Mus musculus

19 known processes

Dok1

docking protein 1

(Aliases: AW557123,p62DOK)

Dok1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
optic placode formation involved in camera type eye formation GO:0046619 2 0.998
Mouse
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.982
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.980
Mouse
regulation of transferase activity GO:0051338 263 0.977
Mouse
regulation of kinase activity GO:0043549 249 0.975
Mouse
negative regulation of kinase activity GO:0033673 81 0.964
regulation of protein kinase activity GO:0045859 232 0.956
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.956
Mouse
cellular response to growth factor stimulus GO:0071363 197 0.954
Mouse
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.954
negative regulation of phagocytosis GO:0050765 4 0.952
optic placode formation GO:0001743 2 0.950
Mouse
substrate dependent cell migration cell extension GO:0006930 4 0.940
positive regulation of mapk cascade GO:0043410 170 0.934
Mouse
leukocyte proliferation GO:0070661 172 0.931
regulation of cellular amine metabolic process GO:0033238 20 0.927
regulation of erk1 and erk2 cascade GO:0070372 71 0.919
Mouse
response to growth factor GO:0070848 198 0.916
Mouse
organ induction GO:0001759 21 0.911
Mouse
peptidyl tyrosine modification GO:0018212 145 0.900
immune response activating signal transduction GO:0002757 116 0.880
negative regulation of phosphorus metabolic process GO:0010563 184 0.876
release of sequestered calcium ion into cytosol GO:0051209 42 0.867
response to peptide GO:1901652 136 0.863
regulation of actin filament based process GO:0032970 99 0.863
regulation of mapk cascade GO:0043408 248 0.852
Mouse
t cell proliferation GO:0042098 120 0.851
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.847
Mouse
actin cytoskeleton organization GO:0030036 220 0.842
small gtpase mediated signal transduction GO:0007264 97 0.836
erk1 and erk2 cascade GO:0070371 77 0.835
Mouse
regulation of actin filament polymerization GO:0030833 38 0.828
regulation of phospholipase c activity GO:1900274 3 0.820
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.819
Mouse
negative regulation of molecular function GO:0044092 258 0.812
amine metabolic process GO:0009308 45 0.809
mapk cascade GO:0000165 281 0.807
Mouse
morphogenesis of a branching epithelium GO:0061138 193 0.805
Mouse
substrate dependent cell migration GO:0006929 18 0.805
epithelial cell development GO:0002064 159 0.803
Mouse
muscle cell differentiation GO:0042692 261 0.800
response to organonitrogen compound GO:0010243 246 0.792
regulation of map kinase activity GO:0043405 120 0.791
Mouse
activation of mapk activity GO:0000187 59 0.786
Mouse
positive regulation of kinase activity GO:0033674 155 0.784
Mouse
regulation of mast cell activation involved in immune response GO:0033006 17 0.771
peptidyl amino acid modification GO:0018193 336 0.771
cellular response to organonitrogen compound GO:0071417 145 0.771
leukocyte differentiation GO:0002521 342 0.754
cellular amine metabolic process GO:0044106 44 0.753
cellular amino acid metabolic process GO:0006520 103 0.747
actin polymerization or depolymerization GO:0008154 54 0.746
negative regulation of phosphorylation GO:0042326 166 0.740
regulation of interleukin 2 secretion GO:1900040 6 0.740
gland development GO:0048732 330 0.736
Mouse
prostate gland development GO:0030850 48 0.735
Mouse
lymphocyte differentiation GO:0030098 242 0.729
positive regulation of leukocyte apoptotic process GO:2000108 21 0.727
positive regulation of protein modification process GO:0031401 299 0.706
Mouse
glial cell differentiation GO:0010001 131 0.706
positive regulation of transferase activity GO:0051347 167 0.706
Mouse
cytosolic calcium ion transport GO:0060401 48 0.699
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.694
calcium ion transport GO:0006816 159 0.694
lens development in camera type eye GO:0002088 62 0.694
Mouse
regulation of protein complex assembly GO:0043254 83 0.689
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.687
prostate glandular acinus development GO:0060525 12 0.673
Mouse
developmental induction GO:0031128 34 0.668
Mouse
positive regulation of apoptotic process GO:0043065 217 0.647
cellular ketone metabolic process GO:0042180 84 0.643
negative regulation of transferase activity GO:0051348 85 0.637
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.632
positive regulation of map kinase activity GO:0043406 84 0.630
Mouse
regulation of actin polymerization or depolymerization GO:0008064 45 0.625
regulation of lymphocyte apoptotic process GO:0070228 41 0.625
regulation of homeostatic process GO:0032844 182 0.625
b cell proliferation GO:0042100 53 0.620
positive regulation of cell death GO:0010942 224 0.615
antigen receptor mediated signaling pathway GO:0050851 64 0.612
positive regulation of programmed cell death GO:0043068 218 0.607
ventricular septum development GO:0003281 42 0.604
Mouse
regulation of cytokine production GO:0001817 266 0.600
forebrain development GO:0030900 302 0.598
Mouse
regulation of protein transport GO:0051223 163 0.598
regulation of cytoskeleton organization GO:0051493 122 0.598
regulation of protein serine threonine kinase activity GO:0071900 157 0.594
Mouse
regulation of t cell activation GO:0050863 170 0.592
negative regulation of mapk cascade GO:0043409 65 0.592
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.587
lymphocyte proliferation GO:0046651 164 0.585
regulation of metal ion transport GO:0010959 106 0.580
embryonic organ morphogenesis GO:0048562 276 0.577
Mouse
divalent metal ion transport GO:0070838 172 0.561
calcium ion transport into cytosol GO:0060402 48 0.559
cell cell signaling involved in cell fate commitment GO:0045168 35 0.559
Mouse
negative regulation of homeostatic process GO:0032845 71 0.556
substrate adhesion dependent cell spreading GO:0034446 30 0.552
regulation of vesicle mediated transport GO:0060627 139 0.550
branching involved in prostate gland morphogenesis GO:0060442 15 0.547
Mouse
negative regulation of erk1 and erk2 cascade GO:0070373 21 0.535
regulation of secretion by cell GO:1903530 249 0.534
regulation of actin cytoskeleton organization GO:0032956 84 0.532
t cell differentiation GO:0030217 174 0.529
negative regulation of leukocyte differentiation GO:1902106 51 0.525
prostate gland morphogenesis GO:0060512 32 0.523
Mouse
mast cell degranulation GO:0043303 19 0.511
insulin receptor signaling pathway GO:0008286 49 0.506
neural precursor cell proliferation GO:0061351 121 0.506
Mouse
b cell differentiation GO:0030183 78 0.503
b cell receptor signaling pathway GO:0050853 20 0.501
regulation of organ formation GO:0003156 34 0.498
Mouse
morphogenesis of a branching structure GO:0001763 203 0.488
Mouse
regulation of mast cell degranulation GO:0043304 16 0.488
regulation of engulfment of apoptotic cell GO:1901074 2 0.486
cellular metal ion homeostasis GO:0006875 151 0.483
regulation of cell motility GO:2000145 236 0.478
epithelial cell proliferation GO:0050673 174 0.473
Mouse
cardiac septum development GO:0003279 59 0.472
Mouse
homeostasis of number of cells GO:0048872 210 0.470
dendrite development GO:0016358 115 0.464
sequestering of calcium ion GO:0051208 18 0.464
exocytosis GO:0006887 121 0.462
regulation of organelle organization GO:0033043 289 0.462
leukocyte activation involved in immune response GO:0002366 126 0.456
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.450
cellular response to peptide GO:1901653 92 0.446
regulation of calcium ion transport GO:0051924 69 0.445
b cell apoptotic process GO:0001783 19 0.441
positive regulation of secretion by cell GO:1903532 114 0.441
ras protein signal transduction GO:0007265 77 0.435
response to fibroblast growth factor GO:0071774 47 0.435
Mouse
regulation of cell adhesion GO:0030155 154 0.433
cell activation involved in immune response GO:0002263 126 0.428
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.427
cytoplasmic transport GO:0016482 234 0.426
sensory organ morphogenesis GO:0090596 242 0.426
Mouse
regulation of epithelial cell proliferation GO:0050678 141 0.422
Mouse
cell aging GO:0007569 35 0.422
regulation of t cell proliferation GO:0042129 92 0.421
cellular response to biotic stimulus GO:0071216 92 0.420
negative regulation of cell proliferation GO:0008285 296 0.419
striated muscle cell development GO:0055002 125 0.419
positive regulation of cell migration GO:0030335 109 0.419
digestive system development GO:0055123 200 0.418
Mouse
regulation of lymphocyte proliferation GO:0050670 117 0.418
positive regulation of cellular amine metabolic process GO:0033240 5 0.418
t cell receptor signaling pathway GO:0050852 46 0.416
activation of immune response GO:0002253 138 0.405
cellular response to peptide hormone stimulus GO:0071375 92 0.404
negative regulation of map kinase activity GO:0043407 34 0.397
negative regulation of phosphate metabolic process GO:0045936 184 0.397
prostate glandular acinus morphogenesis GO:0060526 7 0.397
Mouse
negative regulation of protein modification process GO:0031400 163 0.393
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.393
cell cell junction organization GO:0045216 72 0.388
regulation of cellular component size GO:0032535 121 0.386
glycosyl compound catabolic process GO:1901658 206 0.381
divalent inorganic cation transport GO:0072511 178 0.381
response to peptide hormone GO:0043434 127 0.380
response to lipopolysaccharide GO:0032496 128 0.376
negative regulation of endocytosis GO:0045806 12 0.374
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.367
negative regulation of insulin receptor signaling pathway GO:0046627 14 0.367
single organismal cell cell adhesion GO:0016337 131 0.366
cellular lipid metabolic process GO:0044255 323 0.364
regulation of organ morphogenesis GO:2000027 144 0.363
Mouse
positive regulation of protein kinase activity GO:0045860 144 0.362
Mouse
peptidyl tyrosine phosphorylation GO:0018108 143 0.358
prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis GO:0060527 7 0.358
Mouse
positive regulation of mast cell degranulation GO:0043306 10 0.357
i kappab kinase nf kappab signaling GO:0007249 85 0.354
regulation of leukocyte proliferation GO:0070663 121 0.353
positive regulation of leukocyte differentiation GO:1902107 86 0.352
sequestering of metal ion GO:0051238 19 0.350
regulation of b cell apoptotic process GO:0002902 13 0.348
myeloid cell homeostasis GO:0002262 114 0.346
segmentation GO:0035282 93 0.339
Mouse
regulation of protein localization GO:0032880 231 0.337
calcium mediated signaling GO:0019722 46 0.333
regulation of ion transport GO:0043269 215 0.333
negative regulation of protein phosphorylation GO:0001933 126 0.329
regulation of leukocyte apoptotic process GO:2000106 56 0.326
negative regulation of protein metabolic process GO:0051248 282 0.324
positive regulation of t cell activation GO:0050870 101 0.324
regulation of anatomical structure size GO:0090066 178 0.321
regulation of insulin receptor signaling pathway GO:0046626 21 0.318
lamellipodium organization GO:0097581 29 0.316
protein autophosphorylation GO:0046777 61 0.310
b cell activation GO:0042113 161 0.307
regulation of cellular ketone metabolic process GO:0010565 66 0.305
spleen development GO:0048536 39 0.305
bone remodeling GO:0046849 53 0.305
digestive tract morphogenesis GO:0048546 147 0.303
Mouse
negative regulation of myeloid leukocyte differentiation GO:0002762 20 0.298
stem cell proliferation GO:0072089 117 0.297
Mouse
negative regulation of phospholipase activity GO:0010519 4 0.295
b cell homeostasis GO:0001782 34 0.295
cation homeostasis GO:0055080 212 0.295
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.292
positive regulation of cellular component biogenesis GO:0044089 94 0.291
phosphatidylinositol biosynthetic process GO:0006661 15 0.281
embryonic axis specification GO:0000578 30 0.280
Mouse
anatomical structure homeostasis GO:0060249 145 0.280
regulation of ion homeostasis GO:2000021 64 0.277
divalent inorganic cation homeostasis GO:0072507 138 0.277
regulation of secretion GO:0051046 274 0.277
endocytosis GO:0006897 168 0.276
negative regulation of bone remodeling GO:0046851 6 0.274
bone resorption GO:0045453 38 0.274
immune response regulating signaling pathway GO:0002764 125 0.273
regulation of binding GO:0051098 111 0.271
tyrosine phosphorylation of stat5 protein GO:0042506 9 0.270
cellular protein complex assembly GO:0043623 116 0.268
regulation of cytoplasmic transport GO:1903649 112 0.266
second messenger mediated signaling GO:0019932 73 0.262
interleukin 2 secretion GO:0070970 7 0.262
positive regulation of cell projection organization GO:0031346 95 0.256
negative regulation of myeloid cell differentiation GO:0045638 38 0.255
regulation of lymphocyte differentiation GO:0045619 107 0.254
embryonic camera type eye development GO:0031076 36 0.254
Mouse
learning or memory GO:0007611 148 0.252
regulation of leukocyte differentiation GO:1902105 159 0.252
positive regulation of interferon gamma secretion GO:1902715 3 0.251
regulation of cell cycle GO:0051726 281 0.250
negative regulation of growth GO:0045926 99 0.248
macromolecule catabolic process GO:0009057 281 0.247
myotube differentiation GO:0014902 105 0.247
leukocyte apoptotic process GO:0071887 71 0.245
protein polymerization GO:0051258 57 0.241
regulation of cytokine secretion GO:0050707 61 0.241
cardiac ventricle development GO:0003231 83 0.240
Mouse
leukocyte homeostasis GO:0001776 79 0.240
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.239
monocarboxylic acid metabolic process GO:0032787 191 0.239
chemotaxis GO:0006935 247 0.238
cellular response to lipid GO:0071396 145 0.237
fc receptor mediated stimulatory signaling pathway GO:0002431 4 0.237
negative regulation of cellular protein metabolic process GO:0032269 247 0.235
response to oxidative stress GO:0006979 123 0.234
positive regulation of organelle organization GO:0010638 128 0.234
camera type eye development GO:0043010 266 0.232
Mouse
positive regulation of intracellular transport GO:0032388 70 0.231
calcium ion homeostasis GO:0055074 127 0.230
leukocyte degranulation GO:0043299 27 0.229
protein localization to membrane GO:0072657 108 0.229
regulation of erythrocyte differentiation GO:0045646 23 0.227
gastrulation with mouth forming second GO:0001702 29 0.227
Mouse
axonogenesis GO:0007409 274 0.226
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.226
negative regulation of ras protein signal transduction GO:0046580 18 0.224
regulation of intracellular transport GO:0032386 159 0.222
negative regulation of immune system process GO:0002683 209 0.222
muscle fiber development GO:0048747 76 0.221
cellular calcium ion homeostasis GO:0006874 119 0.221
ribonucleoside catabolic process GO:0042454 206 0.220
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.220
dendritic spine maintenance GO:0097062 4 0.219
cellular homeostasis GO:0019725 240 0.218
response to insulin GO:0032868 100 0.216
negative regulation of cell migration GO:0030336 59 0.214
muscle cell development GO:0055001 133 0.212
regulation of establishment of protein localization GO:0070201 181 0.212
positive regulation of secretion GO:0051047 130 0.211
cell junction organization GO:0034330 77 0.208
tissue remodeling GO:0048771 102 0.208
positive regulation of b cell receptor signaling pathway GO:0050861 4 0.207
positive regulation of protein complex assembly GO:0031334 45 0.206
wnt signaling pathway GO:0016055 188 0.204
ectodermal placode development GO:0071696 16 0.204
Mouse
lymphocyte homeostasis GO:0002260 64 0.203
lymphocyte apoptotic process GO:0070227 54 0.200
positive regulation of cytokine production GO:0001819 174 0.199
regulation of neuron projection development GO:0010975 169 0.198
leukocyte mediated immunity GO:0002443 174 0.198
positive regulation of stem cell differentiation GO:2000738 23 0.196
defense response to bacterium GO:0042742 119 0.196
multicellular organismal homeostasis GO:0048871 164 0.194
regulation of cellular component biogenesis GO:0044087 181 0.193
immune effector process GO:0002252 321 0.192
positive regulation of cytokine secretion GO:0050715 41 0.192
cell fate commitment GO:0045165 210 0.187
Mouse
positive regulation of myeloid leukocyte mediated immunity GO:0002888 14 0.186
negative regulation of osteoclast differentiation GO:0045671 12 0.180
negative regulation of intracellular transport GO:0032387 38 0.179
protein modification by small protein conjugation GO:0032446 187 0.178
negative regulation of granulocyte differentiation GO:0030853 3 0.178
positive regulation of lymphocyte activation GO:0051251 140 0.176
mitotic cell cycle process GO:1903047 159 0.175
positive regulation of neuron projection development GO:0010976 79 0.175
purine nucleotide metabolic process GO:0006163 302 0.174
adaptive immune response GO:0002250 155 0.172
regulation of neuron differentiation GO:0045664 281 0.172
positive regulation of neuron differentiation GO:0045666 141 0.171
carbohydrate derivative catabolic process GO:1901136 231 0.170
regulation of cell projection organization GO:0031344 206 0.170
dna endoreduplication GO:0042023 4 0.165
nucleoside triphosphate metabolic process GO:0009141 230 0.165
positive regulation of cell motility GO:2000147 116 0.165
epithelial tube morphogenesis GO:0060562 303 0.164
cellularization GO:0007349 1 0.163
response to transforming growth factor beta GO:0071559 88 0.162
nucleobase containing small molecule metabolic process GO:0055086 352 0.162
cellular response to acid chemical GO:0071229 68 0.160
alpha beta t cell differentiation GO:0046632 69 0.158
glycosyl compound metabolic process GO:1901657 246 0.156
negative regulation of b cell activation GO:0050869 27 0.155
regulation of cellular catabolic process GO:0031329 242 0.155
myeloid leukocyte differentiation GO:0002573 119 0.155
membrane organization GO:0061024 245 0.155
t cell activation GO:0042110 289 0.155
regulation of phospholipase activity GO:0010517 9 0.154
negative regulation of intracellular signal transduction GO:1902532 167 0.154
negative regulation of cell activation GO:0050866 111 0.153
cellular response to lipopolysaccharide GO:0071222 77 0.153
cell type specific apoptotic process GO:0097285 268 0.152
defense response to other organism GO:0098542 197 0.151
positive regulation of leukocyte degranulation GO:0043302 10 0.149
intracellular protein transport GO:0006886 204 0.148
ectodermal placode morphogenesis GO:0071697 16 0.148
Mouse
regulation of cellular response to stress GO:0080135 159 0.145
aspartate family amino acid metabolic process GO:0009066 10 0.144
negative regulation of toll like receptor signaling pathway GO:0034122 14 0.144
cytokine secretion GO:0050663 72 0.143
cellular component assembly involved in morphogenesis GO:0010927 139 0.141
regulation of cell activation GO:0050865 289 0.141
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.140
guanosine containing compound catabolic process GO:1901069 144 0.136
detection of stimulus GO:0051606 84 0.135
gastrulation GO:0007369 116 0.135
Mouse
cellular divalent inorganic cation homeostasis GO:0072503 127 0.135
negative regulation of cytokine production GO:0001818 84 0.134
negative regulation of leukocyte proliferation GO:0070664 46 0.132
morphogenesis of a polarized epithelium GO:0001738 37 0.132
response to decreased oxygen levels GO:0036293 59 0.131
germ cell development GO:0007281 185 0.131
response to acid chemical GO:0001101 111 0.131
skeletal muscle organ development GO:0060538 163 0.130
cell adhesion GO:0007155 329 0.129
ion transmembrane transport GO:0034220 361 0.129
positive regulation of phospholipase c activity GO:0010863 2 0.128
negative regulation of cellular component organization GO:0051129 194 0.127
positive regulation of gtp catabolic process GO:0033126 85 0.127
erythrocyte differentiation GO:0030218 88 0.126
regulation of protein binding GO:0043393 60 0.126
response to oxygen levels GO:0070482 62 0.124
gtp catabolic process GO:0006184 143 0.124
negative regulation of cell cycle GO:0045786 123 0.124
neutrophil differentiation GO:0030223 3 0.123
developmental maturation GO:0021700 193 0.123
positive regulation of apoptotic signaling pathway GO:2001235 95 0.123
phagocytosis GO:0006909 66 0.123
organelle localization GO:0051640 179 0.121
extrinsic apoptotic signaling pathway GO:0097191 126 0.121
gliogenesis GO:0042063 141 0.120
negative regulation of cellular response to insulin stimulus GO:1900077 16 0.119
cell substrate adhesion GO:0031589 130 0.119
positive regulation of mitotic cell cycle GO:0045931 41 0.119
regulation of protein catabolic process GO:0042176 108 0.117
regulation of hydrolase activity GO:0051336 246 0.116
cellular chemical homeostasis GO:0055082 215 0.116
toll like receptor signaling pathway GO:0002224 38 0.116
actin filament polymerization GO:0030041 44 0.115
carbohydrate metabolic process GO:0005975 230 0.115
purine ribonucleoside metabolic process GO:0046128 241 0.114
cytosolic calcium ion homeostasis GO:0051480 70 0.113
regulation of endocytosis GO:0030100 69 0.113
signal transduction by p53 class mediator GO:0072331 51 0.113
male gamete generation GO:0048232 285 0.110
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.110
positive regulation of t cell differentiation GO:0045582 52 0.109
response to hypoxia GO:0001666 58 0.109
cellular nitrogen compound catabolic process GO:0044270 280 0.108
embryonic camera type eye formation GO:0060900 9 0.108
Mouse
myeloid leukocyte activation GO:0002274 83 0.108
cellular response to insulin stimulus GO:0032869 78 0.108
regulation of cellular amino acid metabolic process GO:0006521 5 0.108
ectodermal placode formation GO:0060788 16 0.107
Mouse
single organism cell adhesion GO:0098602 156 0.107
protein localization to organelle GO:0033365 185 0.107
l serine metabolic process GO:0006563 2 0.106
positive regulation of non canonical wnt signaling pathway GO:2000052 6 0.105
lymphocyte activation involved in immune response GO:0002285 93 0.105
associative learning GO:0008306 61 0.104
regulation of proteolysis GO:0030162 164 0.103
regulation of dendritic cell apoptotic process GO:2000668 3 0.103
regulated secretory pathway GO:0045055 32 0.102
regulation of leukocyte mediated immunity GO:0002703 104 0.102
protein catabolic process GO:0030163 221 0.101
engulfment of apoptotic cell GO:0043652 3 0.101
metencephalon development GO:0022037 89 0.101
organophosphate biosynthetic process GO:0090407 122 0.100
regulation of mitotic cell cycle GO:0007346 126 0.100
organic cyclic compound catabolic process GO:1901361 295 0.099
regulation of jak stat cascade GO:0046425 34 0.099
regulation of intracellular protein transport GO:0033157 82 0.098
purine ribonucleoside catabolic process GO:0046130 205 0.097
regulation of t cell differentiation GO:0045580 83 0.097
cation transport GO:0006812 399 0.097
organophosphate catabolic process GO:0046434 232 0.096
protein modification by small protein conjugation or removal GO:0070647 207 0.096
small molecule biosynthetic process GO:0044283 132 0.095
positive regulation of protein secretion GO:0050714 52 0.095
purine ribonucleotide metabolic process GO:0009150 290 0.094
reactive oxygen species metabolic process GO:0072593 84 0.093
nucleoside catabolic process GO:0009164 206 0.093
phospholipid metabolic process GO:0006644 87 0.093
cell maturation GO:0048469 127 0.092
positive regulation of keratinocyte proliferation GO:0010838 4 0.091
myeloid cell differentiation GO:0030099 233 0.091
regulation of jun kinase activity GO:0043506 40 0.090
regulation of cell migration GO:0030334 219 0.090
organonitrogen compound biosynthetic process GO:1901566 192 0.090
maintenance of location GO:0051235 89 0.090
neuroblast proliferation GO:0007405 49 0.090
Mouse
regulation of leukocyte degranulation GO:0043300 20 0.090
regulation of myeloid cell differentiation GO:0045637 96 0.090
myeloid leukocyte mediated immunity GO:0002444 42 0.089
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.089
pancreatic pp cell fate commitment GO:0003329 2 0.089
protein ubiquitination GO:0016567 171 0.089
learning GO:0007612 98 0.089
cytokine production GO:0001816 319 0.089
regulation of cellular response to insulin stimulus GO:1900076 30 0.088
positive regulation of lipid metabolic process GO:0045834 40 0.088
regulation of membrane potential GO:0042391 192 0.088
nucleoside triphosphate catabolic process GO:0009143 205 0.087
regulation of cd24 biosynthetic process GO:2000559 1 0.086
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.086
regulation of calcium ion transport into cytosol GO:0010522 31 0.085
response to ionizing radiation GO:0010212 42 0.085
protein localization to nucleus GO:0034504 121 0.085
regulation of cell cycle process GO:0010564 160 0.085
compound eye development GO:0048749 1 0.084
regulation of tissue remodeling GO:0034103 38 0.084
leukocyte migration GO:0050900 124 0.084
purine nucleoside triphosphate metabolic process GO:0009144 226 0.084
cellular response to hormone stimulus GO:0032870 150 0.084
positive regulation of leukocyte proliferation GO:0070665 73 0.084
detection of mechanical stimulus involved in sensory perception of pain GO:0050966 4 0.083
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.083
cell chemotaxis GO:0060326 81 0.083
positive regulation of cell development GO:0010720 237 0.083
deltoid tuberosity development GO:0035993 3 0.083
cellular response to gamma radiation GO:0071480 4 0.082
interleukin 6 production GO:0032635 58 0.082
negative regulation of cellular senescence GO:2000773 3 0.082
cardiac chamber development GO:0003205 108 0.082
Mouse
regulation of wnt signaling pathway GO:0030111 123 0.082
negative regulation of synapse assembly GO:0051964 3 0.081
tissue homeostasis GO:0001894 115 0.081
actin filament bundle assembly GO:0051017 40 0.080
blood vessel morphogenesis GO:0048514 285 0.080
cellular response to molecule of bacterial origin GO:0071219 83 0.080
positive regulation of t cell proliferation GO:0042102 52 0.079
erbb signaling pathway GO:0038127 32 0.078
response to retinoic acid GO:0032526 56 0.078
nucleotide metabolic process GO:0009117 332 0.077
regulation of exit from mitosis GO:0007096 1 0.077
regulation of protein secretion GO:0050708 82 0.077
stem cell differentiation GO:0048863 268 0.077
synaptic transmission GO:0007268 329 0.076
regionalization GO:0003002 337 0.076
Mouse
alcohol metabolic process GO:0006066 116 0.076
tripartite regional subdivision GO:0007351 9 0.076
Mouse
negative regulation of cell motility GO:2000146 61 0.076
regulation of phosphatidylinositol 3 kinase activity GO:0043551 14 0.075
b 1a b cell differentiation GO:0002337 2 0.075
unsaturated fatty acid metabolic process GO:0033559 31 0.074
podosome assembly GO:0071800 6 0.074
molting cycle GO:0042303 90 0.074
negative regulation of lymphocyte proliferation GO:0050672 45 0.073
guanosine containing compound metabolic process GO:1901068 144 0.073
positive regulation of podosome assembly GO:0071803 3 0.073
regulation of hemostasis GO:1900046 28 0.073
interferon gamma production GO:0032609 67 0.073
neuron neuron synaptic transmission GO:0007270 69 0.072
regulation of purine nucleotide metabolic process GO:1900542 169 0.072
neuron migration GO:0001764 122 0.071
negative regulation of b cell receptor signaling pathway GO:0050859 4 0.071
organelle assembly GO:0070925 177 0.070
digestive tract development GO:0048565 190 0.070
Mouse
actin filament organization GO:0007015 113 0.070
lysosome localization GO:0032418 20 0.070
cell cycle g1 s phase transition GO:0044843 57 0.069
positive regulation of erythrocyte differentiation GO:0045648 11 0.069
angiogenesis GO:0001525 201 0.069
microtubule based process GO:0007017 236 0.068
positive regulation of lymphocyte apoptotic process GO:0070230 13 0.068
extracellular matrix organization GO:0030198 147 0.067

Dok1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.192
amino acid metabolic disorder DOID:9252 0 0.192
inherited metabolic disorder DOID:655 0 0.192
cancer DOID:162 0 0.082
disease of cellular proliferation DOID:14566 0 0.082
organ system cancer DOID:0050686 0 0.082