Mus musculus

187 known processes

Dlx2

distal-less homeobox 2

(Aliases: Dlx-2,AW121999,Tes-1)

Dlx2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
embryonic skeletal system development GO:0048706 120 0.990
cerebral cortex gabaergic interneuron fate commitment GO:0021893 2 0.988
cerebral cortex gabaergic interneuron differentiation GO:0021892 9 0.980
auditory receptor cell fate determination GO:0042668 3 0.979
cerebral cortex neuron differentiation GO:0021895 19 0.973
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.956
telencephalon development GO:0021537 186 0.948
embryonic organ morphogenesis GO:0048562 276 0.939
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.934
regionalization GO:0003002 337 0.921
embryonic skeletal system morphogenesis GO:0048704 91 0.916
embryonic heart tube formation GO:0003144 1 0.903
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.900
central nervous system neuron differentiation GO:0021953 162 0.899
pancreatic pp cell fate commitment GO:0003329 2 0.890
forebrain generation of neurons GO:0021872 63 0.889
olfactory nerve development GO:0021553 3 0.887
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.866
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.860
neural crest cell migration involved in autonomic nervous system development GO:1901166 5 0.860
regulation of glial cell differentiation GO:0045685 41 0.847
positive regulation of epithelial cell proliferation GO:0050679 68 0.838
Mouse
commitment of multipotent stem cells to neuronal lineage in forebrain GO:0021898 3 0.836
response to testosterone GO:0033574 3 0.835
somitogenesis GO:0001756 69 0.827
epithelial tube morphogenesis GO:0060562 303 0.816
forebrain neuron differentiation GO:0021879 52 0.806
palate development GO:0060021 76 0.799
Mouse
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.789
stem cell development GO:0048864 219 0.784
ear development GO:0043583 200 0.784
Mouse
subpallium development GO:0021544 20 0.768
stem cell differentiation GO:0048863 268 0.766
ear morphogenesis GO:0042471 118 0.764
Mouse
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.761
skeletal system morphogenesis GO:0048705 203 0.761
regulation of auditory receptor cell differentiation GO:0045607 4 0.760
limb morphogenesis GO:0035108 149 0.742
Mouse
cardiac chamber morphogenesis GO:0003206 93 0.730
regulation of gliogenesis GO:0014013 50 0.726
pallium development GO:0021543 120 0.713
olfactory lobe development GO:0021988 32 0.709
regulation of transcription from rna polymerase ii promoter involved in forebrain neuron fate commitment GO:0021882 3 0.706
epithelial cell development GO:0002064 159 0.700
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.697
odontogenesis GO:0042476 78 0.691
renal system development GO:0072001 225 0.690
skeletal system development GO:0001501 356 0.689
notch signaling pathway GO:0007219 71 0.661
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.657
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.656
appendage development GO:0048736 166 0.643
Mouse
appendage morphogenesis GO:0035107 149 0.638
Mouse
hippocampus development GO:0021766 52 0.634
cell proliferation involved in heart valve development GO:2000793 2 0.632
neuron fate specification GO:0048665 30 0.625
urogenital system development GO:0001655 261 0.620
brain segmentation GO:0035284 3 0.611
salivary gland morphogenesis GO:0007435 33 0.607
astrocyte fate commitment GO:0060018 4 0.599
gliogenesis GO:0042063 141 0.599
forebrain neuron fate commitment GO:0021877 13 0.596
cranial nerve development GO:0021545 41 0.594
cellular amino acid metabolic process GO:0006520 103 0.589
endocardial cushion to mesenchymal transition GO:0090500 5 0.579
mitral valve development GO:0003174 4 0.575
gabaergic neuron differentiation GO:0097154 11 0.575
segmentation GO:0035282 93 0.571
cartilage morphogenesis GO:0060536 11 0.569
hemangioblast cell differentiation GO:0060217 1 0.565
forebrain neuron development GO:0021884 30 0.564
respiratory system development GO:0060541 190 0.562
Mouse
negative regulation of gliogenesis GO:0014014 23 0.560
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.553
middle ear morphogenesis GO:0042474 23 0.550
cardiac ventricle morphogenesis GO:0003208 50 0.542
cardiac right ventricle formation GO:0003219 3 0.542
limb development GO:0060173 166 0.542
Mouse
morphogenesis of a branching epithelium GO:0061138 193 0.535
inner ear receptor cell differentiation GO:0060113 61 0.533
regulation of mast cell differentiation GO:0060375 3 0.531
regulation of wnt signaling pathway GO:0030111 123 0.518
Mouse
semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:0071527 1 0.513
mesenchyme development GO:0060485 152 0.513
hindbrain development GO:0030902 128 0.512
autonomic nervous system development GO:0048483 43 0.508
neural tube closure GO:0001843 90 0.508
circadian rhythm GO:0007623 114 0.507
oligodendrocyte differentiation GO:0048709 53 0.497
regulation of histone modification GO:0031056 56 0.496
cell differentiation in spinal cord GO:0021515 53 0.490
subpallium neuron fate commitment GO:0060163 2 0.486
negative regulation of cell development GO:0010721 169 0.484
regulation of stem cell differentiation GO:2000736 50 0.475
cell fate specification GO:0001708 72 0.475
negative regulation of neuron differentiation GO:0045665 101 0.472
globus pallidus development GO:0021759 2 0.461
hair cell differentiation GO:0035315 40 0.461
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.450
cell fate commitment GO:0045165 210 0.449
specification of organ identity GO:0010092 30 0.447
central nervous system segmentation GO:0035283 3 0.447
regulation of oligodendrocyte differentiation GO:0048713 23 0.444
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.443
transdifferentiation GO:0060290 1 0.443
odontogenesis of dentin containing tooth GO:0042475 66 0.440
rhombomere 3 morphogenesis GO:0021658 2 0.437
cerebral cortex gabaergic interneuron migration GO:0021853 6 0.436
metanephric capsule specification GO:0072267 1 0.434
embryonic limb morphogenesis GO:0030326 126 0.428
Mouse
regulation of retina development in camera type eye GO:1902866 3 0.428
negative regulation of nervous system development GO:0051961 156 0.426
primary neural tube formation GO:0014020 95 0.425
regulation of stem cell maintenance GO:2000036 17 0.424
pancreatic pp cell differentiation GO:0003312 2 0.417
cell proliferation in hindbrain GO:0021534 10 0.413
forebrain development GO:0030900 302 0.412
skeletal muscle cell differentiation GO:0035914 66 0.410
pharyngeal system development GO:0060037 17 0.408
ectoderm formation GO:0001705 3 0.407
limbic system development GO:0021761 72 0.403
trophectodermal cell differentiation GO:0001829 21 0.402
sinoatrial node cell differentiation GO:0060921 3 0.396
apoptotic process involved in outflow tract morphogenesis GO:0003275 2 0.396
branching morphogenesis of an epithelial tube GO:0048754 159 0.387
chromatin modification GO:0016568 187 0.387
stem cell maintenance GO:0019827 130 0.383
negative regulation of glial cell differentiation GO:0045686 21 0.383
histone acetylation GO:0016573 41 0.374
neuron migration GO:0001764 122 0.361
kidney development GO:0001822 213 0.356
mesonephros development GO:0001823 97 0.355
glial cell differentiation GO:0010001 131 0.354
tendon formation GO:0035992 4 0.352
skeletal muscle organ development GO:0060538 163 0.349
regulation of neuron projection development GO:0010975 169 0.347
chromatin organization GO:0006325 206 0.342
lymphocyte differentiation GO:0030098 242 0.341
somite development GO:0061053 81 0.339
regulation of astrocyte differentiation GO:0048710 20 0.338
regulation of cellular amino acid metabolic process GO:0006521 5 0.337
mesenchymal cell differentiation GO:0048762 107 0.335
cellular ketone metabolic process GO:0042180 84 0.334
branching involved in ureteric bud morphogenesis GO:0001658 56 0.332
erythrocyte maturation GO:0043249 6 0.329
epidermis development GO:0008544 187 0.327
rhombomere 3 development GO:0021569 4 0.326
inner ear morphogenesis GO:0042472 101 0.324
Mouse
chondrocyte differentiation GO:0002062 72 0.319
outflow tract morphogenesis GO:0003151 53 0.318
positive regulation of keratinocyte proliferation GO:0010838 4 0.312
amine metabolic process GO:0009308 45 0.310
prostate gland morphogenesis GO:0060512 32 0.310
positive regulation of cellular amine metabolic process GO:0033240 5 0.307
epithelial cell fate commitment GO:0072148 13 0.307
pancreatic a cell fate commitment GO:0003326 2 0.303
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.302
locomotory behavior GO:0007626 195 0.294
dorsal aorta development GO:0035907 6 0.293
negative regulation of insulin like growth factor receptor signaling pathway GO:0043569 5 0.292
positive regulation of neuron differentiation GO:0045666 141 0.290
cell maturation GO:0048469 127 0.286
apoptotic signaling pathway GO:0097190 306 0.286
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.283
hindbrain tangential cell migration GO:0021934 2 0.283
embryonic nail plate morphogenesis GO:0035880 3 0.283
regulation of ossification GO:0030278 112 0.282
negative regulation of apoptotic process involved in outflow tract morphogenesis GO:1902257 2 0.280
dentate gyrus development GO:0021542 14 0.278
regulation of epidermal cell differentiation GO:0045604 21 0.277
regulation of neuron apoptotic process GO:0043523 122 0.274
embryonic viscerocranium morphogenesis GO:0048703 8 0.273
regulation of cellular ketone metabolic process GO:0010565 66 0.272
neural precursor cell proliferation GO:0061351 121 0.271
regulation of epithelial cell proliferation GO:0050678 141 0.270
Mouse
paraxial mesodermal cell fate commitment GO:0048343 2 0.267
regulation of canonical wnt signaling pathway GO:0060828 82 0.267
Mouse
histone modification GO:0016570 159 0.265
mechanoreceptor differentiation GO:0042490 67 0.264
mesonephric tubule morphogenesis GO:0072171 63 0.264
cardiac chamber development GO:0003205 108 0.261
mesenchymal cell development GO:0014031 93 0.260
cell differentiation in hindbrain GO:0021533 24 0.258
canonical wnt signaling pathway GO:0060070 130 0.258
Mouse
cell type specific apoptotic process GO:0097285 268 0.257
locus ceruleus development GO:0021703 1 0.257
nephron morphogenesis GO:0072028 69 0.255
pyramidal neuron migration GO:0021852 1 0.249
cardiac ventricle development GO:0003231 83 0.248
his purkinje system cell differentiation GO:0060932 2 0.247
renal tubule development GO:0061326 87 0.247
negative regulation of synapse maturation GO:2000297 2 0.246
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.244
wnt signaling pathway GO:0016055 188 0.240
Mouse
sensory organ morphogenesis GO:0090596 242 0.239
Mouse
dopaminergic neuron differentiation GO:0071542 14 0.235
olfactory bulb interneuron development GO:0021891 7 0.231
regulation of cellular amine metabolic process GO:0033238 20 0.228
epithelial cell proliferation GO:0050673 174 0.227
Mouse
mesenchymal to epithelial transition GO:0060231 12 0.226
regulation of heart morphogenesis GO:2000826 22 0.225
retinal bipolar neuron differentiation GO:0060040 5 0.225
protein kinase b signaling GO:0043491 74 0.225
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.224
regulation of organ morphogenesis GO:2000027 144 0.222
peptidyl lysine modification GO:0018205 77 0.221
cardiac epithelial to mesenchymal transition GO:0060317 18 0.221
regulation of oxidative phosphorylation uncoupler activity GO:2000275 3 0.221
embryonic forelimb morphogenesis GO:0035115 32 0.219
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:2000764 1 0.218
diencephalon development GO:0021536 63 0.218
chemotaxis GO:0006935 247 0.217
Mouse
otic placode formation GO:0043049 1 0.214
sensory perception GO:0007600 245 0.213
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 0.213
epithelial cell proliferation involved in salivary gland morphogenesis GO:0060664 7 0.212
peripheral nervous system neuron development GO:0048935 9 0.205
facial nerve morphogenesis GO:0021610 11 0.202
forebrain regionalization GO:0021871 25 0.201
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.199
cardiac muscle tissue development GO:0048738 130 0.199
ventral spinal cord interneuron differentiation GO:0021514 16 0.198
branching involved in prostate gland morphogenesis GO:0060442 15 0.197
rhombomere 2 development GO:0021568 2 0.197
negative regulation of peroxisome proliferator activated receptor signaling pathway GO:0035359 3 0.195
regulation of epidermis development GO:0045682 33 0.195
regulation of stem cell proliferation GO:0072091 78 0.194
neuron projection extension GO:1990138 64 0.194
tube formation GO:0035148 140 0.191
regulation of skeletal muscle cell differentiation GO:2001014 11 0.189
mitral valve morphogenesis GO:0003183 4 0.188
auditory receptor cell fate specification GO:0042667 1 0.188
regulation of transcription involved in cell fate commitment GO:0060850 15 0.187
placenta development GO:0001890 140 0.187
Mouse
peripheral nervous system neuron axonogenesis GO:0048936 3 0.187
intracellular distribution of mitochondria GO:0048312 1 0.187
regulation of system process GO:0044057 200 0.185
cerebellar granule cell precursor proliferation GO:0021930 10 0.184
epithelial cell morphogenesis GO:0003382 41 0.181
nephron tubule morphogenesis GO:0072078 68 0.180
cerebellum development GO:0021549 77 0.177
positive regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901228 4 0.177
nephron development GO:0072006 109 0.176
visceral serous pericardium development GO:0061032 2 0.175
regulation of mechanoreceptor differentiation GO:0045631 5 0.174
epithelial cell maturation involved in prostate gland development GO:0060743 4 0.174
spinal cord association neuron differentiation GO:0021527 14 0.174
nose development GO:0043584 12 0.174
Mouse
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.173
nerve development GO:0021675 67 0.173
bundle of his development GO:0003166 4 0.172
heart valve morphogenesis GO:0003179 21 0.170
neuron projection guidance GO:0097485 141 0.170
Mouse
embryonic appendage morphogenesis GO:0035113 126 0.168
Mouse
cardiocyte differentiation GO:0035051 87 0.167
face development GO:0060324 38 0.166
Mouse
positive regulation of stem cell proliferation GO:2000648 59 0.166
body morphogenesis GO:0010171 45 0.165
Mouse
germ cell development GO:0007281 185 0.163
substrate independent telencephalic tangential interneuron migration GO:0021843 8 0.163
muscle tissue morphogenesis GO:0060415 53 0.162
positive regulation of synaptic plasticity GO:0031915 4 0.162
regulation of cell proliferation involved in heart morphogenesis GO:2000136 15 0.161
somatotropin secreting cell differentiation GO:0060126 4 0.161
negative regulation of epithelial cell proliferation involved in prostate gland development GO:0060770 7 0.161
positive regulation of transcription via serum response element binding GO:0010735 1 0.159
cell proliferation in forebrain GO:0021846 30 0.159
telencephalon cell migration GO:0022029 55 0.158
embryonic epithelial tube formation GO:0001838 130 0.157
tendon cell differentiation GO:0035990 4 0.156
substrate independent telencephalic tangential migration GO:0021826 8 0.155
negative regulation of cardiac chamber morphogenesis GO:1901220 2 0.155
regulation of nephron tubule epithelial cell differentiation GO:0072182 9 0.155
regulation of neuroblast proliferation GO:1902692 27 0.155
negative regulation of cell proliferation GO:0008285 296 0.155
positive regulation of cell development GO:0010720 237 0.154
negative regulation of neuron projection development GO:0010977 50 0.154
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.153
cardiac muscle cell development GO:0055013 39 0.152
mammary gland morphogenesis GO:0060443 54 0.151
development of primary sexual characteristics GO:0045137 143 0.151
negative regulation of neuron apoptotic process GO:0043524 92 0.151
organ growth GO:0035265 117 0.150
embryonic digit morphogenesis GO:0042733 56 0.150
ventricular cardiac muscle tissue development GO:0003229 38 0.148
central nervous system neuron development GO:0021954 67 0.147
negative regulation of wnt signaling pathway GO:0030178 73 0.145
negative regulation of oligodendrocyte differentiation GO:0048715 11 0.144
regulation of neural precursor cell proliferation GO:2000177 70 0.144
cell fate determination GO:0001709 32 0.142
negative regulation of cellular protein metabolic process GO:0032269 247 0.141
positive regulation of glial cell differentiation GO:0045687 21 0.141
embryonic heart tube morphogenesis GO:0003143 51 0.141
epithelial tube formation GO:0072175 130 0.141
telencephalon regionalization GO:0021978 14 0.140
negative regulation of oxidative phosphorylation uncoupler activity GO:2000276 2 0.140
regulation of chromatin modification GO:1903308 57 0.138
trabecula morphogenesis GO:0061383 40 0.138
olfactory bulb development GO:0021772 30 0.137
hematopoietic progenitor cell differentiation GO:0002244 143 0.136
cell differentiation involved in embryonic placenta development GO:0060706 26 0.136
apoptotic process involved in development GO:1902742 28 0.134
cardiac muscle cell differentiation GO:0055007 69 0.134
metanephros development GO:0001656 79 0.133
pericardium development GO:0060039 16 0.133
regulation of skeletal muscle fiber differentiation GO:1902809 3 0.132
epithelial cell proliferation involved in prostate gland development GO:0060767 11 0.132
regulation of organelle organization GO:0033043 289 0.132
gonad development GO:0008406 141 0.131
metanephric dct cell differentiation GO:0072240 3 0.131
negative regulation of protein modification process GO:0031400 163 0.130
negative regulation of phosphate metabolic process GO:0045936 184 0.130
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.130
negative regulation of osteoblast differentiation GO:0045668 30 0.130
regulation of tongue muscle cell differentiation GO:2001035 2 0.129
trachea cartilage morphogenesis GO:0060535 4 0.128
digestive tract morphogenesis GO:0048546 147 0.128
embryonic hindlimb morphogenesis GO:0035116 32 0.128
forelimb morphogenesis GO:0035136 40 0.126
carbohydrate metabolic process GO:0005975 230 0.126
cellular amine metabolic process GO:0044106 44 0.126
regulation of neuron differentiation GO:0045664 281 0.125
aortic valve morphogenesis GO:0003180 4 0.125
metencephalon development GO:0022037 89 0.125
rhombomere morphogenesis GO:0021593 2 0.125
negative regulation of type b pancreatic cell apoptotic process GO:2000675 3 0.125
mitochondrion organization GO:0007005 134 0.123
cell proliferation in external granule layer GO:0021924 10 0.123
negative regulation of epithelial cell proliferation GO:0050680 64 0.123
dendrite development GO:0016358 115 0.123
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.121
determination of dorsal ventral asymmetry GO:0048262 5 0.120
vascular wound healing GO:0061042 3 0.119
regulation of intestinal epithelial structure maintenance GO:0060730 1 0.119
regulation of fat cell differentiation GO:0045598 81 0.119
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus GO:1901522 7 0.118
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.117
Mouse
regulation of mesenchymal cell proliferation involved in ureter development GO:0072199 3 0.117
tube closure GO:0060606 91 0.116
muscle cell differentiation GO:0042692 261 0.116
embryonic placenta development GO:0001892 98 0.116
pituitary gland development GO:0021983 38 0.115
apoptotic process involved in morphogenesis GO:0060561 25 0.115
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.114
negative regulation of transferase activity GO:0051348 85 0.114
positive regulation of skeletal muscle cell differentiation GO:2001016 4 0.114
prostate gland stromal morphogenesis GO:0060741 2 0.114
paraxial mesodermal cell differentiation GO:0048342 2 0.113
regulation of epithelial cell proliferation involved in prostate gland development GO:0060768 10 0.113
b cell differentiation GO:0030183 78 0.112
his purkinje system development GO:0003164 4 0.112
negative regulation of cell fate specification GO:0009996 4 0.111
atrial cardiac muscle cell development GO:0055014 2 0.111
blastocyst development GO:0001824 80 0.111
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.110
cerebral cortex cell migration GO:0021795 44 0.109
negative regulation of notch signaling pathway GO:0045746 14 0.109
negative regulation of cellular amine metabolic process GO:0033239 1 0.108
response to steroid hormone GO:0048545 56 0.108
glial cell migration GO:0008347 7 0.107
regulation of transcription from rna polymerase ii promoter involved in ventral spinal cord interneuron specification GO:0021913 4 0.107
regulation of kidney development GO:0090183 40 0.107
regulation of chromosome organization GO:0033044 83 0.107
regulation of cardioblast proliferation GO:0003264 9 0.106
negative regulation of astrocyte differentiation GO:0048712 10 0.105
regulation of heart looping GO:1901207 1 0.105
endodermal cell fate commitment GO:0001711 12 0.105
bmp signaling pathway GO:0030509 93 0.104
Mouse
alpha beta t cell differentiation GO:0046632 69 0.104
mammary placode formation GO:0060596 4 0.104
interneuron migration from the subpallium to the cortex GO:0021830 7 0.103
olfactory pit development GO:0060166 3 0.103
Mouse
regulation of exit from mitosis GO:0007096 1 0.103
negative regulation of chromatin modification GO:1903309 19 0.102
regulation of notch signaling pathway GO:0008593 35 0.102
myeloid leukocyte differentiation GO:0002573 119 0.102
chondrocyte development GO:0002063 24 0.102
cartilage development GO:0051216 140 0.101
endocardial cushion formation GO:0003272 13 0.101
olfactory bulb interneuron differentiation GO:0021889 12 0.101
endocrine pancreas development GO:0031018 29 0.100
regulation of apoptotic process involved in outflow tract morphogenesis GO:1902256 2 0.100
cellular component assembly involved in morphogenesis GO:0010927 139 0.099
negative regulation of neuron death GO:1901215 98 0.098
astrocyte differentiation GO:0048708 43 0.098
somatic stem cell maintenance GO:0035019 47 0.098
cellular response to bmp stimulus GO:0071773 14 0.098
Mouse
rhombomere 5 development GO:0021571 4 0.098
male gonad development GO:0008584 88 0.098
organonitrogen compound biosynthetic process GO:1901566 192 0.097
striated muscle tissue development GO:0014706 293 0.097
mitochondrion distribution GO:0048311 4 0.097
connective tissue development GO:0061448 179 0.096
developmental maturation GO:0021700 193 0.096
aorta development GO:0035904 23 0.095
heart morphogenesis GO:0003007 178 0.095
regulation of secondary heart field cardioblast proliferation GO:0003266 9 0.094
forebrain cell migration GO:0021885 58 0.094
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 18 0.094
noradrenergic neuron differentiation GO:0003357 6 0.093
hindlimb morphogenesis GO:0035137 42 0.093
response to organic cyclic compound GO:0014070 198 0.093
cardiac atrium morphogenesis GO:0003209 23 0.092
head morphogenesis GO:0060323 34 0.092
Mouse
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.092
cardiac neural crest cell development involved in outflow tract morphogenesis GO:0061309 6 0.091
artery development GO:0060840 53 0.091
spermatogenesis GO:0007283 284 0.090
positive regulation of transcription from rna polymerase ii promoter by glucose GO:0000432 3 0.090
covalent chromatin modification GO:0016569 163 0.090
negative regulation of kinase activity GO:0033673 81 0.090
mating GO:0007618 27 0.089
visceral motor neuron differentiation GO:0021524 3 0.089
respiratory system process GO:0003016 25 0.089
enteroendocrine cell differentiation GO:0035883 16 0.089
nephric duct formation GO:0072179 4 0.089
negative regulation of cellular component organization GO:0051129 194 0.089
endocardial cushion development GO:0003197 26 0.089
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.088
cardioblast proliferation GO:0003263 8 0.088
cerebral cortex radially oriented cell migration GO:0021799 31 0.088
ventral spinal cord interneuron specification GO:0021521 11 0.088
cellular response to lipid GO:0071396 145 0.088
metanephric capsule formation GO:0072266 1 0.088
negative regulation of molecular function GO:0044092 258 0.088
kidney epithelium development GO:0072073 121 0.087
prostate gland epithelium morphogenesis GO:0060740 31 0.087
regulation of homeostatic process GO:0032844 182 0.087
positive regulation of semaphorin plexin signaling pathway GO:2001262 1 0.086
mesangial cell differentiation GO:0072007 4 0.086
positive regulation of cardiac muscle cell proliferation GO:0060045 15 0.086
eating behavior GO:0042755 15 0.086
embryonic olfactory bulb interneuron precursor migration GO:0021831 2 0.086
cardiac left ventricle formation GO:0003218 1 0.086
formation of primary germ layer GO:0001704 77 0.086
regulation of cardiac chamber formation GO:1901210 1 0.085
axonogenesis GO:0007409 274 0.085
Mouse
mesonephric tubule development GO:0072164 94 0.083
positive regulation of stem cell differentiation GO:2000738 23 0.082
blastocyst formation GO:0001825 33 0.082
carbon catabolite repression of transcription GO:0045013 1 0.081
muscle cell development GO:0055001 133 0.081
negative regulation of intracellular signal transduction GO:1902532 167 0.081
regulation of peptidyl lysine acetylation GO:2000756 22 0.081
endocardial cushion morphogenesis GO:0003203 18 0.081
regulation of branching involved in ureteric bud morphogenesis GO:0090189 22 0.081
positive regulation of ossification GO:0045778 47 0.081
positive regulation of organelle organization GO:0010638 128 0.081
prostate gland development GO:0030850 48 0.080
cerebral cortex gabaergic interneuron development GO:0021894 6 0.080
multi multicellular organism process GO:0044706 109 0.080
compound eye development GO:0048749 1 0.080
regulation of keratinocyte differentiation GO:0045616 11 0.079
neuron fate determination GO:0048664 9 0.079
facial nucleus development GO:0021754 2 0.079
nephron epithelium development GO:0072009 92 0.079
positive regulation of kidney development GO:0090184 28 0.079
atrioventricular bundle cell differentiation GO:0003167 1 0.079
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.078
ameboidal type cell migration GO:0001667 128 0.078
regulation of myeloid leukocyte differentiation GO:0002761 58 0.078
gastrulation GO:0007369 116 0.077
metanephric nephron tubule formation GO:0072289 4 0.077
cardiac cell development GO:0055006 41 0.077
commitment of neuronal cell to specific neuron type in forebrain GO:0021902 7 0.077
biomineral tissue development GO:0031214 64 0.077
organic hydroxy compound biosynthetic process GO:1901617 77 0.076
mitochondrial transport GO:0006839 36 0.076
cartilage condensation GO:0001502 18 0.076
myoblast differentiation GO:0045445 52 0.075
regulation of chromatin organization GO:1902275 57 0.075
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 0.075
learning or memory GO:0007611 148 0.075
apoptotic process involved in heart morphogenesis GO:0003278 5 0.075
negative regulation of dna binding GO:0043392 20 0.075
neural tube formation GO:0001841 108 0.075
neural plate development GO:0001840 12 0.074
sclerotome development GO:0061056 4 0.074
regulation of cell motility GO:2000145 236 0.074
regulation of cell division GO:0051302 76 0.074
ventral spinal cord interneuron fate commitment GO:0060579 14 0.074
neuron apoptotic process GO:0051402 142 0.073
auditory receptor cell differentiation GO:0042491 37 0.073
establishment of epithelial cell apical basal polarity GO:0045198 5 0.073
endodermal cell fate specification GO:0001714 4 0.072
cell fate determination involved in pattern specification GO:0060582 1 0.072
neuron maturation GO:0042551 29 0.072
skin development GO:0043588 220 0.072
cell recognition GO:0008037 83 0.072
muscle system process GO:0003012 141 0.072
regulation of reproductive process GO:2000241 66 0.072
positive regulation of tongue muscle cell differentiation GO:2001037 2 0.071
multi organism behavior GO:0051705 62 0.071
amacrine cell differentiation GO:0035881 5 0.070
regulation of neuron maturation GO:0014041 5 0.070
cerebellar cortex development GO:0021695 48 0.070
kidney morphogenesis GO:0060993 83 0.069

Dlx2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.085
nervous system disease DOID:863 0 0.085