Mus musculus

74 known processes

Ciita

class II transactivator

(Aliases: EG669998,C2ta,Gm9475,MGC130299)

Ciita biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
innate immune response GO:0045087 157 0.862
t cell selection GO:0045058 34 0.854
positive regulation of cell activation GO:0050867 158 0.805
antigen processing and presentation GO:0019882 47 0.786
Mouse
adaptive immune response GO:0002250 155 0.782
regulation of adaptive immune response GO:0002819 90 0.768
response to interferon gamma GO:0034341 34 0.743
regulation of t cell proliferation GO:0042129 92 0.741
t helper 1 type immune response GO:0042088 25 0.711
regulation of t cell activation GO:0050863 170 0.702
positive regulation of cytokine production GO:0001819 174 0.701
Mouse
homeostasis of number of cells GO:0048872 210 0.695
immune effector process GO:0002252 321 0.692
regulation of cell activation GO:0050865 289 0.667
positive regulation of t cell activation GO:0050870 101 0.658
antigen processing and presentation of peptide antigen GO:0048002 29 0.644
lymphocyte differentiation GO:0030098 242 0.624
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.610
leukocyte differentiation GO:0002521 342 0.598
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.591
t cell proliferation GO:0042098 120 0.568
myeloid cell differentiation GO:0030099 233 0.568
negative regulation of cell activation GO:0050866 111 0.563
myeloid leukocyte differentiation GO:0002573 119 0.561
activation of immune response GO:0002253 138 0.528
eosinophil activation GO:0043307 1 0.527
negative regulation of immune system process GO:0002683 209 0.507
immune response activating signal transduction GO:0002757 116 0.492
regulation of defense response GO:0031347 233 0.482
extrinsic apoptotic signaling pathway GO:0097191 126 0.479
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.460
positive regulation of lymphocyte activation GO:0051251 140 0.447
response to molecule of bacterial origin GO:0002237 143 0.434
regulation of lymphocyte proliferation GO:0050670 117 0.427
leukocyte mediated immunity GO:0002443 174 0.425
regulation of leukocyte mediated immunity GO:0002703 104 0.425
multicellular organismal signaling GO:0035637 91 0.416
epithelial tube morphogenesis GO:0060562 303 0.409
antigen processing and presentation of exogenous antigen GO:0019884 26 0.406
antigen processing and presentation of exogenous peptide antigen GO:0002478 21 0.402
myeloid leukocyte activation GO:0002274 83 0.393
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.391
antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii GO:0002504 17 0.383
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.380
negative regulation of homeostatic process GO:0032845 71 0.375
erythrocyte differentiation GO:0030218 88 0.371
regulation of antigen processing and presentation GO:0002577 10 0.371
Mouse
immune complex clearance GO:0002434 2 0.368
regulation of lymphocyte activation GO:0051249 240 0.359
negative regulation of t cell proliferation GO:0042130 38 0.358
cytokine production GO:0001816 319 0.354
Mouse
calcium ion transport into cytosol GO:0060402 48 0.348
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.345
negative regulation of eosinophil degranulation GO:0043310 1 0.340
helper t cell chemotaxis GO:0035704 1 0.339
glial cell differentiation GO:0010001 131 0.339
positive regulation of adaptive immune response GO:0002821 61 0.323
alpha beta t cell activation GO:0046631 91 0.320
leukocyte proliferation GO:0070661 172 0.319
signal transduction in absence of ligand GO:0038034 55 0.316
negative regulation of lymphocyte activation GO:0051250 91 0.312
t cell differentiation GO:0030217 174 0.310
positive regulation of t cell extravasation GO:2000409 2 0.307
glycoprotein metabolic process GO:0009100 116 0.298
negative regulation of defense response GO:0031348 77 0.297
hematopoietic stem cell migration GO:0035701 1 0.293
regulation of inflammatory response to antigenic stimulus GO:0002861 21 0.292
cell killing GO:0001906 67 0.278
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.277
ras protein signal transduction GO:0007265 77 0.275
regulation of immune complex clearance by monocytes and macrophages GO:0090264 2 0.275
t cell activation GO:0042110 289 0.274
regulation of monocyte chemotaxis GO:0090025 3 0.274
angiogenesis GO:0001525 201 0.273
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.272
neuronal action potential GO:0019228 54 0.269
regulation of innate immune response GO:0045088 91 0.268
regulation of cell killing GO:0031341 40 0.264
myeloid cell homeostasis GO:0002262 114 0.263
positive regulation of immunological synapse formation GO:2000522 1 0.262
lymphocyte mediated immunity GO:0002449 139 0.261
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.258
cellular response to cytokine stimulus GO:0071345 189 0.253
positive regulation of monocyte extravasation GO:2000439 1 0.250
cation transport GO:0006812 399 0.250
lymphocyte proliferation GO:0046651 164 0.250
regulation of eosinophil degranulation GO:0043309 1 0.249
negative regulation of t cell activation GO:0050868 65 0.245
oligodendrocyte differentiation GO:0048709 53 0.235
positive regulation of t cell costimulation GO:2000525 2 0.234
inflammatory response GO:0006954 244 0.234
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.232
negative regulation of growth GO:0045926 99 0.230
branching morphogenesis of an epithelial tube GO:0048754 159 0.228
response to lipopolysaccharide GO:0032496 128 0.226
positive t cell selection GO:0043368 23 0.225
regulation of cytokine production GO:0001817 266 0.224
Mouse
chemokine mediated signaling pathway GO:0070098 17 0.224
negative regulation of lymphocyte proliferation GO:0050672 45 0.224
leukocyte chemotaxis GO:0030595 69 0.223
calcium ion transport GO:0006816 159 0.222
sequestering of calcium ion GO:0051208 18 0.221
positive regulation of dendritic cell chemotaxis GO:2000510 1 0.219
positive regulation of leukocyte mediated immunity GO:0002705 70 0.219
muscle tissue development GO:0060537 308 0.218
divalent inorganic cation transport GO:0072511 178 0.215
anatomical structure homeostasis GO:0060249 145 0.215
blood vessel morphogenesis GO:0048514 285 0.214
t cell receptor signaling pathway GO:0050852 46 0.214
antigen processing and presentation of peptide antigen via mhc class ii GO:0002495 17 0.212
regulation of cellular amine metabolic process GO:0033238 20 0.211
positive regulation of t cell mediated cytotoxicity GO:0001916 15 0.209
regulation of cytokine biosynthetic process GO:0042035 59 0.207
positive regulation of immune complex clearance by monocytes and macrophages GO:0090265 2 0.206
regulation of ion homeostasis GO:2000021 64 0.206
regulation of membrane potential GO:0042391 192 0.206
antigen receptor mediated signaling pathway GO:0050851 64 0.205
release of sequestered calcium ion into cytosol GO:0051209 42 0.203
cytosolic calcium ion homeostasis GO:0051480 70 0.202
cellular ketone metabolic process GO:0042180 84 0.201
positive regulation of t helper 1 type immune response GO:0002827 12 0.201
cellular response to lipid GO:0071396 145 0.200
cytokine biosynthetic process GO:0042089 68 0.200
t cell extravasation GO:0072683 4 0.197
multicellular organismal homeostasis GO:0048871 164 0.194
regulation of t cell extravasation GO:2000407 3 0.192
neuron migration GO:0001764 122 0.190
peptidyl tyrosine phosphorylation GO:0018108 143 0.189
cell type specific apoptotic process GO:0097285 268 0.188
tissue homeostasis GO:0001894 115 0.187
positive regulation of hematopoietic stem cell migration GO:2000473 1 0.186
alpha beta t cell proliferation GO:0046633 21 0.185
t cell differentiation in thymus GO:0033077 77 0.182
immunoglobulin mediated immune response GO:0016064 69 0.181
defense response to bacterium GO:0042742 119 0.178
Mouse
microglial cell activation involved in immune response GO:0002282 1 0.177
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.176
regulation of leukocyte differentiation GO:1902105 159 0.175
regulation of leukocyte proliferation GO:0070663 121 0.170
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.170
peptidyl amino acid modification GO:0018193 336 0.169
mature dendritic cell differentiation GO:0097029 3 0.168
positive regulation of innate immune response GO:0045089 80 0.165
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.165
regulation of t cell costimulation GO:2000523 2 0.164
regulation of t helper 1 type immune response GO:0002825 17 0.164
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation GO:2000721 2 0.164
regulation of dendritic cell chemotaxis GO:2000508 1 0.162
transmission of nerve impulse GO:0019226 76 0.162
humoral immune response GO:0006959 57 0.161
granulocyte chemotaxis GO:0071621 39 0.161
regulation of ion transport GO:0043269 215 0.158
tissue remodeling GO:0048771 102 0.155
b cell mediated immunity GO:0019724 71 0.153
regulation of cytokine secretion GO:0050707 61 0.151
positive regulation of cytokine secretion GO:0050715 41 0.149
immune complex clearance by monocytes and macrophages GO:0002436 2 0.147
microglia development GO:0014005 2 0.146
regulation of ossification GO:0030278 112 0.144
eosinophil mediated immunity GO:0002447 1 0.144
defense response to other organism GO:0098542 197 0.143
Mouse
leukocyte migration GO:0050900 124 0.143
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.142
Mouse
eosinophil degranulation GO:0043308 1 0.140
positive regulation of homeostatic process GO:0032846 64 0.139
negative regulation of cell proliferation GO:0008285 296 0.139
stem cell differentiation GO:0048863 268 0.138
cytosolic calcium ion transport GO:0060401 48 0.138
action potential GO:0001508 78 0.137
response to organic cyclic compound GO:0014070 198 0.135
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.133
regulation of defense response to virus GO:0050688 18 0.133
morphogenesis of a branching structure GO:0001763 203 0.133
gliogenesis GO:0042063 141 0.133
microglia differentiation GO:0014004 2 0.132
positive regulation of cell migration GO:0030335 109 0.132
striated muscle tissue development GO:0014706 293 0.130
cytokine mediated signaling pathway GO:0019221 115 0.130
lymphocyte migration GO:0072676 26 0.130
positive regulation of cell development GO:0010720 237 0.129
morphogenesis of a branching epithelium GO:0061138 193 0.127
negative regulation of immune effector process GO:0002698 55 0.126
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.126
myd88 independent toll like receptor signaling pathway GO:0002756 3 0.126
cytokine secretion GO:0050663 72 0.123
positive regulation of apoptotic process GO:0043065 217 0.120
regulation of alpha beta t cell activation GO:0046634 53 0.120
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526 1 0.120
cytoplasmic transport GO:0016482 234 0.119
protein secretion GO:0009306 111 0.116
t helper 17 cell chemotaxis GO:0035705 1 0.115
divalent inorganic cation homeostasis GO:0072507 138 0.115
rho protein signal transduction GO:0007266 32 0.114
heart morphogenesis GO:0003007 178 0.113
sequestering of metal ion GO:0051238 19 0.113
membrane organization GO:0061024 245 0.111
regulation of monocyte extravasation GO:2000437 2 0.111
cellular divalent inorganic cation homeostasis GO:0072503 127 0.109
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.108
interleukin 12 secretion GO:0072610 3 0.105
tumor necrosis factor production GO:0032640 50 0.104
Mouse
regulation of lymphocyte mediated immunity GO:0002706 84 0.104
regulation of acute inflammatory response GO:0002673 27 0.104
positive regulation of cell killing GO:0031343 33 0.103
cell activation involved in immune response GO:0002263 126 0.102
gland development GO:0048732 330 0.101
cellular amine metabolic process GO:0044106 44 0.100
positive regulation of nervous system development GO:0051962 221 0.100
interleukin 10 secretion GO:0072608 4 0.099
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.099
regulation of neutrophil chemotaxis GO:0090022 14 0.099
myeloid dendritic cell activation GO:0001773 25 0.098
positive regulation of leukocyte differentiation GO:1902107 86 0.098
divalent metal ion transport GO:0070838 172 0.097
dna metabolic process GO:0006259 303 0.096
regulation of response to wounding GO:1903034 189 0.096
negative regulation of innate immune response GO:0045824 17 0.096
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.095
regulation of t cell mediated cytotoxicity GO:0001914 18 0.094
cell chemotaxis GO:0060326 81 0.094
positive regulation of programmed cell death GO:0043068 218 0.092
g protein coupled receptor signaling pathway GO:0007186 243 0.091
regulation of immunological synapse formation GO:2000520 2 0.090
regulation of cell migration GO:0030334 219 0.090
positive regulation of tumor necrosis factor production GO:0032760 30 0.090
Mouse
regulation of t cell mediated immunity GO:0002709 34 0.090
regulation of vasculature development GO:1901342 88 0.089
t helper cell differentiation GO:0042093 28 0.089
microglial cell activation GO:0001774 3 0.089
macromolecule catabolic process GO:0009057 281 0.089
positive regulation of chemotaxis GO:0050921 38 0.088
cellular calcium ion homeostasis GO:0006874 119 0.088
regulation of interferon gamma production GO:0032649 57 0.087
regulation of growth of symbiont in host GO:0044126 19 0.087
negative regulation of vasculature development GO:1901343 26 0.086
metal ion homeostasis GO:0055065 189 0.086
defense response to virus GO:0051607 68 0.085
inositol lipid mediated signaling GO:0048017 41 0.085
myeloid dendritic cell differentiation GO:0043011 16 0.084
cellular response to lipopolysaccharide GO:0071222 77 0.083
positive regulation of cell motility GO:2000147 116 0.083
telencephalon development GO:0021537 186 0.083
leukocyte homeostasis GO:0001776 79 0.083
myeloid leukocyte mediated immunity GO:0002444 42 0.082
positive regulation of cytokine biosynthetic process GO:0042108 40 0.081
positive regulation of t cell differentiation GO:0045582 52 0.080
monocyte extravasation GO:0035696 2 0.079
thymic t cell selection GO:0045061 22 0.079
positive regulation of alpha beta t cell activation GO:0046635 39 0.078
positive regulation of lymphocyte migration GO:2000403 11 0.077
leukocyte activation involved in immune response GO:0002366 126 0.077
negative regulation of macrophage apoptotic process GO:2000110 3 0.077
carbohydrate derivative biosynthetic process GO:1901137 183 0.076
regulation of myeloid leukocyte mediated immunity GO:0002886 25 0.076
positive regulation of interferon alpha production GO:0032727 4 0.076
neural precursor cell proliferation GO:0061351 121 0.076
interferon beta biosynthetic process GO:0045350 4 0.075
negative regulation of leukocyte differentiation GO:1902106 51 0.074
regulation of interleukin 2 production GO:0032663 28 0.074
negative regulation of synapse assembly GO:0051964 3 0.074
cytokine metabolic process GO:0042107 71 0.074
regulation of interleukin 1 beta secretion GO:0050706 15 0.074
cellular response to biotic stimulus GO:0071216 92 0.074
telencephalon cell migration GO:0022029 55 0.073
bone resorption GO:0045453 38 0.073
ensheathment of neurons GO:0007272 76 0.073
regulation of cytoskeleton organization GO:0051493 122 0.073
b cell homeostasis GO:0001782 34 0.073
regulation of myeloid cell differentiation GO:0045637 96 0.070
immune response regulating signaling pathway GO:0002764 125 0.070
interleukin 1 beta secretion GO:0050702 16 0.070
reactive nitrogen species metabolic process GO:2001057 0 0.070
regulation of angiogenesis GO:0045765 81 0.070
ameboidal type cell migration GO:0001667 128 0.069
positive regulation of secretion GO:0051047 130 0.069
pattern recognition receptor signaling pathway GO:0002221 47 0.069
mapk cascade GO:0000165 281 0.069
Mouse
activation of innate immune response GO:0002218 56 0.068
hematopoietic progenitor cell differentiation GO:0002244 143 0.067
positive regulation of glial cell differentiation GO:0045687 21 0.066
cellular homeostasis GO:0019725 240 0.066
positive regulation of t cell proliferation GO:0042102 52 0.066
cellular response to growth factor stimulus GO:0071363 197 0.066
innate immune response activating signal transduction GO:0002758 50 0.065
regulation of body fluid levels GO:0050878 162 0.065
regulation of type 2 immune response GO:0002828 18 0.064
positive regulation of calcium mediated signaling GO:0050850 15 0.064
embryonic placenta development GO:0001892 98 0.064
negative regulation of angiogenesis GO:0016525 25 0.064
regulation of humoral immune response GO:0002920 22 0.064
positive regulation of immune effector process GO:0002699 107 0.062
myeloid leukocyte migration GO:0097529 57 0.062
negative regulation of leukocyte proliferation GO:0070664 46 0.062
b cell activation GO:0042113 161 0.062
salivary gland development GO:0007431 37 0.062
nucleotide metabolic process GO:0009117 332 0.061
regulation of tumor necrosis factor production GO:0032680 49 0.061
Mouse
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.061
activation of mapk activity GO:0000187 59 0.061
positive regulation of response to cytokine stimulus GO:0060760 11 0.061
myelination GO:0042552 74 0.061
cd4 positive alpha beta t cell activation GO:0035710 45 0.060
response to protozoan GO:0001562 28 0.060
regulation of t cell differentiation GO:0045580 83 0.060
maintenance of location GO:0051235 89 0.060
cd8 positive alpha beta t cell proliferation GO:0035740 1 0.060
myeloid cell activation involved in immune response GO:0002275 34 0.060
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.059
regulation of myeloid leukocyte differentiation GO:0002761 58 0.059
ossification GO:0001503 216 0.059
regulation of protein kinase activity GO:0045859 232 0.059
negative regulation of intracellular signal transduction GO:1902532 167 0.059
ribose phosphate metabolic process GO:0019693 291 0.059
positive regulation of protein modification process GO:0031401 299 0.059
regulation of tumor necrosis factor biosynthetic process GO:0042534 10 0.059
pallium development GO:0021543 120 0.059
regulation of toll like receptor 4 signaling pathway GO:0034143 4 0.059
regulation of cellular amino acid metabolic process GO:0006521 5 0.059
axon ensheathment GO:0008366 76 0.058
positive regulation of secretion by cell GO:1903532 114 0.058
forebrain cell migration GO:0021885 58 0.058
regulation of homeostatic process GO:0032844 182 0.058
i kappab kinase nf kappab signaling GO:0007249 85 0.058
Mouse
lung development GO:0030324 164 0.057
production of molecular mediator of immune response GO:0002440 103 0.057
interleukin 1 secretion GO:0050701 16 0.057
positive thymic t cell selection GO:0045059 13 0.057
positive regulation of lymphocyte proliferation GO:0050671 70 0.056
negative thymic t cell selection GO:0045060 12 0.056
regulation of hematopoietic stem cell migration GO:2000471 1 0.056
organic hydroxy compound metabolic process GO:1901615 203 0.056
negative regulation of phosphate metabolic process GO:0045936 184 0.055
myotube differentiation GO:0014902 105 0.054
b cell proliferation GO:0042100 53 0.054
positive regulation of acute inflammatory response to antigenic stimulus GO:0002866 7 0.054
neuron projection guidance GO:0097485 141 0.054
positive regulation of eosinophil migration GO:2000418 2 0.054
cellular extravasation GO:0045123 17 0.053
response to transforming growth factor beta GO:0071559 88 0.053
carbohydrate metabolic process GO:0005975 230 0.053
regulation of syncytium formation by plasma membrane fusion GO:0060142 23 0.052
glycoprotein biosynthetic process GO:0009101 89 0.052
stem cell development GO:0048864 219 0.052
cellular response to interferon gamma GO:0071346 25 0.052
positive regulation of bone remodeling GO:0046852 13 0.052
t cell migration GO:0072678 19 0.052
regulation of protein secretion GO:0050708 82 0.051
chemotaxis GO:0006935 247 0.051
tumor necrosis factor biosynthetic process GO:0042533 10 0.051
morphogenesis of embryonic epithelium GO:0016331 159 0.051
regulation of metal ion transport GO:0010959 106 0.051
neuroblast differentiation GO:0014016 2 0.050
negative regulation of nervous system development GO:0051961 156 0.050
regulation of mapk cascade GO:0043408 248 0.050
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.050
negative regulation of toll like receptor signaling pathway GO:0034122 14 0.050
monoamine transport GO:0015844 33 0.050
regulation of calcium ion transport GO:0051924 69 0.050
dendritic cell differentiation GO:0097028 26 0.049
regulation of glial cell differentiation GO:0045685 41 0.049
positive regulation of interferon gamma production GO:0032729 39 0.049
response to alcohol GO:0097305 48 0.049
microtubule based process GO:0007017 236 0.048
calcium ion homeostasis GO:0055074 127 0.048
positive regulation of cell death GO:0010942 224 0.048
t cell activation involved in immune response GO:0002286 43 0.048
regulation of myd88 independent toll like receptor signaling pathway GO:0034127 1 0.048
regulation of cellular ketone metabolic process GO:0010565 66 0.048
intracellular receptor signaling pathway GO:0030522 74 0.048
peptidyl lysine modification GO:0018205 77 0.048
embryonic epithelial tube formation GO:0001838 130 0.048
positive regulation of monocyte chemotaxis GO:0090026 2 0.047
calcium mediated signaling GO:0019722 46 0.046
organelle localization GO:0051640 179 0.046
cellular response to molecule of bacterial origin GO:0071219 83 0.046
positive regulation of b cell activation GO:0050871 49 0.046
bone remodeling GO:0046849 53 0.045
germ cell development GO:0007281 185 0.045
response to organonitrogen compound GO:0010243 246 0.045
t helper cell lineage commitment GO:0002295 6 0.045
second messenger mediated signaling GO:0019932 73 0.045
regulation of system process GO:0044057 200 0.045
central nervous system neuron differentiation GO:0021953 162 0.045
macrophage differentiation GO:0030225 20 0.044
extracellular matrix organization GO:0030198 147 0.044
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.044
positive regulation of leukocyte proliferation GO:0070665 73 0.044
neuromuscular process GO:0050905 99 0.044
regulation of reactive oxygen species metabolic process GO:2000377 40 0.043
regulation of interleukin 12 production GO:0032655 30 0.043
positive regulation of cellular catabolic process GO:0031331 148 0.043
negative regulation of signal transduction in absence of ligand GO:1901099 16 0.043
positive regulation of ion transport GO:0043270 65 0.043
t cell mediated cytotoxicity GO:0001913 26 0.042
regulation of apoptotic signaling pathway GO:2001233 197 0.042
positive regulation of kinase activity GO:0033674 155 0.042
regulation of purine nucleotide metabolic process GO:1900542 169 0.042
developmental maturation GO:0021700 193 0.042
regulation of tissue remodeling GO:0034103 38 0.042
negative regulation of myeloid leukocyte differentiation GO:0002762 20 0.042
regulation of cell motility GO:2000145 236 0.042
regulation of protein complex assembly GO:0043254 83 0.042
positive regulation of hydrolase activity GO:0051345 148 0.042
defense response to protozoan GO:0042832 25 0.041
positive regulation of map kinase activity GO:0043406 84 0.041
interferon gamma production GO:0032609 67 0.041
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.041
respiratory system development GO:0060541 190 0.041
forebrain development GO:0030900 302 0.041
natural killer cell mediated cytotoxicity GO:0042267 29 0.041
osteoclast differentiation GO:0030316 62 0.041
digestive tract development GO:0048565 190 0.041
positive regulation of protein kinase activity GO:0045860 144 0.041
regulation of phagocytosis GO:0050764 33 0.041
circadian rhythm GO:0007623 114 0.041
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.040
negative regulation of protein metabolic process GO:0051248 282 0.040
phosphatidylinositol 3 kinase signaling GO:0014065 36 0.040
purine containing compound metabolic process GO:0072521 311 0.040
regulated secretory pathway GO:0045055 32 0.040
cellular response to organic cyclic compound GO:0071407 87 0.040
regulation of b cell activation GO:0050864 81 0.040
leukocyte degranulation GO:0043299 27 0.039
cell maturation GO:0048469 127 0.039
positive regulation of acute inflammatory response GO:0002675 16 0.039
type 2 immune response GO:0042092 23 0.039
oxidation reduction process GO:0055114 342 0.039
apoptotic signaling pathway GO:0097190 306 0.039
positive regulation of antigen receptor mediated signaling pathway GO:0050857 9 0.039
positive regulation of myeloid cell differentiation GO:0045639 43 0.038
regulation of interleukin 10 secretion GO:2001179 4 0.038
cation homeostasis GO:0055080 212 0.038
cellular defense response GO:0006968 6 0.038
phagocytosis GO:0006909 66 0.038
dephosphorylation GO:0016311 129 0.038
small gtpase mediated signal transduction GO:0007264 97 0.038
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.038
epithelial cell proliferation GO:0050673 174 0.038
cerebral cortex cell migration GO:0021795 44 0.038
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.038
regulation of calcium mediated signaling GO:0050848 19 0.037
leukocyte apoptotic process GO:0071887 71 0.037
negative regulation of cellular amine metabolic process GO:0033239 1 0.037
negative regulation of cellular component organization GO:0051129 194 0.037
antigen processing and presentation of exogenous peptide antigen via mhc class ii GO:0019886 14 0.037
protein catabolic process GO:0030163 221 0.037
regulation of striated muscle cell differentiation GO:0051153 81 0.037
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.037
axonogenesis GO:0007409 274 0.037
cellular response to external stimulus GO:0071496 88 0.036
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.036
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.036
Mouse
protein acylation GO:0043543 64 0.036
regulation of inflammatory response GO:0050727 147 0.036
positive regulation of neutrophil migration GO:1902624 12 0.036
mitochondrion distribution GO:0048311 4 0.036
regulation of stress activated mapk cascade GO:0032872 69 0.036
Mouse
interleukin 6 production GO:0032635 58 0.036
Mouse
brown fat cell differentiation GO:0050873 36 0.036
negative regulation of protein modification process GO:0031400 163 0.036
alpha beta t cell differentiation GO:0046632 69 0.036
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.036
regulation of interleukin 1 secretion GO:0050704 15 0.036
regulation of cellular response to growth factor stimulus GO:0090287 82 0.035
detection of yeast GO:0001879 2 0.035
immunoglobulin production GO:0002377 73 0.035
response to steroid hormone GO:0048545 56 0.034
axon guidance GO:0007411 141 0.034
cerebral cortex development GO:0021987 86 0.034
regulation of myd88 dependent toll like receptor signaling pathway GO:0034124 2 0.034
interleukin 1 beta production GO:0032611 30 0.034
regulation of cellular catabolic process GO:0031329 242 0.034
positive regulation of dendritic cell antigen processing and presentation GO:0002606 7 0.034
Mouse
labyrinthine layer development GO:0060711 49 0.034
positive regulation of glycolytic process GO:0045821 4 0.034
positive regulation of protein secretion GO:0050714 52 0.034
reactive oxygen species metabolic process GO:0072593 84 0.034
positive regulation of apoptotic signaling pathway GO:2001235 95 0.034
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.034
regulation of regulated secretory pathway GO:1903305 20 0.033
carbohydrate derivative catabolic process GO:1901136 231 0.033
gonad development GO:0008406 141 0.033
positive regulation of calcium ion transport GO:0051928 27 0.033
aromatic compound catabolic process GO:0019439 286 0.033
b cell activation involved in immune response GO:0002312 50 0.033
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.033
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.033
rhythmic process GO:0048511 174 0.033
circadian temperature homeostasis GO:0060086 2 0.033
interleukin 12 production GO:0032615 32 0.033
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.033
regulation of lymphocyte differentiation GO:0045619 107 0.033
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.033

Ciita disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.249
Human
disease of anatomical entity DOID:7 0 0.249
Human
nervous system disease DOID:863 0 0.114
central nervous system disease DOID:331 0 0.057
neurodegenerative disease DOID:1289 0 0.038
musculoskeletal system disease DOID:17 0 0.033
Human