Mus musculus

2 known processes

Esd

esterase D/formylglutathione hydrolase

(Aliases: Es-10,sid478,Es10)

Esd biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.132
protein maturation GO:0051604 176 0.076
oxidation reduction process GO:0055114 342 0.067
amine metabolic process GO:0009308 45 0.061
apoptotic signaling pathway GO:0097190 306 0.061
regulation of hydrolase activity GO:0051336 246 0.060
l ascorbic acid metabolic process GO:0019852 4 0.059
cellular response to dna damage stimulus GO:0006974 207 0.059
negative regulation of molecular function GO:0044092 258 0.055
ion transmembrane transport GO:0034220 361 0.054
response to oxidative stress GO:0006979 123 0.053
regulation of apoptotic signaling pathway GO:2001233 197 0.051
transmembrane transport GO:0055085 412 0.049
cation homeostasis GO:0055080 212 0.048
cellular homeostasis GO:0019725 240 0.047
regulation of cellular amino acid metabolic process GO:0006521 5 0.044
male gamete generation GO:0048232 285 0.043
protein processing GO:0016485 163 0.043
hexose catabolic process GO:0019320 3 0.043
response to oxygen radical GO:0000305 16 0.039
intracellular protein transport GO:0006886 204 0.039
cellular amine metabolic process GO:0044106 44 0.039
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.039
heterocycle catabolic process GO:0046700 280 0.039
nucleotide catabolic process GO:0009166 217 0.039
monocarboxylic acid metabolic process GO:0032787 191 0.038
cellular ketone metabolic process GO:0042180 84 0.036
protein localization to organelle GO:0033365 185 0.036
regulation of cellular response to stress GO:0080135 159 0.035
nucleotide metabolic process GO:0009117 332 0.035
immune effector process GO:0002252 321 0.034
reactive oxygen species metabolic process GO:0072593 84 0.034
spermatogenesis GO:0007283 284 0.034
regulation of response to wounding GO:1903034 189 0.034
cellular divalent inorganic cation homeostasis GO:0072503 127 0.034
regulation of membrane potential GO:0042391 192 0.033
nucleobase containing small molecule metabolic process GO:0055086 352 0.033
myeloid cell differentiation GO:0030099 233 0.033
cellular modified amino acid metabolic process GO:0006575 63 0.033
regulation of transferase activity GO:0051338 263 0.032
organonitrogen compound catabolic process GO:1901565 264 0.032
maintenance of location GO:0051235 89 0.032
positive regulation of apoptotic process GO:0043065 217 0.032
positive regulation of proteolysis GO:0045862 85 0.032
regulation of peptidase activity GO:0052547 96 0.032
glycosyl compound metabolic process GO:1901657 246 0.031
metal ion homeostasis GO:0055065 189 0.031
apoptotic mitochondrial changes GO:0008637 48 0.031
cation transport GO:0006812 399 0.031
ribonucleotide metabolic process GO:0009259 291 0.031
response to reactive oxygen species GO:0000302 56 0.031
cellular ion homeostasis GO:0006873 165 0.031
regulation of cellular amine metabolic process GO:0033238 20 0.031
response to organonitrogen compound GO:0010243 246 0.031
water soluble vitamin biosynthetic process GO:0042364 3 0.031
organic hydroxy compound metabolic process GO:1901615 203 0.030
cellular response to lipid GO:0071396 145 0.030
regulation of kinase activity GO:0043549 249 0.030
peptide transport GO:0015833 133 0.030
regulation of proteolysis GO:0030162 164 0.030
i kappab kinase nf kappab signaling GO:0007249 85 0.030
cellular chemical homeostasis GO:0055082 215 0.029
cytoplasmic transport GO:0016482 234 0.029
gonad development GO:0008406 141 0.029
mapk cascade GO:0000165 281 0.029
nucleoside phosphate metabolic process GO:0006753 338 0.029
negative regulation of protein metabolic process GO:0051248 282 0.029
macromolecule catabolic process GO:0009057 281 0.028
positive regulation of cellular amine metabolic process GO:0033240 5 0.028
carbohydrate derivative biosynthetic process GO:1901137 183 0.028
ubiquitin dependent protein catabolic process GO:0006511 129 0.028
response to inorganic substance GO:0010035 96 0.028
anion transport GO:0006820 177 0.028
purine ribonucleoside metabolic process GO:0046128 241 0.027
protein catabolic process GO:0030163 221 0.027
regulation of ion transport GO:0043269 215 0.027
positive regulation of protein modification process GO:0031401 299 0.027
sequestering of metal ion GO:0051238 19 0.027
cellular metal ion homeostasis GO:0006875 151 0.027
response to acid chemical GO:0001101 111 0.027
alpha amino acid metabolic process GO:1901605 59 0.026
sulfur compound metabolic process GO:0006790 100 0.026
positive regulation of cell death GO:0010942 224 0.026
dna metabolic process GO:0006259 303 0.026
regulation of protein localization GO:0032880 231 0.026
positive regulation of peptidase activity GO:0010952 49 0.026
purine ribonucleoside catabolic process GO:0046130 205 0.026
cellular lipid metabolic process GO:0044255 323 0.025
inflammatory response GO:0006954 244 0.025
ribonucleoside metabolic process GO:0009119 245 0.025
organic cyclic compound catabolic process GO:1901361 295 0.025
regulation of protein kinase activity GO:0045859 232 0.025
aromatic compound catabolic process GO:0019439 286 0.025
cellular macromolecule catabolic process GO:0044265 206 0.025
purine nucleoside metabolic process GO:0042278 241 0.025
nucleoside triphosphate metabolic process GO:0009141 230 0.025
cellular protein complex assembly GO:0043623 116 0.025
sensory perception GO:0007600 245 0.024
regulation of cellular catabolic process GO:0031329 242 0.024
nucleoside phosphate catabolic process GO:1901292 222 0.024
regulation of endopeptidase activity GO:0052548 89 0.024
nitrogen compound transport GO:0071705 271 0.024
amide transport GO:0042886 138 0.024
extracellular structure organization GO:0043062 148 0.024
purine ribonucleotide catabolic process GO:0009154 208 0.024
regulation of reactive oxygen species metabolic process GO:2000377 40 0.024
organonitrogen compound biosynthetic process GO:1901566 192 0.023
membrane organization GO:0061024 245 0.023
organophosphate catabolic process GO:0046434 232 0.023
modification dependent protein catabolic process GO:0019941 133 0.023
purine nucleoside catabolic process GO:0006152 205 0.023
cellular protein catabolic process GO:0044257 155 0.023
regulation of organelle organization GO:0033043 289 0.023
carbohydrate derivative catabolic process GO:1901136 231 0.023
response to lipopolysaccharide GO:0032496 128 0.023
nucleoside metabolic process GO:0009116 246 0.022
innate immune response GO:0045087 157 0.022
ribose phosphate metabolic process GO:0019693 291 0.022
cellular nitrogen compound catabolic process GO:0044270 280 0.022
cellular calcium ion homeostasis GO:0006874 119 0.022
regulation of mapk cascade GO:0043408 248 0.022
circulatory system process GO:0003013 197 0.022
positive regulation of hydrolase activity GO:0051345 148 0.022
regulation of protein import into nucleus GO:0042306 52 0.022
positive regulation of programmed cell death GO:0043068 218 0.021
response to molecule of bacterial origin GO:0002237 143 0.021
organic anion transport GO:0015711 137 0.021
regulation of protein serine threonine kinase activity GO:0071900 157 0.021
ribonucleotide catabolic process GO:0009261 208 0.021
negative regulation of cell proliferation GO:0008285 296 0.020
cellular response to lipopolysaccharide GO:0071222 77 0.020
regulation of cellular ketone metabolic process GO:0010565 66 0.020
negative regulation of cellular protein metabolic process GO:0032269 247 0.020
positive regulation of kinase activity GO:0033674 155 0.020
calcium ion homeostasis GO:0055074 127 0.020
glutathione metabolic process GO:0006749 16 0.020
purine containing compound metabolic process GO:0072521 311 0.020
positive regulation of protein phosphorylation GO:0001934 242 0.020
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.020
negative regulation of immune system process GO:0002683 209 0.020
response to extracellular stimulus GO:0009991 127 0.020
carbohydrate metabolic process GO:0005975 230 0.020
purine nucleotide catabolic process GO:0006195 211 0.020
regulation of intracellular transport GO:0032386 159 0.020
regulation of hormone levels GO:0010817 211 0.019
response to organic cyclic compound GO:0014070 198 0.019
homeostasis of number of cells GO:0048872 210 0.019
cation transmembrane transport GO:0098655 266 0.019
sequestering of calcium ion GO:0051208 18 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.019
multi multicellular organism process GO:0044706 109 0.019
purine ribonucleotide metabolic process GO:0009150 290 0.019
cellular response to oxidative stress GO:0034599 76 0.019
cell type specific apoptotic process GO:0097285 268 0.019
superoxide metabolic process GO:0006801 27 0.019
protein targeting GO:0006605 143 0.019
t cell differentiation GO:0030217 174 0.019
regulation of cysteine type endopeptidase activity GO:2000116 65 0.018
carboxylic acid biosynthetic process GO:0046394 86 0.018
negative regulation of phosphorylation GO:0042326 166 0.018
negative regulation of phosphate metabolic process GO:0045936 184 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.018
inorganic cation transmembrane transport GO:0098662 207 0.018
protein localization to nucleus GO:0034504 121 0.018
wound healing GO:0042060 157 0.018
positive regulation of response to wounding GO:1903036 66 0.018
protein import GO:0017038 101 0.018
peptide metabolic process GO:0006518 46 0.018
lymphocyte proliferation GO:0046651 164 0.018
mitochondrion organization GO:0007005 134 0.018
negative regulation of apoptotic signaling pathway GO:2001234 104 0.018
proteasomal protein catabolic process GO:0010498 98 0.018
regulation of transcription factor import into nucleus GO:0042990 24 0.018
regulation of lymphocyte activation GO:0051249 240 0.017
divalent metal ion transport GO:0070838 172 0.017
placenta development GO:0001890 140 0.017
regulation of body fluid levels GO:0050878 162 0.017
microtubule based process GO:0007017 236 0.017
endomembrane system organization GO:0010256 147 0.017
negative regulation of cellular component organization GO:0051129 194 0.017
purine containing compound catabolic process GO:0072523 213 0.017
coagulation GO:0050817 78 0.017
engulfment of apoptotic cell GO:0043652 3 0.016
nuclear import GO:0051170 95 0.016
leukocyte proliferation GO:0070661 172 0.016
establishment of protein localization to organelle GO:0072594 118 0.016
positive regulation of endopeptidase activity GO:0010950 43 0.016
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.016
glycosyl compound catabolic process GO:1901658 206 0.016
peptidyl amino acid modification GO:0018193 336 0.016
regulation of ion transmembrane transport GO:0034765 119 0.016
4 hydroxyproline metabolic process GO:0019471 5 0.016
retrograde transport endosome to golgi GO:0042147 2 0.016
regulation of cell activation GO:0050865 289 0.016
negative regulation of lymphocyte activation GO:0051250 91 0.016
regulation of anatomical structure size GO:0090066 178 0.016
lymphocyte differentiation GO:0030098 242 0.016
angiogenesis GO:0001525 201 0.016
regulation of protein transport GO:0051223 163 0.016
regulation of t cell activation GO:0050863 170 0.016
single organism nuclear import GO:1902593 95 0.016
extracellular matrix organization GO:0030198 147 0.016
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.016
cellular response to extracellular stimulus GO:0031668 81 0.016
positive regulation of transferase activity GO:0051347 167 0.016
modification dependent macromolecule catabolic process GO:0043632 133 0.016
ribonucleoside catabolic process GO:0042454 206 0.016
regulation of protein targeting GO:1903533 61 0.016
glucose homeostasis GO:0042593 128 0.016
leukocyte mediated immunity GO:0002443 174 0.016
ribonucleoside triphosphate metabolic process GO:0009199 220 0.016
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.016
forebrain development GO:0030900 302 0.016
oocyte axis specification GO:0007309 2 0.015
blood circulation GO:0008015 195 0.015
gland development GO:0048732 330 0.015
nuclear transport GO:0051169 139 0.015
purine nucleoside triphosphate metabolic process GO:0009144 226 0.015
regulation of secretion GO:0051046 274 0.015
positive regulation of organelle organization GO:0010638 128 0.015
cofactor metabolic process GO:0051186 80 0.015
negative regulation of t cell activation GO:0050868 65 0.015
t cell activation GO:0042110 289 0.015
response to monosaccharide GO:0034284 67 0.015
regulation of transmembrane transport GO:0034762 128 0.015
development of primary sexual characteristics GO:0045137 143 0.015
nucleoside catabolic process GO:0009164 206 0.015
synaptic transmission GO:0007268 329 0.015
negative regulation of cell activation GO:0050866 111 0.015
regulation of coagulation GO:0050818 31 0.015
response to metal ion GO:0010038 47 0.015
regulation of system process GO:0044057 200 0.015
organelle fission GO:0048285 170 0.015
cellular response to biotic stimulus GO:0071216 92 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
guanosine containing compound metabolic process GO:1901068 144 0.015
muscle cell differentiation GO:0042692 261 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.015
calcium ion transport GO:0006816 159 0.015
small gtpase mediated signal transduction GO:0007264 97 0.015
regulation of homeostatic process GO:0032844 182 0.014
locomotory behavior GO:0007626 195 0.014
protein localization to membrane GO:0072657 108 0.014
regulation of map kinase activity GO:0043405 120 0.014
purine nucleotide metabolic process GO:0006163 302 0.014
regulation of cytoplasmic transport GO:1903649 112 0.014
blood vessel morphogenesis GO:0048514 285 0.014
divalent inorganic cation homeostasis GO:0072507 138 0.014
extrinsic apoptotic signaling pathway GO:0097191 126 0.014
regulation of multi organism process GO:0043900 111 0.014
stress activated mapk cascade GO:0051403 80 0.014
regulation of establishment of protein localization GO:0070201 181 0.014
organelle assembly GO:0070925 177 0.014
g protein coupled receptor signaling pathway GO:0007186 243 0.014
skeletal system development GO:0001501 356 0.014
myeloid cell homeostasis GO:0002262 114 0.014
t cell proliferation GO:0042098 120 0.014
purine nucleoside triphosphate catabolic process GO:0009146 203 0.014
tissue homeostasis GO:0001894 115 0.014
stress activated protein kinase signaling cascade GO:0031098 81 0.014
muscle system process GO:0003012 141 0.014
epithelial tube morphogenesis GO:0060562 303 0.014
neuron death GO:0070997 154 0.013
cellular response to molecule of bacterial origin GO:0071219 83 0.013
inorganic ion transmembrane transport GO:0098660 234 0.013
positive regulation of growth GO:0045927 104 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
nucleocytoplasmic transport GO:0006913 139 0.013
cytokine production GO:0001816 319 0.013
regulation of leukocyte differentiation GO:1902105 159 0.013
protein modification by small protein conjugation or removal GO:0070647 207 0.013
myeloid leukocyte differentiation GO:0002573 119 0.013
response to superoxide GO:0000303 16 0.013
hormone metabolic process GO:0042445 86 0.013
nucleoside triphosphate catabolic process GO:0009143 205 0.013
organic acid transport GO:0015849 101 0.013
divalent inorganic cation transport GO:0072511 178 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.012
mitotic cytokinesis GO:0000281 4 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.012
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.012
meiotic cell cycle GO:0051321 122 0.012
male sex differentiation GO:0046661 109 0.012
regulation of defense response GO:0031347 233 0.012
small molecule biosynthetic process GO:0044283 132 0.012
regulation of mitochondrion organization GO:0010821 27 0.012
removal of superoxide radicals GO:0019430 12 0.012
striated muscle myosin thick filament assembly GO:0071688 1 0.012
carbohydrate homeostasis GO:0033500 128 0.012
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.012
negative regulation of protein modification process GO:0031400 163 0.012
lymphocyte mediated immunity GO:0002449 139 0.012
nucleoside monophosphate catabolic process GO:0009125 59 0.012
blood coagulation GO:0007596 76 0.012
regulation of ion transmembrane transporter activity GO:0032412 54 0.012
regulation of secretion by cell GO:1903530 249 0.012
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.012
cell substrate adhesion GO:0031589 130 0.012
leukocyte mediated cytotoxicity GO:0001909 62 0.012
transcription factor import into nucleus GO:0042991 26 0.012
regulation of protein maturation GO:1903317 96 0.012
development of primary male sexual characteristics GO:0046546 88 0.012
wnt signaling pathway GO:0016055 188 0.012
protein import into nucleus GO:0006606 95 0.012
neural tube development GO:0021915 160 0.012
regulation of nucleocytoplasmic transport GO:0046822 73 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.011
protein ubiquitination GO:0016567 171 0.011
ribonucleoside monophosphate metabolic process GO:0009161 80 0.011
ossification GO:0001503 216 0.011
regulation of cytoskeleton organization GO:0051493 122 0.011
anatomical structure homeostasis GO:0060249 145 0.011
asymmetric stem cell division GO:0098722 3 0.011
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.011
negative regulation of transferase activity GO:0051348 85 0.011
regulation of protein catabolic process GO:0042176 108 0.011
cellular amide metabolic process GO:0043603 58 0.011
cellular response to hormone stimulus GO:0032870 150 0.011
positive regulation of map kinase activity GO:0043406 84 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
water soluble vitamin metabolic process GO:0006767 10 0.011
actin polymerization or depolymerization GO:0008154 54 0.011
lateral inhibition GO:0046331 1 0.011
smoothened signaling pathway GO:0007224 105 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
defense response to other organism GO:0098542 197 0.011
rhythmic process GO:0048511 174 0.011
positive regulation of cellular catabolic process GO:0031331 148 0.011
regulation of lymphocyte differentiation GO:0045619 107 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.011
adult behavior GO:0030534 135 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
signal transduction in absence of ligand GO:0038034 55 0.011
response to oxygen levels GO:0070482 62 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
regulation of cytokine production GO:0001817 266 0.011
male gonad development GO:0008584 88 0.011
positive regulation of secretion GO:0051047 130 0.011
exocytosis GO:0006887 121 0.011
regulation of binding GO:0051098 111 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
steroid metabolic process GO:0008202 119 0.011
methylation GO:0032259 134 0.011
muscle contraction GO:0006936 101 0.010
regulation of metal ion transport GO:0010959 106 0.010
leukocyte differentiation GO:0002521 342 0.010
pyridine nucleotide biosynthetic process GO:0019363 4 0.010
organophosphate biosynthetic process GO:0090407 122 0.010
regulation of cell cycle GO:0051726 281 0.010
regulation of t cell differentiation GO:0045580 83 0.010
cytosolic calcium ion homeostasis GO:0051480 70 0.010
cellular response to organonitrogen compound GO:0071417 145 0.010
negative regulation of protein phosphorylation GO:0001933 126 0.010
lipid transport GO:0006869 98 0.010
multicellular organismal signaling GO:0035637 91 0.010
regulation of protein localization to nucleus GO:1900180 60 0.010
atp metabolic process GO:0046034 75 0.010
regulation of cellular component size GO:0032535 121 0.010
negative regulation of proteolysis GO:0045861 74 0.010
small molecule catabolic process GO:0044282 71 0.010
positive regulation of secretion by cell GO:1903532 114 0.010
positive regulation of apoptotic signaling pathway GO:2001235 95 0.010
response to nutrient levels GO:0031667 109 0.010
sensory organ morphogenesis GO:0090596 242 0.010
regulation of immunological synapse formation GO:2000520 2 0.010
cellular response to acid chemical GO:0071229 68 0.010
positive regulation of protein kinase activity GO:0045860 144 0.010

Esd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.030
disease of metabolism DOID:0014667 0 0.028
inherited metabolic disorder DOID:655 0 0.028
central nervous system disease DOID:331 0 0.014
musculoskeletal system disease DOID:17 0 0.013
connective tissue disease DOID:65 0 0.013
immune system disease DOID:2914 0 0.013
brain disease DOID:936 0 0.011
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011