Mus musculus

213 known processes

Hmgb1

high mobility group box 1

(Aliases: amphoterin,MGC117896,MGC117897,MGC103169,MGC103168,SBP-1,p30,HMG-1,Hmg1,DEF)

Hmgb1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
apoptotic signaling pathway GO:0097190 306 0.786
Mouse
cellular response to dna damage stimulus GO:0006974 207 0.756
dna metabolic process GO:0006259 303 0.740
male gamete generation GO:0048232 285 0.734
Mouse
spermatid development GO:0007286 108 0.659
Mouse
cellular glucan metabolic process GO:0006073 32 0.617
oxidation reduction process GO:0055114 342 0.607
meiotic nuclear division GO:0007126 115 0.571
glucan metabolic process GO:0044042 32 0.569
regulation of mitotic cell cycle GO:0007346 126 0.528
3 utr mediated mrna stabilization GO:0070935 2 0.526
gene silencing GO:0016458 38 0.476
regulation of glycogen catabolic process GO:0005981 2 0.472
regionalization GO:0003002 337 0.438
cellular polysaccharide catabolic process GO:0044247 5 0.425
chromatin modification GO:0016568 187 0.421
regulation of cell cycle process GO:0010564 160 0.404
regulation of organelle organization GO:0033043 289 0.392
regulation of rna splicing GO:0043484 37 0.379
positive regulation of glycogen catabolic process GO:0045819 2 0.353
polysaccharide metabolic process GO:0005976 39 0.341
regulation of chromosome organization GO:0033044 83 0.338
negative regulation of rna splicing GO:0033119 12 0.326
dna repair GO:0006281 107 0.320
regulation of cell cycle GO:0051726 281 0.318
mitotic cell cycle process GO:1903047 159 0.289
negative regulation of apoptotic cell clearance GO:2000426 1 0.276
stem cell maintenance GO:0019827 130 0.269
spermatogenesis GO:0007283 284 0.265
Mouse
organelle fission GO:0048285 170 0.254
negative regulation of cellular component organization GO:0051129 194 0.250
glucan catabolic process GO:0009251 5 0.240
germ cell development GO:0007281 185 0.236
Mouse
energy derivation by oxidation of organic compounds GO:0015980 77 0.234
spermatid differentiation GO:0048515 115 0.234
Mouse
development of primary sexual characteristics GO:0045137 143 0.233
Mouse
dna replication GO:0006260 52 0.233
lung development GO:0030324 164 0.233
negative regulation of protein metabolic process GO:0051248 282 0.231
negative regulation of cellular protein metabolic process GO:0032269 247 0.216
regulation of protein kinase activity GO:0045859 232 0.208
protein dna complex subunit organization GO:0071824 28 0.201
generation of precursor metabolites and energy GO:0006091 103 0.189
negative regulation of phagocytosis GO:0050765 4 0.183
protein localization to chromosome centromeric region GO:0071459 1 0.183
respiratory system development GO:0060541 190 0.182
response to radiation GO:0009314 165 0.175
female gamete generation GO:0007292 74 0.171
regulation of mitotic cell cycle phase transition GO:1901990 73 0.170
negative regulation of cell cycle GO:0045786 123 0.163
negative regulation of organelle organization GO:0010639 90 0.162
regulation of cellular amino acid metabolic process GO:0006521 5 0.161
cell fate commitment GO:0045165 210 0.158
cell cycle checkpoint GO:0000075 47 0.156
meiotic cell cycle GO:0051321 122 0.152
stem cell differentiation GO:0048863 268 0.150
cellular polysaccharide metabolic process GO:0044264 38 0.147
rna interference GO:0016246 2 0.146
heterocycle catabolic process GO:0046700 280 0.140
dendrite development GO:0016358 115 0.139
negative regulation of myeloid cell differentiation GO:0045638 38 0.138
Mouse
cellular amino acid metabolic process GO:0006520 103 0.136
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.133
Mouse
purine nucleotide catabolic process GO:0006195 211 0.133
glycogen catabolic process GO:0005980 5 0.131
cell junction organization GO:0034330 77 0.130
amine metabolic process GO:0009308 45 0.130
chromatin silencing GO:0006342 15 0.129
regulation of transferase activity GO:0051338 263 0.129
response to light stimulus GO:0009416 135 0.127
cellular amine metabolic process GO:0044106 44 0.123
nitrogen compound transport GO:0071705 271 0.122
small gtpase mediated signal transduction GO:0007264 97 0.122
meiotic cell cycle process GO:1903046 77 0.119
positive regulation of proteolysis GO:0045862 85 0.119
intrinsic apoptotic signaling pathway GO:0097193 132 0.119
segmentation GO:0035282 93 0.118
posttranscriptional gene silencing by rna GO:0035194 10 0.118
mitotic nuclear division GO:0007067 48 0.117
protein methylation GO:0006479 81 0.117
multicellular organism growth GO:0035264 161 0.115
chromatin organization GO:0006325 206 0.114
glycogen metabolic process GO:0005977 32 0.114
protein localization to organelle GO:0033365 185 0.113
nuclear transcribed mrna catabolic process GO:0000956 16 0.112
cellular ketone metabolic process GO:0042180 84 0.110
mrna stabilization GO:0048255 9 0.108
nucleosome positioning GO:0016584 4 0.103
regulation of nuclear division GO:0051783 56 0.101
cellular component assembly involved in morphogenesis GO:0010927 139 0.101
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.100
negative regulation of chromosome organization GO:2001251 30 0.099
histone modification GO:0016570 159 0.096
spliceosomal complex assembly GO:0000245 6 0.095
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.090
regulation of cellular amine metabolic process GO:0033238 20 0.089
chromosome segregation GO:0007059 48 0.088
negative regulation of molecular function GO:0044092 258 0.086
cell division GO:0051301 120 0.086
dna damage checkpoint GO:0000077 26 0.085
alternative mrna splicing via spliceosome GO:0000380 12 0.084
polysaccharide catabolic process GO:0000272 5 0.083
gonad development GO:0008406 141 0.083
Mouse
nucleotide excision repair GO:0006289 13 0.082
response to lipopolysaccharide GO:0032496 128 0.079
gene silencing by rna GO:0031047 19 0.078
regulation of proteolysis GO:0030162 164 0.078
negative regulation of b cell differentiation GO:0045578 4 0.077
Mouse
chromatin assembly GO:0031497 13 0.076
metaphase plate congression GO:0051310 2 0.074
stem cell development GO:0048864 219 0.073
energy reserve metabolic process GO:0006112 39 0.072
morphogenesis of embryonic epithelium GO:0016331 159 0.072
nucleotide metabolic process GO:0009117 332 0.071
negative regulation of cell activation GO:0050866 111 0.071
Mouse
mitotic cell cycle checkpoint GO:0007093 31 0.069
regulation of cellular ketone metabolic process GO:0010565 66 0.069
negative regulation of chromatin modification GO:1903309 19 0.068
development of primary male sexual characteristics GO:0046546 88 0.068
Mouse
regulation of histone methylation GO:0031060 30 0.067
regulation of mrna stability GO:0043488 23 0.065
oogenesis GO:0048477 56 0.065
signal transduction by p53 class mediator GO:0072331 51 0.063
negative regulation of mrna processing GO:0050686 12 0.060
regulation of mrna splicing via spliceosome GO:0048024 32 0.060
regulation of cellular component biogenesis GO:0044087 181 0.060
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.060
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.060
purine nucleoside metabolic process GO:0042278 241 0.060
response to extracellular stimulus GO:0009991 127 0.058
regulation of chromatin modification GO:1903308 57 0.057
ossification GO:0001503 216 0.057
heterochromatin assembly GO:0031507 2 0.056
i kappab kinase nf kappab signaling GO:0007249 85 0.056
mrna catabolic process GO:0006402 22 0.055
ras protein signal transduction GO:0007265 77 0.055
positive regulation of mrna metabolic process GO:1903313 17 0.055
respiratory tube development GO:0030323 167 0.055
cellular macromolecule catabolic process GO:0044265 206 0.055
regulation of cell cycle phase transition GO:1901987 77 0.054
negative regulation of cell cycle process GO:0010948 69 0.054
mitotic cell cycle GO:0000278 195 0.054
sensory perception GO:0007600 245 0.053
aromatic compound catabolic process GO:0019439 286 0.052
cellular nitrogen compound catabolic process GO:0044270 280 0.052
translation GO:0006412 93 0.051
chromatin remodeling GO:0006338 32 0.051
negative regulation of gene expression epigenetic GO:0045814 15 0.050
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.050
posttranscriptional regulation of gene expression GO:0010608 155 0.050
response to molecule of bacterial origin GO:0002237 143 0.049
positive regulation of histone h3 k9 methylation GO:0051574 4 0.049
response to hypoxia GO:0001666 58 0.049
nucleocytoplasmic transport GO:0006913 139 0.049
adult locomotory behavior GO:0008344 91 0.047
rna splicing GO:0008380 54 0.047
positive regulation of apoptotic process GO:0043065 217 0.047
nuclear division GO:0000280 158 0.047
regulation of generation of precursor metabolites and energy GO:0043467 38 0.046
positive regulation of cell death GO:0010942 224 0.046
cellular lipid metabolic process GO:0044255 323 0.046
hematopoietic progenitor cell differentiation GO:0002244 143 0.045
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.045
rna stabilization GO:0043489 9 0.044
negative regulation of mrna splicing via spliceosome GO:0048025 12 0.044
regulation of mrna metabolic process GO:1903311 43 0.044
purine nucleoside triphosphate metabolic process GO:0009144 226 0.044
regulation of rna stability GO:0043487 26 0.043
forebrain development GO:0030900 302 0.043
response to heat GO:0009408 27 0.042
posttranscriptional gene silencing GO:0016441 10 0.042
b cell differentiation GO:0030183 78 0.042
Mouse
base excision repair GO:0006284 9 0.042
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.042
rna transport GO:0050658 18 0.041
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.041
modification dependent macromolecule catabolic process GO:0043632 133 0.041
dna biosynthetic process GO:0071897 22 0.041
regulation of membrane potential GO:0042391 192 0.041
rna dependent dna replication GO:0006278 3 0.040
ribonucleoside metabolic process GO:0009119 245 0.040
ventricular system development GO:0021591 27 0.040
dna integrity checkpoint GO:0031570 28 0.040
locomotory behavior GO:0007626 195 0.040
regulation of transcription by chromatin organization GO:0034401 0 0.040
regulation of apoptotic signaling pathway GO:2001233 197 0.039
Mouse
histone exchange GO:0043486 8 0.039
insemination GO:0007320 6 0.039
macromolecule deacylation GO:0098732 37 0.039
female gonad development GO:0008585 71 0.038
double strand break repair GO:0006302 48 0.038
methylation GO:0032259 134 0.038
nucleobase containing small molecule metabolic process GO:0055086 352 0.037
cell cycle g1 s phase transition GO:0044843 57 0.037
regulation of peptidase activity GO:0052547 96 0.037
viral process GO:0016032 41 0.037
regulation of cellular catabolic process GO:0031329 242 0.036
circulatory system process GO:0003013 197 0.036
negative regulation of translation GO:0017148 22 0.036
carbohydrate catabolic process GO:0016052 32 0.036
maternal placenta development GO:0001893 20 0.036
negative regulation of mitotic cell cycle GO:0045930 58 0.035
negative regulation of b cell activation GO:0050869 27 0.035
Mouse
protein maturation GO:0051604 176 0.035
negative regulation of phosphate metabolic process GO:0045936 184 0.035
mrna processing GO:0006397 63 0.035
microtubule cytoskeleton organization GO:0000226 157 0.034
regulation of mitosis GO:0007088 29 0.034
skeletal system development GO:0001501 356 0.034
response to glucocorticoid GO:0051384 20 0.034
positive regulation of nervous system development GO:0051962 221 0.034
rna catabolic process GO:0006401 29 0.034
leukocyte differentiation GO:0002521 342 0.033
Mouse
epithelial cell proliferation GO:0050673 174 0.033
maternal process involved in female pregnancy GO:0060135 32 0.033
positive regulation of dna templated transcription elongation GO:0032786 2 0.033
nucleoside metabolic process GO:0009116 246 0.033
lateral inhibition GO:0046331 1 0.033
ribonucleoside monophosphate metabolic process GO:0009161 80 0.033
regulation of b cell differentiation GO:0045577 23 0.032
Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.032
protein modification by small protein conjugation or removal GO:0070647 207 0.032
epidermal cell division GO:0010481 3 0.032
organ regeneration GO:0031100 2 0.032
nuclear export GO:0051168 34 0.031
regulation of response to dna damage stimulus GO:2001020 34 0.031
nuclear transport GO:0051169 139 0.031
positive regulation of protein modification process GO:0031401 299 0.031
regulation of translation GO:0006417 71 0.031
response to decreased oxygen levels GO:0036293 59 0.030
rna splicing via transesterification reactions GO:0000375 43 0.030
regulation of cell division GO:0051302 76 0.030
cellular response to organic cyclic compound GO:0071407 87 0.030
oocyte development GO:0048599 33 0.029
histone h4 k20 methylation GO:0034770 8 0.029
purine ribonucleoside metabolic process GO:0046128 241 0.029
negative regulation of dna templated transcription termination GO:0060567 1 0.029
multi multicellular organism process GO:0044706 109 0.029
purine nucleotide metabolic process GO:0006163 302 0.029
protein deacetylation GO:0006476 32 0.029
dna conformation change GO:0071103 37 0.028
regulation of circadian rhythm GO:0042752 58 0.028
inflammatory response GO:0006954 244 0.028
cytoplasmic transport GO:0016482 234 0.028
macromolecule methylation GO:0043414 120 0.028
negative regulation of protein modification process GO:0031400 163 0.028
receptor biosynthetic process GO:0032800 3 0.028
negative regulation of intracellular signal transduction GO:1902532 167 0.028
negative regulation of wnt signaling pathway GO:0030178 73 0.028
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.028
positive regulation of programmed cell death GO:0043068 218 0.028
cellular biogenic amine metabolic process GO:0006576 28 0.028
positive regulation of glycogen metabolic process GO:0070875 8 0.027
g1 s transition of mitotic cell cycle GO:0000082 57 0.027
histone deacetylation GO:0016575 26 0.027
regulation of polysaccharide metabolic process GO:0032881 13 0.026
regulation of endocytosis GO:0030100 69 0.026
dna dependent dna replication GO:0006261 24 0.026
positive regulation of cellular amine metabolic process GO:0033240 5 0.026
b cell activation GO:0042113 161 0.026
Mouse
nucleus organization GO:0006997 45 0.026
Mouse
establishment of organelle localization GO:0051656 122 0.026
regulation of cytoplasmic transport GO:1903649 112 0.026
cellular protein catabolic process GO:0044257 155 0.026
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.025
positive regulation of neuron differentiation GO:0045666 141 0.025
visual learning GO:0008542 44 0.025
embryonic organ morphogenesis GO:0048562 276 0.024
male sex differentiation GO:0046661 109 0.024
Mouse
compound eye development GO:0048749 1 0.024
termination of rna polymerase ii transcription GO:0006369 1 0.024
anatomical structure homeostasis GO:0060249 145 0.024
poly a mrna export from nucleus GO:0016973 4 0.024
striated muscle cell development GO:0055002 125 0.023
negative regulation of neuron apoptotic process GO:0043524 92 0.023
chromatin silencing at rdna GO:0000183 3 0.023
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.023
amp metabolic process GO:0046033 4 0.023
regulation of protein localization GO:0032880 231 0.023
ribonucleoside biosynthetic process GO:0042455 21 0.023
neuron death GO:0070997 154 0.023
adult behavior GO:0030534 135 0.022
limb development GO:0060173 166 0.022
blood vessel morphogenesis GO:0048514 285 0.022
response to uv GO:0009411 44 0.022
positive regulation of mapk cascade GO:0043410 170 0.022
regulation of mitotic sister chromatid segregation GO:0033047 12 0.022
striated muscle tissue development GO:0014706 293 0.022
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.022
oocyte axis specification GO:0007309 2 0.022
positive regulation of dna binding GO:0043388 14 0.022
Mouse
telencephalon development GO:0021537 186 0.022
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.022
pallium development GO:0021543 120 0.022
negative regulation of ras protein signal transduction GO:0046580 18 0.022
oocyte anterior posterior axis specification GO:0007314 2 0.022
microtubule based process GO:0007017 236 0.022
development of primary female sexual characteristics GO:0046545 73 0.022
cell junction assembly GO:0034329 52 0.021
histone methylation GO:0016571 71 0.021
muscle cell differentiation GO:0042692 261 0.021
peptidyl amino acid modification GO:0018193 336 0.021
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.021
wnt signaling pathway GO:0016055 188 0.021
neural precursor cell proliferation GO:0061351 121 0.021
response to steroid hormone GO:0048545 56 0.021
mrna splice site selection GO:0006376 5 0.020
carbohydrate metabolic process GO:0005975 230 0.020
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.020
negative regulation of homeostatic process GO:0032845 71 0.020
response to denervation involved in regulation of muscle adaptation GO:0014894 4 0.020
response to oxygen levels GO:0070482 62 0.020
dna packaging GO:0006323 30 0.019
purine nucleoside monophosphate metabolic process GO:0009126 81 0.019
nuclear import GO:0051170 95 0.019
rna processing GO:0006396 105 0.019
atp catabolic process GO:0006200 55 0.019
regulation of ras protein signal transduction GO:0046578 114 0.019
hippocampus development GO:0021766 52 0.019
epithelial cell development GO:0002064 159 0.019
blood circulation GO:0008015 195 0.019
protein processing GO:0016485 163 0.019
regulation of mrna processing GO:0050684 41 0.019
positive regulation of mitotic cell cycle GO:0045931 41 0.019
meiotic chromosome segregation GO:0045132 19 0.019
carbohydrate derivative biosynthetic process GO:1901137 183 0.019
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.019
regulation of cell activation GO:0050865 289 0.019
Mouse
maternal determination of anterior posterior axis embryo GO:0008358 2 0.019
macromolecule catabolic process GO:0009057 281 0.019
regulation of leukocyte differentiation GO:1902105 159 0.018
Mouse
cell type specific apoptotic process GO:0097285 268 0.018
positive regulation of mrna splicing via spliceosome GO:0048026 11 0.018
covalent chromatin modification GO:0016569 163 0.018
mesenchyme development GO:0060485 152 0.018
regulation of chromatin organization GO:1902275 57 0.018
atp metabolic process GO:0046034 75 0.018
nuclear mrna surveillance GO:0071028 1 0.018
regulation of histone modification GO:0031056 56 0.018
endocytosis GO:0006897 168 0.018
regulation of system process GO:0044057 200 0.018
negative regulation of neuron projection regeneration GO:0070571 3 0.018
ear development GO:0043583 200 0.018
regulation of dna binding GO:0051101 39 0.018
Mouse
maintenance of location GO:0051235 89 0.018
intracellular protein transport GO:0006886 204 0.018
membrane depolarization GO:0051899 64 0.017
developmental maturation GO:0021700 193 0.017
homeostasis of number of cells GO:0048872 210 0.017
cellular chemical homeostasis GO:0055082 215 0.017
protein alkylation GO:0008213 81 0.017
negative regulation of chromatin silencing GO:0031936 1 0.017
regulation of dna templated transcription termination GO:0031554 1 0.017
heterochromatin organization GO:0070828 4 0.017
regulation of epithelial cell proliferation GO:0050678 141 0.017
regulation of protein localization to nucleus GO:1900180 60 0.017
purine ribonucleotide catabolic process GO:0009154 208 0.017
chemotaxis GO:0006935 247 0.017
dna replication independent nucleosome assembly GO:0006336 1 0.017
cellular response to oxidative stress GO:0034599 76 0.017
fungiform papilla morphogenesis GO:0061197 5 0.017
regulation of hydrolase activity GO:0051336 246 0.017
dna hypermethylation GO:0044026 3 0.017
nucleoside monophosphate catabolic process GO:0009125 59 0.016
rhythmic process GO:0048511 174 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.016
positive regulation of translation GO:0045727 19 0.016
mitotic cytokinesis GO:0000281 4 0.016
cellular homeostasis GO:0019725 240 0.016
histone h4 k20 trimethylation GO:0034773 2 0.016
positive regulation of apoptotic signaling pathway GO:2001235 95 0.016
purine nucleoside triphosphate catabolic process GO:0009146 203 0.016
regulation of multi organism process GO:0043900 111 0.016
negative regulation of necrotic cell death GO:0060547 11 0.016
purine containing compound metabolic process GO:0072521 311 0.016
organophosphate catabolic process GO:0046434 232 0.016
protein oligomerization GO:0051259 67 0.016
execution phase of apoptosis GO:0097194 19 0.016
regulation of protein catabolic process GO:0042176 108 0.016
female sex differentiation GO:0046660 84 0.016
regulation of neuron apoptotic process GO:0043523 122 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.016
negative regulation of cell cycle phase transition GO:1901988 48 0.016
cellular carbohydrate catabolic process GO:0044275 15 0.016
connective tissue development GO:0061448 179 0.016
mrna metabolic process GO:0016071 84 0.016
negative regulation of apoptotic signaling pathway GO:2001234 104 0.016
Mouse
intracellular mrna localization GO:0008298 4 0.016
germ line stem cell maintenance GO:0030718 6 0.016
regulation of mapk cascade GO:0043408 248 0.016
phagocytosis GO:0006909 66 0.016
germ cell proliferation GO:0036093 7 0.015
oocyte construction GO:0007308 2 0.015
positive regulation of binding GO:0051099 49 0.015
Mouse
regulation of response to wounding GO:1903034 189 0.015
blastocyst development GO:0001824 80 0.015
negative regulation of cell proliferation GO:0008285 296 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.015
negative regulation of endocytosis GO:0045806 12 0.015
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 19 0.015
sensory perception of pain GO:0019233 47 0.015
cellular response to lipid GO:0071396 145 0.015
ribonucleoside monophosphate catabolic process GO:0009158 57 0.015
purine nucleoside catabolic process GO:0006152 205 0.015
respiratory gaseous exchange GO:0007585 43 0.015
determination of left right symmetry GO:0007368 80 0.015
atp dependent chromatin remodeling GO:0043044 9 0.015
axonogenesis GO:0007409 274 0.015
histone h3 k9 dimethylation GO:0036123 4 0.015
myeloid cell homeostasis GO:0002262 114 0.015
negative regulation of leukocyte differentiation GO:1902106 51 0.015
Mouse
establishment of rna localization GO:0051236 18 0.015
cell fate specification GO:0001708 72 0.015
limbic system development GO:0021761 72 0.015
cell chemotaxis GO:0060326 81 0.015
ribonucleotide metabolic process GO:0009259 291 0.014
nucleoside phosphate metabolic process GO:0006753 338 0.014
fatty acid biosynthetic process GO:0006633 41 0.014
learning or memory GO:0007611 148 0.014
organic cyclic compound catabolic process GO:1901361 295 0.014
learning GO:0007612 98 0.014
negative regulation of protein complex disassembly GO:0043242 22 0.014
positive regulation of peptidase activity GO:0010952 49 0.014
regulation of microtubule polymerization or depolymerization GO:0031110 20 0.014
regulation of binding GO:0051098 111 0.014
Mouse
chromatin assembly or disassembly GO:0006333 16 0.014
muscle cell development GO:0055001 133 0.014
skin development GO:0043588 220 0.014
regulation of protein complex disassembly GO:0043244 28 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
embryonic limb morphogenesis GO:0030326 126 0.014
purine nucleoside biosynthetic process GO:0042451 19 0.014
genitalia development GO:0048806 37 0.014
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.014
negative regulation of neuron death GO:1901215 98 0.014
mrna splicing via spliceosome GO:0000398 43 0.014
regulation of neuron death GO:1901214 134 0.014
notch signaling pathway GO:0007219 71 0.014
cartilage development GO:0051216 140 0.014
palate development GO:0060021 76 0.014
positive regulation of endopeptidase activity GO:0010950 43 0.013
placenta development GO:0001890 140 0.013
negative regulation of nucleotide metabolic process GO:0045980 16 0.013
regulation of cellular response to stress GO:0080135 159 0.013
positive regulation of growth GO:0045927 104 0.013
membrane organization GO:0061024 245 0.013
ribonucleotide catabolic process GO:0009261 208 0.013
positive regulation of cell development GO:0010720 237 0.013
regulation of sister chromatid segregation GO:0033045 13 0.013
meiosis i GO:0007127 60 0.013
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.013
cardiolipin metabolic process GO:0032048 3 0.013
regulation of erk1 and erk2 cascade GO:0070372 71 0.013
sperm individualization GO:0007291 1 0.013
oocyte differentiation GO:0009994 35 0.013
amp biosynthetic process GO:0006167 2 0.013
response to organic cyclic compound GO:0014070 198 0.013
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.013
gene silencing by mirna GO:0035195 10 0.013
negative regulation of cellular catabolic process GO:0031330 47 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.013
Mouse
nucleobase containing compound transport GO:0015931 27 0.013
nucleoside phosphate biosynthetic process GO:1901293 79 0.013
protein deacylation GO:0035601 36 0.013
cardiac muscle cell differentiation GO:0055007 69 0.013
dna damage response signal transduction by p53 class mediator GO:0030330 19 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.013
cellular response to external stimulus GO:0071496 88 0.013
positive regulation of cell cycle process GO:0090068 61 0.013
cell maturation GO:0048469 127 0.013
regulation of double strand break repair via nonhomologous end joining GO:2001032 2 0.013
cellular carbohydrate metabolic process GO:0044262 119 0.013
circadian regulation of gene expression GO:0032922 48 0.012
cellular ion homeostasis GO:0006873 165 0.012
cellular protein complex assembly GO:0043623 116 0.012
purine containing compound catabolic process GO:0072523 213 0.012
protein ubiquitination GO:0016567 171 0.012
ribose phosphate metabolic process GO:0019693 291 0.012
nucleoside catabolic process GO:0009164 206 0.012
regulation of neural precursor cell proliferation GO:2000177 70 0.012
negative regulation of transferase activity GO:0051348 85 0.012
regulation of cellular carbohydrate catabolic process GO:0043471 12 0.012
negative regulation of neuron differentiation GO:0045665 101 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
regulation of kinase activity GO:0043549 249 0.012
neuron maturation GO:0042551 29 0.012
negative regulation of dna replication GO:0008156 4 0.012
replication fork processing GO:0031297 1 0.012

Hmgb1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.034
disease of anatomical entity DOID:7 0 0.034
neurodegenerative disease DOID:1289 0 0.034
nervous system disease DOID:863 0 0.034
muscular disease DOID:0080000 0 0.028
musculoskeletal system disease DOID:17 0 0.028
muscle tissue disease DOID:66 0 0.028
disease of mental health DOID:150 0 0.022
myopathy DOID:423 0 0.016