0071810 |
2 |
0.474
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.473
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.472
|
|
|
|
lymphocyte anergy
|
GO:0002249 |
4 |
0.471
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.471
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
20 |
0.469
|
|
|
|
regulation of neutrophil differentiation
|
GO:0045658 |
2 |
0.469
|
|
|
|
regulation of b cell apoptotic process
|
GO:0002902 |
13 |
0.469
|
|
|
|
inflammatory cell apoptotic process
|
GO:0006925 |
11 |
0.463
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.463
|
|
|
|
regulation of phosphatidylinositol 3 kinase activity
|
GO:0043551 |
14 |
0.459
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.458
|
|
|
|
positive regulation of protein homooligomerization
|
GO:0032464 |
3 |
0.458
|
|
|
|
regulation of homotypic cell cell adhesion
|
GO:0034110 |
13 |
0.458
|
|
|
|
positive regulation of granulocyte macrophage colony stimulating factor biosynthetic process
|
GO:0045425 |
2 |
0.457
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.457
|
|
|
|
exocrine system development
|
GO:0035272 |
45 |
0.455
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.455
|
|
|
|
interleukin 5 secretion
|
GO:0072603 |
2 |
0.453
|
|
|
|
regulation of isotype switching to igg isotypes
|
GO:0048302 |
10 |
0.452
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.451
|
|
|
|
osteoclast development
|
GO:0036035 |
9 |
0.451
|
|
|
|
nucleotide binding oligomerization domain containing 2 signaling pathway
|
GO:0070431 |
6 |
0.444
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.443
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.443
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase activity
|
GO:0043552 |
11 |
0.435
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.427
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.426
|
|
|
|
immune response inhibiting signal transduction
|
GO:0002765 |
4 |
0.426
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.421
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.420
|
|
|
|
regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043370 |
21 |
0.420
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.414
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.411
|
|
|
|
positive regulation of humoral immune response
|
GO:0002922 |
11 |
0.408
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.405
|
|
|
|
fatty acid biosynthetic process
|
GO:0006633 |
41 |
0.404
|
|
|
|
myeloid dendritic cell activation
|
GO:0001773 |
25 |
0.398
|
|
|
|
t cell receptor v d j recombination
|
GO:0033153 |
5 |
0.396
|
|
|
|
regulation of acute inflammatory response
|
GO:0002673 |
27 |
0.396
|
|
|
|
t helper 2 cell differentiation
|
GO:0045064 |
12 |
0.395
|
|
|
|
bone resorption
|
GO:0045453 |
38 |
0.395
|
|
|
|
positive regulation of myeloid leukocyte mediated immunity
|
GO:0002888 |
14 |
0.394
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.392
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.392
|
|
|
|
positive regulation of t cell receptor signaling pathway
|
GO:0050862 |
4 |
0.388
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.385
|
|
|
|
positive regulation of acute inflammatory response
|
GO:0002675 |
16 |
0.382
|
|
|
|
growth of symbiont in host
|
GO:0044117 |
23 |
0.377
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.374
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.373
|
|
|
|
regulation of interleukin 13 secretion
|
GO:2000665 |
2 |
0.373
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
23 |
0.372
|
|
|
|
chronic inflammatory response
|
GO:0002544 |
9 |
0.370
|
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
25 |
0.370
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.369
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.369
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.366
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.364
|
|
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
22 |
0.364
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.363
|
|
|
|
glial cell apoptotic process
|
GO:0034349 |
3 |
0.362
|
|
|
|
apoptotic process involved in mammary gland involution
|
GO:0060057 |
4 |
0.360
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.359
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.358
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
43 |
0.358
|
|
|
|
immune response inhibiting cell surface receptor signaling pathway
|
GO:0002767 |
3 |
0.358
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.357
|
|
|
|
positive regulation of mast cell activation involved in immune response
|
GO:0033008 |
10 |
0.356
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.356
|
|
|
|
regulation of type i hypersensitivity
|
GO:0001810 |
4 |
0.355
|
|
|
|
toll like receptor 4 signaling pathway
|
GO:0034142 |
9 |
0.354
|
|
|
|
negative regulation of hypersensitivity
|
GO:0002884 |
3 |
0.351
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
42 |
0.348
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
30 |
0.347
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.343
|
|
|
|
regulation of toll like receptor signaling pathway
|
GO:0034121 |
20 |
0.343
|
|
|
|
positive regulation of immature t cell proliferation
|
GO:0033091 |
4 |
0.341
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.339
|
|
|
|
cd4 positive cd25 positive alpha beta regulatory t cell differentiation
|
GO:0002361 |
4 |
0.335
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.333
|
|
|
|
negative regulation of chronic inflammatory response
|
GO:0002677 |
3 |
0.333
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
42 |
0.331
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.330
|
|
|
|
activation of phospholipase c activity
|
GO:0007202 |
2 |
0.330
|
|
|
|
homotypic cell cell adhesion
|
GO:0034109 |
28 |
0.329
|
|
|
|
cellular response to amino acid stimulus
|
GO:0071230 |
29 |
0.327
|
|
|
|
necroptotic process
|
GO:0070266 |
21 |
0.326
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.326
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.326
|
|
|
|
protein activation cascade
|
GO:0072376 |
19 |
0.325
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.325
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.324
|
|
|
|
positive regulation of acute inflammatory response to antigenic stimulus
|
GO:0002866 |
7 |
0.319
|
|
|
|
gamma delta t cell differentiation
|
GO:0042492 |
11 |
0.318
|
|
|
|
regulation of podosome assembly
|
GO:0071801 |
3 |
0.314
|
|
|
|
regulation of gamma delta t cell differentiation
|
GO:0045586 |
9 |
0.312
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.312
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.311
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.310
|
|
|
|
regulation of interleukin 10 biosynthetic process
|
GO:0045074 |
1 |
0.310
|
|
|
|
positive regulation of phospholipase c activity
|
GO:0010863 |
2 |
0.308
|
|
|
|
positive regulation of immunoglobulin mediated immune response
|
GO:0002891 |
26 |
0.308
|
|
|
|
positive regulation of type iii hypersensitivity
|
GO:0001805 |
3 |
0.306
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.300
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.298
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.294
|
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.292
|
|
|
|
tolerance induction
|
GO:0002507 |
14 |
0.292
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.288
|
|
|
|
positive regulation of hypersensitivity
|
GO:0002885 |
7 |
0.288
|
|
|
|
pre b cell differentiation
|
GO:0002329 |
7 |
0.287
|
|
|
|
modulation by symbiont of host cellular process
|
GO:0044068 |
2 |
0.284
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.284
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
26 |
0.281
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.280
|
|
|
|
regulation of humoral immune response mediated by circulating immunoglobulin
|
GO:0002923 |
10 |
0.279
|
|
|
|
positive regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042523 |
6 |
0.277
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
28 |
0.276
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.275
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.274
|
|
|
|
positive regulation of leukocyte degranulation
|
GO:0043302 |
10 |
0.272
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.270
|
|
|
|
t cell apoptotic process
|
GO:0070231 |
39 |
0.269
|
|
|
|
negative regulation of interleukin 5 production
|
GO:0032714 |
4 |
0.269
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
41 |
0.267
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.265
|
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
27 |
0.265
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.264
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.263
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.261
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.259
|
|
|
|
t cell homeostatic proliferation
|
GO:0001777 |
4 |
0.257
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.253
|
|
|
|
nerve development
|
GO:0021675 |
67 |
0.252
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.252
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.251
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.243
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.243
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.243
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.241
|
|
|
|
hematopoietic stem cell migration
|
GO:0035701 |
1 |
0.238
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.235
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
45 |
0.231
|
|
|
|
eosinophil activation
|
GO:0043307 |
1 |
0.230
|
|
|
|
positive regulation of cd4 positive cd25 positive alpha beta regulatory t cell differentiation
|
GO:0032831 |
2 |
0.229
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.229
|
|
|
|
t helper 17 cell differentiation
|
GO:0072539 |
7 |
0.229
|
|
|
|
immune complex clearance
|
GO:0002434 |
2 |
0.229
|
|
|
|
regulation of growth of symbiont in host
|
GO:0044126 |
19 |
0.228
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.228
|
|
|
|
negative regulation of humoral immune response mediated by circulating immunoglobulin
|
GO:0002924 |
3 |
0.224
|
|
|
|
antibody dependent cellular cytotoxicity
|
GO:0001788 |
2 |
0.224
|
|
|
|
positive regulation of cd24 biosynthetic process
|
GO:2000560 |
1 |
0.223
|
|
|
|
positive regulation of tyrosine phosphorylation of stat protein
|
GO:0042531 |
15 |
0.222
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.222
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.221
|
|
|
|
glycogen cell differentiation involved in embryonic placenta development
|
GO:0060709 |
1 |
0.219
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.219
|
|
|
|
immature b cell differentiation
|
GO:0002327 |
10 |
0.219
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.219
|
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
31 |
0.217
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.216
|
|
|
|
t helper cell lineage commitment
|
GO:0002295 |
6 |
0.213
|
|
|
|
regulation of t helper 2 cell differentiation
|
GO:0045628 |
8 |
0.213
|
|
|
|
response to amino acid
|
GO:0043200 |
37 |
0.212
|
|
|
|
regulation of platelet activation
|
GO:0010543 |
17 |
0.212
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.210
|
|
|
|
positive regulation of lipid transport
|
GO:0032370 |
22 |
0.209
|
|
|
|
mast cell proliferation
|
GO:0070662 |
4 |
0.208
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
52 |
0.208
|
|
|
|
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002823 |
23 |
0.208
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.207
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.207
|
|
|
|
response to water
|
GO:0009415 |
1 |
0.205
|
|
|
|
corticotropin releasing hormone secretion
|
GO:0043396 |
2 |
0.204
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.202
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.202
|
|
|
|
detection of mechanical stimulus involved in sensory perception
|
GO:0050974 |
23 |
0.199
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.198
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.196
|
|
|
|
response to retinoic acid
|
GO:0032526 |
56 |
0.195
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.195
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.194
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.192
|
|
|
|
negative regulation of toll like receptor signaling pathway
|
GO:0034122 |
14 |
0.191
|
|
|
|
regulation of gamma delta t cell activation
|
GO:0046643 |
9 |
0.191
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.190
|
|
|
|
positive regulation of b cell differentiation
|
GO:0045579 |
13 |
0.190
|
|
|
|
mast cell degranulation
|
GO:0043303 |
19 |
0.189
|
|
|
|
positive regulation of oligodendrocyte differentiation
|
GO:0048714 |
9 |
0.189
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
33 |
0.188
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.188
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.187
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.186
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.186
|
|
|
|
response to metal ion
|
GO:0010038 |
47 |
0.184
|
|
|
|
regulation of granulocyte macrophage colony stimulating factor biosynthetic process
|
GO:0045423 |
2 |
0.183
|
|
|
|
negative regulation of fibroblast proliferation
|
GO:0048147 |
14 |
0.182
|
|
|
|
positive regulation of alpha beta t cell proliferation
|
GO:0046641 |
12 |
0.182
|
|
|
|
helper t cell chemotaxis
|
GO:0035704 |
1 |
0.182
|
|
|
|
regulation of granulocyte macrophage colony stimulating factor production
|
GO:0032645 |
3 |
0.182
|
|
|
|
actin cytoskeleton reorganization
|
GO:0031532 |
21 |
0.181
|
|
|
|
interleukin 3 biosynthetic process
|
GO:0042223 |
2 |
0.177
|
|
|
|
regulation of dendritic cell chemotaxis
|
GO:2000508 |
1 |
0.176
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.175
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.173
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.173
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.167
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.165
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.164
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.163
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.161
|
|
|
|
endoderm formation
|
GO:0001706 |
20 |
0.160
|
|
|
|
regulation of myd88 independent toll like receptor signaling pathway
|
GO:0034127 |
1 |
0.159
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.158
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.157
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.157
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.156
|
|
|
|
histamine secretion by mast cell
|
GO:0002553 |
1 |
0.155
|
|
|
|
filtration diaphragm assembly
|
GO:0036058 |
1 |
0.155
|
|
|
|
platelet activation
|
GO:0030168 |
40 |
0.153
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.153
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.153
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.153
|
|
|
|
regulation of protein oligomerization
|
GO:0032459 |
4 |
0.152
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
36 |
0.151
|
|
|
|
negative regulation of myeloid leukocyte differentiation
|
GO:0002762 |
20 |
0.151
|
|
|
|
alpha beta t cell lineage commitment
|
GO:0002363 |
7 |
0.151
|
|
|
|
interleukin 10 biosynthetic process
|
GO:0042091 |
1 |
0.150
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.149
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.148
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
82 |
0.148
|
|
|
|
positive regulation of lymphocyte anergy
|
GO:0002913 |
4 |
0.147
|
|
|
|
negative regulation of vasculature development
|
GO:1901343 |
26 |
0.146
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.146
|
|
|
|
regulation of interleukin 10 production
|
GO:0032653 |
21 |
0.146
|
|
|
|
monocyte extravasation
|
GO:0035696 |
2 |
0.144
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.144
|
|
|
|
negative regulation of t helper 2 cell differentiation
|
GO:0045629 |
4 |
0.143
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.143
|
|
|
|
regulation of oligodendrocyte differentiation
|
GO:0048713 |
23 |
0.143
|
|
|
|
positive regulation of dendritic cell apoptotic process
|
GO:2000670 |
3 |
0.142
|
|
|
|
translational initiation
|
GO:0006413 |
24 |
0.140
|
|
|
|
negative regulation of mast cell proliferation
|
GO:0070667 |
1 |
0.140
|
|
|
|
positive regulation of fever generation
|
GO:0031622 |
6 |
0.140
|
|
