IMP

Process View

Mus musculus

9 genes annotated in mouse

Multi-species View

regulation of macrophage differentiation

GO:0045649

Any process that modulates the frequency, rate or extent of macrophage differentiation.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of macrophage differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of macrophage differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
Id3	inhibitor of DNA binding 3	0.859	Mouse
Id1	inhibitor of DNA binding 1	0.563	Mouse
Gata4	GATA binding protein 4	0.454	Mouse
Stat3	signal transducer and activator of transcription 3	0.446
Fas	Fas (TNF receptor superfamily member 6)	0.389
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.337
Pten	phosphatase and tensin homolog	0.335
Ldb3	LIM domain binding 3	0.323
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.283
Fgd1	FYVE, RhoGEF and PH domain containing 1	0.277
Ctnnb1	catenin (cadherin associated protein), beta 1	0.273
C1qa	complement component 1, q subcomponent, alpha polypeptide	0.255
Jag1	jagged 1	0.192
C1qb	complement component 1, q subcomponent, beta polypeptide	0.191
Ifnar1	interferon (alpha and beta) receptor 1	0.143
Tyrobp	TYRO protein tyrosine kinase binding protein	0.133
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.132
Notch1	Notch gene homolog 1 (Drosophila)	0.130
Src	Rous sarcoma oncogene	0.110
Csf1r	colony stimulating factor 1 receptor	0.110
Igh	immunoglobulin heavy chain complex	0.101
Gata6	GATA binding protein 6	0.093	Mouse
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.092
Fadd	Fas (TNFRSF6)-associated via death domain	0.086	Human
Nf1	neurofibromatosis 1	0.085
Trp53	transformation related protein 53	0.082
Kit	kit oncogene	0.080
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.080
Ikzf1	IKAROS family zinc finger 1	0.078
Casp8	caspase 8	0.069	Human
Smad6	MAD homolog 6 (Drosophila)	0.067
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.066
Rb1	retinoblastoma 1	0.065
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.063
Tcf3	transcription factor 3	0.062
Zfpm2	zinc finger protein, multitype 2	0.058
Apaf1	apoptotic peptidase activating factor 1	0.057
Lyz2	lysozyme 2	0.055
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.055
Hes1	hairy and enhancer of split 1 (Drosophila)	0.055
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.054
Sox4	SRY-box containing gene 4	0.052
Tcf4	transcription factor 4	0.050
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.048
Kitl	kit ligand	0.047
Alox5ap	arachidonate 5-lipoxygenase activating protein	0.047
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.043
Fgfr2	fibroblast growth factor receptor 2	0.042
Dll1	delta-like 1 (Drosophila)	0.041
Tal1	T-cell acute lymphocytic leukemia 1	0.038
Ripk3	receptor-interacting serine-threonine kinase 3	0.036
Tcirg1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3	0.033
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.033
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.033
Nos3	nitric oxide synthase 3, endothelial cell	0.032
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.030
Itgb2	integrin beta 2	0.030
Rxra	retinoid X receptor alpha	0.028
Col1a1	collagen, type I, alpha 1	0.028
Ifngr1	interferon gamma receptor 1	0.027
Pkdcc	protein kinase domain containing, cytoplasmic	0.025
Tbx3	T-box 3	0.025
Hs1bp3	HCLS1 binding protein 3	0.024
Myo6	myosin VI	0.024
Nsf	N-ethylmaleimide sensitive fusion protein	0.024
Gja1	gap junction protein, alpha 1	0.024
Traf6	TNF receptor-associated factor 6	0.024
Lef1	lymphoid enhancer binding factor 1	0.023
Fyb	FYN binding protein	0.022
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.022
Cyld	cylindromatosis (turban tumor syndrome)	0.022
Actn2	actinin alpha 2	0.021
Il6st	interleukin 6 signal transducer	0.020
Plcd1	phospholipase C, delta 1	0.020
Fgfr3	fibroblast growth factor receptor 3	0.019
Stat6	signal transducer and activator of transcription 6	0.019
Ncoa1	nuclear receptor coactivator 1	0.019
Pparg	peroxisome proliferator activated receptor gamma	0.019
Shank3	SH3/ankyrin domain gene 3	0.018
Gli3	GLI-Kruppel family member GLI3	0.018
Cfp	complement factor properdin	0.018
Psen1	presenilin 1	0.017
Prkce	protein kinase C, epsilon	0.017	Mouse
Ly86	lymphocyte antigen 86	0.017
C3	complement component 3	0.017
Tgfb2	transforming growth factor, beta 2	0.017
H2-Aa	histocompatibility 2, class II antigen A, alpha	0.017
Emx1	empty spiracles homolog 1 (Drosophila)	0.016
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.015
Bmp4	bone morphogenetic protein 4	0.015
Ctss	cathepsin S	0.015
Runx1	runt related transcription factor 1	0.015
Hhex	hematopoietically expressed homeobox	0.015
Sgpl1	sphingosine phosphate lyase 1	0.014
Klf3	Kruppel-like factor 3 (basic)	0.014
Pitx2	paired-like homeodomain transcription factor 2	0.014
Smad4	MAD homolog 4 (Drosophila)	0.014
Rbl1	retinoblastoma-like 1 (p107)	0.014	Mouse
Yap1	yes-associated protein 1	0.013
Myd88	myeloid differentiation primary response gene 88	0.013
Pip4k2a	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	0.013
Ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.013
Casp3	caspase 3	0.013
Chuk	conserved helix-loop-helix ubiquitous kinase	0.013
Esr1	estrogen receptor 1 (alpha)	0.013
Ppp1ca	protein phosphatase 1, catalytic subunit, alpha isoform	0.013
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.013
Aif1	allograft inflammatory factor 1	0.013
Mrc1	mannose receptor, C type 1	0.013
Smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.013
Prkcc	protein kinase C, gamma	0.012
Efnb2	ephrin B2	0.012
Ccl6	chemokine (C-C motif) ligand 6	0.012
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.012
Snai1	snail homolog 1 (Drosophila)	0.012
Tbx5	T-box 5	0.012
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.012
Il1r1	interleukin 1 receptor, type I	0.012
Coro1a	coronin, actin binding protein 1A	0.012
Lmo2	LIM domain only 2	0.012
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.012
Bnc1	basonuclin 1	0.012
Clock	circadian locomotor output cycles kaput	0.012
Clec4n	C-type lectin domain family 4, member n	0.012
Lgals9	lectin, galactose binding, soluble 9	0.011
Kcnq1	potassium voltage-gated channel, subfamily Q, member 1	0.011
Igf1	insulin-like growth factor 1	0.011
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.011
Myc	myelocytomatosis oncogene	0.011
Sox11	SRY-box containing gene 11	0.011
Cd44	CD44 antigen	0.011
Cd68	CD68 antigen	0.011
Tgfb1	transforming growth factor, beta 1	0.011
Id2	inhibitor of DNA binding 2	0.011
Dlgap1	discs, large (Drosophila) homolog-associated protein 1	0.011
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.011
Prkcd	protein kinase C, delta	0.011
Chd7	chromodomain helicase DNA binding protein 7	0.011
Ptk2b	PTK2 protein tyrosine kinase 2 beta	0.010
Dlg3	discs, large homolog 3 (Drosophila)	0.010
Inpp5d	inositol polyphosphate-5-phosphatase D	0.010
Dlg1	discs, large homolog 1 (Drosophila)	0.010
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.010
Sox18	SRY-box containing gene 18	0.010
Ahr	aryl-hydrocarbon receptor	0.010