Mus musculus

106 known processes

Il2ra

interleukin 2 receptor, alpha chain

(Aliases: Ly-43,Il2r,MGC130561,CD25)

Il2ra biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of defense response GO:0031347 233 0.724
defense response to other organism GO:0098542 197 0.688
apoptotic signaling pathway GO:0097190 306 0.614
leukocyte proliferation GO:0070661 172 0.612
regulation of lymphocyte activation GO:0051249 240 0.600
regulation of cell activation GO:0050865 289 0.577
adaptive immune response GO:0002250 155 0.521
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.516
immune response activating signal transduction GO:0002757 116 0.510
positive regulation of lymphocyte proliferation GO:0050671 70 0.510
cytokine production GO:0001816 319 0.495
t cell activation GO:0042110 289 0.486
immune effector process GO:0002252 321 0.470
t cell proliferation GO:0042098 120 0.463
response to molecule of bacterial origin GO:0002237 143 0.446
cellular response to lipopolysaccharide GO:0071222 77 0.439
positive regulation of defense response GO:0031349 124 0.438
cellular response to cytokine stimulus GO:0071345 189 0.431
positive regulation of cell activation GO:0050867 158 0.430
leukocyte activation involved in immune response GO:0002366 126 0.428
lymphocyte proliferation GO:0046651 164 0.423
positive regulation of interferon gamma production GO:0032729 39 0.412
cytokine metabolic process GO:0042107 71 0.409
activation of immune response GO:0002253 138 0.375
leukocyte differentiation GO:0002521 342 0.372
cellular response to biotic stimulus GO:0071216 92 0.370
regulation of leukocyte mediated immunity GO:0002703 104 0.336
regulation of innate immune response GO:0045088 91 0.331
leukocyte mediated immunity GO:0002443 174 0.327
regulation of leukocyte proliferation GO:0070663 121 0.326
extrinsic apoptotic signaling pathway GO:0097191 126 0.318
regulation of cytokine production GO:0001817 266 0.302
response to lipopolysaccharide GO:0032496 128 0.300
regulation of t cell activation GO:0050863 170 0.299
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.294
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.289
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.288
positive regulation of t cell activation GO:0050870 101 0.287
cytokine mediated signaling pathway GO:0019221 115 0.281
cellular response to molecule of bacterial origin GO:0071219 83 0.268
positive regulation of cytokine production GO:0001819 174 0.266
cell activation involved in immune response GO:0002263 126 0.263
lymphocyte mediated immunity GO:0002449 139 0.260
positive regulation of leukocyte proliferation GO:0070665 73 0.250
interferon gamma production GO:0032609 67 0.239
positive regulation of t cell proliferation GO:0042102 52 0.238
cell killing GO:0001906 67 0.235
regulation of t cell proliferation GO:0042129 92 0.232
positive regulation of inflammatory response GO:0050729 47 0.232
interleukin 2 production GO:0032623 33 0.228
positive regulation of cell killing GO:0031343 33 0.228
cellular amino acid metabolic process GO:0006520 103 0.212
regulation of lymphocyte proliferation GO:0050670 117 0.212
regulation of interferon gamma production GO:0032649 57 0.207
lymphocyte differentiation GO:0030098 242 0.207
innate immune response GO:0045087 157 0.205
regulation of protein localization GO:0032880 231 0.197
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.194
natural killer cell activation GO:0030101 44 0.194
t cell differentiation GO:0030217 174 0.188
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.187
positive regulation of innate immune response GO:0045089 80 0.185
mature dendritic cell differentiation GO:0097029 3 0.184
positive regulation of immune effector process GO:0002699 107 0.181
leukocyte mediated cytotoxicity GO:0001909 62 0.180
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.176
positive regulation of lymphocyte activation GO:0051251 140 0.173
interleukin 12 secretion GO:0072610 3 0.172
inflammatory response GO:0006954 244 0.172
negative regulation of immune system process GO:0002683 209 0.171
myeloid cell differentiation GO:0030099 233 0.165
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.164
antigen receptor mediated signaling pathway GO:0050851 64 0.163
regulation of alpha beta t cell proliferation GO:0046640 18 0.162
immune response regulating signaling pathway GO:0002764 125 0.158
myeloid leukocyte activation GO:0002274 83 0.153
positive regulation of adaptive immune response GO:0002821 61 0.150
regulation of cell killing GO:0031341 40 0.148
cytokine biosynthetic process GO:0042089 68 0.146
alpha beta t cell proliferation GO:0046633 21 0.144
regulation of cytokine biosynthetic process GO:0042035 59 0.143
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.142
sequestering of calcium ion GO:0051208 18 0.135
chemotaxis GO:0006935 247 0.134
regulation of protein transport GO:0051223 163 0.125
positive regulation of natural killer cell mediated immunity GO:0002717 16 0.124
amine metabolic process GO:0009308 45 0.123
regulation of establishment of protein localization GO:0070201 181 0.120
sequestering of metal ion GO:0051238 19 0.119
negative regulation of protein metabolic process GO:0051248 282 0.118
myeloid leukocyte differentiation GO:0002573 119 0.116
membrane organization GO:0061024 245 0.116
regulation of apoptotic signaling pathway GO:2001233 197 0.115
regulation of vesicle mediated transport GO:0060627 139 0.113
t cell receptor signaling pathway GO:0050852 46 0.113
leukocyte apoptotic process GO:0071887 71 0.112
positive regulation of cytokine biosynthetic process GO:0042108 40 0.110
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.108
regulation of t cell extravasation GO:2000407 3 0.107
divalent inorganic cation homeostasis GO:0072507 138 0.106
positive regulation of leukocyte mediated immunity GO:0002705 70 0.101
positive regulation of t cell costimulation GO:2000525 2 0.101
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.100
regulation of alpha beta t cell activation GO:0046634 53 0.098
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.098
regulation of interleukin 4 biosynthetic process GO:0045402 3 0.096
cytokine secretion GO:0050663 72 0.096
signal transduction in absence of ligand GO:0038034 55 0.094
negative regulation of cytokine production GO:0001818 84 0.094
regulation of t cell costimulation GO:2000523 2 0.092
regulation of monocyte chemotaxis GO:0090025 3 0.089
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.089
regulation of dendritic cell chemotaxis GO:2000508 1 0.089
nucleoside phosphate metabolic process GO:0006753 338 0.088
cytoplasmic transport GO:0016482 234 0.088
inflammatory response to antigenic stimulus GO:0002437 30 0.087
t cell differentiation in thymus GO:0033077 77 0.087
cellular response to lipid GO:0071396 145 0.085
regulation of secretion GO:0051046 274 0.084
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.084
regulation of interleukin 2 production GO:0032663 28 0.084
cell chemotaxis GO:0060326 81 0.083
positive regulation of cellular amine metabolic process GO:0033240 5 0.082
positive regulation of monocyte extravasation GO:2000439 1 0.082
regulation of b cell proliferation GO:0030888 39 0.080
helper t cell chemotaxis GO:0035704 1 0.080
interleukin 2 biosynthetic process GO:0042094 15 0.080
purine nucleotide metabolic process GO:0006163 302 0.079
g protein coupled receptor signaling pathway GO:0007186 243 0.079
regulation of inflammatory response to antigenic stimulus GO:0002861 21 0.079
cellular ketone metabolic process GO:0042180 84 0.078
nucleotide metabolic process GO:0009117 332 0.077
defense response to bacterium GO:0042742 119 0.077
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.077
t cell extravasation GO:0072683 4 0.077
glycoprotein biosynthetic process GO:0009101 89 0.076
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.075
positive regulation of alpha beta t cell activation GO:0046635 39 0.075
cellular extravasation GO:0045123 17 0.074
regulation of leukocyte apoptotic process GO:2000106 56 0.074
regulation of chemotaxis GO:0050920 53 0.073
regulation of membrane potential GO:0042391 192 0.073
negative regulation of homeostatic process GO:0032845 71 0.073
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.073
negative regulation of cell proliferation GO:0008285 296 0.073
negative regulation of apoptotic signaling pathway GO:2001234 104 0.072
glycosyl compound metabolic process GO:1901657 246 0.072
positive regulation of leukocyte differentiation GO:1902107 86 0.071
endocytosis GO:0006897 168 0.070
dna recombination GO:0006310 92 0.069
dna metabolic process GO:0006259 303 0.069
cellular metal ion homeostasis GO:0006875 151 0.068
alpha beta t cell activation GO:0046631 91 0.068
reactive oxygen species metabolic process GO:0072593 84 0.067
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.067
regulation of transferase activity GO:0051338 263 0.067
positive regulation of monocyte chemotaxis GO:0090026 2 0.067
peptidyl amino acid modification GO:0018193 336 0.066
morphogenesis of a branching structure GO:0001763 203 0.065
negative regulation of lymphocyte activation GO:0051250 91 0.065
eosinophil activation GO:0043307 1 0.065
regulation of cellular ketone metabolic process GO:0010565 66 0.065
cation homeostasis GO:0055080 212 0.064
cell type specific apoptotic process GO:0097285 268 0.063
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.063
negative regulation of defense response GO:0031348 77 0.062
regulation of protein secretion GO:0050708 82 0.061
regulation of secretion by cell GO:1903530 249 0.061
epithelial cell proliferation GO:0050673 174 0.060
response to organonitrogen compound GO:0010243 246 0.060
regulation of cellular component biogenesis GO:0044087 181 0.060
maintenance of location GO:0051235 89 0.060
regulation of adaptive immune response GO:0002819 90 0.059
purine nucleoside metabolic process GO:0042278 241 0.059
granulocyte migration GO:0097530 43 0.059
pattern recognition receptor signaling pathway GO:0002221 47 0.059
t cell costimulation GO:0031295 14 0.059
detection of fungus GO:0016046 2 0.059
multicellular organismal signaling GO:0035637 91 0.058
ribonucleoside metabolic process GO:0009119 245 0.058
cellular response to dna damage stimulus GO:0006974 207 0.058
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.058
nucleobase containing small molecule metabolic process GO:0055086 352 0.058
positive regulation of behavior GO:0048520 40 0.057
regulation of lymphocyte differentiation GO:0045619 107 0.057
reactive oxygen species biosynthetic process GO:1903409 8 0.057
regulation of inflammatory response GO:0050727 147 0.057
neutrophil migration GO:1990266 37 0.057
natural killer cell mediated immunity GO:0002228 29 0.057
ribonucleotide metabolic process GO:0009259 291 0.056
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.055
purine ribonucleoside metabolic process GO:0046128 241 0.055
regulation of exocytosis GO:0017157 61 0.055
alpha beta t cell activation involved in immune response GO:0002287 31 0.055
alpha beta t cell differentiation GO:0046632 69 0.054
regulation of kinase activity GO:0043549 249 0.054
regulation of monocyte extravasation GO:2000437 2 0.054
phagocytosis GO:0006909 66 0.054
defense response to virus GO:0051607 68 0.054
i kappab kinase nf kappab signaling GO:0007249 85 0.054
innate immune response activating signal transduction GO:0002758 50 0.054
regulation of growth of symbiont in host GO:0044126 19 0.053
regulation of natural killer cell mediated cytotoxicity GO:0042269 19 0.053
divalent inorganic cation transport GO:0072511 178 0.053
positive regulation of apoptotic process GO:0043065 217 0.053
eosinophil activation involved in immune response GO:0002278 1 0.052
ameboidal type cell migration GO:0001667 128 0.052
humoral immune response GO:0006959 57 0.052
forebrain development GO:0030900 302 0.051
regulation of purine nucleotide metabolic process GO:1900542 169 0.051
purine containing compound metabolic process GO:0072521 311 0.050
activation of innate immune response GO:0002218 56 0.050
immunoglobulin mediated immune response GO:0016064 69 0.050
regulation of cellular amine metabolic process GO:0033238 20 0.050
natural killer cell mediated cytotoxicity GO:0042267 29 0.050
necrotic cell death GO:0070265 30 0.050
regulation of cell migration GO:0030334 219 0.050
natural killer cell inhibitory signaling pathway GO:0002769 2 0.049
regulation of leukocyte differentiation GO:1902105 159 0.049
reactive nitrogen species metabolic process GO:2001057 0 0.049
antigen processing and presentation GO:0019882 47 0.049
gland development GO:0048732 330 0.049
positive regulation of cell death GO:0010942 224 0.049
cellular amine metabolic process GO:0044106 44 0.049
regulation of cellular amino acid metabolic process GO:0006521 5 0.048
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.048
carbohydrate derivative biosynthetic process GO:1901137 183 0.048
positive regulation of chemotaxis GO:0050921 38 0.048
detection of yeast GO:0001879 2 0.048
response to molecule of fungal origin GO:0002238 4 0.048
negative regulation of molecular function GO:0044092 258 0.047
small gtpase mediated signal transduction GO:0007264 97 0.047
lymphocyte activation involved in immune response GO:0002285 93 0.047
regulation of natural killer cell mediated immunity GO:0002715 19 0.047
organic cyclic compound catabolic process GO:1901361 295 0.047
positive regulation of programmed cell death GO:0043068 218 0.047
positive regulation of dendritic cell chemotaxis GO:2000510 1 0.047
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.047
blood vessel morphogenesis GO:0048514 285 0.046
divalent metal ion transport GO:0070838 172 0.046
regulation of reactive oxygen species metabolic process GO:2000377 40 0.046
response to interferon gamma GO:0034341 34 0.046
regulation of mapk cascade GO:0043408 248 0.046
regulation of protein kinase activity GO:0045859 232 0.046
regulation of proteolysis GO:0030162 164 0.046
cellular homeostasis GO:0019725 240 0.045
regulation of cytokine secretion GO:0050707 61 0.045
regulation of organelle organization GO:0033043 289 0.045
ribose phosphate metabolic process GO:0019693 291 0.045
monocarboxylic acid metabolic process GO:0032787 191 0.045
t helper 17 cell chemotaxis GO:0035705 1 0.045
interleukin 1 beta secretion GO:0050702 16 0.045
single organism cell adhesion GO:0098602 156 0.044
fat cell differentiation GO:0045444 160 0.044
regulation of b cell activation GO:0050864 81 0.044
nucleoside metabolic process GO:0009116 246 0.044
regulation of homeostatic process GO:0032844 182 0.044
negative regulation of phosphorus metabolic process GO:0010563 184 0.044
eosinophil mediated immunity GO:0002447 1 0.043
monocyte extravasation GO:0035696 2 0.043
regulation of immunoglobulin production GO:0002637 42 0.043
purine ribonucleotide metabolic process GO:0009150 290 0.043
negative regulation of cellular protein metabolic process GO:0032269 247 0.043
regulation of cysteine type endopeptidase activity GO:2000116 65 0.042
metal ion homeostasis GO:0055065 189 0.042
regulation of response to wounding GO:1903034 189 0.042
calcium ion transport GO:0006816 159 0.041
positive regulation of t cell extravasation GO:2000409 2 0.041
lymphocyte apoptotic process GO:0070227 54 0.041
second messenger mediated signaling GO:0019932 73 0.041
cellular response to molecule of fungal origin GO:0071226 2 0.041
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.041
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.040
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.040
granzyme mediated apoptotic signaling pathway GO:0008626 1 0.040
actin cytoskeleton organization GO:0030036 220 0.040
cellular response to acid chemical GO:0071229 68 0.040
tumor necrosis factor production GO:0032640 50 0.040
positive regulation of hydrolase activity GO:0051345 148 0.040
positive regulation of response to wounding GO:1903036 66 0.040
production of molecular mediator of immune response GO:0002440 103 0.040
regulation of lymphocyte mediated immunity GO:0002706 84 0.039
positive regulation of protein phosphorylation GO:0001934 242 0.039
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.039
negative regulation of growth GO:0045926 99 0.039
heterocycle catabolic process GO:0046700 280 0.039
transmission of nerve impulse GO:0019226 76 0.039
regulation of multi organism process GO:0043900 111 0.039
regulation of immune complex clearance by monocytes and macrophages GO:0090264 2 0.038
regulation of intracellular transport GO:0032386 159 0.038
glycoprotein metabolic process GO:0009100 116 0.038
cell recognition GO:0008037 83 0.038
regulation of angiogenesis GO:0045765 81 0.038
t helper cell differentiation GO:0042093 28 0.038
positive regulation of nervous system development GO:0051962 221 0.037
morphogenesis of a branching epithelium GO:0061138 193 0.037
microglial cell activation involved in immune response GO:0002282 1 0.037
t cell activation involved in immune response GO:0002286 43 0.037
purine ribonucleotide catabolic process GO:0009154 208 0.037
multicellular organismal homeostasis GO:0048871 164 0.037
branching morphogenesis of an epithelial tube GO:0048754 159 0.037
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.037
pyridine containing compound catabolic process GO:0072526 4 0.037
t cell differentiation involved in immune response GO:0002292 30 0.036
necroptotic process GO:0070266 21 0.036
positive regulation of interleukin 6 production GO:0032755 37 0.036
positive regulation of lymphocyte differentiation GO:0045621 61 0.036
glycosyl compound catabolic process GO:1901658 206 0.036
carbohydrate metabolic process GO:0005975 230 0.036
positive regulation of immunological synapse formation GO:2000522 1 0.036
regulation of hydrolase activity GO:0051336 246 0.036
protein processing GO:0016485 163 0.036
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526 1 0.035
cellular chemical homeostasis GO:0055082 215 0.035
positive regulation of apoptotic signaling pathway GO:2001235 95 0.035
dendritic cell differentiation GO:0097028 26 0.035
mapk cascade GO:0000165 281 0.035
negative regulation of phosphorylation GO:0042326 166 0.035
response to tumor necrosis factor GO:0034612 26 0.035
organonitrogen compound catabolic process GO:1901565 264 0.035
neutrophil chemotaxis GO:0030593 36 0.035
protein secretion GO:0009306 111 0.034
aromatic compound catabolic process GO:0019439 286 0.034
purine nucleoside catabolic process GO:0006152 205 0.034
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 26 0.034
cellular response to organonitrogen compound GO:0071417 145 0.034
positive regulation of protein modification process GO:0031401 299 0.034
nucleotide catabolic process GO:0009166 217 0.034
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.034
t cell selection GO:0045058 34 0.034
acute inflammatory response GO:0002526 41 0.033
t helper 1 type immune response GO:0042088 25 0.033
homeostasis of number of cells GO:0048872 210 0.033
regulation of cell motility GO:2000145 236 0.033
negative regulation of eosinophil degranulation GO:0043310 1 0.033
regulation of protein complex assembly GO:0043254 83 0.033
negative regulation of chemokine production GO:0032682 4 0.033
negative regulation of leukocyte proliferation GO:0070664 46 0.033
defense response to gram positive bacterium GO:0050830 50 0.033
muscle tissue development GO:0060537 308 0.033
positive regulation of interleukin 2 production GO:0032743 19 0.032
negative regulation of cellular component organization GO:0051129 194 0.032
b cell activation GO:0042113 161 0.032
intracellular protein transport GO:0006886 204 0.032
regulation of interleukin 2 biosynthetic process GO:0045076 13 0.032
regulation of t cell differentiation GO:0045580 83 0.032
muscle cell differentiation GO:0042692 261 0.032
negative regulation of lymphocyte proliferation GO:0050672 45 0.032
kidney development GO:0001822 213 0.032
purine nucleoside triphosphate catabolic process GO:0009146 203 0.032
positive regulation of interleukin 12 production GO:0032735 21 0.032
cellular nitrogen compound catabolic process GO:0044270 280 0.032
peptidyl tyrosine modification GO:0018212 145 0.031
positive regulation of inflammatory response to antigenic stimulus GO:0002863 11 0.031
granulocyte chemotaxis GO:0071621 39 0.031
sensory perception GO:0007600 245 0.031
interspecies interaction between organisms GO:0044419 83 0.031
gliogenesis GO:0042063 141 0.031
negative regulation of phosphate metabolic process GO:0045936 184 0.031
regulation of interleukin 6 production GO:0032675 55 0.031
germ cell development GO:0007281 185 0.030
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.030
lymphocyte costimulation GO:0031294 15 0.030
neuronal action potential GO:0019228 54 0.030
response to growth factor GO:0070848 198 0.030
plasma membrane organization GO:0007009 90 0.030
engulfment of apoptotic cell GO:0043652 3 0.030
leukocyte degranulation GO:0043299 27 0.030
regulation of stress activated mapk cascade GO:0032872 69 0.030
macromolecule catabolic process GO:0009057 281 0.029
cation transport GO:0006812 399 0.029
regulation of vasculature development GO:1901342 88 0.029
epithelial tube morphogenesis GO:0060562 303 0.029
carbohydrate derivative catabolic process GO:1901136 231 0.029
regulation of epithelial cell proliferation GO:0050678 141 0.029
detection of other organism GO:0098543 8 0.029
sensory organ morphogenesis GO:0090596 242 0.029
exocytosis GO:0006887 121 0.029
immune complex clearance GO:0002434 2 0.029
microglial cell activation GO:0001774 3 0.028
cellular protein complex assembly GO:0043623 116 0.028
intrinsic apoptotic signaling pathway GO:0097193 132 0.028
positive regulation of b cell activation GO:0050871 49 0.028
angiogenesis GO:0001525 201 0.028
cell adhesion GO:0007155 329 0.028
b cell activation involved in immune response GO:0002312 50 0.028
b cell proliferation GO:0042100 53 0.028
myeloid leukocyte migration GO:0097529 57 0.028
positive regulation of b cell mediated immunity GO:0002714 26 0.028
negative regulation of multi organism process GO:0043901 68 0.028
cellular response to hormone stimulus GO:0032870 150 0.028
mitotic cell cycle process GO:1903047 159 0.028
cellular response to growth factor stimulus GO:0071363 197 0.028
regulation of b cell mediated immunity GO:0002712 37 0.027
protein maturation GO:0051604 176 0.027
b cell mediated immunity GO:0019724 71 0.027
cell cell recognition GO:0009988 44 0.027
interleukin 8 secretion GO:0072606 3 0.027
negative regulation of macrophage apoptotic process GO:2000110 3 0.027
interleukin 12 production GO:0032615 32 0.027
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.027
negative regulation of regulatory t cell differentiation GO:0045590 2 0.027
placenta development GO:0001890 140 0.027
organophosphate catabolic process GO:0046434 232 0.027
nucleoside triphosphate metabolic process GO:0009141 230 0.027
regulation of eosinophil degranulation GO:0043309 1 0.026
chemokine production GO:0032602 34 0.026
cellular calcium ion homeostasis GO:0006874 119 0.026
immunoglobulin production GO:0002377 73 0.026
negative regulation of immune effector process GO:0002698 55 0.026
response to radiation GO:0009314 165 0.026
regulation of acute inflammatory response GO:0002673 27 0.026
regulation of peptidase activity GO:0052547 96 0.026
regulation of chemokine secretion GO:0090196 4 0.026
skeletal muscle organ development GO:0060538 163 0.026
calcium ion transport into cytosol GO:0060402 48 0.026
purine containing compound catabolic process GO:0072523 213 0.026
regulation of actin filament based process GO:0032970 99 0.026
cognition GO:0050890 149 0.026
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.025
positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 0.025
negative regulation of secretion by cell GO:1903531 54 0.025
jnk cascade GO:0007254 72 0.025
somatic diversification of immune receptors GO:0002200 53 0.025
purine nucleoside triphosphate metabolic process GO:0009144 226 0.025
regulation of regulatory t cell differentiation GO:0045589 7 0.025
leukocyte migration GO:0050900 124 0.025
organic hydroxy compound metabolic process GO:1901615 203 0.025
regulation of cellular catabolic process GO:0031329 242 0.025
regulation of ion homeostasis GO:2000021 64 0.024
endomembrane system organization GO:0010256 147 0.024
negative regulation of t cell activation GO:0050868 65 0.024
somatic diversification of immunoglobulins GO:0016445 43 0.024
positive regulation of protein transport GO:0051222 93 0.024
regulation of hormone levels GO:0010817 211 0.024
ensheathment of neurons GO:0007272 76 0.024
negative regulation of leukocyte apoptotic process GO:2000107 31 0.024
regulation of t helper 1 type immune response GO:0002825 17 0.024
negative regulation of cell cycle GO:0045786 123 0.024
anion transport GO:0006820 177 0.024
myeloid leukocyte mediated immunity GO:0002444 42 0.024
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.024
regulation of protein maturation GO:1903317 96 0.024
regulation of regulated secretory pathway GO:1903305 20 0.023
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.023
ear development GO:0043583 200 0.023
cd4 positive alpha beta t cell activation GO:0035710 45 0.023
regulation of interleukin 8 production GO:0032677 3 0.023
interleukin 18 mediated signaling pathway GO:0035655 2 0.023
cellular divalent inorganic cation homeostasis GO:0072503 127 0.023
regulation of cytoplasmic transport GO:1903649 112 0.023
protein kinase b signaling GO:0043491 74 0.023
mammary gland epithelium development GO:0061180 65 0.023
ras protein signal transduction GO:0007265 77 0.023
regulation of protein serine threonine kinase activity GO:0071900 157 0.023
negative regulation of nervous system development GO:0051961 156 0.023
regulation of interleukin 12 production GO:0032655 30 0.023
t cell migration GO:0072678 19 0.023
myelination GO:0042552 74 0.023
hematopoietic stem cell migration GO:0035701 1 0.023
positive regulation of intracellular transport GO:0032388 70 0.023
nucleoside phosphate catabolic process GO:1901292 222 0.022
cytosolic calcium ion transport GO:0060401 48 0.022
interleukin 1 beta production GO:0032611 30 0.022
protein import into nucleus GO:0006606 95 0.022
immune complex clearance by monocytes and macrophages GO:0002436 2 0.022
negative regulation of kinase activity GO:0033673 81 0.022
myotube differentiation GO:0014902 105 0.022
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.022
calcium ion homeostasis GO:0055074 127 0.022
striated muscle tissue development GO:0014706 293 0.022
modulation of growth of symbiont involved in interaction with host GO:0044144 19 0.022
myeloid dendritic cell differentiation GO:0043011 16 0.022
positive regulation of tumor necrosis factor production GO:0032760 30 0.022
monosaccharide transport GO:0015749 58 0.022
establishment of organelle localization GO:0051656 122 0.022
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.022
interleukin 10 secretion GO:0072608 4 0.022
immunoglobulin secretion GO:0048305 17 0.022
regulation of cellular response to stress GO:0080135 159 0.022
muscle contraction GO:0006936 101 0.022
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 16 0.021
ribonucleoside catabolic process GO:0042454 206 0.021
protein catabolic process GO:0030163 221 0.021
axonogenesis GO:0007409 274 0.021
nuclear transport GO:0051169 139 0.021
action potential GO:0001508 78 0.021
regulation of cytoskeleton organization GO:0051493 122 0.021
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.021
circulatory system process GO:0003013 197 0.021
regulation of interleukin 1 beta secretion GO:0050706 15 0.021
positive regulation of immune complex clearance by monocytes and macrophages GO:0090265 2 0.021
positive regulation of protein kinase b signaling GO:0051897 32 0.021

Il2ra disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.047
musculoskeletal system disease DOID:17 0 0.047
immune system disease DOID:2914 0 0.034
cancer DOID:162 0 0.025
disease of cellular proliferation DOID:14566 0 0.025