Mus musculus

0 known processes

Gzmk

granzyme K

Gzmk biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.988
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.977
positive regulation of natural killer cell mediated immunity GO:0002717 16 0.955
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.931
response to molecule of fungal origin GO:0002238 4 0.918
regulation of defense response GO:0031347 233 0.912
positive regulation of defense response GO:0031349 124 0.912
cell killing GO:0001906 67 0.858
Mouse
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.854
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.843
regulation of interferon gamma production GO:0032649 57 0.815
regulation of leukocyte mediated immunity GO:0002703 104 0.811
regulation of cytokine production GO:0001817 266 0.799
regulation of natural killer cell mediated immunity GO:0002715 19 0.798
cytokine production GO:0001816 319 0.793
leukocyte mediated immunity GO:0002443 174 0.786
Mouse
positive regulation of lymphocyte proliferation GO:0050671 70 0.703
immune effector process GO:0002252 321 0.667
Mouse
response to molecule of bacterial origin GO:0002237 143 0.638
Mouse
defense response to other organism GO:0098542 197 0.628
Mouse
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.615
positive regulation of leukocyte mediated immunity GO:0002705 70 0.614
natural killer cell mediated cytotoxicity GO:0042267 29 0.606
regulation of cell killing GO:0031341 40 0.593
positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 0.581
leukocyte activation involved in immune response GO:0002366 126 0.576
leukocyte mediated cytotoxicity GO:0001909 62 0.572
Mouse
positive regulation of innate immune response GO:0045089 80 0.564
cell activation involved in immune response GO:0002263 126 0.561
innate immune response GO:0045087 157 0.548
positive regulation of cytokine production GO:0001819 174 0.532
positive regulation of lymphocyte activation GO:0051251 140 0.513
lymphocyte mediated immunity GO:0002449 139 0.508
Mouse
positive regulation of cell killing GO:0031343 33 0.505
regulation of innate immune response GO:0045088 91 0.500
regulation of lymphocyte mediated immunity GO:0002706 84 0.497
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.497
interferon gamma production GO:0032609 67 0.483
t cell differentiation GO:0030217 174 0.470
regulation of monocyte chemotaxis GO:0090025 3 0.463
natural killer cell activation GO:0030101 44 0.462
g protein coupled receptor signaling pathway GO:0007186 243 0.455
natural killer cell mediated immunity GO:0002228 29 0.447
inflammatory response GO:0006954 244 0.445
positive regulation of immune effector process GO:0002699 107 0.444
positive regulation of t cell costimulation GO:2000525 2 0.421
regulation of lymphocyte activation GO:0051249 240 0.413
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.408
interleukin 12 secretion GO:0072610 3 0.398
leukocyte proliferation GO:0070661 172 0.398
positive regulation of inflammatory response GO:0050729 47 0.396
alpha beta t cell activation GO:0046631 91 0.377
reactive oxygen species biosynthetic process GO:1903409 8 0.377
positive regulation of thymocyte migration GO:2000412 2 0.362
regulation of inflammatory response to antigenic stimulus GO:0002861 21 0.362
positive regulation of interferon gamma production GO:0032729 39 0.360
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.360
Mouse
defense response to bacterium GO:0042742 119 0.358
Mouse
positive regulation of t cell proliferation GO:0042102 52 0.344
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.339
reactive oxygen species metabolic process GO:0072593 84 0.324
cell type specific apoptotic process GO:0097285 268 0.320
cellular response to biotic stimulus GO:0071216 92 0.319
immune response regulating signaling pathway GO:0002764 125 0.319
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.312
positive regulation of t cell activation GO:0050870 101 0.311
detection of fungus GO:0016046 2 0.304
leukocyte differentiation GO:0002521 342 0.302
response to lipopolysaccharide GO:0032496 128 0.297
Mouse
regulation of natural killer cell mediated cytotoxicity GO:0042269 19 0.288
immune response activating signal transduction GO:0002757 116 0.288
sequestering of calcium ion GO:0051208 18 0.285
production of molecular mediator of immune response GO:0002440 103 0.279
cell chemotaxis GO:0060326 81 0.272
single organismal cell cell adhesion GO:0016337 131 0.272
cellular response to lipopolysaccharide GO:0071222 77 0.271
positive regulation of monocyte chemotaxis GO:0090026 2 0.264
regulation of reactive oxygen species metabolic process GO:2000377 40 0.263
reactive nitrogen species metabolic process GO:2001057 0 0.261
cellular response to lipid GO:0071396 145 0.259
helper t cell chemotaxis GO:0035704 1 0.258
regulation of cell activation GO:0050865 289 0.256
regulation of alpha beta t cell proliferation GO:0046640 18 0.254
regulation of t cell activation GO:0050863 170 0.254
mature dendritic cell differentiation GO:0097029 3 0.252
positive regulation of leukocyte proliferation GO:0070665 73 0.249
regulation of tumor necrosis factor production GO:0032680 49 0.249
cytokine mediated signaling pathway GO:0019221 115 0.249
cellular response to molecule of bacterial origin GO:0071219 83 0.247
detection of yeast GO:0001879 2 0.247
regulation of epithelial cell proliferation GO:0050678 141 0.245
negative regulation of macrophage apoptotic process GO:2000110 3 0.245
inflammatory cell apoptotic process GO:0006925 11 0.239
positive regulation of cell activation GO:0050867 158 0.237
eosinophil degranulation GO:0043308 1 0.236
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.236
eosinophil activation GO:0043307 1 0.227
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.225
regulation of secretion by cell GO:1903530 249 0.223
negative regulation of eosinophil degranulation GO:0043310 1 0.217
lymphocyte activation involved in immune response GO:0002285 93 0.214
cellular response to drug GO:0035690 15 0.214
regulation of inflammatory response GO:0050727 147 0.213
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.209
regulation of vesicle mediated transport GO:0060627 139 0.208
lymphocyte differentiation GO:0030098 242 0.205
lymphocyte costimulation GO:0031294 15 0.203
negative regulation of growth GO:0045926 99 0.200
Mouse
regulation of immunological synapse formation GO:2000520 2 0.196
innate immune response activating signal transduction GO:0002758 50 0.192
regulation of hematopoietic stem cell migration GO:2000471 1 0.191
eosinophil activation involved in immune response GO:0002278 1 0.184
cell recognition GO:0008037 83 0.182
mapk cascade GO:0000165 281 0.182
regulation of cell migration GO:0030334 219 0.181
eosinophil migration GO:0072677 3 0.180
regulation of cellular amine metabolic process GO:0033238 20 0.177
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.176
t cell activation GO:0042110 289 0.169
regulation of t cell extravasation GO:2000407 3 0.169
regulation of eosinophil degranulation GO:0043309 1 0.168
positive regulation of tumor necrosis factor production GO:0032760 30 0.168
t cell proliferation GO:0042098 120 0.164
positive regulation of cellular amine metabolic process GO:0033240 5 0.164
regulation of t cell costimulation GO:2000523 2 0.161
cytokine secretion GO:0050663 72 0.161
chemokine mediated signaling pathway GO:0070098 17 0.160
regulation of adaptive immune response GO:0002819 90 0.158
regulation of regulated secretory pathway GO:1903305 20 0.157
leukocyte migration GO:0050900 124 0.153
cellular response to acid chemical GO:0071229 68 0.152
adaptive immune response GO:0002250 155 0.152
Mouse
cellular amine metabolic process GO:0044106 44 0.150
apoptotic signaling pathway GO:0097190 306 0.149
Mouse
sequestering of metal ion GO:0051238 19 0.149
negative regulation of immune system process GO:0002683 209 0.148
regulation of ion homeostasis GO:2000021 64 0.148
divalent inorganic cation homeostasis GO:0072507 138 0.147
cellular ketone metabolic process GO:0042180 84 0.146
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.146
single organism cell adhesion GO:0098602 156 0.145
t cell migration GO:0072678 19 0.145
glycoprotein biosynthetic process GO:0009101 89 0.144
regulation of cytokine secretion GO:0050707 61 0.143
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.143
metal ion homeostasis GO:0055065 189 0.141
tumor necrosis factor production GO:0032640 50 0.138
lymphocyte proliferation GO:0046651 164 0.138
microglial cell activation involved in immune response GO:0002282 1 0.137
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.136
positive regulation of mapk cascade GO:0043410 170 0.135
carbohydrate derivative biosynthetic process GO:1901137 183 0.131
immune complex clearance GO:0002434 2 0.127
epithelial cell proliferation GO:0050673 174 0.127
cell adhesion GO:0007155 329 0.126
blood vessel morphogenesis GO:0048514 285 0.126
monocyte extravasation GO:0035696 2 0.124
myeloid leukocyte mediated immunity GO:0002444 42 0.124
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.122
calcium ion homeostasis GO:0055074 127 0.121
purine containing compound metabolic process GO:0072521 311 0.120
regulation of dendritic cell chemotaxis GO:2000508 1 0.119
leukocyte degranulation GO:0043299 27 0.118
regulation of lymphocyte proliferation GO:0050670 117 0.118
morphogenesis of a branching epithelium GO:0061138 193 0.118
membrane organization GO:0061024 245 0.118
glycoprotein metabolic process GO:0009100 116 0.117
cation homeostasis GO:0055080 212 0.117
corticotropin releasing hormone secretion GO:0043396 2 0.117
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526 1 0.115
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.115
amine metabolic process GO:0009308 45 0.115
negative regulation of defense response GO:0031348 77 0.115
positive regulation of chemotaxis GO:0050921 38 0.114
immunoglobulin production GO:0002377 73 0.113
positive regulation of monocyte extravasation GO:2000439 1 0.112
lymphocyte migration GO:0072676 26 0.111
alpha beta t cell activation involved in immune response GO:0002287 31 0.111
regulation of homeostatic process GO:0032844 182 0.108
myeloid leukocyte migration GO:0097529 57 0.107
regulation of acute inflammatory response GO:0002673 27 0.107
b cell activation involved in immune response GO:0002312 50 0.106
alpha beta t cell proliferation GO:0046633 21 0.105
detection of other organism GO:0098543 8 0.105
positive regulation of adaptive immune response GO:0002821 61 0.104
activation of immune response GO:0002253 138 0.101
regulation of endocytosis GO:0030100 69 0.099
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.098
regulation of t cell proliferation GO:0042129 92 0.098
cation transport GO:0006812 399 0.097
b cell activation GO:0042113 161 0.097
divalent inorganic cation transport GO:0072511 178 0.096
alpha beta t cell differentiation GO:0046632 69 0.095
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.094
immune complex clearance by monocytes and macrophages GO:0002436 2 0.094
regulation of alpha beta t cell activation GO:0046634 53 0.093
neuronal action potential GO:0019228 54 0.093
ras protein signal transduction GO:0007265 77 0.092
regulation of kinase activity GO:0043549 249 0.091
muscle tissue development GO:0060537 308 0.090
regulation of phagocytosis GO:0050764 33 0.090
positive regulation of b cell activation GO:0050871 49 0.089
negative regulation of immune effector process GO:0002698 55 0.089
maintenance of location GO:0051235 89 0.089
nucleobase containing small molecule metabolic process GO:0055086 352 0.088
positive regulation of alpha beta t cell activation GO:0046635 39 0.088
regulation of protein localization GO:0032880 231 0.087
morphogenesis of a branching structure GO:0001763 203 0.087
regulation of leukocyte proliferation GO:0070663 121 0.087
regulation of immunoglobulin production GO:0002637 42 0.087
angiogenesis GO:0001525 201 0.086
regulation of angiogenesis GO:0045765 81 0.084
positive regulation of response to wounding GO:1903036 66 0.084
purine ribonucleoside metabolic process GO:0046128 241 0.083
regulation of cellular amino acid metabolic process GO:0006521 5 0.082
regulation of cellular ketone metabolic process GO:0010565 66 0.082
leukocyte chemotaxis GO:0030595 69 0.082
organonitrogen compound catabolic process GO:1901565 264 0.081
regulation of eosinophil migration GO:2000416 2 0.080
positive regulation of endocytosis GO:0045807 42 0.080
cellular amino acid metabolic process GO:0006520 103 0.080
transmission of nerve impulse GO:0019226 76 0.079
positive regulation of secretion GO:0051047 130 0.078
granzyme mediated apoptotic signaling pathway GO:0008626 1 0.078
Mouse
cellular ion homeostasis GO:0006873 165 0.078
neutrophil migration GO:1990266 37 0.077
positive regulation of hematopoietic stem cell migration GO:2000473 1 0.077
positive regulation of leukocyte differentiation GO:1902107 86 0.077
interleukin 1 production GO:0032612 31 0.076
modulation of growth of symbiont involved in interaction with host GO:0044144 19 0.076
Mouse
cell cell recognition GO:0009988 44 0.075
t cell costimulation GO:0031295 14 0.075
positive regulation of lymphocyte migration GO:2000403 11 0.075
myotube differentiation GO:0014902 105 0.074
microglial cell activation GO:0001774 3 0.074
granulocyte chemotaxis GO:0071621 39 0.073
positive regulation of immunological synapse formation GO:2000522 1 0.073
negative regulation of homeostatic process GO:0032845 71 0.073
growth of symbiont involved in interaction with host GO:0044116 23 0.073
Mouse
ribonucleoside metabolic process GO:0009119 245 0.072
regulation of interleukin 1 secretion GO:0050704 15 0.072
positive regulation of granulocyte chemotaxis GO:0071624 12 0.072
endocytosis GO:0006897 168 0.072
ribose phosphate metabolic process GO:0019693 291 0.071
organic cyclic compound catabolic process GO:1901361 295 0.070
regulation of cell motility GO:2000145 236 0.070
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.070
Mouse
regulation of mapk cascade GO:0043408 248 0.070
muscle cell differentiation GO:0042692 261 0.070
second messenger mediated signaling GO:0019932 73 0.070
regulation of establishment of protein localization GO:0070201 181 0.069
positive regulation of behavior GO:0048520 40 0.069
eosinophil mediated immunity GO:0002447 1 0.068
small gtpase mediated signal transduction GO:0007264 97 0.068
positive regulation of striated muscle cell differentiation GO:0051155 35 0.068
dendritic cell differentiation GO:0097028 26 0.068
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.068
negative regulation of phosphorus metabolic process GO:0010563 184 0.068
branching morphogenesis of an epithelial tube GO:0048754 159 0.068
regulation of interleukin 2 production GO:0032663 28 0.068
multicellular organismal signaling GO:0035637 91 0.067
gliogenesis GO:0042063 141 0.066
regulation of membrane potential GO:0042391 192 0.066
peptidyl amino acid modification GO:0018193 336 0.065
regulation of muscle tissue development GO:1901861 97 0.065
regulation of b cell activation GO:0050864 81 0.065
positive regulation of epithelial cell proliferation GO:0050679 68 0.065
activation of mapk activity GO:0000187 59 0.065
cellular nitrogen compound catabolic process GO:0044270 280 0.064
regulation of growth of symbiont in host GO:0044126 19 0.064
Mouse
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.063
t cell differentiation involved in immune response GO:0002292 30 0.063
guanosine containing compound metabolic process GO:1901068 144 0.063
antigen receptor mediated signaling pathway GO:0050851 64 0.062
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.062
positive regulation of eosinophil migration GO:2000418 2 0.061
extrinsic apoptotic signaling pathway GO:0097191 126 0.061
regulation of map kinase activity GO:0043405 120 0.060
release of sequestered calcium ion into cytosol GO:0051209 42 0.060
nucleoside metabolic process GO:0009116 246 0.060
myeloid cell differentiation GO:0030099 233 0.060
cellular metal ion homeostasis GO:0006875 151 0.060
cellular extravasation GO:0045123 17 0.060
nitric oxide biosynthetic process GO:0006809 25 0.060
ribonucleoside catabolic process GO:0042454 206 0.060
regulation of protein serine threonine kinase activity GO:0071900 157 0.059
regulation of monocyte extravasation GO:2000437 2 0.059
negative regulation of growth of symbiont in host GO:0044130 19 0.059
Mouse
nucleoside catabolic process GO:0009164 206 0.059
nucleoside phosphate metabolic process GO:0006753 338 0.059
response to drug GO:0042493 75 0.059
interleukin 1 beta secretion GO:0050702 16 0.058
regulation of secretion GO:0051046 274 0.058
ribonucleotide metabolic process GO:0009259 291 0.058
neuron migration GO:0001764 122 0.058
divalent metal ion transport GO:0070838 172 0.058
cellular calcium ion homeostasis GO:0006874 119 0.057
positive regulation of t cell migration GO:2000406 10 0.057
positive regulation of t cell chemotaxis GO:0010820 5 0.057
action potential GO:0001508 78 0.057
purine nucleoside metabolic process GO:0042278 241 0.057
positive regulation of phagocytosis GO:0050766 26 0.056
carbohydrate derivative catabolic process GO:1901136 231 0.056
positive regulation of acute inflammatory response GO:0002675 16 0.056
myeloid leukocyte differentiation GO:0002573 119 0.056
cytosolic calcium ion homeostasis GO:0051480 70 0.056
activation of innate immune response GO:0002218 56 0.055
interleukin 2 production GO:0032623 33 0.055
defense response to gram positive bacterium GO:0050830 50 0.055
Mouse
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.055
nucleotide metabolic process GO:0009117 332 0.055
myeloid cell apoptotic process GO:0033028 22 0.055
regulation of hydrolase activity GO:0051336 246 0.054
cellular response to growth factor stimulus GO:0071363 197 0.054
positive regulation of protein modification process GO:0031401 299 0.054
interleukin 1 beta production GO:0032611 30 0.053
regulation of protein kinase activity GO:0045859 232 0.053
t helper 17 cell chemotaxis GO:0035705 1 0.053
acute inflammatory response GO:0002526 41 0.053
aromatic compound catabolic process GO:0019439 286 0.053
regulation of nucleotide metabolic process GO:0006140 169 0.052
dna metabolic process GO:0006259 303 0.052
t helper 1 type immune response GO:0042088 25 0.052
striated muscle tissue development GO:0014706 293 0.052
positive regulation of cell motility GO:2000147 116 0.052
leukocyte apoptotic process GO:0071887 71 0.051
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.051
response to acid chemical GO:0001101 111 0.051
dna recombination GO:0006310 92 0.051
signal transduction in absence of ligand GO:0038034 55 0.051
muscle cell development GO:0055001 133 0.051
regulation of chemotaxis GO:0050920 53 0.051
thymocyte migration GO:0072679 2 0.051
positive regulation of map kinase activity GO:0043406 84 0.051
positive regulation of dendritic cell chemotaxis GO:2000510 1 0.050
interleukin 1 secretion GO:0050701 16 0.050
growth involved in symbiotic interaction GO:0044110 23 0.050
Mouse
regulation of exocytosis GO:0017157 61 0.050
regulation of response to wounding GO:1903034 189 0.050
positive regulation of hydrolase activity GO:0051345 148 0.050
regulation of cellular catabolic process GO:0031329 242 0.050
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.050
plasma membrane organization GO:0007009 90 0.050
regulation of immune complex clearance by monocytes and macrophages GO:0090264 2 0.049
positive regulation of apoptotic process GO:0043065 217 0.049
positive regulation of inflammatory response to antigenic stimulus GO:0002863 11 0.049
positive regulation of programmed cell death GO:0043068 218 0.049
gtp metabolic process GO:0046039 144 0.049
pattern recognition receptor signaling pathway GO:0002221 47 0.048
regulation of cellular response to stress GO:0080135 159 0.048
interspecies interaction between organisms GO:0044419 83 0.048
Mouse
epithelial tube morphogenesis GO:0060562 303 0.048
regulation of ras protein signal transduction GO:0046578 114 0.048
regulation of cytokine biosynthetic process GO:0042035 59 0.048
cellular homeostasis GO:0019725 240 0.047
mammary gland epithelium development GO:0061180 65 0.047
positive regulation of nitric oxide biosynthetic process GO:0045429 14 0.047
regulation of protein transport GO:0051223 163 0.046
cd4 positive alpha beta t cell activation GO:0035710 45 0.046
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.046
rho protein signal transduction GO:0007266 32 0.046
negative regulation of apoptotic signaling pathway GO:2001234 104 0.045
dendritic cell antigen processing and presentation GO:0002468 7 0.045
multicellular organismal homeostasis GO:0048871 164 0.045
negative regulation of inflammatory response GO:0050728 61 0.045
regulation of thymocyte migration GO:2000410 2 0.045
regulation of neutrophil chemotaxis GO:0090022 14 0.044
t cell extravasation GO:0072683 4 0.044
nucleoside triphosphate catabolic process GO:0009143 205 0.044
calcium ion transport GO:0006816 159 0.044
glycosyl compound catabolic process GO:1901658 206 0.044
cellular response to amino acid stimulus GO:0071230 29 0.044
response to growth factor GO:0070848 198 0.044
forebrain cell migration GO:0021885 58 0.044
positive regulation of gtpase activity GO:0043547 85 0.043
regulation of purine nucleotide metabolic process GO:1900542 169 0.043
positive regulation of glycoprotein metabolic process GO:1903020 6 0.043
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.043
blood circulation GO:0008015 195 0.043
Mouse
negative regulation of multi organism process GO:0043901 68 0.042
Mouse
macrophage apoptotic process GO:0071888 7 0.042
positive regulation of protein phosphorylation GO:0001934 242 0.042
positive regulation of kinase activity GO:0033674 155 0.041
inflammatory response to antigenic stimulus GO:0002437 30 0.041
embryonic placenta development GO:0001892 98 0.041
nitric oxide metabolic process GO:0046209 25 0.041
regulation of t cell differentiation GO:0045580 83 0.041
ameboidal type cell migration GO:0001667 128 0.041
regulation of interleukin 1 production GO:0032652 26 0.040
regulation of anatomical structure size GO:0090066 178 0.040
peptidyl tyrosine modification GO:0018212 145 0.040
regulation of multi organism process GO:0043900 111 0.040
Mouse
exocytosis GO:0006887 121 0.040
regulation of b cell proliferation GO:0030888 39 0.040
regulation of corticotropin releasing hormone secretion GO:0043397 2 0.040
nucleotide catabolic process GO:0009166 217 0.039
regulation of neutrophil migration GO:1902622 14 0.039
ribonucleoside triphosphate catabolic process GO:0009203 199 0.039
t cell receptor signaling pathway GO:0050852 46 0.039
cellular response to oxidative stress GO:0034599 76 0.039
regulation of nucleoside metabolic process GO:0009118 130 0.039
isotype switching GO:0045190 36 0.039
purine ribonucleotide metabolic process GO:0009150 290 0.039
regulation of t helper 1 type immune response GO:0002825 17 0.038
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.038
positive regulation of protein secretion GO:0050714 52 0.038
positive regulation of muscle cell differentiation GO:0051149 39 0.038
regulation of nitric oxide biosynthetic process GO:0045428 18 0.038
regulation of purine nucleotide catabolic process GO:0033121 122 0.037
positive regulation of b cell mediated immunity GO:0002714 26 0.037
positive regulation of cell death GO:0010942 224 0.037
tissue homeostasis GO:0001894 115 0.037
t cell chemotaxis GO:0010818 6 0.037
cellular response to molecule of fungal origin GO:0071226 2 0.037
cytoplasmic transport GO:0016482 234 0.037
myeloid cell activation involved in immune response GO:0002275 34 0.037
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.037
regulation of ion transport GO:0043269 215 0.037
response to oxidative stress GO:0006979 123 0.037
lymph node development GO:0048535 18 0.036
organophosphate catabolic process GO:0046434 232 0.036
membrane invagination GO:0010324 17 0.036
response to organonitrogen compound GO:0010243 246 0.036
positive regulation of alpha beta t cell proliferation GO:0046641 12 0.036
glycosyl compound metabolic process GO:1901657 246 0.036
positive regulation of interleukin 12 production GO:0032735 21 0.035
negative regulation of leukocyte apoptotic process GO:2000107 31 0.035
positive regulation of cell migration GO:0030335 109 0.035
response to interferon gamma GO:0034341 34 0.035
organic acid transport GO:0015849 101 0.035
hematopoietic stem cell migration GO:0035701 1 0.035
axon ensheathment GO:0008366 76 0.035
regulation of hormone levels GO:0010817 211 0.035
Mouse
visceral motor neuron differentiation GO:0021524 3 0.035
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.035
positive regulation of protein kinase activity GO:0045860 144 0.035
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.035
b cell proliferation GO:0042100 53 0.035
developmental growth involved in morphogenesis GO:0060560 138 0.034
negative regulation of innate immune response GO:0045824 17 0.034
positive regulation of immunoglobulin production GO:0002639 28 0.034
negative regulation of phosphate metabolic process GO:0045936 184 0.034
negative regulation of cellular component organization GO:0051129 194 0.034
negative regulation of myeloid cell apoptotic process GO:0033033 11 0.034
t cell mediated immunity GO:0002456 50 0.034
Mouse
somatic cell dna recombination GO:0016444 51 0.034
regulation of leukocyte apoptotic process GO:2000106 56 0.034
positive regulation of cell adhesion GO:0045785 80 0.034
response to yeast GO:0001878 6 0.034
gland development GO:0048732 330 0.034
lymphocyte apoptotic process GO:0070227 54 0.033
purine ribonucleoside catabolic process GO:0046130 205 0.032
neutrophil chemotaxis GO:0030593 36 0.032
muscle system process GO:0003012 141 0.032
protein kinase b signaling GO:0043491 74 0.032
purine nucleoside triphosphate metabolic process GO:0009144 226 0.032
regulation of rho protein signal transduction GO:0035023 71 0.032
nucleoside phosphate catabolic process GO:1901292 222 0.031
granulocyte migration GO:0097530 43 0.031
regulation of lymphocyte chemotaxis GO:1901623 6 0.031
purine nucleoside catabolic process GO:0006152 205 0.031
cellular response to interleukin 15 GO:0071350 2 0.031
mature natural killer cell chemotaxis GO:0035782 1 0.031
positive regulation of nucleotide metabolic process GO:0045981 114 0.031
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.031
antigen processing and presentation GO:0019882 47 0.031
myeloid leukocyte activation GO:0002274 83 0.030
intrinsic apoptotic signaling pathway in response to osmotic stress GO:0008627 2 0.030
regulation of production of molecular mediator of immune response GO:0002700 65 0.030
regulation of nucleotide catabolic process GO:0030811 122 0.030
regulation of cell adhesion GO:0030155 154 0.030
regulation of interleukin 6 production GO:0032675 55 0.030
receptor mediated endocytosis GO:0006898 51 0.030
cyclic nucleotide metabolic process GO:0009187 59 0.030
positive regulation of t cell extravasation GO:2000409 2 0.029
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.029
anatomical structure homeostasis GO:0060249 145 0.029
carbohydrate metabolic process GO:0005975 230 0.029
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.029
organophosphate biosynthetic process GO:0090407 122 0.029
regulation of intracellular transport GO:0032386 159 0.029
positive regulation of camp mediated signaling GO:0043950 3 0.029
skeletal muscle organ development GO:0060538 163 0.029
cellular divalent inorganic cation homeostasis GO:0072503 127 0.029
regulation of transferase activity GO:0051338 263 0.029
developmental maturation GO:0021700 193 0.029
cytokine production involved in immune response GO:0002367 34 0.029
regulation of systemic arterial blood pressure GO:0003073 61 0.029
Mouse
response to transforming growth factor beta GO:0071559 88 0.029
sensory perception GO:0007600 245 0.029
t cell activation involved in immune response GO:0002286 43 0.029
regulation of acute inflammatory response to antigenic stimulus GO:0002864 10 0.028
peptidyl tyrosine phosphorylation GO:0018108 143 0.028
chemotaxis GO:0006935 247 0.028
microglia differentiation GO:0014004 2 0.028
regulation of interleukin 1 beta production GO:0032651 25 0.028

Gzmk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.141
musculoskeletal system disease DOID:17 0 0.141
connective tissue disease DOID:65 0 0.141