Mus musculus

14 known processes

Cxcr5

chemokine (C-X-C motif) receptor 5

(Aliases: MDR15,Blr1,CXCR-5,CXC-R5,Gpcr6)

Cxcr5 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of inflammatory response to antigenic stimulus GO:0002861 21 0.904
Mouse
inflammatory response GO:0006954 244 0.866
Mouse
positive regulation of translational initiation GO:0045948 4 0.851
lymphocyte mediated immunity GO:0002449 139 0.850
t cell migration GO:0072678 19 0.797
Mouse
positive regulation of translational initiation by iron GO:0045994 2 0.795
osteoclast proliferation GO:0002158 4 0.762
positive regulation of adaptive immune response GO:0002821 61 0.742
Mouse
lymph node development GO:0048535 18 0.726
lymphocyte migration GO:0072676 26 0.717
Mouse
positive regulation of chronic inflammatory response GO:0002678 4 0.705
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.704
Mouse
regulation of cell activation GO:0050865 289 0.662
Mouse
positive regulation of cell activation GO:0050867 158 0.652
Mouse
cytokine biosynthetic process GO:0042089 68 0.648
Mouse
lymphocyte differentiation GO:0030098 242 0.627
Mouse
leukocyte activation involved in immune response GO:0002366 126 0.623
Mouse
regulation of t cell activation GO:0050863 170 0.604
Mouse
metal ion homeostasis GO:0055065 189 0.601
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.599
Mouse
cytokine production GO:0001816 319 0.588
Mouse
positive regulation of t cell activation GO:0050870 101 0.588
Mouse
extrinsic apoptotic signaling pathway GO:0097191 126 0.586
Mouse
regulation of leukocyte mediated immunity GO:0002703 104 0.578
Mouse
regulation of adaptive immune response GO:0002819 90 0.571
Mouse
immunoglobulin mediated immune response GO:0016064 69 0.569
b cell mediated immunity GO:0019724 71 0.566
b cell differentiation GO:0030183 78 0.564
regulation of secretion GO:0051046 274 0.559
Mouse
regulation of lymphocyte mediated immunity GO:0002706 84 0.556
cytokine mediated signaling pathway GO:0019221 115 0.554
Mouse
positive regulation of leukocyte proliferation GO:0070665 73 0.553
Mouse
positive regulation of defense response GO:0031349 124 0.535
Mouse
monosaccharide metabolic process GO:0005996 106 0.511
regulation of translational initiation by iron GO:0006447 2 0.504
t cell costimulation GO:0031295 14 0.499
Mouse
inflammatory response to antigenic stimulus GO:0002437 30 0.498
Mouse
synaptic transmission GO:0007268 329 0.493
myeloid cell differentiation GO:0030099 233 0.460
Mouse
dna metabolic process GO:0006259 303 0.460
positive regulation of behavior GO:0048520 40 0.455
Mouse
regulation of corticotropin releasing hormone secretion GO:0043397 2 0.455
regulation of acute inflammatory response GO:0002673 27 0.451
Mouse
regulation of myeloid cell differentiation GO:0045637 96 0.436
necroptotic signaling pathway GO:0097527 3 0.436
interspecies interaction between organisms GO:0044419 83 0.401
jnk cascade GO:0007254 72 0.397
regulation of protein secretion GO:0050708 82 0.393
Mouse
positive regulation of interferon gamma production GO:0032729 39 0.391
Mouse
regulation of immunoglobulin mediated immune response GO:0002889 37 0.387
humoral immune response GO:0006959 57 0.379
Mouse
positive regulation of cell death GO:0010942 224 0.379
regulation of defense response GO:0031347 233 0.379
Mouse
innate immune response GO:0045087 157 0.376
Mouse
regulation of cytokine production GO:0001817 266 0.366
Mouse
negative regulation of multi organism process GO:0043901 68 0.366
regulation of stress activated mapk cascade GO:0032872 69 0.360
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.355
Mouse
adaptive immune response GO:0002250 155 0.348
Mouse
positive regulation of myoblast differentiation GO:0045663 8 0.345
regulation of cytokine secretion GO:0050707 61 0.343
Mouse
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.339
Mouse
positive regulation of jnk cascade GO:0046330 46 0.337
positive regulation of protein kinase b signaling GO:0051897 32 0.334
cellular response to biotic stimulus GO:0071216 92 0.334
cellular response to lipopolysaccharide GO:0071222 77 0.328
negative regulation of growth of symbiont in host GO:0044130 19 0.312
regulation of establishment of protein localization GO:0070201 181 0.309
Mouse
striated muscle tissue development GO:0014706 293 0.303
regulation of lymphocyte activation GO:0051249 240 0.303
Mouse
corticotropin releasing hormone secretion GO:0043396 2 0.301
positive regulation of chronic inflammatory response to antigenic stimulus GO:0002876 2 0.297
regulation of leukocyte proliferation GO:0070663 121 0.295
Mouse
immune effector process GO:0002252 321 0.293
Mouse
defense response to bacterium GO:0042742 119 0.293
gliogenesis GO:0042063 141 0.289
Mouse
protein localization to nucleus GO:0034504 121 0.288
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.286
chemotaxis GO:0006935 247 0.282
Mouse
growth of symbiont in host GO:0044117 23 0.282
myeloid leukocyte differentiation GO:0002573 119 0.282
positive regulation of jun kinase activity GO:0043507 30 0.281
b cell activation involved in immune response GO:0002312 50 0.276
cellular divalent inorganic cation homeostasis GO:0072503 127 0.275
Mouse
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.275
positive regulation of cell development GO:0010720 237 0.273
Mouse
cell chemotaxis GO:0060326 81 0.272
Mouse
positive regulation of intracellular transport GO:0032388 70 0.271
positive regulation of chemotaxis GO:0050921 38 0.265
Mouse
negative regulation of cell proliferation GO:0008285 296 0.262
negative regulation of growth of symbiont involved in interaction with host GO:0044146 19 0.260
glucose transport GO:0015758 56 0.257
positive regulation of protein phosphorylation GO:0001934 242 0.257
positive regulation of peptide hormone secretion GO:0090277 31 0.256
t cell activation GO:0042110 289 0.254
Mouse
regulation of peptidase activity GO:0052547 96 0.254
regulation of response to wounding GO:1903034 189 0.253
Mouse
regulation of cellular response to stress GO:0080135 159 0.250
translational initiation GO:0006413 24 0.250
regulation of translational initiation GO:0006446 15 0.250
positive regulation of inflammatory response to antigenic stimulus GO:0002863 11 0.249
Mouse
i kappab kinase nf kappab signaling GO:0007249 85 0.248
muscle cell differentiation GO:0042692 261 0.245
regulation of b cell proliferation GO:0030888 39 0.242
regulation of protein transport GO:0051223 163 0.241
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.234
Mouse
mapk cascade GO:0000165 281 0.232
protein maturation GO:0051604 176 0.231
positive regulation of monocyte chemotaxis GO:0090026 2 0.229
Mouse
t cell chemotaxis GO:0010818 6 0.228
Mouse
regulation of reactive oxygen species metabolic process GO:2000377 40 0.226
fatty acid transport GO:0015908 28 0.226
regulation of homeostatic process GO:0032844 182 0.224
Mouse
modulation of growth of symbiont involved in interaction with host GO:0044144 19 0.223
dna recombination GO:0006310 92 0.221
acute inflammatory response GO:0002526 41 0.217
Mouse
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.212
response to molecule of bacterial origin GO:0002237 143 0.211
Mouse
regulation of protein serine threonine kinase activity GO:0071900 157 0.210
regulation of jnk cascade GO:0046328 62 0.210
interleukin 12 production GO:0032615 32 0.209
Mouse
prostaglandin transport GO:0015732 7 0.209
organic acid transport GO:0015849 101 0.208
positive regulation of inflammatory response GO:0050729 47 0.208
Mouse
defense response to other organism GO:0098542 197 0.208
cellular chemical homeostasis GO:0055082 215 0.206
Mouse
positive regulation of hair follicle development GO:0051798 6 0.206
response to acid chemical GO:0001101 111 0.205
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.203
positive regulation of cytokine biosynthetic process GO:0042108 40 0.203
Mouse
divalent inorganic cation homeostasis GO:0072507 138 0.203
Mouse
regulation of organic acid transport GO:0032890 16 0.202
leukocyte mediated immunity GO:0002443 174 0.200
Mouse
glucose import GO:0046323 32 0.199
cellular homeostasis GO:0019725 240 0.199
Mouse
response to lipopolysaccharide GO:0032496 128 0.199
Mouse
cellular response to lipid GO:0071396 145 0.198
cellular response to molecule of bacterial origin GO:0071219 83 0.198
regulation of endopeptidase activity GO:0052548 89 0.196
defense response to gram positive bacterium GO:0050830 50 0.192
engulfment of apoptotic cell GO:0043652 3 0.192
lymphocyte chemotaxis GO:0048247 10 0.192
Mouse
apoptotic signaling pathway GO:0097190 306 0.191
Mouse
regulation of b cell activation GO:0050864 81 0.190
cellular response to amino acid stimulus GO:0071230 29 0.188
lymphocyte proliferation GO:0046651 164 0.188
Mouse
positive regulation of osteoclast development GO:2001206 3 0.188
activation of jun kinase activity GO:0007257 15 0.186
regulation of chemotaxis GO:0050920 53 0.185
Mouse
positive regulation of cytokine production GO:0001819 174 0.185
Mouse
immune response activating signal transduction GO:0002757 116 0.183
Mouse
regulation of map kinase activity GO:0043405 120 0.182
positive regulation of immune effector process GO:0002699 107 0.182
Mouse
regulation of hydrolase activity GO:0051336 246 0.180
cytoplasmic transport GO:0016482 234 0.180
Mouse
positive regulation of immunoglobulin mediated immune response GO:0002891 26 0.179
positive regulation of mapk cascade GO:0043410 170 0.176
negative regulation of hydrolase activity GO:0051346 71 0.175
monosaccharide transport GO:0015749 58 0.173
negative regulation of molecular function GO:0044092 258 0.173
b cell activation GO:0042113 161 0.173
anatomical structure homeostasis GO:0060249 145 0.173
peptide transport GO:0015833 133 0.171
positive regulation of lymphocyte activation GO:0051251 140 0.170
Mouse
protein secretion GO:0009306 111 0.169
Mouse
multicellular organismal signaling GO:0035637 91 0.167
positive regulation of map kinase activity GO:0043406 84 0.165
carboxylic acid transport GO:0046942 100 0.164
stress activated mapk cascade GO:0051403 80 0.164
regulation of humoral immune response GO:0002920 22 0.163
Mouse
regulation of cytokine biosynthetic process GO:0042035 59 0.163
Mouse
positive regulation of lymphocyte migration GO:2000403 11 0.163
Mouse
cell fate commitment GO:0045165 210 0.163
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.161
protein localization to organelle GO:0033365 185 0.159
positive regulation of peptide secretion GO:0002793 33 0.157
positive regulation of organic acid transport GO:0032892 11 0.156
protein processing GO:0016485 163 0.156
calcium ion homeostasis GO:0055074 127 0.155
Mouse
muscle tissue development GO:0060537 308 0.155
bone resorption GO:0045453 38 0.155
positive regulation of b cell mediated immunity GO:0002714 26 0.154
integrin activation GO:0033622 8 0.154
chronic inflammatory response to antigenic stimulus GO:0002439 3 0.151
isotype switching GO:0045190 36 0.150
regulation of inflammatory response GO:0050727 147 0.150
Mouse
positive regulation of hormone secretion GO:0046887 38 0.148
syncytium formation GO:0006949 43 0.148
positive regulation of cellular amine metabolic process GO:0033240 5 0.147
branching involved in salivary gland morphogenesis GO:0060445 26 0.147
myeloid leukocyte activation GO:0002274 83 0.146
Mouse
stress activated protein kinase signaling cascade GO:0031098 81 0.144
syncytium formation by plasma membrane fusion GO:0000768 42 0.144
regulation of multi organism process GO:0043900 111 0.144
regulation of intracellular protein transport GO:0033157 82 0.144
alpha beta t cell activation GO:0046631 91 0.143
Mouse
regulation of lymphocyte chemotaxis GO:1901623 6 0.138
Mouse
cellular calcium ion homeostasis GO:0006874 119 0.138
Mouse
protein kinase b signaling GO:0043491 74 0.136
regulation of anion transport GO:0044070 27 0.136
bone remodeling GO:0046849 53 0.135
regulation of membrane potential GO:0042391 192 0.135
immune response regulating signaling pathway GO:0002764 125 0.135
Mouse
temperature homeostasis GO:0001659 26 0.135
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.133
Mouse
growth of symbiont involved in interaction with host GO:0044116 23 0.132
regulation of mapk cascade GO:0043408 248 0.130
cellular response to dna damage stimulus GO:0006974 207 0.130
positive regulation of cytoplasmic transport GO:1903651 40 0.129
negative regulation of defense response GO:0031348 77 0.129
Mouse
dephosphorylation GO:0016311 129 0.128
cellular extravasation GO:0045123 17 0.127
Mouse
negative regulation of glucose transport GO:0010829 9 0.127
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.126
Mouse
positive regulation of acute inflammatory response GO:0002675 16 0.125
Mouse
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.125
positive regulation of apoptotic process GO:0043065 217 0.125
negative regulation of phosphorus metabolic process GO:0010563 184 0.124
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.124
Mouse
single organism cell adhesion GO:0098602 156 0.124
divalent inorganic cation transport GO:0072511 178 0.124
Mouse
regulation of cell motility GO:2000145 236 0.124
Mouse
positive regulation of stress activated mapk cascade GO:0032874 48 0.124
growth involved in symbiotic interaction GO:0044110 23 0.124
regulation of branching involved in salivary gland morphogenesis GO:0060693 11 0.123
regulation of myeloid leukocyte differentiation GO:0002761 58 0.122
positive regulation of lymphocyte proliferation GO:0050671 70 0.122
Mouse
carbohydrate transport GO:0008643 62 0.121
positive regulation of leukocyte mediated immunity GO:0002705 70 0.120
sensory organ morphogenesis GO:0090596 242 0.120
cell recognition GO:0008037 83 0.120
Mouse
myelination GO:0042552 74 0.119
Mouse
regulation of chronic inflammatory response to antigenic stimulus GO:0002874 3 0.118
posttranscriptional regulation of gene expression GO:0010608 155 0.118
positive regulation of ion transport GO:0043270 65 0.115
interleukin 12 biosynthetic process GO:0042090 8 0.114
positive regulation of homeostatic process GO:0032846 64 0.113
regulation of eosinophil degranulation GO:0043309 1 0.113
Mouse
regulation of lymphocyte migration GO:2000401 14 0.113
Mouse
production of molecular mediator of immune response GO:0002440 103 0.113
positive regulation of secretion GO:0051047 130 0.112
leukocyte differentiation GO:0002521 342 0.112
Mouse
establishment of protein localization to organelle GO:0072594 118 0.112
positive regulation of programmed cell death GO:0043068 218 0.112
membrane organization GO:0061024 245 0.111
Mouse
regulation of intracellular transport GO:0032386 159 0.111
anion transport GO:0006820 177 0.110
regulation of glucose transport GO:0010827 32 0.109
protein import GO:0017038 101 0.108
positive regulation of humoral immune response mediated by circulating immunoglobulin GO:0002925 6 0.108
peptide secretion GO:0002790 114 0.108
exocrine system development GO:0035272 45 0.107
regulation of secretion by cell GO:1903530 249 0.107
Mouse
transmission of nerve impulse GO:0019226 76 0.106
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.105
regulation of fever generation by regulation of prostaglandin secretion GO:0071810 2 0.105
somatic diversification of immune receptors GO:0002200 53 0.104
regulation of binding GO:0051098 111 0.104
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.103
Mouse
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 27 0.103
lymphocyte costimulation GO:0031294 15 0.100
Mouse
multicellular organismal homeostasis GO:0048871 164 0.100
ensheathment of neurons GO:0007272 76 0.099
Mouse
nucleotide catabolic process GO:0009166 217 0.099
b cell chemotaxis GO:0035754 3 0.098
regulation of protein kinase activity GO:0045859 232 0.098
positive regulation of t cell migration GO:2000406 10 0.098
Mouse
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 36 0.096
helper t cell chemotaxis GO:0035704 1 0.096
Mouse
skeletal muscle fiber development GO:0048741 58 0.096
regulation of hair follicle development GO:0051797 9 0.095
regulation of humoral immune response mediated by circulating immunoglobulin GO:0002923 10 0.095
leukocyte proliferation GO:0070661 172 0.095
Mouse
cation transport GO:0006812 399 0.095
Mouse
regulation of t cell chemotaxis GO:0010819 5 0.094
Mouse
positive regulation of immunological synapse formation GO:2000522 1 0.093
Mouse
zymogen activation GO:0031638 41 0.093
eosinophil mediated immunity GO:0002447 1 0.093
Mouse
mammary gland epithelial cell proliferation GO:0033598 24 0.092
positive regulation of hydrolase activity GO:0051345 148 0.092
regulation of immunoglobulin production GO:0002637 42 0.091
eosinophil activation GO:0043307 1 0.091
Mouse
positive regulation of icosanoid secretion GO:0032305 7 0.091
positive regulation of protein modification process GO:0031401 299 0.090
interleukin 12 secretion GO:0072610 3 0.090
Mouse
cellular amine metabolic process GO:0044106 44 0.090
t cell selection GO:0045058 34 0.090
Mouse
positive regulation of hair cycle GO:0042635 7 0.089
regulation of fever generation GO:0031620 6 0.089
cellular amino acid metabolic process GO:0006520 103 0.088
lymphocyte activation involved in immune response GO:0002285 93 0.087
gland development GO:0048732 330 0.087
nucleoside triphosphate catabolic process GO:0009143 205 0.087
positive regulation of osteoclast differentiation GO:0045672 15 0.086
negative regulation of alkaline phosphatase activity GO:0010693 3 0.086
endocytosis GO:0006897 168 0.086
chronic inflammatory response GO:0002544 9 0.086
regulation of peptide hormone secretion GO:0090276 75 0.086
negative regulation of osteoblast differentiation GO:0045668 30 0.086
single organismal cell cell adhesion GO:0016337 131 0.085
morphogenesis of a branching structure GO:0001763 203 0.085
Mouse
dendritic cell differentiation GO:0097028 26 0.085
Mouse
t cell extravasation GO:0072683 4 0.085
Mouse
regulation of proteolysis GO:0030162 164 0.084
icosanoid secretion GO:0032309 12 0.084
cytokine metabolic process GO:0042107 71 0.082
Mouse
negative regulation of growth GO:0045926 99 0.082
response to tumor necrosis factor GO:0034612 26 0.081
regulation of protein targeting GO:1903533 61 0.081
regulation of ion homeostasis GO:2000021 64 0.081
Mouse
regulation of interleukin 6 production GO:0032675 55 0.081
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.081
regulation of protein complex assembly GO:0043254 83 0.081
tumor necrosis factor biosynthetic process GO:0042533 10 0.081
Mouse
nuclear transport GO:0051169 139 0.080
positive regulation of fever generation GO:0031622 6 0.080
positive regulation of t cell differentiation GO:0045582 52 0.080
acid secretion GO:0046717 33 0.079
tissue remodeling GO:0048771 102 0.079
humoral immune response mediated by circulating immunoglobulin GO:0002455 14 0.078
positive regulation of cell migration GO:0030335 109 0.078
Mouse
intrinsic apoptotic signaling pathway GO:0097193 132 0.078
regulation of tumor necrosis factor production GO:0032680 49 0.077
Mouse
monocyte extravasation GO:0035696 2 0.077
Mouse
positive regulation of transferase activity GO:0051347 167 0.076
positive regulation of nervous system development GO:0051962 221 0.076
Mouse
protein oligomerization GO:0051259 67 0.075
fever generation GO:0001660 7 0.075
cation homeostasis GO:0055080 212 0.075
Mouse
regulation of prostaglandin secretion GO:0032306 5 0.074
regulation of osteoblast differentiation GO:0045667 67 0.074
single organism nuclear import GO:1902593 95 0.074
hexose transport GO:0008645 56 0.074
regulation of protein import into nucleus GO:0042306 52 0.074
translation GO:0006412 93 0.074
regulation of lymphocyte differentiation GO:0045619 107 0.074
activation of mapk activity GO:0000187 59 0.073
cellular ion homeostasis GO:0006873 165 0.072
Mouse
calcium ion transport into cytosol GO:0060402 48 0.072
Mouse
regulation of myoblast differentiation GO:0045661 29 0.072
negative regulation of phosphate metabolic process GO:0045936 184 0.072
regulation of jun kinase activity GO:0043506 40 0.072
positive regulation of protein import into nucleus GO:0042307 26 0.071
hair follicle development GO:0001942 85 0.071
regulation of fatty acid transport GO:2000191 10 0.071
regulation of hormone levels GO:0010817 211 0.071
protein targeting GO:0006605 143 0.070
activation of cysteine type endopeptidase activity GO:0097202 27 0.070
telencephalon development GO:0021537 186 0.070
Mouse
positive regulation of myeloid leukocyte differentiation GO:0002763 26 0.070
transcription factor import into nucleus GO:0042991 26 0.070
negative regulation of glucose import GO:0046325 7 0.070
regulation of cell migration GO:0030334 219 0.069
Mouse
positive regulation of humoral immune response GO:0002922 11 0.069
Mouse
positive regulation of prostaglandin secretion GO:0032308 5 0.068
exocytosis GO:0006887 121 0.067
Mouse
regulation of protein localization GO:0032880 231 0.067
Mouse
protein import into nucleus GO:0006606 95 0.067
regulation of alpha beta t cell proliferation GO:0046640 18 0.067
Mouse
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.067
regulation of ion transport GO:0043269 215 0.066
regulation of leukocyte differentiation GO:1902105 159 0.066
regulation of cytoplasmic transport GO:1903649 112 0.066
leukocyte migration GO:0050900 124 0.065
Mouse
icosanoid transport GO:0071715 14 0.065
retinal cell programmed cell death GO:0046666 8 0.065
hormone secretion GO:0046879 128 0.064
regulation of epithelial cell proliferation GO:0050678 141 0.063
Mouse
t cell differentiation in thymus GO:0033077 77 0.063
Mouse
membrane invagination GO:0010324 17 0.063
regulation of cellular component biogenesis GO:0044087 181 0.063
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.062
calcium ion transport GO:0006816 159 0.062
Mouse
alpha beta t cell differentiation GO:0046632 69 0.061
mature dendritic cell differentiation GO:0097029 3 0.061
Mouse
positive regulation of dendritic cell chemotaxis GO:2000510 1 0.061
Mouse
carbohydrate metabolic process GO:0005975 230 0.060
regulation of immunological synapse formation GO:2000520 2 0.060
Mouse
regulation of peptide transport GO:0090087 91 0.060
regulation of innate immune response GO:0045088 91 0.060
Mouse
somatic cell dna recombination GO:0016444 51 0.060
regulation of transcription factor import into nucleus GO:0042990 24 0.060
regulation of morphogenesis of a branching structure GO:0060688 53 0.060
amide transport GO:0042886 138 0.059
positive regulation of response to wounding GO:1903036 66 0.059
Mouse
regulation of cysteine type endopeptidase activity GO:2000116 65 0.058
tumor necrosis factor mediated signaling pathway GO:0033209 13 0.058
positive regulation of protein kinase activity GO:0045860 144 0.058
positive regulation of heat generation GO:0031652 7 0.058
cellular metal ion homeostasis GO:0006875 151 0.057
Mouse
muscle cell development GO:0055001 133 0.057
cell activation involved in immune response GO:0002263 126 0.056
Mouse
muscle fiber development GO:0048747 76 0.056
purine containing compound metabolic process GO:0072521 311 0.056
axon ensheathment GO:0008366 76 0.056
Mouse
cell adhesion GO:0007155 329 0.056
positive regulation of protein secretion GO:0050714 52 0.056
activation of immune response GO:0002253 138 0.055
Mouse
myeloid cell activation involved in immune response GO:0002275 34 0.055
Mouse
regulation of translation GO:0006417 71 0.055
negative regulation of ossification GO:0030279 49 0.055
mammary gland alveolus development GO:0060749 22 0.055
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.055
Mouse
regulation of phosphatase activity GO:0010921 12 0.055
epithelial cell proliferation GO:0050673 174 0.055
Mouse
regulation of glucose import GO:0046324 26 0.054
monocarboxylic acid transport GO:0015718 44 0.054
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.054
epithelial tube morphogenesis GO:0060562 303 0.054
Mouse
regulation of cell adhesion mediated by integrin GO:0033628 13 0.054
divalent metal ion transport GO:0070838 172 0.054
Mouse
leukocyte chemotaxis GO:0030595 69 0.053
Mouse
lipid localization GO:0010876 126 0.053
regulation of growth of symbiont in host GO:0044126 19 0.053
positive regulation of peptidase activity GO:0010952 49 0.052
regulation of organ morphogenesis GO:2000027 144 0.052
hexose metabolic process GO:0019318 98 0.052
response to organic cyclic compound GO:0014070 198 0.052
osteoclast differentiation GO:0030316 62 0.052
positive regulation of interleukin 12 production GO:0032735 21 0.052
Mouse
skeletal muscle organ development GO:0060538 163 0.052
carbohydrate derivative catabolic process GO:1901136 231 0.051
aromatic compound catabolic process GO:0019439 286 0.051
fatty acid derivative transport GO:1901571 14 0.051
microglial cell activation involved in immune response GO:0002282 1 0.051
Mouse
neuron projection guidance GO:0097485 141 0.051
Mouse
neuromuscular synaptic transmission GO:0007274 16 0.051
thymic t cell selection GO:0045061 22 0.050
Mouse
programmed necrotic cell death GO:0097300 28 0.050
ossification GO:0001503 216 0.050
regulation of tumor necrosis factor biosynthetic process GO:0042534 10 0.049
Mouse
positive regulation of protein transport GO:0051222 93 0.049
pigment metabolic process GO:0042440 32 0.049
positive regulation of cellular component biogenesis GO:0044089 94 0.048
positive regulation of protein localization to nucleus GO:1900182 30 0.048
cellular response to hormone stimulus GO:0032870 150 0.048
positive regulation of cell motility GO:2000147 116 0.048
Mouse
phagocytosis GO:0006909 66 0.048
ribonucleoside metabolic process GO:0009119 245 0.048
regulation of protein localization to nucleus GO:1900180 60 0.047
rap protein signal transduction GO:0032486 3 0.047
action potential GO:0001508 78 0.047
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.046
organic cyclic compound catabolic process GO:1901361 295 0.046
defense response to gram negative bacterium GO:0050829 28 0.046
peptide hormone secretion GO:0030072 109 0.046
regulation of endothelial cell chemotaxis GO:2001026 1 0.046
response to growth factor GO:0070848 198 0.046
cellular response to acid chemical GO:0071229 68 0.046
organic anion transport GO:0015711 137 0.045
morphogenesis of a branching epithelium GO:0061138 193 0.045
Mouse
regulation of immune complex clearance by monocytes and macrophages GO:0090264 2 0.045
Mouse
eosinophil degranulation GO:0043308 1 0.045
Mouse
negative regulation of muscle cell differentiation GO:0051148 33 0.045
reactive oxygen species metabolic process GO:0072593 84 0.045
regulation of b cell mediated immunity GO:0002712 37 0.044
regulation of t cell extravasation GO:2000407 3 0.044
Mouse
regulation of epidermis development GO:0045682 33 0.044
positive regulation of corticotropin releasing hormone secretion GO:0051466 1 0.044
glucose metabolic process GO:0006006 92 0.044
interleukin 10 secretion GO:0072608 4 0.044
extracellular structure organization GO:0043062 148 0.044
positive regulation of antigen receptor mediated signaling pathway GO:0050857 9 0.044
Mouse
regulation of cellular response to growth factor stimulus GO:0090287 82 0.044
regulation of interleukin 1 production GO:0032652 26 0.044
Mouse
regulation of icosanoid secretion GO:0032303 8 0.044
salivary gland development GO:0007431 37 0.043
regulation of monocyte extravasation GO:2000437 2 0.043
Mouse
maintenance of location GO:0051235 89 0.043
Mouse
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.043
Mouse
negative regulation of phosphatase activity GO:0010923 5 0.043
positive regulation of proteolysis GO:0045862 85 0.043
regulation of syncytium formation by plasma membrane fusion GO:0060142 23 0.043
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.043
ribose phosphate metabolic process GO:0019693 291 0.042
cerebral cortex development GO:0021987 86 0.042
Mouse
regulation of t cell proliferation GO:0042129 92 0.042
Mouse
negative regulation of immune effector process GO:0002698 55 0.042
Mouse
regulation of osteoclast differentiation GO:0045670 36 0.041
acute phase response GO:0006953 10 0.041
interferon gamma production GO:0032609 67 0.041
Mouse
positive regulation of innate immune response GO:0045089 80 0.041
axonogenesis GO:0007409 274 0.041
Mouse
guanosine containing compound metabolic process GO:1901068 144 0.041
nucleoside triphosphate metabolic process GO:0009141 230 0.041
positive regulation of endopeptidase activity GO:0010950 43 0.041
regulation of mast cell activation involved in immune response GO:0033006 17 0.041
purine ribonucleotide catabolic process GO:0009154 208 0.040
organelle assembly GO:0070925 177 0.040
neuronal action potential GO:0019228 54 0.040
purine nucleoside metabolic process GO:0042278 241 0.040
mammary gland lobule development GO:0061377 22 0.039
regulation of cell adhesion GO:0030155 154 0.039
intracellular protein transport GO:0006886 204 0.039
t cell differentiation involved in immune response GO:0002292 30 0.039
striated muscle cell development GO:0055002 125 0.039
myeloid dendritic cell chemotaxis GO:0002408 2 0.039

Cxcr5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.046
musculoskeletal system disease DOID:17 0 0.046