IMP

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Mus musculus

17 genes annotated in mouse

chemokine mediated signaling pathway

A series of molecular signals initiated by the binding of a chemokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "chemokine mediated signaling pathway"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "chemokine mediated signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
Robo1	roundabout homolog 1 (Drosophila)	0.999	Human
Ccr2	chemokine (C-C motif) receptor 2	0.995
Ccl2	chemokine (C-C motif) ligand 2	0.940
Slit3	slit homolog 3 (Drosophila)	0.938	Human
Robo2	roundabout homolog 2 (Drosophila)	0.925
Ccr5	chemokine (C-C motif) receptor 5	0.890
Cd44	CD44 antigen	0.857
Ifng	interferon gamma	0.838
Slit2	slit homolog 2 (Drosophila)	0.806	Human
Ccl3	chemokine (C-C motif) ligand 3	0.760
Mmp9	matrix metallopeptidase 9	0.625
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.519
Cd7	CD7 antigen	0.495
Cd180	CD180 antigen	0.478
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.457
Tlr4	toll-like receptor 4	0.451
Fasl	Fas ligand (TNF superfamily, member 6)	0.406
Ccr6	chemokine (C-C motif) receptor 6	0.403	Mouse
Tlr2	toll-like receptor 2	0.373
Itgax	integrin alpha X	0.358
Selp	selectin, platelet	0.276
Nrp1	neuropilin 1	0.253
Ctsw	cathepsin W	0.250
Prdm1	PR domain containing 1, with ZNF domain	0.246
Oxt	oxytocin	0.237
Ciita	class II transactivator	0.224
Spib	Spi-B transcription factor (Spi-1/PU.1 related)	0.211
Fcrla	Fc receptor-like A	0.207
Cd96	CD96 antigen	0.189
Fcer2a	Fc receptor, IgE, low affinity II, alpha polypeptide	0.186
Cd2	CD2 antigen	0.183
Itgal	integrin alpha L	0.177
Blk	B lymphoid kinase	0.170
Il18rap	interleukin 18 receptor accessory protein	0.167
Itk	IL2-inducible T-cell kinase	0.166
Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	0.164
Gzmk	granzyme K	0.160
Gzma	granzyme A	0.156
Klrg1	killer cell lectin-like receptor subfamily G, member 1	0.155
Xcr1	chemokine (C motif) receptor 1	0.146	Mouse
Icam1	intercellular adhesion molecule 1	0.142
Il10	interleukin 10	0.141
Il18r1	interleukin 18 receptor 1	0.141
Gzmb	granzyme B	0.133
Flt3	FMS-like tyrosine kinase 3	0.126
Cxcr3	chemokine (C-X-C motif) receptor 3	0.125	Mouse Rat
Klra5	killer cell lectin-like receptor, subfamily A, member 5	0.117
Lyz2	lysozyme 2	0.112
Cd6	CD6 antigen	0.108
Asap1	ArfGAP with SH# domain, ankyrin repeat and PH domain1	0.107
Il27ra	interleukin 27 receptor, alpha	0.103
S1pr4	sphingosine-1-phosphate receptor 4	0.103
Ms4a1	membrane-spanning 4-domains, subfamily A, member 1	0.101
Abp1	amiloride binding protein 1 (amine oxidase, copper-containing)	0.097
Il2rb	interleukin 2 receptor, beta chain	0.095
Src	Rous sarcoma oncogene	0.095
H2-Ob	histocompatibility 2, O region beta locus	0.094
Spn	sialophorin	0.092
Ccr1	chemokine (C-C motif) receptor 1	0.091
Spp1	secreted phosphoprotein 1	0.091
Cx3cr1	chemokine (C-X3-C) receptor 1	0.090	Mouse Rat
Gpr132	G protein-coupled receptor 132	0.088
Bcar1	breast cancer anti-estrogen resistance 1	0.086
Ncr1	natural cytotoxicity triggering receptor 1	0.080
Nos1	nitric oxide synthase 1, neuronal	0.079
Ly6d	lymphocyte antigen 6 complex, locus D	0.077
Tff1	trefoil factor 1	0.076	Mouse
Il1r1	interleukin 1 receptor, type I	0.076
Sh2d2a	SH2 domain protein 2A	0.076
Elf4	E74-like factor 4 (ets domain transcription factor)	0.075
Klrc1	killer cell lectin-like receptor subfamily C, member 1	0.075
Cd3e	CD3 antigen, epsilon polypeptide	0.075
Prg3	proteoglycan 3	0.070
Slit1	slit homolog 1 (Drosophila)	0.063
Il1rn	interleukin 1 receptor antagonist	0.062
Rgs14	regulator of G-protein signaling 14	0.062
Gimap7	GTPase, IMAP family member 7	0.061
Nkg7	natural killer cell group 7 sequence	0.059
Igj	immunoglobulin joining chain	0.058
Muc13	mucin 13, epithelial transmembrane	0.057
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.057
H2-Oa	histocompatibility 2, O region alpha locus	0.056
Fgd3	FYVE, RhoGEF and PH domain containing 3	0.054
Tbx21	T-box 21	0.052
Nos2	nitric oxide synthase 2, inducible	0.052
Sit1	suppression inducing transmembrane adaptor 1	0.052
Ccl4	chemokine (C-C motif) ligand 4	0.051
Il1b	interleukin 1 beta	0.051
Cxcr2	chemokine (C-X-C motif) receptor 2	0.051
Itgb7	integrin beta 7	0.050
Cd8a	CD8 antigen, alpha chain	0.049
Csf1	colony stimulating factor 1 (macrophage)	0.048
Cxcr4	chemokine (C-X-C motif) receptor 4	0.048	Mouse Rat
Klra9	killer cell lectin-like receptor subfamily A, member 9	0.048
Olfr140	olfactory receptor 140	0.047
Cd5	CD5 antigen	0.046
Ltb	lymphotoxin B	0.046
H2-Eb1	histocompatibility 2, class II antigen E beta	0.046
Cxcr6	chemokine (C-X-C motif) receptor 6	0.045
Il10ra	interleukin 10 receptor, alpha	0.045
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.044
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.043
Cxcl13	chemokine (C-X-C motif) ligand 13	0.043
Cd3g	CD3 antigen, gamma polypeptide	0.043
Ifngr1	interferon gamma receptor 1	0.042
Cd3d	CD3 antigen, delta polypeptide	0.042
Ubd	ubiquitin D	0.041
Sell	selectin, lymphocyte	0.041
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.040
Lepr	leptin receptor	0.040
Klrb1c	killer cell lectin-like receptor subfamily B member 1C	0.040
Slfn1	schlafen 1	0.040
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.037
Dmbt1	deleted in malignant brain tumors 1	0.036
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.036
H2-Ab1	histocompatibility 2, class II antigen A, beta 1	0.035
Tnfsf8	tumor necrosis factor (ligand) superfamily, member 8	0.035
Gimap3	GTPase, IMAP family member 3	0.034
Art2a-ps	ADP-ribosyltransferase 2a, pseudogene	0.034
Pyhin1	pyrin and HIN domain family, member 1	0.033
Tnf	tumor necrosis factor	0.033
Cd22	CD22 antigen	0.033
Ldlr	low density lipoprotein receptor	0.032
2210010C04Rik	RIKEN cDNA 2210010C04 gene	0.032
Galnt6	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6	0.032
Pik3cg	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.031
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.031
Rgs9	regulator of G-protein signaling 9	0.030
Tnfsf10	tumor necrosis factor (ligand) superfamily, member 10	0.030
Reg3g	regenerating islet-derived 3 gamma	0.029
Foxp3	forkhead box P3	0.029
Gbp1	guanylate binding protein 1	0.028
Itgae	integrin alpha E, epithelial-associated	0.028
Apoe	apolipoprotein E	0.028
Cd8b1	CD8 antigen, beta chain 1	0.028
Mcpt1	mast cell protease 1	0.028
Havcr2	hepatitis A virus cellular receptor 2	0.027
Ngp	neutrophilic granule protein	0.027
Bdkrb1	bradykinin receptor, beta 1	0.027
Krtap3-1	keratin associated protein 3-1	0.026
Il7r	interleukin 7 receptor	0.026
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.025
Sfpi1	SFFV proviral integration 1	0.025
Ptprc	protein tyrosine phosphatase, receptor type, C	0.024
Elk4	ELK4, member of ETS oncogene family	0.023
Ccr1l1	chemokine (C-C motif) receptor 1-like 1	0.023	Human Mouse
Txk	TXK tyrosine kinase	0.023
Myo1f	myosin IF	0.023
Ikzf1	IKAROS family zinc finger 1	0.023
Il1rl1	interleukin 1 receptor-like 1	0.023
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.023
Itga4	integrin alpha 4	0.023
Fpr3	formyl peptide receptor 3	0.023
Ptgir	prostaglandin I receptor (IP)	0.022
Dock2	dedicator of cyto-kinesis 2	0.022
Cxcl9	chemokine (C-X-C motif) ligand 9	0.022
Ccr3	chemokine (C-C motif) receptor 3	0.022
Hr	hairless	0.022
Rasgrp1	RAS guanyl releasing protein 1	0.022
Myd88	myeloid differentiation primary response gene 88	0.022
Itgam	integrin alpha M	0.022
Cd40	CD40 antigen	0.022
Itga2	integrin alpha 2	0.022
Grem2	gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis)	0.021
Pla2g2d	phospholipase A2, group IID	0.021
Retnlb	resistin like beta	0.021
Sele	selectin, endothelial cell	0.021
Kap	kidney androgen regulated protein	0.020
Il12rb2	interleukin 12 receptor, beta 2	0.020
Irf5	interferon regulatory factor 5	0.020
Lgals2	lectin, galactose-binding, soluble 2	0.020
H2-DMb2	histocompatibility 2, class II, locus Mb2	0.020
H2-Aa	histocompatibility 2, class II antigen A, alpha	0.020
Cxcl12	chemokine (C-X-C motif) ligand 12	0.019	Human
Cst7	cystatin F (leukocystatin)	0.019
St6galnac1	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1	0.019
Cdhr5	cadherin-related family member 5	0.019
Ctrb1	chymotrypsinogen B1	0.019
Pdcd1	programmed cell death 1	0.019
Tspo2	translocator protein 2	0.019
Ltf	lactotransferrin	0.019
Cel	carboxyl ester lipase	0.019
Il12a	interleukin 12a	0.019
Gimap4	GTPase, IMAP family member 4	0.019
Gdf10	growth differentiation factor 10	0.018
Gpr18	G protein-coupled receptor 18	0.018
Rasal1	RAS protein activator like 1 (GAP1 like)	0.018
Slamf6	SLAM family member 6	0.018
Arl10	ADP-ribosylation factor-like 10	0.018
Wisp2	WNT1 inducible signaling pathway protein 2	0.018
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.018
LOC100502924	hypothetical protein LOC100502924	0.018
Cd86	CD86 antigen	0.018
Cybb	cytochrome b-245, beta polypeptide	0.018
Ear2	eosinophil-associated, ribonuclease A family, member 2	0.018
Il16	interleukin 16	0.017
Slfn4	schlafen 4	0.017
Fgf7	fibroblast growth factor 7	0.017
Gcet2	germinal center expressed transcript 2	0.017
Gp2	glycoprotein 2 (zymogen granule membrane)	0.017
Il1a	interleukin 1 alpha	0.017
Cytip	cytohesin 1 interacting protein	0.017
Abcg3	ATP-binding cassette, sub-family G (WHITE), member 3	0.017
Aoah	acyloxyacyl hydrolase	0.017
Fmo3	flavin containing monooxygenase 3	0.017
Gna15	guanine nucleotide binding protein, alpha 15	0.017
Fpr-rs3	formyl peptide receptor, related sequence 3	0.017
Ptgs2	prostaglandin-endoperoxide synthase 2	0.017
Pxn	paxillin	0.017
Ccl5	chemokine (C-C motif) ligand 5	0.017	Human
Xcl1	chemokine (C motif) ligand 1	0.017
Prss30	protease, serine, 30	0.016
Adamdec1	ADAM-like, decysin 1	0.016
Ccl17	chemokine (C-C motif) ligand 17	0.016
Hrh1	histamine receptor H1	0.016
Ccl20	chemokine (C-C motif) ligand 20	0.016
Chad	chondroadherin	0.016
Cd79a	CD79A antigen (immunoglobulin-associated alpha)	0.016
Ins1	insulin I	0.016
Lcn4	lipocalin 4	0.016
Asprv1	aspartic peptidase, retroviral-like 1	0.016
Slamf1	signaling lymphocytic activation molecule family member 1	0.016
Grem1	gremlin 1	0.016
L1cam	L1 cell adhesion molecule	0.016
Fat4	FAT tumor suppressor homolog 4 (Drosophila)	0.016
Cr2	complement receptor 2	0.015
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.015
Prkce	protein kinase C, epsilon	0.015
Vpreb3	pre-B lymphocyte gene 3	0.015
Il4	interleukin 4	0.015
Cela2a	chymotrypsin-like elastase family, member 2A	0.015
Selplg	selectin, platelet (p-selectin) ligand	0.015
Il6	interleukin 6	0.015
Reg1	regenerating islet-derived 1	0.015
Il9r	interleukin 9 receptor	0.015
Rab25	RAB25, member RAS oncogene family	0.015
Capn3	calpain 3	0.015
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.015
Lta	lymphotoxin A	0.015
Cd207	CD207 antigen	0.015
Il15	interleukin 15	0.015
Runx1	runt related transcription factor 1	0.015
Cd14	CD14 antigen	0.014
Mep1a	meprin 1 alpha	0.014
Cnga1	cyclic nucleotide gated channel alpha 1	0.014
Cd244	CD244 natural killer cell receptor 2B4	0.014
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.014
Ms4a6c	membrane-spanning 4-domains, subfamily A, member 6C	0.014
Clec2i	C-type lectin domain family 2, member i	0.014
U46068	cDNA sequence U46068	0.014
Avp	arginine vasopressin	0.014
Cxcl10	chemokine (C-X-C motif) ligand 10	0.014	Human
P2rx1	purinergic receptor P2X, ligand-gated ion channel, 1	0.014
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.014
Gcnt1	glucosaminyl (N-acetyl) transferase 1, core 2	0.014
Bex6	brain expressed gene 6	0.014
Cfc1	cripto, FRL-1, cryptic family 1	0.014
Cldn2	claudin 2	0.013
Sytl3	synaptotagmin-like 3	0.013
Il2ra	interleukin 2 receptor, alpha chain	0.013
Cd74	CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)	0.013
Cd4	CD4 antigen	0.013
Stat4	signal transducer and activator of transcription 4	0.013
Fcrl1	Fc receptor-like 1	0.013
H2-Eb2	histocompatibility 2, class II antigen E beta2	0.013
Fyn	Fyn proto-oncogene	0.013
Dnahc5	dynein, axonemal, heavy chain 5	0.013
Fam65b	family with sequence similarity 65, member B	0.013
Prl4a1	prolactin family 4, subfamily a, member 1	0.013
Matk	megakaryocyte-associated tyrosine kinase	0.013
Chst3	carbohydrate (chondroitin 6/keratan) sulfotransferase 3	0.013
Htr3a	5-hydroxytryptamine (serotonin) receptor 3A	0.013
Rab37	RAB37, member of RAS oncogene family	0.013
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.013
Tcstv3	2-cell-stage, variable group, member 3	0.013
Il2rg	interleukin 2 receptor, gamma chain	0.013
Aire	autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)	0.012
F2rl2	coagulation factor II (thrombin) receptor-like 2	0.012
Odz3	odd Oz/ten-m homolog 3 (Drosophila)	0.012
Ms4a2	membrane-spanning 4-domains, subfamily A, member 2	0.012
Mx2	myxovirus (influenza virus) resistance 2	0.012
Mcpt2	mast cell protease 2	0.012
Grin2a	glutamate receptor, ionotropic, NMDA2A (epsilon 1)	0.012
Mag	myelin-associated glycoprotein	0.012
Nt5e	5' nucleotidase, ecto	0.012
Smad3	MAD homolog 3 (Drosophila)	0.012
Stk4	serine/threonine kinase 4	0.012
Ccl8	chemokine (C-C motif) ligand 8	0.012
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.012
Gpr33	G protein-coupled receptor 33	0.012
Pkib	protein kinase inhibitor beta, cAMP dependent, testis specific	0.012
Cd28	CD28 antigen	0.012
Krt20	keratin 20	0.012
Rasal3	RAS protein activator like 3	0.012
Scgb1a1	secretoglobin, family 1A, member 1 (uteroglobin)	0.012
Prkcb	protein kinase C, beta	0.012
Vcam1	vascular cell adhesion molecule 1	0.012
Slc34a1	solute carrier family 34 (sodium phosphate), member 1	0.012
Hmox1	heme oxygenase (decycling) 1	0.012
Gpr182	G protein-coupled receptor 182	0.012
Kcna3	potassium voltage-gated channel, shaker-related subfamily, member 3	0.012
Tssk1	testis-specific serine kinase 1	0.012
Zp2	zona pellucida glycoprotein 2	0.012
Cysltr2	cysteinyl leukotriene receptor 2	0.012
Clps	colipase, pancreatic	0.012
Soat2	sterol O-acyltransferase 2	0.012
Slc6a2	solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2	0.012
Pglyrp1	peptidoglycan recognition protein 1	0.012
Retn	resistin	0.012
Fcgbp	Fc fragment of IgG binding protein	0.012
Nlrp3	NLR family, pyrin domain containing 3	0.012
Lep	leptin	0.012
Isg20	interferon-stimulated protein	0.011
Tgfa	transforming growth factor alpha	0.011
Mmp8	matrix metallopeptidase 8	0.011
Tox	thymocyte selection-associated high mobility group box	0.011
C3ar1	complement component 3a receptor 1	0.011
Met	met proto-oncogene	0.011
Nfe2	nuclear factor, erythroid derived 2	0.011
Cbl	Casitas B-lineage lymphoma	0.011
Fut1	fucosyltransferase 1	0.011
Cacna1b	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.011
Tcl1b1	T-cell leukemia/lymphoma 1B, 1	0.011
Opn1sw	opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)	0.011
Ptgfr	prostaglandin F receptor	0.011
Cdh11	cadherin 11	0.011
Pdcd1lg2	programmed cell death 1 ligand 2	0.011
Prss2	protease, serine, 2	0.011
Ido1	indoleamine 2,3-dioxygenase 1	0.011
Dusp2	dual specificity phosphatase 2	0.011
Fn1	fibronectin 1	0.011
Calm4	calmodulin 4	0.011
Nckap1l	NCK associated protein 1 like	0.011
Avil	advillin	0.011
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.011
Sema4f	sema domain, immunoglobulin domain (Ig), TM domain, and short cytoplasmic domain	0.011
Uts2r	urotensin 2 receptor	0.011
Figf	c-fos induced growth factor	0.011
Slc30a3	solute carrier family 30 (zinc transporter), member 3	0.011
Agap2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	0.011
Vnn3	vanin 3	0.011
Cnr2	cannabinoid receptor 2 (macrophage)	0.010
Mc2r	melanocortin 2 receptor	0.010
Tff2	trefoil factor 2 (spasmolytic protein 1)	0.010
Cmah	cytidine monophospho-N-acetylneuraminic acid hydroxylase	0.010
Ptpre	protein tyrosine phosphatase, receptor type, E	0.010
Kmo	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	0.010
Tnfrsf18	tumor necrosis factor receptor superfamily, member 18	0.010
Gp9	glycoprotein 9 (platelet)	0.010
Mx1	myxovirus (influenza virus) resistance 1	0.010
Nat8	N-acetyltransferase 8 (GCN5-related, putative)	0.010
Edn3	endothelin 3	0.010
Dnase1l3	deoxyribonuclease 1-like 3	0.010
Mcart6	mitochondrial carrier triple repeat 6	0.010
Serping1	serine (or cysteine) peptidase inhibitor, clade G, member 1	0.010
Cd209a	CD209a antigen	0.010
Fpr1	formyl peptide receptor 1	0.010
Mmp12	matrix metallopeptidase 12	0.010
Prf1	perforin 1 (pore forming protein)	0.010
Ceacam2	carcinoembryonic antigen-related cell adhesion molecule 2	0.010
Scn1b	sodium channel, voltage-gated, type I, beta	0.010