IMP

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Mus musculus

19 genes annotated in mouse

positive regulation of cytokine production involved in immune response

Any process that activates or increases the frequency, rate, or extent of cytokine production that contributes to an immune response.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of cytokine production involved in immune response"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of cytokine production involved in immune response" (in gray)

Name	Description	Probability	Func Analog Organism
Tnf	tumor necrosis factor	0.962
Ccl2	chemokine (C-C motif) ligand 2	0.955
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.900
Il10	interleukin 10	0.725
Cd40	CD40 antigen	0.713	Mouse
Ccr2	chemokine (C-C motif) receptor 2	0.682
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.472
Cd14	CD14 antigen	0.403
Traf6	TNF receptor-associated factor 6	0.334	Human
Lta	lymphotoxin A	0.333
Lyz2	lysozyme 2	0.321
Ikbkg	inhibitor of kappaB kinase gamma	0.297
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.272
H2-Aa	histocompatibility 2, class II antigen A, alpha	0.224
Cxcl2	chemokine (C-X-C motif) ligand 2	0.206
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.197	Human
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.196
Birc3	baculoviral IAP repeat-containing 3	0.191
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.183
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.178
Spp1	secreted phosphoprotein 1	0.171
Ccr1	chemokine (C-C motif) receptor 1	0.168
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.167	Mouse
Myd88	myeloid differentiation primary response gene 88	0.157
Il1r1	interleukin 1 receptor, type I	0.156
Cd44	CD44 antigen	0.154
Tlr2	toll-like receptor 2	0.154
Apoe	apolipoprotein E	0.145
Ifng	interferon gamma	0.145
Irg1	immunoresponsive gene 1	0.129
Ptgs2	prostaglandin-endoperoxide synthase 2	0.125
Ccl7	chemokine (C-C motif) ligand 7	0.125	Mouse
Ubd	ubiquitin D	0.121
Ccl4	chemokine (C-C motif) ligand 4	0.120	Mouse
Ptprc	protein tyrosine phosphatase, receptor type, C	0.118
Ccr5	chemokine (C-C motif) receptor 5	0.112
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.112
Cxcl13	chemokine (C-X-C motif) ligand 13	0.107
C3	complement component 3	0.106
Mmp12	matrix metallopeptidase 12	0.101
Btk	Bruton agammaglobulinemia tyrosine kinase	0.100
Fcgr1	Fc receptor, IgG, high affinity I	0.100
Ccl12	chemokine (C-C motif) ligand 12	0.099	Mouse
Ccl3	chemokine (C-C motif) ligand 3	0.098	Mouse
Tnfrsf13b	tumor necrosis factor receptor superfamily, member 13b	0.096
H2-Eb1	histocompatibility 2, class II antigen E beta	0.095
Ccl22	chemokine (C-C motif) ligand 22	0.093
Ccl8	chemokine (C-C motif) ligand 8	0.091
Ikbkb	inhibitor of kappaB kinase beta	0.091
C3ar1	complement component 3a receptor 1	0.086
Il1rn	interleukin 1 receptor antagonist	0.085
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.082
Il1b	interleukin 1 beta	0.081
Il2rg	interleukin 2 receptor, gamma chain	0.078
H2-Ab1	histocompatibility 2, class II antigen A, beta 1	0.076
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.066
Vdr	vitamin D receptor	0.064
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.063
Siglece	sialic acid binding Ig-like lectin E	0.063
Clec4n	C-type lectin domain family 4, member n	0.062
Pdcd1lg2	programmed cell death 1 ligand 2	0.060
Hcst	hematopoietic cell signal transducer	0.058
Msr1	macrophage scavenger receptor 1	0.058
Cxcl9	chemokine (C-X-C motif) ligand 9	0.055
Folr2	folate receptor 2 (fetal)	0.054
Tcra	T-cell receptor alpha chain	0.053
Lag3	lymphocyte-activation gene 3	0.051
Irf7	interferon regulatory factor 7	0.051
Mmp13	matrix metallopeptidase 13	0.051
Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	0.051
Cxcl10	chemokine (C-X-C motif) ligand 10	0.050
Ccr7	chemokine (C-C motif) receptor 7	0.049
Itgax	integrin alpha X	0.049
Cd28	CD28 antigen	0.048
S1pr2	sphingosine-1-phosphate receptor 2	0.047
Gzma	granzyme A	0.046
Ltb	lymphotoxin B	0.046
Ctsw	cathepsin W	0.045
Il7r	interleukin 7 receptor	0.044
Akt1	thymoma viral proto-oncogene 1	0.043	Mouse
Fcgr3	Fc receptor, IgG, low affinity III	0.041
Csf1	colony stimulating factor 1 (macrophage)	0.040
Nos2	nitric oxide synthase 2, inducible	0.040
Ch25h	cholesterol 25-hydroxylase	0.039
Slamf8	SLAM family member 8	0.036
AF251705	cDNA sequence AF251705	0.035
Pparg	peroxisome proliferator activated receptor gamma	0.035
Il2rb	interleukin 2 receptor, beta chain	0.034
Slc12a6	solute carrier family 12, member 6	0.034
Socs1	suppressor of cytokine signaling 1	0.034
Zbp1	Z-DNA binding protein 1	0.034
Casp1	caspase 1	0.034
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.033
Cd33	CD33 antigen	0.033
Clec7a	C-type lectin domain family 7, member a	0.033
Ilk	integrin linked kinase	0.032
Irak1	interleukin-1 receptor-associated kinase 1	0.030
Slamf9	SLAM family member 9	0.030
Cx3cr1	chemokine (C-X3-C) receptor 1	0.029
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.028
Igh	immunoglobulin heavy chain complex	0.028
Lck	lymphocyte protein tyrosine kinase	0.028
Ticam1	toll-like receptor adaptor molecule 1	0.027
Ccl9	chemokine (C-C motif) ligand 9	0.027	Mouse
Il6	interleukin 6	0.027
Irak3	interleukin-1 receptor-associated kinase 3	0.027
Calcrl	calcitonin receptor-like	0.027
Batf2	basic leucine zipper transcription factor, ATF-like 2	0.027
Selp	selectin, platelet	0.026
Sh2d2a	SH2 domain protein 2A	0.026
Aoah	acyloxyacyl hydrolase	0.026
H2-DMa	histocompatibility 2, class II, locus DMa	0.025
Ltbr	lymphotoxin B receptor	0.024	Mouse
Clec4d	C-type lectin domain family 4, member d	0.024
Ccl6	chemokine (C-C motif) ligand 6	0.024	Mouse
Mx2	myxovirus (influenza virus) resistance 2	0.024
Xcl1	chemokine (C motif) ligand 1	0.024
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.024
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.023
Cd86	CD86 antigen	0.023
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.023
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.023	Mouse
Mmp3	matrix metallopeptidase 3	0.023
Retnla	resistin like alpha	0.023
Bcl3	B-cell leukemia/lymphoma 3	0.021
Tifa	TRAF-interacting protein with forkhead-associated domain	0.021
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.021
Fas	Fas (TNF receptor superfamily member 6)	0.021
Ciita	class II transactivator	0.021
Cxcl1	chemokine (C-X-C motif) ligand 1	0.021
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.020
Ccl24	chemokine (C-C motif) ligand 24	0.020	Mouse
Gzmb	granzyme B	0.020
Dab2	disabled homolog 2 (Drosophila)	0.020
Lilrb3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.019
Il15	interleukin 15	0.019
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.019
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.019
Kdr	kinase insert domain protein receptor	0.018
Lyz1	lysozyme 1	0.018
Cav1	caveolin 1, caveolae protein	0.018
Ikzf1	IKAROS family zinc finger 1	0.018
Mapkapk2	MAP kinase-activated protein kinase 2	0.017
Oas1b	2'-5' oligoadenylate synthetase 1B	0.017
Ldb3	LIM domain binding 3	0.017
Akt2	thymoma viral proto-oncogene 2	0.017	Mouse
Il7	interleukin 7	0.016
Oasl1	2'-5' oligoadenylate synthetase-like 1	0.016
Il1a	interleukin 1 alpha	0.016
Grb7	growth factor receptor bound protein 7	0.016
Slfn3	schlafen 3	0.016
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.016
Mcoln2	mucolipin 2	0.015
Hck	hemopoietic cell kinase	0.015
Pik3cg	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.015
Ifngr1	interferon gamma receptor 1	0.015
Ms4a8a	membrane-spanning 4-domains, subfamily A, member 8A	0.015
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.015
Nkg7	natural killer cell group 7 sequence	0.015
Icam1	intercellular adhesion molecule 1	0.015
Oas3	2'-5' oligoadenylate synthetase 3	0.015
Tnfrsf18	tumor necrosis factor receptor superfamily, member 18	0.015
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.015
Ldlr	low density lipoprotein receptor	0.015
Prkce	protein kinase C, epsilon	0.015
Gpr35	G protein-coupled receptor 35	0.014
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.014
Gzmc	granzyme C	0.014
Muc13	mucin 13, epithelial transmembrane	0.014
Tlr5	toll-like receptor 5	0.014	Mouse
Stat3	signal transducer and activator of transcription 3	0.014
Sfpi1	SFFV proviral integration 1	0.014
Ccl11	chemokine (C-C motif) ligand 11	0.014	Mouse
Il18r1	interleukin 18 receptor 1	0.014
Ccr6	chemokine (C-C motif) receptor 6	0.014
Cxcr5	chemokine (C-X-C motif) receptor 5	0.014
Bcl2a1d	B-cell leukemia/lymphoma 2 related protein A1d	0.014
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.014
Cacna1b	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.014
Ncf4	neutrophil cytosolic factor 4	0.014
Slamf7	SLAM family member 7	0.013
Havcr2	hepatitis A virus cellular receptor 2	0.013
5430435G22Rik	RIKEN cDNA 5430435G22 gene	0.013
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.013
Ms4a7	membrane-spanning 4-domains, subfamily A, member 7	0.013
Kcnj10	potassium inwardly-rectifying channel, subfamily J, member 10	0.013
Cd27	CD27 antigen	0.013
Lilrb4	leukocyte immunoglobulin-like receptor, subfamily B, member 4	0.013
Tnfsf8	tumor necrosis factor (ligand) superfamily, member 8	0.013
Gpr84	G protein-coupled receptor 84	0.013
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.013
Ms4a6d	membrane-spanning 4-domains, subfamily A, member 6D	0.013
Gm11428	predicted gene 11428	0.013
Npy2r	neuropeptide Y receptor Y2	0.013
Fasl	Fas ligand (TNF superfamily, member 6)	0.013
Klrg1	killer cell lectin-like receptor subfamily G, member 1	0.013
Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.013
Cxcl16	chemokine (C-X-C motif) ligand 16	0.012
Ltc4s	leukotriene C4 synthase	0.012
Cd8a	CD8 antigen, alpha chain	0.012
Rhoh	ras homolog gene family, member H	0.012
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.012
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.012
Ccl20	chemokine (C-C motif) ligand 20	0.012
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.012
Fyn	Fyn proto-oncogene	0.012
Ly9	lymphocyte antigen 9	0.012
Nlrp3	NLR family, pyrin domain containing 3	0.012
H2-M10.1	histocompatibility 2, M region locus 10.1	0.012
Hpgds	hematopoietic prostaglandin D synthase	0.012
Epsti1	epithelial stromal interaction 1 (breast)	0.012
Cdh5	cadherin 5	0.012
Il1rl1	interleukin 1 receptor-like 1	0.012
Ly86	lymphocyte antigen 86	0.011
Ly6i	lymphocyte antigen 6 complex, locus I	0.011
Jak3	Janus kinase 3	0.011
Timp1	tissue inhibitor of metalloproteinase 1	0.011
Plau	plasminogen activator, urokinase	0.011
Serpinb9b	serine (or cysteine) peptidase inhibitor, clade B, member 9b	0.011
Traf2	TNF receptor-associated factor 2	0.011	Human
Cldn5	claudin 5	0.011
Fabp4	fatty acid binding protein 4, adipocyte	0.011
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.011
Trafd1	TRAF type zinc finger domain containing 1	0.011
Gna12	guanine nucleotide binding protein, alpha 12	0.011
Slpi	secretory leukocyte peptidase inhibitor	0.011
Cd209b	CD209b antigen	0.011
Emcn	endomucin	0.011
Lpl	lipoprotein lipase	0.011
Irf4	interferon regulatory factor 4	0.011
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.011
Il18rap	interleukin 18 receptor accessory protein	0.010
Il12b	interleukin 12b	0.010
Tlr4	toll-like receptor 4	0.010
Clec4b1	C-type lectin domain family 4, member b1	0.010
Slc39a7	solute carrier family 39 (zinc transporter), member 7	0.010
Sytl3	synaptotagmin-like 3	0.010
Tbx21	T-box 21	0.010
Eltd1	EGF, latrophilin seven transmembrane domain containing 1	0.010
Cd72	CD72 antigen	0.010
Snx20	sorting nexin 20	0.010
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.010
Pdcd1	programmed cell death 1	0.010
Smad1	MAD homolog 1 (Drosophila)	0.010
Dhx58	DEXH (Asp-Glu-X-His) box polypeptide 58	0.010
Ncr1	natural cytotoxicity triggering receptor 1	0.010
Cyth4	cytohesin 4	0.010
Id2	inhibitor of DNA binding 2	0.010
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.010
Cd36	CD36 antigen	0.010
Cd6	CD6 antigen	0.010
Slc2a4	solute carrier family 2 (facilitated glucose transporter), member 4	0.010
Slc15a3	solute carrier family 15, member 3	0.010