|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.920
|
Mouse |
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.880
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.795
|
Mouse |
|
|
response to growth factor
|
GO:0070848 |
198 |
0.681
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.667
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.652
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.629
|
Mouse |
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.532
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.529
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.527
|
Mouse |
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.527
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.520
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.505
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.492
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.473
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.470
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.466
|
Mouse |
|
|
response to interleukin 12
|
GO:0070671 |
2 |
0.460
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.457
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.456
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.442
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.441
|
Mouse |
|
|
mapk cascade
|
GO:0000165 |
281 |
0.417
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.406
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.406
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.402
|
Mouse |
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.369
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.365
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.359
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.358
|
|
|
|
regulation of interferon beta biosynthetic process
|
GO:0045357 |
4 |
0.357
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.345
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.337
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.327
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.319
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.315
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.314
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.313
|
Mouse |
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.312
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.307
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.306
|
Mouse |
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.306
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.299
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.289
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.287
|
|
|
|
positive regulation of response to cytokine stimulus
|
GO:0060760 |
11 |
0.286
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.282
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.278
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.274
|
Mouse |
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.269
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.267
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.264
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.261
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.260
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.257
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.257
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.256
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.250
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.250
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.249
|
|
|
|
interferon beta biosynthetic process
|
GO:0045350 |
4 |
0.249
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.248
|
Mouse |
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.248
|
Mouse |
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.247
|
|
|
|
response to dsrna
|
GO:0043331 |
30 |
0.245
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.241
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.240
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.238
|
Mouse |
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.236
|
Mouse |
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.233
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.230
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.229
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.228
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.222
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.221
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.218
|
Mouse |
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.216
|
Mouse |
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.215
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.213
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.211
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.208
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.207
|
Mouse |
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.206
|
|
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.206
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.205
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.204
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.201
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.196
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.195
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.191
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
31 |
0.191
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.188
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.187
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.184
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.184
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.182
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.178
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.174
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.170
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.169
|
|
|
|
protein alkylation
|
GO:0008213 |
81 |
0.169
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.169
|
|
|
|
negative regulation of toll like receptor signaling pathway
|
GO:0034122 |
14 |
0.166
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.163
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.163
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.162
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.161
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.161
|
Mouse |
|
|
myd88 independent toll like receptor signaling pathway
|
GO:0002756 |
3 |
0.157
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.157
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.152
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.151
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.151
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.150
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.150
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.149
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.147
|
Mouse |
|
|
chemotaxis
|
GO:0006935 |
247 |
0.146
|
|
|
|
regulation of macrophage differentiation
|
GO:0045649 |
9 |
0.143
|
|
|
|
regulation of chemokine production
|
GO:0032642 |
30 |
0.143
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.142
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.140
|
Mouse |
|
|
immune effector process
|
GO:0002252 |
321 |
0.139
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.137
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.135
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.135
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.135
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.134
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.133
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.132
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.131
|
Mouse |
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.130
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.127
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.123
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.123
|
|
|
|
positive regulation of interleukin 6 production
|
GO:0032755 |
37 |
0.122
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.122
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.122
|
|
|
|
regulation of interleukin 12 production
|
GO:0032655 |
30 |
0.119
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.119
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.118
|
Mouse |
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.117
|
Mouse |
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.114
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.114
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.113
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.111
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.111
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.108
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.107
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.107
|
|
|
|
mast cell proliferation
|
GO:0070662 |
4 |
0.107
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.106
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.105
|
|
|
|
response to interleukin 15
|
GO:0070672 |
3 |
0.105
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.104
|
|
|
|
positive regulation of interleukin 8 production
|
GO:0032757 |
2 |
0.102
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.102
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.101
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.101
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.101
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.101
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.100
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.100
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.099
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.098
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.097
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.095
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.094
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.094
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.093
|
Mouse |
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.093
|
Mouse |
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
4 |
0.093
|
|
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.092
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.092
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.091
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.091
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.089
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.089
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.089
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.089
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.089
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.088
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.087
|
|
|
|
interleukin 1 production
|
GO:0032612 |
31 |
0.086
|
|
|
|
regulation of natural killer cell activation
|
GO:0032814 |
22 |
0.086
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.086
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.085
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.085
|
|
|
|
regulation of mast cell proliferation
|
GO:0070666 |
4 |
0.085
|
|
|
|
positive regulation of interferon beta production
|
GO:0032728 |
8 |
0.084
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.084
|
|
|
|
positive regulation of type i interferon production
|
GO:0032481 |
14 |
0.084
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.083
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.083
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.081
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.080
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.080
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.079
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.079
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.078
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.077
|
|
|
|
chemokine production
|
GO:0032602 |
34 |
0.077
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.076
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.076
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.076
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.076
|
|
|
|
regulation of toll like receptor 2 signaling pathway
|
GO:0034135 |
3 |
0.075
|
|
|
|
positive regulation of chemokine production
|
GO:0032722 |
22 |
0.075
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.073
|
Mouse |
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.073
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.073
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.072
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.071
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.071
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.071
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.071
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.071
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.071
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.071
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
3 |
0.070
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.069
|
|
|
|
t cell selection
|
GO:0045058 |
34 |
0.069
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.069
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.068
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.068
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.068
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.068
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.067
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.067
|
|
|
|
type i interferon signaling pathway
|
GO:0060337 |
10 |
0.066
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
39 |
0.066
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.065
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.065
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.064
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
26 |
0.064
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.064
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.064
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.064
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.064
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.064
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.063
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.062
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.062
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.062
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.062
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.061
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.060
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.060
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.060
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.060
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.060
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.060
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.059
|
|
|
|
growth of symbiont involved in interaction with host
|
GO:0044116 |
23 |
0.059
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.059
|
|
|
|
cellular response to type i interferon
|
GO:0071357 |
10 |
0.059
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.058
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.058
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.058
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.057
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.057
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.057
|
|
|
|
macrophage differentiation
|
GO:0030225 |
20 |
0.057
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.057
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.056
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.056
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.056
|
|
|
|
interferon beta production
|
GO:0032608 |
16 |
0.055
|
|
|
|
positive regulation of binding
|
GO:0051099 |
49 |
0.055
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.055
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.054
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.054
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.054
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.054
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.053
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.052
|
|
|
|
regulation of toll like receptor 4 signaling pathway
|
GO:0034143 |
4 |
0.052
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.052
|
|
|
|
response to type i interferon
|
GO:0034340 |
12 |
0.052
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.052
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.052
|
|
|
|
regulation of toll like receptor signaling pathway
|
GO:0034121 |
20 |
0.052
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.051
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.051
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.051
|
Mouse |
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.051
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.051
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.050
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.050
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.050
|
|
|
|
t cell homeostasis
|
GO:0043029 |
35 |
0.050
|
|
|
|
regulation of t cell mediated immunity
|
GO:0002709 |
34 |
0.050
|
Mouse |
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.050
|
Mouse |
|
|
positive regulation of interferon alpha production
|
GO:0032727 |
4 |
0.049
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.049
|
|
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
41 |
0.049
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.049
|
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.048
|
Mouse |
|
|
positive regulation of tumor necrosis factor production
|
GO:0032760 |
30 |
0.048
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.048
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.048
|
Mouse |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.047
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.047
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.047
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.046
|
|
|
|
regulation of coagulation
|
GO:0050818 |
31 |
0.046
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.046
|
|
|
|
hepatocyte growth factor receptor signaling pathway
|
GO:0048012 |
3 |
0.046
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.046
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.045
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.045
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.045
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.045
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.044
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.044
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.044
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.044
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.044
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.044
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.044
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.044
|
|
|
|
dendritic cell apoptotic process
|
GO:0097048 |
3 |
0.044
|
|
|
|
immune response inhibiting signal transduction
|
GO:0002765 |
4 |
0.044
|
Mouse |
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.043
|
|
|
|
nucleotide binding oligomerization domain containing signaling pathway
|
GO:0070423 |
6 |
0.043
|
|
|
|
protein methylation
|
GO:0006479 |
81 |
0.043
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.043
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.043
|
|
|
|
natural killer cell activation
|
GO:0030101 |
44 |
0.043
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
13 |
0.043
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.043
|
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.043
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.042
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.042
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.042
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.042
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.042
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.041
|
Mouse |
|
|
blood circulation
|
GO:0008015 |
195 |
0.041
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.040
|
|
|
|
regulation of dendritic cell apoptotic process
|
GO:2000668 |
3 |
0.040
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.039
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.039
|
Mouse |
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.039
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.039
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.039
|
|
|
|
interleukin 8 production
|
GO:0032637 |
4 |
0.039
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.039
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.039
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.039
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.039
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.039
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.039
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.039
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.039
|
|
|
|
type i interferon biosynthetic process
|
GO:0045351 |
9 |
0.039
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
53 |
0.038
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.038
|
|
|
|
response to retinoic acid
|
GO:0032526 |
56 |
0.038
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.038
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.038
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.038
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.038
|
|
|
|
jak stat cascade
|
GO:0007259 |
42 |
0.037
|
|
|
|
neural tube closure
|
GO:0001843 |
90 |
0.037
|
|
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
9 |
0.037
|
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.037
|
|
|
|
regulation of humoral immune response
|
GO:0002920 |
22 |
0.037
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.037
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.037
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.037
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.037
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.037
|
|
|
|
regulation of cd8 positive alpha beta cytotoxic t cell extravasation
|
GO:2000452 |
2 |
0.037
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.036
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.036
|
Mouse |
|
|
positive regulation of dendritic cell apoptotic process
|
GO:2000670 |
3 |
0.036
|
|
|
|
peptidyl lysine methylation
|
GO:0018022 |
29 |
0.036
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.036
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
34 |
0.036
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
28 |
0.036
|
Mouse |
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.036
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.036
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.036
|
|
|
|
vacuole organization
|
GO:0007033 |
38 |
0.035
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.035
|
|
|
|
positive regulation of type i interferon mediated signaling pathway
|
GO:0060340 |
4 |
0.035
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.035
|
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.035
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.035
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.034
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.034
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.034
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.034
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.034
|
|
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
62 |
0.034
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.034
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.034
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.034
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.034
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.033
|
|
|
|
positive regulation of protein binding
|
GO:0032092 |
29 |
0.033
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.033
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.033
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.033
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.033
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.033
|
|
|
|
positive regulation of podosome assembly
|
GO:0071803 |
3 |
0.033
|
|
|
|
interleukin 1 beta secretion
|
GO:0050702 |
16 |
0.033
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.033
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.033
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.033
|
|
|
|
cellular response to interleukin 15
|
GO:0071350 |
2 |
0.032
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.032
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.032
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.032
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.032
|
|
|
|
cellular response to peptidoglycan
|
GO:0071224 |
4 |
0.032
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.031
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.031
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.031
|
|
|
|
histamine transport
|
GO:0051608 |
2 |
0.031
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.031
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.031
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.031
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.031
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.031
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.031
|
|
|
|
regulation of activated t cell proliferation
|
GO:0046006 |
16 |
0.031
|
|
|
|
growth involved in symbiotic interaction
|
GO:0044110 |
23 |
0.030
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.030
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.030
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.030
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.030
|
|
|
|
development of secondary male sexual characteristics
|
GO:0046544 |
3 |
0.030
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.030
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.030
|
|
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.030
|
|
|
|
positive regulation of chemokine biosynthetic process
|
GO:0045080 |
6 |
0.030
|
|
|
|
type i interferon production
|
GO:0032606 |
29 |
0.030
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.030
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.030
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.029
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.029
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.029
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.029
|
|
|
|
positive regulation of gamma delta t cell differentiation
|
GO:0045588 |
6 |
0.029
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.029
|
Mouse |
|
|
negative regulation of alcohol biosynthetic process
|
GO:1902931 |
4 |
0.029
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.029
|
|
|
|
zymogen activation
|
GO:0031638 |
41 |
0.029
|
|
|
|
regulation of cell killing
|
GO:0031341 |
40 |
0.029
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.029
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.029
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.029
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.029
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.029
|
Mouse |
|
|
chromatin modification
|
GO:0016568 |
187 |
0.029
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.028
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
30 |
0.028
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.028
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.028
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.028
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.028
|
|
|
|
regulation of t cell extravasation
|
GO:2000407 |
3 |
0.028
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.028
|
|
|
|
regulation of mast cell differentiation
|
GO:0060375 |
3 |
0.028
|
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
23 |
0.028
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.028
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
34 |
0.028
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.028
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.028
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.028
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.028
|
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.028
|
|
|
|
lactation
|
GO:0007595 |
25 |
0.028
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.028
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.027
|
|
|
|
interleukin 2 mediated signaling pathway
|
GO:0038110 |
2 |
0.027
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.027
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.027
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.027
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.027
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.027
|
|
|
|
necrotic cell death
|
GO:0070265 |
30 |
0.027
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.027
|
|
|
|
negative regulation of erk1 and erk2 cascade
|
GO:0070373 |
21 |
0.027
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.027
|
|
|
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.027
|
|
|
|
negative regulation of growth of symbiont involved in interaction with host
|
GO:0044146 |
19 |
0.026
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.026
|
|
