Mus musculus

180 known processes

Egr1

early growth response 1

(Aliases: Krox-24,Zif268,Krox24,egr,Zfp-6,Egr-1,Zenk,NGFI-A,NGF1-A,TIS8,NGFIA,A530045N19Rik,ETR103,Krox-1)

Egr1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of ovulation GO:0060278 3 0.997
Worm
placenta development GO:0001890 140 0.903
axonogenesis GO:0007409 274 0.891
Mouse
regulation of brown fat cell differentiation GO:0090335 5 0.872
positive regulation of nuclear transcribed mrna poly a tail shortening GO:0060213 4 0.862
skeletal muscle cell differentiation GO:0035914 66 0.850
myeloid cell differentiation GO:0030099 233 0.842
regulation of cyclin dependent protein serine threonine kinase activity involved in g2 m transition of mitotic cell cycle GO:0031660 1 0.836
labyrinthine layer development GO:0060711 49 0.812
blood vessel morphogenesis GO:0048514 285 0.796
Mouse
transforming growth factor beta2 production GO:0032906 2 0.777
cellular response to gamma radiation GO:0071480 4 0.772
vitellogenesis GO:0007296 2 0.765
negative regulation of ovulation GO:0060280 1 0.763
Worm
positive regulation of transforming growth factor beta2 production GO:0032915 2 0.758
negative regulation of response to wounding GO:1903035 77 0.754
negative regulation of molecular function GO:0044092 258 0.749
Worm
gland development GO:0048732 330 0.748
Mouse
mapk cascade GO:0000165 281 0.747
Worm
positive regulation of osteoclast differentiation GO:0045672 15 0.745
central nervous system neuron development GO:0021954 67 0.738
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.738
positive regulation of cell death GO:0010942 224 0.734
Rat
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.724
regulation of fat cell differentiation GO:0045598 81 0.717
osteoclast differentiation GO:0030316 62 0.701
positive regulation of apoptotic process GO:0043065 217 0.700
Rat
regulation of osteoclast differentiation GO:0045670 36 0.685
regulation of dna templated transcription in response to stress GO:0043620 9 0.682
regulation of neuron apoptotic process GO:0043523 122 0.668
Rat
positive regulation of leukocyte differentiation GO:1902107 86 0.658
Mouse
negative regulation of cell proliferation GO:0008285 296 0.654
Mouse
fat cell differentiation GO:0045444 160 0.652
Mouse
metanephric glomerular mesangium development GO:0072223 3 0.650
Mouse Rat
regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061418 2 0.649
positive regulation of programmed cell death GO:0043068 218 0.639
Rat
positive regulation of myeloid leukocyte differentiation GO:0002763 26 0.631
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900153 5 0.625
leukocyte differentiation GO:0002521 342 0.604
axon regeneration GO:0031103 12 0.603
monosaccharide biosynthetic process GO:0046364 44 0.601
positive regulation of male gonad development GO:2000020 6 0.601
Mouse
carbohydrate biosynthetic process GO:0016051 74 0.600
negative regulation of fat cell differentiation GO:0045599 36 0.596
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.586
Worm
regulation of leukocyte differentiation GO:1902105 159 0.578
Mouse
decidualization GO:0046697 10 0.572
regulation of protein serine threonine kinase activity GO:0071900 157 0.570
Worm
negative regulation of protein kinase activity by regulation of protein phosphorylation GO:0044387 2 0.567
response to growth factor GO:0070848 198 0.564
Rat
negative regulation of neuron death GO:1901215 98 0.555
organ growth GO:0035265 117 0.552
Mouse
embryonic placenta development GO:0001892 98 0.543
negative regulation of multi organism process GO:0043901 68 0.543
Worm
negative regulation of metanephric glomerular mesangial cell proliferation GO:0072302 1 0.542
Mouse
neuron apoptotic process GO:0051402 142 0.535
Rat
muscle tissue development GO:0060537 308 0.532
regulation of chromosome organization GO:0033044 83 0.531
stem cell maintenance GO:0019827 130 0.515
thorax and anterior abdomen determination GO:0007356 1 0.515
Mouse
placenta blood vessel development GO:0060674 31 0.514
myeloid leukocyte differentiation GO:0002573 119 0.511
regulation of organelle organization GO:0033043 289 0.504
ovulation GO:0030728 15 0.500
Worm
negative regulation of protein metabolic process GO:0051248 282 0.496
Worm
negative regulation of phosphorylation GO:0042326 166 0.493
Worm
adrenal cortex development GO:0035801 2 0.492
Mouse
cellular response to inorganic substance GO:0071241 37 0.485
negative regulation of metanephric glomerulus development GO:0072299 1 0.472
Mouse
axon guidance GO:0007411 141 0.468
Mouse
regulation of female gonad development GO:2000194 7 0.466
Mouse
rhombomere 5 formation GO:0021666 1 0.466
Mouse
regulation of respiratory burst involved in inflammatory response GO:0060264 2 0.458
response to organonitrogen compound GO:0010243 246 0.458
skeletal muscle organ development GO:0060538 163 0.451
blastocyst development GO:0001824 80 0.449
regulation of mesenchymal cell apoptotic process involved in metanephros development GO:1900211 4 0.442
Mouse
endothelial cell proliferation GO:0001935 27 0.435
maternal placenta development GO:0001893 20 0.428
mrna 3 end processing GO:0031124 16 0.427
negative regulation of wnt signaling pathway GO:0030178 73 0.415
bone morphogenesis GO:0060349 78 0.411
adrenal cortex formation GO:0035802 2 0.408
Mouse
regulation of cell cycle GO:0051726 281 0.404
developmental maturation GO:0021700 193 0.404
Worm
epidermis development GO:0008544 187 0.402
female gonad development GO:0008585 71 0.401
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.398
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 16 0.396
rhythmic process GO:0048511 174 0.393
Mouse Rat
cognition GO:0050890 149 0.393
Rat
forebrain development GO:0030900 302 0.387
chemotaxis GO:0006935 247 0.385
Mouse
hippocampus development GO:0021766 52 0.376
negative regulation of cellular protein metabolic process GO:0032269 247 0.374
Worm
negative regulation of map kinase activity GO:0043407 34 0.373
Worm
positive regulation of chromatin modification GO:1903310 28 0.369
regulation of neuron death GO:1901214 134 0.367
Rat
nephron development GO:0072006 109 0.365
Mouse Rat
neural tube development GO:0021915 160 0.364
endocrine system development GO:0035270 98 0.363
Mouse
cellular response to extracellular stimulus GO:0031668 81 0.360
regulation of transforming growth factor beta2 production GO:0032909 2 0.360
regulation of neuron projection development GO:0010975 169 0.353
glial cell differentiation GO:0010001 131 0.345
Mouse Rat
amine metabolic process GO:0009308 45 0.343
microglial cell activation GO:0001774 3 0.341
cellular amine metabolic process GO:0044106 44 0.336
negative regulation of phosphate metabolic process GO:0045936 184 0.331
Worm
epithelial cell proliferation GO:0050673 174 0.330
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.326
regulation of protein kinase activity GO:0045859 232 0.321
Worm
compound eye development GO:0048749 1 0.321
epithelial cell differentiation involved in kidney development GO:0035850 23 0.320
Mouse
rhombomere formation GO:0021594 1 0.318
Mouse
associative learning GO:0008306 61 0.317
diencephalon development GO:0021536 63 0.309
sensory system development GO:0048880 3 0.306
cell fate commitment GO:0045165 210 0.305
Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.305
response to extracellular stimulus GO:0009991 127 0.302
Rat
phagocytosis GO:0006909 66 0.302
Fly
synapse organization GO:0050808 125 0.301
development of primary sexual characteristics GO:0045137 143 0.300
Mouse
response to peptide hormone GO:0043434 127 0.298
digestive tract morphogenesis GO:0048546 147 0.293
cellular response to calcium ion GO:0071277 14 0.292
regulation of protein deacetylation GO:0090311 17 0.288
chromatin organization GO:0006325 206 0.288
monosaccharide metabolic process GO:0005996 106 0.288
cellular ketone metabolic process GO:0042180 84 0.288
response to corticosterone GO:0051412 1 0.286
wnt signaling pathway GO:0016055 188 0.286
development of primary female sexual characteristics GO:0046545 73 0.283
Mouse
positive regulation of brown fat cell differentiation GO:0090336 4 0.283
negative regulation of respiratory burst involved in inflammatory response GO:0060266 1 0.280
angiogenesis GO:0001525 201 0.279
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 12 0.279
synaptic transmission GO:0007268 329 0.277
Mouse Rat
positive regulation of reproductive process GO:2000243 19 0.275
Mouse
central nervous system projection neuron axonogenesis GO:0021952 21 0.274
learning or memory GO:0007611 148 0.273
Rat
regulation of blood circulation GO:1903522 93 0.269
cell maturation GO:0048469 127 0.266
Worm
skeletal system morphogenesis GO:0048705 203 0.263
Zebrafish
monocyte differentiation GO:0030224 9 0.261
female gamete generation GO:0007292 74 0.261
Worm
covalent chromatin modification GO:0016569 163 0.261
positive regulation of epithelial cell proliferation GO:0050679 68 0.260
negative regulation of transcription from rna polymerase ii promoter in response to stress GO:0097201 1 0.258
nuclear transcribed mrna poly a tail shortening GO:0000289 7 0.257
canonical wnt signaling pathway GO:0060070 130 0.253
negative regulation of neuron apoptotic process GO:0043524 92 0.252
negative regulation of defense response GO:0031348 77 0.251
positive regulation of neuron differentiation GO:0045666 141 0.248
telencephalon development GO:0021537 186 0.246
regulation of kinase activity GO:0043549 249 0.246
Worm
brown fat cell differentiation GO:0050873 36 0.246
regulation of membrane potential GO:0042391 192 0.243
Mouse
lateral line system development GO:0048925 1 0.240
locomotory behavior GO:0007626 195 0.237
regulation of canonical wnt signaling pathway GO:0060828 82 0.235
spermatogenesis GO:0007283 284 0.234
Mouse
epithelial tube morphogenesis GO:0060562 303 0.234
Mouse
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.232
Mouse
regulation of angiogenesis GO:0045765 81 0.232
epithelial cell development GO:0002064 159 0.231
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.230
body morphogenesis GO:0010171 45 0.228
positive regulation of mrna 3 end processing GO:0031442 5 0.227
renal filtration cell differentiation GO:0061318 10 0.227
Mouse
negative regulation of protein modification process GO:0031400 163 0.226
Worm
regulation of fibroblast proliferation GO:0048145 34 0.226
regulation of cellular amino acid metabolic process GO:0006521 5 0.225
positive regulation of cell development GO:0010720 237 0.223
dendrite development GO:0016358 115 0.222
cell growth GO:0016049 130 0.222
g protein coupled receptor signaling pathway GO:0007186 243 0.217
regulation of mrna 3 end processing GO:0031440 6 0.217
morphogenesis of a branching structure GO:0001763 203 0.215
Mouse
renal tubule development GO:0061326 87 0.214
Mouse
fibroblast proliferation GO:0048144 35 0.213
regulation of histone modification GO:0031056 56 0.212
rhythmic behavior GO:0007622 15 0.210
Mouse
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.209
embryonic process involved in female pregnancy GO:0060136 7 0.207
striated muscle tissue development GO:0014706 293 0.206
positive regulation of histone modification GO:0031058 28 0.205
regulation of bmp signaling pathway GO:0030510 60 0.204
positive regulation of fibroblast proliferation GO:0048146 20 0.202
neuron death GO:0070997 154 0.199
Rat
general adaptation syndrome GO:0051866 2 0.195
sertoli cell differentiation GO:0060008 18 0.193
Mouse
positive regulation of growth GO:0045927 104 0.189
Mouse
male gamete generation GO:0048232 285 0.189
Mouse
response to amphetamine GO:0001975 16 0.188
Rat
cellular response to external stimulus GO:0071496 88 0.185
Rat
germ cell development GO:0007281 185 0.184
Mouse Worm
regulation of chromatin modification GO:1903308 57 0.184
bmp signaling pathway GO:0030509 93 0.183
regulation of metanephric ureteric bud development GO:2001074 1 0.181
Mouse
regulation of myeloid leukocyte differentiation GO:0002761 58 0.179
cellular response to dna damage stimulus GO:0006974 207 0.179
bone development GO:0060348 120 0.177
regulation of respiratory burst GO:0060263 2 0.176
cellular response to growth factor stimulus GO:0071363 197 0.175
Rat
multicellular organism growth GO:0035264 161 0.173
transcription from rna polymerase iii promoter GO:0006383 3 0.170
gluconeogenesis GO:0006094 39 0.170
labyrinthine layer blood vessel development GO:0060716 21 0.167
schwann cell differentiation GO:0014037 26 0.167
Mouse
hexose metabolic process GO:0019318 98 0.165
t cell differentiation in thymus GO:0033077 77 0.164
Mouse
positive regulation of cellular catabolic process GO:0031331 148 0.164
glomerular mesangial cell proliferation GO:0072110 3 0.163
Mouse Rat
rhombomere 3 morphogenesis GO:0021658 2 0.163
Mouse
limbic system development GO:0021761 72 0.162
metanephric part of ureteric bud development GO:0035502 2 0.159
Mouse
formation of primary germ layer GO:0001704 77 0.159
cell type specific apoptotic process GO:0097285 268 0.159
Mouse Rat
rhombomere morphogenesis GO:0021593 2 0.157
Mouse
chromatin modification GO:0016568 187 0.157
cellular response to peptide GO:1901653 92 0.157
Rat
rna processing GO:0006396 105 0.157
Mouse
learning GO:0007612 98 0.156
regulation of reproductive process GO:2000241 66 0.155
Mouse Worm
protein deacylation GO:0035601 36 0.154
locomotor rhythm GO:0045475 8 0.151
endocytosis GO:0006897 168 0.150
Fly
digestive tract development GO:0048565 190 0.148
ameboidal type cell migration GO:0001667 128 0.147
Fly
macromolecule methylation GO:0043414 120 0.147
cellular macromolecule catabolic process GO:0044265 206 0.147
response to oxygen levels GO:0070482 62 0.146
action potential GO:0001508 78 0.144
Mouse
positive regulation of myeloid cell differentiation GO:0045639 43 0.144
muscle cell differentiation GO:0042692 261 0.144
Mouse
trophectodermal cell differentiation GO:0001829 21 0.142
response to inorganic substance GO:0010035 96 0.141
epithalamus development GO:0021538 2 0.140
kidney morphogenesis GO:0060993 83 0.140
Mouse
response to mineralocorticoid GO:0051385 1 0.139
cellular response to oxidative stress GO:0034599 76 0.139
regulation of inflammatory response GO:0050727 147 0.139
protein modification by small protein conjugation or removal GO:0070647 207 0.139
Human
sprouting angiogenesis GO:0002040 26 0.138
regionalization GO:0003002 337 0.137
Mouse
negative regulation of phosphorus metabolic process GO:0010563 184 0.136
Worm
regulation of endothelial cell proliferation GO:0001936 23 0.136
negative regulation of organ growth GO:0046621 17 0.136
response to metal ion GO:0010038 47 0.134
regulation of chromatin organization GO:1902275 57 0.134
liver development GO:0001889 66 0.133
stem cell differentiation GO:0048863 268 0.133
heart growth GO:0060419 45 0.132
Mouse
regulation of cytokine production GO:0001817 266 0.132
regulation of myeloid cell differentiation GO:0045637 96 0.132
positive regulation of protein modification process GO:0031401 299 0.131
regulation of mrna metabolic process GO:1903311 43 0.131
mesoderm morphogenesis GO:0048332 64 0.129
regulation of transferase activity GO:0051338 263 0.129
Worm
neuron projection guidance GO:0097485 141 0.129
Mouse
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.129
gene silencing by mirna GO:0035195 10 0.128
posterior mesonephric tubule development GO:0072166 2 0.127
Mouse
mitotic cell cycle GO:0000278 195 0.127
vestibular reflex GO:0060005 4 0.127
carbohydrate metabolic process GO:0005975 230 0.126
gliogenesis GO:0042063 141 0.125
Mouse Rat
response to decreased oxygen levels GO:0036293 59 0.125
sertoli cell development GO:0060009 15 0.125
Mouse
regulation of nucleotide metabolic process GO:0006140 169 0.125
regulation of mrna catabolic process GO:0061013 6 0.125
osteoblast development GO:0002076 17 0.124
central nervous system neuron differentiation GO:0021953 162 0.124
multi multicellular organism process GO:0044706 109 0.121
conditioned taste aversion GO:0001661 4 0.121
metanephric s shaped body morphogenesis GO:0072284 2 0.121
Mouse
blastocyst formation GO:0001825 33 0.120
regulation of nuclear transcribed mrna poly a tail shortening GO:0060211 4 0.119
heterocycle catabolic process GO:0046700 280 0.118
maternal process involved in female pregnancy GO:0060135 32 0.118
histone modification GO:0016570 159 0.118
nephron tubule morphogenesis GO:0072078 68 0.118
Mouse
oocyte maturation GO:0001556 18 0.117
Worm
central nervous system neuron axonogenesis GO:0021955 28 0.116
circadian behavior GO:0048512 13 0.115
glomerular visceral epithelial cell differentiation GO:0072112 10 0.114
Mouse
regulation of osteoblast differentiation GO:0045667 67 0.113
adipose tissue development GO:0060612 25 0.113
regulation of epithelial cell proliferation GO:0050678 141 0.112
glucose metabolic process GO:0006006 92 0.111
purine containing compound metabolic process GO:0072521 311 0.110
hindbrain development GO:0030902 128 0.110
Mouse
mesonephric tubule development GO:0072164 94 0.109
Mouse
male gonad development GO:0008584 88 0.109
Mouse
regulation of neuronal synaptic plasticity GO:0048168 30 0.109
Rat
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 8 0.108
regulation of t cell differentiation in thymus GO:0033081 24 0.105
Mouse
nephron epithelium development GO:0072009 92 0.103
Mouse
embryonic viscerocranium morphogenesis GO:0048703 8 0.103
Zebrafish
oligodendrocyte differentiation GO:0048709 53 0.103
Rat
regulation of cellular response to stress GO:0080135 159 0.103
ossification GO:0001503 216 0.102
Mouse
urogenital system development GO:0001655 261 0.101
Mouse Rat
somatic stem cell maintenance GO:0035019 47 0.101
positive regulation of blood circulation GO:1903524 22 0.101
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902043 13 0.101
circadian rhythm GO:0007623 114 0.099
Rat
lipid biosynthetic process GO:0008610 179 0.099
response to drug GO:0042493 75 0.099
Rat
negative regulation of protein phosphorylation GO:0001933 126 0.098
Worm
embryonic placenta morphogenesis GO:0060669 25 0.098
mesoderm development GO:0007498 100 0.098
inflammatory response GO:0006954 244 0.097
negative regulation of intracellular signal transduction GO:1902532 167 0.096
Worm
fibroblast growth factor production GO:0090269 4 0.096
positive regulation of t cell differentiation GO:0045582 52 0.095
Mouse
adrenal gland development GO:0030325 18 0.095
Mouse
protein deacetylation GO:0006476 32 0.095
pole plasm assembly GO:0007315 2 0.095
cell differentiation involved in kidney development GO:0061005 33 0.094
Mouse
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.094
regulation of system process GO:0044057 200 0.094
skin development GO:0043588 220 0.094
oocyte differentiation GO:0009994 35 0.093
Worm
synapse assembly GO:0007416 56 0.092
cellular amino acid metabolic process GO:0006520 103 0.091
cellular response to peptide hormone stimulus GO:0071375 92 0.091
Rat
heart morphogenesis GO:0003007 178 0.090
ribose phosphate metabolic process GO:0019693 291 0.090
response to transforming growth factor beta GO:0071559 88 0.090
response to alcohol GO:0097305 48 0.089
Rat
labyrinthine layer morphogenesis GO:0060713 21 0.089
regulation of antimicrobial humoral response GO:0002759 3 0.089
myelination GO:0042552 74 0.088
Mouse
cell migration involved in sprouting angiogenesis GO:0002042 9 0.088
monocarboxylic acid metabolic process GO:0032787 191 0.088
gastrulation GO:0007369 116 0.088
developmental cell growth GO:0048588 84 0.087
negative regulation of immune system process GO:0002683 209 0.086
epithelial cell migration GO:0010631 63 0.085
Fly
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 3 0.085
regulation of mapk cascade GO:0043408 248 0.084
Worm
regulation of map kinase activity GO:0043405 120 0.083
Worm
response to radiation GO:0009314 165 0.083
regulation of cellular catabolic process GO:0031329 242 0.082
negative regulation of neuron projection development GO:0010977 50 0.082
negative regulation of kinase activity GO:0033673 81 0.082
Worm
cellular response to starvation GO:0009267 57 0.081
negative regulation of cellular amine metabolic process GO:0033239 1 0.081
cardiac muscle hypertrophy in response to stress GO:0014898 10 0.081
response to lipopolysaccharide GO:0032496 128 0.081
cellular response to hypoxia GO:0071456 17 0.080
circulatory system process GO:0003013 197 0.079
macrophage activation GO:0042116 27 0.079
metanephric glomerulus development GO:0072224 13 0.078
Mouse Rat
positive regulation of chromosome organization GO:2001252 33 0.078
response to hypoxia GO:0001666 58 0.078
positive regulation of angiogenesis GO:0045766 46 0.078
ureteric bud development GO:0001657 94 0.078
Mouse
muscle cell proliferation GO:0033002 52 0.078
mesonephric epithelium development GO:0072163 94 0.078
Mouse
layer formation in cerebral cortex GO:0021819 13 0.077
wound healing GO:0042060 157 0.077
apoptotic process involved in development GO:1902742 28 0.077
Mouse
regulation of translation GO:0006417 71 0.077
negative regulation of proteolysis GO:0045861 74 0.077
stem cell development GO:0048864 219 0.076
facial nerve structural organization GO:0021612 10 0.076
Mouse
regulation of cell migration involved in sprouting angiogenesis GO:0090049 4 0.076
regulation of t cell differentiation GO:0045580 83 0.076
Mouse
response to organic cyclic compound GO:0014070 198 0.076
Rat
rap protein signal transduction GO:0032486 3 0.076
regulation of cell migration GO:0030334 219 0.075
branching morphogenesis of an epithelial tube GO:0048754 159 0.075
Mouse
negative regulation of neuron projection regeneration GO:0070571 3 0.075
cellular response to lipid GO:0071396 145 0.075
Rat
nucleobase containing small molecule metabolic process GO:0055086 352 0.074
regulation of multi organism process GO:0043900 111 0.074
Worm
adult behavior GO:0030534 135 0.074
multicellular organismal signaling GO:0035637 91 0.074
Mouse
cellular lipid metabolic process GO:0044255 323 0.073
regulation of organ morphogenesis GO:2000027 144 0.073
Mouse
negative regulation of tyrosine phosphorylation of stat protein GO:0042532 3 0.073
positive regulation of endothelial cell proliferation GO:0001938 17 0.072
response to purine containing compound GO:0014074 28 0.072
Rat
ovulation cycle GO:0042698 59 0.072
immune effector process GO:0002252 321 0.072
response to calcium ion GO:0051592 20 0.072
regulation of histone deacetylation GO:0031063 12 0.071
cellular response to hormone stimulus GO:0032870 150 0.071
Rat
posttranscriptional gene silencing by rna GO:0035194 10 0.071
mesoderm formation GO:0001707 62 0.071
regulation of cellular ketone metabolic process GO:0010565 66 0.070
embryonic skeletal system development GO:0048706 120 0.070
Zebrafish
gonad development GO:0008406 141 0.070
Mouse
regulation of glomerular mesangial cell proliferation GO:0072124 1 0.069
Mouse Rat
regulation of cell motility GO:2000145 236 0.068
regulation of metanephric glomerular mesangial cell proliferation GO:0072301 1 0.068
Mouse Rat
i kappab kinase nf kappab signaling GO:0007249 85 0.068
cellular response to metal ion GO:0071248 31 0.068
regulation of gamma delta t cell activation GO:0046643 9 0.067
Mouse
oxidation reduction process GO:0055114 342 0.067
phenol containing compound biosynthetic process GO:0046189 21 0.067
epithelial cell morphogenesis GO:0003382 41 0.067
Mouse
humoral immune response GO:0006959 57 0.067
cellular response to oxygen levels GO:0071453 20 0.067
endothelial cell migration GO:0043542 44 0.066
glomerular epithelial cell development GO:0072310 6 0.066
Mouse
viral gene expression GO:0019080 3 0.066
embryonic hemopoiesis GO:0035162 23 0.066
segmentation GO:0035282 93 0.066
Mouse
response to nutrient levels GO:0031667 109 0.066
Rat
regulation of binding GO:0051098 111 0.066
metanephric glomerular mesangial cell proliferation involved in metanephros development GO:0072262 3 0.066
Mouse Rat
protein targeting GO:0006605 143 0.065
peripheral nervous system development GO:0007422 53 0.065
Mouse
glucose homeostasis GO:0042593 128 0.065
organonitrogen compound biosynthetic process GO:1901566 192 0.065
cranial nerve structural organization GO:0021604 13 0.065
Mouse
regulation of organ growth GO:0046620 61 0.064
Mouse
negative regulation of neuron differentiation GO:0045665 101 0.064
skeletal system development GO:0001501 356 0.064
Zebrafish
negative regulation of nervous system development GO:0051961 156 0.064
positive regulation of muscle contraction GO:0045933 10 0.063
tissue migration GO:0090130 68 0.063
Fly
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.063
regulation of hydrolase activity GO:0051336 246 0.063
regulation of response to wounding GO:1903034 189 0.062
axon ensheathment GO:0008366 76 0.062
Mouse
ribonucleotide biosynthetic process GO:0009260 59 0.062
embryonic organ morphogenesis GO:0048562 276 0.062
Zebrafish
adult locomotory behavior GO:0008344 91 0.062
cd4 positive alpha beta t cell activation GO:0035710 45 0.062
cardiac muscle tissue development GO:0048738 130 0.062
Mouse
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.062
positive regulation of intracellular steroid hormone receptor signaling pathway GO:0033145 4 0.062
lung development GO:0030324 164 0.062
midgut development GO:0007494 4 0.062
muscle system process GO:0003012 141 0.061
macromolecule deacylation GO:0098732 37 0.061
hexose biosynthetic process GO:0019319 39 0.061
lymphocyte differentiation GO:0030098 242 0.061
peripheral nervous system neuron axonogenesis GO:0048936 3 0.061
ovarian follicle development GO:0001541 40 0.060
regulation of activation of jak2 kinase activity GO:0010534 1 0.060
regulation of peptidase activity GO:0052547 96 0.060
positive regulation of organelle organization GO:0010638 128 0.060
blood circulation GO:0008015 195 0.059
negative regulation of epithelial cell proliferation GO:0050680 64 0.059
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.059
protein export from nucleus GO:0006611 20 0.059
Mouse
response to insulin GO:0032868 100 0.058
synaptic growth at neuromuscular junction GO:0051124 6 0.058
t cell differentiation GO:0030217 174 0.058
negative regulation of hydrolase activity GO:0051346 71 0.058
positive regulation of nervous system development GO:0051962 221 0.058
cardiac chamber morphogenesis GO:0003206 93 0.058
cellular response to radiation GO:0071478 28 0.057
rhombomere 3 development GO:0021569 4 0.057
Mouse
smad protein signal transduction GO:0060395 21 0.057
single fertilization GO:0007338 82 0.057
Mouse
positive regulation of cytokine production GO:0001819 174 0.057
response to camp GO:0051591 14 0.057
Rat
regulation of cell projection organization GO:0031344 206 0.057
response to molecule of bacterial origin GO:0002237 143 0.056
response to reactive oxygen species GO:0000302 56 0.056
kidney vasculature development GO:0061440 15 0.056
Mouse Rat
response to oxidative stress GO:0006979 123 0.056
purine nucleotide metabolic process GO:0006163 302 0.056
camera type eye development GO:0043010 266 0.056
Zebrafish Mouse
mechanoreceptor differentiation GO:0042490 67 0.056
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.056
female sex differentiation GO:0046660 84 0.055
Mouse
regulation of heart growth GO:0060420 31 0.054
Mouse
positive regulation of camp metabolic process GO:0030816 19 0.054
positive regulation of neuron apoptotic process GO:0043525 25 0.054
Rat
glycosyl compound metabolic process GO:1901657 246 0.054
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.053
developmental growth involved in morphogenesis GO:0060560 138 0.053
male sex differentiation GO:0046661 109 0.053
Mouse
rna catabolic process GO:0006401 29 0.053
motor neuron axon guidance GO:0008045 26 0.053
Mouse
regulation of glomerulus development GO:0090192 6 0.052
Mouse Rat
inner ear morphogenesis GO:0042472 101 0.052
positive regulation of nucleotide metabolic process GO:0045981 114 0.052
chorio allantoic fusion GO:0060710 8 0.052
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.052
habenula development GO:0021986 2 0.051
regulation of activation of janus kinase activity GO:0010533 1 0.051

Egr1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.242
disease of cellular proliferation DOID:14566 0 0.242
neuromuscular disease DOID:440 0 0.159
disease of anatomical entity DOID:7 0 0.159
charcot marie tooth disease DOID:10595 0 0.159
nervous system disease DOID:863 0 0.159
neuropathy DOID:870 0 0.159
organ system cancer DOID:0050686 0 0.126