Mus musculus

218 known processes

Gpc3

glypican 3

(Aliases: OCI-5)

Gpc3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
embryonic limb morphogenesis GO:0030326 126 0.974
urogenital system development GO:0001655 261 0.966
non canonical wnt signaling pathway GO:0035567 33 0.963
cartilage development GO:0051216 140 0.953
renal system development GO:0072001 225 0.942
retinal blood vessel morphogenesis GO:0061304 3 0.936
mesenchymal cell differentiation GO:0048762 107 0.917
nephron development GO:0072006 109 0.910
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.907
kidney development GO:0001822 213 0.893
epithelial tube morphogenesis GO:0060562 303 0.888
regulation of epithelial cell proliferation GO:0050678 141 0.886
regulation of bmp signaling pathway GO:0030510 60 0.885
bmp signaling pathway GO:0030509 93 0.878
camera type eye development GO:0043010 266 0.878
progesterone secretion GO:0042701 1 0.863
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.862
cardiac chamber development GO:0003205 108 0.856
morphogenesis of a polarized epithelium GO:0001738 37 0.847
cardiac chamber morphogenesis GO:0003206 93 0.836
embryonic appendage morphogenesis GO:0035113 126 0.835
syncytiotrophoblast cell differentiation involved in labyrinthine layer development GO:0060715 2 0.835
angiogenesis GO:0001525 201 0.831
embryonic digit morphogenesis GO:0042733 56 0.820
negative regulation of hepatocyte differentiation GO:0070367 1 0.804
establishment of planar polarity involved in neural tube closure GO:0090177 15 0.800
chondrocyte differentiation GO:0002062 72 0.797
regulation of mapk cascade GO:0043408 248 0.795
regulation of catenin import into nucleus GO:0035412 5 0.793
ossification GO:0001503 216 0.777
gland development GO:0048732 330 0.771
positive regulation of protein phosphorylation GO:0001934 242 0.770
organ growth GO:0035265 117 0.758
Fly
placenta development GO:0001890 140 0.755
skeletal system development GO:0001501 356 0.746
cell adhesion GO:0007155 329 0.742
axis elongation involved in somitogenesis GO:0090245 4 0.742
mesenchymal cell development GO:0014031 93 0.728
negative regulation of bmp signaling pathway GO:0030514 35 0.719
embryonic epithelial tube formation GO:0001838 130 0.711
cellular response to growth factor stimulus GO:0071363 197 0.707
Mouse
morphogenesis of a branching structure GO:0001763 203 0.702
appendage development GO:0048736 166 0.695
wnt signaling pathway involved in somitogenesis GO:0090244 4 0.694
embryonic placenta development GO:0001892 98 0.688
cerebellum vasculature morphogenesis GO:0061301 1 0.687
trachea cartilage morphogenesis GO:0060535 4 0.676
mesenchyme development GO:0060485 152 0.664
muscular septum morphogenesis GO:0003150 4 0.660
cell proliferation in midbrain GO:0033278 2 0.657
neural tube formation GO:0001841 108 0.650
regulation of osteoblast differentiation GO:0045667 67 0.648
cerebellum development GO:0021549 77 0.648
neural tube development GO:0021915 160 0.646
blood vessel morphogenesis GO:0048514 285 0.639
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.637
regulation of kinase activity GO:0043549 249 0.627
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration GO:0014834 3 0.624
regulation of establishment of planar polarity involved in neural tube closure GO:0090178 15 0.624
regulation of establishment of planar polarity GO:0090175 28 0.620
establishment of planar polarity of embryonic epithelium GO:0042249 16 0.617
tube formation GO:0035148 140 0.614
embryonic organ morphogenesis GO:0048562 276 0.608
negative regulation of execution phase of apoptosis GO:1900118 4 0.597
sensory organ morphogenesis GO:0090596 242 0.596
stem cell development GO:0048864 219 0.591
Fly
cerebellum vasculature development GO:0061300 1 0.588
primary neural tube formation GO:0014020 95 0.588
cell differentiation involved in embryonic placenta development GO:0060706 26 0.582
regulation of fat cell differentiation GO:0045598 81 0.582
hormone secretion GO:0046879 128 0.576
striated muscle tissue development GO:0014706 293 0.575
Mouse
cardiac ventricle development GO:0003231 83 0.569
epithelial tube formation GO:0072175 130 0.567
embryonic skeletal system development GO:0048706 120 0.566
epithelial cell proliferation GO:0050673 174 0.565
limb development GO:0060173 166 0.564
wnt signaling pathway planar cell polarity pathway GO:0060071 27 0.557
embryonic skeletal system morphogenesis GO:0048704 91 0.555
extracellular matrix organization GO:0030198 147 0.554
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.553
regulation of cellular amine metabolic process GO:0033238 20 0.553
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.552
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.543
heart morphogenesis GO:0003007 178 0.537
embryonic nail plate morphogenesis GO:0035880 3 0.531
bone mineralization GO:0030282 54 0.524
regulation of chorionic trophoblast cell proliferation GO:1901382 1 0.521
ventricular septum development GO:0003281 42 0.520
lung morphogenesis GO:0060425 50 0.519
bone development GO:0060348 120 0.519
skeletal system morphogenesis GO:0048705 203 0.516
positive regulation of osteoblast differentiation GO:0045669 34 0.516
regulation of protein kinase activity GO:0045859 232 0.511
artery development GO:0060840 53 0.504
negative regulation of neuron projection development GO:0010977 50 0.501
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.500
regulation of non canonical wnt signaling pathway GO:2000050 12 0.498
cell type specific apoptotic process GO:0097285 268 0.494
peptidyl tyrosine phosphorylation GO:0018108 143 0.492
mapk cascade GO:0000165 281 0.491
neural tube closure GO:0001843 90 0.490
myeloid cell differentiation GO:0030099 233 0.488
stem cell differentiation GO:0048863 268 0.486
Fly
positive regulation of ossification GO:0045778 47 0.484
positive regulation of mapk cascade GO:0043410 170 0.483
negative regulation of cell proliferation GO:0008285 296 0.483
nephron morphogenesis GO:0072028 69 0.481
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.480
regulation of hormone levels GO:0010817 211 0.474
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.470
planar cell polarity pathway involved in neural tube closure GO:0090179 14 0.465
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.464
morphogenesis of a branching epithelium GO:0061138 193 0.464
regulation of stem cell proliferation GO:0072091 78 0.464
limb morphogenesis GO:0035108 149 0.459
positive regulation of protein modification process GO:0031401 299 0.455
axial mesoderm formation GO:0048320 3 0.455
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.454
extracellular matrix cell signaling GO:0035426 5 0.452
heart trabecula formation GO:0060347 14 0.451
ventricular septum morphogenesis GO:0060412 27 0.446
kidney morphogenesis GO:0060993 83 0.445
trunk neural crest cell migration GO:0036484 4 0.441
tissue remodeling GO:0048771 102 0.441
regulation of binding GO:0051098 111 0.438
embryonic heart tube development GO:0035050 65 0.438
stem cell proliferation GO:0072089 117 0.435
cardiac septum development GO:0003279 59 0.434
ameboidal type cell migration GO:0001667 128 0.432
regulation of cellular amino acid metabolic process GO:0006521 5 0.431
embryonic heart tube morphogenesis GO:0003143 51 0.429
leukocyte differentiation GO:0002521 342 0.428
inner ear morphogenesis GO:0042472 101 0.423
establishment of planar polarity GO:0001736 28 0.423
epidermis development GO:0008544 187 0.421
cardiac septum morphogenesis GO:0060411 46 0.419
regulation of angiogenesis GO:0045765 81 0.419
regulation of cellular ketone metabolic process GO:0010565 66 0.417
somitogenesis GO:0001756 69 0.416
negative regulation of fat cell differentiation GO:0045599 36 0.411
germ line stem cell division GO:0042078 2 0.410
Fly
ear morphogenesis GO:0042471 118 0.405
morphogenesis of embryonic epithelium GO:0016331 159 0.404
negative regulation of prostatic bud formation GO:0060686 4 0.404
ureteric bud development GO:0001657 94 0.404
mesenchyme morphogenesis GO:0072132 32 0.400
regulation of intracellular transport GO:0032386 159 0.387
response to transforming growth factor beta GO:0071559 88 0.386
regulation of cellular response to growth factor stimulus GO:0090287 82 0.384
Mouse
regulation of dermatome development GO:0061183 1 0.383
embryonic camera type eye development GO:0031076 36 0.383
regulation of ossification GO:0030278 112 0.374
response to growth factor GO:0070848 198 0.374
Mouse
cellular amino acid metabolic process GO:0006520 103 0.372
regulation of cell activation GO:0050865 289 0.372
negative regulation of nervous system development GO:0051961 156 0.369
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.366
palate development GO:0060021 76 0.366
regulation of anatomical structure size GO:0090066 178 0.365
mesonephric tubule development GO:0072164 94 0.364
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 10 0.361
mesendoderm development GO:0048382 3 0.360
regulation of epithelial to mesenchymal transition GO:0010717 22 0.359
cellular amine metabolic process GO:0044106 44 0.355
lung development GO:0030324 164 0.353
cardiac muscle tissue development GO:0048738 130 0.352
maintenance of cell number GO:0098727 3 0.352
fat cell differentiation GO:0045444 160 0.352
prostate gland morphogenesis GO:0060512 32 0.351
regeneration GO:0031099 38 0.349
retina vasculature development in camera type eye GO:0061298 17 0.344
regulation of transferase activity GO:0051338 263 0.344
wnt signaling pathway GO:0016055 188 0.342
regulation of cell migration GO:0030334 219 0.342
response to organic cyclic compound GO:0014070 198 0.340
response to extracellular stimulus GO:0009991 127 0.340
metanephric mesenchyme morphogenesis GO:0072133 4 0.339
central nervous system neuron differentiation GO:0021953 162 0.339
neural precursor cell proliferation GO:0061351 121 0.338
glial cell differentiation GO:0010001 131 0.337
hindbrain development GO:0030902 128 0.337
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.337
determination of heart left right asymmetry GO:0061371 48 0.334
regulation of vasculature development GO:1901342 88 0.333
negative regulation of epithelial cell proliferation GO:0050680 64 0.333
epithelial to mesenchymal transition GO:0001837 47 0.331
muscle tissue development GO:0060537 308 0.330
Mouse
hindlimb morphogenesis GO:0035137 42 0.329
positive regulation of programmed cell death GO:0043068 218 0.324
retina vasculature morphogenesis in camera type eye GO:0061299 10 0.322
organelle fission GO:0048285 170 0.321
Fly
response to steroid hormone GO:0048545 56 0.320
polarity specification of proximal distal axis GO:0010085 2 0.315
mesonephric tubule morphogenesis GO:0072171 63 0.315
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.314
branching morphogenesis of an epithelial tube GO:0048754 159 0.312
regulation of map kinase activity GO:0043405 120 0.311
autonomic nervous system development GO:0048483 43 0.309
male sex differentiation GO:0046661 109 0.309
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.308
digestive system development GO:0055123 200 0.301
ear development GO:0043583 200 0.298
regulation of cell adhesion GO:0030155 154 0.297
regulation of neuron differentiation GO:0045664 281 0.295
establishment or maintenance of cell polarity GO:0007163 86 0.292
regulation of receptor activity GO:0010469 41 0.292
nephron tubule morphogenesis GO:0072078 68 0.288
amine metabolic process GO:0009308 45 0.288
regulation of cartilage development GO:0061035 44 0.287
somite development GO:0061053 81 0.286
endochondral bone morphogenesis GO:0060350 50 0.285
bone morphogenesis GO:0060349 78 0.283
odontogenesis GO:0042476 78 0.282
kidney epithelium development GO:0072073 121 0.281
rhythmic process GO:0048511 174 0.280
regulation of planar cell polarity pathway involved in axis elongation GO:2000040 3 0.280
negative regulation of molecular function GO:0044092 258 0.280
mesonephric epithelium development GO:0072163 94 0.280
regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000079 1 0.278
neural crest cell differentiation GO:0014033 54 0.277
regulation of actin cytoskeleton organization GO:0032956 84 0.277
establishment of tissue polarity GO:0007164 28 0.276
cell division GO:0051301 120 0.275
Fly
response to organonitrogen compound GO:0010243 246 0.274
telencephalon development GO:0021537 186 0.273
regulation of homeostatic process GO:0032844 182 0.271
synapse organization GO:0050808 125 0.270
cellular ketone metabolic process GO:0042180 84 0.270
odontogenesis of dentin containing tooth GO:0042475 66 0.269
epithelium migration GO:0090132 63 0.267
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.265
positive regulation of transferase activity GO:0051347 167 0.263
chemotaxis GO:0006935 247 0.262
Fly
type b pancreatic cell proliferation GO:0044342 10 0.260
cardiac muscle tissue morphogenesis GO:0055008 44 0.259
mammary gland morphogenesis GO:0060443 54 0.256
cellular response to hormone stimulus GO:0032870 150 0.256
pallium development GO:0021543 120 0.256
epithelial cell differentiation involved in mammary gland alveolus development GO:0061030 4 0.255
regulation of protein transport GO:0051223 163 0.255
positive regulation of nervous system development GO:0051962 221 0.254
protein localization to nucleus GO:0034504 121 0.252
digestive tract morphogenesis GO:0048546 147 0.251
single organism cell adhesion GO:0098602 156 0.250
tube closure GO:0060606 91 0.250
positive regulation of cellular amine metabolic process GO:0033240 5 0.249
synaptic transmission GO:0007268 329 0.248
cardiac ventricle morphogenesis GO:0003208 50 0.247
positive regulation of homeostatic process GO:0032846 64 0.247
peptidyl amino acid modification GO:0018193 336 0.246
regulation of tight junction assembly GO:2000810 2 0.242
connective tissue development GO:0061448 179 0.242
labyrinthine layer development GO:0060711 49 0.242
carbohydrate homeostasis GO:0033500 128 0.241
forebrain development GO:0030900 302 0.236
apoptotic signaling pathway GO:0097190 306 0.234
embryonic placenta morphogenesis GO:0060669 25 0.234
spinal cord development GO:0021510 81 0.234
wound healing GO:0042060 157 0.233
midbrain hindbrain boundary maturation GO:0021732 1 0.233
stem cell maintenance GO:0019827 130 0.232
Fly
negative regulation of neuron differentiation GO:0045665 101 0.232
respiratory tube development GO:0030323 167 0.231
neuron migration GO:0001764 122 0.230
regulation of neuron projection development GO:0010975 169 0.229
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.229
negative regulation of catenin import into nucleus GO:0035414 2 0.228
positive regulation of muscle tissue development GO:1901863 32 0.227
Mouse
innate immune response GO:0045087 157 0.227
septum primum development GO:0003284 4 0.227
regulation of cell substrate adhesion GO:0010810 73 0.226
cell cell junction organization GO:0045216 72 0.226
retina development in camera type eye GO:0060041 119 0.225
regulation of muscle tissue development GO:1901861 97 0.224
Mouse
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.224
mesoderm formation GO:0001707 62 0.222
chorionic trophoblast cell proliferation GO:0097360 1 0.222
cerebral cortex development GO:0021987 86 0.218
regulation of cell cycle GO:0051726 281 0.218
Fly
regulation of hepatocyte differentiation GO:0070366 2 0.217
regulation of stem cell differentiation GO:2000736 50 0.217
trabecula formation GO:0060343 24 0.215
regulation of protein serine threonine kinase activity GO:0071900 157 0.214
cell junction organization GO:0034330 77 0.214
positive regulation of cell adhesion GO:0045785 80 0.213
regulation of system process GO:0044057 200 0.213
nephron tubule development GO:0072080 84 0.212
hair follicle development GO:0001942 85 0.212
prostate gland development GO:0030850 48 0.212
forelimb morphogenesis GO:0035136 40 0.210
digestive tract development GO:0048565 190 0.209
positive regulation of map kinase activity GO:0043406 84 0.207
locomotory behavior GO:0007626 195 0.204
response to radiation GO:0009314 165 0.204
biomineral tissue development GO:0031214 64 0.201
non canonical wnt signaling pathway involved in heart development GO:0061341 3 0.200
determination of left right symmetry GO:0007368 80 0.200
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 0.199
positive regulation of kinase activity GO:0033674 155 0.199
negative regulation of ossification GO:0030279 49 0.197
positive regulation of apoptotic process GO:0043065 217 0.197
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.197
labyrinthine layer morphogenesis GO:0060713 21 0.196
cardiac atrium development GO:0003230 24 0.196
vascular endothelial growth factor receptor signaling pathway GO:0048010 24 0.194
canonical wnt signaling pathway GO:0060070 130 0.194
nuclear transport GO:0051169 139 0.192
single organism nuclear import GO:1902593 95 0.192
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.192
regulation of actin filament based process GO:0032970 99 0.191
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.190
t cell activation GO:0042110 289 0.189
positive regulation of protein kinase activity GO:0045860 144 0.189
gastrulation GO:0007369 116 0.189
development of primary female sexual characteristics GO:0046545 73 0.187
nephron epithelium morphogenesis GO:0072088 68 0.186
metencephalon development GO:0022037 89 0.183
paraxial mesoderm development GO:0048339 18 0.182
kidney mesenchyme morphogenesis GO:0072131 4 0.182
peptidyl tyrosine modification GO:0018212 145 0.182
synapse assembly GO:0007416 56 0.182
regulation of cell motility GO:2000145 236 0.180
outflow tract morphogenesis GO:0003151 53 0.179
cellular metal ion homeostasis GO:0006875 151 0.177
negative regulation of cell development GO:0010721 169 0.176
tissue regeneration GO:0042246 22 0.176
peptide secretion GO:0002790 114 0.176
planar cell polarity pathway involved in heart morphogenesis GO:0061346 3 0.176
cerebral cortex cell migration GO:0021795 44 0.175
central nervous system vasculogenesis GO:0022009 3 0.175
oviduct development GO:0060066 3 0.173
molting cycle GO:0042303 90 0.173
regulation of protein localization GO:0032880 231 0.172
cellular response to lipid GO:0071396 145 0.170
regulation of leukocyte differentiation GO:1902105 159 0.170
hypophysis morphogenesis GO:0048850 3 0.169
neural crest cell migration involved in autonomic nervous system development GO:1901166 5 0.168
catenin import into nucleus GO:0035411 6 0.167
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.166
peptide metabolic process GO:0006518 46 0.166
appendage morphogenesis GO:0035107 149 0.164
regulation of organelle organization GO:0033043 289 0.162
hair cycle GO:0042633 90 0.161
multicellular organism growth GO:0035264 161 0.160
Fly
paraxial mesodermal cell differentiation GO:0048342 2 0.160
developmental maturation GO:0021700 193 0.159
regulation of secretion by cell GO:1903530 249 0.159
positive regulation of ureteric bud formation GO:0072107 3 0.158
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.158
glucose homeostasis GO:0042593 128 0.158
cell proliferation in hindbrain GO:0021534 10 0.158
protein import GO:0017038 101 0.156
lung induction GO:0060492 3 0.156
cardiocyte differentiation GO:0035051 87 0.155
cytoplasmic transport GO:0016482 234 0.154
mesonephros development GO:0001823 97 0.153
peptide hormone secretion GO:0030072 109 0.153
negative regulation of cellular component organization GO:0051129 194 0.153
hippocampus development GO:0021766 52 0.150
positive regulation of cell development GO:0010720 237 0.150
regulation of ion homeostasis GO:2000021 64 0.150
negative regulation of cardiac chamber morphogenesis GO:1901220 2 0.149
skin development GO:0043588 220 0.148
positive regulation of cardiac muscle cell proliferation GO:0060045 15 0.148
positive regulation of epithelial cell proliferation GO:0050679 68 0.147
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.147
regulation of epithelial cell migration GO:0010632 35 0.146
nuclear import GO:0051170 95 0.146
establishment of planar polarity involved in nephron morphogenesis GO:0072046 1 0.145
canonical wnt signaling pathway involved in regulation of type b pancreatic cell proliferation GO:0044343 1 0.145
regulation of biomineral tissue development GO:0070167 33 0.144
regulation of myeloid cell differentiation GO:0045637 96 0.142
insulin secretion GO:0030073 89 0.142
circulatory system process GO:0003013 197 0.141
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.141
Mouse
segmentation GO:0035282 93 0.141
metanephros development GO:0001656 79 0.141
ensheathment of neurons GO:0007272 76 0.140
endocrine system development GO:0035270 98 0.140
t cell differentiation in thymus GO:0033077 77 0.140
muscle system process GO:0003012 141 0.140
peptide transport GO:0015833 133 0.140
forebrain morphogenesis GO:0048853 17 0.139
regulation of wnt signaling pathway GO:0030111 123 0.139
regulation of response to wounding GO:1903034 189 0.139
negative regulation of smooth muscle cell migration GO:0014912 2 0.139
neural crest cell migration GO:0001755 32 0.139
negative regulation of cell projection organization GO:0031345 56 0.138
brown fat cell differentiation GO:0050873 36 0.138
negative regulation of mitotic cell cycle embryonic GO:0045976 2 0.136
regulation of secretion GO:0051046 274 0.136
negative regulation of kinase activity GO:0033673 81 0.136
cardiac right atrium morphogenesis GO:0003213 3 0.136
muscle cell differentiation GO:0042692 261 0.136
mesenchymal cell proliferation GO:0010463 44 0.135
negative regulation of stem cell differentiation GO:2000737 14 0.135
cardiac epithelial to mesenchymal transition GO:0060317 18 0.135
blood circulation GO:0008015 195 0.133
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.133
renal tubule development GO:0061326 87 0.133
cerebellum formation GO:0021588 1 0.133
establishment of protein localization to organelle GO:0072594 118 0.133
skeletal muscle tissue regeneration GO:0043403 20 0.132
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.132
regulation of protein import into nucleus GO:0042306 52 0.132
transforming growth factor beta2 production GO:0032906 2 0.131
trabecula morphogenesis GO:0061383 40 0.131
regulation of peptide transport GO:0090087 91 0.130
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis GO:2000166 1 0.128
endothelial cell migration GO:0043542 44 0.128
apoptotic process involved in morphogenesis GO:0060561 25 0.127
t cell differentiation GO:0030217 174 0.127
substrate adhesion dependent cell spreading GO:0034446 30 0.127
regulation of smad protein import into nucleus GO:0060390 3 0.127
metanephric nephron epithelium development GO:0072243 19 0.126
positive regulation of apoptotic signaling pathway GO:2001235 95 0.126
positive regulation of branching involved in lung morphogenesis GO:0061047 4 0.126
muscle tissue morphogenesis GO:0060415 53 0.125
amide transport GO:0042886 138 0.125
regulation of ureteric bud formation GO:0072106 3 0.125
negative regulation of phosphorus metabolic process GO:0010563 184 0.125
ureteric bud morphogenesis GO:0060675 62 0.124
regulation of action potential GO:0098900 4 0.123
platelet activation GO:0030168 40 0.123
positive regulation of angiogenesis GO:0045766 46 0.123
cell maturation GO:0048469 127 0.123
cognition GO:0050890 149 0.123
protein localization to organelle GO:0033365 185 0.123
female sex differentiation GO:0046660 84 0.122
dermatome development GO:0061054 1 0.122
somatic stem cell maintenance GO:0035019 47 0.121
cell cell signaling involved in mammary gland development GO:0060764 2 0.121
positive regulation of anagen GO:0051885 1 0.120
nephric duct formation GO:0072179 4 0.120
regulation of peptide secretion GO:0002791 77 0.120
branching involved in ureteric bud morphogenesis GO:0001658 56 0.119
neural crest cell development GO:0014032 48 0.119
regulation of chemotaxis GO:0050920 53 0.119
lateral mesoderm morphogenesis GO:0048369 3 0.118
positive regulation of peptidyl serine phosphorylation GO:0033138 25 0.118
regulation of establishment of protein localization GO:0070201 181 0.118
regulation of cellular response to stress GO:0080135 159 0.117
forebrain neuron differentiation GO:0021879 52 0.117
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.116
midbrain hindbrain boundary development GO:0030917 9 0.116
regulation of transmembrane transport GO:0034762 128 0.116
positive regulation of cardioblast differentiation GO:0051891 3 0.115
wnt signaling pathway calcium modulating pathway GO:0007223 2 0.114
regulation of cell projection organization GO:0031344 206 0.113
lateral sprouting involved in mammary gland duct morphogenesis GO:0060599 2 0.112
negative regulation of alcohol biosynthetic process GO:1902931 4 0.112
response to acid chemical GO:0001101 111 0.112
vascular process in circulatory system GO:0003018 62 0.111
lung vasculature development GO:0060426 7 0.111
post anal tail morphogenesis GO:0036342 23 0.111
renal vesicle induction GO:0072034 3 0.111
oxidation reduction process GO:0055114 342 0.110
regulation of hormone secretion GO:0046883 88 0.109
epithelial cell migration GO:0010631 63 0.109
positive regulation of cell substrate adhesion GO:0010811 47 0.109
tendon cell differentiation GO:0035990 4 0.109
extracellular structure organization GO:0043062 148 0.108
cell substrate adhesion GO:0031589 130 0.107
positive regulation of neural precursor cell proliferation GO:2000179 42 0.107
response to estrogen GO:0043627 24 0.107
axonogenesis GO:0007409 274 0.106
Fly
genetic imprinting GO:0071514 27 0.105
regulation of ion transport GO:0043269 215 0.105
nephron tubule formation GO:0072079 20 0.105
renal outer medulla development GO:0072054 2 0.105
nephrogenic mesenchyme morphogenesis GO:0072134 2 0.104
axon guidance GO:0007411 141 0.104
Fly
organic hydroxy compound metabolic process GO:1901615 203 0.103
negative regulation of embryonic development GO:0045992 22 0.103
hemostasis GO:0007599 78 0.103
embryonic eye morphogenesis GO:0048048 29 0.102
sympathetic nervous system development GO:0048485 22 0.102
sympathetic neuron projection extension GO:0097490 4 0.102
establishment of epithelial cell apical basal polarity GO:0045198 5 0.102
regulation of tissue remodeling GO:0034103 38 0.102
regulation of bone mineralization GO:0030500 31 0.100
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.100
Mouse
positive regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000081 1 0.099
b cell activation GO:0042113 161 0.099
sprouting angiogenesis GO:0002040 26 0.099
brain morphogenesis GO:0048854 32 0.099
regulation of intracellular protein transport GO:0033157 82 0.099
negative regulation of phosphate metabolic process GO:0045936 184 0.098
negative regulation of synapse assembly GO:0051964 3 0.098
skeletal muscle organ development GO:0060538 163 0.098
Mouse
positive regulation of catenin import into nucleus GO:0035413 2 0.098
cardiac atrium morphogenesis GO:0003209 23 0.097
renal tubule morphogenesis GO:0061333 72 0.097
forebrain cell migration GO:0021885 58 0.097
heart trabecula morphogenesis GO:0061384 26 0.097
hepaticobiliary system development GO:0061008 67 0.096
aortic valve morphogenesis GO:0003180 4 0.096
regulation of ketone biosynthetic process GO:0010566 2 0.096
positive regulation of heart growth GO:0060421 18 0.096

Gpc3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org