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Mus musculus

2 genes annotated in mouse

Multi-species View

cell proliferation in midbrain

GO:0033278

The multiplication or reproduction of cells, resulting in the expansion of a cell population in the midbrain.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cell proliferation in midbrain"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cell proliferation in midbrain" (in gray)

Name	Description	Probability	Func Analog Organism
Gli3	GLI-Kruppel family member GLI3	1.000
Shh	sonic hedgehog	1.000
Bmp4	bone morphogenetic protein 4	1.000
Sox9	SRY-box containing gene 9	0.999
Foxc1	forkhead box C1	0.996
Prrx1	paired related homeobox 1	0.990
Vangl2	vang-like 2 (van gogh, Drosophila)	0.988
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.977
Gli2	GLI-Kruppel family member GLI2	0.977
Smo	smoothened homolog (Drosophila)	0.954
Ctnnb1	catenin (cadherin associated protein), beta 1	0.940
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.937
Eya1	eyes absent 1 homolog (Drosophila)	0.922
Tgfb2	transforming growth factor, beta 2	0.917
Wnt5a	wingless-related MMTV integration site 5A	0.897
Fgfr1	fibroblast growth factor receptor 1	0.879
Bmp7	bone morphogenetic protein 7	0.867
Foxc2	forkhead box C2	0.853
Tcfap2a	transcription factor AP-2, alpha	0.834
Otx2	orthodenticle homolog 2 (Drosophila)	0.827
Msx1	homeobox, msh-like 1	0.814
Dlx5	distal-less homeobox 5	0.788
Pax3	paired box gene 3	0.780
Gopc	golgi associated PDZ and coiled-coil motif containing	0.745
Pbx1	pre B-cell leukemia transcription factor 1	0.683
Fgfr3	fibroblast growth factor receptor 3	0.675
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.671
Gpc3	glypican 3	0.657
Sox2	SRY-box containing gene 2	0.611
Vegfa	vascular endothelial growth factor A	0.575
Fzd1	frizzled homolog 1 (Drosophila)	0.497	Mouse
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.475
Pitx2	paired-like homeodomain transcription factor 2	0.443
Acvr1	activin A receptor, type 1	0.429
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.423
Fgfr2	fibroblast growth factor receptor 2	0.404	Zebrafish
Fgf10	fibroblast growth factor 10	0.365
Tbx1	T-box 1	0.361
Prrx2	paired related homeobox 2	0.356
Hoxa2	homeobox A2	0.348
Pax6	paired box gene 6	0.336
Rarb	retinoic acid receptor, beta	0.306
Tbx3	T-box 3	0.294
Sox11	SRY-box containing gene 11	0.285
Foxg1	forkhead box G1	0.273
Fzd8	frizzled homolog 8 (Drosophila)	0.255	Mouse
Msx2	homeobox, msh-like 2	0.251
Dlg4	discs, large homolog 4 (Drosophila)	0.249
Ptch1	patched homolog 1	0.247
Jag1	jagged 1	0.234
Fzd2	frizzled homolog 2 (Drosophila)	0.234	Mouse
Hes1	hairy and enhancer of split 1 (Drosophila)	0.211
Smad6	MAD homolog 6 (Drosophila)	0.176
Chrd	chordin	0.172
Fbln1	fibulin 1	0.166
Grb10	growth factor receptor bound protein 10	0.158
Gas1	growth arrest specific 1	0.155
Sox4	SRY-box containing gene 4	0.141
Runx2	runt related transcription factor 2	0.140
Twist2	twist homolog 2 (Drosophila)	0.132
Bmp2	bone morphogenetic protein 2	0.131
Dlg2	discs, large homolog 2 (Drosophila)	0.131
Nog	noggin	0.127
Bmp5	bone morphogenetic protein 5	0.126
Isl1	ISL1 transcription factor, LIM/homeodomain	0.124
Hoxa1	homeobox A1	0.110
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.103
Cachd1	cache domain containing 1	0.099
Zic3	zinc finger protein of the cerebellum 3	0.098
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.092
Zeb1	zinc finger E-box binding homeobox 1	0.092
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.092
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.092
Fzd7	frizzled homolog 7 (Drosophila)	0.090	Mouse
Meox2	mesenchyme homeobox 2	0.087
Smad3	MAD homolog 3 (Drosophila)	0.084
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.084
Ednra	endothelin receptor type A	0.081
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.080
Fjx1	four jointed box 1 (Drosophila)	0.080
Zic1	zinc finger protein of the cerebellum 1	0.080
Efnb2	ephrin B2	0.078
Alx1	ALX homeobox 1	0.076
Dlg1	discs, large homolog 1 (Drosophila)	0.072
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.069
Gbx2	gastrulation brain homeobox 2	0.067
Zfhx4	zinc finger homeodomain 4	0.064
Fzd4	frizzled homolog 4 (Drosophila)	0.063	Mouse
Hoxa5	homeobox A5	0.063
Ntf3	neurotrophin 3	0.060
Foxd1	forkhead box D1	0.060
Sfrp1	secreted frizzled-related protein 1	0.060
Lrp6	low density lipoprotein receptor-related protein 6	0.059
Npr3	natriuretic peptide receptor 3	0.059
Sfrp2	secreted frizzled-related protein 2	0.058
Sall1	sal-like 1 (Drosophila)	0.058
Ebf3	early B-cell factor 3	0.054
Tcf21	transcription factor 21	0.053
Trp63	transformation related protein 63	0.053
Hand2	heart and neural crest derivatives expressed transcript 2	0.052
Nrcam	neuron-glia-CAM-related cell adhesion molecule	0.051
Emp2	epithelial membrane protein 2	0.051
Rarg	retinoic acid receptor, gamma	0.049
Efnb1	ephrin B1	0.049
Sema5a	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	0.048
Fgf8	fibroblast growth factor 8	0.047
Tspan12	tetraspanin 12	0.046
Zfp185	zinc finger protein 185	0.046
Tbx15	T-box 15	0.046
Col2a1	collagen, type II, alpha 1	0.045
Tgfbr3	transforming growth factor, beta receptor III	0.045
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.045
Ndp	Norrie disease (pseudoglioma) (human)	0.044
Egfr	epidermal growth factor receptor	0.043
Hoxa10	homeobox A10	0.043
Ctf1	cardiotrophin 1	0.042
Tbx2	T-box 2	0.041
Hoxb6	homeobox B6	0.041
Sema3a	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	0.039
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.038
Ephb3	Eph receptor B3	0.038
Ncam1	neural cell adhesion molecule 1	0.038
En2	engrailed 2	0.037
Col4a5	collagen, type IV, alpha 5	0.036
Itga8	integrin alpha 8	0.036
Pax2	paired box gene 2	0.036
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.035
Ephb2	Eph receptor B2	0.035
Hoxa3	homeobox A3	0.035
Col11a1	collagen, type XI, alpha 1	0.034
Tpbg	trophoblast glycoprotein	0.034
Tead2	TEA domain family member 2	0.034
Nf1	neurofibromatosis 1	0.034
Epha4	Eph receptor A4	0.034
Hoxd9	homeobox D9	0.034
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.033
Lama5	laminin, alpha 5	0.032
Efna2	ephrin A2	0.032
Irs1	insulin receptor substrate 1	0.031
Rara	retinoic acid receptor, alpha	0.031
Apc	adenomatosis polyposis coli	0.030
Tnfrsf19	tumor necrosis factor receptor superfamily, member 19	0.030
Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.030
Zfp503	zinc finger protein 503	0.029
Tgfbr2	transforming growth factor, beta receptor II	0.029
En1	engrailed 1	0.029
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.028
Id4	inhibitor of DNA binding 4	0.028
Gja1	gap junction protein, alpha 1	0.028
Foxa2	forkhead box A2	0.028
Ednrb	endothelin receptor type B	0.028
Pcdh18	protocadherin 18	0.028
Igfbp2	insulin-like growth factor binding protein 2	0.027
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.027
Twist1	twist homolog 1 (Drosophila)	0.027
Npas3	neuronal PAS domain protein 3	0.027
Chrna7	cholinergic receptor, nicotinic, alpha polypeptide 7	0.027
Hoxb5	homeobox B5	0.026
Capn6	calpain 6	0.026
Gjc1	gap junction protein, gamma 1	0.025
Nudt11	nudix (nucleoside diphosphate linked moiety X)-type motif 11	0.025
Dab1	disabled homolog 1 (Drosophila)	0.025
Gdf10	growth differentiation factor 10	0.024
Lef1	lymphoid enhancer binding factor 1	0.024
Rxra	retinoid X receptor alpha	0.024
Ptk7	PTK7 protein tyrosine kinase 7	0.024
Hoxd8	homeobox D8	0.024
Pcdh10	protocadherin 10	0.023
Irx5	Iroquois related homeobox 5 (Drosophila)	0.023
Kif3a	kinesin family member 3A	0.023
Sh3rf1	SH3 domain containing ring finger 1	0.023
Zfhx3	zinc finger homeobox 3	0.023
Meis2	Meis homeobox 2	0.023
Efna1	ephrin A1	0.023
Hoxb3	homeobox B3	0.023
Apcdd1	adenomatosis polyposis coli down-regulated 1	0.022
Satb2	special AT-rich sequence binding protein 2	0.022
Arhgap29	Rho GTPase activating protein 29	0.021
Dlx2	distal-less homeobox 2	0.021
Kcnk2	potassium channel, subfamily K, member 2	0.021
Hoxa9	homeobox A9	0.021
Fzd6	frizzled homolog 6 (Drosophila)	0.021
Maf	avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog	0.021
Mn1	meningioma 1	0.021
Fign	fidgetin	0.021
Syt9	synaptotagmin IX	0.021
Mrc2	mannose receptor, C type 2	0.020
Tll1	tolloid-like	0.020
Smoc2	SPARC related modular calcium binding 2	0.020
Sardh	sarcosine dehydrogenase	0.020
Pax9	paired box gene 9	0.020
Ddr2	discoidin domain receptor family, member 2	0.019
Ptprz1	protein tyrosine phosphatase, receptor type Z, polypeptide 1	0.019
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.019
Ptprk	protein tyrosine phosphatase, receptor type, K	0.019
Tcfap2c	transcription factor AP-2, gamma	0.019
AI464131	expressed sequence AI464131	0.018
Nkain1	Na+/K+ transporting ATPase interacting 1	0.018
Ebf2	early B-cell factor 2	0.018
Ctnnal1	catenin (cadherin associated protein), alpha-like 1	0.018
Ret	ret proto-oncogene	0.018
Neo1	neogenin	0.018
Arhgef25	Rho guanine nucleotide exchange factor (GEF) 25	0.018
Efna5	ephrin A5	0.018
Sh3d19	SH3 domain protein D19	0.017
Ptgfr	prostaglandin F receptor	0.017
Sema3c	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	0.017
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.017
Gm4788	predicted gene 4788	0.017
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.017
Sall2	sal-like 2 (Drosophila)	0.017
Trp53	transformation related protein 53	0.017
Sh3gl2	SH3-domain GRB2-like 2	0.017
Foxp2	forkhead box P2	0.017
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.017
Ltbp3	latent transforming growth factor beta binding protein 3	0.017
Emx2	empty spiracles homolog 2 (Drosophila)	0.017
Six5	sine oculis-related homeobox 5 homolog (Drosophila)	0.017
Atp1b2	ATPase, Na+/K+ transporting, beta 2 polypeptide	0.017
Col9a1	collagen, type IX, alpha 1	0.017
Arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.017
Notch2	Notch gene homolog 2 (Drosophila)	0.017
Ar	androgen receptor	0.016
Ttl	tubulin tyrosine ligase	0.016
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.016
Insm1	insulinoma-associated 1	0.016
Lhx1	LIM homeobox protein 1	0.016
Etv4	ets variant gene 4 (E1A enhancer binding protein, E1AF)	0.016
Dll1	delta-like 1 (Drosophila)	0.016
Rimklb	ribosomal modification protein rimK-like family member B	0.016
Amotl2	angiomotin-like 2	0.016
Cxadr	coxsackie virus and adenovirus receptor	0.016
Ptpru	protein tyrosine phosphatase, receptor type, U	0.015
Epb4.1l4b	erythrocyte protein band 4.1-like 4b	0.015
Otx1	orthodenticle homolog 1 (Drosophila)	0.015
Sall3	sal-like 3 (Drosophila)	0.015
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.015
Wnt4	wingless-related MMTV integration site 4	0.015
Ocln	occludin	0.015
Btbd3	BTB (POZ) domain containing 3	0.015
Dach1	dachshund 1 (Drosophila)	0.015
Pcsk6	proprotein convertase subtilisin/kexin type 6	0.015
Mecom	MDS1 and EVI1 complex locus	0.015
Pthlh	parathyroid hormone-like peptide	0.015
Slc16a2	solute carrier family 16 (monocarboxylic acid transporters), member 2	0.014
Ntn1	netrin 1	0.014
Mmp16	matrix metallopeptidase 16	0.014
Rbfox2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.014
Bmp1	bone morphogenetic protein 1	0.014
Boc	biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein	0.014
Hoxb2	homeobox B2	0.014
Prox1	prospero-related homeobox 1	0.014
Foxd3	forkhead box D3	0.014
Nkx3-1	NK-3 transcription factor, locus 1 (Drosophila)	0.014
Twsg1	twisted gastrulation homolog 1 (Drosophila)	0.014
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.014
Ghr	growth hormone receptor	0.014
S1pr3	sphingosine-1-phosphate receptor 3	0.014
Npr2	natriuretic peptide receptor 2	0.014
Ptch2	patched homolog 2	0.014
Kcnd3	potassium voltage-gated channel, Shal-related family, member 3	0.014
Met	met proto-oncogene	0.014
Wnt1	wingless-related MMTV integration site 1	0.014
Lpar4	lysophosphatidic acid receptor 4	0.013
Prkci	protein kinase C, iota	0.013
Mark1	MAP/microtubule affinity-regulating kinase 1	0.013
Il17rd	interleukin 17 receptor D	0.013
Axin2	axin2	0.013
Sulf2	sulfatase 2	0.013
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.013
Lrig3	leucine-rich repeats and immunoglobulin-like domains 3	0.013
Dll3	delta-like 3 (Drosophila)	0.013
Mtap1b	microtubule-associated protein 1B	0.013
Dvl2	dishevelled 2, dsh homolog (Drosophila)	0.013
Wt1	Wilms tumor 1 homolog	0.013
Pten	phosphatase and tensin homolog	0.013
St8sia2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.013
Lpar1	lysophosphatidic acid receptor 1	0.013
Angpt1	angiopoietin 1	0.013
Epha3	Eph receptor A3	0.013
Pou3f3	POU domain, class 3, transcription factor 3	0.013
Fgf9	fibroblast growth factor 9	0.012
Cldn1	claudin 1	0.012
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.012
Hoxd10	homeobox D10	0.012
Lmx1a	LIM homeobox transcription factor 1 alpha	0.012
Lrp2	low density lipoprotein receptor-related protein 2	0.012
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.012
Nrk	Nik related kinase	0.012
Neurod1	neurogenic differentiation 1	0.012
Gfpt2	glutamine fructose-6-phosphate transaminase 2	0.012
Wnt7b	wingless-related MMTV integration site 7B	0.012
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.012
Bcl2	B-cell leukemia/lymphoma 2	0.012
Arvcf	armadillo repeat gene deleted in velo-cardio-facial syndrome	0.012
Tcf15	transcription factor 15	0.012
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.012
Dkk2	dickkopf homolog 2 (Xenopus laevis)	0.012
Prkd1	protein kinase D1	0.012
Hhip	Hedgehog-interacting protein	0.012
Fam19a5	family with sequence similarity 19, member A5	0.012
Ptprg	protein tyrosine phosphatase, receptor type, G	0.012
Mafb	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.012
Gli1	GLI-Kruppel family member GLI1	0.012
Aplnr	apelin receptor	0.012
Sox17	SRY-box containing gene 17	0.011
St3gal2	ST3 beta-galactoside alpha-2,3-sialyltransferase 2	0.011
Sema3e	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E	0.011
Gdnf	glial cell line derived neurotrophic factor	0.011
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.011
Epha7	Eph receptor A7	0.011
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.011
Chrna3	cholinergic receptor, nicotinic, alpha polypeptide 3	0.011
Sox21	SRY-box containing gene 21	0.011
Cdh6	cadherin 6	0.011
Dvl3	dishevelled 3, dsh homolog (Drosophila)	0.011
Efs	embryonal Fyn-associated substrate	0.011
Irf6	interferon regulatory factor 6	0.011
Ptprf	protein tyrosine phosphatase, receptor type, F	0.011
Sox18	SRY-box containing gene 18	0.011
Has2	hyaluronan synthase 2	0.011
Nr2f1	nuclear receptor subfamily 2, group F, member 1	0.011
Lrp5	low density lipoprotein receptor-related protein 5	0.011
Fgfrl1	fibroblast growth factor receptor-like 1	0.011
Yap1	yes-associated protein 1	0.011
Aif1l	allograft inflammatory factor 1-like	0.011
Chd7	chromodomain helicase DNA binding protein 7	0.011
Esrp2	epithelial splicing regulatory protein 2	0.011
Slc1a3	solute carrier family 1 (glial high affinity glutamate transporter), member 3	0.011
Gpd1	glycerol-3-phosphate dehydrogenase 1 (soluble)	0.011
Lrig1	leucine-rich repeats and immunoglobulin-like domains 1	0.011
Igfbp5	insulin-like growth factor binding protein 5	0.010
Cldn8	claudin 8	0.010
Epn2	epsin 2	0.010
Kcna1	potassium voltage-gated channel, shaker-related subfamily, member 1	0.010
Wwtr1	WW domain containing transcription regulator 1	0.010
Npnt	nephronectin	0.010
Bmper	BMP-binding endothelial regulator	0.010
Plagl1	pleiomorphic adenoma gene-like 1	0.010
Mia1	melanoma inhibitory activity 1	0.010
Mfap2	microfibrillar-associated protein 2	0.010
Lmo1	LIM domain only 1	0.010
Tmem54	transmembrane protein 54	0.010
Pkdcc	protein kinase domain containing, cytoplasmic	0.010
Cntnap2	contactin associated protein-like 2	0.010
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.010
Zbtb12	zinc finger and BTB domain containing 12	0.010
Ctnnd1	catenin (cadherin associated protein), delta 1	0.010
Fam84a	family with sequence similarity 84, member A	0.010
Ryk	receptor-like tyrosine kinase	0.010