IMP

Process View

Mus musculus

13 genes annotated in mouse

regulation of interleukin 2 biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-2.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of interleukin 2 biosynthetic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of interleukin 2 biosynthetic process" (in gray)

Name	Description	Probability	Func Analog Organism
Icos	inducible T-cell co-stimulator	0.996	Mouse
Cd80	CD80 antigen	0.913
Stat5a	signal transducer and activator of transcription 5A	0.912
Cd28	CD28 antigen	0.811
Stat5b	signal transducer and activator of transcription 5B	0.798
Irf9	interferon regulatory factor 9	0.632
Pdcd1	programmed cell death 1	0.621
Sh2d1a	SH2 domain protein 1A	0.474
Tnf	tumor necrosis factor	0.414
Batf	basic leucine zipper transcription factor, ATF-like	0.406
Ccr7	chemokine (C-C motif) receptor 7	0.246
Cd5	CD5 antigen	0.241
Cd40	CD40 antigen	0.173
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.172
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.143
Il4	interleukin 4	0.122
Stat1	signal transducer and activator of transcription 1	0.122	Mouse
Pparg	peroxisome proliferator activated receptor gamma	0.120
Traf1	TNF receptor-associated factor 1	0.116
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.114
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.112
Ikzf3	IKAROS family zinc finger 3	0.107
Il4ra	interleukin 4 receptor, alpha	0.103
Tnfrsf13b	tumor necrosis factor receptor superfamily, member 13b	0.101
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.098	Mouse
Il21r	interleukin 21 receptor	0.094
Ifng	interferon gamma	0.088
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.086
Stat2	signal transducer and activator of transcription 2	0.082	Mouse
Il1a	interleukin 1 alpha	0.075	Human
Cd19	CD19 antigen	0.065
Gli2	GLI-Kruppel family member GLI2	0.064
Trim21	tripartite motif-containing 21	0.063
Il27ra	interleukin 27 receptor, alpha	0.062
Il6st	interleukin 6 signal transducer	0.059
Cd6	CD6 antigen	0.059
Akt1	thymoma viral proto-oncogene 1	0.054	Mouse
Rhoh	ras homolog gene family, member H	0.049
Lta	lymphotoxin A	0.046
Il6	interleukin 6	0.044
Casp1	caspase 1	0.042
Itk	IL2-inducible T-cell kinase	0.041
Cd27	CD27 antigen	0.040
Socs1	suppressor of cytokine signaling 1	0.039
Clec4n	C-type lectin domain family 4, member n	0.038
Foxp3	forkhead box P3	0.038
Cxcl9	chemokine (C-X-C motif) ligand 9	0.037
Actn2	actinin alpha 2	0.037
Sh2d2a	SH2 domain protein 2A	0.036
Foxp2	forkhead box P2	0.035	Mouse
Cd2	CD2 antigen	0.035
Ccl22	chemokine (C-C motif) ligand 22	0.033
Tnfrsf18	tumor necrosis factor receptor superfamily, member 18	0.033
Irf4	interferon regulatory factor 4	0.033	Human
Il2ra	interleukin 2 receptor, alpha chain	0.032
Nckap1l	NCK associated protein 1 like	0.032
Mapkapk2	MAP kinase-activated protein kinase 2	0.031
Ccr9	chemokine (C-C motif) receptor 9	0.031
Prkcq	protein kinase C, theta	0.028
Il10	interleukin 10	0.028
Plp1	proteolipid protein (myelin) 1	0.025
Cd4	CD4 antigen	0.025
Stat3	signal transducer and activator of transcription 3	0.025	Mouse
Ldb3	LIM domain binding 3	0.024
Foxp1	forkhead box P1	0.024	Mouse
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.024
Slamf1	signaling lymphocytic activation molecule family member 1	0.023
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.023
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.023
Cd3e	CD3 antigen, epsilon polypeptide	0.022
Il1r1	interleukin 1 receptor, type I	0.022
Ifnar2	interferon (alpha and beta) receptor 2	0.021
Vav1	vav 1 oncogene	0.021
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.020
Nlrp3	NLR family, pyrin domain containing 3	0.020
Igh	immunoglobulin heavy chain complex	0.019
Myd88	myeloid differentiation primary response gene 88	0.019
Lyz2	lysozyme 2	0.019
Prf1	perforin 1 (pore forming protein)	0.019
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.018
Cd3g	CD3 antigen, gamma polypeptide	0.018	Mouse
Cd7	CD7 antigen	0.018
Akt2	thymoma viral proto-oncogene 2	0.017	Mouse
Cd3d	CD3 antigen, delta polypeptide	0.017	Mouse
Prlr	prolactin receptor	0.017
Kit	kit oncogene	0.017
Zap70	zeta-chain (TCR) associated protein kinase	0.016
Adar	adenosine deaminase, RNA-specific	0.016
Cd96	CD96 antigen	0.015
Sell	selectin, lymphocyte	0.015
Rel	reticuloendotheliosis oncogene	0.015
Agap2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	0.014
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.014
Ncoa3	nuclear receptor coactivator 3	0.014
Xcl1	chemokine (C motif) ligand 1	0.014
Sp110	Sp110 nuclear body protein	0.014
Tbx21	T-box 21	0.014
Gfi1	growth factor independent 1	0.014
Mobp	myelin-associated oligodendrocytic basic protein	0.014
Rag2	recombination activating gene 2	0.013
Stat4	signal transducer and activator of transcription 4	0.013	Mouse
Cst7	cystatin F (leukocystatin)	0.013
Cd72	CD72 antigen	0.013
Fasl	Fas ligand (TNF superfamily, member 6)	0.013
Ly9	lymphocyte antigen 9	0.013
Il2	interleukin 2	0.013
Cxcr6	chemokine (C-X-C motif) receptor 6	0.013
Capn1	calpain 1	0.012
Il7r	interleukin 7 receptor	0.012
Tapbp	TAP binding protein	0.012
Btk	Bruton agammaglobulinemia tyrosine kinase	0.012
Bcl6	B-cell leukemia/lymphoma 6	0.012
Jak1	Janus kinase 1	0.012
Rc3h1	RING CCCH (C3H) domains 1	0.012
Cd79a	CD79A antigen (immunoglobulin-associated alpha)	0.012
Il1b	interleukin 1 beta	0.012	Human
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.012
Slamf6	SLAM family member 6	0.011
Blnk	B-cell linker	0.011
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.011
Nfil3	nuclear factor, interleukin 3, regulated	0.011
Bcl2a1d	B-cell leukemia/lymphoma 2 related protein A1d	0.011
Sfpi1	SFFV proviral integration 1	0.010
Gimap7	GTPase, IMAP family member 7	0.010