Mus musculus

81 known processes

Clec4n

C-type lectin domain family 4, member n

(Aliases: Nkcl,Clec6a,Clecsf10)

Clec4n biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of phagocytosis GO:0050766 26 0.995
Mouse
positive regulation of cytokine production GO:0001819 174 0.965
defense response to other organism GO:0098542 197 0.955
leukocyte proliferation GO:0070661 172 0.914
Mouse
lymphocyte proliferation GO:0046651 164 0.910
Mouse
positive regulation of tumor necrosis factor production GO:0032760 30 0.910
Mouse
regulation of mast cell activation GO:0033003 21 0.893
regulation of lymphocyte proliferation GO:0050670 117 0.887
Mouse
regulation of innate immune response GO:0045088 91 0.875
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.866
Mouse
t cell activation GO:0042110 289 0.854
Mouse
regulation of tumor necrosis factor production GO:0032680 49 0.851
Mouse
positive regulation of defense response GO:0031349 124 0.835
detection of fungus GO:0016046 2 0.812
Mouse
defense response to gram positive bacterium GO:0050830 50 0.804
cell chemotaxis GO:0060326 81 0.778
tumor necrosis factor biosynthetic process GO:0042533 10 0.772
Mouse
regulation of defense response GO:0031347 233 0.767
regulation of lymphocyte activation GO:0051249 240 0.762
Mouse
immune effector process GO:0002252 321 0.744
Mouse
regulation of leukocyte mediated immunity GO:0002703 104 0.734
Mouse
regulation of inflammatory response GO:0050727 147 0.726
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.708
Mouse
regulation of leukocyte proliferation GO:0070663 121 0.699
Mouse
positive regulation of leukocyte mediated immunity GO:0002705 70 0.696
Mouse
positive regulation of endocytosis GO:0045807 42 0.689
Mouse
positive regulation of cytokine biosynthetic process GO:0042108 40 0.687
Mouse
response to molecule of bacterial origin GO:0002237 143 0.678
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.667
Mouse
regulation of cytokine production GO:0001817 266 0.667
regulation of interleukin 6 production GO:0032675 55 0.662
serotonin secretion involved in inflammatory response GO:0002442 4 0.655
negative regulation of t cell proliferation GO:0042130 38 0.636
Mouse
regulation of cell activation GO:0050865 289 0.628
Mouse
t cell proliferation GO:0042098 120 0.625
Mouse
negative regulation of adaptive immune response GO:0002820 25 0.609
Mouse
leukocyte differentiation GO:0002521 342 0.606
regulation of b cell mediated immunity GO:0002712 37 0.596
Mouse
positive regulation of t cell activation GO:0050870 101 0.560
positive regulation of secretion by cell GO:1903532 114 0.557
regulation of type ii hypersensitivity GO:0002892 4 0.549
chemotaxis GO:0006935 247 0.546
regulation of type iia hypersensitivity GO:0001796 4 0.540
regulated secretory pathway GO:0045055 32 0.537
activation of immune response GO:0002253 138 0.524
positive regulation of cell activation GO:0050867 158 0.523
tumor necrosis factor production GO:0032640 50 0.517
Mouse
cation transport GO:0006812 399 0.516
Mouse
regulation of t cell proliferation GO:0042129 92 0.512
Mouse
positive regulation of leukocyte proliferation GO:0070665 73 0.502
defense response to bacterium GO:0042742 119 0.502
Mouse
positive regulation of innate immune response GO:0045089 80 0.501
cytokine production GO:0001816 319 0.494
myeloid leukocyte activation GO:0002274 83 0.488
regulation of protein secretion GO:0050708 82 0.480
regulation of vesicle mediated transport GO:0060627 139 0.472
Mouse
cellular response to peptidoglycan GO:0071224 4 0.469
positive regulation of type ii hypersensitivity GO:0002894 4 0.465
cytokine biosynthetic process GO:0042089 68 0.443
Mouse
b cell activation GO:0042113 161 0.427
neutrophil chemotaxis GO:0030593 36 0.421
endocytosis GO:0006897 168 0.412
Mouse
positive regulation of t cell proliferation GO:0042102 52 0.410
i kappab kinase nf kappab signaling GO:0007249 85 0.409
positive regulation of b cell activation GO:0050871 49 0.409
regulation of tumor necrosis factor biosynthetic process GO:0042534 10 0.397
Mouse
mapk cascade GO:0000165 281 0.395
regulation of t cell activation GO:0050863 170 0.394
Mouse
positive regulation of type iii hypersensitivity GO:0001805 3 0.388
lymphocyte mediated immunity GO:0002449 139 0.387
Mouse
mast cell activation GO:0045576 27 0.367
regulation of jnk cascade GO:0046328 62 0.365
positive regulation of lymphocyte activation GO:0051251 140 0.364
response to peptidoglycan GO:0032494 9 0.355
regulation of cell motility GO:2000145 236 0.353
inflammatory response GO:0006954 244 0.349
positive regulation of jnk cascade GO:0046330 46 0.346
negative regulation of leukocyte mediated immunity GO:0002704 29 0.341
Mouse
innate immune response GO:0045087 157 0.339
cellular response to molecule of bacterial origin GO:0071219 83 0.326
leukocyte activation involved in immune response GO:0002366 126 0.320
myeloid leukocyte migration GO:0097529 57 0.320
regulation of response to wounding GO:1903034 189 0.318
regulation of endocytosis GO:0030100 69 0.317
Mouse
regulation of secretion GO:0051046 274 0.315
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.310
Mouse
positive regulation of natural killer cell chemotaxis GO:2000503 1 0.309
negative regulation of immune system process GO:0002683 209 0.298
Mouse
regulation of cellular response to stress GO:0080135 159 0.297
antigen processing and presentation GO:0019882 47 0.296
positive regulation of immunoglobulin mediated immune response GO:0002891 26 0.295
Mouse
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.295
immune response regulating signaling pathway GO:0002764 125 0.294
jnk cascade GO:0007254 72 0.290
b cell proliferation GO:0042100 53 0.283
leukocyte mediated immunity GO:0002443 174 0.281
Mouse
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.281
eosinophil migration GO:0072677 3 0.278
lysosome localization GO:0032418 20 0.268
positive regulation of immune effector process GO:0002699 107 0.267
Mouse
fc epsilon receptor signaling pathway GO:0038095 3 0.263
serotonin production involved in inflammatory response GO:0002351 4 0.261
positive regulation of b cell mediated immunity GO:0002714 26 0.259
Mouse
regulation of lymphocyte mediated immunity GO:0002706 84 0.255
Mouse
g protein coupled purinergic nucleotide receptor signaling pathway GO:0035589 1 0.253
immunoglobulin mediated immune response GO:0016064 69 0.250
Mouse
production of molecular mediator involved in inflammatory response GO:0002532 21 0.248
cell activation involved in immune response GO:0002263 126 0.247
detection of yeast GO:0001879 2 0.246
Mouse
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.243
negative regulation of inflammatory response to antigenic stimulus GO:0002862 10 0.238
adaptive immune response GO:0002250 155 0.237
Mouse
membrane organization GO:0061024 245 0.237
positive regulation of lymphocyte proliferation GO:0050671 70 0.235
mast cell mediated immunity GO:0002448 20 0.234
positive regulation of stress activated mapk cascade GO:0032874 48 0.233
cell recognition GO:0008037 83 0.225
Mouse
positive regulation of intracellular transport GO:0032388 70 0.223
Mouse
cellular response to lipopolysaccharide GO:0071222 77 0.223
cytokine metabolic process GO:0042107 71 0.222
Mouse
regulation of mast cell degranulation GO:0043304 16 0.221
immune response activating signal transduction GO:0002757 116 0.213
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.208
Mouse
regulation of b cell proliferation GO:0030888 39 0.207
regulation of mapk cascade GO:0043408 248 0.207
cellular metal ion homeostasis GO:0006875 151 0.206
Mouse
mast cell activation involved in immune response GO:0002279 20 0.206
leukocyte chemotaxis GO:0030595 69 0.205
toll like receptor 9 signaling pathway GO:0034162 6 0.191
purinergic nucleotide receptor signaling pathway GO:0035590 3 0.190
regulation of stress activated mapk cascade GO:0032872 69 0.188
regulation of cellular ketone metabolic process GO:0010565 66 0.187
cellular lipid metabolic process GO:0044255 323 0.184
metal ion homeostasis GO:0055065 189 0.183
Mouse
granulocyte migration GO:0097530 43 0.180
cytokine secretion GO:0050663 72 0.179
negative regulation of immune effector process GO:0002698 55 0.177
Mouse
positive regulation of adaptive immune response GO:0002821 61 0.176
Mouse
cellular chemical homeostasis GO:0055082 215 0.175
Mouse
positive regulation of protein transport GO:0051222 93 0.175
positive regulation of kinase activity GO:0033674 155 0.175
positive regulation of toll like receptor 9 signaling pathway GO:0034165 2 0.171
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.169
positive regulation of mapk cascade GO:0043410 170 0.168
reactive nitrogen species metabolic process GO:2001057 0 0.165
negative regulation of lymphocyte proliferation GO:0050672 45 0.165
Mouse
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.164
response to organonitrogen compound GO:0010243 246 0.164
regulation of monocyte chemotaxis GO:0090025 3 0.162
positive regulation of tumor necrosis factor biosynthetic process GO:0042535 8 0.161
Mouse
response to drug GO:0042493 75 0.158
regulation of protein transport GO:0051223 163 0.157
positive regulation of secretion GO:0051047 130 0.157
regulation of leukocyte differentiation GO:1902105 159 0.153
nitrogen compound transport GO:0071705 271 0.153
detection of other organism GO:0098543 8 0.152
Mouse
positive regulation of monocyte chemotaxis GO:0090026 2 0.148
negative regulation of hypersensitivity GO:0002884 3 0.147
regulation of protein kinase activity GO:0045859 232 0.146
detection of bacterium GO:0016045 7 0.145
Mouse
alpha beta t cell activation GO:0046631 91 0.144
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.143
regulation of granulocyte macrophage colony stimulating factor biosynthetic process GO:0045423 2 0.143
stress activated mapk cascade GO:0051403 80 0.140
regulation of secretion by cell GO:1903530 249 0.139
thymic t cell selection GO:0045061 22 0.139
regulation of b cell activation GO:0050864 81 0.137
regulation of type iii hypersensitivity GO:0001803 3 0.136
regulation of natural killer cell chemotaxis GO:2000501 1 0.133
divalent inorganic cation transport GO:0072511 178 0.133
Mouse
reactive oxygen species metabolic process GO:0072593 84 0.132
serotonin secretion by mast cell GO:0002552 1 0.132
regulation of toll like receptor 9 signaling pathway GO:0034163 3 0.132
negative regulation of inflammatory response GO:0050728 61 0.130
histamine production involved in inflammatory response GO:0002349 1 0.129
humoral immune response mediated by circulating immunoglobulin GO:0002455 14 0.127
Mouse
positive regulation of inflammatory response GO:0050729 47 0.124
cellular ketone metabolic process GO:0042180 84 0.124
regulation of body fluid levels GO:0050878 162 0.123
activation of mapk activity GO:0000187 59 0.122
rho protein signal transduction GO:0007266 32 0.122
nitric oxide metabolic process GO:0046209 25 0.122
regulation of adaptive immune response GO:0002819 90 0.121
Mouse
mast cell degranulation GO:0043303 19 0.120
response to lipopolysaccharide GO:0032496 128 0.119
stress activated protein kinase signaling cascade GO:0031098 81 0.119
regulation of protein serine threonine kinase activity GO:0071900 157 0.119
cellular response to biotic stimulus GO:0071216 92 0.118
positive regulation of type iia hypersensitivity GO:0001798 4 0.115
cation homeostasis GO:0055080 212 0.115
Mouse
reactive oxygen species biosynthetic process GO:1903409 8 0.114
regulation of myeloid leukocyte mediated immunity GO:0002886 25 0.113
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.113
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.112
detection of stimulus GO:0051606 84 0.112
Mouse
cellular homeostasis GO:0019725 240 0.112
Mouse
positive regulation of leukocyte degranulation GO:0043302 10 0.111
organic hydroxy compound transport GO:0015850 93 0.110
regulation of antigen processing and presentation GO:0002577 10 0.107
negative regulation of cell activation GO:0050866 111 0.107
Mouse
regulation of immunoglobulin mediated immune response GO:0002889 37 0.105
Mouse
positive regulation of protein secretion GO:0050714 52 0.105
regulation of intracellular transport GO:0032386 159 0.105
Mouse
interleukin 2 production GO:0032623 33 0.104
protein kinase b signaling GO:0043491 74 0.104
negative regulation of t cell mediated immunity GO:0002710 9 0.101
Mouse
regulation of interleukin 2 production GO:0032663 28 0.100
regulation of fat cell differentiation GO:0045598 81 0.099
calcium ion transport GO:0006816 159 0.099
Mouse
regulation of thymocyte migration GO:2000410 2 0.098
positive regulation of cytokine secretion GO:0050715 41 0.098
serotonin secretion GO:0001820 8 0.095
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.095
phagocytosis recognition GO:0006910 12 0.094
Mouse
response to molecule of fungal origin GO:0002238 4 0.093
cellular ion homeostasis GO:0006873 165 0.093
Mouse
monoamine transport GO:0015844 33 0.093
myeloid leukocyte mediated immunity GO:0002444 42 0.092
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.092
Mouse
positive regulation of map kinase activity GO:0043406 84 0.092
positive regulation of granulocyte macrophage colony stimulating factor biosynthetic process GO:0045425 2 0.091
t cell differentiation GO:0030217 174 0.091
leukocyte migration GO:0050900 124 0.090
positive regulation of transferase activity GO:0051347 167 0.088
negative regulation of type i hypersensitivity GO:0001811 1 0.087
regulation of cellular amine metabolic process GO:0033238 20 0.086
positive regulation of hematopoietic stem cell migration GO:2000473 1 0.085
regulation of t cell mediated immunity GO:0002709 34 0.084
Mouse
cellular response to organonitrogen compound GO:0071417 145 0.084
integrin mediated signaling pathway GO:0007229 27 0.083
regulation of homeostatic process GO:0032844 182 0.083
Mouse
innate immune response activating signal transduction GO:0002758 50 0.080
serotonin transport GO:0006837 11 0.080
negative regulation of mast cell degranulation GO:0043305 4 0.080
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.080
regulation of leukocyte apoptotic process GO:2000106 56 0.080
exocytosis GO:0006887 121 0.079
negative regulation of homeostatic process GO:0032845 71 0.077
Mouse
regulation of phagocytosis GO:0050764 33 0.076
Mouse
regulation of humoral immune response mediated by circulating immunoglobulin GO:0002923 10 0.075
Mouse
regulation of t cell differentiation GO:0045580 83 0.074
regulation of ion transport GO:0043269 215 0.073
Mouse
regulation of type i hypersensitivity GO:0001810 4 0.073
regulation of cell migration GO:0030334 219 0.072
positive regulation of protein phosphorylation GO:0001934 242 0.072
detection of molecule of bacterial origin GO:0032490 2 0.072
organic anion transport GO:0015711 137 0.071
wound healing GO:0042060 157 0.071
positive regulation of b cell proliferation GO:0030890 24 0.071
negative regulation of lymphocyte mediated immunity GO:0002707 21 0.070
Mouse
regulation of transferase activity GO:0051338 263 0.070
production of molecular mediator of immune response GO:0002440 103 0.070
granulocyte macrophage colony stimulating factor biosynthetic process GO:0042253 2 0.070
positive regulation of mast cell activation involved in immune response GO:0033008 10 0.069
acute inflammatory response to antigenic stimulus GO:0002438 12 0.069
regulation of erk1 and erk2 cascade GO:0070372 71 0.068
positive regulation of exocytosis GO:0045921 20 0.068
regulation of granulocyte macrophage colony stimulating factor production GO:0032645 3 0.068
regulation of metal ion transport GO:0010959 106 0.067
Mouse
regulation of interleukin 10 production GO:0032653 21 0.066
regulation of hypersensitivity GO:0002883 10 0.066
phagocytosis GO:0006909 66 0.065
Mouse
myeloid cell differentiation GO:0030099 233 0.065
purine ribonucleotide metabolic process GO:0009150 290 0.065
membrane invagination GO:0010324 17 0.064
ras protein signal transduction GO:0007265 77 0.064
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.064
antigen processing and presentation of peptide antigen via mhc class i GO:0002474 9 0.064
regulation of map kinase activity GO:0043405 120 0.064
fat cell differentiation GO:0045444 160 0.063
second messenger mediated signaling GO:0019932 73 0.063
regulation of exocytosis GO:0017157 61 0.063
maintenance of location GO:0051235 89 0.062
positive regulation of cytokine production involved in immune response GO:0002720 19 0.062
regulation of immunoglobulin production in mucosal tissue GO:2000557 1 0.062
cellular amine metabolic process GO:0044106 44 0.062
type i hypersensitivity GO:0016068 4 0.061
regulation of acute inflammatory response GO:0002673 27 0.061
positive regulation of response to wounding GO:1903036 66 0.061
immunoglobulin transcytosis in epithelial cells GO:0002414 2 0.061
cytosolic calcium ion homeostasis GO:0051480 70 0.060
Mouse
positive regulation of mast cell degranulation GO:0043306 10 0.060
regulation of cellular amino acid metabolic process GO:0006521 5 0.060
negative regulation of mapk cascade GO:0043409 65 0.060
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.060
release of sequestered calcium ion into cytosol GO:0051209 42 0.060
Mouse
t cell selection GO:0045058 34 0.059
cell cell recognition GO:0009988 44 0.059
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.058
b cell mediated immunity GO:0019724 71 0.058
Mouse
regulation of cellular catabolic process GO:0031329 242 0.058
neutrophil activation involved in immune response GO:0002283 8 0.057
regulation of alpha beta t cell activation GO:0046634 53 0.057
cell adhesion GO:0007155 329 0.056
positive regulation of protein kinase activity GO:0045860 144 0.055
cell cell adhesion GO:0098609 41 0.055
positive regulation of dendritic cell dendrite assembly GO:2000549 1 0.055
myeloid cell activation involved in immune response GO:0002275 34 0.055
organic acid biosynthetic process GO:0016053 86 0.054
negative regulation of leukocyte proliferation GO:0070664 46 0.054
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.054
platelet activation GO:0030168 40 0.054
thymocyte migration GO:0072679 2 0.053
cellular amino acid metabolic process GO:0006520 103 0.053
antigen processing and presentation of exogenous antigen GO:0019884 26 0.053
regulation of kinase activity GO:0043549 249 0.052
positive regulation of myeloid leukocyte mediated immunity GO:0002888 14 0.052
regulation of interferon gamma production GO:0032649 57 0.052
regulation of cytokine secretion GO:0050707 61 0.051
regulation of leukocyte degranulation GO:0043300 20 0.051
regulation of adiponectin secretion GO:0070163 2 0.051
positive regulation of leukocyte differentiation GO:1902107 86 0.050
granulocyte chemotaxis GO:0071621 39 0.050
antigen processing and presentation of exogenous peptide antigen via mhc class i GO:0042590 6 0.050
positive regulation of cell migration GO:0030335 109 0.050
positive regulation of cell motility GO:2000147 116 0.049
positive regulation of interleukin 2 production GO:0032743 19 0.049
activation of innate immune response GO:0002218 56 0.049
response to organic cyclic compound GO:0014070 198 0.049
cellular divalent inorganic cation homeostasis GO:0072503 127 0.049
Mouse
regulation of myeloid cell apoptotic process GO:0033032 19 0.049
erk1 and erk2 cascade GO:0070371 77 0.049
heterocycle catabolic process GO:0046700 280 0.048
regulation of inflammatory response to antigenic stimulus GO:0002861 21 0.048
positive regulation of interleukin 6 production GO:0032755 37 0.048
inflammatory response to antigenic stimulus GO:0002437 30 0.048
cellular response to insulin stimulus GO:0032869 78 0.048
cellular response to cytokine stimulus GO:0071345 189 0.047
negative regulation of macrophage apoptotic process GO:2000110 3 0.047
neutrophil migration GO:1990266 37 0.047
regulation of mast cell activation involved in immune response GO:0033006 17 0.047
leukocyte degranulation GO:0043299 27 0.047
negative regulation of cell proliferation GO:0008285 296 0.047
Mouse
positive regulation of thymocyte migration GO:2000412 2 0.046
cellular nitrogen compound catabolic process GO:0044270 280 0.046
adiponectin secretion GO:0070162 2 0.046
activation of jun kinase activity GO:0007257 15 0.046
positive regulation of calcium ion transport GO:0051928 27 0.046
Mouse
granulocyte macrophage colony stimulating factor production GO:0032604 3 0.046
positive regulation of eosinophil migration GO:2000418 2 0.046
regulation of protein localization GO:0032880 231 0.045
regulation of lymphocyte differentiation GO:0045619 107 0.045
immunoglobulin production GO:0002377 73 0.045
blood vessel morphogenesis GO:0048514 285 0.045
toll like receptor 7 signaling pathway GO:0034154 4 0.045
positive regulation of homeostatic process GO:0032846 64 0.045
Mouse
defense response to virus GO:0051607 68 0.044
amine metabolic process GO:0009308 45 0.043
antimicrobial peptide production GO:0002775 2 0.043
antigen processing and presentation of peptide antigen via mhc class ii GO:0002495 17 0.043
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.042
blood coagulation GO:0007596 76 0.042
fc receptor mediated stimulatory signaling pathway GO:0002431 4 0.042
cellular response to molecule of fungal origin GO:0071226 2 0.041
regulation of myeloid leukocyte differentiation GO:0002761 58 0.041
inorganic cation transmembrane transport GO:0098662 207 0.041
metanephric glomerular visceral epithelial cell development GO:0072249 2 0.041
leukocyte mediated cytotoxicity GO:0001909 62 0.040
ion transmembrane transport GO:0034220 361 0.040
interleukin 6 production GO:0032635 58 0.040
peptide transport GO:0015833 133 0.040
negative regulation of intracellular signal transduction GO:1902532 167 0.040
negative regulation of serotonin secretion GO:0014063 2 0.039
response to peptide GO:1901652 136 0.039
cellular response to lipid GO:0071396 145 0.039
cdc42 protein signal transduction GO:0032488 0 0.038
regulation of chemotaxis GO:0050920 53 0.038
cd4 positive alpha beta t cell proliferation GO:0035739 2 0.038
type iii hypersensitivity GO:0001802 3 0.038
g protein coupled receptor signaling pathway GO:0007186 243 0.038
regulation of interleukin 2 biosynthetic process GO:0045076 13 0.038
sensory perception GO:0007600 245 0.038
macrophage chemotaxis GO:0048246 14 0.038
purinergic receptor signaling pathway GO:0035587 7 0.038
inorganic ion transmembrane transport GO:0098660 234 0.038
positive regulation of macrophage chemotaxis GO:0010759 5 0.037
osteoclast differentiation GO:0030316 62 0.037
carbohydrate derivative biosynthetic process GO:1901137 183 0.037
regulation of protein kinase b signaling GO:0051896 56 0.037
carbohydrate homeostasis GO:0033500 128 0.037
detection of peptidoglycan GO:0032499 1 0.037
positive regulation of granulocyte macrophage colony stimulating factor production GO:0032725 3 0.036
interleukin 3 production GO:0032632 3 0.036
lipid biosynthetic process GO:0008610 179 0.036
lipid modification GO:0030258 65 0.036
leukocyte apoptotic process GO:0071887 71 0.036
antibacterial peptide biosynthetic process GO:0002780 2 0.036
regulation of neutrophil chemotaxis GO:0090022 14 0.036
monosaccharide metabolic process GO:0005996 106 0.035
cellular carbohydrate metabolic process GO:0044262 119 0.035
interleukin 12 secretion GO:0072610 3 0.035
organic cyclic compound catabolic process GO:1901361 295 0.035
divalent inorganic cation homeostasis GO:0072507 138 0.035
Mouse
regulation of calcium ion transport GO:0051924 69 0.035
Mouse
leukocyte homeostasis GO:0001776 79 0.035
chemokine production GO:0032602 34 0.034
negative regulation of phagocytosis GO:0050765 4 0.034
regulation of chemokine production GO:0032642 30 0.034
regulation of establishment of protein localization GO:0070201 181 0.034
regulation of production of molecular mediator of immune response GO:0002700 65 0.034
fc receptor signaling pathway GO:0038093 6 0.033
cation transmembrane transport GO:0098655 266 0.033
interleukin 10 production GO:0032613 23 0.033
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.033
cell type specific apoptotic process GO:0097285 268 0.033
regulation of neuron death GO:1901214 134 0.032
positive regulation of interleukin 10 production GO:0032733 12 0.032
nitric oxide biosynthetic process GO:0006809 25 0.032
skeletal system development GO:0001501 356 0.032
detection of biotic stimulus GO:0009595 10 0.032
Mouse
urogenital system development GO:0001655 261 0.032
positive regulation of acute inflammatory response to antigenic stimulus GO:0002866 7 0.032
tissue homeostasis GO:0001894 115 0.032
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.031
regulation of blood coagulation GO:0030193 28 0.031
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.031
response to dsrna GO:0043331 30 0.031
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.031
positive regulation of nucleotide metabolic process GO:0045981 114 0.031
positive regulation of immunoglobulin production in mucosal tissue GO:2000558 1 0.031
platelet degranulation GO:0002576 6 0.031
interleukin 2 biosynthetic process GO:0042094 15 0.031
glucose homeostasis GO:0042593 128 0.031
placenta development GO:0001890 140 0.031
negative regulation of map kinase activity GO:0043407 34 0.031
calcium mediated signaling GO:0019722 46 0.030
hypersensitivity GO:0002524 10 0.030
positive regulation of apoptotic process GO:0043065 217 0.030
purine nucleoside catabolic process GO:0006152 205 0.030
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.030
divalent metal ion transport GO:0070838 172 0.030
Mouse
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 0.030
Mouse
receptor mediated endocytosis GO:0006898 51 0.030
ribonucleoside metabolic process GO:0009119 245 0.029
detection of lipoteichoic acid GO:0070392 1 0.029
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.029
Mouse
positive regulation of antimicrobial peptide production GO:0002225 1 0.029
protein maturation GO:0051604 176 0.029
b cell differentiation GO:0030183 78 0.029
mature dendritic cell differentiation GO:0097029 3 0.029
negative regulation of t cell activation GO:0050868 65 0.029
Mouse
organ or tissue specific immune response GO:0002251 13 0.029
positive regulation of t helper 2 cell cytokine production GO:2000553 3 0.029
regulation of hormone levels GO:0010817 211 0.029
antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii GO:0002504 17 0.029
homeostasis of number of cells GO:0048872 210 0.028
positive regulation of nitric oxide biosynthetic process GO:0045429 14 0.028
sequestering of calcium ion GO:0051208 18 0.028
regulation of system process GO:0044057 200 0.028
immunoglobulin production in mucosal tissue GO:0002426 3 0.028
nucleoside phosphate metabolic process GO:0006753 338 0.028
myeloid leukocyte differentiation GO:0002573 119 0.028
dna alkylation GO:0006305 43 0.028
positive regulation of mast cell activation GO:0033005 12 0.028
response to metal ion GO:0010038 47 0.028
fatty acid metabolic process GO:0006631 121 0.028
small molecule biosynthetic process GO:0044283 132 0.028
regulation of ras protein signal transduction GO:0046578 114 0.027
negative regulation of cellular protein metabolic process GO:0032269 247 0.027
mature natural killer cell chemotaxis GO:0035782 1 0.027
toll like receptor signaling pathway GO:0002224 38 0.027
negative regulation of regulated secretory pathway GO:1903306 7 0.027
sequestering of metal ion GO:0051238 19 0.027
regulation of ion homeostasis GO:2000021 64 0.027
Mouse
negative regulation of humoral immune response mediated by circulating immunoglobulin GO:0002924 3 0.027
regulation of toll like receptor 2 signaling pathway GO:0034135 3 0.027
morphogenesis of a branching structure GO:0001763 203 0.027
muscle cell differentiation GO:0042692 261 0.026
antigen receptor mediated signaling pathway GO:0050851 64 0.026
glycoprotein metabolic process GO:0009100 116 0.026
purine nucleoside metabolic process GO:0042278 241 0.026
response to yeast GO:0001878 6 0.026
Mouse
single organism cell adhesion GO:0098602 156 0.025
pattern recognition receptor signaling pathway GO:0002221 47 0.025
cellular response to drug GO:0035690 15 0.025
t helper 2 cell cytokine production GO:0035745 4 0.025
cellular calcium ion homeostasis GO:0006874 119 0.025
Mouse
lipid storage GO:0019915 36 0.025
t cell mediated immunity GO:0002456 50 0.025
Mouse
antigen processing and presentation of exogenous peptide antigen GO:0002478 21 0.025
response to oxidative stress GO:0006979 123 0.025
regulation of b cell differentiation GO:0045577 23 0.025
positive regulation of acute inflammatory response GO:0002675 16 0.025
peptidyl amino acid modification GO:0018193 336 0.025
plasma membrane organization GO:0007009 90 0.025
transition metal ion transport GO:0000041 38 0.025
ribose phosphate metabolic process GO:0019693 291 0.025
dna metabolic process GO:0006259 303 0.025
organelle localization GO:0051640 179 0.025
platelet derived growth factor receptor alpha signaling pathway GO:0035790 3 0.024
regulation of antimicrobial peptide biosynthetic process GO:0002805 1 0.024

Clec4n disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease by infectious agent DOID:0050117 0 0.840
cancer DOID:162 0 0.043
disease of cellular proliferation DOID:14566 0 0.043
organ system cancer DOID:0050686 0 0.043