|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.858
|
Human |
|
|
signal transduction involved in mitotic dna damage checkpoint
|
GO:1902402 |
3 |
0.680
|
|
|
|
signal transduction involved in dna damage checkpoint
|
GO:0072422 |
3 |
0.612
|
|
|
|
signal transduction involved in cell cycle checkpoint
|
GO:0072395 |
3 |
0.594
|
|
|
|
negative regulation of nik nf kappab signaling
|
GO:1901223 |
2 |
0.594
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.573
|
|
|
|
negative regulation of cell cycle arrest
|
GO:0071157 |
1 |
0.555
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.548
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.522
|
|
|
|
mitotic g1 dna damage checkpoint
|
GO:0031571 |
4 |
0.516
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.482
|
|
|
|
cell cycle arrest
|
GO:0007050 |
37 |
0.455
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.434
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.401
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.398
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.395
|
|
|
|
epidermal growth factor receptor signaling pathway via i kappab kinase nf kappab cascade
|
GO:0038168 |
1 |
0.388
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.386
|
|
|
|
regulation of protein stability
|
GO:0031647 |
52 |
0.378
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.375
|
Human |
|
|
negative regulation of dna replication
|
GO:0008156 |
4 |
0.362
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
51 |
0.353
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
53 |
0.322
|
|
|
|
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest
|
GO:0006977 |
3 |
0.321
|
|
|
|
signal transduction involved in dna integrity checkpoint
|
GO:0072401 |
3 |
0.314
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.299
|
Human |
|
|
negative regulation of cell cycle process
|
GO:0010948 |
69 |
0.299
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.283
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.278
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.270
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.264
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.253
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.240
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.229
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.222
|
|
|
|
signal transduction involved in mitotic cell cycle checkpoint
|
GO:0072413 |
3 |
0.219
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.216
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.216
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.215
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.209
|
|
|
|
regulation of cell cycle arrest
|
GO:0071156 |
12 |
0.206
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.201
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.201
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
35 |
0.197
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.191
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.190
|
|
|
|
regulation of protein deacetylation
|
GO:0090311 |
17 |
0.188
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.182
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.181
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.180
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.177
|
Human |
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.175
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.173
|
|
|
|
signal transduction involved in mitotic dna integrity checkpoint
|
GO:1902403 |
3 |
0.172
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.171
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.170
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
57 |
0.166
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.166
|
|
|
|
positive regulation of binding
|
GO:0051099 |
49 |
0.161
|
|
|
|
cellular response to interleukin 4
|
GO:0071353 |
21 |
0.161
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.160
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
47 |
0.158
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.157
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.157
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.151
|
|
|
|
dna repair
|
GO:0006281 |
107 |
0.146
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.146
|
|
|
|
dna replication
|
GO:0006260 |
52 |
0.140
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.135
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.133
|
|
|
|
cell aging
|
GO:0007569 |
35 |
0.131
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.129
|
|
|
|
viral life cycle
|
GO:0019058 |
36 |
0.127
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.126
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
34 |
0.125
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.125
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
26 |
0.124
|
|
|
|
protein deacetylation
|
GO:0006476 |
32 |
0.121
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.120
|
|
|
|
positive regulation of apoptotic process involved in morphogenesis
|
GO:1902339 |
4 |
0.117
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.115
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.115
|
Human |
|
|
circadian regulation of gene expression
|
GO:0032922 |
48 |
0.114
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.113
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.112
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.111
|
Human |
|
|
nik nf kappab signaling
|
GO:0038061 |
14 |
0.111
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
35 |
0.109
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.108
|
|
|
|
positive regulation of apoptotic process involved in mammary gland involution
|
GO:0060058 |
4 |
0.108
|
|
|
|
intracellular signal transduction involved in g1 dna damage checkpoint
|
GO:1902400 |
3 |
0.107
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.106
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.103
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.103
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.103
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.102
|
Human |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.102
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
34 |
0.098
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.097
|
|
|
|
signal transduction involved in mitotic g1 dna damage checkpoint
|
GO:0072431 |
3 |
0.096
|
|
|
|
positive regulation of histone modification
|
GO:0031058 |
28 |
0.096
|
|
|
|
regulation of histone modification
|
GO:0031056 |
56 |
0.096
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.094
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.094
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.092
|
|
|
|
macromolecule deacylation
|
GO:0098732 |
37 |
0.091
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.091
|
|
|
|
apoptotic process involved in mammary gland involution
|
GO:0060057 |
4 |
0.091
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
52 |
0.090
|
|
|
|
response to hypoxia
|
GO:0001666 |
58 |
0.090
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.088
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.087
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.086
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
79 |
0.085
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.085
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
42 |
0.083
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.082
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.082
|
|
|
|
positive regulation of mammary gland involution
|
GO:1903521 |
4 |
0.081
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.081
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902043 |
13 |
0.081
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.081
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.081
|
|
|
|
response to uv
|
GO:0009411 |
44 |
0.081
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
36 |
0.081
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.080
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
35 |
0.080
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.080
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
19 |
0.080
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.079
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.079
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.078
|
|
|
|
viral process
|
GO:0016032 |
41 |
0.077
|
|
|
|
endoplasmic reticulum calcium ion homeostasis
|
GO:0032469 |
11 |
0.076
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.076
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.075
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.073
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.073
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.073
|
|
|
|
negative regulation of chromosome organization
|
GO:2001251 |
30 |
0.072
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.072
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.071
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.071
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.071
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.070
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
58 |
0.070
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.069
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.068
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.068
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.067
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
48 |
0.067
|
|
|
|
double strand break repair
|
GO:0006302 |
48 |
0.066
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.066
|
Human |
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.065
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.065
|
|
|
|
epidermal growth factor receptor signaling pathway via positive regulation of nf kappab transcription factor activity
|
GO:0038167 |
1 |
0.065
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
49 |
0.065
|
|
|
|
telomere maintenance via telomerase
|
GO:0007004 |
1 |
0.064
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.064
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.064
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.063
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
61 |
0.063
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.063
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.063
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.063
|
|
|
|
negative regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903051 |
22 |
0.063
|
|
|
|
negative regulation of vasculature development
|
GO:1901343 |
26 |
0.063
|
|
|
|
negative regulation of viral process
|
GO:0048525 |
23 |
0.062
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.062
|
|
|
|
histone deacetylation
|
GO:0016575 |
26 |
0.061
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.061
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.060
|
Human |
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.060
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
57 |
0.060
|
|
|
|
blastocyst development
|
GO:0001824 |
80 |
0.059
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.059
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.059
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.059
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.058
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.058
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.058
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.058
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.058
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
30 |
0.057
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.057
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.056
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.056
|
|
|
|
mammary gland involution
|
GO:0060056 |
9 |
0.056
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.055
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
28 |
0.053
|
|
|
|
response to interleukin 4
|
GO:0070670 |
23 |
0.053
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.053
|
|
|
|
regulation of transcription during meiosis
|
GO:0051037 |
1 |
0.053
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
47 |
0.052
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.052
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.052
|
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
25 |
0.051
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.051
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
56 |
0.050
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.050
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.050
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.049
|
Human |
|
|
angiogenesis
|
GO:0001525 |
201 |
0.049
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
61 |
0.047
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.047
|
|
|
|
regulation of histone deacetylation
|
GO:0031063 |
12 |
0.047
|
|
|
|
positive regulation of chromatin modification
|
GO:1903310 |
28 |
0.047
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.047
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
45 |
0.047
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.047
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.046
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
36 |
0.046
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.046
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.045
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.045
|
|
|
|
dna biosynthetic process
|
GO:0071897 |
22 |
0.045
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.045
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.045
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.044
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.044
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.044
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.044
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.044
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.044
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.044
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.043
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.043
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.043
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.043
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.043
|
Human |
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.043
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
27 |
0.043
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.042
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.042
|
|
|
|
positive regulation of chromosome organization
|
GO:2001252 |
33 |
0.042
|
|
|
|
nucleus organization
|
GO:0006997 |
45 |
0.042
|
|
|
|
protein deacylation
|
GO:0035601 |
36 |
0.041
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.041
|
|
|
|
protein stabilization
|
GO:0050821 |
25 |
0.041
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.041
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.041
|
|
|
|
male meiosis i
|
GO:0007141 |
16 |
0.041
|
|
|
|
histone h3 acetylation
|
GO:0043966 |
14 |
0.040
|
|
|
|
regulation of defense response to virus by host
|
GO:0050691 |
8 |
0.040
|
|
|
|
negative regulation of cellular protein catabolic process
|
GO:1903363 |
22 |
0.040
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
39 |
0.040
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.039
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.038
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.038
|
|
|
|
response to retinoic acid
|
GO:0032526 |
56 |
0.038
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.038
|
|
|
|
rna dependent dna replication
|
GO:0006278 |
3 |
0.038
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.038
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
31 |
0.037
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.037
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.037
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.037
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.037
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.037
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.037
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.037
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.036
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.036
|
|
|
|
mammary gland morphogenesis
|
GO:0060443 |
54 |
0.036
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.036
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.036
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.036
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.036
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
21 |
0.035
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
27 |
0.035
|
|
|
|
maintenance of protein location in nucleus
|
GO:0051457 |
2 |
0.035
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.035
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.035
|
|
|
|
neuroblast differentiation
|
GO:0014016 |
2 |
0.035
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.035
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.034
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.034
|
|
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
19 |
0.034
|
|
|
|
response to gamma radiation
|
GO:0010332 |
22 |
0.034
|
|
|
|
notch signaling pathway
|
GO:0007219 |
71 |
0.034
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
52 |
0.034
|
Human |
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.034
|
|
|
|
telomere maintenance
|
GO:0000723 |
19 |
0.033
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.033
|
|
|
|
cellular senescence
|
GO:0090398 |
11 |
0.033
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.033
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.033
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.032
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.032
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.032
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.032
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.032
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
42 |
0.031
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
27 |
0.031
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.031
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.031
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.031
|
|
|
|
negative regulation of blood vessel morphogenesis
|
GO:2000181 |
25 |
0.031
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.030
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
38 |
0.030
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.030
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
44 |
0.030
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
57 |
0.030
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.029
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.029
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.029
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.029
|
|
|
|
regulation of defense response to virus
|
GO:0050688 |
18 |
0.028
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.028
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
43 |
0.027
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.027
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.027
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.027
|
|
|
|
negative regulation of dna damage response signal transduction by p53 class mediator
|
GO:0043518 |
5 |
0.027
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.027
|
|
|
|
cellular response to gamma radiation
|
GO:0071480 |
4 |
0.027
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.027
|
|
|
|
skeletal muscle cell differentiation
|
GO:0035914 |
66 |
0.027
|
|
|
|
rna processing
|
GO:0006396 |
105 |
0.027
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.027
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.026
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.026
|
|
|
|
zymogen activation
|
GO:0031638 |
41 |
0.026
|
|
|
|
positive regulation of protein binding
|
GO:0032092 |
29 |
0.026
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.026
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.026
|
|
|
|
mrna metabolic process
|
GO:0016071 |
84 |
0.026
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.025
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.025
|
|
|
|
regulation of dna replication
|
GO:0006275 |
17 |
0.025
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.025
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.025
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.025
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.025
|
|
|
|
regulation of telomerase activity
|
GO:0051972 |
1 |
0.025
|
|
|
|
regulation of type i interferon mediated signaling pathway
|
GO:0060338 |
7 |
0.025
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.025
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.025
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.025
|
|
|
|
protein acylation
|
GO:0043543 |
64 |
0.024
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.024
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.024
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.024
|
|
|
|
negative regulation of angiogenesis
|
GO:0016525 |
25 |
0.024
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.024
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.024
|
|
|
|
regulation of dna binding
|
GO:0051101 |
39 |
0.024
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.024
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.024
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.023
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
62 |
0.023
|
|
|
|
chromatin assembly
|
GO:0031497 |
13 |
0.023
|
|
|
|
nuclear export
|
GO:0051168 |
34 |
0.023
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.023
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.023
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.023
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.022
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.022
|
|
|
|
positive regulation of antimicrobial peptide biosynthetic process
|
GO:0002807 |
1 |
0.022
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.022
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.022
|
|
|
|
cellular response to nitric oxide
|
GO:0071732 |
4 |
0.022
|
|
|
|
regulation of translation
|
GO:0006417 |
71 |
0.022
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.022
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.022
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.022
|
Human |
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
34 |
0.021
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.021
|
|
|
|
t helper 17 cell lineage commitment
|
GO:0072540 |
4 |
0.021
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.021
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.021
|
|
|
|
regulation of tissue remodeling
|
GO:0034103 |
38 |
0.021
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.021
|
|
|
|
positive regulation of transcription elongation from rna polymerase ii promoter
|
GO:0032968 |
2 |
0.021
|
|
|
|
dna packaging
|
GO:0006323 |
30 |
0.021
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.021
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.021
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.021
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.021
|
|
|
|
chromatin silencing at rdna
|
GO:0000183 |
3 |
0.021
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.021
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
73 |
0.020
|
|
|
|
retrograde transport endosome to golgi
|
GO:0042147 |
2 |
0.020
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.020
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.020
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.020
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.020
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.020
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.020
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
33 |
0.020
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.020
|
|
|
|
protein methylation
|
GO:0006479 |
81 |
0.020
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.020
|
|
|
|
fibroblast proliferation
|
GO:0048144 |
35 |
0.020
|
|
|
|
segmentation
|
GO:0035282 |
93 |
0.020
|
|
|
|
modification by symbiont of host morphology or physiology
|
GO:0044003 |
4 |
0.020
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.019
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.019
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.019
|
|
|
|
regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:2000058 |
14 |
0.019
|
|
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.019
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.019
|
|
|
|
viral gene expression
|
GO:0019080 |
3 |
0.019
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
42 |
0.019
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.019
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.019
|
|
|
|
response to interferon gamma
|
GO:0034341 |
34 |
0.019
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.019
|
|
|
|
retinoic acid receptor signaling pathway
|
GO:0048384 |
17 |
0.019
|
|
|
|
protein alkylation
|
GO:0008213 |
81 |
0.019
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
46 |
0.019
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.019
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.019
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
31 |
0.019
|
|
|
|
apoptotic process involved in morphogenesis
|
GO:0060561 |
25 |
0.019
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.018
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.018
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.018
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.018
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.018
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.018
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.018
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.018
|
|
|
|
maintenance of protein localization in organelle
|
GO:0072595 |
2 |
0.018
|
|
|
|
male meiosis
|
GO:0007140 |
37 |
0.018
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.018
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.018
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.018
|
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.018
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.017
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.017
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.017
|
|
|
|
positive regulation of antimicrobial humoral response
|
GO:0002760 |
2 |
0.017
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.017
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.017
|
|
|
|
response to type i interferon
|
GO:0034340 |
12 |
0.017
|
|
|
|
positive regulation of defense response to virus by host
|
GO:0002230 |
6 |
0.017
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.017
|
|
|
|
meiosis i
|
GO:0007127 |
60 |
0.017
|
|
|
|
mrna processing
|
GO:0006397 |
63 |
0.017
|
|
|
|
nucleic acid phosphodiester bond hydrolysis
|
GO:0090305 |
49 |
0.017
|
|
|
|
rna splicing via transesterification reactions with bulged adenosine as nucleophile
|
GO:0000377 |
43 |
0.017
|
|
|
|
regulation of circadian rhythm
|
GO:0042752 |
58 |
0.017
|
|
|
|
regulation of chromatin silencing
|
GO:0031935 |
2 |
0.017
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.016
|
|
|
|
cellular response to type i interferon
|
GO:0071357 |
10 |
0.016
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.016
|
|
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.016
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
40 |
0.016
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.016
|
|
|
|
cell death in response to oxidative stress
|
GO:0036473 |
24 |
0.016
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.016
|
|
|
|
regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902041 |
22 |
0.016
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.016
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
26 |
0.016
|
|
|
|
regulation of antimicrobial peptide production
|
GO:0002784 |
1 |
0.016
|
|
|
|
sensory system development
|
GO:0048880 |
3 |
0.016
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.016
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.016
|
|
|
|
mitochondrial transport
|
GO:0006839 |
36 |
0.016
|
|
|
|
positive regulation of cell cycle phase transition
|
GO:1901989 |
17 |
0.015
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.015
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.015
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.015
|
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
23 |
0.015
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.015
|
|
|
|
myosin filament organization
|
GO:0031033 |
3 |
0.015
|
|
|
|
regulation of toll signaling pathway
|
GO:0008592 |
1 |
0.015
|
|
|
|
positive regulation of antimicrobial peptide production
|
GO:0002225 |
1 |
0.015
|
|
|
|
negative regulation of organ growth
|
GO:0046621 |
17 |
0.015
|
|
|
|
response to x ray
|
GO:0010165 |
11 |
0.015
|
|
|
|
regulation of mitochondrial membrane permeability
|
GO:0046902 |
17 |
0.015
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.015
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.015
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
18 |
0.015
|
|
|
|
rna splicing
|
GO:0008380 |
54 |
0.015
|
|
|
|
zygotic determination of anterior posterior axis embryo
|
GO:0007354 |
3 |
0.015
|
|
|
|
negative regulation of innate immune response
|
GO:0045824 |
17 |
0.015
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.015
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.015
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.015
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
51 |
0.015
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.015
|
|
|
|
protein homotrimerization
|
GO:0070207 |
4 |
0.014
|
|
|
|
response to antibiotic
|
GO:0046677 |
11 |
0.014
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.014
|
|
