Mus musculus

90 known processes

Il2rg

interleukin 2 receptor, gamma chain

(Aliases: gamma(c),[g]c,CD132,gc)

Il2rg biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
leukocyte differentiation GO:0002521 342 0.998
t cell receptor signaling pathway GO:0050852 46 0.995
t cell differentiation GO:0030217 174 0.993
cytokine production GO:0001816 319 0.992
regulation of cell activation GO:0050865 289 0.992
leukocyte homeostasis GO:0001776 79 0.990
positive regulation of t cell mediated cytotoxicity GO:0001916 15 0.985
positive regulation of gamma delta t cell differentiation GO:0045588 6 0.984
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.983
leukocyte activation involved in immune response GO:0002366 126 0.983
immune response activating signal transduction GO:0002757 116 0.981
negative regulation of adaptive immune response GO:0002820 25 0.979
cellular response to molecule of bacterial origin GO:0071219 83 0.973
leukocyte mediated immunity GO:0002443 174 0.972
fc epsilon receptor signaling pathway GO:0038095 3 0.972
regulation of hematopoietic stem cell migration GO:2000471 1 0.970
regulation of t cell mediated cytotoxicity GO:0001914 18 0.965
negative regulation of t cell mediated cytotoxicity GO:0001915 3 0.952
extrinsic apoptotic signaling pathway GO:0097191 126 0.944
t cell differentiation in thymus GO:0033077 77 0.943
positive regulation of type iii hypersensitivity GO:0001805 3 0.941
regulation of cytokine production GO:0001817 266 0.937
b cell activation involved in immune response GO:0002312 50 0.936
homeostasis of number of cells GO:0048872 210 0.935
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.928
cellular amine metabolic process GO:0044106 44 0.928
production of molecular mediator of immune response GO:0002440 103 0.927
antigen receptor mediated signaling pathway GO:0050851 64 0.927
lymph node development GO:0048535 18 0.924
lymphocyte mediated immunity GO:0002449 139 0.917
cell killing GO:0001906 67 0.914
positive regulation of cytokine production GO:0001819 174 0.914
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.909
positive regulation of apoptotic signaling pathway GO:2001235 95 0.897
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.891
immunoglobulin mediated immune response GO:0016064 69 0.889
adaptive immune response GO:0002250 155 0.886
immune effector process GO:0002252 321 0.884
cell activation involved in immune response GO:0002263 126 0.882
positive regulation of isotype switching to igg isotypes GO:0048304 7 0.879
positive regulation of cellular amine metabolic process GO:0033240 5 0.878
regulation of t cell differentiation GO:0045580 83 0.878
lymphocyte activation involved in immune response GO:0002285 93 0.878
defense response to other organism GO:0098542 197 0.877
isotype switching to igg isotypes GO:0048291 10 0.875
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.871
lymphocyte homeostasis GO:0002260 64 0.869
b cell activation GO:0042113 161 0.867
mast cell activation GO:0045576 27 0.863
defense response to virus GO:0051607 68 0.854
t cell activation GO:0042110 289 0.854
regulation of toll like receptor 2 signaling pathway GO:0034135 3 0.832
calcium ion transport GO:0006816 159 0.827
interleukin 2 mediated signaling pathway GO:0038110 2 0.822
regulation of mast cell activation GO:0033003 21 0.821
serotonin production involved in inflammatory response GO:0002351 4 0.816
myeloid leukocyte differentiation GO:0002573 119 0.815
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.812
regulation of adaptive immune response GO:0002819 90 0.804
response to peptide hormone GO:0043434 127 0.792
regulation of cytokine production involved in immune response GO:0002718 26 0.789
regulation of lymphocyte differentiation GO:0045619 107 0.782
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 36 0.780
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.774
metal ion homeostasis GO:0055065 189 0.773
cellular response to lipopolysaccharide GO:0071222 77 0.764
regulation of cellular amine metabolic process GO:0033238 20 0.752
cell fate commitment GO:0045165 210 0.745
amine metabolic process GO:0009308 45 0.744
positive regulation of inflammatory response to antigenic stimulus GO:0002863 11 0.743
regulation of lymphocyte activation GO:0051249 240 0.736
positive regulation of hydrolase activity GO:0051345 148 0.735
acute inflammatory response to antigenic stimulus GO:0002438 12 0.730
apoptotic signaling pathway GO:0097190 306 0.729
hematopoietic stem cell migration GO:0035701 1 0.727
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.723
cytosolic calcium ion transport GO:0060401 48 0.719
regulation of antimicrobial humoral response GO:0002759 3 0.719
b cell differentiation GO:0030183 78 0.710
regulation of dendritic cell apoptotic process GO:2000668 3 0.707
fc receptor mediated stimulatory signaling pathway GO:0002431 4 0.706
t cell mediated cytotoxicity GO:0001913 26 0.703
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 0.703
positive regulation of lymphocyte activation GO:0051251 140 0.703
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.698
regulation of leukocyte proliferation GO:0070663 121 0.696
regulation of tolerance induction dependent upon immune response GO:0002652 1 0.695
innate immune response GO:0045087 157 0.694
positive regulation of defense response GO:0031349 124 0.690
cytokine mediated signaling pathway GO:0019221 115 0.686
alpha beta t cell activation GO:0046631 91 0.674
regulation of tyrosine phosphorylation of stat5 protein GO:0042522 8 0.672
alpha beta t cell differentiation GO:0046632 69 0.670
activation of immune response GO:0002253 138 0.665
regulation of leukocyte mediated immunity GO:0002703 104 0.661
myeloid cell homeostasis GO:0002262 114 0.657
divalent inorganic cation homeostasis GO:0072507 138 0.649
cellular amino acid metabolic process GO:0006520 103 0.647
tyrosine phosphorylation of stat5 protein GO:0042506 9 0.645
positive regulation of adaptive immune response GO:0002821 61 0.644
positive regulation of t cell activation GO:0050870 101 0.641
regulation of cellular ketone metabolic process GO:0010565 66 0.639
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.635
inflammatory response GO:0006954 244 0.632
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.632
cytokine production involved in immune response GO:0002367 34 0.631
calcium ion homeostasis GO:0055074 127 0.628
regulation of regulated secretory pathway GO:1903305 20 0.627
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.624
regulation of interleukin 10 production GO:0032653 21 0.623
antigen processing and presentation of peptide antigen via mhc class i GO:0002474 9 0.611
leukocyte proliferation GO:0070661 172 0.609
regulation of intracellular transport GO:0032386 159 0.600
lymphocyte differentiation GO:0030098 242 0.600
regulation of cellular amino acid metabolic process GO:0006521 5 0.599
positive regulation of innate immune response GO:0045089 80 0.598
cellular response to lipid GO:0071396 145 0.595
cellular homeostasis GO:0019725 240 0.572
regulation of mapk cascade GO:0043408 248 0.571
regulation of myeloid leukocyte differentiation GO:0002761 58 0.564
negative regulation of cell adhesion involved in substrate bound cell migration GO:0006933 3 0.562
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 26 0.559
positive regulation of podosome assembly GO:0071803 3 0.557
negative regulation of protein metabolic process GO:0051248 282 0.554
myeloid cell differentiation GO:0030099 233 0.544
myeloid leukocyte migration GO:0097529 57 0.530
t cell proliferation GO:0042098 120 0.515
immune response regulating signaling pathway GO:0002764 125 0.514
defense response to gram positive bacterium GO:0050830 50 0.513
negative regulation of homeostatic process GO:0032845 71 0.512
regulation of tumor necrosis factor production GO:0032680 49 0.511
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.506
positive regulation of hematopoietic stem cell migration GO:2000473 1 0.505
positive regulation of leukocyte proliferation GO:0070665 73 0.505
neutrophil activation involved in immune response GO:0002283 8 0.500
regulation of toll like receptor 4 signaling pathway GO:0034143 4 0.500
maintenance of location GO:0051235 89 0.498
regulation of production of molecular mediator of immune response GO:0002700 65 0.497
regulation of leukocyte apoptotic process GO:2000106 56 0.495
regulation of immunoglobulin mediated immune response GO:0002889 37 0.494
fc receptor signaling pathway GO:0038093 6 0.490
lymphocyte proliferation GO:0046651 164 0.488
cellular ketone metabolic process GO:0042180 84 0.487
cation transport GO:0006812 399 0.484
leukocyte migration GO:0050900 124 0.481
positive regulation of myeloid leukocyte mediated immunity GO:0002888 14 0.480
positive regulation of antigen receptor mediated signaling pathway GO:0050857 9 0.478
positive regulation of lymphocyte proliferation GO:0050671 70 0.477
regulation of inflammatory response to antigenic stimulus GO:0002861 21 0.473
regulation of t cell proliferation GO:0042129 92 0.472
leukocyte mediated cytotoxicity GO:0001909 62 0.470
leukocyte apoptotic process GO:0071887 71 0.470
gamma delta t cell differentiation GO:0042492 11 0.464
tyrosine phosphorylation of stat protein GO:0007260 23 0.462
cytosolic calcium ion homeostasis GO:0051480 70 0.456
positive regulation of cell activation GO:0050867 158 0.451
dna recombination GO:0006310 92 0.449
inflammatory response to antigenic stimulus GO:0002437 30 0.439
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.439
positive regulation of endopeptidase activity GO:0010950 43 0.436
i kappab kinase nf kappab signaling GO:0007249 85 0.436
positive regulation of leukocyte differentiation GO:1902107 86 0.428
regulation of innate immune response GO:0045088 91 0.426
regulation of alpha beta t cell differentiation GO:0046637 35 0.426
immune response inhibiting signal transduction GO:0002765 4 0.426
circadian rhythm GO:0007623 114 0.422
carbohydrate derivative biosynthetic process GO:1901137 183 0.422
positive regulation of immune effector process GO:0002699 107 0.421
tumor necrosis factor production GO:0032640 50 0.419
positive regulation of translational initiation GO:0045948 4 0.418
toll like receptor 4 signaling pathway GO:0034142 9 0.416
dendritic cell differentiation GO:0097028 26 0.413
protein localization to nucleus GO:0034504 121 0.412
blood coagulation GO:0007596 76 0.410
erk1 and erk2 cascade GO:0070371 77 0.409
regulation of type ii hypersensitivity GO:0002892 4 0.408
glycoprotein metabolic process GO:0009100 116 0.405
negative regulation of glycoprotein metabolic process GO:1903019 3 0.404
myeloid leukocyte activation GO:0002274 83 0.404
positive regulation of intracellular transport GO:0032388 70 0.402
regulation of homeostatic process GO:0032844 182 0.400
regulation of platelet activation GO:0010543 17 0.399
regulation of cell killing GO:0031341 40 0.395
pattern recognition receptor signaling pathway GO:0002221 47 0.394
cellular response to platelet derived growth factor stimulus GO:0036120 5 0.390
serotonin secretion involved in inflammatory response GO:0002442 4 0.389
positive regulation of b cell activation GO:0050871 49 0.388
small gtpase mediated signal transduction GO:0007264 97 0.386
dna metabolic process GO:0006259 303 0.386
cellular ion homeostasis GO:0006873 165 0.385
axon guidance GO:0007411 141 0.383
peptidyl amino acid modification GO:0018193 336 0.382
somatic diversification of immune receptors GO:0002200 53 0.379
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 1 0.373
regulation of protein localization GO:0032880 231 0.366
response to organonitrogen compound GO:0010243 246 0.364
negative regulation of t helper 1 cell differentiation GO:0045626 3 0.361
integrin mediated signaling pathway GO:0007229 27 0.361
positive regulation of t cell differentiation GO:0045582 52 0.353
positive regulation of b cell mediated immunity GO:0002714 26 0.351
defense response to bacterium GO:0042742 119 0.351
g protein coupled receptor signaling pathway GO:0007186 243 0.350
negative regulation of toll like receptor signaling pathway GO:0034122 14 0.347
response to lipopolysaccharide GO:0032496 128 0.347
reactive oxygen species metabolic process GO:0072593 84 0.346
b cell mediated immunity GO:0019724 71 0.346
cytoplasmic transport GO:0016482 234 0.345
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 15 0.345
compound eye development GO:0048749 1 0.344
neutrophil activation GO:0042119 9 0.336
negative regulation of cell proliferation GO:0008285 296 0.336
t cell mediated immunity GO:0002456 50 0.335
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.333
regulation of lymphocyte mediated immunity GO:0002706 84 0.330
cellular response to peptide GO:1901653 92 0.326
regulation of antimicrobial peptide production GO:0002784 1 0.325
regulation of b cell proliferation GO:0030888 39 0.325
cellular response to biotic stimulus GO:0071216 92 0.325
response to molecule of bacterial origin GO:0002237 143 0.324
innate immune response activating signal transduction GO:0002758 50 0.324
negative regulation of inflammatory response to antigenic stimulus GO:0002862 10 0.323
mucosal associated lymphoid tissue development GO:0048537 12 0.323
dephosphorylation GO:0016311 129 0.322
regulation of kinase activity GO:0043549 249 0.320
regulation of defense response GO:0031347 233 0.319
positive regulation of mapk cascade GO:0043410 170 0.316
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.315
activation of cysteine type endopeptidase activity GO:0097202 27 0.306
regulation of ion transport GO:0043269 215 0.304
regulation of cysteine type endopeptidase activity GO:2000116 65 0.304
regulation of type iia hypersensitivity GO:0001796 4 0.301
negative regulation of b cell proliferation GO:0030889 13 0.299
positive regulation of phospholipase c activity GO:0010863 2 0.297
regulation of apoptotic signaling pathway GO:2001233 197 0.295
apical constriction GO:0003383 4 0.295
regulation of multi organism process GO:0043900 111 0.295
isotype switching GO:0045190 36 0.289
negative regulation of leukocyte proliferation GO:0070664 46 0.288
cell type specific apoptotic process GO:0097285 268 0.284
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.279
positive regulation of proteolysis GO:0045862 85 0.279
positive regulation of growth hormone receptor signaling pathway GO:0060399 3 0.278
positive regulation of secretion by cell GO:1903532 114 0.277
regulation of lymphocyte proliferation GO:0050670 117 0.271
negative regulation of phosphate metabolic process GO:0045936 184 0.271
reactive nitrogen species metabolic process GO:2001057 0 0.271
regionalization GO:0003002 337 0.269
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.268
positive regulation of leukocyte apoptotic process GO:2000108 21 0.266
regulation of hydrolase activity GO:0051336 246 0.264
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.259
negative regulation of t cell apoptotic process GO:0070233 18 0.257
regulation of toll like receptor signaling pathway GO:0034121 20 0.257
positive regulation of calcium mediated signaling GO:0050850 15 0.253
mapk cascade GO:0000165 281 0.253
negative regulation of interleukin 12 production GO:0032695 10 0.253
positive regulation of cell migration GO:0030335 109 0.247
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.247
negative regulation of leukocyte mediated immunity GO:0002704 29 0.246
neutrophil differentiation GO:0030223 3 0.244
positive regulation of cell death GO:0010942 224 0.243
signal transduction in absence of ligand GO:0038034 55 0.243
cation homeostasis GO:0055080 212 0.241
positive regulation of dendritic cell apoptotic process GO:2000670 3 0.240
endodermal cell fate specification GO:0001714 4 0.239
regulation of cell migration GO:0030334 219 0.238
positive regulation of stress activated mapk cascade GO:0032874 48 0.238
regulation of acute inflammatory response GO:0002673 27 0.235
platelet degranulation GO:0002576 6 0.233
cellular metal ion homeostasis GO:0006875 151 0.232
regulation of t cell activation GO:0050863 170 0.232
negative regulation of map kinase activity GO:0043407 34 0.232
positive regulation of b cell receptor signaling pathway GO:0050861 4 0.232
positive regulation of alpha beta t cell activation GO:0046635 39 0.231
regulation of humoral immune response GO:0002920 22 0.230
negative regulation of protein modification process GO:0031400 163 0.229
regulation of mast cell activation involved in immune response GO:0033006 17 0.226
actin filament based movement GO:0030048 23 0.226
cellular zinc ion homeostasis GO:0006882 9 0.226
regulation of endopeptidase activity GO:0052548 89 0.226
somatic diversification of immunoglobulins GO:0016445 43 0.226
positive regulation of dna recombination GO:0045911 17 0.224
type i hypersensitivity GO:0016068 4 0.224
positive regulation of cell killing GO:0031343 33 0.222
regulation of cell motility GO:2000145 236 0.222
interferon gamma production GO:0032609 67 0.221
immunoglobulin production GO:0002377 73 0.220
regulation of binding GO:0051098 111 0.219
regulation of cytoplasmic transport GO:1903649 112 0.219
t cell differentiation involved in immune response GO:0002292 30 0.219
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.219
regulation of myeloid cell differentiation GO:0045637 96 0.218
phospholipid metabolic process GO:0006644 87 0.217
regulation of b cell mediated immunity GO:0002712 37 0.211
positive regulation of leukocyte mediated immunity GO:0002705 70 0.210
response to metal ion GO:0010038 47 0.207
actin cytoskeleton organization GO:0030036 220 0.205
regulation of ion homeostasis GO:2000021 64 0.203
positive regulation of immunoglobulin mediated immune response GO:0002891 26 0.202
positive regulation of tyrosine phosphorylation of stat5 protein GO:0042523 6 0.202
coagulation GO:0050817 78 0.198
positive regulation of exocytosis GO:0045921 20 0.198
antigen processing and presentation of exogenous peptide antigen GO:0002478 21 0.197
filtration diaphragm assembly GO:0036058 1 0.197
negative regulation of leukocyte apoptotic process GO:2000107 31 0.195
positive regulation of protein phosphorylation GO:0001934 242 0.195
negative regulation of cytokine production GO:0001818 84 0.195
negative regulation of lymphocyte proliferation GO:0050672 45 0.194
regulation of t cell receptor signaling pathway GO:0050856 21 0.194
negative regulation of protein phosphorylation GO:0001933 126 0.192
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.192
erythrocyte differentiation GO:0030218 88 0.192
positive regulation of t cell proliferation GO:0042102 52 0.188
granulocyte activation GO:0036230 10 0.187
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.187
cellular divalent inorganic cation homeostasis GO:0072503 127 0.187
gamma delta t cell activation GO:0046629 13 0.183
positive regulation of regulatory t cell differentiation GO:0045591 4 0.183
mast cell activation involved in immune response GO:0002279 20 0.183
gland development GO:0048732 330 0.182
defense response to fungus GO:0050832 12 0.181
regulation of hypersensitivity GO:0002883 10 0.180
serotonin secretion by platelet GO:0002554 3 0.179
regulation of natural killer cell activation GO:0032814 22 0.177
regulation of reactive oxygen species metabolic process GO:2000377 40 0.177
positive regulation of map kinase activity GO:0043406 84 0.176
regulation of peptidase activity GO:0052547 96 0.175
regulation of map kinase activity GO:0043405 120 0.175
negative regulation of t cell mediated immunity GO:0002710 9 0.175
regulation of type iii hypersensitivity GO:0001803 3 0.175
regulation of neutrophil differentiation GO:0045658 2 0.174
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.174
positive regulation of myeloid leukocyte cytokine production involved in immune response GO:0061081 9 0.174
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.171
cellular response to organonitrogen compound GO:0071417 145 0.171
positive regulation of programmed cell death GO:0043068 218 0.170
placenta development GO:0001890 140 0.170
zymogen activation GO:0031638 41 0.170
regulation of stem cell proliferation GO:0072091 78 0.168
positive regulation of t cell mediated immunity GO:0002711 24 0.166
chemotaxis GO:0006935 247 0.166
regulation of chemokine production GO:0032642 30 0.165
negative regulation of phosphorus metabolic process GO:0010563 184 0.164
positive regulation of antibacterial peptide biosynthetic process GO:0006963 1 0.164
cell adhesion GO:0007155 329 0.164
b cell proliferation GO:0042100 53 0.164
regulation of body fluid levels GO:0050878 162 0.163
somatic cell dna recombination GO:0016444 51 0.162
negative regulation of leukocyte differentiation GO:1902106 51 0.162
negative regulation of toll like receptor 2 signaling pathway GO:0034136 3 0.161
alpha beta t cell proliferation GO:0046633 21 0.160
ras protein signal transduction GO:0007265 77 0.158
antigen processing and presentation of exogenous peptide antigen via mhc class i GO:0042590 6 0.158
negative regulation of protein catabolic process GO:0042177 36 0.157
negative regulation of myeloid cell differentiation GO:0045638 38 0.157
regulation of exocytosis GO:0017157 61 0.157
protein targeting GO:0006605 143 0.156
dendritic cell apoptotic process GO:0097048 3 0.156
monosaccharide transport GO:0015749 58 0.156
positive regulation of canonical wnt signaling pathway GO:0090263 29 0.156
peptidyl tyrosine phosphorylation GO:0018108 143 0.155
cellular response to peptide hormone stimulus GO:0071375 92 0.155
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.155
defense response to gram negative bacterium GO:0050829 28 0.154
regulation of cd4 positive alpha beta t cell differentiation GO:0043370 21 0.154
regulation of response to wounding GO:1903034 189 0.154
positive regulation of cell development GO:0010720 237 0.154
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 2 0.153
cellular chemical homeostasis GO:0055082 215 0.151
activation of innate immune response GO:0002218 56 0.151
regulation of inflammatory response GO:0050727 147 0.150
membrane organization GO:0061024 245 0.150
negative regulation of inflammatory response GO:0050728 61 0.149
protein maturation GO:0051604 176 0.149
regulation of interferon gamma production GO:0032649 57 0.149
regulation of cd4 positive alpha beta t cell activation GO:2000514 24 0.148
divalent inorganic cation transport GO:0072511 178 0.146
mast cell proliferation GO:0070662 4 0.146
regulation of b cell differentiation GO:0045577 23 0.144
regulation of tyrosine phosphorylation of stat protein GO:0042509 20 0.142
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.142
fc receptor mediated inhibitory signaling pathway GO:0002774 1 0.142
protein autophosphorylation GO:0046777 61 0.141
positive regulation of acute inflammatory response GO:0002675 16 0.140
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 27 0.140
regulation of leukocyte differentiation GO:1902105 159 0.140
positive regulation of type ii hypersensitivity GO:0002894 4 0.140
b cell receptor signaling pathway GO:0050853 20 0.139
negative regulation of lymphocyte activation GO:0051250 91 0.139
positive regulation of protein kinase activity GO:0045860 144 0.138
negative regulation of b cell activation GO:0050869 27 0.138
cell chemotaxis GO:0060326 81 0.138
protein processing GO:0016485 163 0.137
divalent metal ion transport GO:0070838 172 0.137
regulation of cellular component size GO:0032535 121 0.137
tolerance induction to self antigen GO:0002513 4 0.137
protein localization to organelle GO:0033365 185 0.136
negative regulation of interleukin 5 production GO:0032714 4 0.136
nitrogen compound transport GO:0071705 271 0.136
positive regulation of response to wounding GO:1903036 66 0.135
nuclear transport GO:0051169 139 0.133
transition metal ion homeostasis GO:0055076 54 0.131
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.129
negative regulation of immune system process GO:0002683 209 0.129
positive regulation of chronic inflammatory response to antigenic stimulus GO:0002876 2 0.128
regulation of humoral immune response mediated by circulating immunoglobulin GO:0002923 10 0.128
positive regulation of jun kinase activity GO:0043507 30 0.128
response to peptide GO:1901652 136 0.127
intracellular receptor signaling pathway GO:0030522 74 0.127
regulation of alpha beta t cell activation GO:0046634 53 0.124
positive regulation of t cell differentiation in thymus GO:0033089 13 0.124
negative regulation of t cell proliferation GO:0042130 38 0.123
regulation of activated t cell proliferation GO:0046006 16 0.122
positive regulation of interleukin 6 production GO:0032755 37 0.122
positive regulation of peptidase activity GO:0010952 49 0.121
parallel actin filament bundle assembly GO:0030046 2 0.120
hypersensitivity GO:0002524 10 0.120
endomembrane system organization GO:0010256 147 0.119
positive regulation of myeloid cell differentiation GO:0045639 43 0.119
activation of janus kinase activity GO:0042976 2 0.118
cellularization GO:0007349 1 0.117
immune response inhibiting cell surface receptor signaling pathway GO:0002767 3 0.117
positive regulation of chemotaxis GO:0050921 38 0.117
antigen processing and presentation GO:0019882 47 0.117
regulation of t helper 1 cell differentiation GO:0045625 7 0.116
maternal placenta development GO:0001893 20 0.115
negative regulation of mast cell apoptotic process GO:0033026 4 0.115
developmental maturation GO:0021700 193 0.115
regulation of dendritic cell cytokine production GO:0002730 2 0.115
regulation of transferase activity GO:0051338 263 0.113
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.113
regulation of cytoskeleton organization GO:0051493 122 0.112
single organismal cell cell adhesion GO:0016337 131 0.112
single organism cell adhesion GO:0098602 156 0.112
osteoclast proliferation GO:0002158 4 0.112
intrinsic apoptotic signaling pathway GO:0097193 132 0.111
regulation of protein catabolic process GO:0042176 108 0.111
osteoclast differentiation GO:0030316 62 0.110
organonitrogen compound biosynthetic process GO:1901566 192 0.109
regulation of protein kinase activity GO:0045859 232 0.109
reactive oxygen species biosynthetic process GO:1903409 8 0.108
sensory perception GO:0007600 245 0.108
leukocyte chemotaxis GO:0030595 69 0.105
positive regulation of phospholipase activity GO:0010518 3 0.105
positive regulation of b cell proliferation GO:0030890 24 0.104
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.104
regulation of cell projection assembly GO:0060491 38 0.103
multicellular organismal homeostasis GO:0048871 164 0.102
exocytosis GO:0006887 121 0.102
regulation of protein serine threonine kinase activity GO:0071900 157 0.101
antigen processing and presentation of exogenous antigen GO:0019884 26 0.100
macromolecule catabolic process GO:0009057 281 0.100
myeloid leukocyte cytokine production GO:0061082 12 0.099
activation of mapk activity GO:0000187 59 0.099
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 18 0.099
positive regulation of alpha beta t cell proliferation GO:0046641 12 0.098
regulation of glucose transport GO:0010827 32 0.098
positive regulation of acute inflammatory response to antigenic stimulus GO:0002866 7 0.098
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.097
eosinophil degranulation GO:0043308 1 0.097
regulation of t cell mediated immunity GO:0002709 34 0.097
regulation of jnk cascade GO:0046328 62 0.096
positive regulation of syncytium formation by plasma membrane fusion GO:0060143 17 0.095
regulation of homotypic cell cell adhesion GO:0034110 13 0.094
establishment of organelle localization GO:0051656 122 0.094
interleukin 6 production GO:0032635 58 0.094
membrane invagination GO:0010324 17 0.093
organic hydroxy compound metabolic process GO:1901615 203 0.093
wound healing GO:0042060 157 0.093
stem cell development GO:0048864 219 0.092
antibacterial peptide production GO:0002778 2 0.092
mast cell homeostasis GO:0033023 5 0.092
osteoclast development GO:0036035 9 0.092
sequestering of metal ion GO:0051238 19 0.091
cd4 positive alpha beta t cell activation GO:0035710 45 0.090
negative regulation of cellular protein metabolic process GO:0032269 247 0.089
regulation of coagulation GO:0050818 31 0.089
positive regulation of protein modification process GO:0031401 299 0.089
negative regulation of toll like receptor 4 signaling pathway GO:0034144 3 0.088
positive regulation of defense response to virus by host GO:0002230 6 0.088
interleukin 17 production GO:0032620 11 0.087
humoral immune response mediated by circulating immunoglobulin GO:0002455 14 0.087
positive regulation of mast cell activation involved in immune response GO:0033008 10 0.087
regulation of interleukin 6 production GO:0032675 55 0.086
digestive tract morphogenesis GO:0048546 147 0.086
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.085
positive regulation of secretion GO:0051047 130 0.085
acute inflammatory response GO:0002526 41 0.085
regulation of interleukin 17 production GO:0032660 8 0.085
regulation of protein binding GO:0043393 60 0.085
regulation of defense response to bacterium GO:1900424 3 0.085
regulation of chemotaxis GO:0050920 53 0.084
myeloid cell activation involved in immune response GO:0002275 34 0.084
jnk cascade GO:0007254 72 0.083
muscle tissue development GO:0060537 308 0.083
negative regulation of molecular function GO:0044092 258 0.083
negative regulation of lymphocyte mediated immunity GO:0002707 21 0.083
hemostasis GO:0007599 78 0.082
regulation of myeloid leukocyte mediated immunity GO:0002886 25 0.082
regulation of mast cell degranulation GO:0043304 16 0.082

Il2rg disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org